LOCUS       NC_014500.1            21845 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014500.1 Dickeya dadantii 3937, complete sequence.
ACCESSION   NC_014500
VERSION     NC_014500.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:40:41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 778584
            Orig. end    :: 800429
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1527)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_2"
                     /gene_functions="transport (smcogs) SMCOG1005:MFS sugar
                     transport protein (Score: 173; E-value: 2.6e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_699"
                     /sec_met_domain="MFS_2 (E-value: 1.8e-51, bitscore: 173.0,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKPITLKHTLCYGSANLLGSGALAISGAWLMYFYTTFCGLSLVE
                     AAAIFSVASVIDAISNPIMGYISDNFYNTRIGRLFGRRRFFILLGIPLVLVYPMLWMEG
                     LGFWYYLSTYVLFELIYTSIMVPYETLATEMTTDFKVRSKLTGSKAIFGKVANFLAAFI
                     PGQFIGIYGKDSATPFFYTGLAYGFIMCAAMIALYLTSWERSPSEVAREHTQNLWQSLK
                     KLSIDMASTFRLRIFRKHLGMYLFGFGAEWLFASAFTYFIVFGLKQSTAVVSQLNSFSS
                     IMQFISTFLFIGICVKMGFGRPYRMALMVVIVSVIAYAALYFTGWSQTATIIVLFGITA
                     IFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSVIVFAMGWIL
                     SQFGFVSGKAAQPESAVLAIVGVFSLGVVALAVVAIYYSTQMRLDRKNHMILLQEIARI
                     KAGGAIADVPPEARAVAEELTGWKYEQCWGNNPLGLQQDVQEPVVATSQR"
     protocluster    1..21845
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[787664:791198](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9081..12614)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..21845
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21845
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="PFOR_II_pathway"
                     /region_number="2"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1954..2190
                     /locus_tag="ctg1_700"
                     /transl_table=11
                     /translation="MSELLVRRAMPIVIRLDVLLAQKKMKSRELAGLIGITEQNLSLLK
                     SGKVKSIRFDTLQRICEVLCCQPGDVLEYLSEE"
     CDS             complement(2369..3865)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_701"
                     /sec_met_domain="Mannitol_dh (E-value: 3.3e-43, bitscore:
                     145.4, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Mannitol_dh_C (E-value: 4.6e-97, bitscore:
                     322.3, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSNTLSGNEKNLSNTELPAAVQQPRYDRQSLKPRIVHIGFGAFH
                     RAHQALLTDRVLNRQGGDWGICEVVLFSDDTLISALRRQDHRFTVLEKAAHGNQAIVVG
                     AVCKSLHARVEGIAAILEQLADPIVAIVSLTITEKGYCRAGSKGELDRDNPLVQQDLAH
                     PRQPSSVPGLLAEALRLRRERGIAPFSVLSCDNVPENGKVTRQVVMDAARLQDPALADW
                     IAQHVTFPNTMVDRIVPAATPETLSQIADAVGVADPCGIACEPFIQWVVEDKFVAGRPD
                     WELAGAQLVDDVLPFEEMKLRMLNGSHSFLAYLGYLAGYEHINNCMDDPSYRRAVRHLM
                     LQEQAPTLHVSGVDLTAYADQLLERFSNPALKHRTWQIAMDGSQKLPQRLLASLRWHLA
                     RGSDHRALTLGVAGWMRYVGGTDDAGQAIDIRDPLAATLQQVVSTTRDDAERVRGLLSI
                     SALFGDDLPGNAAWVAALTDAYLSLRDNGAKATVAALFND"
     CDS             complement(3967..5571)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 157.8; E-value: 1.1e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_702"
                     /sec_met_domain="MFS_1 (E-value: 7.8e-47, bitscore: 157.8,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPIEAQAARFGHHYRWLATVTIMLGTIATTATATIVNVAMRDIM
                     GAFGMGQDQAQWLSTAFLASMTATMLITAWTLERFGYRATYVGSLAVFIAGSLLGTFSQ
                     SSAEVILARILQGGASGVIQPLAMIIISQVFPVSERGKAMGIYGVGVVLAPALGPAAGG
                     LMVDQLDWRAVFMVVVPFCLAGIAAALVILPAKSAQTDSTPRRFDTLGFILLVTALTSL
                     LAGLSNGQREGWESFFILCLLTTAVIATLAFIIREFTTPYPLLSLRVFANPAFTSGCIV
                     AFALGAGIYGSTYIIPLFVQSIQGYTPTRSGLLLMPAGLALGMVFPLAGSLSDKLKPHQ
                     LVIAGLLLFGLSCWLSSAADTDTPFWTMAWWIVIGRVGLGVMLPAMNAGALRALPHAQL
                     AQGAGSLNFVRQLGGAMGVNLLSVFIERRATFHGQMLAQSLTLDNIRSTDAIRQLSLLF
                     GHGGNPLGDPLNTSINPGIMTYLESVLAPKAQMFAYQDGFFMVAMFFFLAILPAWFIRP
                     RPVLNPTSPPGAAKTPA"
     CDS             complement(5558..6694)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_703"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 3.3e-07,
                     bitscore: 28.0, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIHASKLAGFRRMSQRQRTFLLAGAALLLLAVLVLAYWFHQRFT
                     HIDETDARVMGEVISLASRESGWVTARPVIDGDAIHKDQLLAQIDDRDARLRLAEQEGN
                     LAAADAQISYSQTQRQVTDLTTQASLDEARAKLASSDSAVNNAGYQLSLAQNNFQRDDQ
                     LLKSNLTARKTWDESHTTLLQRQSELREAEAQRHAQQAALNNAVAQRNTLQVLDRQIEM
                     QRQQRIALQAQVDQLKQEIADRALRSPVDGVVDRTIVNVGSYVQAGQWIMLVHDPRNLW
                     VEANIKETAIGRVRVGQKVDIQVDAYPDKHFSGHVIRVGDAATNQFALLPSPNPSGNFT
                     KITQRVPVRIALDDPENDSPDNRLKPGLMAEVSINVAD"
     CDS             complement(6691..7146)
                     /locus_tag="ctg1_704"
                     /transl_table=11
                     /translation="MSQTESSARRRFALQLGQTSRLWRRVIDRELQPYGLTQATWLPLL
                     FIAREDTPIHQKALAESLGLDASAVVRVLDSLQKQGFIERREGNDRRFREIHLTALGLE
                     QVEKVESIAGQVRNQALAGVSEQDIEQVSRVIHQVISNLSRTENGHS"
     CDS             complement(7464..8567)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_705"
                     /sec_met_domain="LysM (E-value: 0.0046, bitscore: 15.0,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMSIRAILTLVVAAAAFSQTALAVVYPLPAPNSRLVGENIQVTI
                     PSDSTDALEHFAAQYQMGLSNLLEANPGIDVYLPKPGSTMTVPQQLILPDAPREGIVIN
                     SAEMRLYYYPKGSKTVVVLPIGIGQLGKDTPINWVTSVQRKKERPTWTPTAAMHAEYAA
                     RGEFLPQVYPAGPDNPMGLYALYIGNLYAIHGTNANFGIGLRVSHGCVRLRDKDIKYLF
                     DHVPVGTRVQFINEPVKATVEPDGSRYVEVHNPLSRTEEEFNSDTPVPLKLTPAVTKVL
                     ADASVSESTVNQALQNRIGMPTKVNGPAENVAPIEPAVPAAPQAPVIQQTNTPATPDNA
                     QPAAPQAQPTITDAAPAAATATDASKS"
     CDS             complement(9081..12614)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_706"
                     /sec_met_domain="PFOR_II (E-value: 1.7e-13, bitscore: 48.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.1e-80, bitscore: 267.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.5e-33, bitscore: 114.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-08, bitscore:
                     32.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.1e-10, bitscore: 38.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.3e-05, bitscore: 22.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.3e-07, bitscore: 28.6,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.033, bitscore: 12.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.2e-23, bitscore: 78.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITTDGNNAVASVAWRTNEVIAIYPITPSSTMAEQAAAWSSDERK
                     NIWGDTPRVVEMQSEAGAIATVHGALQTGALSTTFTSSQGLLLMIPTLYKLAGQLTPFV
                     LHVAARTVATHALSIFCDHSDVMAVRQTGCAMLCASNVQEAQDFALISQMASLNSRLPF
                     IHFFDGFRTSHEINKIEPLSDAQLHALLPQAAIDAHRERALTPERPVIRGTASNPDTFF
                     QAREATNPWYNAAFGHVEQAMDDFARETGRQYQPFEYYGHPDATRVIVMMGSGVGTCEE
                     VIDTLLTRGEKVGVVKVRLYRPFSAQHLLAAIPPGTQSIAVLDRTKEPGAQAEPLYLDV
                     MTALAEAFSRGERPLMPKVIGGRYGLSSKEFTPQCVEATYKELALTNPRARFTVGIYDD
                     ITHLSLPLSDQPMPTQASLEALFYGLGSDGTVSAAKNSIKIVGNSTPLFVQGYFVYDSK
                     KAGSLTVSHMRAGPHPIHSAYLIEQADFVACHQWQFIDKYSMVERLKPGGIFLINTPYS
                     ADDLWHRLPQEVQAGLNQRQARVFCINAAKIARECQLGARINTVMQMAFFHLTQILPGD
                     DARDKLRAAIASSYGSKGQELVERNWRALDATLAALEAVALEPVNPDSPCRPPVVSDAA
                     PDFVKTVTAAMLAGLGDSLPVSALPPDGTWPVSTTQWEKRNIAEEIPLWKPDLCTQCNH
                     CVAACPHSAIRAKVVPADAMAGAPESLQSLDVKARDMRGQKYVLQVAPEDCTGCNLCVE
                     VCPAKDRQNPEIKAINMEPRLDHVATEKTHYDFFLKLPEIDRSKLERIDIRTSQLITPL
                     FEYSGACSGCGETPYIKLLTQLYGDRLLVANATGCSSIYGGNLPTTPWTTDANGRGPAW
                     ANSLFEDNAEFGLGFRLSVDQHRQRALRLLEQLKPQLPADLVADLLEDSVAADARREQI
                     ARLRQSLSAIDSADARQLAAEADHLVDKSIWLIGGDGWAYDIGYGGLDHVMSLSENVNV
                     LVLDTQCYSNTGGQQSKATPLGAVTKFGENGKRKARKDLGINVMMYGHVYVAQISLGAQ
                     LNQTVKAIQEAEAWPGPSLIIAYSPCEEHGYDLAFSHDQMRQLTATGFWPLYRFDPRRT
                     AEGKPALVTDSRPPSASLSETLLNEQRFRRLNNQQPEAAALLYEEAEADLRRRYDFLTL
                     MAGKAEKNPQE"
     CDS             13157..13579
                     /locus_tag="ctg1_707"
                     /transl_table=11
                     /translation="MFIDLRDKMVSVLARIRERGYGPEEAINHIVQSLGSRYSDVSKVN
                     VLTSKLIADVIHSTYQDETSPLEIAAIIRMLGYASRDVVGGIHEQFPQLTPEEVGRLVL
                     NEKVYPKTDRASFVAAMTYGGYSREESEQAANSLYS"
     CDS             13729..14274
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_708"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.9e-07,
                     bitscore: 28.3, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQPILTTEHLVLRPLQATDVTDVCALLNSTPDISAMTMLIPYPC
                     PRETVANWVADLQGNWEQRKGVAYAICLSQSQQLIGSISLVSLETDQPEIGYWLGADFR
                     QRGFGTEASRALCQFAFSQLSIEKIYGCHLPQNVASGRVLLKCGFHSLGMRHVFLTARQ
                     QQETVAVYMMPSPMMAMV"
     CDS             complement(14299..14922)
                     /locus_tag="ctg1_709"
                     /transl_table=11
                     /translation="MASDILAIAAIGGVLALGAMSPGQSFILVARTALASSRRTSLAVS
                     LGMGAGAAIFALIALLGLQSLLLAVPWLYQVLKIAGGCYLLYLAFTLFRARPHHTAPTL
                     RDDPAPPPTHAFRLGLLTQLSNPNTALVFGGVFAALLSQHIAGWMYVALPLLAFVIDFL
                     WYALVALLLSSSRPRSAYLRFKTVFDRLSGTVIAALGIRLLLQK"
     CDS             15019..15744
                     /locus_tag="ctg1_710"
                     /transl_table=11
                     /translation="MKLRATLLAGSVLLAGCDLKPAAEPVNPVLAGLSNVFGFDALRGK
                     VKRFTQTQIDDAGKVTAYVEGEFDAEGCLAALRTYQPSMNLDLDLVRNGQMLVEQSDRQ
                     ALFQLTDHCQLANTNDGRLSYRSNDKYAIAEVVYRDKPTPLASYRYDDDGFPVSMTFVS
                     PENGKVTKVEMRNDAPAQKRLDATVVVTENDEQVSVTRTSCQYDQHFNPRLCQVLVSNG
                     KGAAQTVTTLTHTTKIEYY"
     CDS             complement(15874..17442)
                     /locus_tag="ctg1_711"
                     /transl_table=11
                     /translation="VEPSLTTSPWNPDRGDGRYRNPILFADYSDPDIVRVGEDIYLVSS
                     SFNHMPALPILHSRDLVNWTLINHVFTRFDLPGYERFQPGKGVWAPSIRYHAGKFWVFF
                     STPDEGIFMCQADDPRGDWSAPHCVQPAKGWIDPCPFWDDDGSAWLVHAFAFSRSGRKH
                     QLQLCRMSSDGRQLLDEGRIIVDGTAAQPTLEGPKLYKRNGWYYIFAPAGGVPTGWQTV
                     LRAASLQGPWQARVALHQGRSAVNGPHQGGWVELENGESWFVHFQDRHAYGRVVHLQPM
                     RWQDDWPLIGAQSGDGGPGEPVENAAMPAVRADNIRAQPATSDDFTADRLGLQWQWQAN
                     PDAGWYEMCRPGLRLFCQPMPQRHGAPSWYDVPNLLMQKFPAETFTVTTRLQAALENVG
                     DRCGLMVYGERFAFLGLEKTADGVALTSGYGWMTDAQELRQYAGPALPVGEEAHTLELR
                     VTVLPNARCQFAWRTPDGGFTPVGEPFAAGPGKWVGAKIGLYALSLPEQRGPGRVDVDF
                     FHVTP"
     CDS             complement(17465..18922)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_2"
                     /gene_functions="transport (smcogs) SMCOG1005:MFS sugar
                     transport protein (Score: 344.8; E-value: 1.9e-105)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_712"
                     /sec_met_domain="MFS_2 (E-value: 1.3e-103, bitscore: 344.8,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNNNKLSTADNKLSTAEKIGFGMGDAACGIVYSSVTMFLTYFYT
                     DIYGISAAAVGVMFLVTRVLDAVIDPMIGLLADRTRTRWGHFRPWLIWFAVPYAVIAVL
                     TYTTPDLAGTGKLVYAYITYTLLMMFYTFINIPYCSLGGVITTDEKDRLSAQSYRFTIS
                     SAAGLLVSVGTLWLVDWIGRGDKQLGYQGTMAIMGVLAVIMLVFCFFTTQERINPQVDQ
                     GQNVWDDVKNLLSNDQWRIVAVITFFSSMAGVMRGAATLYYATYLMIGPEHSGAAGTAM
                     KSAFITTSVVGTIIGAMLAGYFAKRYRSLSLFKNINLLLVITGVVLFLVPPTWLAVVFP
                     LYFLIGFFHQMYQPFKWNMMANAADYGEWKTGRRITGLSFSGNLFALKLGMAVAGALVG
                     FALGWFGYVAGSPTQTSLATTGIIGLLSIGPSLSYLILYWLTRFYKLDDKTMTQIQADL
                     ARRHATPQPATEQDDGVNPHLTPRGAA"
     CDS             complement(19440..19679)
                     /locus_tag="ctg1_713"
                     /transl_table=11
                     /translation="MYVELVYDKRNVSGLPNAAEQIKNELAKRIHRVFPDAEIKIKPMQ
                     ANAINSNASKQDKSTINRIIEEMFNEADEWLTPE"
     CDS             complement(19749..19859)
                     /locus_tag="ctg1_714"
                     /transl_table=11
                     /translation="MPAHRPLLSIACAARSLLNGDDPLCVYMEKAIAGCS"
     CDS             19994..20389
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyoxalase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_715"
                     /sec_met_domain="Glyoxalase (E-value: 8.9e-07, bitscore:
                     27.1, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLRVARPVTDLQRSERMYRDGLGLQKLGSFAQHDGFSGVMLGR
                     QGLAWHLEFTVCHTHPVMPAPTEDDLLVLYVSDHEGWQASCDRMVQAGFSVVASFNPYW
                     ERQGKTFRDPDGYRVVLQQGRWPNADL"
     CDS             20404..20688
                     /locus_tag="ctg1_716"
                     /transl_table=11
                     /translation="MYIISLTYNAPLDEVENLLERHVTWLKRGYEQGVFVASGRKNPRT
                     GGVILAKSVGREELDDFLKQDPFQAVANYEVIDFQPSMTVDAFAALSRI"
     CDS             complement(20745..21845)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_717"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.3e-79,
                     bitscore: 264.5, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 1.1e-30,
                     bitscore: 104.1, seeds: 635, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIRVGVVFGGKSSEHEVSLQSAKNIVDAIDKTRFDVVLLGIDK
                     QGEWHVNDASNYLLNADNPALIALNRSSQNVALIPGQTHHQLIDTASASALSQIDVIFP
                     IVHGTLGEDGSLQGLLRMANIPFIGSSVLGSAVSMDKDVTKRLLRDAGLQVAPFVTLTR
                     ANRARHPYDSVTAQLGLPLFVKPANQGSSVGVSKVRNQAEFERAVDLAFRYDHKVLVES
                     AIVGREIECAVLGNDYPKASVCGEIVLHDEFYSYDTKYINEDGAAVAIPAAMDDEVHQH
                     IRDIALRAFQTLDCQGMARVDVFLTPDQQVVVNEVNTLPGFTNISMYPKLWEASGLGYT
                     ALITQLIELALERHAQDSNLQSSVRE"
ORIGIN
        1 ttagcgttga gacgttgcaa ccactggttc ctgcacgtcc tgttgcaggc caagcgggtt
       61 gttgccccag cactgttcgt atttccagcc ggtcagttct tcggcaaccg cgcgggcttc
      121 cggtggaaca tcggcaatcg cgccgcctgc tttgatacgc gcaatttcct gcagcagaat
      181 catgtgattc ttacggtcca gacgcatctg ggtgctgtag tagatcgcga cgaccgccag
      241 ggcaaccacc cccagcgaga acacgcctac aatcgccagc accgcgcttt ccggctgagc
      301 cgctttgccg gacacgaatc cgaactggct cagaatccag cccatggcga agacgatgac
      361 ggaacgcacc atcttgccgg cgaaggtcat ggcgccggcg taaatccctt cacggcgacg
      421 gccggtcagc acttcgtcca cgtccgccag gaaggtgtag accgtccagg gaatgtagta
      481 gataccgccg gtgctcagac cgaagatggc ggtgataccg aacaggacga taatggtggc
      541 agtttgagac cagccagtga aatagagcgc tgcgtaggcg atcacgctga caataaccac
      601 catcagcgcc atgcggtacg ggcgaccgaa gcccattttc acgcagatgc cgatgaagag
      661 gaaggtggag ataaactgca taatcgagct gaagctgttg agctgggata ctaccgcggt
      721 gctctgtttc agaccgaata cgatgaaata ggtaaaggcg gaagcgaaca gccattcagc
      781 gccgaaacca aacaggtaca tcccgagatg tttacggaaa atacgcagac ggaaggtcga
      841 agccatgtcg atgctgagtt ttttcagcga ctgccacagg ttctgggtgt gttcgcgcgc
      901 cacttcgctc ggggaacgct cccaggaggt gaggtagagg gcgatcatcg ccgcacacat
      961 gatgaagcca taagccagac cggtgtagaa gaacggcgta gcggagtctt taccgtagat
     1021 gccgatgaac tgtcccggaa tgaaggcggc caggaagttg gcgaccttac cgaagatggc
     1081 cttggaaccg gtcagcttgg aacggacttt gaagtcggtg gtcatctcgg tggcgagcgt
     1141 ttcgtacggc accatgatgg aggtgtaaat cagctcgaac agcacatagg tcgacaggta
     1201 gtaccagaag cctaaccctt ccatccacaa catcgggtag accagcacca gcggaatacc
     1261 gagcaggatg aagaagcgac ggcgaccgaa caggcgcccg atgcgggtat tgtagaagtt
     1321 gtcgctgatg taacccatga tcgggttact gatggcgtcg atgacgctag ccacggagaa
     1381 aatggcagcg gcctcaacca gagacaagcc acagaaggtg gtatagaagt acattaacca
     1441 ggcaccacta atggctaaag cgccactgcc tagcaggttc gcgctgccgt agcagagcgt
     1501 gtgtttcaac gtgatgggtt tactcatgat caattcgcct aacaatatta aaacattatt
     1561 tcatttgaaa tgaacttatg ttcttatcat ttgcctgatc gagacaaaag taaactagcc
     1621 atcccactcc cggcggcttt taataggaat ctgtcaggga gatcatgaaa taagtttttt
     1681 taatttgatc acgaatattg accggaaaaa cgcgatgttt gccggaaggc atcatttttt
     1741 tatcgtaaaa cgataaaaat tattagcggt aggggcgata gcgtcggaag aagtggtgaa
     1801 actatcatcg ctatttcgca gtgccagccg gcaaaaatca agaataattg taaaaaacag
     1861 cgatgaactg tgatcgagtt gtgatcctgt ggagaacaca ccgcgaaaag tgtgatttat
     1921 ctcacggcac cagacagtgt attttatcgg gtcatgagtg aattgttggt aagacgcgct
     1981 atgccaatcg ttatcagact ggacgtgctg ctggcacaaa aaaagatgaa gtcccgcgag
     2041 ctggcggggt tgatcggcat caccgaacag aatctttcgc tgctgaaatc cggcaaggtg
     2101 aaaagcatcc ggttcgatac attgcagaga atatgcgagg tgctgtgctg tcagcctggc
     2161 gatgtgctgg aatatttgtc ggaagagtga aggccggtct actggtgctc agccatgccg
     2221 gtatcaaacc acctgccgac ggcatccatc ggagcacgcc gcgctcaggg tttccttcct
     2281 gagcgcggcg tttttgcatg gcgtcagcgc cgtgtggcat gtgatatgcc acgacacagc
     2341 acgacacgga tcaagcgcat cacgccgatc agtcgttgaa taacgccgca acggttgctt
     2401 tggcgccgtt gtcgcgcaac gagagatagg cgtcggtcaa cgccgccacc cacgccgcgt
     2461 tgccgggcag gtcatcgcca aacagcgcgc tgatggacag cagaccgcgg acccgctcgg
     2521 cgtcgtcacg ggtagtgctg acaacctgct gcaacgtggc ggccagcgga tcgcggatat
     2581 caatcgcctg accggcgtca tcagtgccgc cgacgtaacg catccagccc gccacgccca
     2641 gcgtcagggc gcggtggtcg ctgccgcgcg ccagatgcca gcgcaacgac gccagcaggc
     2701 gctggggcag tttctggctg ccgtccatcg caatctgcca ggtgcggtgt ttcagcgccg
     2761 ggttggaaaa acgttcaagt aactgatcgg cataggcggt caggtctacg ccggacacat
     2821 gcagggtcgg agcctgttcc tgcaacatca agtggcgcac cgctcgccgg tagctggggt
     2881 cgtccataca gttattgata tgttcgtaac ccgccagata gccgaggtaa gccaggaaag
     2941 agtggctgcc gttaagcatg cgcagcttca tctcttcaaa cggcagcacg tcatccacca
     3001 gttgcgcgcc cgccagttcc cagtcggggc ggccggcgac aaacttatct tctaccaccc
     3061 actgaataaa cggctcgcag gcgatgccgc acgggtccgc cacaccaacg gcgtcggcga
     3121 tctggctcag cgtttccggc gtggcggccg gtacgatccg gtccaccatg gtgttgggga
     3181 aggtgacatg ctgcgcgatc cagtccgcca gcgcgggatc ctgcaggcgt gcggcgtcca
     3241 tcaccacctg tcgagtgact ttgccgtttt ccggcacgtt gtcgcaggac agcacggaga
     3301 agggcgcaat gccccgttca cgacgcaggc gcagcgcttc ggccagcaat cccggcaccg
     3361 acgagggctg gcgagggtgg gccagatcct gctgcaccag cgggttgtcc cggtcgagct
     3421 ctcctttgct gcctgcacgg cagtaacctt tttcggtgat agtcagcgag acgatcgcga
     3481 cgatcgggtc cgccagttgt tccagaatcg ccgcgatccc ttccacgcgc gcgtgcagcg
     3541 acttgcagac cgcgccgacc acgatcgcct gattgccgtg ggcggctttc tccagcacgg
     3601 taaaccggtg atcctgacgg cgcagggcgg aaatcagggt atcgtcgctg aacaacacca
     3661 cttcgcaaat cccccagtcg ccgccctgac ggttgagcac ccgatcggtc agcagcgcct
     3721 gatgcgcgcg gtgaaacgcg ccgaagccga tatgcacgat acggggtttc aacgactgac
     3781 gatcgtaacg gggttgttgc acggcggcgg gcagctccgt gttggacaga tttttttcgt
     3841 tgccggacag agtgttactg gacatagatg gcgtcctgaa aagagaaaaa ttaaccgccc
     3901 aaccttagcg gtctttcggt tgggcggcaa ctgtcatatg gcgtgttctg aagccggttc
     3961 gcagaatcat gccggcgtct tcgccgcacc gggcggcgac gttgggttca gcaccgggcg
     4021 cggccggata aaccaggcgg gcaatatcgc cagaaaaaag aacatcgcca ccatgaaaaa
     4081 gccgtcctga taggcgaaca tctgcgcttt gggcgccagc accgactcca gataggtcat
     4141 gatgccgggg ttgatgctgg tattaagcgg gtcgccgagc ggattgccgc cgtgaccgaa
     4201 cagcaggctg agctggcgga tggcgtcggt gctgcggata ttgtccagcg tcagcgactg
     4261 cgccagcatc tggccgtgga aggtggcgcg ccgttcgata aataccgaca gcaggttgac
     4321 ccccatcgcg ccgcccaact gacggacgaa attgaggctg cccgcgccct gcgccagttg
     4381 cgcgtgcggc agcgcccgca gcgcgccggc gttcatggcg ggcagcatca ccccgagccc
     4441 gacgcggccg atgacaatcc accaggccat ggtccagaac ggggtatcgg tgtccgccgc
     4501 gctggacagc cagcaggaca gcccgaacag cagcagaccc gcaatcacca actggtgggg
     4561 tttgagcttg tcgctgagcg accccgccag cggaaatacc atgccgagcg ccagccccgc
     4621 cggcatcaac agcagaccgg agcgggtagg ggtgtatccc tgaatgcttt gcacgaatag
     4681 cgggatgatg taagtcgagc cgtagatacc cgcgcccagc gcgaacgcca cgatacagcc
     4741 ggaggtaaac gccgggttgg cgaacacccg taggctgagc agaggataag gcgtggtgaa
     4801 ttcgcggatg atgaacgcca gcgtggcgat cacggcggtg gtcagcaggc agagaatgaa
     4861 gaacgactcc cagccttcgc gctgcccgtt ggacagcccg gccagcagcg aggtcagcgc
     4921 cgtcaccagc agaataaatc ccagggtgtc gaaacgccgg ggcgtgctgt cggtctgcgc
     4981 acttttagcc ggcaggatca ccagcgcggc ggcgatcccg gccagacaga acggcaccac
     5041 caccatgaag accgcgcgcc agtcgagctg gtcgaccatc agcccgccgg cggctggccc
     5101 caatgcgggc gccagcacca ccccgacgcc gtaaatgccc atcgccttgc cgcgttccga
     5161 taccggaaac acctgcgaga taatgatcat cgccagcggc tggatcacgc cgctggcgcc
     5221 gccctggaga atgcgggcga ggatcacctc ggcgctgctc tggctgaagg tgccgagcag
     5281 gctgccggcg atgaacaccg ccagtgagcc gacataggtg gcgcggtagc caaagcgttc
     5341 cagcgtccag gcggtgatca acatggtggc ggtcatggaa gccagaaagg cggtggacag
     5401 ccattgcgcc tgatcctgac ccatgccgaa ggcgcccata atgtcacgca tcgccacatt
     5461 gacgatggtc gccgtggccg tggtggcgat ggtacccagc atgatggtga ccgtcgccag
     5521 ccagcgatag tggtgaccga agcgggcggc ctgggcttca atcggcgaca ttgatgctga
     5581 cttccgccat caggcccggt ttcagacggt tgtccggact gtcgttttcc ggatcgtcca
     5641 gcgcgatacg caccggcacg cgctgggtga ttttggtgaa gttgccggac gggttcgggc
     5701 tcggcaacag cgcgaactgg ttggtggccg catcgccgac ccggatcaca tggccgctaa
     5761 aatgtttgtc cgggtaggcg tccacctgaa tatctacttt ttggccgacc cgcacccgac
     5821 cgatggcggt ttccttgatg ttggcttcga cccacagatt gcgcggatcg tggaccagca
     5881 tgatccactg tccggcctgc acgtaactgc ccacattcac aatggtgcga tccaccacgc
     5941 catccaccgg agaacgcaac gcccggtcgg cgatttcctg tttgagctga tccacctgcg
     6001 cctgtaatgc gattcgctgc tggcgttgca tctcgatctg tcggtccaac acctgcaacg
     6061 tgttgcgctg tgccacggcg ttgttcaacg ccgcctgctg agcgtggcgt tgtgcttcgg
     6121 cttcccgcaa ttcgctctga cgctgtagca gtgtggtgtg ggactcatcc caggttttac
     6181 gggcggtcag gttgcttttc agcaactgat cgtcgcgctg gaagttattc tgcgccaggc
     6241 tgagttggta gccggcattg ttaacggcgg agtcgctcga cgccagtttc gcccgcgctt
     6301 catccagcga ggcctgggtg gtgagatcgg tgacctgacg ctgcgtctgg ctgtagctga
     6361 tttgagcatc ggcggcggcc agattgcctt cctgctccgc cagccgcaaa cgggcgtcgc
     6421 gatcgtcgat ctgcgccagc aattgatctt tgtggatggc gtcgccgtca ataacggggc
     6481 gggcggtcac ccagccgctt tcccggctgg ccagcgagat cacttcgccc atgacccggg
     6541 cgtcggtttc gtcgatatgc gtaaaacgct gatgaaacca gtatgccagc acgagcaccg
     6601 ccagcaacag caaggcggcg ccggccagca aaaaggtacg ctggcgttgg ctcatacgcc
     6661 ggaaccccgc cagtttagat gcgtggatat tcatgagtga ccgttttcgg tgcgggagag
     6721 attgctgata acctgatgga tgacccggct gacctgttcg atatcctgtt ctgatacccc
     6781 tgccagcgcc tgattacgta cctgcccggc gatggattcc accttctcta cctgctcaag
     6841 cccgagcgcg gtgagatgaa tctcgcgaaa acgacgatcg ttgccttcac gtctttcgat
     6901 aaatccctgt ttttgcagac tatccagtac ccgcactacc gcagaagcgt ccagccccag
     6961 cgattcggcc agcgctttct gatggatggg ggtgtcttcg cgggcgatga acagcaacgg
     7021 tagccaggta gcctgcgtca atccatacgg ttgcaattcc cggtcgataa cccggcgcca
     7081 taagcgggag gtttgaccca actggagggc gaagcgccga cgagcggaag attcggtctg
     7141 tgacatgatg aaatccgtgg gatagatgaa atgttattag ttaacaagtc aactaatgat
     7201 aagtcaattg attttgtgaa gtgaatcata aacagcagtg caacaggctg ctgatgcaaa
     7261 ttacgtctca ccccaggtgt ggatcgacgg tttctcaatg acagtaaggt aatagacagc
     7321 aagttagtgg gcggcaaggc aatggacaca aggcaatgat tgcaggcggg atgaaatagg
     7381 ctgcgtggag gagaaggggc tagcggaaaa caaacagggc agcgtaagct gccctgtgaa
     7441 caggatgata accaggggat cgatcaggat ttgctggcgt cagtcgccgt agcggctgcc
     7501 ggcgcggcgt cggtgatcgt cggctgggcc tgaggcgccg ccggttgtgc attatccggc
     7561 gttgccggcg tgttggtctg ctggatgacc ggcgcctgcg gcgccgcagg tacggctggt
     7621 tcgatcggcg cgacgttttc cgccgggccg ttcactttcg tcggcatacc gatacgattt
     7681 tgcagtgcct gattcaccgt gctttcactg acgctggcgt ccgccagcac cttggtcacc
     7741 gccggggtca acttcagcgg aactggcgtg tcggagttga actcttcctc ggtacgggac
     7801 agcgggttat gaacttcgac ataacgtgaa ccgtccggct ccacggtggc ttttaccggc
     7861 tcgttgatga actgaacgcg ggtaccgacc ggaacgtggt caaacaggta tttgatgtct
     7921 ttgtcgcgca gacgcacgca accgtggctg acgcgcaggc cgatgccgaa gttggcgttg
     7981 gtgccgtgga tggcgtacag gttgccgatg taaagcgcgt acagccccat cgggttgtcc
     8041 gggccggccg ggtagacctg aggcaggaat tcaccgcggg cggcgtattc tgcgtgcatg
     8101 gcggcggtcg gcgtccaggt cggtcgctct ttcttgcgtt gaaccgaagt cacccaattg
     8161 atcggggtgt ctttaccgag ctggccgatg ccgatcggca acaccaccac ggttttggaa
     8221 cctttcgggt agtaatacag acgcatttcg gcactgttga tcacaatgcc ttcgcgcggt
     8281 gcgtcaggga gaatcagttg ctgcggcacg gtcatggtgc tgcccggttt tggcagataa
     8341 acgtcaatgc ccgggttggc ttccagcaga ttactcaggc ccatctggta ctgagcggca
     8401 aagtgttcca gcgcatcggt gctatcgctg ggaatagtga cttggatatt ttcacccacc
     8461 agccggctat tcggggctgg taatggataa accacggcga gtgctgtctg gctgaaagca
     8521 gccgccgcca caactagtgt caggatcgcg cgaatactca ttttcatatc tttgttgagt
     8581 gttaaaagcc attgcggcaa aggaattgtt gttatccggt acaataagtc cggatgcgca
     8641 ttatatgtgc agaagggcgg caggaaaacc agatgtacaa tcaattacat tatatacccg
     8701 tcatacttca agttgcagat gcgttggctt tattactcag cccatccctg ggcctcgccc
     8761 cttcggggcc gcagctagct gcgttcaact ctgctcccgg cagagttgtc actcacccca
     8821 gtcacttact tatgtaagct cctggggatt cgctgcgtcg ccgcgttaca agactcatta
     8881 tgagtcttgc cctgaagggc caacgctttg cattgttcaa aacgcaacgc gttttgtcct
     8941 gcaactcgaa ttattttggg tataagcatc gggcgtgggg aaatcgggcg acaaataaag
     9001 ggaacgaatg gcgtggtcgg cacgtgctgg aaagaatcag ggagcggttt cccgctccct
     9061 gagtgatccg cgtgagcggg ttattcctgg gggtttttct ccgccttgcc cgccatcaga
     9121 gttaggaagt catagcggcg gcgcaggtcc gcctcggctt cttcatacag cagggcagcg
     9181 gcttccggct gctggttatt gagccggcgg aagcgttgct cgttgagcag ggtttcgctc
     9241 aggctggctg acggcggacg ggagtccgtc accagcgccg gtttgccttc cgccgtacga
     9301 cgcgggtcga agcgatacag cggccagaaa ccggtggcgg tcaactggcg catctggtcg
     9361 tggctgaatg ccagatcgta accgtgctct tcgcaagggc tgtaggcgat gatcagcgac
     9421 gggcccggcc aggcttccgc ttcctgaatc gctttcaccg tctggttaag ctgggcgccc
     9481 agcgagatct gcgccacgta gacgtggccg tacatcatca cgttgatgcc gaggtctttg
     9541 cgcgccttgc gtttgccatt ctcgccaaac ttggtgacgg cgccgagcgg ggtggctttg
     9601 gactgctggc cgccggtgtt ggaataacac tgggtgtcga gcaccagcac gttaacgttt
     9661 tccgacaggc tcatcacgtg gtcgaggccg ccgtagccga tgtcgtaggc ccagccgtcg
     9721 ccgccaatca accagatgga tttgtccacc agatgatcgg cttccgccgc caactggcgg
     9781 gcgtcggcgc tatcgatggc gctgagtgac tgacgcaggc gggcaatctg ttcacggcgc
     9841 gcatcggcgg caacagagtc ttccagcagg tcggccacca ggtcggcggg cagttgcggc
     9901 ttgagctgct ccagcagacg aagagcgcgc tggcgatgct ggtcgacgct caggcggaag
     9961 cccagcccga attcggcgtt gtcttcaaac agcgagttgg cccatgccgg cccgcggccg
    10021 ttggcgtcgg tggtccaggg cgtcgtcggc aggttgccgc cgtaaataga ggaacagccg
    10081 gtggcgttgg ccaccagcag gcgatcgccg tacagctggg tcagcagctt gatatacggg
    10141 gtttcaccgc agccggaaca ggcgccggag tactcgaaca gcggcgtgat caactgcgag
    10201 gtgcgaatat cgatacgctc cagtttgctg cggtcgattt ccggcagttt aaggaagaaa
    10261 tcgtaatggg ttttctcggt cgccacatgg tccagacgcg gctccatgtt gatggccttg
    10321 atttccggat tctggcgatc tttggccggg cacacttcca cgcacaggtt acagccggtg
    10381 cagtcttccg gcgcgacctg caacacgtat ttttgaccgc gcatgtcgcg ggctttgaca
    10441 tccagcgact gcagcgattc cggcgcgccg gccatcgcat cggcgggcac caccttggcg
    10501 cggatggcgg agtgcgggca ggcggccacg cagtggttgc actgggtaca cagatccggt
    10561 ttccacagcg gaatctcttc ggcgatgttg cgcttttccc actgggtggt gctgaccggc
    10621 caggtgccgt ccggcggtag cgcggacacc ggcaggctgt cgcccagacc ggccagcatc
    10681 gcggcggtga cggttttgac gaagtcgggc gcggcgtcgg acaccaccgg cgggcggcac
    10741 gggctgtccg ggttcaccgg ctccagcgcc accgcttcca acgcggccag cgtcgcatcc
    10801 agcgcccgcc agttgcgttc caccagttcc tggcctttgc tgccgtagct gctggcgatg
    10861 gcggcgcgca gtttgtcgcg cgcgtcgtcg cccggcagga tttgcgtcag atggaagaac
    10921 gccatctgca tcacggtgtt gatgcgtgcg cccaactggc attcgcgggc gattttcgcc
    10981 gcattgatgc aaaacacccg cgcctgacgc tggttcagcc cggcctgtac ttcctgcggc
    11041 agccggtgcc acaggtcgtc ggcgctgtaa ggcgtgttga taaggaagat gccgcccggt
    11101 ttcaggcgct ccaccatgct gtatttgtcg atgaactgcc actggtgaca ggccacgaaa
    11161 tccgcctgtt caatcaggta ggcggaatga atcgggtgcg ggccggcgcg catgtgggaa
    11221 accgtcaggc tgccggcttt tttggagtcg taaacgaaat agccctgcac gaacagcggg
    11281 gtcgaattac cgacgatttt gatcgagttt ttggcggcgg atacggtgcc gtcgctgccg
    11341 agcccgtaga acagcgcttc cagcgacgcc tgggtcggca tcggctggtc ggacagcggc
    11401 aacgacaggt gggtgatatc gtcataaata ccgacggtaa aacgcgctct ggggttggta
    11461 agcgctaact ctttatacgt cgcttcgacg cactgcgggg tgaattcttt cgacgacagg
    11521 ccgtagcggc cgccgattac cttcggcata agtgggcgct cacctcgtga gaacgcctcc
    11581 gccagcgcgg tcatcacgtc cagatacagc ggttcagcct gcgcgccggg ttctttggtg
    11641 cggtccagca ctgcgatgga ctgcgtgcct ggcggaatcg ccgccagcag atgctgcgcg
    11701 gagaacggcc ggtacagccg aactttcacc acgccgactt tctcgccgcg cgtcagcagg
    11761 gtgtcgatca cctcttcaca ggtgccgacg ccggaaccca tcatcacgat aacgcgggtg
    11821 gcgtccggat gaccgtaata ctcgaacggc tggtactgac ggccggtttc gcgggcgaag
    11881 tcgtccatcg cttgttccac gtggccgaat gccgcgttgt accacgggtt ggtggcttcg
    11941 cgcgcctgga agaaggtatc cgggttggag gcggtgccgc gaatcaccgg acgctcagga
    12001 gtaagcgccc gctcacgatg cgcatcaatc gccgcctgcg gcaacagcgc gtgcaactgc
    12061 gcatcgctca gcggttcgat cttgttgatt tcgtgcgagg tgcgaaagcc gtcgaagaaa
    12121 tgaataaacg gcaaacggct gttgaggctc gccatctggg aaatcagcgc gaagtcctgc
    12181 gcttcctgca cgttgctggc gcacagcatg gcgcaacctg tctggcgcac cgccatcaca
    12241 tccgaatggt cgcagaaaat ggacaacgca tgagtcgcca cggtacgggc ggcgacatgc
    12301 agcacaaacg gcgtcaactg accggccagc ttgtacagcg tcgggatcat cagcagcagg
    12361 ccctgcgagg aagtaaaggt cgtggacagc gcgccggtct gtaatgcgcc gtgcacagtg
    12421 gcgatggcgc cggcttcgga ttgcatctca accacccgag gcgtatctcc ccagatattc
    12481 ttgcgttcgt cgctcgacca ggcggccgct tgttcggcca tggtggagct gggggtgatg
    12541 gggtagatag cgataacttc attggttcgc caggcgaccg aagcgaccgc gttattaccg
    12601 tcggtggtga tcatgactta accttctttg ttgctgaacg atgactctgc tgcgtggcgg
    12661 ctattatcgc tgcccggcga gtttttttga ccgattatag cccgctgagt tgtttcaagg
    12721 tgtgtatggc agcgccactg gccggcaata atagcagttt agggggcact gtgcagttcc
    12781 caaccgggta cgttgcggca gatcctctgc gccggcgttc acattcctgc gcgggaatag
    12841 gacgctggtg ataaacagcg gtgttaatgt atcgttaata aaatcaggtt atatcaccta
    12901 ttatcgtaca gccagacaag agcgtggcgc tgtccgatta aaatccggca ttcgcccgca
    12961 aagcgggaaa tgccagtgga aggataggca tctgcgccta tgctgaaata aagcgccgga
    13021 cacctcctga tgcgggcgtg agcgtcaggc cggcagaaaa atcccagacg cgaccattaa
    13081 ggaaatctgt tcatacttca gggatagtct tcgcgctctt cgggttgatt atcgactttg
    13141 acgaaggaac agcactatgt ttatcgatct gagagacaaa atggtatcgg tattagccag
    13201 aatccgtgaa agaggctatg gaccggaaga agccatcaat catattgttc aatctctggg
    13261 tagtcgttat agcgatgtgt ccaaagtaaa cgtgctgacc tcgaaactga tagccgatgt
    13321 gattcactct acctaccagg atgaaacctc gccgctggag attgcggcca ttatccgcat
    13381 gcttggctac gccagtcggg atgtggtggg cggcattcac gaacagtttc cgcaactgac
    13441 gccggaagag gttggtcgac tagtgctgaa tgaaaaggtt taccccaaaa ctgaccgcgc
    13501 ctcttttgtc gccgccatga cctacggggg ctattcccgc gaggagagcg agcaggcggc
    13561 gaacagcctg tattcctgat ggtcgctgac agacgatatc agggcggcag gctatctttg
    13621 ctgtaggccg gcgctattgc cgccggctgg aaccattctc cgccatgatg ccactgaaca
    13681 gagcgcccgt ggatatgacg acgggatgcg actgatgagg agaatctgat gcggcaacct
    13741 atcctgacta ccgagcatct ggtgttgcga ccgttgcagg cgacggacgt cactgatgtc
    13801 tgcgctctgc taaatagcac ccccgatatt tccgccatga ccatgttgat tccctatcct
    13861 tgcccgcgtg agacggtagc caactgggtt gccgatttac agggcaattg ggagcagcgc
    13921 aaaggcgtgg cctacgccat ctgtttatcg cagagtcagc agctgattgg ttcgatttcg
    13981 ctggtgtcgc tggaaaccga ccagccggaa atcggttact ggctgggtgc cgacttccgg
    14041 caacgaggat tcggcaccga agccagccgt gcgttatgcc agttcgcctt tagccaactg
    14101 agtattgaga aaatctacgg ctgccatttg ccgcagaacg tggcgtccgg ccgggtattg
    14161 ctcaaatgcg gttttcattc actggggatg cgccatgtgt ttctgactgc ccgccagcag
    14221 caggaaaccg ttgccgtcta catgatgcca tcgcctatga tggcgatggt ataagcggcg
    14281 tcgtctggtt tttgtgtctt acttttgcag cagtagcctg atacccagtg cggctatcac
    14341 ggtgccgctg aggcgatcaa acacggtctt gaaccgcaga taggcgctgc gcggcctgct
    14401 tgatgacagc agcagcgcca ccagcgcgta ccacagaaaa tcgatgacga acgccagtaa
    14461 cggcagcgcc acgtacatcc aacccgcaat gtgttgactg agcaacgcgg cgaatacccc
    14521 gccaaacacc agtgccgtat tggggttgct gagttgcgtt aacagcccca gccgaaaggc
    14581 gtgggttgga ggtggcgcgg ggtcgtctcg cagtgtcggc gcggtgtggt gcggtctggc
    14641 gcggaacagg gtgaacgcca gatataacag gtagcacccg ccggcgattt tcagcacctg
    14701 ataaagccag ggtaccgcca gcaacagcga ttgcaggccc agcagcgcta tcagcgcgaa
    14761 gatggccgca ccggcgccca tccccagtga aacggcaaga ctagtgcgtc gcgatgaggc
    14821 cagcgcggta cgtgcgacca gaatgaaact ttgccccgga ctcatggcgc cgagcgccag
    14881 taccccgccg atagcggcaa tagccagtat gtcgcttgcc attttttgct tcccaagagt
    14941 gatggagagt tatctttatc ctctcttttg gaattggcgt aaactgacgc gattcaacgg
    15001 gtatccagga taaggactat gaaactacgc gccacgctgc tggcgggctc ggtattactg
    15061 gccgggtgtg acctgaaacc ggccgcggag ccggtgaacc cggtactggc cgggctttcc
    15121 aatgtttttg gcttcgacgc gctgcgggga aaggtcaaac gctttacgca aacccagatc
    15181 gacgacgccg gcaaggtgac ggcctatgtc gaaggcgagt ttgatgccga agggtgcctc
    15241 gccgcgctgc gcacttatca gccgtcgatg aatctcgatc tggatctggt gcgtaacggg
    15301 cagatgctgg tggagcaaag cgatcgccag gcgctgtttc aactgacgga tcactgccaa
    15361 ctggcgaata ccaacgatgg ccgcctgagc taccgttcga acgacaaata cgccatcgcc
    15421 gaggtggtct accgcgataa gccgacgccg ctggcgagct atcgctacga tgacgacggc
    15481 ttcccggtca gcatgacatt tgtttcgccg gaaaacggca aagtgaccaa ggttgagatg
    15541 cgtaacgatg ctccggcgca aaaacggctg gatgccaccg tcgtcgtgac ggaaaacgat
    15601 gaacaggtca gcgtgacccg caccagctgc cagtatgacc agcatttcaa tccgcgtttg
    15661 tgtcaggtgc tagtctcgaa cggcaaaggc gccgcgcaga cggtcaccac cctgacgcat
    15721 accaccaaaa tcgagtatta ctaggcggtg cttttttctt gtccgcgggg cgttatttag
    15781 cggctgtcgc tattaggcgt gaccgctggc agcggtccaa tgcgggtgat agcctgatgg
    15841 ttgcggcccg gatgcgggcc gcgtaatcgg cgttcagggc gtaacgtgga aaaaatcgac
    15901 gtcgacgcgg cccggcccac gctgttccgg taacgacagc gcatacagcc cgattttggc
    15961 ccccacccat tttcccggcc cggcggcgaa aggctccccg accggggtga aaccgccgtc
    16021 aggcgtgcgc cacgcgaact ggcagcgtgc gttcggcagc accgtcaccc gcagttcaag
    16081 cgtgtgcgct tcttctccaa ccggtaatgc cggcccggcg tactggcgca gttcctgcgc
    16141 atcggtcatc cagccatagc cgcttgtcag cgccacgccg tccgccgttt tttccagccc
    16201 cagaaaagcg aagcgctcgc cgtaaaccat tagcccgcag cgatcgccga cgttttccag
    16261 cgccgcctgc agccgggtgg tgaccgtgaa ggtttccgcc ggaaatttct gcatcagcag
    16321 gttgggaacg tcataccatg acggtgcgcc atgacgctgc ggcatcggct ggcaaaacag
    16381 tcgcaacccc ggccggcaca tttcgtacca gcctgcgtcg ggattcgcct gccattgcca
    16441 ctgtaggccg agccggtcgg cggtgaaatc gtcggaggtc gccggttggg cgcggatgtt
    16501 gtctgcgcgg acggcgggca tagccgcgtt ctctaccggc tcgcccgggc cgccgtcgcc
    16561 cgattgcgcg ccgatcaacg gccagtcatc ctgccagcgc atcggttgca ggtgtaccac
    16621 gcggccgtag gcgtgacgat cctgaaaatg cacgaaccag ctttcgccgt tttccagctc
    16681 cacccagccg ccctgatgag ggccgttaac ggcggatcgc ccctgatgca gcgccacgcg
    16741 cgcctgccac ggcccctgta gcgaagcggc gcgcagcacc gtctgccagc cggtgggcac
    16801 gccgccggcc ggagcaaaaa tgtagtacca gccgttgcgt ttgtagagct ttgggccttc
    16861 cagcgtcggc tgagcggcgg tgccgtcgac gataatccga ccttcatcca gcagttgacg
    16921 gccgtcgctg ctcatccggc acagttgtag ctggtgcttg cgcccgctac ggctgaaggc
    16981 aaaggcgtga accagccagg cgctgccgtc gtcgtcccag aatggacagg gatcgatcca
    17041 gcctttggct ggctgcacgc aatgcggcgc gctccagtct ccgcgcggat cgtcggcctg
    17101 acacatgaag atcccttcgt ccggcgtgct gaaaaacacc cagaatttcc cggcatggta
    17161 gcggatgctg ggcgcccaga cgccttttcc cggctgaaac cgctcgtagc ccggcaggtc
    17221 gaaacgcgta aacacatggt tgatcagcgt ccagttcacc agatcccgcg aatgcaggat
    17281 cggcagcgcc ggcatatggt taaaactgga cgacaccaga taaatatcct cgcccacccg
    17341 cacgatgtcg gggtcggaat agtcggcgaa caatatgggg ttacggtagc ggccgtcgcc
    17401 tcgatccggg ttccaggggg atgttgttag tgaaggttcc acgttgatct tctctccttc
    17461 gctgtcaggc cgcaccacgc ggggtcaaat ggggattgac gccgtcgtcc tgctctgtcg
    17521 ccggctgcgg tgtggcgtga cggcgtgcga ggtcggcctg aatctgtgtc atggtcttgt
    17581 catccagttt atagaaacgg gtcagccagt acagaatcag gtaggacagc gacgggccaa
    17641 tactcagcag gccgataatg ccggtggtgg caagcgacgt ctgggtgggc gaccccgcca
    17701 catagccgaa ccagccaaga gcgaacccga ccagcgcccc ggcgaccgcc attcccagct
    17761 tgagggcgaa cagattgccg gagaaagaca gcccggtgat gcgacggccg gttttccatt
    17821 cgccgtagtc ggcggcgtta gccatcatgt tccacttaaa cggttgatac atctggtgga
    17881 agaaaccgat caggaaatag agcggaaaca ccacggcaag ccaggtgggc ggcaccagaa
    17941 acagcaccac gccggtaatg accagcagca ggttgatgtt tttgaacagg ctgaggctgc
    18001 gatagcgttt ggcgaaataa ccggccagca tggcgccgat aatggtgccg accacgctgg
    18061 tggtgataaa cgcgcttttc atcgcggtgc cggcggcgcc actgtgttcc ggaccgatca
    18121 tcaggtaggt ggcgtagtac agcgtggccg cgccgcgcat cacgcccgcc atgctggaga
    18181 aaaaggtaat gacggcgacg atgcgccact ggtcgttact cagcagattt ttcacatcgt
    18241 cccagacgtt ctgcccttga tccacctgcg gattgatccg ctcctgggtg gtgaaaaagc
    18301 agaaaaccag catgatgacg gccagaacgc ccattatcgc catggtgccc tgataaccga
    18361 gttgcttatc gccgcggccg atccagtcca ccagccacag ggttcccacc gacaccagca
    18421 gcccggcggc ggaggagatg gtgaagcggt aagactgggc ggaaagccgg tctttttcat
    18481 cggtggtgat gaccccgccc agcgaacagt agggaatgtt gatgaaggtg tagaacatca
    18541 tcaatagggt gtaggtgatg taggcgtaaa ccagtttccc ggtgccggcc aggtccggcg
    18601 tggtgtaggt cagaacagca atgacggcgt acgggaccgc gaaccagata agccaggggc
    18661 gaaaatgtcc ccagcgggtg cgggttcggt cggccagcag gccgatcata gggtcgatga
    18721 cggcgtccag tacgcgggtt accagaaaca ttacgcccac cgccgccgcg gaaatgccgt
    18781 aaatatcggt ataaaaatag gtcaggaaca tggtcaccga ggaatagacg atgccgcagg
    18841 ccgcgtctcc catgccgaaa ccgatttttt ccgccgtgct cagcttatta tccgccgtgc
    18901 tcaacttgtt attgttagtc attggaaact ccgatgatgg atatcccgtc atactccgcg
    18961 ttgcagtcgt gtcggtttga ttacccggtc cataaaagga gcattgccct taagggtcaa
    19021 cgcaacgcga atattgtggg tataaaagca acgtttgctc cgttcccgct tattgttgtg
    19081 gttagttgaa tgggagacta ttgcggaatt tcttatgttg gttacgttta ctggtatctg
    19141 ttataccgct cacgaatttg tggggaagga aagagaaagt gacagtaata ataggttttt
    19201 ttcttttaaa tacagcctat taacctgtca gtcaggtgtc caggtggtat aacaatattt
    19261 tggccttcgg cctatcttgt gccctttggc ctgtgctgtg gccgccggca gcctgcgaac
    19321 cggccgggaa cgggatgccg gtcaggcgta cccggcaacg atctggttag cggctcatga
    19381 tggcgtttgc agcggcgaag cggtgcctcg atagacccgg gaaagcggcc tgaccgtcat
    19441 tattccggcg tcagccattc gtcggcttcg ttaaacatct cttcgataat ccggttaatg
    19501 gtggatttgt cctgtttgct ggcgttggaa ttgatggcgt tggcttgcat cggttttatc
    19561 ttgatttccg cgtccggaaa gacccgatga atgcgtttgg cgagttcgtt tttaatttgc
    19621 tccgccgcgt tgggtaaccc gctcacgttt cttttatcgt aaaccaactc tacgtacatt
    19681 agctgcatct ccatgaaaaa tactggctaa atatacagat ttattgcggg gggccgcaat
    19741 cggttttttt aggagcagcc cgcgatcgct ttttccatat aaacgcagag cgggtcgtca
    19801 ccgttaagga gagaacgggc cgcgcaggcg atagacaata gcgggcgatg tgctggcatc
    19861 acaggctcct tattaaccaa taatcggttc gctatttcat ctaatgccat gataaaaagg
    19921 ggaataagcg gtgtggtcgg agtcggccga ccgtggtatg aacccctttt cagccatcag
    19981 aaaggagtga cgtatgacca cattacgcgt ggcgcggccg gtaacggatc tgcaacgaag
    20041 cgagcggatg taccgtgatg ggctagggtt gcagaaatta ggctcgtttg cgcaacacga
    20101 cggcttcagt ggtgttatgc tgggtcggca ggggctggcc tggcaccttg agtttaccgt
    20161 ttgtcatact catccggtca tgccagcgcc gacggaagac gatttactgg tgctgtacgt
    20221 ttccgaccat gaagggtggc aggcgtcctg cgatcgcatg gtgcaggccg gattcagcgt
    20281 ggtggcgtca tttaatcctt actgggagcg gcagggcaaa actttccgtg atcccgacgg
    20341 ttaccgggtg gtgttgcagc aagggcgctg gccgaatgcc gacttataac gaagagaata
    20401 accatgtata tcataagttt gacatacaac gcgccgctgg atgaagtaga aaacttgctg
    20461 gaaaggcacg tgacctggct gaaacgggga tatgaacaag gtgtgtttgt ggcgtccggg
    20521 cgcaaaaatc cgcgtaccgg gggagtgatt ctggctaaga gcgtcggacg ggaagagctg
    20581 gatgattttt taaagcagga tccgtttcag gcggtggcca actacgaggt gatcgatttc
    20641 cagccgtcga tgaccgttga tgccttcgcg gccctcagcc gcatctgagc aacacgctcc
    20701 ggtatgcgcc gcgcgcgcgc cggagcgcat ccatcactgg cgcgtcattc gcgcaccgag
    20761 ctttgcagat tgctgtcctg cgcgtggcgc tccagcgcca gttcaatcaa ctgagtgatc
    20821 agagcggtat agccaagccc gctggcctcc cacagtttcg ggtacatgct gatgttggtg
    20881 aaaccgggca gggtgttgac ctcgttgacg acaacctgct ggtccggcgt caggaacacg
    20941 tctacccgcg ccatgccctg gcagtccagc gtctggaacg cccgcagggc gatatcgcgg
    21001 atatgctggt gcacctcgtc gtccatcgcc gccggaatcg ctaccgccgc gccgtcttcg
    21061 ttgatgtatt tggtatcgta ggagtagaac tcgtcgtgca gcacgatttc gccgcagacg
    21121 ctggctttcg ggtagtcgtt gcccagcacc gcgcattcga tttcacgacc gacgatcgcc
    21181 gactccacca gcactttgtg gtcgtaacgg aacgccagat ccaccgcccg ctcgaattcc
    21241 gcctgattac gtactttgct cacgccgacg gaagatccct gattggccgg tttgacgaac
    21301 agcggcaggc ccagttgggc ggtgacgctg tcataaggat ggcgggcgcg gttggcgcgg
    21361 gtcagggtga cgaacggcgc tacctgcagg ccggcgtcgc gcagcaaccg cttggtgacg
    21421 tctttgtcca tgctgacggc ggaacccagc acgctgctgc cgataaacgg aatgttcgcc
    21481 atgcgcagca acccctgcaa cgagccgtct tcgcccaacg tgccgtgaac gatcgggaaa
    21541 atgacgtcaa tctgcgacag cgcgctggcg ctggcggtgt cgatcaactg atggtgggtt
    21601 tgccccggaa tcagcgctac attctgactg gagcggttta aggcgatcag cgccgggttg
    21661 tcggcgttga gcaggtagtt ggaggcgtcg ttgacgtgcc attccccttg cttgtcgatg
    21721 cccagcaaca ccacatcgaa ccgcgtttta tcaatggcgt ccacaatgtt ttttgcggac
    21781 tgcagtgaca cttcgtgctc agaggattta ccaccaaaaa ccacgccaac ccgaatttta
    21841 ctcat
//
