LOCUS       c00101_NZ_AOMC..       13638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AOMC01000132.1 Halococcus morrhuae DSM 1307 contig_132, whole
            genome shotgun sequence.
ACCESSION   NZ_AOMC01000132
VERSION     NZ_AOMC01000132
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:52:14
            Original ID  :: NZ_AOMC01000132.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9694
            Orig. end    :: 23332
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13638
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19694:23172]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13478
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13638
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13638
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(404..769)
                     /locus_tag="ctg101_11"
                     /transl_table=11
                     /translation="MTLPHAVLHLGIDHSSTPIGDVALPTVLAVTAVVSLVVLGLGIVA
                     LAQRRSRSYLLITMALGTLVGRTLVGGLAMDGMLSMELHHLIEHTLDGVMAVLLLAAVY
                     YARTMARPEVNTYERDS"
     CDS             complement(914..2290)
                     /locus_tag="ctg101_12"
                     /transl_table=11
                     /translation="MNERRGLFTFLLGLTTFVGVASAHQVQSSRFTAPIPLSLLFGGAA
                     VTVAATAAWLAITGERSEKGRTWPAFVLPKHVATIVRYGARAVFFAGFLVTIVRGFTGP
                     QIAAENVATVFVWAVWFKGIGLLSILVGSPWRVLSPWRMLYDGLTRIEGDEIAALGSYP
                     SWLGSWPALLGFVVGIGILENLTIVPRSPAATAAVIAGYAAVMVLGAVAFGREWFRRAD
                     ALEVLYRLFGRVAPVGFVTTDDGYRVVFRPPWTGCTYPVERFGLVAFVVATVYTVSFDG
                     FTNTPEFQGLLFGLRNLLSTGPGTSVFIYVLGLTGFVAAFVGVSVVMEAVSESGGWRGT
                     AVAFAPTVVPIAAAYEVAHNYPFVVERLGRLVAVAWSLVVAPIEPLDLLGWLSVPVFWG
                     SQVLLIVAGHVIAVVAAHAVAVARYETLSRARRAHLPLVVLMVGYTVLSLWIISRPVVS
                     "
     CDS             2404..3648
                     /locus_tag="ctg101_13"
                     /transl_table=11
                     /translation="MQTRTVVAVVLLVSVLAGTAFVGYSSLAGSSGTLDERWVSNTSTS
                     ILGNHHAPAAGKIDGEGMVFAPVSGSGNGSSCRLVAMTADGATPQWRYRVPAANCTIHS
                     VADPTLADFDDDGTKEVVATTTEDLVTALDPQTGEQEFTYNLTDYGYTQPLVADVTGDG
                     ANETVVVDFRGTAFVLRPNGSAVWTEKLDAKTEAQPAVADFTGDNESEIAVGAGQKVVL
                     LDRNGTVRWNRTQPFDSSITWMTTGQADEDAAIEIVAATFGGRVVAIDGERGTVEWQKE
                     FGDLAAVHAFGDGDGDSAAEVYATAKDGKLRSLDASDGTVEWTTQLTAEDVPMTPPPGM
                     GDVDGDGEPEIVAVTNDGIVSVVDPKSGDVRASYERNVPIYVHPTIANTDGDRAAELYA
                     VYGDGRVVALSYTES"
     CDS             3773..3982
                     /locus_tag="ctg101_14"
                     /transl_table=11
                     /translation="MTDYTTVSIPKDLADRVEETIEGTSFQSTSDLVRFLLRSIVIQHQ
                     KQGELTEAQFDEIAEQLRDLGYLG"
     CDS             complement(3979..4419)
                     /locus_tag="ctg101_15"
                     /transl_table=11
                     /translation="MSAAHDATGRPAVYATAGLVEALLDLAREAEPEEATIALATTPAG
                     EFAESLPPETPVFTHFYFPDAGQSVSAVFGMDLGTPAGQTQGRFVSHPRGRLALARTDD
                     LHGIVFVAVPPWERGDIAVFSRDGIERSLDLVAAEPPTESLD"
     CDS             complement(4433..5110)
                     /locus_tag="ctg101_16"
                     /transl_table=11
                     /translation="MPMKGSGSAEYEAIDRFDGGVGWLAYPDERMQRASHALATDEGVW
                     LVDPVDAAGIDDLLAEFGDVGGVVVLLDRHKRDAAAFAERHDASVFVPSWMDGVADEID
                     APIERFDGTLGETGYRLRMVATPLWQEGALYHEEDGTLVVSETFGTAEYMRTDSERLGV
                     HPALRLLPPRQSFEDFTPERVLVGHGAGVHEHANPALGAALSGSRRRAPSLYLKTARLF
                     LAN"
     CDS             5184..5870
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyoxalase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_17"
                     /sec_met_domain="Glyoxalase (E-value: 1.3e-08, bitscore:
                     26.0, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISALRWLALEVKDIDHASAFYRERLALDTVRESESEVVLSAGET
                     DLVLRRPSAIPRGGLHTHYALSIPASEYDDWYEQLAGSFDLDEHTFGSARSLYFYDPDG
                     NCVELGESDGEESGVHGMFEVVLEVEELARAESFYTDLGMEIVDQGSERRRTRLAADGF
                     ALELWEPHLGLADARGGVHVDLGVAVGDPKATLDAVVESVRSVERLDDGIRVRDPDGHF
                     VTFVEG"
     CDS             complement(5867..6163)
                     /locus_tag="ctg101_18"
                     /transl_table=11
                     /translation="MSEFDLDLQTVENEIEDETGERTHRVVLGVLDGRTPSEEWIAEIA
                     DDAVLVLAVEGDLNRLASGFASDVREMDGELIHFRKFLLVTPPGVHIDTDRLD"
     CDS             complement(6264..6443)
                     /locus_tag="ctg101_19"
                     /transl_table=11
                     /translation="MAEQSNTWVAFLVGGLAVVLVGAWLLDGLAWFIQYTFVAIGLLLI
                     GYGYYRARLESFLD"
     CDS             6551..6994
                     /locus_tag="ctg101_20"
                     /transl_table=11
                     /translation="MNGASHRKHIPHRRIDRAMGLEKLVQRGSLYGFGAGAVTTGVIVL
                     VASLFDVALGAVVLVLVAIAMLALVLLLGAPGIGPGPAVGEMQSSTGGESGGMQMPSPV
                     EAGGASRNPAAMAAVVPATRLEYVMYFTGFGVAAVVALVVLLG"
     CDS             complement(7090..7926)
                     /locus_tag="ctg101_21"
                     /transl_table=11
                     /translation="MLGMGLTLRPADFKRIVERPRDVAIGALTQWIVMPLAAWGLTIAL
                     SLPPALAIGVVLLGAAPGGTASNVMTYLGKGDVALSVAITTVTTLAAPIVMPTWVVALA
                     GEQLQVTFAEMFTSIVQVVLIPVIAGFVLRLALDRYAPRLAAAGLNVFPAISVVAIVAI
                     VAAVVGANVENILTAGAVVLVAVVAHNAIGLAAGYGVGRASGMSPDRVRACTFEVALQN
                     SGLAVALATAYFSPLAALPPALFSVWHNVTGPALATYFSRQSTETADARAASTGDD"
     CDS             7931..8029
                     /locus_tag="ctg101_22"
                     /transl_table=11
                     /translation="MPSNGVMYGEIQVNVSGVRSAAPENNSTHTTK"
     CDS             8112..8279
                     /locus_tag="ctg101_23"
                     /transl_table=11
                     /translation="MRKHTATVRHSGAKTFGRDPFGVGRSRASSDRPICRPIECDRGPI
                     APPASSLVIV"
     CDS             8605..9645
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_24"
                     /sec_met_domain="HMGL-like (E-value: 5.6e-64, bitscore:
                     207.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTHVIEAGFPVNSDAEFEAVSDIAESTGVTTCGLARVVEKDVEA
                     ALDSGVEMVHVFASTSDVQLEDAMHASRAEMKERSVNAVERAKEAGVEVMFSPMDATRT
                     DEEYLVDVVEATAAAGADWINIPDTCGVATPSRFGELVARVCEVADARVDVHTHDDFGL
                     ASANALAGFENGAAQAQVSVNGIGERAGNAAYEEVVMSAESLYGVESGIDTTRITELSR
                     LVERASEIETPGNKPVVGQNAFSHESGIHAAGVIENSDTFEPGVMTPEMVGAQRELVLG
                     KHTGTHSVRERLHEAGFDPTDDEVRECTRRVKEFGAEKERVTMSVLERFAREVGIEQIG
                     KTEVNA"
     CDS             10001..11803
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_25"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     164.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEGQQTPQTGEPEDAEPETVEATEASERPVTSGAESVARALERT
                     GVETLFGVQGGAIMPVYDALYDSPLDHVTMAHEQGAAHAADAFGIVSGEPGICLATSGP
                     GATNLVTGLADASMDSDPLVALTGQVPSAMVGTDAFQETDTTGVTNPVTKENYFAGDVD
                     SVGDTVGEAFALADAGRQGPTLVDLPKDITTGPTESEPAAGTAPETYDPPERADDEAVE
                     TAASVLAHADKPVILAGGGVIKGEACDELREFATEYGIPVVTTMPAVGAFPEGHDLAME
                     MAGMHGTGYANMAITHCDAMFAVGTRFDDRLTGGVETFAPGAEIIHADIDAAEISKNIA
                     ADYPLLGEASVVIEQVHEAMADERAADMAATGERFQEWVEQCQQWQTDYPMDYPMDEDG
                     PLKPQFVVETVDTATDDDTIVTTGVGQHQMWAVQYWTYTEPRTWVSSHGLGTMGYGLPS
                     AIGARFAADDDQSVVCFDGDGSFLMTLQELAVAVREDLDITVFILNNEAVGMVRQWQDS
                     FHGGRRMASEYPWVPDFAALAEAFGARGFRMEGHDEVADVVEDALAYDGPSVVDAFIDP
                     TEDVYPMVPSGGSNGQFVLAEEQL"
     CDS             11800..12432
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_26"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-23, bitscore:
                     71.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEGLQGPAPEERPQPSGRRNAQGIRIDPEMEAVHDPRRTTLSAL
                     VQNEPGVLAKISGLVSRRQFNIESLTVGTTTNPETSRVTLVIEEPEPGIRQVEKQLEKL
                     VNVISVRELGDDAIRRELVVLKVHGEEPDKVNAITDMYGGETLDAGPRTITVQITGDEQ
                     KIDDAIDAFRQFGIRELARTGQTALARGEEWTTHAEEERYERTQVRQ"
     misc_feature    11923..11925
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             12429..13478
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_27"
                     /sec_met_domain="IlvN (E-value: 3.3e-73, bitscore: 235.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 9.7e-65, bitscore: 208.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHATIYYDDDADSTALEGKTVAVMGYGSQGHAHAQNLADSGVD
                     VVVGLRENSSSRDAVREDGLDVATPVEAAARADVVSMLVPDTVQPAVYDDIADELDAGD
                     TLQFAHGFNIHFGQIEPADDVDVTMVAPKGPGHIVRRDYERGEGTPGLLAVYQDATGEA
                     ADEALAYAQGIGCTRAGVVETSFREETETDLFGEQAVLCGGVTSLIKQAYETLVDAGYS
                     PEMAYFECLNEMKLIVDLMYEGGLGDMWDSVSDTAEFGGLTKGDVVVDEHARENMEEVL
                     DDVQSGAFAREWIAENQANRPAYRQLRQAEKDHEIEEVGERLRDLFAWAEESESNEERN
                     ETERVQADD"
     CDS             13504..13638
                     /locus_tag="ctg101_28"
                     /transl_table=11
                     /translation="MSTVDHTHPDTGRPFGDAVVYQRGPAVAADGGERTNGCLLYTSLM
                     "
     misc_feature    13621..13623
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
ORIGIN
        1 ctcggtcggg cgaacgagcg cgagcgtgac gtggttgcgc tcgtcgcgct ccttcacgac
       61 gacgtcctgc tcgacgagat gatcgagatg ccattcgagc gtgctgcggg cgatgtcgag
      121 ttcgtcggcg agcggctgtg gccgtgtcgg ccctcgatca cagagtaacg caacgatgtc
      181 gccggcggtc tcgcggcgca gcagcgagag cgcgccgcga cgccacgcgt cgcactcggg
      241 cgggtagtag tgggtacggc cgtagcgctg ctcgtcggtc accgcccctg ccgagcagag
      301 tcgcttgagg tggtactgga cctgtccggg cgcgaggtcg agcacgcgca cgagttcgtt
      361 gaaatggatg ccgggcgacg tgtggatgcg ccgcgcgacg cgcttacgag tcccgttcat
      421 acgtgttcac ctccggtcgt gccatcgtgc gtgcgtagta gaccgcggcg agcagcagaa
      481 cggccatgac gccgtcgagc gtgtgctcga tgaggtggtg cagctccatc gagagcatcc
      541 cgtccatcgc cagtccaccg acgagcgtgc gcccgaccag cgtgccgagt gccatcgtga
      601 tcaacagata cgaacgcgag cgccgctgtg ccagcgcgac gatgccgagc ccgagaacga
      661 ccagcgagac gaccgccgtg acggcgagga cggtcggcag cgccacgtcg ccgatcggcg
      721 tggagctgtg atcgatgccg aggtggagaa cggcatgcgg gagcgtcatc gcgcgccatc
      781 atccccgttc gatgcagaac tctccccacg ttttcgacgg cgagggtcga ttccgcggag
      841 acgccgtcga ttcattgcta ctgtttggga acacgtcaga ataatcgttc tggtgcgcgc
      901 gtcgaatcgt cactcacgaa acgaccggtc gcgagatgat ccacagcgag agtaccgtgt
      961 agccgaccat caacaccacg agcgggagat gggctcgcct ggctcgcgag agggtttcgt
     1021 agcgtgcgac cgccactgcg tgggcggcca cgacggcgat gacgtgaccg gcgacgatca
     1081 acagcacctg cgatccccag aagacgggca ccgacagcca accgagcaga tcgagcggtt
     1141 cgatgggtgc gacgacgagc gaccacgcga cggccacgag ccggccgagt cgctcgacga
     1201 cgaacgggta gttgtgggcg acctcgtagg ccgcggcgat cggcaccacc gtcggcgcga
     1261 acgcgacggc cgttccccgc cagccgccac tctcgctgac ggcctccatc accacgctga
     1321 cgccgacgaa cgccgcgacg aaccccgtca gtccgagaac gtagatgaac acgctcgtcc
     1381 cgggaccggt cgagagcagg ttgcggagcc cgaacagcag gccctggaac tccggcgtgt
     1441 tcgtgaatcc gtcgaagctc accgtgtaga ccgtggcgac gacgaacgcg acgagcccga
     1501 accgctcgac ggggtacgta cagccggtcc acggcggccg gaaaacgact cggtagccgt
     1561 cgtccgtcgt gacgaacccc acgggggcga cccgtccgaa cagtcggtag agcacttcta
     1621 gggcatcggc gcggcgaaac cactcccgac cgaaggcgac cgcgccgaga accatcactg
     1681 cggcgtagcc ggcgatgacg gcggccgtcg ccgccggcga gcgtgggacg atggtgagat
     1741 tctcgaggat accgataccg acgacgaatc cgaggagtgc gggccaggag ccgagccacg
     1801 acggatagga gccgagcgca gcgatctcgt cgccttcgat ccgtgtcagc ccgtcgtaga
     1861 gcatccgcca cggcgacagc acgcgccacg ggctcccgac gaggatcgag agcaggccga
     1921 tgcccttgaa ccagacggcc cagacgaaca ccgtcgcgac gttctcggcg gcgatctgtg
     1981 ggccggtgaa gccacggacg atcgtgacga gaaatccggc gaagaagacc gctcgcgcac
     2041 cgtatcgcac gatcgtcgca acgtgtttcg ggagcacgaa cgcaggccac gttcgcccct
     2101 tctcggatcg ctcgcccgtg atcgcgagcc aggctgccgt ggcagcgacc gtgaccgcag
     2161 caccgccgaa caggagggag agcgggatcg gcgcggtgaa gcgcgagctc tggacctgat
     2221 gtgcgctcgc gacgccgacg aacgtcgtga ggccgagaag aaaagtgaac agtccccggc
     2281 gctcgttcat gccccggatc gcccgagcgc ggcaaagaag ccgttgatac gccccgttgg
     2341 tacggttctc gaatcgcccg gcccgacgcg agggcttatt cccgacgggt cgataccgac
     2401 cgcatgcaga cgcggaccgt cgtggcggtc gtccttctcg tctcggtgct cgccggaacg
     2461 gcgttcgtcg gctacagcag cctcgccgga tccagcggca cgctcgacga acgatgggtg
     2521 agcaacacgt cgacatcgat cctcggcaac caccacgctc ccgccgccgg gaaaatcgac
     2581 ggcgagggga tggtgttcgc accggtcagc ggaagcggga acggcagtag ctgccgactc
     2641 gtcgcgatga ccgccgacgg cgcgacgccg cagtggcgct accgtgtccc ggcggccaac
     2701 tgcacgatcc actcggtcgc cgatccgacg ctcgccgatt tcgacgacga cgggacgaag
     2761 gaagtcgttg ccaccacgac cgaagatctc gtcaccgcac tcgatcccca aaccggcgag
     2821 caggagttta cgtacaacct caccgactac ggttacaccc agcccctcgt cgcggacgtg
     2881 accggcgacg gggcgaacga gaccgtcgtc gtcgacttcc gcgggacggc gttcgtcctc
     2941 cggccgaacg gcagcgcggt ctggaccgag aaactcgacg cgaagacgga ggcccagccc
     3001 gcagtcgccg acttcacggg cgacaacgag agcgagatcg ccgtcggggc gggccagaaa
     3061 gtcgtgctcc tcgaccggaa cgggacggtc agatggaatc ggacgcagcc gttcgacagt
     3121 tcgatcacct ggatgacgac cgggcaggcc gacgaggacg cggcgatcga aatcgtcgcc
     3181 gcgacgttcg gcgggcgggt cgtcgcgatc gacggcgagc gcgggacggt cgagtggcaa
     3241 aaggagttcg gcgatctcgc agcggtccac gccttcgggg acggtgacgg cgatagtgct
     3301 gccgaagtct acgcgaccgc caaagacggc aaactcagga gtctcgacgc gagcgacggt
     3361 accgtcgagt ggacgaccca gctcaccgcc gaggacgtgc cgatgacgcc cccgccgggc
     3421 atgggcgacg tcgacggcga cggcgagccc gagatagtgg ccgtgacgaa cgacgggatc
     3481 gtctcggtcg tcgacccgaa atccggcgac gtccgcgcgt cgtacgagcg caacgtgccg
     3541 atctacgtcc atccgacgat cgcgaacacc gacggcgatc gagcggcgga gctgtacgcg
     3601 gtctacggcg acggccgcgt cgtcgcactc tcgtacaccg agtcgtgacg agagccacga
     3661 cgcgatgcgg atcgaccagc cagagcagtc ggtagcggct ctcgatcctc gctaacggac
     3721 ggttttccag agcgaacaca acgactatcc gaccgctcgc ccacccatcg gcatgaccga
     3781 ctacacgacc gtctcgatcc cgaaggatct cgccgaccga gtcgaggaga cgatcgaggg
     3841 gacgagcttt cagagcacct ccgatctcgt gcgctttctc ctccgcagca tcgtcatcca
     3901 acaccagaaa cagggcgaac tcaccgaggc ccagttcgac gagatcgccg agcagctccg
     3961 cgatctgggc tatctgggct agtcgagcga ctccgtcggc ggttcggcag ccacgaggtc
     4021 gagtgaccgc tcgatgccgt cgcgcgagaa gaccgcgata tcgccccgtt cccacggcgg
     4081 gaccgcgacg aacacgatgc cgtggagatc gtcggttcgt gcgagagcga gccgtccccg
     4141 tggatgtgag acgaatcgtc cctgggtctg gcccgcgggc gtgccgagat ccatcccgaa
     4201 caccgctgac accgactggc ccgcgtccgg gaagtagaag tgggtgaaca ccggtgtctc
     4261 gggcggtagc gactccgcga actcgccggc cggcgtcgtc gcgagcgcga tcgttgcctc
     4321 ctcgggttcg gcctcgcggg cgagatcgag cagcgcttcc acgagtccag cggtcgcgta
     4381 caccgcaggt cgaccggtcg cgtcgtgagc ggcagacatg ggtccagtcg tctcagttcg
     4441 cgaggaacag cctggcggtt ttcaggtaga gcgacggtgc gcggcggcgc gagcccgaca
     4501 gcgccgcgcc gagcgccggg ttcgcgtgtt cgtggacgcc cgcaccgtgg cccacgagca
     4561 cgcgctcggg ggtgaaatcc tcgaacgact gtcgcggcgg gagcagtcgc agcgccggat
     4621 ggacacccag tcgctcgctg tcggtacgca tgtactcggc cgtcccgaac gtctcagaga
     4681 cgacgagcgt gccgtcctcc tcgtggtaga gcgcgccctc ctgccacagc ggcgtggcga
     4741 ccatccgaag acggtagccc gtctcgccga gagtaccatc gaagcgctca atcggcgcgt
     4801 cgatctcgtc ggcgacgccg tccatccagg acgggacgaa caccgaagcg tcgtggcgct
     4861 cggcgaatgc ggcggcgtcg cgtttgtggc gatccaacag aacgacgacg cccccgacgt
     4921 caccgaactc ggcgagcagg tcgtcgatcc ccgcggcgtc gacgggatcg accagccaga
     4981 cgccctcgtc ggtcgcgagc gcgtggctcg cgcgctgcat ccgctcgtcg gggtaggcga
     5041 gccagccgac gccgccatcg aagcggtcga tcgcttcgta ctccgccgag ccagaaccct
     5101 tcatcggcat acccatccct cggggcggcg gcggatgagc gcatcggtgg cggatattta
     5161 tactcggcga ccgttcggga tgcatgattt cggcgctgcg ctggctcgcc ctcgaagtca
     5221 aggatatcga tcacgcgagc gcgttctacc gcgaacggct tgccctcgat accgtgcggg
     5281 agagcgagag cgaggtcgtc ctctcggccg gcgagaccga cctcgtgctc cgccggccgt
     5341 cggccatccc tcgcggggga ctccacaccc actacgcgct ctcgatcccc gcgagcgagt
     5401 acgacgactg gtacgagcag cttgcggggt cgttcgatct cgacgaacat actttcggca
     5461 gcgcgcgctc gctgtatttc tacgatcccg acgggaactg tgtcgaactc ggcgagtcgg
     5521 atggggagga gtccggcgta catgggatgt tcgaggtcgt cctcgaagtc gaggagctcg
     5581 cccgcgccga gtcgttctac accgatctcg ggatggagat cgtcgatcag gggagcgagc
     5641 gccgccggac gcggctcgcg gccgacgggt tcgccctcga actctgggaa ccccacctgg
     5701 gactggccga cgcccgtggc ggcgtccacg tcgatctcgg tgtcgccgtc ggagacccga
     5761 aagcgacgct cgacgccgtg gtggagtcgg tgcgatcggt cgaacggctc gacgacggga
     5821 ttagggttcg cgatcccgac ggccacttcg tgacgttcgt cgagggctag tcgagtcgat
     5881 cggtatcgat gtggacgccc ggtggcgtca ccaggaggaa cttccggaag tggatcagtt
     5941 cgccgtccat ctcgcggacg tcgctcgcga agccgctcgc gaggcggttc agatcgccct
     6001 cgacggcgag gacgagcacc gcgtcgtcgg cgatttcggc gatccactcc tcgctcggcg
     6061 tccgcccgtc gagcacgccg agaacgacgc gatgggtgcg ctcgccggtc tcgtcctcga
     6121 tttcgttttc gacggtctgg aggtcgagat cgaactcgct catggccgac tctcatcgcg
     6181 ccgggagaaa aatcctcgtt ttagggcgcg aacggtcagg acatcgatcg tcacggacga
     6241 atcccagttg ggcgaccgac gaatcagtcg agaaaggact ccaatcgtgc ccgatagtag
     6301 ccgtagccga tcagcagcag tccgatagcc acgaacgtgt actggatgaa ccacgccagc
     6361 ccgtcgagca gccaagcacc gacgagcacg accgccagcc cgccgaccag aaacgcgacc
     6421 cacgtgttgc tctgctccgc cattgtcctt cgatcaccac aatcgaggaa tcaacctttg
     6481 cattgtcggt cgtcgcgttg gcgtcgtgag gtggatctcg atccaagaac gcaggctgag
     6541 ttgctgttcg atgaacggcg catctcacag aaagcatata ccacaccgaa ggatagatcg
     6601 cgctatgggt ctggaaaagc tggtgcaacg aggctcactg tacgggttcg gagccggagc
     6661 agtaacgaca ggtgtcattg tgctcgtcgc cagcctgttc gatgttgcac tcggtgctgt
     6721 cgtgctcgtg ttggtcgcca ttgcgatgtt ggcgctcgtc ttgttgctcg gggctcccgg
     6781 catcggtccg ggtccggcgg tcggcgaaat gcaatccagt accggtggcg aatccggcgg
     6841 gatgcagatg ccgagtccgg tagaggcggg tggcgcgtcg agaaaccccg ccgcgatggc
     6901 agcggtcgtg ccagcaacgc ggttggagta cgtgatgtac ttcaccgggt tcggtgtggc
     6961 cgctgtcgtc gcgctcgtcg ttctcctcgg ctgaaatccc gtagcatcgg agaacgatct
     7021 cggagcggtg atcgatgatt cgttctgctt gttgcggcgc aaacacctca gcgattcgct
     7081 gttccgttat cagtcgtcgc ccgtgctcgc agccctcgcg tcggccgtct ccgtcgactg
     7141 ccgcgagaag tacgtcgcga gcgccggacc ggtgacgttg tgccagacgc taaacagcgc
     7201 gggcgggagc gccgcgagcg ggctgaagta ggccgtcgcg agcgcgaccg cgagcccgct
     7261 gttctggagg gcgacctcga aagtacacgc ccgcacccgg tcgggcgaca tcccgctcgc
     7321 acggccgacg ccgtagcccg cggcgagccc gatggcgttg tgggcgacga cagcgaccaa
     7381 caccaccgca cccgcggtca ggatgttctc gacgttcgcg ccgacgaccg ccgcgacgat
     7441 ggcgacgatg gcgacgacgc tgatcgccgg gaagacgttg agcccggccg cggcgagacg
     7501 cggtgcgtag cgatcgaggg ccagacggag cacgaagccc gcgatcactg ggataaggac
     7561 gacctgaacg atggaggtga acatctcggc gaacgtcacc tggagctgct cgcccgcgag
     7621 cgcgacgacc cacgtgggca tcacgatcgg ggcggcgagc gtcgtcacgg tcgtgatcgc
     7681 caccgagagc gcgacgtcac ccttgccgag ataggtcatc acgttcgagg ccgtgccacc
     7741 cggcgcggca cccaggagca ccacgccgat cgcgagcgcc ggcggcagcg agagcgcgat
     7801 ggtgagaccc cacgcggcga gcggcatcac gatccactgg gtgagcgcgc cgatggccac
     7861 atcgcgcggg cgctcgacga tgcgcttgaa gtcggcaggc cgcagcgtca gtcccatccc
     7921 gagcatgatg atgccgagca acggcgtgat gtacggcgaa atccaggtga acgtctccgg
     7981 agtgaggagc gccgcccccg aaaacaacag cacccacacc acgaagtagg tgctcgcgac
     8041 gttaccgatc cgttcgagcg tgtcgagcgc gctcacgccg atcctccacc ggttcgcgac
     8101 ggtcgaccgc catgcggaaa cataccgcca ccgtccgcca cagcggcgca aaaaccttcg
     8161 gacgtgaccc gttcggtgtc ggtcggtcgc gcgcgagcag cgatcggccg atttgccgtc
     8221 cgatcgagtg cgatcgtggg ccgatcgcgc cacctgcttc gtcgctggtg attgtatgat
     8281 ataaggaact atcgagggaa caaggccgtc gatggctgtc gattcgtcga tttcaccggg
     8341 tgaatccgcc cgaacggaaa ttccggagcg ataggtttat ccgtgggatg gacatccgac
     8401 cgagtacaat gtcccacaac gacacggaca cggaggattc gtcggtgacc ccggcggatc
     8461 gagttcttcc agggcaccct gggagagacg actgaagtag atacagttcg agttttcgac
     8521 acgactctgc gcgacggtga gcagtcgcca cgcacctcgt tcagctacga cgacaagcgg
     8581 gagatcgcga ccgtgctgga cgagatgggg acgcatgtca tcgaggcggg cttcccggtg
     8641 aactccgacg cggagttcga ggccgtcagc gacatcgccg agagtacggg tgtaacgacc
     8701 tgcgggctgg cacgcgtcgt cgagaaggac gtggaggcgg cgctcgattc gggcgtcgag
     8761 atggtccacg tcttcgcctc gacgagcgac gtccagctcg aagacgcgat gcacgccagt
     8821 cgcgcggaga tgaaggaacg atcggtgaac gccgtcgagc gggcaaaaga ggcgggcgtc
     8881 gaggtgatgt tctcgccgat ggacgccacg cggaccgacg aggagtatct cgtcgatgtc
     8941 gtcgaggcga ccgccgcggc gggagccgac tggatcaaca tccccgacac ctgcggggtg
     9001 gcgacgccct cccggttcgg cgagctcgtc gcccgggtct gtgaggtcgc cgacgcgcgg
     9061 gttgacgtcc acacccacga cgacttcggg ctggcgagcg cgaacgcgct cgctggcttc
     9121 gagaacggcg cggcgcaggc ccaggtgagc gtcaacggca tcggcgagcg cgccggaaac
     9181 gccgcctacg aggaggtcgt gatgagcgcc gaatcgctct acggcgtgga gtcggggatc
     9241 gacacgaccc gcatcaccga actctctcga ctggtcgagc gcgcgagcga gatcgagact
     9301 cccggcaaca agccggtggt cgggcagaac gccttcagcc acgagtcggg cattcacgcg
     9361 gccggcgtga tcgagaactc cgacacgttc gagccgggtg tgatgacccc cgagatggtc
     9421 ggcgcgcagc gcgagctcgt cctcggcaaa cacaccggga cgcactcggt gcgcgagcgg
     9481 ctgcacgagg ccggcttcga cccgaccgac gacgaggtac gcgagtgtac ccggcgggtg
     9541 aaggagttcg gcgcggagaa agagcgcgtg acgatgagcg tgctcgaacg gttcgcccgc
     9601 gaggtcggca tcgagcagat cggcaagacg gaggtcaacg cctgagcatg accccgtcgc
     9661 acgcctccac ccaccagcca cgggtagcgc ccgaaccccg cgttcggggc aacgtttgca
     9721 cggcgcgcaa aggttataac cgatcccctg gtggggacga caacgatgac gcgaccgacc
     9781 accgcccgag ggacgcgaac tcggagcggc gcactcggcg cgcgcggccg cattattgta
     9841 ggggtttagc ccctacagag ccacttcctt cgaccccgac gcgtttcgca cggcgaacag
     9901 cacgcgcgac agccgacgac acaccgatga ccacacgaga accagcaccg accacacgcg
     9961 acagccgagc ggcatcgacg acgaacgacg gaggcgaccg atgagcgagg gccagcagac
    10021 cccacagacg ggcgagcccg aggacgccga accggagacg gtcgaggcga ccgaagccag
    10081 cgagcgcccc gtgaccagcg gtgcggagtc ggtggcgcgg gcgctcgaac ggacgggcgt
    10141 cgagacgctg ttcggcgtcc agggcggggc catcatgccg gtctacgacg cgctgtacga
    10201 ctcgccgctc gaccacgtga cgatggcaca cgaacagggt gcggcccacg cggccgacgc
    10261 cttcggcatc gtctcgggcg agccgggcat ctgtctggcg acctccgggc cgggcgcgac
    10321 gaatctcgtg accgggctcg cggacgcctc gatggactcc gacccattgg tggcgctcac
    10381 cggccaggtc ccctccgcaa tggtcgggac cgacgccttc caggagaccg acaccaccgg
    10441 tgttacgaac ccggtgacga aggagaacta cttcgccggc gacgtcgact cggtcggcga
    10501 cacggtcggc gaggcgttcg cgctcgcgga tgccggccga cagggcccca cactggtcga
    10561 tctcccgaag gacatcacga ccgggccgac cgagagcgag ccggctgcag gaacagcgcc
    10621 cgagacgtac gacccgcccg agcgggccga cgacgaggcg gtcgaaacgg ccgccagcgt
    10681 gctcgcgcac gccgataaac ccgtgatcct cgcgggcggc ggtgtcatca agggcgaggc
    10741 ctgtgacgaa ctcagggaat tcgccaccga gtacggaatc ccggtggtga cgacgatgcc
    10801 cgcggtaggc gcgttccccg agggccacga cctcgcgatg gagatggcgg ggatgcacgg
    10861 cacgggctac gcgaacatgg ccatcacgca ctgtgatgcc atgttcgcgg ttggaacgcg
    10921 attcgacgac cgcctgacgg gtggcgtcga gacgttcgct ccgggggccg agatcatcca
    10981 cgccgacatc gacgcggcgg agatctcgaa gaacatcgcg gccgactacc cactcctggg
    11041 tgaggcgagc gtcgtcatcg agcaggtgca cgaggcgatg gccgacgagc gcgcggcgga
    11101 catggcggcc accggcgagc gcttccagga atgggtcgag cagtgccagc agtggcagac
    11161 cgactacccg atggactacc cgatggacga agatgggccg ctgaaaccgc agttcgtcgt
    11221 cgaaaccgtg gacacggcga ccgacgacga caccatcgtc accacgggcg tcggccagca
    11281 ccagatgtgg gcggtccagt actggacgta caccgagccg cggacgtggg tgtcgtccca
    11341 cgggctgggc acgatgggct acgggctgcc gtcggccatc ggcgcgcgat tcgccgcgga
    11401 cgacgaccag tcggtggtct gtttcgacgg cgacgggtcg ttcctgatga cgctgcagga
    11461 gctggcggtc gccgtccgcg aggacctcga catcaccgtg ttcatcctca acaacgaggc
    11521 cgtcggcatg gtgcgccagt ggcaggacag cttccacggt ggccggcgga tggcctcgga
    11581 gtacccctgg gtgcccgatt tcgccgcgct cgccgaggcg ttcggcgcgc gcgggttccg
    11641 gatggagggc cacgacgagg ttgccgacgt cgtcgaggac gcgctggcct acgacggccc
    11701 gtcggtcgtc gacgcgttca tcgacccgac cgaggacgtc tatccgatgg ttcccagtgg
    11761 cggatcgaac ggccagttcg tgctggcgga ggagcagcta tgaccgaggg tctccaggga
    11821 ccggcccccg aggagcgtcc ccagccgtcg gggcggcgca acgcgcaggg catccggatc
    11881 gatcccgaga tggaggccgt gcacgacccg cggcgcacga cgttatcggc gctcgtccag
    11941 aacgagccgg gcgtgctggc gaagatctcg ggactggtct cgcgtcggca gttcaacatc
    12001 gaatccttga ccgtcggcac gacgaccaac cccgaaacct cgcgcgtgac gctggtcatc
    12061 gaggagcccg aaccgggcat tcgccaggtc gaaaagcaac tcgaaaagct cgtcaacgtc
    12121 atctcggtgc gcgagctcgg cgacgacgcc atccgccgtg agctggtggt gttgaaggtc
    12181 cacggcgagg agccggacaa ggtcaacgcc atcaccgaca tgtacggcgg cgagacgctc
    12241 gatgccgggc cgcgcaccat cacggtgcag atcaccggcg acgagcagaa gatcgacgac
    12301 gcgatcgacg ctttccgaca gttcggtatc cgcgagctcg ccagaaccgg tcagacggcg
    12361 ctcgcgcgcg gtgaggagtg gacgacacac gcggaagagg agcggtacga acgaacgcag
    12421 gtacgacaat gacagaacac gcaacgatct actacgacga cgacgcagac agcaccgcac
    12481 tcgaaggcaa aactgtagcc gtcatgggct acggctcaca gggtcacgcc cacgcgcaga
    12541 acctcgccga cagcggggtc gacgtggtcg ttggcctccg agagaattcg agctcgcgcg
    12601 acgccgtccg cgaggacggt ctcgacgtgg cgacgcccgt ggaggccgcc gcacgcgcgg
    12661 acgtcgtctc gatgctcgtt cccgatactg tgcagcccgc agtatacgat gacatcgccg
    12721 acgaactcga cgccggcgac acactccagt tcgcccacgg gttcaacatc cacttcgggc
    12781 agatcgagcc ggccgacgac gtggacgtga cgatggtcgc gccgaagggc ccgggccaca
    12841 tcgtccgccg ggactacgag cgcggcgagg gaactcccgg actgctcgcg gtctaccagg
    12901 acgcgacggg cgaggcagcc gacgaagcgc tcgcgtacgc gcaggggatc ggctgtaccc
    12961 gtgcgggcgt cgtcgagacc agtttccgcg aggagaccga gaccgacctg ttcggcgagc
    13021 aggcggtgct ttgcggtggc gtgacgagcc tgatcaagca ggcctacgag acgctcgtcg
    13081 atgccggcta cagtccggag atggcctact tcgagtgtct caacgagatg aaactgatcg
    13141 tcgatctgat gtacgagggc gggctcggcg acatgtggga ctcggtctcc gatacggccg
    13201 agttcggtgg tctcaccaag ggcgacgtcg tggtcgacga gcacgcccgc gagaacatgg
    13261 aggaagtcct cgacgacgtt caatcggggg cgttcgcccg cgagtggatc gcggagaacc
    13321 aggccaaccg acccgcatac cgccagctgc gacaggccga gaaggatcac gagatcgagg
    13381 aggttggcga gcgcctgcgt gacctgttcg cgtgggccga ggagtccgaa tcgaacgagg
    13441 aacgaaacga aaccgaacga gtgcaagcag atgactgata cacgacacga acgagcgacg
    13501 acgatgagca cggtcgatca cacccatccc gacaccggac gaccgttcgg cgacgccgtg
    13561 gtctaccagc gtgggccggc cgtcgcggcc gacggcggtg agagaaccaa cggctgtctc
    13621 ttatacacat ctctgatg
//
