LOCUS       c00023_NZ_AUJG..       15903 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AUJG01000024.1 Lachnospira multipara ATCC 19207
            G600DRAFT_scaffold00023.23_C, whole genome shotgun sequence.
ACCESSION   NZ_AUJG01000024
VERSION     NZ_AUJG01000024
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:55:34
            Original ID  :: NZ_AUJG01000024.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15903
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..156
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="PSSQLCSCCGSRKKLTLQERIYKCKCGLTMDRDLNAAINIKNEGL
                     RLLEVA"
     protocluster    1..15903
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2466:5903]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2467..5903
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..15903
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15903
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1010..2452
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_2"
                     /sec_met_domain="OKR_DC_1_C (E-value: 3e-13, bitscore:
                     40.6, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.3e-128,
                     bitscore: 419.3, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDQTRAPIYEALEKLRRQRVVPFDVPGHKRGRGNPELVELLGER
                     CVGIDVNSMKPLDNLSHPISVIKDAEDLTASAFGAENAFLMVGGTTSAVQAMILSVCKR
                     GDKIILPRNVHKSAINALVLCGAIPVYVNPEVNKDLGISLGMEVSSVEEAIRQNPDAVA
                     VLVNNPTYYGICSDIKSIVKIAHEAGMKVLADEAHGTHLYFQPDLPISGMAAGADMSAI
                     SMHKSGGSLTQSSILLTNKGVNADYVRQIINLTQSTSASYLLLSSLDISRRNLALRGEK
                     SFSKVMEMAEYARKEINSIGGYYAYGKELVNGTSVYDYDVTKLSIHTLGIGLAGIEVYD
                     LLRDEYDIQIEFGDVSNILAYISIGDRLQDIERLVGALADIARIYKKDKTGMLTGEFIS
                     PVVAKSPQEAFYANKISLPLRETKGRISGENVMCYPPGIPILAPGEEITEEIIEYIEYV
                     KEKGCSMQGTEDPEVNNLMVLV"
     CDS             2467..3324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_3"
                     /sec_met_domain="Spermine_synth (E-value: 1.1e-54,
                     bitscore: 175.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 5.2e-16,
                     bitscore: 48.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMWFSELHTSNVKISMRIEKQLFSGVSDCQRIDVLVSDEFGKIL
                     ALDGEILFSEKDEFIYDEMVTHVPMSVHPNVKKVLIIGGGDGGVATALTQYKTIEQIDV
                     VEPDEMFVEVCKEHFPELACGLEDERVNVYIQDALRFLRSKSDEYDLIINDATDPFGYT
                     EGLFTKEFYGNCYKALKEDGIMVYQHGSPFYEEDKEECVKMHRKAYKAFPISRVYQAHI
                     PTCPSGYWLFGFASKKYHPINNFKPAEWKKLGIKTRYYTTNLHKGAFMLPKYVEDMLEE
                     EERD"
     CDS             3343..4602
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.5e-44, bitscore:
                     143.4, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 6.3e-33,
                     bitscore: 104.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLIIGCGGVAQVAITKCCQNSEVFTEICIASRTVSKCEALKE
                     KLEKNTTTKITTAKVDADNVDELVALIESYKPEAVLNLALPYQDLTIMDACLKTKVNYI
                     DTANYEPEDTEDPEWKAIYEKRCKEAGFSAYFDYSWQWAYQDRFKEANILGLLGTGFDP
                     GVTSVFTAYAKKHYFDTIESVDILDCNGGDHGYPFATNFNPEINLREVSAPGSYWEDGH
                     WVEIPAMSIKREYDFPEVGMKDMYLLHHEEIESLAKNYPEIKRIRFFMTFGQSYLTHMK
                     CLENVGMLRTDPVNFNGVDIVPIQFLKELLPDPATLGPRTVGKTNIGCIFKGKKDGKDK
                     TIYIYNVCDHQECYKEVGSQAISYTTGVPAMIGAMMVVTGKWSGTGVFNVEEFDPDPYM
                     EALNKWGLPWVVDENPAIVE"
     CDS             4674..5903
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2e-11, bitscore:
                     34.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIRDLKTPAYVIDENKLEENLKVLESVEKAAGCKILLAQKAFSN
                     FYTYPLISKYISGTTASGIYEARLGKEEMAKENHVFAPAFKDEDMEELVKICDHIVFNS
                     ISQLEHHRPVWQKAGVSVGLRINPEFSTQGDHAIYDPCAPGSRFGVTLKKLEEALEANP
                     RLLDGVDGIHFHTLCEQDSDDLEATLEVVLEKFDFVLKGRKWINFGGGHHITREDYDIE
                     TLIRCINQVKARYNCEVYLEPGEAIALNAGYLVTTVLDKVDNGIETLILDASAACHMPD
                     VLEMPYVPPLKDALKVEDTDLDIWTIKKMYKNGISPVRAMGKQIMEGYSHVYRLSSFTC
                     LAGDIIGDYCFKGEINIGDKLIFEDMAIYSMVKNNTFNGIPLPSIATMKDGDCRIIKEF
                     GYEDFKGRLS"
     CDS             6045..7178
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_6"
                     /sec_met_domain="PAD_porph (E-value: 1.6e-117, bitscore:
                     382.6, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIDNKACMAEYRMPAEYDRHKATIMIWPTRPGSWPNGGVKAKEV
                     FTEIARHIARHEELIMVASKEYEEEAKSYLLSKDNEADSDLINKNIKIVIADTNDAWAR
                     DTSPIFVKKLGDNKAVCGVNFSFNAWGGDYDGLYAHWEEDDKLAINICNELGYDYFDAA
                     PFVLEGGSIHTDGKGTLIATESCLLSPGRNPKLSKQEIEEVLKKTLGMKKIIWIPYGIY
                     NDETNEHVDNVCAFTSEANVVLAWTDKEDDPQYAMSMADLKVLENETDCDGLPLKVHKL
                     YIPDIPVTIKEEDLLGYEFEEGEDERELGERLAASYANFYIANGIALVPKFNDKKDADA
                     IALLQALMPDRKVIGIYARDIIVGGGNIHCITMQIPE"
     CDS             7233..7913
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="LPYYLERCVKTQKDMNKYSKFKVAYCLNICLVVLGIVGLIVSIHS
                     NGLGLFSYYTQDSNILGLLSSLCFVITGYEGFKSGKVKTNNFVSKFRFMATSCMCLTFL
                     VVVFVLIPLAGFKWTGWYLFGGANLYYHTLCPIISFISFTFFEDVVNLRFVNTAINFIP
                     TVIYAAVTITLNALNVMYGPYPFLRVHEQSILASVIWFIVIVGGSWGLSILVYILKKKN
                     LKAA"
     CDS             7935..8819
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_8"
                     /sec_met_domain="CN_hydrolase (E-value: 7e-52, bitscore:
                     166.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKREVKVAAVQFACTRNVDENIATADKYVREAAKAGANIILIPE
                     LFERQYFCQERRYDYYDFATSIEDNKAVNHFIEVAKELSVVVIVSVYEKDITRLFNSVV
                     VIDADGTNLGTYRKTHIPDDHYYQEKFYFTPGDTGFMAFETKFAKIGVGICWDQWFPET
                     ARSMALLGAELLFYPTAIGSEPILELDSMPHWRRVMQGHSAANLMPVIAANRIGREDVT
                     ASEANGGQTSSLNFYGSSFITDNTGEIVEELGRDVEGVICHSFDLDELEKDRVSWGLFR
                     DRRPDMYKIISEK"
     CDS             8829..11459
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MKKLTIGMLAHVDAGKTTLSEAILFKTGVIRKLGRVDNGDAFLDT
                     DEVEKNRGITIYSKEAKFNYKDLEVNLIDTPGHVDFSAEMERNLWALDIAVIVIDQADG
                     VMGHTETVWNLLSKFKIPTFIFVNKMDQAGASKERVLKILQNRLSTNCIDFNKKDMEEI
                     SFASDESLDEYLEAGEVSKETIVSEIYKRHLFPVLFGSALKLEGVEELLDAINDYSKDA
                     YSGKEELDFGARVVKITRENNDRLVHLKLTSGSLQAKDMIGEEKVNQIRVYNGDKFSPA
                     KSVSAGDVCAIVGLNEVTAGQGLGIENLANTAVIAPVLEYKMILPKDKDPLVMLPLLRQ
                     LEEEEPALNIRWNEEFREIIVSLMGAVQLEILTGLIKKRFGVEVSFGTGSVVYKETIKG
                     SSYGIGHFEPLRHYAEVHLKLEEGERGSGLVFKTECSEDLLDKNWQRLVLTHLQERNHK
                     GVLIRANITDMVITLVNGRAHPKHTEGGDFRQATYRAIRQGLMRAESVILEPYYAYEIR
                     LDRAYIGRAMTDIERMGGSSNLIDNGDECLIQGEAPVVAIGNYQAELNTYTKGTGRISL
                     QMAGYKECHNSEEVIETKAYDPERDTRNPVDSVFCAHGSGYTVPWFEVRDHAHCEIIEE
                     NGHTTGDVTLRPINAKAASRTVSDEWIGTEEVDRILSETYYSNSKSDAAKERKRKKNEN
                     NGARYVTAWGDSSKESLYSEKYVGKDLTLYGNKNKEGAKNYLLVDGYNIIHAWPELDEL
                     QKTNFDGARGRLLDIMQHYQSLIHSELIVVFDAYKVKGHQEEFVDLNNIHVVYTKEAET
                     ADHYIEKFAHENGRKRNVTVATSDGVEQVIIRGQGCILMSARELLEDVEKREEELRKNF
                     LNKHF"
     CDS             11516..12973
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="LAIKERFMSKLWVVGDSTLSSFEDKYYYPRYGYGTKLGEYLNDKV
                     EVVNIALSGRSSLSFTKEENYETLMNNMESGDFLLMGFGHNDEKAEVDRFRTAVGDYKT
                     EGSFANSLYVNYIEPARTAGVVPILATPIVRRKTEDNWSKVQLHITEDNGDFKGGDYPE
                     AVRKLAADTHVALVDMTEITRKFYEELGVEETAYLHAWSCNNMVSVDNTHTNVWGAYVN
                     AFFVMKTIKKLGIAGLSENVIDLANYMPYPAKENYLEANKDYKPVEFNSNLEASKLFKD
                     VEGFKVSAFGDILAPADNKDFSCELEEKDGKPAIRMAVRENRGKISIVTDGILFAFKQI
                     PAATKFKLTADITVNDYFSNDQVSFGLMVRDDVYVDMETADVLGDYVAAAPLFLTKKEN
                     ATNCFARRSSEQVLGSKLRREIKKGMTVKACLFATEDGYGASFDDGDVITGGFDFKLTT
                     VDPEHVYLGLFVSRNADVTFSNISLEM"
     CDS             12993..13907
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MKKLLLVFNPNSGKGLIKNSLMQIIQILSEADYEITVYPTKKAND
                     GYEKVLEVGENYDVIVCSGGDGTLNEVVGAILRLENKPQIGYIPSGSTNDFAASLNIDK
                     NMVQAATAIANGNIYPVDIGLVYTDGEYERSFNYVAAFGAFTQVSYNTPQELKNVLGHQ
                     AYVFSGAKELLNLKPQYMQVSGIDENGNEFNIEGNFLYGMVSNTQSVGGMKGIIGNTVD
                     LQDGIFEVLLVKEIKTPLDAQELLGAYITQDYDKCKMVHNLKTSHISFKSDVDVDWTFD
                     GEYGGARKEVTYKVMEAAVDFLI"
ORIGIN
        1 ccatcatcac aactttgtag ctgttgtggt tctcgtaaaa aacttacact tcaagaaaga
       61 atctataagt gtaagtgtgg gcttacaatg gaccgtgacc taaatgcagc tataaacata
      121 aaaaatgaag ggcttagatt gcttgaagta gcctaaactc tgataaatct tatagtaggc
      181 taggaactag ccgaacttat acgcttgtgg acactgtgta agacgttcgt tatccaatag
      241 gatagcctac gcagtggtgg ttgaagcaag aagctccgac ttcaaatacg aagtattaag
      301 tcggagtagt tcacgagata aaatttgaca ctaaaggtaa aatttgctac aatgttgcgc
      361 gtatgagaag taaccctttt catgcaaata tgaccacttt ttaaaactaa tttaaaaagt
      421 taagcctaac ggacaggcgg gtcggttgcc ggtgtggtaa acccacgtta ttgattgagc
      481 aaaagctctg ttttttaagt tgattacttt ataatcggtg ctagttagca catcatcttg
      541 ttaaacggtc aataaagagt aacacgtatt tgcatgtaat gctataggaa ttctctacat
      601 tttataacag actgatattg aggtgattgt gcgtatgcgc ggtcgcctct tttttagtga
      661 ctaaaacttt agtgactaaa actgtgcagc agcacgcttt gcatgctagc atgcaaaagc
      721 ggtgctattg cacagtcaaa cagaaatgag caagtagacg caaggcgtcg gattgtgaat
      781 ttctgcagca tcatgaaagt gcgaagcacg aaatgatgcg taggtcacta aatagtagag
      841 ggatgtgcca aacaaccagc gacaaggcaa agccggagtc gcgtccggcc aaaaaaaaca
      901 gctgcaaggc gaagctactt gcagcgtccg gaccccaaaa cccctccggt tttgcagcgt
      961 ccgataacac aacttaaaaa acagaaatta taaagaggag gcaagtacta tgctagatca
     1021 gacaagagct cctatatatg aggcactaga aaaattaaga cgacaaagag tagttccctt
     1081 tgatgttcct gggcataaac gaggaagagg taacccagaa ctagtagaat tacttggtga
     1141 gcgttgtgtt ggaatagatg taaactccat gaagccacta gataacttaa gtcatccaat
     1201 ctctgtaatc aaagatgcgg aagaccttac ggctagtgct tttggggcag agaatgcatt
     1261 tttaatggta ggtggaacaa cttcagctgt gcaggctatg attctttcag tctgtaagcg
     1321 aggtgataag atcatcttac ctagaaacgt acataagagc gcaattaatg cattagtact
     1381 ttgcggtgcg attccagtgt atgtaaaccc tgaggttaat aaggatttag gcatctctct
     1441 tggaatggaa gtttcaagtg tggaggaagc tataagacag aatcctgacg cagtggcagt
     1501 acttgttaat aacccaactt attacggtat ttgctcagat attaaatcta tagttaagat
     1561 tgctcacgaa gcaggaatga aggtgctagc cgatgaagct cacggtacac atctttattt
     1621 ccagcctgac ctaccaattt caggtatggc agcaggagct gatatgtcag caatttccat
     1681 gcataagtca ggaggaagct taactcagag ttcaatttta cttactaata aaggagttaa
     1741 tgcagactat gtaagacaga ttattaatct aacacagtct acatctgctt catatttatt
     1801 actatcaagc cttgatattt cccgtagaaa tttagccctt cgcggggaga aatcattttc
     1861 aaaggtaatg gaaatggccg aatatgcaag aaaggaaatc aatagcattg gtggctatta
     1921 tgcctatggt aaggaattag ttaacggtac tagcgtatat gattacgatg taacaaagtt
     1981 atcaattcac acattaggta ttggacttgc aggtattgag gtgtatgatt tacttagaga
     2041 cgagtacgat attcagatag aatttggcga tgtaagtaac attttagctt atatctccat
     2101 tggcgataga ttacaagata ttgaaagact tgttggtgcc cttgcagata ttgcaagaat
     2161 ttataagaag gacaagactg gtatgctaac aggtgagttt attagcccag tggttgctaa
     2221 gtcacctcag gaagctttct atgccaacaa gatatctctt ccacttaggg aaactaaggg
     2281 aagaatttct ggtgaaaatg taatgtgtta cccaccagga atcccaatcc ttgcaccagg
     2341 cgaggaaatt acagaagaga ttattgagta tatcgagtat gtaaaggaaa agggatgttc
     2401 tatgcaagga acagaagatc ctgaagttaa taatttaatg gttttggttt aggaaggttt
     2461 taagatatgg aaatgtggtt ttctgaactt cacacatcta atgtgaagat atcaatgaga
     2521 attgaaaagc aactattttc tggagtttca gattgccaaa gaatcgatgt attggtatct
     2581 gatgaatttg gcaagatttt agcactagat ggtgagatac ttttttcaga gaaggatgag
     2641 tttatctatg atgaaatggt aactcacgta cctatgtcgg ttcatccaaa tgttaaaaaa
     2701 gttcttatta ttggtggagg cgatggtggc gttgccacag cccttacaca atataaaaca
     2761 atcgaacaaa tcgatgttgt agagccggat gagatgtttg tggaagtctg taaggaacac
     2821 ttcccagaac ttgcatgtgg cctagaagat gagagagtta atgtctatat tcaggatgct
     2881 cttagatttt taagaagcaa gtcagatgaa tatgacttaa ttataaatga tgcaacagat
     2941 ccttttggtt atacagaagg actcttcact aaggaatttt atggcaactg ctataaggcc
     3001 ttaaaggaag acggtataat ggtttaccag cacggaagtc cattttatga agaagacaag
     3061 gaagaatgtg tgaaaatgca tcgaaaggca tataaggctt ttccaattag tagagtttat
     3121 caagcacata ttccaacatg tccatcaggt tattggttat ttggatttgc atctaaaaaa
     3181 tatcatccaa ttaataactt taagccagca gaatggaaga agcttggtat caagacacgt
     3241 tactacacaa ccaatctaca taaaggcgca tttatgcttc caaaatatgt agaggatatg
     3301 cttgaagaag aagagagaga ctaattttaa ggaggattaa taatgagccg tttattaatt
     3361 attggctgcg gtggcgtagc tcaggttgct attacaaagt gttgtcagaa tagcgaagta
     3421 tttacagaaa tttgtattgc ctcaagaaca gtatctaagt gtgaggcttt aaaggaaaag
     3481 ttagaaaaaa atacaactac aaagattaca actgctaagg tagatgcaga taatgtagat
     3541 gaattagtag cattaattga aagctataag ccagaggctg tacttaacct tgcacttcca
     3601 taccaggatt taactattat ggatgcttgt cttaagacaa aggttaacta tattgataca
     3661 gctaactacg aaccagagga tacagaagat cctgagtgga aggctattta tgaaaagaga
     3721 tgtaaggaag caggattttc tgcttacttt gattactcat ggcagtgggc atatcaggat
     3781 agattcaagg aagctaatat cttaggcctt cttggtactg gttttgaccc aggtgttaca
     3841 tcagtattta cagcttatgc taaaaagcat tacttcgata caatcgaaag tgtagatatc
     3901 cttgattgta acggtggtga tcacggttat ccatttgcta caaactttaa tccagaaatc
     3961 aacctaagag aagtttcagc tccaggttct tactgggaag atggacattg ggtagaaatc
     4021 ccagcaatgt ctattaagag agaatacgat ttcccagaag ttggtatgaa ggatatgtat
     4081 ttacttcacc acgaagaaat cgaatctctt gcaaagaatt atccagagat taagagaatt
     4141 agattcttta tgacatttgg tcagagctac ctaacacata tgaagtgttt agaaaatgta
     4201 ggtatgttaa gaacagatcc agttaacttc aatggagtag atattgttcc aattcagttc
     4261 ttaaaggaat tattaccaga tcctgcaaca cttggcccaa gaacagtagg taagacaaat
     4321 atcggttgta tctttaaggg taagaaggat ggtaaggata agacaattta tatctataat
     4381 gtatgtgatc atcaggaatg ctacaaggaa gtaggctcac aggctatttc ttatacaaca
     4441 ggtgtgccag caatgattgg tgctatgatg gtagttacag gtaagtggag tggaacaggc
     4501 gtatttaacg tagaagaatt tgatccagat ccatacatgg aagcacttaa taagtggggc
     4561 ttaccatggg ttgttgatga gaatccagct attgtagaat aataataaaa ctaattggaa
     4621 actagtagcg tcactaggcg ggcgttacta gtttttttag aagggagtaa gaaatgaaca
     4681 taagagactt aaaaactcca gcttacgtaa tagatgagaa taaattagag gaaaatttaa
     4741 aagtgcttga aagtgttgaa aaggcagcag gatgtaagat tttacttgca caaaaagcct
     4801 tctcaaactt ttacacctac cctttaattt caaaatatat tagtggaact acagctagtg
     4861 gcatttatga agcccgcctt ggaaaggaag agatggctaa ggaaaatcat gtctttgctc
     4921 cagcctttaa ggatgaagac atggaagaac tagttaagat ttgtgatcac atagtcttta
     4981 actcaatttc tcagttagaa caccatagac cagtttggca aaaagcaggt gttagcgtag
     5041 gtttaagaat taatccggaa ttttccacac agggagacca tgcaatttat gacccatgcg
     5101 ctccaggttc tagatttggc gtgactttaa agaaattaga ggaagcacta gaagctaatc
     5161 caaggctact agatggtgtg gatggaatac attttcatac tctttgtgaa caggattcag
     5221 atgaccttga ggccacacta gaagtggttt tagagaagtt tgattttgtc ttaaagggaa
     5281 gaaaatggat aaactttggc ggtggtcatc atataacaag agaggattat gacatcgaga
     5341 ctttaattag atgcataaat caggtgaagg ctagatataa ctgcgaagtt taccttgaac
     5401 caggagaggc cattgccctt aatgcaggtt accttgtaac cactgttctt gataaggtgg
     5461 ataacggcat tgagacacta atccttgatg catcggctgc ttgtcatatg ccagatgtcc
     5521 ttgagatgcc ttatgttcca ccccttaaag atgcgcttaa ggtggaggat actgaccttg
     5581 atatttggac tattaagaaa atgtacaaaa atggcatatc tccagtgaga gccatgggta
     5641 agcaaatcat ggaaggttac agtcatgtct atagactttc aagctttacc tgccttgcag
     5701 gagacattat tggagactac tgctttaagg gtgagataaa tataggagat aagctaatct
     5761 ttgaggatat ggcaatttat tctatggtta agaataatac ctttaatggc attcctcttc
     5821 caagcattgc cactatgaag gacggagatt gtagaataat taaggaattt ggctacgaag
     5881 actttaaggg aagattaagt tagaaaaggt ctataaagct tagatttaag atcatagaaa
     5941 ttttatgaaa ctaaattttc cacaactaaa tagattatga taaaattaat atgcacggtt
     6001 tgtgcatatt aattttttaa tcctatcaca tttatgaggt tataatgaga atagataata
     6061 aagcatgtat ggcagaatat agaatgcctg cagaatatga tagacataag gcaactatta
     6121 tgatttggcc cactagacca ggttcttggc ctaatggtgg tgtaaaggct aaggaagtct
     6181 ttactgaaat tgcaagacat attgcaagac atgaagagct tataatggta gcaagtaagg
     6241 aatatgaaga agaggctaag tcttatcttt tatctaagga taatgaggct gattctgatt
     6301 taataaataa gaacattaag atagtaattg cagatactaa cgatgcttgg gctagagata
     6361 catctccaat ttttgtaaaa aagttgggag acaacaaagc tgtctgtgga gttaactttt
     6421 cctttaatgc ttggggcggg gactatgacg gtttgtatgc ccactgggaa gaggatgata
     6481 agctagctat taacatttgc aatgaattag gatatgacta ctttgatgca gcccctttcg
     6541 tcttagaagg tggctcaatt catacagatg gtaagggtac tttaatagcg acagaaagct
     6601 gcctacttag tcctggtaga aatcctaaat tatctaagca ggaaattgaa gaggtcctta
     6661 aaaagaccct tggtatgaag aagattattt ggattcctta tggaatttat aatgatgaga
     6721 ctaacgagca tgtggacaat gtctgtgcct ttacctcaga agctaatgtg gtattagctt
     6781 ggactgataa agaagacgat ccacagtatg caatgtctat ggcagattta aaggttttag
     6841 aaaatgagac cgattgcgat gggcttcctc taaaggttca taagttatat atcccagata
     6901 ttcctgtaac tattaaggaa gaggatttat taggttatga atttgaagag ggcgaggatg
     6961 aaagagagtt aggcgagaga ttagcagcaa gctatgctaa cttttatatt gccaatggaa
     7021 tcgctttagt tcctaagttt aacgataaga aagatgcaga tgcaatcgct cttttacagg
     7081 cattaatgcc tgatagaaaa gtaataggaa tctatgcaag agatattatt gtgggtggtg
     7141 gcaacatcca ctgtatcaca atgcagattc cagaatagat tagagagtct aagaggactt
     7201 aatagtcaat taaaaaagga aaaatatggg gcttgcccta ttatttagaa aggtgcgtaa
     7261 agactcaaaa agatatgaat aagtatagta aatttaaagt ggcatattgt ttaaacattt
     7321 gcctagttgt attgggaatt gtaggtttaa tcgtaagcat acatagtaac ggacttggat
     7381 tattttcata ttacacacag gatagtaaca tccttggttt actctcaagt ttgtgctttg
     7441 taatcacagg ctatgaaggc tttaagagtg gtaaagtaaa gacaaataac ttcgtttcta
     7501 agtttagatt tatggctaca tcatgtatgt gccttacttt cttagtagtt gtgtttgttt
     7561 taattccact tgcaggattt aagtggacag gctggtattt atttggtggt gctaaccttt
     7621 actaccacac actttgccca atcattagct ttataagctt tacattcttt gaggatgtag
     7681 tgaatttaag atttgtaaat acagcaatta attttatccc aactgtaatt tatgcagcag
     7741 taacaattac tcttaatgcc cttaatgtta tgtatggacc atatccattc ttaagagtgc
     7801 atgaacagtc aattcttgct tcagtgattt ggtttattgt tattgtaggc ggttcatggg
     7861 gattatcgat tttagtttac attttaaaaa agaagaattt aaaggcagcc taaattaaat
     7921 tctaaaggag atttatgaat aaaagagaag taaaggtggc agcagttcag tttgcctgta
     7981 caagaaatgt tgatgaaaat atagctacag ccgataagta cgtgcgagaa gccgctaagg
     8041 ctggggctaa tattatcctt attccggaac tttttgaaag acaatatttt tgtcaggaga
     8101 gaagatacga ttattatgac tttgctacaa gtatagagga taataaggca gtgaatcatt
     8161 ttatagaagt cgctaaggaa ttatcagttg tagtaattgt aagcgtttat gaaaaggata
     8221 taacaagatt atttaatagc gttgtagtta ttgatgctga tggaactaat cttggaacat
     8281 atagaaagac tcatattcca gatgatcatt attatcagga aaaattctac ttcacacctg
     8341 gagacacagg ctttatggcc tttgaaacta aatttgcaaa gataggtgtg ggaatttgtt
     8401 gggatcagtg gttcccagag actgctcgtt ctatggcact tttaggtgca gaacttttat
     8461 tttacccaac agccattggc agtgagccaa tcttagagct agatagtatg ccacactgga
     8521 gaagagttat gcagggccac tcagcagcta atttaatgcc agttattgca gctaatagaa
     8581 ttggacgtga ggatgttact gcaagcgaag ctaacggagg tcagacatca agccttaact
     8641 tctatggttc atcctttatt actgataaca caggtgaaat tgttgaggaa cttggaagag
     8701 atgtggaagg cgtaatctgc cacagctttg atttagacga gttagaaaag gatagagtgt
     8761 catggggcct atttagagat agaagaccag acatgtataa aataatatca gaaaagtagg
     8821 aatagaatat gaagaagctt acgattggaa tgcttgccca tgtagatgct ggaaaaacca
     8881 cactttcaga ggccattctt tttaaaacag gagttatacg taagcttggt agagttgata
     8941 atggtgatgc ctttcttgac acggacgaag tggaaaagaa taggggtatc accatttatt
     9001 ctaaagaagc caagtttaac tataaggacc ttgaagtcaa tttaatagat accccaggac
     9061 acgtggattt tagtgcagag atggagagaa acctatgggc attagatatt gcagttattg
     9121 taatagacca ggcagatggc gttatgggac atacagagac agtttggaat ttgctatcta
     9181 aatttaagat tcctactttt atttttgtga ataaaatgga ccaggcaggg gctagtaaag
     9241 aaagagtctt aaagatttta cagaatagac tttccactaa ctgtattgat tttaataaaa
     9301 aggatatgga ggaaatctcc tttgcatcag atgaaagctt agatgaatat ttggaagctg
     9361 gggaagtttc aaaagaaact attgtgtctg aaatttacaa aagacatctc tttccagtgc
     9421 tttttggttc agcactaaaa ctagagggtg tagaagaatt actggatgca attaatgatt
     9481 atagtaagga tgcttatagc ggcaaggaag agctagactt tggcgctaga gttgtaaaga
     9541 taactagaga aaataacgat agattggtac atttgaaatt aacttctggt agccttcagg
     9601 caaaagacat gattggtgag gagaaggtaa atcaaattag agtctataat ggtgataaat
     9661 ttagccctgc aaaatcggta tctgcaggag atgtctgcgc aatagtgggc ttaaatgaag
     9721 taactgcagg ccaaggtctt ggtattgaaa atctagcaaa taccgcagtg atagcaccag
     9781 tccttgagta taagatgatt ctaccaaagg ataaggatcc attagttatg ctacctctcc
     9841 ttagacagtt agaagaggag gagccagctc taaatattag atggaatgaa gaatttagag
     9901 aaatcattgt aagtctaatg ggtgctgtgc agcttgaaat tctaacagga cttattaaga
     9961 agagatttgg cgtagaggtt tcctttggaa ctggtagtgt ggtttataaa gagactatta
    10021 agggcagcag ctatggtatt ggccactttg agccgttaag acactatgca gaggtacatt
    10081 taaagctaga agaaggcgag cgaggttctg gccttgtatt taaaacagaa tgtagcgaag
    10141 acttacttga taagaactgg caaagactgg ttttgacaca tttgcaggaa agaaatcaca
    10201 aaggcgtctt aattcgcgcc aacataaccg acatggttat aactttagta aatggtagag
    10261 cccaccctaa gcatacagag ggcggcgact ttagacaggc tacctataga gctataagac
    10321 agggccttat gagggcagag tctgtgattt tagagcctta ctatgcctac gagattaggc
    10381 ttgatagagc ctatattggc agggctatga cagatattga gagaatgggc ggcagctcta
    10441 atttaataga taatggagat gagtgcttaa ttcaaggcga ggcgccagta gtagccattg
    10501 gaaattatca ggctgagctt aatacttaca ctaagggcac gggccgcatt agcttacaga
    10561 tggcaggcta taaggagtgc cacaatagtg aggaagtaat tgagactaag gcttatgacc
    10621 ctgaaagaga tacaagaaac cctgtagatt ctgtattttg cgcccatggt tcaggctaca
    10681 ctgtgccatg gtttgaggtt agagaccacg ctcactgtga aattattgaa gaaaatggac
    10741 atacaacagg agatgtaaca cttcgaccaa taaatgctaa agctgcctca agaacagtgt
    10801 ctgatgagtg gattggaacc gaggaagtag atagaatcct atctgaaacc tactactcta
    10861 atagtaagtc agatgctgct aaggaaagaa agagaaagaa aaatgaaaat aatggggcaa
    10921 gatatgtaac tgcctgggga gactcttcta aggagagttt gtattctgag aagtatgtag
    10981 gtaaggactt gactctttat ggtaataaga acaaggaagg tgcaaagaat tacctacttg
    11041 tggatggcta taatattatt catgcatggc cagaacttga tgaattgcaa aagactaatt
    11101 ttgatggggc aaggggtaga ctccttgata ttatgcagca ttatcagtct ctaattcatt
    11161 cagagcttat tgtggttttt gatgcctata aggtaaaggg acatcaagaa gagtttgtag
    11221 atcttaataa cattcatgtg gtttacacta aggaagcgga aactgcagat cattacatag
    11281 aaaaatttgc ccatgaaaat ggcagaaaaa gaaatgtaac agtggcaacc tctgatggag
    11341 tggaacaggt gattattaga ggtcagggat gcattttaat gtctgcaagg gaattgcttg
    11401 aagatgtgga gaagagagaa gaggaacttc gaaagaattt cttaaataaa cacttctaat
    11461 attgataaaa ctttttcaat gtattaatct tataaatgcg caattttaaa ttgctttggc
    11521 aataaaggag agatttatga gtaagttatg ggttgttgga gattctacac ttagtagttt
    11581 tgaagacaag tattattatc caagatatgg atacggaaca aaattgggag aatacctaaa
    11641 tgataaggta gaagtggtaa acattgcact ttcaggtaga agttctcttt cctttactaa
    11701 agaagaaaat tacgaaacat tgatgaataa tatggagtct ggagatttcc tacttatggg
    11761 ctttggccat aatgatgaga aggctgaagt agacagattt agaactgcag tgggagacta
    11821 taagacagaa ggaagttttg caaactcact atatgtaaac tatattgaac ctgcaagaac
    11881 agcaggagtg gtgccaattc ttgctacacc tattgttaga cgtaagactg aggataattg
    11941 gagcaaggtt cagctacata tcactgagga taacggtgat tttaagggtg gcgattatcc
    12001 agaggcagta agaaagctag cagcagatac acatgttgcc ctagttgata tgacagagat
    12061 tacaagaaag ttttatgagg agcttggagt tgaggaaact gcttatcttc acgcttggtc
    12121 ttgtaataac atggtaagtg tagataacac tcacactaat gtatggggcg cctacgtcaa
    12181 tgcatttttt gttatgaaga ctattaagaa gcttggaatt gctggtcttt ctgaaaatgt
    12241 aatagaccta gctaattaca tgccataccc tgctaaggaa aactaccttg aggctaataa
    12301 agattataag ccagtagaat ttaattctaa cttagaggca agtaagctct ttaaggatgt
    12361 agaaggcttt aaggtatcag cttttggtga tattttagct cctgcagata ataaggactt
    12421 tagctgtgag cttgaagaaa aggatggaaa gcctgctatt agaatggcgg taagagagaa
    12481 cagaggtaag attagtattg taacagatgg tatcttattt gcctttaagc agattccagc
    12541 agcaactaaa tttaagctaa cagcagatat aacagttaat gactatttta gtaatgacca
    12601 ggtttccttt ggacttatgg taagggatga tgtctatgtt gatatggaaa cagctgacgt
    12661 attaggagat tatgtggcag cagctccact cttccttact aagaaggaaa atgctacaaa
    12721 ttgctttgca agaagaagta gcgagcaggt tcttggctca aagcttagaa gagaaattaa
    12781 gaaaggtatg acagtgaagg cttgcctttt tgcaacagaa gatggatatg gcgcaagttt
    12841 tgatgatgga gatgttataa ctggcggctt tgactttaag cttacaacag ttgatcctga
    12901 gcatgtatat cttggattat ttgtaagtag aaacgctgat gttacatttt caaatataag
    12961 cttagaaatg tagagaaaca gaggaggata ctatgaagaa gttattattg gtatttaacc
    13021 ctaattcagg aaaaggactt attaagaata gcctaatgca gataattcag attctatcag
    13081 aggcagacta cgagataact gtttacccta caaagaaggc caatgatgga tatgagaagg
    13141 tattagaagt tggtgaaaat tatgatgtca ttgtgtgtag cggtggcgat ggtactttaa
    13201 atgaagtagt aggggcgatt ttgcgtttag agaataagcc tcaaatcgga tatataccaa
    13261 gtggaagtac taatgatttt gctgcaagtc taaatattga taagaacatg gtgcaggcag
    13321 ctactgctat tgctaatggt aatatttacc ctgtagatat tggactagtt tacacagatg
    13381 gagagtatga gaggtccttt aactatgttg cggcctttgg cgcatttaca caggtaagct
    13441 ataatactcc acaggagtta aaaaacgtgt taggtcatca ggcctacgtc ttttctggcg
    13501 caaaggaatt gcttaattta aagccacaat acatgcaggt ttcaggtatt gatgagaatg
    13561 gaaatgaatt taatatagaa ggcaatttcc tatacggcat ggtaagtaat actcagtcag
    13621 taggtggcat gaagggcatt attggtaaca cagtggattt acaggatgga atttttgaag
    13681 ttctacttgt aaaggaaatt aagacaccat tagatgcaca agaactactt ggcgcatata
    13741 ttacacagga ttatgacaag tgtaagatgg tgcacaatct aaagactagc catattagct
    13801 ttaaatctga tgtggacgta gattggacct ttgatgggga atatggcggt gcaagaaaag
    13861 aagttaccta taaggttatg gaagctgctg tagacttctt aatttaaaat agtatatgct
    13921 ttataaaatt aagtaaatta ggcaaaaaca ccttacactt aattttctta agcggacatt
    13981 ttgaaaacta agttaataat ttaaagcgaa aaactcctac aaaagtaaat tgttggaatt
    14041 gtatcttaat attattttga aaaaatttaa agatagccct aaaaagccac tttttaataa
    14101 tttaaagtgc ttttggggct atttttttat gaaatttcac acaatttaga cacaattcgt
    14161 tgcaactaac cagactaatt cttttgaaaa tgtgtattta tcgggaatga attgtctgac
    14221 aatttaattt tacaagtttt ccaaaaagtt ttaagatttc tcacaagcaa gtaaatatgc
    14281 cagttatggc gattggctgt tttagttatg aggaagttac taatagattt gacttgcaat
    14341 ttatctttag gaaagggatt agcttatgga aaaagaaatg agaaaaccag gactatatag
    14401 ggcagacttt gaacatgata actgtggtat tggtgccgta gttaacatca atggtgtgaa
    14461 gacacacaag acagtatctg atgcgttaag tattgtggaa aatttggaac acagagcagg
    14521 taaggatgct aagggagaaa caggagacgg tgtgggaatc cttcttcaga tttctcataa
    14581 atttttcgaa aaggttacaa agaacacagg aatttctatt ggaaaagaaa gagactacgg
    14641 aattggtatg ttcttcttcc ctagagatga atttgcaaga aacagagcca agaagatgtt
    14701 tgagattatt gttgagaagg aaggtatgga attccttggt tggagagaag ttccaacaac
    14761 accatcagtt cttggtaaga aggcaatcga ctgcatgcca tttattgagc aggctttcgt
    14821 taaaagacct aagaaggtaa atcagggtat cgactttgat agaagacttt atgtagcaag
    14881 acgtgtattt gagcagacag cagaggatac ttatgtatgt tcactttcta gtagaacagt
    14941 aatttacaaa ggtatgtttt tagttggtca gttaagaaaa ttctatctcg atttacagga
    15001 tgaagcttac gaatcagcta tcgcccttgt acattcgcgt ttctctacta acacaaatcc
    15061 aagttgggaa agagctcatc ctaatagatt tattgttcac aacggtgaaa ttaatactat
    15121 taagggtaat gcagatagaa tgcttgcaag agaagagaca atggtttctc catacttaga
    15181 agaggaaatg gctaagatca caccagtagt aaatgtaaat ggttcagatt cagctatgct
    15241 tgataatact cttgaattcc ttgttatgaa tggaatgcca cttccacttg ctgttatgat
    15301 tacaattcct gagccatggg ctaagaataa gtctatgagc cagaataaga aggatttcta
    15361 tcaatactat gcaacaatga tggaaccttg ggatggtcct gcatcaatcc tcttctcaga
    15421 tggtgatgta atgggcgcta tccttgatag aaatggtctt agaccttcaa gatactatgt
    15481 aacaaatgat ggttacatca ttctttcatc agaggttggt gtacttgaaa ttgatgagtc
    15541 aagaattgca aagaaggata gacttcgtcc aggtaagatg ctccttgtgg atacaacaaa
    15601 gggcaaggtt atttctgatg atgagttaaa ggaacatttt gcatcagaaa agccttatgg
    15661 cgaatgggtt gattctgagc ttgtttggct tgcagactta aagattccaa acaagaagac
    15721 acctatgcat actaaggaag aaagagcaag acttcaaaag gcctttggtt atacatacga
    15781 agactttaag acttcaattt taccaatggc acttaatggc ggtgaagcaa ctggagctat
    15841 gggtattgat actccacttg cagtactctc aaatcatcat cagccattat ttaactattt
    15901 taa
//
