LOCUS       c00046_NZ_PPTT..       11616 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_PPTT01000050.1 Eggerthella sinensis strain DSM 16107 NODE_50,
            whole genome shotgun sequence.
ACCESSION   NZ_PPTT01000050
VERSION     NZ_PPTT01000050
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:07:19
            Original ID  :: NZ_PPTT01000050.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11616
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11616
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[338:11468]"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      339..11468
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
     cand_cluster    1..11616
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /kind="single"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11616
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /region_number="1"
                     /rules="((DmsC and Molybdopterin and minimum(2, [Fer4_11,
                     Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or (NrfD and
                     Molybdopterin and minimum(2, [Fer4_11, Molybdop_Fe4S4,
                     Molydop_binding]) and not (Nitr_red_bet_C or
                     Nitrate_red_del)))"
                     /tool="gutsmash"
     CDS             complement(2..334)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MKKKNSLRVRFLVMLAVLAVVAVGYFTAGGIGNLCGIGFGDITLL
                     CPLGALLAMLAQKTAIPLAVISVIVVLLICIVLGKVFCAWACPVHFMSRLRKPRHGAAD
                     GLAHAPA"
     CDS             complement(339..980)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="Fer4_6 (E-value: 6.1e-09, bitscore: 25.3,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-05, bitscore: 14.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPEEKRSAPKGASVSRRTFALGAVGACAVVGLGGVKYLPSQTL
                     CRPPGGQDEEQLVAGCVHCEKCREVCPHNAIAPAHIEQGILNARTPRMNFKSGWCDFCE
                     NEPGGPKCIAVCPTHALTEVDPTAVIIGIAELNRDWCLAAKGMGCHECVDVCTYEALEL
                     GYDNVPVVDADACNGCGACELACISLSAGSITTGATDRAIVVKPTEEAGA"
     CDS             complement(980..1705)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="Nitrate_red_del (E-value: 8.7e-34,
                     bitscore: 105.9, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYDITFAEVLRGRMATYQFLSRLFRVEVDQELLDTLMTMKFPA
                     NTGNELVDEGYRLMCSYLGKADAAVLTDLAVDYVRAFIGSGNDGFSAAYPYESVYTSPK
                     RLMMQDARDEVLVLYHAAGLDKQESWKEGEDHIALELEFEQILIERALTALEQGEDETC
                     LNLLLQQRNFLEDHLLAWYPMMAHDLQKFPNTDFYRGLGKLTSGYLRNDFEFLTEVLED
                     NGVLAGDAVEEREVAEGVA"
     CDS             complement(1716..2477)
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MSDIEVFTIDDDFDPLAELSIDEEEVAQETDYLPPIPDAELSVVP
                     PKVELPPAERIAKLIEGIPGQMVRILRTVELCREPRTMSELAAEVDAEFPNEVSVYTAA
                     QLVQLLERAGGVERVEDEAPADAGESLVDADGFIVVTPAPPVRYVATQAGLDAAEARVS
                     EAAIIAMLQEEPQYLPLYERIFSMCSREGGCPVKELDAAIDHDPLCVEPRRFCGYFLGK
                     LERLGALEWNTVWTVSALGTQVMASDIFSRN"
     CDS             complement(2520..4313)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MSACSFSSVDEVTHALLERGDVAKLRIERGASDDLAPAFLAYANQ
                     LNQTGTRARIVCVDDVAAQRFRTSLEAYPALGADAVVTVRELCLSLAADGRVRAAMGRE
                     ARLLNDNEHDVLLEDLKVSGIKPRRLREMLKFFYKSISDCFSEEPGWLVTNEEQMVFAI
                     LEENLDVRRALLPCELPGRVYHGLVDAGAEVEPLVLLVDDFGTLSKAAQRLVQHVAGAG
                     LVVAGASTEARNAEEPYPWIEGFASFADATGADAWTLETGAGAPVGACIVCPDPYAEFA
                     CVADQVKARLDAGMAPHDVLVAVPNGTWAAKMVEALEARGIAAVRDGGAGRLKGDPRYA
                     EKCADLKLAAFLQLILDPHDFTALRSWIGMGDWLLRSDAFLELMAYARDHEMTVPEAVA
                     ALRAMDDEARGMNVFGKFDAPLDELDELRRACEGIGRDEAVLLFERHGMPLAPRMVALL
                     GDDPARADLENLARNAFAGAGTSGGAGADAGADAVSVVPYRSCHGHFARVTFVTGLVNG
                     FLPRLDAVDDKYTIDHRAVALERERVLFDDVCATATDEVVCTRFERDRLENTGVLDMQT
                     ARVFIKNGIRYASVVPSAFVS"
     CDS             complement(4430..5029)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -1.9; E-value: 12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="HTH_1 (E-value: 3.3e-24, bitscore: 74.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METAYLHEYRCVAECGSFTAAARELHLTQSTLSKHVAALEREFGA
                     DLFVRDRSGLKLTAAGEALYAQAGQLEHVLRQTRGLVHAAAAGAAGEGRGERGGRADGA
                     GLAGAASAAGTSVRRAASCDAVLRCKCRMAAERYGLDRQETGALVLYLEERGLKAIQDE
                     LGLSRDNVADVLGRVYRKLGVSGKQEALDIVHSVSE"
     CDS             complement(5035..6531)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MEQLRSTRGSSWGKDLSLKRVIGFSFDRLWMLMAFYSIVPYLYSS
                     DVRGSLYTTLFISLCAMVVTLLFVSVIMRGQDSIAGNRTIVAVAAAVTCVGSLLTPFSD
                     LNTTYGMLILGISSIMTGTGSAVLFLGWIGLFSGVGGRLSLFELSAGMCVAFVVSLVLV
                     AVPPLLANIAVICLPLASGFMLGRLGGAKAPALPLPEQPPSGRTVGLFAKALAGAVLVG
                     MLEGFFDVLSGYRTFEVQDVYGMYLLAAGFFAMLAVVLIAVFLSRDGVFFAYRFAMLLL
                     CLGCLLTPFMGDNNTYSSAIIFGGYNCFTITLCVVCIDVARSFRIGAVRTIGLGLFALC
                     GGEVIGSAMAHGLHIAGFTSFDLAGVTLVAVSALFVAHLFLFTETDLIKLGIGEVSRVL
                     PGADEGVVAEVDESVGEDEDPVDPCDAIVEKFSLSPRESDVLPLLLQGRTISRIQETLF
                     ISAGTVSTHIRHIYQKTGVDNRQELIDLVERTREHAEEVE"
     CDS             6910..9963
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molybdop_Fe4S4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 5.9e-08,
                     bitscore: 22.2, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 2.6e-35, bitscore:
                     111.5, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 5.2e-25,
                     bitscore: 77.1, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTLTMSRRTFVKTAAITGAAAAAFGGSTRVALADQTYSAASGND
                     TVAVKTCCRGCGKMECGVKVIVQNGRAIRVEGDEGAFQSMGNCCTKSQSSIQAAYHPDR
                     LHYPMKRTNPKGEEPGWQRVTWDEAMQSVVDNFMKIKQQYGGEAIACQVGTSRIWCMHS
                     ESILKNMLETPNNVEAWQICKGPRHFATTMVSQFAMSWMETITRPKVYVQWGGASELSN
                     YDDSCRTTVDVASRADVHISVDPRMANMGKEADYWQHLRPGTDGALALAWTNVIIEKKL
                     YDDLYVKKWTNAPFLVCEDIEPSGFPTVRTDGSYWDVKTLLLKESDVKEGGSPYKFLVY
                     DNNWEKLKAEGIEHEYGPFTWFNADQEGNIDDTGGFWEGENYDSEKAREGREANQDNLL
                     PGQTQGWLPDPMPFDPAIDPALDGEFEIELKDGKTYKVKPVWEYYKAQCGKYDLKTAEE
                     ITGIPASEIEAAATTYGTRIDPSTGYGNGGIQYMLAIEHGCNSVQNSRALDNLVGITGN
                     MDTPGGHRGPTIVPIDGDLQGFSAWAPGASTPPAEVNEKQIGIDKFPLISWWQYWCDSH
                     ALWDAVITGDPYPVRALWNESGNFMSQCNTTRAWEALCSLDFYVDLNLWHTPQNDTADI
                     ILPVAHWIELNSPRASQGAAGAMGATVKCIEPPAEAKYDPEIVMDLAKRMNWQWTNEPG
                     NEWPSIDWQLDDSIKLLTDDELTYTTWHVENGKPTFERHGVPMAEVTPKYKTWNEYVEA
                     FQQHGWWQAKDVEPRNWGTYRRYQTGAMRARDRVWARLDYTAGKGIGDWKPGWFTPTMK
                     QEIWSTVMETHHPEHRDWWLPSWDEPPHGPKDGDRIKEYPLTATTGRRIPVYFHSEHRQ
                     LPWCRELWPVPRVEINPKTAAEYGIEQGDWVWIETEWGKIREVADLYYGVKEDVVNLEH
                     TWWYPEVKDAGHGWQHSQVNQLIDHGAQDPHAGSSNLRAYQVKIYKATPENSPFNNPVP
                     CDSTGTPIIHTSDDPRLKEWLPTYEGRE"
     CDS             9967..10599
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="Fer4_2 (E-value: 2.6e-09, bitscore: 26.4,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_11 (E-value: 2.4e-27, bitscore: 84.5,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 19.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKAIITDLNRCVGCLACSVACKGVNNVPIGSYWNKVVRVGPNPI
                     PGGSGQYPDVYMYFLPISCQHCENPECVKVCPTEASHVAEDGSIQIDKEKCIGCQFCVM
                     ACPYGVRYLNEEEKVVEKCTLCEQKLQQGELPQCVSQCGGNARWIGDTEDGLESFEGSE
                     DPLGNRRKMVDFLEPFTEADMHKLPDVGNKPSYSYILRGQHWEGGDE"
     CDS             10599..11468
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: DmsC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_10"
                     /sec_met_domain="DmsC (E-value: 6.4e-11, bitscore: 31.5,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METQWPLVIFTLFVCLTSGILGGMSILALKGEGKTLQMTALITSA
                     VSLVVGGLGAFLHLQHWERIFNGFGHITSGITQELIGCVALAIIIVIWFVMLRGDKPVS
                     KALAWVTIVVAACMVIATAHSYLMPARPAWGLALIAFYLGNACILGAVAIWLIAILKKD
                     EAAERTGIQLTFIASIVQLVGDAVFVAACGMASIAQFGYYADPTSMTTAPVHIDSLLTV
                     MMTGEGALMFWGSIICAVIALVCALVAKKKVGDSKVYMVVAAIVILAASVMFRVLIYQL
                     GYPMVLLY"
ORIGIN
        1 gggcgggggc atgggcgagg ccatccgcgg cgccatggcg gggtttcctc agccgcgaca
       61 tgaaatgcac ggggcaggcc caggcgcaga acaccttgcc cagcacgatg cagatcagca
      121 gcaccacgat cacgcttatc acggccaggg ggatggcggt tttctgggcg agcatggcca
      181 gcagcgcgcc gagggggcac agcagcgtga tgtcgccgaa gccgataccg cagaggttgc
      241 cgatgccgcc ggccgtgaag tagcccacgg ccacgaccgc cagcacggca agcatcacga
      301 gaaaccgaac ccgcaggctg tttttcttct tcatgcgatc acgctcccgc ttcttcggtg
      361 ggtttcacca cgatggcgcg atcggttgcg cccgtggtga tagagccggc cgacagcgag
      421 atgcaggcca gctcgcaggc accgcatccg ttgcacgcgt cggcatccac caccggtacg
      481 ttgtcgtagc ccagctcaag cgcctcgtag gtgcacacgt ccacgcactc gtggcacccc
      541 atgcccttcg ccgccaggca ccagtcgcga ttgagctccg cgatgccgat gatcaccgcg
      601 gtcgggtcga cctcggtcag cgcatgggtc gggcacacgg caatgcactt cgggccgccg
      661 ggctcgttct cgcagaagtc gcaccacccg ctcttgaagt tcatacgcgg cgtgcgcgcg
      721 ttcagaatgc cctgctcgat atgcgcgggc gcgatggcgt tgtgcgggca cacctcgcgg
      781 cacttctcgc agtgcacgca ccctgccacc agctgctctt cgtcctgacc tcccggcggg
      841 cgacacaacg tctggctcgg caggtacttc acgccgccca ggcccaccac cgcgcacgcg
      901 cccacggcgc cgagcgcgaa cgtacggcgc gaaaccgacg cccccttcgg cgcgctcctc
      961 ttttcctcgg gctcgctcat tacgccacgc cctctgcaac ctcgcgctcc tcgacggcgt
     1021 cgccagccag cacgccgtta tcctcaagca cctcggtgag gaactcgaaa tcgttgcgca
     1081 aatacccgct ggtcagcttg cccaaaccgc gatagaagtc agtgttcggg aacttctgca
     1141 aatcgtgcgc catcatggga taccacgcca gcagatgatc ttccaggaag ttgcgctgct
     1201 gcagcagcag gttcaggcac gtctcgtcct cgccctgctc gagcgccgtc aaggcgcgct
     1261 cgatgagaat ctgctcgaac tccagctcga gcgcgatgtg atcctcgcct tccttccagc
     1321 tctcctgctt gtccaacccg gcggcgtggt acagcacgag cacctcgtcg cgcgcgtcct
     1381 gcatcatgag gcgcttcggg ctcgtgtaca ccgactcgta cgggtaggcc gccgagaagc
     1441 cgtcgttgcc cgacccgatg aacgcgcgca cgtagtccac ggcgaggtcg gtgagcacgg
     1501 cggcatcggc cttgcccaga tagctgcaca tgagacggta gccctcgtcc accagctcgt
     1561 tgcccgtgtt cgccgggaac ttcatggtca tgagcgtgtc gagcagctcc tgatcgacct
     1621 cgacgcggaa cagccgcgac aggaactggt aggttgccat gcggccgcgc agaacttcgg
     1681 cgaaggtgat gtcgtattca gtcatgatgg gctccttagt tgcgagagaa gatgtcggat
     1741 gccataacct gagtccccaa agcggagacg gtccacacgg tgttccattc cagggcgccc
     1801 aagcgctcga gcttgcccag gaagtagccg cagaaacggc gcggctccac gcacagcgga
     1861 tcgtggtcga tggcggcgtc gagctctttc accgggcagc cgccctcgcg cgagcacatc
     1921 gagaagatgc gctcgtacag cggcaggtac tgcggctcct cctgcagcat ggcaatgatg
     1981 gccgcctccg acacgcgcgc ctccgcggcg tcgaggccgg cctgcgtggc cacgtagcgc
     2041 accggcggcg ccggcgtcac cactatgaag ccgtctgcgt ccacaaggga ctcgcccgcg
     2101 tcggccggtg cctcgtcctc gacgcgctcc acgccgccgg cgcgctcgag cagctgcacg
     2161 agctgcgccg ccgtgtacac gctcacctcg ttcgggaatt ccgcatccac ctcggcggca
     2221 agctcgctca tggtgcgcgg ctcgcggcac agctccacgg tgcgcaggat gcgcaccatc
     2281 tgcccgggaa tgccctcgat cagcttcgcg atgcgctcgg cgggcggcag ctccaccttc
     2341 ggcggcacca cgctcagctc ggcgtcggga atgggcggca ggtagtcggt ttcctgcgcc
     2401 acctcctcct cgtcgatgct gagctctgcc agggggtcga aatcatcgtc gatggtgaac
     2461 acttcgatat cgctcatggg tagatccttt caggaaggga gaaaacgggg aacggggcgc
     2521 taggacacga acgcggaagg taccacggat gcgtagcgga tgccgttctt gatgaacacg
     2581 cgggcggttt gcatgtcgag gacgccggtg ttttccaggc ggtcgcgttc gaagcgcgtg
     2641 cacaccacct cgtcggtcgc cgtcgcgcac acgtcgtcga acagcacgcg ctcgcgctcg
     2701 agcgccaccg cgcgatggtc gatggtgtac ttgtcgtcca ccgcgtcgag gcgcggcagg
     2761 aaaccgttca cgagccccgt gacgaacgtg acgcgcgcga aatgcccatg gcagctgcgg
     2821 tacggcacca cggacacggc atcggcaccg gcatcggccc cggcaccccc gctcgtgccc
     2881 gcccccgcaa acgcgttgcg cgcgaggttc tcgaggtcgg cgcgcgcggg atcgtcgccc
     2941 agcagcgcca ccatacgcgg cgcgagcggc atgccgtgac gctcgaacag cagcacggcc
     3001 tcgtcgcgac cgatgccctc gcaggcgcgg cgcagctcgt cgagctcgtc gagcggtgcg
     3061 tcgaacttgc cgaagacgtt catgccgcgc gcctcgtcgt ccatcgcgcg cagcgccgcc
     3121 accgcctcgg gcaccgtcat ctcgtgatcg cgcgcatagg ccatgagctc gaggaacgcg
     3181 tcggaacgca gcagccagtc gcccatgcca atccaggagc gcagcgccgt gaagtcatga
     3241 gggtcgagga tgagctgcaa gaacgcggcc agcttgaggt cggcgcactt ctcggcgtag
     3301 cgcgggtcgc ccttgaggcg cccggcgccc ccgtcgcgca ccgcggcgat gccgcgcgcc
     3361 tcaagcgcct cgaccatctt cgctgcccac gtgccgttcg gcacggccac cagcacgtcg
     3421 tgcggcgcca tgcccgcgtc cagccgcgct ttcacctgat cggccacgca cgcgaactcc
     3481 gcatagggat cggggcagac gatgcacgcg cccaccggcg cgcccgcgcc cgtctcgagc
     3541 gtccaggcat cggcaccggt cgcgtccgcg aacgaggcga acccttcgat ccacgggtag
     3601 ggctcctcgg cgttgcgcgc ctcggtcgaa gcgcccgcca ccacgagccc cgcgccggca
     3661 acgtgctgca cgagccgctg cgccgccttg ctcagcgtgc cgaagtcgtc caccagcagc
     3721 acgagcggct caacctccgc acccgcatcc accagaccgt ggtacacccg acccggcagc
     3781 tcgcacggca acagcgcccg gcgcacgtca agattctcct cgaggatggc gaataccatc
     3841 tgctcttcgt tcgtgacgag ccagcccggc tcttcgctga agcaatcgct tatgctcttg
     3901 tagaagaact tgagcatctc gcgcaggcgg cgcggcttga tgccgctcac cttgaggtct
     3961 tccagcagca cgtcgtgctc gttgtcgttg agcagacgcg cctcgcggcc catcgcggca
     4021 cgcacgcgcc cgtccgcggc aagcgatagg cacagctcgc gcacggtcac caccgcgtcg
     4081 gcgccgagcg ccgggtaggc ctcaagcgac gtgcggaagc gctgcgcggc gacgtcgtcc
     4141 acgcacacga tgcgcgcacg ggttcccgtt tggttcaact gattcgcgta tgccagaaag
     4201 gcaggtgcaa gatcgtcgga cgcaccgcgc tcgatgcgca gcttcgcgac atcgcctcgc
     4261 tccagcaagg catgcgtcac ctcgtccacc gacgaaaaag aacaagcact catgttcggc
     4321 ctccatccaa atgttcggat gaaaccctct gcctgaagcc ccccagcttc atcaagtgct
     4381 ttcaactatc ggaggtcagt atgcccgacc tctcgcgggg aatctaccat cattccgaaa
     4441 cggaatggac gatgtcgagc gcctcctgct tgccgctcac gcccagcttg cggtacacgc
     4501 gccccagcac gtcggccacg ttgtcgcgcg aaagccccag ctcgtcctga atggccttca
     4561 acccgcgttc ctccaggtag agcacgagcg cgcccgtctc ctgccgatcc aagccgtagc
     4621 gctcggcggc catccggcac ttgcagcgca gcacggcatc gcacgatgcc gcgcgccgca
     4681 cgctcgttcc cgcagccgac gccgcacctg ccaagcccgc cccgtccgca cgtcctccgc
     4741 gctcgccgcg cccctcgccc gccgcgcccg ctgccgccgc gtgcaccagc ccgcgcgtct
     4801 gccgcagcac gtgttccagc tgcccggcct gcgcgtacag cgcctcgccc gccgccgtga
     4861 gcttcaggcc actccggtcg cgcacgaaca ggtcggctcc gaactcgcgc tcgagggcgg
     4921 ccacatgctt gctcagcgtc gactgcgtga ggtgcagctc gcgcgcagcg gccgtgaagc
     4981 tgccgcactc ggccacgcac cggtattcgt gcaggtaggc ggtttccatc gcggctattc
     5041 gacctcttcc gcatgctcac gcgtgcgctc cacgaggtcg atgagctcct gacggttgtc
     5101 cacgcccgtc ttctggtaga tatggcggat gtgcgtgctc accgtgcccg ccgagatgaa
     5161 cagcgtttcc tgaatgcgcg agatggtacg gccctgcagc agcagcggca gcacgtcgct
     5221 ttcgcgcggc gacaggctga acttctccac gatggcgtcg cacgggtcca cggggtcctc
     5281 gtcctccccc acgctctcgt cgacttccgc caccacgccc tcgtccgcac ccggcagcac
     5341 ccgactcacc tcgccgatgc ccaacttgat gaggtcggtc tcggtgaaca ggaacaggtg
     5401 cgccacgaac agcgccgata cggccaccaa cgtgacaccg gccaggtcga acgacgtgaa
     5461 ccccgcaatg tgcagcccat gcgccatggc cgagccaatc acctcgccgc cgcacagcgc
     5521 gaacagcccc aacccgatgg tgcgcaccgc gccgatgcgg aagctcctgg ccacatcgat
     5581 gcagaccacg cacaaggtga tggtgaagca gttgtaaccg ccgaagatga ttgcgctcga
     5641 ataggtgttg ttgtctccca tgaacggcgt gagcaggcag cccaagcaca gcagcaacat
     5701 ggcgaagcgg tacgcgaaga acacgccgtc gcgggacagg aacacggcga tgagcaccac
     5761 cgcgagcatg gcgaagaagc ccgccgccag cagatacatc ccgtagacgt cctgcacctc
     5821 gaacgtgcgg taccccgaca gcacatcgaa gaagccttcg agcatcccca cgagcaccgc
     5881 acccgccaac gccttcgcga acagccccac ggtgcgtccc gacggcggct gctcgggcag
     5941 cggcaacgcc ggcgccttcg cgccgcccaa ccggcccagc atgaagcccg acgccaaggg
     6001 caggcagatc accgcgatgt tcgccagcaa gggcggcacg gccaccagca cgagcgacac
     6061 gacgaacgcg acgcacatgc ccgccgacag ctcgaacagc gacaagcgcc ctcccacgcc
     6121 cgagaacaga ccgatccatc cgaggaacag cacggccgaa ccggtgccgg tcataatgct
     6181 gctgatgccc aggatgagca tgccgtacgt ggtattgagg tcggagaagg gcgtcagcag
     6241 gctgcccacg caggtgaccg ccgccgcaac cgccacgatg gtgcggttgc cggcaatgct
     6301 gtcctgtcct cgcatgatca ccgacacgaa cagcagcgtg accaccatcg cgcacagcga
     6361 tatgaacaag gtggtgtaca gcgagccgcg cacgtcggac gagtacagat acggaacgat
     6421 gctgtagaac gccatgagca tccacaggcg atcgaacgag aatccgatga cgcgcttgag
     6481 cgagaggtcc ttgccccacg aagatccccg cgttgatcga agctgttcca tgctcatgct
     6541 ccccccgccc gtcgagccgt gcaatcatgc ttccgccgat ccctcaatcg gcagatctga
     6601 ttatacgtat aacgataatg attaccgcgc tctactttat actagtttca gtataattca
     6661 tgatgcatcc gcaccatttt acctggtcat caccgtctgc atgtttctca tgatctgaaa
     6721 atcataagaa tttatgatgc gccgttcccg gcctcgcaac gtttcgacga tgctcgcatg
     6781 cccctcgctt ccgtatggtc accgtgcgaa ccggggaact ctgcaccgca caagcggaaa
     6841 cccccttccc cgatcgccag acgagagcag taccgaacga gacgagattt gaggagaagg
     6901 aggaggagta tgggaaccct gactatgtca cgacgcacgt tcgtcaagac cgcagccatc
     6961 acgggcgccg cagctgccgc attcggcggc tcgacgcgcg tcgcgctggc cgatcaaacg
     7021 tacagcgcag cgtccggcaa cgacaccgtc gccgtgaaaa cctgctgccg cggctgcggc
     7081 aagatggagt gcggcgtcaa ggtcatcgtg cagaacgggc gcgctatccg cgtcgaaggt
     7141 gacgagggtg cgttccagtc catgggcaac tgctgcacga agtcgcagtc gtccatccag
     7201 gcggcgtatc atcccgaccg tctgcactac cccatgaagc gcacgaaccc gaagggcgaa
     7261 gagcccggct ggcagcgcgt cacgtgggac gaggccatgc agtcggtcgt cgacaacttc
     7321 atgaagatca agcagcagta cggcggcgag gccatcgcct gccaggtggg cacgtcgcgc
     7381 atctggtgca tgcactcgga gtccatcctg aagaacatgc tcgagacgcc gaacaacgtg
     7441 gaagcctggc agatctgcaa gggcccgcgc cacttcgcca ccaccatggt gtcgcagttc
     7501 gccatgtcgt ggatggaaac catcacgcgt ccgaaggtat acgtgcagtg gggcggcgct
     7561 tccgagctgt ccaactacga cgactcctgc cgcaccacgg tggacgtcgc gtcgcgcgcc
     7621 gacgtgcaca tcagcgtcga cccgcgtatg gccaacatgg gcaaggaagc cgactactgg
     7681 cagcacctgc gccccggcac cgacggcgcc ctggccctgg cctggacgaa cgtcatcatc
     7741 gagaagaagc tctacgacga cctgtacgtc aagaagtgga cgaacgctcc gttcctcgtg
     7801 tgcgaggaca tcgagccctc cggcttcccc accgtccgta ccgacggttc gtactgggac
     7861 gtgaagacgc tcctgctcaa ggaaagcgac gtcaaagagg gcggcagccc ctacaagttc
     7921 ctcgtgtacg acaacaactg ggaaaagctc aaggccgaag gtatcgagca cgagtacggc
     7981 ccgttcacct ggttcaacgc tgaccaggaa ggcaacatcg acgacacggg cggcttctgg
     8041 gaaggcgaga actacgactc cgagaaggcg cgcgaaggcc gcgaggccaa ccaggacaac
     8101 ctcctgcccg gccagacgca gggttggctg cccgatccca tgccgttcga ccccgccatc
     8161 gaccccgccc tcgacggcga gttcgagatc gagctcaagg acggcaagac gtacaaggtc
     8221 aagccggtgt gggagtacta caaggcccag tgcggcaagt acgacctgaa gaccgccgag
     8281 gagatcaccg gcatccccgc ctccgagatc gaagccgctg ccaccaccta cggcacgcgc
     8341 atcgacccga gcaccggcta cggcaacggc ggcatccagt acatgctggc catcgagcac
     8401 ggctgcaact ccgtgcagaa ctcccgcgcg ctcgacaacc tcgtgggcat cacgggcaac
     8461 atggacaccc cgggcggcca ccgcggcccc accatcgtgc ccatcgacgg cgacctccag
     8521 ggcttcagcg cctgggcgcc gggcgcttcc accccgccgg cggaagtcaa cgagaagcag
     8581 atcggcatcg acaagttccc gctcatcagc tggtggcagt actggtgcga cagccatgcg
     8641 ctgtgggacg ccgtcatcac gggcgacccc tacccggtgc gcgccctgtg gaacgagtcc
     8701 ggcaacttca tgagccagtg caacacgacc cgcgcctggg aagccctgtg ctcgctcgac
     8761 ttctacgtgg acctcaacct gtggcacacg ccgcagaacg acacggccga catcatcctg
     8821 ccggttgcgc actggatcga gctcaactcg ccgcgcgcca gccaaggtgc cgccggcgcc
     8881 atgggcgcca cggtgaagtg catcgagccg cccgcggaag ccaagtacga ccccgagatc
     8941 gtcatggacc tggccaagcg catgaattgg cagtggacga acgagccggg caacgagtgg
     9001 ccctccatcg attggcagct ggacgactcc atcaagctgc tcaccgacga cgagctcacc
     9061 tacaccacgt ggcacgtcga gaacggcaag cccacgttcg agcgccacgg cgtgcccatg
     9121 gccgaagtga cgccgaagta caagacgtgg aacgagtacg tggaagcctt ccagcagcac
     9181 ggctggtggc aggcgaagga cgtcgagccg cgcaactggg gcacgtaccg ccgctaccag
     9241 accggcgcga tgcgcgcacg cgaccgcgtg tgggcccgcc tcgactacac ggccggcaag
     9301 ggcatcggcg actggaagcc gggctggttc acgccgacga tgaagcagga aatctggtcc
     9361 accgtcatgg aaacgcacca tcccgagcac cgcgactggt ggctgcccag ctgggacgag
     9421 ccgcctcatg gcccgaagga cggcgaccgc atcaaggagt acccgctgac cgccaccacc
     9481 ggccgtcgta ttcccgtgta cttccactcc gagcaccgtc agcttccctg gtgccgcgag
     9541 ctgtggcccg tgccgcgcgt ggaaatcaac ccgaagacgg ctgccgagta cggcatcgag
     9601 cagggcgact gggtgtggat cgaaaccgag tggggcaaga tccgcgaagt ggccgacctg
     9661 tactacggcg tgaaggaaga cgttgtcaac ctcgagcaca cctggtggta ccccgaggtg
     9721 aaagacgccg gccacggttg gcagcactcg caggtcaacc agcttatcga ccacggcgcg
     9781 caagacccgc acgccggtag ctccaacctg cgcgcctacc aggtgaagat ctacaaggcc
     9841 acgcccgaga actcgccgtt caacaaccct gtgccgtgcg acagcaccgg caccccgatc
     9901 atccatacct ccgacgaccc ccgtctgaag gaatggttgc cgacctacga agggagggag
     9961 taaaccatga cgaaggctat catcaccgac ctcaaccgtt gcgtgggctg cctcgcgtgt
    10021 tcggttgcct gcaaaggcgt gaacaacgtg cccatcggca gctactggaa caaggttgtc
    10081 cgtgtgggac cgaaccccat ccccggcggt tcgggacagt atcccgacgt gtacatgtac
    10141 ttcctgccca tcagctgcca gcactgcgag aaccccgagt gcgtgaaggt gtgcccgacc
    10201 gaggcgtcgc acgttgccga ggacggctcc atccagattg acaaagagaa gtgcatcggc
    10261 tgccagttct gcgtcatggc ctgcccctac ggcgttcgct acctcaacga ggaagagaag
    10321 gtcgtggaga agtgcacgct gtgcgagcag aagctgcagc agggcgagct gccccagtgc
    10381 gtcagccagt gcggcggcaa cgcccgctgg atcggcgata ccgaggacgg ccttgagtcc
    10441 ttcgagggct cggaagaccc gctgggcaac cgccgcaaga tggtcgactt ccttgagccc
    10501 tttaccgaag ccgacatgca caagcttccc gacgtgggca acaagccgtc gtactcgtac
    10561 atcttgcgtg gacagcactg ggaaggaggt gatgagtaat ggaaactcag tggcctctcg
    10621 tcatcttcac gctgttcgtg tgcctgacca gcggcatcct gggtggcatg tccatcctgg
    10681 cgctcaaagg cgaaggtaag accctgcaga tgaccgcgct catcacgtcc gccgtgtccc
    10741 tcgtggtggg cggcctggga gccttcctgc acctccagca ctgggagcgc atcttcaacg
    10801 gcttcgggca catcacgtcc ggcatcaccc aggagctcat cggctgcgtg gcgctggcta
    10861 tcatcatcgt catctggttc gtgatgctcc gcggcgacaa gccggtttcc aaggcgctcg
    10921 cctgggtgac catcgtggtg gccgcgtgca tggttatcgc gacggcgcac tcctacctca
    10981 tgccggcccg tccggcttgg ggcctggcgc tcatcgcgtt ctacctgggc aatgcctgca
    11041 tcttgggcgc cgtggccatc tggctcatcg ccatcctcaa gaaggacgag gcggccgagc
    11101 gcacgggcat ccagctgacg ttcatcgcct ccatcgtgca gctcgtgggc gacgcggtgt
    11161 tcgtggcagc ctgcggcatg gcgagcatcg cgcagttcgg ctactacgcc gacccgacgt
    11221 cgatgaccac cgctcccgtg cacatcgaca gcctgctcac cgtcatgatg acgggcgaag
    11281 gcgccctgat gttctggggt tccatcatct gcgccgtcat cgcgctggta tgcgccctcg
    11341 tggccaagaa gaaggtgggc gactcgaagg tgtacatggt ggttgccgcc atcgtcatcc
    11401 tggccgcgtc cgtgatgttc cgcgtcctga tctaccagct gggctacccc atggtcctgc
    11461 tgtactagca ccgcaccgct gatcgcgttc cggggaggaa actgcaacct ccccggaacc
    11521 gatcgaggtg agcgggacgc ggctcccctc ctccgtcccg ctcacctcga tcgtgcgccg
    11581 cccaatccct ccccccgtgg caccgcagat cgaccc
//
