LOCUS       NZ_AP021898.1          23579 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP021898.1 Akkermansia muciniphila strain JCM 30893 chromosome,
            complete genome.
ACCESSION   NZ_AP021898
VERSION     NZ_AP021898.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:17:24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1050837
            Orig. end    :: 1074416
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23579
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1060837:1064416](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13579)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..23579
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23579
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="PFOR_II_pathway"
                     /region_number="4"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(2841..3545)
                     /locus_tag="ctg1_897"
                     /transl_table=11
                     /translation="MRYTVIGLGQFGQELCTELSARNIEVVAVASTDEELEQIKDLVTY
                     AVVTDYTNPAALRELELDDQSAVIVAIGDSFEENLLVVTHLQKMGVRYIYARVMSPVHE
                     HILSQMNVYALINLSRVASKQLASQLESPEFLRVSPMDENHSIVEIAVPRIWVGKRLRD
                     VGLRTEHHLNLLTIRRGEAQTPQGRREILSIPRIPVIGTPSPDLVFEDHDILVLFGKET
                     NLIEFAQLSKGL"
     CDS             complement(3556..5304)
                     /locus_tag="ctg1_898"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLV
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEDNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLAGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             complement(5358..5558)
                     /locus_tag="ctg1_899"
                     /transl_table=11
                     /translation="MPFDKHVPFLTKALFGSVSIPHIHSKRNLLKFINITIPLTFRPAL
                     PRHEETQCGICPFPARMHKTA"
     CDS             5618..6385
                     /locus_tag="ctg1_900"
                     /transl_table=11
                     /translation="VLAKRIIPCLDVTDGRVVKGTNFINLRDAGDPVECARAYDAQQAD
                     ELVFLDITASSDGRATMADVVRRTAACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNT
                     AAINRPELINEGAAAFGSQCIVVAIDAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAER
                     RGAGEILLTSMDADGAKTGYDIELTRAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADA
                     VLAASIFHFGEYTVPEAKAYFASRGIPVRPLAE"
     CDS             6433..8571
                     /locus_tag="ctg1_901"
                     /transl_table=11
                     /translation="MRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPALVSAGTPGDAG
                     NLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGKPRTLSSLHVW
                     PYWEGGRIYKYKIEGSEDGKNWKMLVDQSSNSIAATPEGVPFKFNPQTVRYVKITFLGN
                     SAGNEKGGHLVEIKGYGPDAALSLQAAAVKDYDRIPYNGAPGQEMLQDAVRLSGWRGER
                     AGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLISDIIGSENSCD
                     LQAGGVRPVWVEVNIPPSAKPGVYKGKVVVSAESGSPVSVPVILEVAPESLPAPAHWQA
                     HLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLIDEAWNAQTYDW
                     FPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNMKIRYLDEATG
                     KYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSKGWLGKTCIGLDERPDAMVRAAKNVLDK
                     YAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKTTFYVCVHPKK
                     PNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWPAGDCYLVYPG
                     NLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFTVEKSRGDSHE
                     EDVRKAREIIRKTTEISR"
     CDS             complement(8653..8973)
                     /locus_tag="ctg1_902"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPILASMAEWGSKYQRE
                     NR"
     CDS             9098..9535
                     /locus_tag="ctg1_903"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             complement(10001..13579)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_904"
                     /sec_met_domain="PFOR_II (E-value: 7.9e-16, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6e-77, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.2e-30, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.6e-10, bitscore:
                     36.1, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.4e-11, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.5e-08, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0005, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4e-24, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATNGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             13642..13878
                     /locus_tag="ctg1_905"
                     /transl_table=11
                     /translation="MSGAKGKSNYAYVGLCRPFFNNKTSFVSIPLDIVLYVVLSKLFAK
                     RPEYWGMFRHPASEKGGEGTFGSKPAAKNVPSA"
     CDS             13925..15406
                     /locus_tag="ctg1_906"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWKRADYQDLIRGVAGEDWFDIS
                     PEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             15424..16209
                     /locus_tag="ctg1_907"
                     /transl_table=11
                     /translation="MAPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAVVFAESGIEDIPERLTAALHAANRALAAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADCLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             16462..17106
                     /locus_tag="ctg1_908"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             17111..18118
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_909"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 2.1e-41,
                     bitscore: 138.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLASNIHPTCDLGQVKDAELIVVVVPSVAMRSVAQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASLIGFEDPKYA
                     DWVQQIFASKTFRVYSATDIIGMQLGGTIKNVFAIGAGLCEGLNLGDNAQAALLTRGLA
                     EMTRIGVASGGRRETFMGLSGVGDLIVTCYSRHSRNQTVGRRLAEGKSLQEILDTLGMV
                     AEGVPNTLSVYEIARKLEVRTPLIDAVYSVLYESKPPMEALAELMTRDPRPELD"
     CDS             18176..18610
                     /locus_tag="ctg1_910"
                     /transl_table=11
                     /translation="MKRAIISALFAAGVVGVASADIQAPPASEYTPTRKLGRAIANLIY
                     SVEEIPLGIINWTSREGDYAGFSVGIVDGTATMFERMGYGIYELVTFWAPTYKCTYKPP
                     YQGRCGMSGLKEYNPNGGLSEFPAELSFQSYYKYSRQQRD"
     CDS             18751..19569
                     /locus_tag="ctg1_911"
                     /transl_table=11
                     /translation="MNKIVASISLGTAVCITASAFAQDSHLSLTRQSVASMHEIAAALD
                     KVTDEPGAAAAVETVKKVHKKLLDIGKRQLELPGATLQEQAQVSAQITEAQKISGELIK
                     SLSRLKKEGLLTPDLQKALADLQSVQKELAQASRDKAEQAEPFPEDAEGNTHETLLTKT
                     VEEVKKLNDSLARVRDEETGKAAVEQIGRYRAAMLDVARKQAALPPLTRNQQAKLMGVQ
                     QQLVEMMQPIVKHVTAIMLSPDASRNLKEALNSLSELPKEVQKIREEAAK"
     CDS             19641..20702
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_912"
                     /sec_met_domain="Radical_SAM (E-value: 3.6e-21, bitscore:
                     73.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPVFSETDLNERPFLVFWEVTRACALACRHCRAVAQPRPHPDEL
                     THEEALRLIDQLAELRPPMLVLTGGDPVMRPDILELVRAASGKGLHVALSPAATARLLH
                     TDFHALKEAGVQSMSLSLDGAHESTHDAFRGVPHTYERTLRAAEMAKEAGMHLQINTTI
                     TRSTLGEFDDFVELMKKMKPGMWSVFLLVPTGRAAMDEMPAAEEVEAVWKKLSRISHEV
                     SFGVKTTEGHHYRRVALQEARAQGSKPARRAIPTRDGKGIMFISHTGEIQPSGFLPITA
                     GNVRTDDPGEIYRTHPLFLKLRDDNALQGKCGRCEYRTICGGSRSRAYAVYGDMMAEDN
                     LCPYQPRLSQHHD"
     CDS             20695..21942
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_913"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-25, bitscore:
                     87.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINITRLWTGAEQPADHLRYGQGHGHGRFAGGAVESCAPASSRAR
                     KPIVVWNITRTCNLKCVHCYADASARKFKGELDWDQCCAVIDDLADYKVNALLFSGGEP
                     LVHPRFMELLERATGKGLKVTISTNGTRITPEAAARFKELGVAYVGISLDGIGAVHDKF
                     RGVEGSFEQAVRGFRLCSEVGQKTGLRLTLTRNNVQCMGQILDFIDANDIQRVCFYHLV
                     PTGRGVEVQTLTQEEARNAMDTLIARVEEWKAEGKNREVLTVTQPADGIYLLLRQLREG
                     SPLAKETLGLLQWNGGGANSSGRGIANIDTQGAVHPDQFWQSVTLGNVKSDRFSDLWDA
                     RAGAAAEMLPELRGSDDPLERQKKIEGRCGRCVHFALCGGGFRTRAAFANGHWYGSDPG
                     CYLTEEEISTPLPEIK"
     CDS             22192..23493
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_914"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 1.8e-134,
                     bitscore: 445.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRMMNQELRPETLCVQAGWAPKKGEPRVLPIYQSTTFKYETSEQ
                     MAKLFDLEEAGFFYTRLQNPTNEAVARKIAELEGGVAAILTSSGQAASFFAIFNICEAG
                     DHIVSASAIYGGTYNLFAVTFRKMGIEVTFVDQDAPAEEIAKAFRPNTKAFFAETISNP
                     TLCVLDIRKMADIAHAHGVPLIVDNTFATPINCRPFEWGADIVTHSTTKYMDGHAAAVG
                     GVIVDSGNFDWEAHKDKFPGLTEPDPSYHGLSYSKSFGKGAYITKATVQLMRDLGSIQS
                     PQNAFLLNLGLETLHLRVLRHCENAQKVAEFLQGQEDVAWINYPGLSSNKYYELAQKQF
                     RGGQSCGVVTFGIKGGRERSIKFMDSLKLAAIVTHVADSRTCVLHPASHTHRQLTDEQL
                     MEAGVRPDLIRFSVGTEAAEDIIADLKQALEAIR"
ORIGIN
        1 gtctccaagg ccagcgcccg ccagcgcgcc ggccgttgcg gccgtgtgtg cgaaggtgtg
       61 tgcatccgcc tgtacagtga gaaggactgg gaggacaggc cggattttac ggacccggaa
      121 atcaggcgca gcgcactggc cggggcgctg ctccggatga aagacctggg attgccggaa
      181 atgccggagt tcccacttcc ggatcctcct tcatccaaac tggtgacgga aggttaccgc
      241 accttacggg agatcggcgc tctggacaaa gcccggcagc tcacgcccgt aggcaaaaag
      301 ctggcgcggt tgcccattga cccgcggctg gcccgcatgc tgctggaggc gcaacatgaa
      361 caggccctgc cggaaatgct ggtgattgta gccggcctgg gcatcatgga tccccgtgaa
      421 cgccctgcgg atgccgctca gaaggcggac caggcccacg cgcagtggaa ggaagaagac
      481 agtgacttcc tatctctgct caaattatgg aaggctgcat ggcaattccg ggagggaagg
      541 cgctggcgta aaaaccagct tcggaaatgg tgcgggagaa atttcctcaa tttcaaccgc
      601 atgatggaat ggttcaattt atgggaggac ctttcccggc tggtcaggga aacactgaaa
      661 tgcagaattt cccctttgga agaagaaacg gagcggcagg cttcctttgc catgattcac
      721 cggagcatct tggcgggcgt tccgcgccag ttcggcctct gggatgcaga taaccgggaa
      781 tatcgcggcg ccggaggacg ttccttcggc atttttcccg gttccggcct gttccgccgt
      841 aaaaaaagga gtgaatgggt aatgggcgtg gagttggtgg acaccacgcg cctgtggatg
      901 cgccgcgcct ccattttgga accggaatgg gtggagcggg tagcgcccca tttgtgcgaa
      961 tcacactatt ccggagcgcg gtgggacagg gagcaagggg ctgtttacgc agtggaacgc
     1021 gtcgtgtgcg gcggcttgcg cattattgat aacaggcgtg tgcactatgg ccgtatcaat
     1081 cccgcccatg cgcgagaaat aatgatacgc gaaggcctgt tgggcggtgg tttccgcacg
     1141 aaacccgcct gtatcaggta tctggaaacg ctccgggaag aggttcggca gatagagctg
     1201 aagttgcgcc gtccggacca ggtctggtgt gaggaaggag tttttgaatt ctttaacagg
     1261 cttgttcccc cggactgctg tacggccagg gcttttttgc ggtgggccgc cggtgtggaa
     1321 aagaaaaacc cggaagctct gcatgttccg ccacaggaag ccatgtacga attctggggg
     1381 aaagacctgc tggatggttt tccggatgaa atcacctgta aaggagcgga atatgccgtg
     1441 tattaccaga atgatcccgg cgcggaagat gacggcgtga ccctgggcgt ccacatcgac
     1501 cagttgccgg atattcccga atggttgccg gagtgggggg ttcccggtca tctggcccag
     1561 cgggcggaat gcctgctgcg ttcccttccc aaggatttgc gcgtctttct ccagcctatc
     1621 agccaaaagg ccgcttactt tgcggaactg aggcatggcc tggaaccgga cgggccgctg
     1681 gcggggaaac tggcggaatt tgtggaagtg gaaacgggaa aattttgcgc gccctccttt
     1741 tttgacatga accgtcttcc tgcggagctg gttacgaaga tatgggtgtg cgatgatgaa
     1801 ggggaagagc ttgccatggg cacggatgtt gcggaactga ataaccgcct gggtaaaaaa
     1861 ctttcccgcc ggttccagga aacagcggag gatatcgtgt ccgtaaccgg catgaaggaa
     1921 tggagctgcg gagatttgga atacacggtg gatgtggcgg gaaggccggg ttatgtggct
     1981 ctggtggatg aaggagcatc cgtgggcgtc cgtgtctttg aggatgaact gagcgctgcg
     2041 gaatcccacc gggaaggatg cctgcgtttc atgcgcctgc gccagacgga ccagcttaac
     2101 catctccgca gaaaatttcc gttgaagctg gaaggaaagc tctctcttca tatgctcgga
     2161 cgggagccgt ctaccaatgc ggaagacctg gtggacgttg ccgcggagat agccatgggc
     2221 cgtcctttgc cgcgcacggc ggagcaattc gctgctgcgg aaatgaatct gcgccaaaac
     2281 ctttttgacg cggcgcataa cgtggcggat atatgggaac tggtggcggg tacggaacat
     2341 gccgtcaggg actttacggc gctgcaaaag ggcgtgcgcc atacggagcg catcacggct
     2401 gaccttcagc gccagcttga ctggttgtta cgcccccgtt tcctgtgggc gcatggagcg
     2461 gaacgcttgc cggacctgaa acggtacatg cagggaattg cggagcgtat cagacgcatc
     2521 ggccagcaac cccttgccag ggaattggaa cgcctggacc tctttgaacg cgtgtatttt
     2581 ccctggcatc aggttttgaa ggaacatgcc ggagacctgc gctggatgca atacggttat
     2641 ttgctggaag aataccgcct ggccgttttc gctcccgcca tctccgtcaa gggccgcgtc
     2701 tccgaaaaac gtctggtggc ttcttttgag gcattgtcaa gccagtaaaa ccaggacgga
     2761 ggctgtttgc acaggcggct tatccggcgc ctttttctga aatggagagg gataccctca
     2821 gcctgctcgc ggaagatggt ttacaatcct ttggataatt gggcgaattc aatcaaattg
     2881 gtttccttgc cgaacaggac cagaatgtcg tggtcttcaa aaacgagatc cggggaaggg
     2941 gtgccaatga cgggaatgcg cggtatggac aggatttccc ggcgcccctg cggagtctgg
     3001 gcctccccgc ggcggatggt gagcaggttg aggtggtgtt ccgtgcgcag gcctacatcc
     3061 cgcaggcgct tgcccaccca gatgcgcggc acggctattt ccacgatgct gtggttttcg
     3121 tccatggggg aaacgcgcag gaattccggg gattccaact ggctggcgag ctgcttggaa
     3181 gccacgcggg acaagttgat gagcgcatac acgttcatct ggcttaaaat gtgttcgtgc
     3241 accggactca tgacgcgggc gtagatgtag cggacgccca ttttctgaag gtgcgtgacg
     3301 acgagaaggt tttcttcaaa actgtctccg atggcgacaa tgacggcgga ctggtcgtcc
     3361 agttccaact cacgcaaagc ggccggatta gtgtaatccg tcaccacggc ataagtcacc
     3421 agatccttga tttgctccaa ttcttcatcc gtggaggcaa cggctactac ttcaatatta
     3481 cgggcggaaa gttctgtgca gagttcctgc ccaaactggc ccaggccgat aacggtgtat
     3541 ctcataatgg tatattcagg ttaacgggat tttgacggat ggatagcggt aatgcctcgg
     3601 agtaggggtg ccggccagcg caatgagaaa agcgaagagc cccacgcggc cggcgagcat
     3661 gttgacgata agaaggtatt tggaagggcc gcttaaatct ggagtaatgc cccgcgacac
     3721 gcctaccgta gcaaaagcgc tacagttttc aaagaagata tccagagaac tcatggaggg
     3781 ctccagggcg caaatcagga cggtaaagca gccgatccag gcgcaggaga ccaccacggt
     3841 aatcacgcag cgcgccacgg tgcgctggtc gatgcggcgg cggaagaatt ccacatgatc
     3901 cctgccgcgg aggatgcgca ggatttccgc gcctgcaatg gcgcaggtag tggttctcat
     3961 gccgcctgcc gtgccgccgg ggctgcctcc caccatcatc agaccgcaca taatgaggct
     4021 ggctgcgggc agatagcggc cgtagtcgct gatattgaat cccgccgtgc gtgccgtgac
     4081 gctgtcgaaa aggcaaatcc agaggtgttc ccccaacggt tccgcggcat ggggagagga
     4141 aacggcaaag atggccaggg cgcctcccgc cagcaaaatc cccgtggaga tcatcaccag
     4201 tttgaagtaa ggggtccact gcatgtgcag gcggcggtgt ttggaaaaaa agcggtttgc
     4261 caggcgtgaa ttaatttcct tgtaaatgcc gaatcccagg ccgccgcata cgatcagcgc
     4321 catgatgacc gcctgcccgc tgtagcacag gcggatgccc ggctccatca aattcatcgg
     4381 gaaagttgaa aaaccagcat tgcaaaaggc ggaaacggag tggaacaggg aatgccacca
     4441 caaaggctcc cccatcaggt tgatgtcctt cccttcccag gaaaaataaa gaaggacggc
     4501 gccgcacagt tcgatgaaca gcgtactgac cacaatagtg gtaataaagg agacgacggc
     4561 tcccagattg tcttcatcaa gcagatccgt cagcagcacg cggtccctca gggaaaaacc
     4621 ctggcctgcc accatggcta cgaagtaggc gaacgtcatg atgccgaatc cgccaatctg
     4681 gataagggca agcgtgaaca tttctcccag cggggtaaaa gtatgggcaa aatccacggc
     4741 gttcagaccg gtgacgcata ctgcgctggt gctggtgaac agggcatccg taaaactgag
     4801 tgtaataccc ggatatgtgg aattaggcag cagaagcaat ccggtgcctg ccaggatgac
     4861 tactcccaga gaagctacaa actgcatggc gggggccata agaggccggc cttttttttg
     4921 cttgcccacc agccattcaa aaatcctggt cagggacatc agcgtgggga tggcaatcag
     4981 cccggccgta atcaccaggc gggaaagctc cgtgaacctc atgtatcccg cttcctgttg
     5041 ttccctggca atcaggagaa aaatcatgag gcagctgatg atttggaaaa tcaggagcct
     5101 cagggaaggg cggttgattt ccttccggaa ataggaaccc agaatacccg tcaggtggcc
     5161 cagcgtggca acggctgcaa tcagccgcga ccactcatgt tccgcccgcg tcaggggcca
     5221 gcccagctcc cagaccaccg cccccagaag aatggcaatg cagacggctg caagtttggt
     5281 gaatcccgag cgtgtagtgg tcatgaatgg aaatgcctta tgcggactct accacctgga
     5341 catggaaaga aaagctctta ggccgtttta tgcatgcggg cgggaaaggg gcagatgccg
     5401 cactgcgttt cttcatggcg gggcagggcc ggccggaaag tgagtggaat agtgatattg
     5461 atgaatttca gtaaatttct cttactgtgg atatgcggga tggaaacgct gccgaagagg
     5521 gccttggtca aaaagggaac atgtttatca aaaggcatcc cgcggcaagc cgtattttag
     5581 gcttttcctt tggcggcggt gatggcttga tagggccgtg ctggctaaaa gaatcattcc
     5641 gtgtctggac gtaacggacg gcagggtcgt caaggggacc aatttcatta atctgagaga
     5701 tgccggggat cctgtagaat gtgccagggc gtatgatgcc cagcaggcgg atgaacttgt
     5761 ttttctggat attaccgctt cttccgatgg ccgtgccacc atggcggacg tggtgcgccg
     5821 cacggcggca tgctgcttca tgccgctgac ggtaggcggc ggcatccgtt ccgtaaagga
     5881 catgcgcgaa atgcttctgg cgggtgcgga caaggtttcc ctgaatacgg cggccatcaa
     5941 taggccggag ctgattaatg aaggtgcggc ggcttttggc agccagtgca tcgtcgtcgc
     6001 tattgacgcc aagcgccagg cttccggcaa gtggggcgtt tccacccatg gaggccggaa
     6061 attcgtgggg ctggatgccg tggaatgggc tgtggaggcg gaacgccgcg gagccgggga
     6121 aatcttgttg accagcatgg atgcggacgg agccaaaacg ggttatgata ttgaattgac
     6181 ccgcgccgta agcagtgcgg tgcgcattcc ggtaatcgcc agcgggggtg cgggtaattt
     6241 ggatcacatg gtggatgtgc tggtggaagg gaaggcggat gccgtgctgg cggcttccat
     6301 tttccatttt ggggaataca cggtgccgga agccaaggct tactttgctt ccagaggaat
     6361 acccgtacgt cctttggcgg aatagcggaa acagcttttc ttttgagaga aaatgaaatt
     6421 ccggtgcgta atatgcgtat gcgctgtctt ttttttcctc tgtgttccgc tattgcctta
     6481 acgtcttttg tccaggccca gtccctggag aggcatcccc tgtatgaacc cgcccttgtt
     6541 tccgcaggaa ctccgggtga tgcaggtaat ttatttgccg gagccaaagt aaccgcttcc
     6601 ggtcattacg gcagtgaccg tccggaactg gccgtggacg ggcagacgaa taacgccggc
     6661 aaatactggg gttgcgaggg cattcccgtc tggctccaaa tagatatggg aaagccccgg
     6721 acgctttcct ccctgcatgt atggccctat tgggaaggag gacgcattta caaatataaa
     6781 atagaaggtt ccgaagacgg aaagaactgg aaaatgttgg tggatcagtc ttccaacagc
     6841 attgccgcca ctccggaagg agttcccttc aaattcaatc cgcagacggt ccgttacgtt
     6901 aaaatcactt ttttgggcaa tagcgccggc aatgagaagg gggggcatct ggtggaaatc
     6961 aaagggtacg gacccgatgc cgccctgagc ctgcaggctg cagcggtgaa ggattatgac
     7021 cgtattcctt acaatggcgc tcccgggcag gaaatgcttc aggatgccgt gcgtctgtcc
     7081 ggctggagag gcgaacgcgc cggcgggcag attgccgtct ggtcttccca ggcgcagccc
     7141 cagttatcgg cctcctgcgc cggggtaaaa aacgctgccg gacagattat ccctgtccgg
     7201 actgccatga tacgctacac cagggggggc aacaggctga tttcagatat catcggcagc
     7261 gaaaacagct gcgatttgca agccggaggc gtgcgtccgg tatgggtgga ggtcaatatc
     7321 cccccgtctg ccaaacccgg cgtgtacaaa ggaaaagtgg tagtttccgc agaaagcggc
     7381 tctcccgtca gtgtgccggt aattctggag gtggcgccgg aatccctccc tgctcccgca
     7441 cattggcaag ctcatctgga cttgtggcag catccgcagg ccgtggcccg ctggcatgat
     7501 gtggaaccgt ggtctccgga gcatttcgca ctgatgaagc cggtgatgaa aaggctggcg
     7561 gatgccgggc aaaaggccat tacatgctcc ctgattgatg aagcctggaa tgcccagact
     7621 tatgactggt tcccgcccat gattgaatgg gtcaagggca aaaacggaac catgcgctgg
     7681 aattacgcca attttgacaa gtgggtttcc ttcatgatga acgaggtggg cgtcaagggg
     7741 cagatatcct gctataccat gattccctgg aacatgaaaa tccgttattt ggatgaggcg
     7801 accggaaagt acaaatttct ggatcttaag ccgaacgatc cctcctatga agctatctgg
     7861 gggcctttcc tgacggattt tcgcaagcac gtcaagagca agggctggct gggcaaaacc
     7921 tgcatcgggc tggatgaacg gccggacgct atggtcaggg cggccaagaa tgtgctggac
     7981 aagtatgccc cggaattcaa aatcgtttcc gccgtcaatc ggcctacggc catgacccgg
     8041 gacgtttatg acgtctctcc tgtaattgac catgcaggca cggtcacggg cgatctgctg
     8101 gcgcagcgta aaaaggaggg aaaaaagacg acgttctatg tctgtgtcca tcccaaaaag
     8161 cccaacacct tcactatttc cccgctggcg gaggcggaat ggcttcccct ctttgccgcc
     8221 gccaatcatt tggacggctt tttgagatgg gcttataatt cttggaaccg taatccgttt
     8281 gaaaagaccg atttcgggaa ctggcccgcg ggagactgct accttgttta tcccggcaat
     8341 ctcagttccc tgcggtttga aaaactccgg gacggactgg aggaatttga aaaggtcaat
     8401 atcctgcgcg cccgcgccgc aaaaaatcct aaggcgaaag ctgccgtagc ccgcatggat
     8461 gaagagcttt ccaagctctt taccgtggaa aaaagccgcg gggattccca tgaggaagac
     8521 gtgcggaaag cccgcgaaat tatccgtaaa acgacggaaa tttcccgctg acctttcttg
     8581 cgggaaaaag ggaaactgct gtatttccat gtctttccgg aggttcggtt aagctccgga
     8641 aaggggggag gatcagcggt tttctctttg gtatttcgat ccccattccg ccatggaggc
     8701 caggatgggg cgcagactgc gccccagttc cgtaagagta tattccacgc gcggaggtac
     8761 ttccgcatac acctttcgcg taagcaggcc gtccttttcc atagaacgca ggttcgcagt
     8821 cagaactttc tgcgtcacag gcccaatgga tttgcggagt tctccaaacc gccgggtgcc
     8881 ttcgagcaga tcgcggagga tgagcacttt ccagcgggag gaaatcagtt ggagagtagt
     8941 ttcaacaggg catgatgaat tatagtaagt catttatttt aagcaatagt ttctttcagg
     9001 aatccagggt actattttct gcctacttta caaaaagaat gttgccgcct attttaataa
     9061 gtgcctgccg ttacggcaag catgaacaga taatgccatg aacaagatca tcattgccaa
     9121 ttacagggag acggagcctc aggttatcag ccgggagggt aattcctttg cggtaaagcc
     9181 cgtcatccgg gaagcggatg ccggaaaatg tgcggccagt ttcgtggaag tggagccggg
     9241 gcggtacgcc tatggctacc attatcatga agtgaatgaa gaggtatttt acatcatcag
     9301 gggccatgcc gttgtgcgta cgcctgaggg tgaaaagaat ttaaaagagg gggatgcgat
     9361 tgcattccct gccagcccgg agggagcgca tgttatccgc aacggatccg ctacggagaa
     9421 gctggtctat ctggatgtgg gcactcgcct gacgcctgat gtggtgcact tcccggatac
     9481 ggcatccgga atggtatatt cctcctccgg tgtgcaccat tttcgggaat cttgaagcag
     9541 catccctgtt ttaaagcctt tttccggttt ttccaccggc gcggtccgca ggaaagcggg
     9601 ccgcgctcct ctggggagga aggtgtgagg aaacagtatt cccctggccg catgaaatgc
     9661 ccctctttgc cttggacatg gctggccgca aaggctgcgg ttcattgaag gccttcaaaa
     9721 cctccatgcg gaaattaacc cgtataaggt gatatattaa aacccggcct tgcagcaagg
     9781 tgtgcgccct tttttgtgct gcgggggaag gatgaattct ccggctttca ggaagggaaa
     9841 gtactggcgc gggaagcctg cttgcgtggc tgtatggcgg ggcggaaaag cagtcccctc
     9901 cccgaaatat tcatggtttg tttttcatga atatccggca gtaaaaaacg cccctgccgg
     9961 ataagccgga caggggcgtt gaaattaagc ggcctatacc ttattccgca ggtttgtcgg
    10021 cacccatgcc ggcaatgctt tggtacaggt tccagcggtg ccagacatcc ttctgggctt
    10081 cttcaaggag tttttcgaat ccttccttat tggtcttcgc cagaagtttg aagcggtttt
    10141 cgctgagcag cacatcgcgc agatcgccct tcgggccctt gccttccaca atcagtggat
    10201 tcttgccctg gcgggccagg tccggattat agcggtaaag caggactcgg ccggaatcca
    10261 cccatgcctt ctgctgctgc aggcccttgg ccatattgat gccgtgggag atgcagtggg
    10321 agtaggcgat gatgagagcc gggccgtcat aggcttccgc ttccacaaag gctttcagcg
    10381 tgtgttcatc cttggcgccg agagcgacgg aggccacgta cacgttgccg taagtcatgg
    10441 ccatgaggcc cagatccttc ttcacgccgg gtttgccgtt cgtggcgaat ttggctactg
    10501 cggcgcgcgg ggtggatttg gagcactggc cgccggtgtt ggagtatact tccgtatcca
    10561 tgaccagcac cttcacgttc cggccgctgg ccagaatgtg atccaggccg ccgtagccga
    10621 tgtcgtaggc ccagccgtcg ccgcccagaa tccacacgct cttgcggaca agtttatccg
    10681 caagggtcag gaggcgcgcg tattccggct tgccggcaat tttcttcttg agttcttcaa
    10741 tgttttcacg ctgctgggcg atgtctgctt catccttctg cggattagcc agtatccggt
    10801 ccaccagttc ctggcccacg gcgccggcag cttcatgaag aagctcaatg gcgtgttcca
    10861 tctgcttgtc cagggagacg cggaagccaa ggccgaattc ggcgttgtct tcaaacaggg
    10921 agttggccca ggcggggccg cgcccttcag agtcatggga ccacggggtg gtgggcaggt
    10981 tgccgccgta aatggaggag cagcccgtag cattggcgac caccaggcgg ttgccgaaga
    11041 gctgggagag catttttaca tacggagttt caccgcagcc ggcacaggcg ccggagaatt
    11101 cgaacagcgg gcgcagcacc tgcatggagc ggatgttgtc cgttcttacc ttggtgcggt
    11161 ccacgtccgg aaggctcagg aagaaattcc aattggcttc ttccttgtca tgaatcttcc
    11221 cggccgggac catggtcagg gccttgtgtg tcgggtccgt cttgctcttg gccgggcaga
    11281 cgtccgcgca gagcgtacag cccgtacagt cgttcgggga aatctggatg acgaatttct
    11341 ctcccttcca gtccggatgc ttggcatcca ggcattcaaa cccttccgga gcgtttgcaa
    11401 gagcgtcagg agagaagaat ttgctgcgga taaccgcatg cgggcagacg gcggtacact
    11461 tgccgcactg gatgcagagg gtcggatccc attccggcag atccagggcc agattgcgct
    11521 tttcgtactg ggacgttccg ttcgggaatg tgccgtccac gggcatttgg ctgaccggga
    11581 tgctgtcgcc ttcaccgcac atcatcttgc caaggacgtt ttgtacgtag tccggagcgt
    11641 ccggggacat ggcgggcgga atggcgtgtc cgtttacagt ttttccggtt gtgtccacct
    11701 ggtgcaggtt ttccagcgtg gcgtccacgg cggcgatgtt tttgtccacc acttcctggc
    11761 ccttcttggc gtaggttttg gcaatggcct tcttgatgta gccgatggct tcatccgcgg
    11821 gaatcacgct ggccagcttg aagaagcagg tctgcataat catattgatg cggccgccca
    11881 tgcccgtttt gcgggccacg gcaaaagcgt caatcgtgta gagcttgatg ttcttgtcca
    11941 gaatctgctg ctgcatgcgg gcgggcagcg tgtcccagag tttgtccgcc gggtgcgggc
    12001 tgttcatcag gaaagtggcg ccgttggcgg cattcttcag gaagtcgaac agatccagca
    12061 gggaaggctg gtgcagggcc aggaagtttg ccttggtgat caggtatgtg gatttgatcg
    12121 gacggggacc gaagcgcagg tgggaaatgg tggaggaacc cgatttcttg gagtcataca
    12181 cgaagtagcc ctgcacatac aggttcgtat gctggccgat gatcttgatg gcgtccttat
    12241 tggcgcctac ggtgccgtcg gaaccgaggc cgaagaacat ggcccgcgtc acgtcgtccg
    12301 cttccgtgga ataatcttca tcatacggga ggctggtgcc cagtacgtcg tcgttgatgc
    12361 cgatggtgaa atgattcttg ggagtgtcca gagccaggtt gtcatagacg cccttgacca
    12421 tggcgggggt gaattccttg gaggagaggc cgtagcgtcc gcctaccacc ttgggcatgc
    12481 cgttggtgaa gggcagcgtg ccgttggcct gggcgtcgaa gagggcctgg atgatgtcct
    12541 ggtggagcgg ttctccctgg gagccgggtt ccttggtgcg gtccagcacg gcgatcttcc
    12601 tgaccgtagc ggggagggcc ttgacgagtt cggcggcggg gaatgggcgg aacaggcgca
    12661 ccttcagcac gccaaccttg gcgttttccc gggtcatcat ggcttctacc gtttcttcca
    12721 cagcttcagc gccggatccc atcaggataa tgacgcgttc ggcgtctgga gcgccggtgt
    12781 aatccaccag atggtaggaa cggccggtaa gttccgcgaa tttgtccatg gcgttctgga
    12841 caatagccgg agtggcttca tagaaacggt tgaccgtttc acgtccctgg aaataaacgt
    12901 ccgggttttg ggcagtgccg cgcagaacgg gagcatcagg ggtcagggct cgttcccgga
    12961 aggaatccag ccattcctgc ttaatcatgc cgttcagggt atcgtccgtg atgtctgcaa
    13021 tcttgccgat ttcatgggac gtgcggaacc cgtcaaagaa attaatgaaa ggaatgcggg
    13081 attccagtgt agcggcatgg gaaatagcgg cgaagtccgc agcttcctga gtggaggagc
    13141 cgcacagcat ggcccatccg caggagcggg cgctcatcac gtcgctgtgg tcgccaaaaa
    13201 tggaaagggc ctggtaagcc agggaccggg cggctacgtg gaacacggcg ggagtcagtt
    13261 cccctgcgat tttgaacatg ttcgggatca tcagcaggag cccctgggat gcagtgaacg
    13321 tagttgcaag cgctccggtc tggagggcgc cgtgaacggt gcctgccgcg ccgccttcac
    13381 tctgcatttc caccacggag ggaacggtgc cccacaggtt cttcctgttg acagcggccc
    13441 agctttcagc tgattcaccc atcggagaag atggtgtaat ggggtaaatg gcaatgactt
    13501 cagaaaaacg ataggctacg gaggctacgg cttcgttagc gtcaatcgtg ctgtaagtta
    13561 cggttgtctg atcactcata agtctgcacg gatagtatat aattgataaa taaggtgcgt
    13621 cttaacggga acatttataa catgtctggt gccaaaggta aaagcaatta tgcgtatgtg
    13681 gggctttgcc ggccattttt taataataag accagttttg tttcaattcc tttggatatc
    13741 gtgctttatg tggttctgtc caagcttttt gcaaaacggc cggagtactg gggaatgttc
    13801 cggcatccgg cttccgaaaa agggggggaa ggaaccttcg ggtcaaaacc ggccgccaaa
    13861 aatgtcccct ctgcctgaca atgcgctagc caaaacggaa gcaagccttt agaatccccg
    13921 cactatgtcc gaacaacagc aggcacatcc gaccacgacg gaatccgaac ttattgccgt
    13981 gcgccgcgac aagctcgcca aaatccgtga gctgggaatt gacccttacg gcgcaagatt
    14041 tgacgtgacc accactcccg ccggattgaa agccgatttc caggaagaca aacaggtagc
    14101 cgtcgccggc cgccttctgg ctattcgcga catgggcaaa tcccagtttt tcgtcattgg
    14161 ggacgtacgg ggaaaaatcc aggggttcct gcataaaaat gaggtggatg aaaccacctg
    14221 gaagctttgg aagctcctgg accgcgggga ctgggtcggt atcaggggaa ccacgttcct
    14281 gacccgtacc ggagaaccta ccgtaaaggt atccggactg accattcttt ccaaaagcct
    14341 ccgccccctg ccggacaagt ggcacggact ggcggacaag gaggtgacct accgcaagcg
    14401 ccacctggac ctcatttcca atgaggaaag cgcctccctg ttcgttacgc gctccctcat
    14461 gattgcggaa atccgccgct ttctccagga acgcggttat ctggaagtgg aaacccccat
    14521 gcttcaggat gtggccggtg gggccgccgc caagccgttt gaaacgtacc ataacgcgct
    14581 tgatatgccg ctgacgctgc gcattgcccc ggagcttttc ctcaaacgcc tgatggtggg
    14641 cggcttcacg aaaattttcg aactcaaccg cagcttccgc aatgaaggaa ttgaccgccg
    14701 ccacaacccg gaattcacca tgctggaagc ctattgcgcc tgcggtgatt ttgaaaccat
    14761 ggcgaatatg gtggaggagc tcatctgcca tctggcggaa aaattctgcg gcggccttca
    14821 gattgaccac aaggacgctg aaggcaacgt tctttacaca atcgacctca gccgtccctg
    14881 gaaacgcgcc gactaccagg acctgatccg gggcgtggcg ggggaagact ggtttgacat
    14941 ttcccccgaa gcgcgccgcg cccgctgtga agagctggga gtggaaatca gcccggatat
    15001 gaaagatgtg gatgtttccc agcaggtgta tgaaaaactg gtggaggaaa agaccatgaa
    15061 cccctgcttt gttacccacg tggccaagga cctggttccc ctggccaagc tgaaccggga
    15121 aaatccggac gtagtggatg tatatgaact ggtgatcaac gggcaggaaa tttcccccgg
    15181 ctattcggaa ttgaacgatc ctgacgtgca aaaggaacgc ctggagcacc aggctgccgg
    15241 ggagacccag cgcgtggact atgatttcat tgaaacgctg gaatacggaa tgccctccgc
    15301 aggcggcatc ggcatcggca tcgaccgcgt cgtcatgatg ctgacggggg cttcttccat
    15361 ccgtgacgtg ctgctcttcc cgcagttaaa acgtaaggac agttaatccg aaccaccggc
    15421 cgcatggctc cccgcacccc ggatattctg gactgcgctt ccgcccaatg gatcggcaaa
    15481 cgccgcgagc aggaagacgt ggttaaaagt cttcccgccg ctggcgggat gctaggcatc
    15541 gtgtgcgacg gcatgggagg gcatcttcgc ggagattgcg cctcctgtgt ggtggcgcag
    15601 gaatttgccg tggtatttgc ggaaagcggc atcgaggata tcccggaacg tttaacggcg
    15661 gctttgcatg ctgccaacag ggcgttggcc gccattcaga aggaaccgga ggaatccgga
    15721 accacattgc tggccgtctt catccgcgac catttcctgt ggtggatcag cgtgggagac
    15781 tcccccctgt atttatggag cggagcggac agctttcgca tggaccgtct gaatgaagac
    15841 cattccatga gaccgattgc ggattgcctt taccggaagg ggaaaatgtc acttcagggt
    15901 gcgcttcggc agcgttgcat tctccgttcc gccgttatgg gcggtcccat ggaactggtg
    15961 gacatcagcg ccatgcccct gctcctgcat ccgggagatg cggtgctggc atgctcggac
    16021 ggcttgcagg tttggagcga gctgttgaga gaaccttctt tcctggctct tcaaaaggcc
    16081 agggattgtt ccagcaggga gctggtgggg atcattatgg aacaggtgaa ggatatgctg
    16141 gagccccagc aggataatgc ctccgtctgg gctgccgtca tgcggaaacc ctgcgagggc
    16201 ggtaaataag cttattccgg cgaaggaagt gcgggagcat ggttctgggc gggcgggaaa
    16261 atgttcgcgc tgttcttatt gcgccttaaa cagggctttt ccgcagaccg gggcacggag
    16321 agccttgaaa atgaggatct ggaggaggct gtcaggtatg gtgttctttt acaggagcaa
    16381 cccctccgga aagaaccggg ccggaggtga tttccccatt gtcatttgac cggcggggga
    16441 ttaaaatgca ctccgcacaa catgattgcc tggatagttt tctattacct gatcggagcg
    16501 attccgttcg gctaccttgc cggcagaatc agagggattg acctgaggca gcagggttcc
    16561 cgcaacatag gcgctaccaa tgcgtggcgc gtactgggct ggaagtgggg cctttccgtt
    16621 ttcattctgg acttcttaaa ggggttcatc cctgtgttcg gcgccttgaa ctggctgccg
    16681 ttcctgacgg gggatgcggg cggctgggat ttcaatgtct tggtagttct ctcctgtttc
    16741 gctgttatac tcggtcatac ttacacttgt ttcctgggat tcaggggagg aaaaggcgta
    16801 gcgacaaccg cgggggtttt atttgccctc aatccggtgg tggcttgcgt agctctggct
    16861 tcttggctgg tggttatggg aatctccggc atcgtgtccc tggccagcct ggtggccgct
    16921 gtggtgatga tcgccgccgg atggtggatt tatccgcttt gccaggacgg ggatgtctcc
    16981 ccccagatac tttacgtcgc ctttttcacg gtggtaggcg cgctggtgat tctcaagcac
    17041 cgttccaata tcgcaaggct tctcaacgga acggagcact ccttctattc caaaaagtcc
    17101 aagtaagatg atgaatcggt tacataaaat agcagtcatt ggagccggtt cctggggcac
    17161 ggccctctcc atggttctgg cgacccggga atgtgaagtc gtcctgtgga cgccggaaga
    17221 ggctcaggcc aggcagcttg ccgaaacaag acgcagcccc gtcctttcga aaaccgccct
    17281 tcccctggcc tccaatatcc atcctacttg cgacctgggc caggtgaagg atgcggaact
    17341 cattgtagta gtggtgcctt ccgtagccat gcgttccgtg gcccagcggc tgcgcagcct
    17401 gccggtgcag ccggatgccg tcatcgtctc ctgcaccaag ggcattgaac agggaaccca
    17461 taaaagaatg acggaaatcc ttcaggaata tctgccctcc aaccccatag gcgtgctttc
    17521 cggtcccaat catgcggaag atatctgcct gggccttccg tccgcctccc tgattggatt
    17581 tgaagatccg aagtatgcgg attgggtgca gcagatattt gcatccaaaa ccttccgtgt
    17641 ttattccgct acggacatta tcggcatgca gctgggcgga accattaaga acgtctttgc
    17701 catcggggcc ggcttatgcg aagggctgaa cctgggggat aacgcccagg ccgctttgct
    17761 gacccgcggc ctggcggaaa tgacgcgcat cggcgtggcc agcggaggcc gcagggaaac
    17821 cttcatgggc ctttccggag taggcgattt gattgttacc tgctattccc gccactcccg
    17881 caaccagacg gtggggcgga gactggcgga agggaagagt ctccaggaaa tcctggatac
    17941 cctgggcatg gtggcggaag gggtgcccaa cacgctatcc gtctatgaaa ttgcgcggaa
    18001 gctggaggtg aggacgcccc tgattgacgc cgtttattcc gttctttatg aatccaagcc
    18061 gccgatggaa gcgcttgcgg aactcatgac gcgggacccc cggccggaat tagattgatt
    18121 ttttgttttt ttgagttgct ttccctcgac aaattatact atataaacaa tcagtatgaa
    18181 acgtgccatc atctcagctc tttttgccgc cggcgtcgtt ggtgtcgcca gtgcggacat
    18241 tcaggctccc cctgcttccg aatacacccc cacccgcaag ctgggccgcg ccatcgccaa
    18301 ccttatttat tccgttgaag aaattccgct gggaatcatc aactggacga gccgcgaggg
    18361 agattatgcc ggtttttccg taggcattgt tgatggcacc gctaccatgt ttgaacgcat
    18421 gggctacgga atttatgaac ttgtcacctt ctgggctcct acttacaaat gcacgtacaa
    18481 gcccccttat caggggcgtt gcggcatgag cggcctcaag gaatacaatc ccaatggcgg
    18541 cctgagcgaa ttccctgcgg aactcagctt ccagagctac tacaagtatt cacgccagca
    18601 gcgcgactaa ggccgggctg ttaagatttc aaaagggctg tccgcaaaca agcggacagc
    18661 ccttttttca tatagtggtc ttgacaatag ccgccattga cggggaaagg aggaaaacgt
    18721 attcttccat accggaaagg cttccgtatc atgaataaaa ttgttgcttc catcagcctg
    18781 ggcactgccg tttgcataac agcctccgca tttgcccagg attcccatct ttccctgacc
    18841 aggcagagcg ttgccagcat gcatgaaatc gcagcggctc tggacaaggt aacggatgaa
    18901 cctggggcgg ccgctgctgt ggaaacggtt aaaaaggttc ataaaaagct gctggacatt
    18961 gggaaaagac agctggagct tcctggtgcc acgcttcagg agcaggctca ggtttccgcc
    19021 cagataacgg aagcacagaa aatttcaggt gaattgataa aatctctgtc ccgtttgaag
    19081 aaggaaggtc tgcttacgcc cgatttgcaa aaagccctgg cggatttaca gtctgttcag
    19141 aaggagctgg cgcaggcttc ccgggataag gctgagcagg cggagccgtt cccggaggat
    19201 gcggagggca acacgcatga aaccctgcta accaaaactg tggaggaagt aaaaaagctt
    19261 aacgactctc tggccagggt aagggatgaa gaaaccggca aggctgctgt ggaacagata
    19321 ggtcgctacc gggcggctat gctggacgtt gccaggaaac aggctgccct gccgcctctc
    19381 acccgcaatc agcaggccaa gctgatggga gtgcagcagc agcttgtgga aatgatgcag
    19441 cccattgtca agcatgtaac ggccatcatg ctttctccgg atgcttccag gaacctgaag
    19501 gaagctctga attccctttc cgaactgcct aaggaagttc aaaaaatccg tgaagaggcg
    19561 gctaagtgaa ctttttaaag gatgcgtcct tttgggctgg tcaaaaaatt ataattgttc
    19621 taaattggct gtcctgaaaa atgcgcccgg tttttagtga aacagatctc aatgaacgcc
    19681 ctttcctggt cttctgggaa gtgacgcgcg cttgcgcgct tgcatgcaga cattgccgcg
    19741 ccgtcgccca gccgcgtccc cacccggatg aattgactca tgaggaggca ttgcgcctga
    19801 ttgaccagtt ggcggaactg cggcctccca tgctggtgct gacaggcgga gacccggtca
    19861 tgaggccgga tattctggaa ttggtccgtg cggcttccgg caaggggctg catgtagcat
    19921 tgagccctgc tgctaccgcc cggctgttgc acacggattt ccatgcgttg aaagaagctg
    19981 gggttcagag catgtcattg agcctggacg gtgcgcatga gagtacccat gacgccttcc
    20041 gcggtgtccc ccacacatat gaacggactc tccgggctgc ggaaatggcg aaggaagccg
    20101 gcatgcactt gcaaatcaac accaccatta ccaggagcac gctgggagaa tttgacgact
    20161 ttgtggagct gatgaaaaaa atgaaaccgg gcatgtggag cgtgtttctt ctggtgccca
    20221 caggccgcgc cgccatggat gagatgcctg cggcggaaga agtggaagcc gtctggaaaa
    20281 aactgagcag gataagccat gaggtttctt tcggcgtcaa aacgacggaa gggcaccatt
    20341 atcgccgcgt ggcgcttcag gaagcccgtg ctcagggaag caagcctgct cgccgcgcca
    20401 ttcccacccg ggacggcaag ggcattatgt ttatttctca taccggggaa atacagccct
    20461 ccggttttct ccccataacg gcaggaaacg tccggacgga tgaccctgga gaaatctacc
    20521 gcacgcaccc ccttttcctc aaactccggg atgacaatgc gttgcagggc aaatgcggac
    20581 ggtgtgagta ccgtaccatc tgcggagggt cccggtctcg cgcttatgcc gtttacggag
    20641 acatgatggc ggaagacaac ctttgccctt atcagcccag gctttcacaa caccatgatt
    20701 aatattacca gactttggac aggggcggaa cagcccgcgg accatttgag atacggacag
    20761 ggccacgggc acggtcgttt tgcagggggc gccgtggaat cctgtgcacc ggcttcgtcc
    20821 cgtgcgcgca agcccattgt ggtgtggaat attacgcgta cctgcaatct caaatgcgtg
    20881 cattgttatg cagacgcctc tgcccggaaa tttaagggag agctggattg ggaccagtgt
    20941 tgcgcggtca ttgatgatct ggcggactac aaggtgaatg ccctcctttt ttccggaggg
    21001 gagccgctgg tgcatccgcg ctttatggaa ctgctggaac gtgccaccgg aaaagggctg
    21061 aaggtgacca tttccacaaa cggcacccgt attacgccgg aagctgcagc gcggttcaag
    21121 gaattgggcg tggcgtacgt aggcatttcc ctggacggca ttggcgccgt tcatgacaaa
    21181 ttccgcggtg tggaaggttc ttttgagcag gcggtgcgcg gattcaggct ttgcagtgaa
    21241 gtggggcaaa agacaggcct gcgcctgact ctgacccgca acaatgtgca gtgcatgggc
    21301 cagattttgg attttattga cgccaacgac atccagcgcg tctgttttta ccatctggtc
    21361 cccactggcc gcggcgtgga agtgcagacc ctgactcagg aggaagcaag gaatgccatg
    21421 gatacgctga ttgcccgtgt agaggaatgg aaagcggagg gaaaaaaccg tgaagtgctg
    21481 actgtaaccc agcctgcgga cggaatttac ctgcttctgc gccagctccg ggaaggctcc
    21541 cctctggcga aggaaaccct cggcctgctt caatggaatg gcggcggcgc gaacagttcc
    21601 ggccggggca tcgccaatat tgacacacag ggtgccgtgc atccggacca gttctggcaa
    21661 tccgttactc tgggcaatgt gaaaagtgac cggttttccg atttatggga tgccagggcc
    21721 ggagctgcag cggaaatgtt gcctgagctg cgcggttccg acgatcctct ggaacggcag
    21781 aagaagattg aaggccgttg cggccgctgc gttcacttcg ccctgtgcgg cggaggcttc
    21841 cgcacccgtg ccgcgtttgc caacggacac tggtacgggt ccgatcccgg ctgctatctg
    21901 acggaagagg aaatttccac ccctttgccg gaaatcaagt agtgagatgc ccggctttat
    21961 tcaccgggga acggttggtt ccgggaaaga ggtatcggag gaattgccgt ttcattcgat
    22021 cgtagggtat cccgcgcgca ggtaaaacgc ccctgtcctt gcggttgatt taccgggaac
    22081 agggggtttt acattgggaa aaacccggaa gcgtgcttcg gcgggggcag gggcgaattt
    22141 gtccatacgt ctggttttcc ctgctttaca aggcaggagg catcgcatag catgccccgc
    22201 atgatgaatc aggaattgag accggagacc ctgtgcgtgc aggcgggctg ggcgcctaaa
    22261 aagggcgaac cccgcgtatt gcccatttac cagagcacga cgttcaagta cgagaccagc
    22321 gaacaaatgg caaaattgtt tgatctggaa gaagccggat tcttttatac acgcctccag
    22381 aaccccacca atgaggcggt tgccagaaaa attgccgaac tggagggcgg tgtggccgcc
    22441 attctgacgt cttccggcca ggcggcttcc ttctttgcca ttttcaatat ttgcgaggct
    22501 ggggatcata tcgtcagtgc ttcggcgatt tacgggggca catacaacct ctttgccgtc
    22561 acattccgga aaatgggcat tgaagttact ttcgtggacc aggacgctcc ggcggaggaa
    22621 atcgccaaag cgttccgccc caatacgaaa gctttctttg cggagactat ttccaatccc
    22681 acgctttgcg tgctggatat ccgtaaaatg gcggacattg cccatgcgca cggcgttccc
    22741 ctcattgtgg acaatacctt tgccacaccc attaattgcc gtccttttga atggggtgcg
    22801 gatatcgtca cccactccac caccaagtac atggacggcc atgccgccgc cgtgggcggc
    22861 gtgattgtgg acagcggcaa ctttgactgg gaagcgcaca aggataaatt cccgggtctg
    22921 acggaaccgg acccctccta tcacgggctc tcctacagca aaagcttcgg caagggagcc
    22981 tatattacca aggcgaccgt ccagctcatg cgcgatctgg gttccatcca gtctccgcag
    23041 aatgcctttt tgctcaactt gggtttggaa accctccacc tgcgtgtgct gcggcattgt
    23101 gaaaatgcgc agaaagtggc ggaattcctg caagggcagg aagatgttgc ctggattaat
    23161 tatccgggtc tttcttccaa taagtattat gaattggcgc agaagcaatt ccgcggtggc
    23221 caatcttgtg gtgtggtaac cttcggcatt aagggaggcc gtgagcgttc catcaagttc
    23281 atggacagtc tgaagctggc cgccatcgtg acccatgtgg cggattcccg tacctgcgtt
    23341 ctccatcccg ccagccatac gcaccgccag ttgacggatg agcagctcat ggaggcgggc
    23401 gtacggcctg acctcatccg gttttccgta gggacggaag ctgcggaaga cattattgcg
    23461 gacctcaaac aggctttgga agctattcgt taaaaagtct tcttggaaaa agccgcctca
    23521 gcaaagtgag gcggcttttt ctttatcatt aaggattgga taaaggggac agcggattg
//
