LOCUS       NZ_CP070290.1          24598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP070290.1 Escherichia albertii strain Sample 167 chromosome,
            complete genome.
ACCESSION   NZ_CP070290
VERSION     NZ_CP070290.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:11:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4323903
            Orig. end    :: 4348501
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24598
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[4333903:4338501]"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14598
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
     cand_cluster    1..24598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /kind="single"
                     /product="Formate_dehydrogenase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Formate_dehydrogenase"
                     /region_number="23"
                     /rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /tool="gutsmash"
     CDS             complement(800..1762)
                     /locus_tag="ctg1_3989"
                     /transl_table=11
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGL
                     YEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGD
                     GSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQR
                     ISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSRDDLVNEIKAGIAKGKKHAIVAIT
                     EHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIELLLAGYG
                     GRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     CDS             complement(1944..2846)
                     /locus_tag="ctg1_3990"
                     /transl_table=11
                     /translation="MNQSYGRLVSRAAVAATAMASLLLLIKIFAWWYTGSVSILAALVD
                     SLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQH
                     LVSPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGA
                     ILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAIQSLLDRALPDEERQEIFDIV
                     TSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVI
                     IHQDPCSVVPRESKKSTLS"
     CDS             complement(2995..3495)
                     /locus_tag="ctg1_3991"
                     /transl_table=11
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELAQRSTQSHM
                     FDGISLTEHQRQQMRDLMQQARHEQPPVNVSEMETMHRLVTAENFDENAVRAQAEKMAK
                     EQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSSSNS
                     RSQ"
     CDS             3645..4346
                     /locus_tag="ctg1_3992"
                     /transl_table=11
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALELLDDSI
                     DLLLLDVMMPKKNGIDTLKTLRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPFND
                     RELVARIRAILRRSHWSEQQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGTEF
                     TLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTL
                     RGRGYLMVSAS"
     CDS             4343..5716
                     /locus_tag="ctg1_3993"
                     /transl_table=11
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQRQ
                     GLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERNEMQI
                     IRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLLFDR
                     PLLLLIVTMLVSSPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEFLAAG
                     ASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELERIETEA
                     QRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSFTVNFPPGP
                     WPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPADREQI
                     FRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKADDSPLGGLRLVIWLPLYKRS"
     CDS             complement(5902..6108)
                     /locus_tag="ctg1_3994"
                     /transl_table=11
                     /translation="MEHIENITEIRAAVKHILFEEYHLESVNDIFDLDGETLAEMYEQF
                     KCVMEEYGLDGEDVESILNGIDG"
     CDS             complement(6128..6811)
                     /locus_tag="ctg1_3995"
                     /transl_table=11
                     /translation="MHYPVDVYTGKIQDYPQSRPSAIAKIQVDGELVLTELGLEGDEQA
                     EKKIHGGPDRALCHYPREHYLYWAREFPEQADLFVAPAFGENLSTEGLTESNVYIGDIF
                     RWGEALIQVTQPRSPCFKLNYHFGISDMAQLMQNAGKIGWLYSVIAPGKVSADAPLELV
                     SRVSDVTVQEAIAIAWHMPFDDEQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFSRRLW
                     GSSKN"
     CDS             complement(6881..7501)
                     /locus_tag="ctg1_3996"
                     /transl_table=11
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQAYVNNANAALES
                     LPEFANLSVEELITKLEQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAAIE
                     RDFGSVDNFKAEFEKAAASRFGSGWAWLVQKGDKLAVVSTANQDSPLMGEAISGASGFP
                     ILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     CDS             complement(7765..8820)
                     /locus_tag="ctg1_3997"
                     /transl_table=11
                     /translation="MKRNLLSSAIIVAVMALSVTGCDDKKAETESSPSANNQPAAPTTE
                     SKPTEKPAAKAEAKSEASAQPVVDEQAVYDEKMAVYIKCFNELQLPVQRSLSRYADWLK
                     DFKQGPTGKESIVYGIYSISEISLTGCEKGMKRVAALTPALEPIDGVALDYINAAVALG
                     NTINEMDKYYTQENYKDDAFAKGKILHQTLLKNIEAFQPVAESYRTAIEEINDRRQLAE
                     LKNIEQREGKNFHYYSLAVMISAKKINGLISQEKFDTEMAMKKVAELETLVAQVKEADK
                     GGMNFPFINSAGEYQLAAKKYVRRVRDNVPYSEGDKELLQDPGSSWMVEASYPAALNEY
                     NEMVGDYNRLR"
     CDS             complement(8974..9807)
                     /locus_tag="ctg1_3998"
                     /transl_table=11
                     /translation="VKKTQQKEIINVTNVTGVRQIEVWRRDDLQHPRLDEVAEEVPVAL
                     VYNGISHVVMMASPKDLERFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRR
                     FMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPV
                     GQLTGCTHAAAWILPSGELAGGHEDVGRHVALDKLLGRRAQEGENWQQGAVLVSSRASY
                     EMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLKC"
     CDS             10001..10588
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdop_Fe4S4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3999"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 1e-19, bitscore:
                     68.3, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 6.6e-07, bitscore:
                     26.6, seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTRE
                     TRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFIHS
                     ESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLSTGM
                     LCASASSNETGYLTQKFSRALGMLAVDNQARV"
     CDS             10637..13051
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4000"
                     /sec_met_domain="Molybdopterin (E-value: 2.9e-21, bitscore:
                     73.9, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.5e-16,
                     bitscore: 58.4, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHWVDIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIV
                     IDPRFTRTAAVADYYAPIRSGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDY
                     GFEDGLFTGYDAEKRKYDKSTWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDV
                     VENICGTPKDAFLKVCEYIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGN
                     MGMAGGGVNALRGHSNIQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEG
                     QVNYWGNYPKFFVSMMKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGY
                     ICQGFNPVASFPNKNKVIGCLSKLKFLVTIDPLNTETSNFWQNHGEMNDVDPTKIQTEV
                     FRLPSTCFAEENGSIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGA
                     NPDQVLNMTWNYAIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRD
                     DGTTSCGCWIFAGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQ
                     GNPWDPKRQLLKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFAIDKMAEGPF
                     PEHYEPFETPLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWT
                     KHALLNAILQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANG
                     KDIDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     CDS             13064..13966
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Form-deh_trans"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 25.7; E-value:
                     4.5e-08)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4001"
                     /sec_met_domain="Fer4 (E-value: 1.4e-05, bitscore: 22.7,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_11 (E-value: 3.1e-25, bitscore: 86.2,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0083, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Form-deh_trans (E-value: 1.3e-20,
                     bitscore: 70.9, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKAC
                     QVACSEWNDIRDTVGNNVGVYDNPNDLSAKSWTVMRFSEVEQDDKLEWLIRKDGCMHCA
                     DPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFNVPRLNPEDNRVYKCTLC
                     VDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGT
                     HVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGP
                     NRADEEENNLHEEKDEERK"
     CDS             13963..14598
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Ni_hydr_CYTB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4002"
                     /sec_met_domain="Ni_hydr_CYTB (E-value: 9.4e-23, bitscore:
                     78.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGMGFLFPSFNWLMQ
                     IMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVGDT
                     GRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVALIVV
                     IMVHIYAALWVKGTITAMVEGWVTNAWAKKHHPRWYREVRKTTEKKAE"
     CDS             14595..15524
                     /locus_tag="ctg1_4003"
                     /transl_table=11
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELA
                     ENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQ
                     KLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAA
                     LSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEW
                     HVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKIFYQEKDPKVEAVADDLA
                     SLVLDARMEQEGYARSSINPFLFPGEGE"
     CDS             16430..17275
                     /locus_tag="ctg1_4004"
                     /transl_table=11
                     /translation="MKINKFISHKKMRLFFAQEIKAISRWPYGTEGIELSRLPGDVRYN
                     LIPPEAPWHIDVNDDYMEFRRSPFWMVSGEVFMGFILSLLSISFLLVTVSSFFALGYSP
                     HLFFAYVITAFFCIAVLPSAAKIAFLTPHYLPIRFNRKTQKIYVADLKIEGGIFFRKIK
                     LTFREMDWKDVEAWSVSRRFAKNSPYFGLHLVENTSNEISLLKQTRMYATRAPWTNEEW
                     ERQRSYIPKIWSYCQHYMAFMPVPDESTKPKPFVFLKNNWLFKWPEEMDARSKSSGDTV
                     "
     CDS             complement(17436..17768)
                     /locus_tag="ctg1_4005"
                     /transl_table=11
                     /translation="MKILRLSKDSPPKPDEEIWSFGLFIVGFVVTVFMMNKILSIDLNY
                     IIRIAFIGVPAFIVGCLLVYLQEVIRIIALLIETVLFLIEILCSLAFICFVIYMVCELV
                     YTIVRS"
     CDS             complement(18041..19855)
                     /locus_tag="ctg1_4006"
                     /transl_table=11
                     /translation="MVVDINLIKQKYYSVINLEKLRSSNESQKQTLLNDFSHRLKMDAQ
                     EQLSSCVNELKHGLSSNNEYSLFKNREGSLWKRTVPESAALAMTGTVYKLFGSRLLNDC
                     GQLDKDLLEMAMQMVYGKDMVTKSGEILIDAQLNKEGVLQSKHYLLDVGEIKNNYDIDL
                     FVNTSSVNQTYLHDKSISDITILYDTLDNVPSVVAECTGKNNQFKVEATSPQERREKIQ
                     KMCDDMRSNAFMFDHTTKTAGNIEHRLQLKFLVDSRPSITNKYPAGEVGSDILDLPVNV
                     WQAQFNININSAVEKVSTIILCAVQQDQYAARQVMGGIMKNLPKNNKPKTVLLDLRFLS
                     AIKQMVVSGSEKPLFVKHTEMIREACEELSQPVEYIPLHCEAHSHRSVAFAKTVAAPIM
                     ATGVGAALMYATSSGPYYARSMSSSPEIEMVKSRMADLFNQMDNVAREKYLPIFRKWNE
                     MVGELNYERNSVPFASLTNILATAINQSHNGDTNVVVMMGCKSAKDRTTSVVLGNSLLQ
                     TLIEKRLAEHTTIETLFDKEGYFSCESLTTEELVMLKDLFDIRILHIANKFNVGLEGNI
                     NTDVLQDSFFKNVDFIHKSNAYTGSMSN"
     CDS             complement(20316..21257)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4007"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.9e-14,
                     bitscore: 50.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAHH
                     QMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGVKR
                     VTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQLQQ
                     AWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWL
                     MLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIF
                     GDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     CDS             complement(21302..21739)
                     /locus_tag="ctg1_4008"
                     /transl_table=11
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRL
                     CERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGAPPDRAEA
                     LYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     CDS             complement(21736..22608)
                     /locus_tag="ctg1_4009"
                     /transl_table=11
                     /translation="MLKNIQDKARHHTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLL
                     SLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAV
                     GACGLIVTALLLMYSIDSALNAIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSY
                     LLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFE
                     AGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQA
                     AEQEEDDEP"
     CDS             complement(22602..23201)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4010"
                     /sec_met_domain="HAD_2 (E-value: 7.6e-13, bitscore: 46.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYIFDLGNVIVDIDFNRVLGTWSDLTRIPLATLKKSFHMGEAFH
                     QHERGEISDEAFAEVLCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHRVV
                     VLSNTNRLHTTFWPEEYPEIRDAADHIYLSQELGMRKPEARIYQHVLQAEGFSPDDTVF
                     FDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     CDS             complement(23300..24085)
                     /locus_tag="ctg1_4011"
                     /transl_table=11
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDI
                     RKLSEQGLITRHHGGAGRASSVVNMAFEQREVSQTEEKKAIAEAVADYIPDGSTIFITI
                     GTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGILRSHNSGIIGPSAAS
                     FVADFRADYLVASVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAV
                     EIGNVAQVTALFTDEEPPAALKSRLQDSQIEIILPQDDA"
ORIGIN
        1 cccaggcagc cagatagttc cagcgagcgc cgccagagct ttttgggttt ggcgtaatca
       61 ctgaaacacc cgatttaacc aaatcgttcc agtcgtgaat ttgcttcgga ttacccttgc
      121 gcaccagaaa tacaatggtg gaagtgtatg gcgcagagtt atctggcagg cgcttgatcc
      181 agtttttatc aatacgacca cgttctgcaa tagcatccac gtcataagcc agcgccagcg
      241 taacgacatc tgcgtcaata ccattaatta ccgacgtcgc ttgcttacct gaaccaccgt
      301 gcgactggcg aattaccacg ttatcgcccg tttgctgttt ccagtgggcg ctgaacgctt
      361 tgttgtactg ctcatacaac tcgcgtgttg gatcatacga aacgttaaga agctgaatat
      421 cctttgccat aacgctggtc gctgccagca aaaatgttaa ccctacgccc cacgtgttca
      481 tcgcccggct ctcttatgtt gtgttgtgat gatcaaagcg tgccagaaag ggcataaaac
      541 attaaagaat aaaaaaagat tgggtataac ttgtaggtat atatcggggg ttaaaaaggc
      601 ggaagaaatc cgcctcatat tgctgacaaa gtacgctttg tccatgtcgg atgcggcgtc
      661 aacgccttat caggcctaca aaatcttgca aattcaataa attgcagaat tcatgtaggc
      721 ctgataagcg gagtgcatca ggcatttttg cttctgtcat cggtttcagg ctaaagaaat
      781 ctgccttttt ccgaaatcat taatacagtt ttttcgcgca gtccagccag tcgcctttga
      841 acggacgctt catgttttcg atagcgtcaa tgatgtcatg gtgaaccagt tgctcgttct
      901 gaatacctac gcagcgaccg ccataaccag ccagcagcaa ctcaatcgca taagcgccca
      961 tacgggaagc cagaatacgg tcataaggta ccggggaacc gccgcgctga atgtggccca
     1021 gtacagttgc acgagtttca cgaccggttt ctttttcgat aaagtgcgcc agttcgtcga
     1081 catcgcacat gtgttcggta atcgccacaa tcgcgtgttt tttacctttc gcgatacccg
     1141 ctttgatttc atttaccagg tcgtcacggc tgaattcaac ttctggaacc acaacgaatt
     1201 cacaaccacc agcaatagcc gcagccagcg tcagatcgcc acagtaacga cccatcactt
     1261 ccaccacgga aatacgctgg tgagaagaag aggtatcacg caaacggtcg atagcttcta
     1321 caacagtgct cagcgcagtg aagaaaccga tggtgtagtc agtgcctttg atatcgttat
     1381 cgatggtgcc cggcagaccg atgcacggga agcccatttc tgtcagacgc attgccccca
     1441 tataggaacc atcaccacca ataacgacca gtgcatcaat tccacgtttt ttcaggtttt
     1501 cgatagccac ggcgcggatg ttctcgtcgc ggaattccgg gaagcgtgca gaaccgagga
     1561 acgtaccgcc acggttgatc atgtcagaca cgctataacg gtctagctgt accatgcggt
     1621 cttcatacag acccagatag ccgtcataaa tgcccataac ttccagacct tctgtcagcg
     1681 cagaacgaac aaccccgcga attgcggcgt tcatgcctgg cgcatcaccg ccgcttgtca
     1741 acacaccgat tttcttaatc atgactacct ctgaactttg gaatgcaaaa tgaaatctgt
     1801 tgccggaagt cttcttgcac atcgaagtga tccaacgaat gtacaaatag tataacaatc
     1861 acttcctgct gaattgattc aggtcaggcc aaatggcggt attttataca caaaatgcga
     1921 gtctggctct ctttttatac cgatcatgaa agcgtagact ttttactctc cctgggtacg
     1981 acggagcaag gatcctgatg gataatcaca tccgatcccg gaaaacgccg taaaatagcc
     2041 tgctctacct gatccgccac catatgtgcc tgaaccaaag gcagagagtc ttccatttcc
     2101 aaatgaatct gaataaagcg agtcggccct gactgccgcg tgcgaagatc gtgagcaccg
     2161 ctaactcccg gccaggaagt cacgatatca aaaatttcct gtcgctcctc atcgggcagc
     2221 gcgcgatcca gcaatgactg tatcgcctca taccccatgc gtaacgcgct atataaaata
     2281 tagatgccga ttcccaaagc aaacaaggca tcagcacgat gccagccata ccaggacaaa
     2341 cccagcgcca gcaaaatcgc gccgttcatc ataacatcag actgataatg tagcatatct
     2401 gcccgcacag cctgactttg cgtcctgcgc acgacccaac gctgaaacga gacaagtatg
     2461 atcgtgcaga ttaacgccac gatagtcacg ataactccaa ccccaggatc cgtcatcggc
     2521 gttggagaaa ccaagtgctg aatgccggtc aaaaacaaaa acagcgccga accggagata
     2581 aacatgcttt gcgccagcgc cgcgagggac tcagctttac cgtggccaaa cgagtgattg
     2641 tcgtcggcag gctgcagcga atatcgcacc accagcaaat tcgtcagcga cgcgccgata
     2701 tcaactaacg aatcgaccaa cgcggcaaga atactcaccg aaccggtata ccaccatgca
     2761 aaaattttaa tcagcaatag cagcgaagcc atcgccgtcg cagcaactgc cgcccgactg
     2821 accagccgtc cataagattg attcataaat actcccgcta tcaactgacg gtagtataac
     2881 ggatgcaaat catctgcaat gcattaagca acaggcaaat taaggataaa aaaaaccccc
     2941 acatcatgtg ggggaagaca gggatggtgt ctatggcaag gaaaacaggg tttactactg
     3001 ggaacgtgag ttgctactac tcaatagctt caacgatgaa cttttttgcc attgcgtcac
     3061 gtcgcgcaac tgttccattc gttgttgatg tttctcattt aaaaccgctt gctgctctgg
     3121 cgttagcagg cgatacattt ggttgcggac tttagccatt tcaacctgac gagcgatctg
     3181 ctctttcgcc attttttctg cctgagcacg cacagcgttt tcatcaaaat tttctgcagt
     3241 gacaaggcga tgcattgtct ccatttcgct aacattaaca ggaggctgtt catgtcgggc
     3301 ctgctgcata agatctcgca tctgctgacg ctgatgttcg gttaaactta tgccgtcgaa
     3361 catatggctc tgcgtactgc gctgcgcaag ttcttcgccc ggatgccagt tatcgcctga
     3421 accgacttca gcagcgtggc ttaatgaact gactgccagc gttgaggcca tgacggcagc
     3481 ggtaactatg cgcatcattt gctcccaaaa tctttctgtc gcgattcaac gatagagagt
     3541 ttacgattca ggctgcaaac atgcgtcagg gggtgtaaaa caacgtaaag tcatggatca
     3601 gcgacgtctg atgacgtaat ttctgcctcg gaggtattta aacaatgaat aaaatcctgt
     3661 tagttgatga tgaccgagag ctgacttccc tgttaaagga gctgctcgaa atggaaggct
     3721 tcaacgtgat tgttgcccac gacggggaac aagcgcttga gcttctggac gacagcattg
     3781 atttactttt gcttgatgta atgatgccga agaaaaatgg catcgatacg ctaaaaacac
     3841 ttcgccagac acaccagacg cctgtcatta tgttgacggc acgcggtagt gaacttgatc
     3901 gcgttctcgg ccttgagctg ggcgcagatg actatcttcc aaaaccattt aatgaccgtg
     3961 agctggtcgc ccgtattcgc gcgattctgc gccgttcgca ctggagcgag cagcaacagc
     4021 aaaacaacga caacggttct ccgacactgg aagtcgatgc gttagtactg aatccggggc
     4081 gtcaggaagc cagcttcgac gggcaaacgc tggagttaac cggcaccgaa tttaccctgc
     4141 tctatttatt ggcgcagcat ctgggtcagg tcgtttcacg tgaacattta agccaggaag
     4201 tgctgggcaa acgcctgacg cctttcgacc gcgctatcga tatgcatatc tccaacctgc
     4261 gtcgtaaatt gccagatcgt aaagacggtc atccgtggtt taaaacgttg cgtggtcgcg
     4321 gctatctgat ggtctccgct tcatgatagg cagcttaact gcgcgcatct tcgccatctt
     4381 ctggctgacg ctggcgctgg tgttgatgtt ggtcttgatg ttacctaagc tcgattcacg
     4441 ccagatgacc gagcttctgg atagcgagca gcgtcagggg ctgatgattg agcagcatgt
     4501 cgaagcagag ctggcgaacg atccgcccaa cgatttaatg tggtggcgtc gcctgttccg
     4561 tgccattgat aagtgggcgc ctccgggcca gcgtttatta ctggtaacca ccgaagggcg
     4621 cgtgatcggt gctgaacgca acgaaatgca gatcattcgc aactttattg gtcaggcaga
     4681 taacgccgat cacccgcaga agaaaaagta tggtcgcgtg gaacttgtcg ggccattctc
     4741 cgtgcgcgac ggcgaagata attaccagct ctatctgatc cgcccggcca gcagttctca
     4801 atccgatttt attaacttac tgttcgaccg tcctctatta ctgcttattg tcaccatgtt
     4861 ggtcagttca ccgctgctgt tgtggttggc ctggagtctg gcgaaaccgg cgcgtaagct
     4921 gaaaaacgct gccgatgagg tcgcccaggg gaacttacgc cagcacccgg aactggaagc
     4981 aggaccgcaa gaattccttg ccgcaggcgc cagttttaac cagatggtca ccgcactgga
     5041 gcgcatgatg acctcccagc agcgcttgct ctctgacatt tctcacgaac tacgcacgcc
     5101 gttgacgcgc ctgcaactgg gtacggcgtt actgcgtcgt cgtagcggcg aaagcaagga
     5161 actggaacgt attgaaaccg aagcccaacg gctggatagc atgatcaacg acctgttggt
     5221 gatgtcacgt aatcagcaaa agaacgcgct ggtgagcgag accatcaaag ccaaccagtt
     5281 atggagtgaa gtgctggata atgcggcgtt cgaggcagaa caaatgggca aatcgtttac
     5341 ggttaatttc ccgccagggc catggccgct gtacggtaac ccgaatgctc tggaaagtgc
     5401 gctggaaaac atcgttcgca acgcgctgcg ttattctcat acgaagattg aagtgggctt
     5461 cgcggtagat aaagacggta tcaccattac ggtggatgac gatggcccgg gcgttagccc
     5521 ggcagatcgc gagcagattt tccgtccatt ctatcgtact gacgaagcgc gcgatcgcga
     5581 atctggcggt acgggcctgg gtctggcgat tgttgaaacc gccattcagc agcaccgtgg
     5641 ttgggtgaaa gccgacgata gcccgctggg cggtttacgg ctggtgattt ggctgccgtt
     5701 gtataaacgg tcataacgtc aaccttcagg taaaaaatgc ctgatgcact acgcttatca
     5761 ggcctacaaa acctgcggaa tttattgatt ttgtaggccg gataaggcgt ttacgccgca
     5821 tccgacgttt gagcatggag cctgatgcga cgctggtcgc gtcttatcag gcctactctc
     5881 tacgatgcca gtttcattaa gtcagccatc aatcccgtta agaatactct ccacgtcttc
     5941 accatccaga ccgtattctt ccatcacaca tttaaattgt tcatacattt cagccagtgt
     6001 ttcgccgtct aagtcgaaaa tatcattgac cgattccagg tgatactctt caaacagaat
     6061 atgcttaact gcagcgcgta tttccgtaat attttcaata tgttccatct tccctctcta
     6121 taatccatta gtttttactg cttccccaca accgccggga aaaatcttca atcttgccgc
     6181 taagacgccg cttctgcatc gtccgcgtcc agcttttcga tagccccgca gccgagagca
     6241 aacggtgata ttgctcgtca tcaaacggca tatgccacgc gatagcaatc gcctcctgca
     6301 ccgtcacatc gctaacgcgt gagaccagct ccagcggcgc atcggcagac acctttcctg
     6361 gcgctatcac actatacagc cagccaattt tcccggcatt ctgcatcaac tgcgccatat
     6421 cgctaatacc gaaatgataa ttgagtttaa aacatggcga acgcggctgg gtgacctgaa
     6481 tcagcgcctc tccccagcga aaaatatcac caatatagac attactctcg gtcaggcctt
     6541 cggttgacaa gttttcccca aaggctggag ccacaaacag atccgcctgc tccgggaatt
     6601 cccgcgccca ataaagataa tgttcacgag gatagtgaca cagcgccctg tctggcccgc
     6661 cgtggatttt tttctctgcc tgctcatcgc cttccaggcc cagttccgtc agcaccagtt
     6721 cgccatcgac ctggattttc gcaatcgcgc tggggcgact ttgcggataa tcctgaattt
     6781 tgcctgtgta tacatcaacg ggataatgca tctgttttct ccttcgcaga tacaaaaaag
     6841 cgagccatca gactcgcttc tcacaggcgt ttatgcaacc ttattttttc gccgcgaaac
     6901 gtgccgcagc ttcatcccag ttcaccacgt tccagaactc tttgatgtag tccgggcgac
     6961 ggttctggaa tttcaggtag taagcgtgtt cccaaacgtc cagccccaga atcgggaaac
     7021 cggaagcgcc agaaatggct tcacccatca gcggggagtc ctggttagca gtagaaacta
     7081 ccgccagttt atcgcctttt tgcaccagcc atgcccagcc ggaaccaaag cgggaagccg
     7141 ccgctttttc aaattctgct ttgaaattat cgacggaacc gaaatcacgt tcgatagccg
     7201 ctttcagatc accctgcaga gtggtgcctt ttttcagacc tttccagaac aggctatggt
     7261 tagcgtgacc gcccgcgtta ttgcgcagca cggttttctt gtctgctggc agctgttcca
     7321 gtttggtaat caactcttca accgacagat tggcgaactc tggcagactt tccagcgccg
     7381 cgttggcgtt gttgacgtag gcctgatgat gtttggtgtg atggatttcc atggtctgct
     7441 tatcgaagtg tggttccagg gcatcgtaag catacggcag ggatggcagg gtatagctca
     7501 ttttcatctc cagtattgtc gggcggccga ttgttaatgc cgcgtaagca gttggttcat
     7561 tatagttaat taaatgatat tgaaaatgat tatcaatgcc gcacttttca taaggatatg
     7621 gttttgcagg gaaatgcctg agatatgcgc caaatcatct acttaatgtc atgagactaa
     7681 cggaatagcg tcactccgcc agtgagggaa tattatcgga tgcgtcacat ccgacattac
     7741 aacgctaatc caaaaaacaa actcttatcg cagacggtta taatcgccga ccatttcatt
     7801 gtattcgttt aatgccgccg ggtaagaggc ttctaccatc caacttgagc caggatcctg
     7861 aagcagctct ttatcccctt cagaatacgg gacgttatct ctgacgcggc gaacatattt
     7921 cttagccgca agttgatatt cgcctgccga gttaataaaa ggaaaattca tgccgccttt
     7981 atctgcttcc ttgacctgcg cgaccaatgt ttccagttcg gcaactttct tcattgccat
     8041 ttccgtatca aacttttctt gtgaaattaa cccattaatt tttttagctg aaatcatgac
     8101 agccagtgaa tagtagtgga aattcttccc ttctcgttgc tcaatatttt tcagttcagc
     8161 aagctggcgc cgatcattaa tttcttcaat agccgtacga taagactccg caactggctg
     8221 gaaggcttcg atattcttca acaacgtctg gtgaagaatt ttccctttag caaacgcgtc
     8281 gtctttataa ttttcctgag tgtaatattt atccatttca ttaatggtat tacccaacgc
     8341 cacagcagca ttaatatagt ccaacgcaac accatcaata ggttcaagag ccggtgttaa
     8401 tgccgcaaca cgcttcatcc ctttttcaca gccagtaagg cttatttcac tgatactata
     8461 gatcccataa acaatgctct ctttacctgt cggcccctgt ttaaaatctt ttaaccaatc
     8521 agcgtaacgc gacagactac gttgtacagg aagctgtaat tcattgaaac atttgatgta
     8581 gacagccatc ttctcatcat acacagcttg ctcatcgacc acaggttgcg cagacgcctc
     8641 cgatttagcc tcagcttttg ctgccggttt ttcagtcggt tttgattcag ttgtgggagc
     8701 ggcgggttga ttattggcgg acggggagct ttctgtttca gcttttttat catcacatcc
     8761 agtgacactg agggccatta cggcgacaat aatagccgaa gataataaat tccttttcat
     8821 ttaattgcct tataaataga tgaataagag tgcgaatatg ataaagggaa aaaggaaata
     8881 ccactacgca agatttattt ataaataaat cgataaaatt cacaaaatga ataagtcctg
     8941 caatgcaata tacaattgca ggacttaatt taattaacac ttcaaccttt gtggatgggt
     9001 ataaaccgtc gccctgcccg gtttgcaaaa acccaccagc gtcagattac agcgttcagc
     9061 cacttctaca gcaagcgtgg tcgcagcaga cacagcaaac aaaatctcta cgccgcacat
     9121 cgccgacttt tgcaccatct cataactggc ccggctggaa accagcactg cgccttgctg
     9181 ccagttttca ccttcttgcg cccgacggcc tagtaattta tccagcgcca catggcggcc
     9241 cacgtcttca tgtccgcccg ccagctcacc ggaaggtaat atccaggccg cagcgtgagt
     9301 acaaccggtc agttgcccca cgggctggaa atcgttgaga tggcgtaacg cgtcatccag
     9361 tttgttgaga tcaaacgtct gagtgaatgg cagcggctgc accggtttac cgatgtcatt
     9421 aagctgctct acgccacaga cgccacagcc cgtgcgcccg gccagtgccc gacggcgctc
     9481 cttcagtccc ataaagcggc ggctggaaag ctcgatttgc acttccaggc cgttacagga
     9541 aggaacgacg tccatgccga agatatcgcg cggactttcg ataatccctt cggaaagcga
     9601 aaaaccaagc gcaaagcgtt caaggtcttt gggcgaggcc atcatcacca cgtgcgaaat
     9661 gccgttgtag accagcgcaa caggaacttc ttccgccact tcatcaagtc gcggatgttg
     9721 taaatcatca cgccgccata cctcaatttg gcgaacgcct gtgacatttg tcacatttat
     9781 gatttctttt tgctgtgttt ttttcacttt tttttaacca gataagaaca cacacaccaa
     9841 cattatggta ttctgttaca aacccttcct ggacggaggg aaattgcgcc aattctggac
     9901 ctttgcggcc ccttccgcaa agaaaaataa ctcccactcc ctgcacacgc agcacgcgaa
     9961 tgtaaatggg acgtgacaat gtcgaaacaa ggagcaatcc atgcaggtca gcagaaggca
    10021 gttctttaag atctgcgctg gcggtatggc aggcaccacg gcagccgcac tgggttttgc
    10081 acccagcgta gcactcgcag aaacaaggca gtataaactg ctgcgtaccc gcgaaacccg
    10141 taatacctgc acctattgtt ctgttggttg tgggctgctg atgtacagcc tcggtgacgg
    10201 agcaaaaaac gccaaagcat ctatcttcca tatcgaaggt gacccggatc acccggtcaa
    10261 ccgcggtgca ctttgtccga aaggcgctgg cctggtggat ttcatccact ccgaaagccg
    10321 tctgaagttc ccggaatacc gtgcccctgg ttctgataaa tggcagcaaa tcagttggga
    10381 agaagcgttt gatcgcatcg ccaaactgat gaaagaagac cgcgatgcta actacattgc
    10441 acaaaacgcc gaaggcgtga cggttaaccg ttggctctcc accggaatgc tgtgtgcttc
    10501 cgcgtcgagt aacgaaaccg gctatttaac gcaaaaattc tcccgcgcgc tgggtatgct
    10561 cgcggtcgac aaccaggcgc gtgtctgaca cggaccaacg gtagcaagtc ttgctccaac
    10621 atttggtcgc ggtgcgatga ccaaccactg ggtcgacatc aagaacgcca acctcgtcgt
    10681 ggtgatgggc ggtaacgccg ctgaagctca cccggtcggg ttccgctggg cgatggaagc
    10741 caaaattcac aacggcgcga agctgattgt gatcgatcct cgctttacgc gtacggcggc
    10801 ggtggctgac tactatgccc ctatccgttc cggtactgac attgctttcc tgtcaggcgt
    10861 attgctgtat ctgctgaaca atgaaaaatt caaccgcgaa tacaccgaag cctataccaa
    10921 cgccagcctg atcgtgcgtg aggattacgg ctttgaagat ggcctgttca ccggctacga
    10981 cgcggaaaaa cgcaagtacg ataagtccac ctggacttac gagctggacg aaaacggctt
    11041 cgccaaacgc gatactaccc tgcaacatcc acgttgcgtg tggaacttgc tgaaacagca
    11101 cgtttcccgt tatacgccag atgtggttga aaacatctgt ggtacgccaa aagacgcgtt
    11161 cctgaaagtc tgcgaataca tcgccgaaac cagtgctcac gataaaaccg cctcgttcct
    11221 ctacgcgctc ggctggacgc aacactccgt tggtgcgcag aacattcgta cgatggcgat
    11281 gatccagcta ctgctcggca atatggggat ggcaggcggc ggcgttaacg ccctgcgcgg
    11341 tcactccaac attcaggggc tgacggacct ggggctgctg tcgcagagcc tgccaggtta
    11401 tatgacactg ccaagcgaga agcagaccga tctgcaaacc tacctcaccg ccaacacgcc
    11461 gaaaccgctg ctggaaggcc aggttaacta ctggggcaac tacccaaaat tcttcgtctc
    11521 catgatgaag gccttctttg gtgataaagc gacggcggaa aatagctggg gctttgactg
    11581 gttgccgaag tgggataaag gctacgacgt cctgcaatac ttcgagatga tgaaagaagg
    11641 caaggtcaat ggctatatct gccagggctt taacccggtc gcctcattcc cgaacaaaaa
    11701 caaagtgatc ggctgtctgt cgaaactgaa gttcctcgtc accatcgacc cgctgaacac
    11761 tgaaacctcc aacttctggc agaaccacgg cgagatgaac gacgtggatc cgacgaagat
    11821 ccagaccgaa gtattccgtc tgccatcgac ctgcttcgcg gaagagaacg gttcaatcgt
    11881 taactccggt cgctggttgc agtggcactg gaaaggtgcg gacgccccgg ggattgcgct
    11941 gactgacggc gagatcctct ccggtatctt cctgcgcttg cgcaagatgt atgccgaaca
    12001 aggtggcgcg aaccccgacc aggtgctgaa catgacctgg aactacgcca tcccgcatga
    12061 gccgaagtct gaggaagtgg cgatggagag caacggtaag gcgctggccg atattaccga
    12121 tccggcaact ggggcggtta tcgtcaagaa aggccaacaa cttagctcgt tcgcccaact
    12181 gcgcgatgac ggtacaacct cctgtggctg ctggattttc gccggtagct ggacgccaga
    12241 aggcaaccag atggcacgcc gtgataacgc cgatccgtct ggcctcggta acacgctggg
    12301 ctgggcatgg gcatggccgc ttaaccgccg cattctgtat aaccgcgcct ccgcagaccc
    12361 gcagggtaac ccgtgggatc cgaagcgtca gttactgaaa tgggatggca ctaagtggac
    12421 cggctgggat atcccggact acagcgcagc gcctccgggc agcggcgtcg ggccgtttat
    12481 catgcagcag gaaggcatgg ggcgtctgtt tgccatcgat aagatggcgg aaggtccgtt
    12541 cccggaacac tacgagccgt ttgaaacgcc gctggggact aacccactgc atccaaacgt
    12601 tatctcgaac ccggctgcac gtatctttaa agacgacgcc gaagcattgg gtaaagccga
    12661 taagttcccg tatgtcggaa ccacctatcg tctgaccgag cacttccact actggaccaa
    12721 acacgcgctg ttgaacgcga ttttgcagcc agagcagttt gtggaaatcg gcgagtcgct
    12781 ggcgaataaa ctgggcattg ctcagggcga taccgtgaaa gtctcctcta accgtggcta
    12841 tatcaaagcc aaagcggtgg tgaccaaacg tattcgcacg ctgaaagcga acggcaaaga
    12901 tatcgatacc atcggtattc cgattcactg gggctatgaa ggtgttgcga aaaaaggctt
    12961 tattgccaac acgttaacac cattcgtcgg tgatgcaaac acgcagacgc cggagtttaa
    13021 gtccttcctt gtgaatgtgg aaaaggtata acggagacga catatggctt atcaatcgca
    13081 agacattatt cgtcgctccg cgactaacgg tctgaccccc gcgcctcagg cgcgggactt
    13141 ccaggaagaa gtagcaaagc tcatcgacgt caccacctgt atcggctgta aagcctgtca
    13201 ggtggcatgt tcagagtgga atgacattcg cgatactgtc ggcaataacg ttggggtata
    13261 cgacaacccc aatgatttaa gcgccaaatc gtggacagta atgcgcttct cggaagtgga
    13321 gcaggacgac aaactggaat ggctgattcg caaagacggc tgtatgcact gtgccgatcc
    13381 tggctgcctg aaagcatgtc cggcggaagg cgctatcatt cagtatgcta acggcattgt
    13441 cgatttccag tccgagcagt gtatcggctg cggttattgc atcgccgggt gtccgttcaa
    13501 cgtgccgcgc ctcaacccgg aagacaaccg ggtttacaaa tgtacgctgt gcgttgaccg
    13561 tgtggtggtt gggcaagaac cggcctgcgt gaagacctgc ccgacggggg cgattcactt
    13621 cggtacgaaa gaatcgatga aaacgctggc gagcgagcgt gtggctgagc tgaaaactcg
    13681 tggttacgac aacgcgggtc tgtacgatcc ggcaggcgtc ggtggtacac acgtcatgta
    13741 cgtgctgcac catgctgaca agccgaatct gtatcatggc ttgccggaaa acccggaaat
    13801 cagtgaaacc gtgaaattct ggaaaggcat ctggaaaccg ctcgcggctg ttggctttgc
    13861 ggctaccttt gcggccagta tcttccacta cgtgggtgtc ggtccgaacc gtgcggatga
    13921 ggaagagaat aatctgcatg aagagaaaga cgaggagcgc aaatgaaacg acgtgacacc
    13981 atcgtgcgct acaccgcgcc ggaacgtatc aaccactgga tcaccgcctt ctgcttcatc
    14041 ctggcggcgg tgagcggaat gggctttttg ttcccctcct tcaactggtt gatgcaaatc
    14101 atgggcacac cgcaactggc gcgaattctg cacccgtttg tcggcgtggt tatgtttgcc
    14161 tcgttcatca tcatgttttt ccgttactgg caccacaacc taatcaatcg ggatgatatc
    14221 ttttgggcga agaatattcg taagatcgtc gtcaacgagg aagtaggtga caccgggcgt
    14281 tataacttcg gtcagaaatg cgttttctgg gcggcgatta ttttcctggt gctgctgctg
    14341 gtgagcggcg tgattatctg gcgtccttat ttcgcgcctg ctttctcaat cccggtgatc
    14401 cgattcgcgt taatgctgca ttcatttgcc gcagtggcgt taattgtggt tatcatggtg
    14461 catatctacg ctgccctttg ggtaaaaggc acgattaccg ccatggtgga aggatgggtt
    14521 accaacgcat gggcgaagaa acatcacccg cgctggtacc gtgaggtccg caagacaacg
    14581 gaaaagaaag ctgaatgagt attcgcataa tcccgcaaga tgagctgggt tcgagcgaga
    14641 aacgtacggc ggatatgatt ccgccgttat tgttccctcg actcaaaaat ttatacaacc
    14701 gccgcgccga acgtctgcgc gaactggccg aaaataatcc gctgggcgat tatctgcgct
    14761 ttgctgcgct tatcgcccac gcccaggaag tggtgctgta cgaccatccg ctggagatgg
    14821 acctgactgc gcgcattaaa gaagccagcg cacaaggcaa gccaccgctg gatattcacg
    14881 ttctgccgcg tgataagcac tggcaaaagc tgctgatggc gctgattgct gagctgaaac
    14941 ctgaaatgag cggcccggcg ctggcagtga ttgagaatct ggagaaggca tcgactcagg
    15001 agctggaaga tatggccagc gcactgtttg cctctgattt ctcgtccgtc agcagcgata
    15061 aagcgccgtt tatctgggct gcgctgtcgc tctactgggc gcaaatggcc aacctgatcc
    15121 ccggtaaagc ccgcgcagaa tacggcgaac agcgtcaata ttgcccggtc tgtggttcta
    15181 tgccggtgtc cagtatggtg caaattggta ccactcaggg gctgcgttac ctgcactgca
    15241 acctgtgtga aaccgaatgg cacgtggtgc gtgtaaaatg cagcaactgc gaacagagcg
    15301 gcaaactgca ctactggtca ctggatgacg aacaagccgc aattaaagcc gaaagctgtg
    15361 atgactgcgg cacttacctg aagatttttt atcaggaaaa agatccaaaa gttgaagctg
    15421 tagcggatga tctcgcgtct ctggtgctgg acgcgcgtat ggaacaagaa ggctacgctc
    15481 gcagttccat caacccgttc ctgtttccgg gggaagggga gtaatctctg atgttttccg
    15541 ggtggcgtag gtcgcccgga ttacggttga tagggtgtga ttacaccatc tctcgtattt
    15601 cgcgttatcc attcaagacc atgccgccag tgcttgtttg gcctcgttct tccctccaac
    15661 acatcaataa ggttattggt atgtcactga tgacaagcgt aagattgcct gatgcgctgc
    15721 gcttatcagg cctaccaata aactacaata tattgagctt tcaaggcttt gtaggctgga
    15781 taaggcgttc acgccgcatc cggcatgtac aacgtgcact ttgccagatg ccagaaacac
    15841 gggatattgc tgtttgcgat tgattttcca tatattgttc tatcgcttct cgtaataggt
    15901 ctgcacatgg aagattgcgc agcaccttga gatcatcaag tcacttaatc acctcatcgg
    15961 ataactcgag taaaattctg cccatatcca tacctgccag aggattcata attatttcac
    16021 caatattatt tttgaattta tgttatcatc tacaacccgg caaccaatga ccaaactata
    16081 tatggaaaga tgatataggt gatattgcac ggtttccgct cccctctctt ccgcttacat
    16141 ttacagctaa ccaacccaca tttaattcca gagagttagt ggataaatta ttttaaaggc
    16201 gtagatattg tttccctgaa tttttacgcg gtgatgaaga tttcaggtta tatagcatga
    16261 tcctctggtg tggaaaaatt atacttcctc aacgatcacg ttatatttaa atatcaatag
    16321 cacacattca tacttattaa tatattcata acttaaatga gtttatactt tgacaacctg
    16381 acctgccatt tgctattttt attacaatat aatttataga gttataatta tgaaaataaa
    16441 taaatttatc tcacataaaa aaatgaggct tttttttgct caagagataa aagcaattag
    16501 ccgctggcca tacggcacag aaggtatcga gttgagccga ctccctggcg atgttcgcta
    16561 taacctcatt ccaccagagg cgccatggca catagacgtt aacgatgact acatggagtt
    16621 caggcgctca cctttttgga tggtatcggg agaagtattt atgggattta ttctttccct
    16681 actgtcaata tctttcctgt tagtgaccgt aagttcattt tttgcattag gttatagtcc
    16741 tcatttattt ttcgcttatg ttatcactgc gtttttttgc attgcagtct tacccagcgc
    16801 ggcaaaaatc gcatttttga ccccacatta tcttcccatc cgatttaaca gaaaaacgca
    16861 aaaaatttat gttgccgacc taaagataga aggtggtata tttttccgca agataaaatt
    16921 aacctttagg gagatggact ggaaggatgt ggaggcctgg tcggtaagtc gacgttttgc
    16981 taaaaactca ccttattttg ggcttcatct tgttgaaaac acctcgaatg agatcagcct
    17041 attaaaacaa acgcgcatgt atgcaacccg agcgccgtgg acaaatgaag aatgggaaag
    17101 acaaagaagt tatattccca aaatctggag ctactgccag cattacatgg cctttatgcc
    17161 tgttcctgat gaatcgacca aaccgaagcc atttgttttt ttgaaaaata attggctatt
    17221 taaatggccg gaagagatgg atgcgcgttc caaaagttca ggggatacgg tttagttatc
    17281 atgctcattc tccagcaatg acacctaaag agaaagttta ccatcctgaa tgacacaaaa
    17341 aagagttaca tatatttaga taaggagata caaacatgat tgaactgata tcagataaac
    17401 aatccgacat attcaatcac aaagatacct aatatttatg atcgtacaat agtatagacc
    17461 agttcacaca ccatatatat aacaaagcaa ataaaagcaa gagaacataa aatttcaatc
    17521 aaaaataaca cagtttcaat taataatgca attattctta taacctcctg tagataaaca
    17581 agaaggcagc caactataaa tgcgggaaca ccaataaagg cgatcctgat aatatagttc
    17641 aagtcaattg acagaatttt attcatcata aaaactgtta caacaaaacc aacaataaac
    17701 aagccaaaag accagatttc ctcatcaggt tttggcggtg aatcttttga taaacggagt
    17761 atcttcatat accaccaatc attcatagaa taaatatatc gaagtttgat gatatagtat
    17821 aaccatcagg ttataagcaa gatgtgaatc taatctcatt atcaatgtgg cgctttcaaa
    17881 cgatagttat ttttattatt cgattatatg agttctgaac gctgacgctt tctgtataca
    17941 ccctaacgca acatgttttt caaatcattg acaatcgctc gcaacagagc ctttgcaggc
    18001 tcggttgtag aattctgata actccaacga atattaatta tcaattactc atcgacccag
    18061 tatatgcgtt tgatttatgg ataaaatcaa catttttaaa aaacgaatct tgtaaaacat
    18121 cggtatttat gttcccttcc aaccctacat tgaatttatt ggcaatatga aggatacgaa
    18181 tatcaaaaag atcttttaac atcactaatt cttcagttgt gagtgattca caactgaaat
    18241 aaccctcttt gtcaaagaga gtttctattg ttgtatgctc agcgaggcgc ttttcaatca
    18301 atgtctgtaa cagagagttg ccaagaacaa cagaagtggt gcgatctttc gcagatttac
    18361 accccatcat aacaacaacg ttcgtatcac cattatgact ttgatttatc gccgtagcta
    18421 aaatattagt caatgaggca aacggaacgg aattcctttc ataattcaat tcccccacca
    18481 tttcattcca tttacggaaa atcgggagat atttttcccg cgcaacatta tccatctggt
    18541 taaacagatc agccatgcgg cttttaacca tctctatttc cggtgaactg gacatgctcc
    18601 gcgcataata tgggcctgat gatgtggcat acattaatgc cgcacccaca cctgtcgcca
    18661 tgatgggggc agccacggtt ttggcaaagg cgacactacg gtggctatgt gcttcacaat
    18721 gtaaaggtat gtattctact ggctgcgata attcttcgca tgcctctctt atcatttcag
    18781 tatgttttac aaataacggt ttttcacttc ccgaaacaac catctgctta attgcactaa
    18841 gaaaacgtaa atcaagaaga accgttttgg gtttattatt tttcggcaga tttttcatta
    18901 tccctcccat aacctgcctg gccgcatatt gatcttgttg tacagcacat aaaataattg
    18961 ttgaaacttt ctctactgca ctattaatgt taatgttaaa ctgcgcctgc catacgttga
    19021 cgggcagatc gagaatgtca gaaccaactt ctccggcggg atatttattc gtaatcgacg
    19081 gacgtgaatc tacgagaaat tttagctgca atctgtgctc aatattaccg gctgttttcg
    19141 tcgtgtgatc aaacataaaa gcattacttc tcatatcatc acacattttc tgaatttttt
    19201 cgcgtctttc ttgtggtgat gtagcttcaa ctttgaactg attattttta cctgtacatt
    19261 ccgcgacaac agagggaacg ttatctaaag tgtcatataa aatcgtaatg tcactgatac
    19321 ttttgtcatg cagataagtt tgattaacac tcgaagtatt tacaaaaagg tcaatatcat
    19381 aattattttt aatttcaccg acatcaagta aataatgctt actctggaga actccctcct
    19441 tatttagttg ggcatcaatc agtatttctc ccgattttgt caccatatcc tttccataaa
    19501 ccatttgcat agccatttcg aggaggtctt tatccaattg accacaatcg ttgagtaatc
    19561 ggctaccaaa taatttatat acggttcccg tcattgccaa agcagcactt tccggcactg
    19621 ttcgtttcca cagtgaacct tctctatttt tgaataaact atattcattg ttactcgaca
    19681 gtccatgttt tagttcattt acacaactgc tcagttgctc ctgagcatcc attttaaggc
    19741 gatgagaaaa atcatttaat agcgtttgct tctgtgactc attgctcgaa cgcaattttt
    19801 ctaaattaat tacagaataa tatttttgtt taataagatt aatatcaaca accattttag
    19861 cctcctgcac atgatttaat cacaaacgta taatagctta taacaattca ggataataaa
    19921 ttgatgatac taacatgatg acaatctatt attttcacta atacaaatta cgaagtcatt
    19981 ttttatgatt ttctgacact ccatataaat atcttaatca gcaaatattt ttatattact
    20041 tgcttgatac cgatttaaat ggctattatg tggaaaatac tccatctgag cgtactccaa
    20101 ctatcaaaaa acgctcaaat ctgaagttat atgataaatt aagcattatc tacgatgatt
    20161 gtgcaatcat aagaatttcc acaaatgata cacatggacg tttttactgt aattaatgtt
    20221 tagataaaac tggaagaaat agtcaaaagc taacaaatac gttagatgta aataacctga
    20281 atggatgaga gaggcttcac cgccccctcc cccctctact cttcttcgtt cccgccctct
    20341 tcatacgggc caaatggctt cgcgggcaga acgatatacg tgccttcaaa cactgcaccc
    20401 ggcgtctcgt cgccaaagat ttctacttgc atctgcaccc gtgcttttcg tccgcgcgcc
    20461 agacggtcga gatcgccact taacgcaccg aggtcggcta ccgcatgcgg tttaccgcta
    20521 atcggcttgc tgtagcggat atgcgcatcg gcaagaataa tcgttccacc gaggtggcgt
    20581 tcgcgcagca tcagccagat aagcccccaa ccggtgagcg ttgccagcga gaataaactc
    20641 ccggcaaaca acgtatgatg cggattctga ttgccggttt ccggcatggt ggtgataaat
    20701 ttttgcccgg tatattgctg aatgcgcaca cccatttttt cactaagcgg gatatgttca
    20761 taccatgcct gctggagctg ggcgcaccag tcgccgcgat gaagaatatc atccagagtg
    20821 gcgacgggtt taatcatcag aaaatggcga atcggcgtgg tggtaggcgt ggtgatttct
    20881 ccctgattga caaaccccag cttggcgaaa aactccaccg cgtcttcacg agcgctacag
    20941 gtcacgcgct taacgccttc ctggcgggct accgactcca gagtcatcgc catcagcgtt
    21001 cctaatcctt tgtcctgcac gtcgggatga acagccataa agcgaatgga cgcttcgtta
    21061 tcggcattaa tatacagccg accgaccgcc accagattac cctgctcgtc gacgaccatc
    21121 tggtgatgcg ccatcgcatc ccaggcgtcg cgttcagaac ctttcggttg atgcaggggc
    21181 ttacgcaaca tctcccaacg gaactgatag tagcgctcta attcttcttc tgtttgtgga
    21241 acccgaaggt gatacatagc gatactctct cttgtttccc gtgacaaccc tggaagctgg
    21301 ctcatacctg caaccagaat gtcacggggc cgtcattgac cagcgatacc tgcatatccg
    21361 cagcaaagcg tcctgtttgc gtgttcatct cttgctgacg acagcgttcg acgaaatagt
    21421 catataacgc ctctgcgcga tctggcggag cccctttgga gaagctgggg cgcatccccc
    21481 gttcggtatc tgcggcaagg gtaaactggg aaaccaccag cacactgccg cccgcctgtt
    21541 gtacgttgag attcatcttg ccttcggcat cgctgaaaat acgatagccg agcacgcgct
    21601 cgcacagacg gtttgctttc tgttcgtcat catccttttc gacacccaat aacaccaaaa
    21661 gtcccgcgcc gatttcgccc gtcacttctc cctccacggt gacgctggca cgggttacgc
    21721 gttgaattaa tgcaatcatg gttcgtcgtc ttcttcttgt tcagcagctt gctttagttt
    21781 gcggtattcc ccgagagtga cagtaatttc cgcgccaagc aagacgatac accatgtcca
    21841 gtagacccag acgaagagaa tggggatcac cgccagcacg ccgtaaataa gctgatatga
    21901 cgggaacatg gtgatatata gcgcgaaacc tttctttcct gcttcgaaca ggagtgcggc
    21961 gacaaacgca ccgacaatcg cgtcgcggtt ggggacgcgg atggtaggaa caatgctgta
    22021 cagcagccag aaggagatcc acgacaacag cagcggaaaa atacgcagca cattgtcgat
    22081 aacggtattg agatcgctcg cccagcgcag ggaaagcaga taggaactga tcgccagact
    22141 ggcccccgcc agcagcggcc ccagcgtcag gatcatccag tacaccgcaa acgagtaaat
    22201 tttgggtcgc gcccgtttac ttcgccagat ggcattcaac gcactatcga tggagtacat
    22261 caacaataac gccgtgacga tcaggccaca cgccccaaca gcagtcatct tgttggaatt
    22321 ggcgacaaac tgttcgatat atcgctgaat aacatcgcca gtagcaggta gaaagttggc
    22381 gaagataaag tgacgcaact gaatgctgac gtcggaaaac atgggaaaag cggcgaaaag
    22441 cgcaaaaaca acggcaacca gcggcactaa tgagagtaac gacacatagg caagattacc
    22501 tgccagggtt gtcatgttgt cctcatcaat gcgttgccag agtagtttca gccaggccca
    22561 tagcggacgg gtatgatgcc tggctttatc ctgaatgttt tttagcataa cactttcgcg
    22621 aaatagtccg ggatggtggt tttatctttc accagaatgc tggtaatgcc cagttgatta
    22681 gccccttcta tattatcggc gttatcgtca aaaaagaccg tatcgtcagg tgaaaatcct
    22741 tctgcctgta aaacatgctg gtaaattcgc gcttcgggtt tgcgcatacc caattcttgc
    22801 gacagataga tatggtcggc agcatcacgg atttccgggt attcttctgg ccagaaggta
    22861 gtatgcaggc ggttagtatt ggaaagcacc actacgcgat gcccctgctc acgcagttta
    22921 tgcatgatag cgatcacttc cgggcgtagc gcgacaaata ccgcctgcca accgtgggag
    22981 aactgctcat agcttagcgg tagagccatc tcatgacaca gcacctctgc gaacgcttcg
    23041 tcactgatct ccccgcgctc atgctgatga aatgcctcgc ccatatgaaa actcttctta
    23101 agcgtagcca gcggtatacg cgttaaatcg ctccacgttc ccagcacacg gttgaagtcg
    23161 atatcgacaa tcacattacc taaatcaaag atatagagca tttttgcctc ctttctcgcc
    23221 acaagaaatt aactgtagcg ggaaaggatg agtttggcta tgaggtcagg cgcgaagcca
    23281 ggttaacggt cacaaaaatc tatgcatcgt cctggggaag gataatttcg atttggctgt
    23341 cctgtaagcg cgattttaag gcggcaggcg gttcctcgtc ggtaaaaagc gcggtgacct
    23401 gcgccacatt accaatctct accgctgcgg aagcgtgata cttcgtatga tcggcgacca
    23461 acagaatatt tctggcgtgc gccatcatcg ttttcaccac gttggcttca ttcacatcga
    23521 actccatcaa cgcgccatca ctctcaatcg cacccacgct tgccaccaga taatccgcgc
    23581 gaaaatcagc aacaaacgac gctgcagaag ggccaatgat cccgctatta tgcgaacgca
    23641 atatgccgcc aggcaccatc acttcaaagc gcgggttatg ataaagaata tgcgccacac
    23701 gcaggctgtt agtaataatc cgcagatggt tatggttaag taacgctcgg gctacgtgct
    23761 ccaccgtggt gccgatagtg ataaaaattg tcgaaccatc aggaatatag tcggccaccg
    23821 cttcggcaat ggcttttttt tcctctgtct gcgaaacctc acgctgttcg aatgccatgt
    23881 tgacgacgct ggaggcccga cccgcaccac catgatggcg cgtaatcagt ccttgttcgc
    23941 tcaatttacg aatatcccgg cggaccgtct gcgtggaaac atccaacaga ttcgccagct
    24001 catcgatatt catataccca cgctccgcaa tcagcatgag aagttggtcg tgccgcgggt
    24061 taccggtcaa ttcggtaaga ctcatgggaa ttcctcgaaa aaccatcacc ctggcatttt
    24121 atacaaaaag tgacaaaaaa gatcgggttt gatcacagtc agggatccca gctctgccac
    24181 caggacgcgt acatttcagc gctgcaacgc cgctggcaaa ccggactgac tccgctaacg
    24241 tcccgccagt cgccagcgcc accgctaatg cgccgtgaaa aacatcgccc gcgccggtgg
    24301 tatccaccac atcaactttg aaagccggtt gatgctgtcg cccgccattt tccagccagt
    24361 cgcaaccggc actcccctga gtaacataga catgtccatt tgtgagcatt tgcgcttgtt
    24421 ttagcgcact cgccatctcg ttcacgcccg ttaagcgcac cagtcccggt tctgagaaag
    24481 ccgcgtgatc gcttaacgcc accagctcgc tgatatcctg cggcgtaata tcaccatcca
    24541 gtacagttat cacgcctgcc tgccgcgcca gggtgaacgc ttttttcgcc ccgtcatg
//
