LOCUS       c00005_NZ_CABK..       23991 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKWO010000005.1 Clostridium mediterraneense isolate
            MGYG-HGUT-01553, whole genome shotgun sequence.
ACCESSION   c00005_NZ_CABK..
VERSION     c00005_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:28:21
            Original ID  :: NZ_CABKWO010000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1589843
            Orig. end    :: 1613834
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23991
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1599843:1603834]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13991
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..23991
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..23991
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="4"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(539..3136)
                     /locus_tag="ctg5_1425"
                     /transl_table=11
                     /translation="MNAEKMTIKVQESLNEAYNTAVRYNHQQVDVIHLFSALVNQEDGL
                     IPNIIEKIGVNIGIIKNDTHIALEKMPKILGEAAKSSGVVASRRINEVLIKAEELSKEF
                     GDSYISVEHLMLSIMDIDKDGAVGKILSKNNIDKKNFLEVLQAVRGNQRVNTNNPEGTY
                     DSLAKYAVNLIDLAKKNKLDPIIGRDDEIRRTVRILSRRTKNNPILVGEPGVGKTAIVE
                     GLAERIVRGDVPEGLKDKVIFSLDMGALIAGAKYRGEFEERLKAVLKEVQEAEGKIILF
                     IDEIHTIVGAGKTEGSMDAGNLIKPLLARGELHCIGATTFDEYRMYIEKDKALERRFQP
                     VKVGEPSVEETISILRGLKEKFEIHHGIRIHDSAIVAAAKLSDRYIKDRYMPDKAIDLI
                     DEAGAMIRSEIDSLPTELDTIRRKLFMLETEKEALSKEEDEASMKRLDALEEELANLKE
                     KNDTLTAKYEKEKEHITEVRELKTELENVKAEIEKAEREYDLNKVAELKYGRVPELSRL
                     IKEKEANMDDQNGEALLKEEITENEISEIISKWTGIPVAKLVEGEKEKLLRLEHELRER
                     VIGQDEATTAVANAVIRARAGLKDENKPIGSFIFLGPTGVGKTELAKTLARNLFDSEDN
                     IIRIDMSEYMEKQAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVVLFDEIEKAHPDVF
                     NIFLQILDDGRLTDNKGKTVDFKNTIIIMTSNIGSSYLLENKSDEIEEEIKDSVMNEMK
                     LRFKPEFLNRVDDIIMFKPLNNEGIKKIVDIFVKSTANRLAERGIKLELTEAAKELLAR
                     EGYDPVYGARPLKRYIGNVLETKLAKEIISGKLANNDTAVIDVEDDQIIIRVK"
     protocluster    842..23991
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1600684:1603834]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10842..13991
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             3349..4881
                     /locus_tag="ctg5_1426"
                     /transl_table=11
                     /translation="LQLTVFDFTKESINLLKTLKQDLNKASDRLDDFFFSLLENNCDGF
                     FNISTRVKSTLSLKEKIIRNNYYLSYNTPEELFINLSDLIGVRIECRFIEDEEDIFKYL
                     KSAFSHINKDGYSYCPQEPNILLDLREEQPLSQKNGFLLYRIDAYIQTENHKFNFELQI
                     KSMVNLFWSEIEHKVIYKNYNMILGDKFYKNILNSIKSNLSMIDNQLLTIYNHMNEFNT
                     SNQAIKKERLEDLLSKMIFDLYTSKVKQDLGISVDFRNACDIIVDYIFCKNNCNTAHDH
                     YNTFIKTSVRLNELFNNDISFRNSILMNRPVHFNSDFSYTIGNKLLQSMNKDFHWNLFF
                     KILFDIEPGDHSEDFEIFVRYLETILSNRESYLNFYLKFNKEQVDILKNDFISSLCNSF
                     LSVDSIEFIYRDKLLEIYEVLDEHCKFICDEIPSFEHYQLYKEIYTEYLYLKLLSIFNC
                     SISIPYAYDFTENLKNSKSKLRITSKGVNYIYSLDKEKAVISTKFLKYIYPR"
     CDS             complement(5006..5596)
                     /locus_tag="ctg5_1427"
                     /transl_table=11
                     /translation="MAKMMGPRFKMCRRLGLNVTGHPKAMERALKGTSRADKKLSDYGT
                     QLLEKQRLRAYYGVMEKQFRRYVEEAFHSRIQPGDMLLRILESRLDNMVYRMGFANSIR
                     QARQMVNHGHFLVNGSKVDIPSYRLQPGDEVVLREKSRKTEMFADNFANNLNTVPYVEK
                     NVEEFKGVYVRFAQREELPITINEQLIVEFYSK"
     CDS             complement(5810..7294)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_I"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_III"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_1428"
                     /sec_met_domain="PGM_PMM_I (E-value: 1.2e-30, bitscore:
                     103.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_III (E-value: 4.7e-17, bitscore:
                     59.3, seeds: 437, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_II (E-value: 3.3e-23, bitscore:
                     79.4, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLKELQSGTDIRGIAMENKEFELTLTEEVVSRIAIGFALFLKE
                     KKLGEKITIAIGKDSRLSGDLLKSAAINTLIDTGVDVIDCNMATTPAMFMSTIMDGYKV
                     DGAIMITASHLPFYYNGMKFFTKDGGVEKEELNKIIDFTTNEELSNTQKGKIIVKDLVS
                     DYSKIIVNNIRVKTGSETPLKNLKILVDAGNGAGGFFVNKVLEVLGADTSGSQFLNPDG
                     NFPNHIPNPEDKQAILSISNAVVKNNADLGVIFDTDVDRAAIVDKDGRAINKNTLIALI
                     SAILLEENPGTTVVTDSITSEGLKKFIEGLGGKHHRFKRGYKNVINEAKRLNSLGEEVD
                     IAIETSGHAALKENYFLDDGAYLVAKILIKLAILKRKGKELNSIISNFRESSEQLEFRL
                     NIDAKNFKGYGENILSEIKLKIKNDKELNIAEPNYEGVKAYINNSKSWFLIRISLHEPI
                     LAINIESEYLNGSKEIIDKIRYLLKDFKNINLGNLN"
     CDS             complement(7403..7783)
                     /locus_tag="ctg5_1429"
                     /transl_table=11
                     /translation="MNKIKQAIFRKSFKIVVLKDLSGECVIKFDIPFKLKEEHREYYYL
                     IDEIPDMINGINKIDLNEEDLIVNISYDNKKINLEYILKILDEAKEFIIEEWDYIKENN
                     EDNLEQLINELKIKFRNRISKY"
     CDS             complement(7909..8844)
                     /locus_tag="ctg5_1430"
                     /transl_table=11
                     /translation="MTIVLAIVIIIIILLLAWSIKIVNTGYVVVLERFGQYHKILEPGW
                     HFIVPFIDHIRRRISVKQQILDIDPQTVITKDNVNIQIDNVIFYKVINAQEAVYNIENY
                     RSGIAYSTTTNMRNIVGNMTLDEVLSGRDKINMELLRIVDQVTDAYGVKILTVEIKNII
                     PPKEIQEAMEKQMKAERDKRAIILQAEGTKQSDIAKAEGEKTAKILSAEAEKEANIRRA
                     EGLKESQLLEAEGKAKAIEEIAKAEAAAIEIVNKAILESGTDERVIALKQVEALKEMAK
                     GPSNKLILPNETLSSLGSIAAIAEMLKNKE"
     CDS             complement(8856..9275)
                     /locus_tag="ctg5_1431"
                     /transl_table=11
                     /translation="VLSVLSSFMIADILFLGISIAALFSIILEFLKFSVEVQIIIFGLI
                     TTLVIVIFYIKYKKNSNENKAEFKNLEQKYIGIRFILENDVSGENLIAFKGSYWTFKNI
                     AKELKVGDEVEVVGIEGNKLLIDKSNNKTEILTKE"
     CDS             complement(9542..9874)
                     /locus_tag="ctg5_1432"
                     /transl_table=11
                     /translation="MPVYKDFNNNLKRVEMTRRRKIILITSIIIVVLLIIALISEHRRE
                     EVYRETYYPPYQQEQQYHQESFGESVAKSAVKGAVSGYVFGKVYNHVRANNAAKHNYNS
                     YHYRKR"
     CDS             complement(10001..10849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1433"
                     /sec_met_domain="Arginase (E-value: 4.3e-75, bitscore:
                     249.8, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRNIPTFMSCDNEYDESEIVIYGAPFDSTTSNRPGTRFASQAMR
                     PDSYGLETYSPYQDKDLEDYKFFDAGDLELPFGNSAKALEIIEEFADKIVADGKKPCMI
                     GGEHLVTLGNIRSLSKKYDDLHIIQFDAHADLRDDYMGEKLSHASVIRRAWDILGDGRI
                     YQFGIRSGERDEIYWGKSHVYTRHFDLETLGEIVEKLKGKSVYVTIDLDVLDPSIFPGT
                     GTPEPGGITFKEIIEGIKILKDANIVGFDINELSPHYDHSGASTAAACKVLREMLLVAS
                     K"
     CDS             complement(10842..11699)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1434"
                     /sec_met_domain="Spermine_synth (E-value: 2.3e-58,
                     bitscore: 193.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.6e-17,
                     bitscore: 60.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYTEEHTKDARFSIKVKEQLYSGKSEFQEIDVFRSEEFGTFF
                     TLDGLMMVTEKDEFIYHDMIVHVPMATNPNIKNVLVIGAGDGGTVRELTRYPGIENIDM
                     VEIDKLVVDVCREYLPQTASKLDDERVNLYYEDGLKFVRGVENKYDLIIVDSTDPFGPG
                     EGLFTKEFYGNCFKALNEEGILVNQHESPYYAEYAKSMKRAHKRIRESFPICRVYQAHI
                     PTYPSGHWLFGFASKKYDPINSDKIDEWNKLGLETKYYNTEIHRGAFALPNYVKNLLEE
                     ARNE"
     CDS             complement(11715..13166)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1435"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2.8e-10, bitscore:
                     37.7, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 6.5e-137,
                     bitscore: 453.4, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFKNEQERAPIYEALKEYKKNKIVPFDVPGHKQGRGNPELREFLG
                     EDCLAVDVNSMKPLDNLCHPTSVIKEAEEIAAKAFSAKHAFFMVNGTTSAVQAMIMSVC
                     KEGDKIILPRNVHRSAINALILTGAIPIYINPGIHNRLGISLGMDIKDIEKAIKEHPDA
                     KAIFVNNPTYYGICSDLKSIVKLAKKHNMYVLADEAHGTHFYFGKDLPMSAMEAGADMS
                     AVSVHKTGGSLTQSSMLLLNTDRLSVDYVRTIINITQTTSGSYLLMSSLDIARRNLALH
                     GEEIINSIVEKANYARNEINKIKDYYAFSDEIINGRDIYDFDTTKLVVNTLDIGLAGIE
                     VYDILRDEYGIQIELGDVGNILAIISVGDTNYNIERLVAALYEIGRMYKKDKKDLIDHE
                     YISPILKVTPKKAFYSEREDVLIEESEGRISGEFIMCYPPGIPILSPGELITREAIDFI
                     LYSKNKGSLLTGLEDMNTEKIKVLK"
     CDS             complement(13179..13991)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1436"
                     /sec_met_domain="AdoMet_dc (E-value: 4.3e-29, bitscore:
                     98.0, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSEKIRLYGFNNLTKTLSFNIYDVCYAKTEKEKQDYIKYIDEQYN
                     SERLTKILCEVTNIIGASVLNISKQDYEPQGASVTLLISEEEIEDDLVDSSCNKGILDY
                     ANGKQRETVVAHLDKSHVTVHTYPEFHPDEDITTFRVDIDVSTCGQISPLNALNYLIGS
                     FDSDVITIDYRVRGFTRDISGRKHFIDHDITSIQNFIEKDTLKRYDTTDINVYQSNIYH
                     TKMMLKEINLDNYLFRVNSYELSPSTRLEIRERLSKEMIEIYSGTNLY"
     CDS             complement(14158..14535)
                     /locus_tag="ctg5_1437"
                     /transl_table=11
                     /translation="VSKITHCEVIIKDDFNNVLIIQKKVKKTEPKLWSIVGKSMRAKES
                     PEQCANRILEKELNVVGFDITKFKEYSLDEENDKVVFSTVLKERMSCHSSISNWKWISL
                     RELENYEFSSNHKEILKDFWN"
     CDS             complement(14698..15111)
                     /locus_tag="ctg5_1438"
                     /transl_table=11
                     /translation="MRHYNLEKKVSKMDRDLEALAIAKKYLSNKDEINEVMDYLNQDRQ
                     VYADELYYEDAKSYIKCCELIRPLLDKELDEKEQQELLENIKEIYGRRAANVTKKTFGL
                     NAWLKHMDIECEWIVKENNNWSTLIIREFGLHE"
     CDS             15341..16879
                     /locus_tag="ctg5_1439"
                     /transl_table=11
                     /translation="MDISNRKLKKALNLYENGEYEAALKICEKYLEKEYSDEEALYLEG
                     AILYRLGRIDDAIVTWKINAEYNKNADAIKHLASIDKEKKEQALSYNNIRDLHSEEREE
                     KEQALQEENNEVISETFETERERFPKSEVTDEPISQEFIEESPELTEIVPSTEVTELTE
                     NTIHDDYVEDIVEESNDSKEYHVVDTNVDELINSSNTVETNHPKTIDLEEFKKRIKHLE
                     SNTSSEENNEEEDDDTPLRAQDFKPQGRNTNNSDIKASKSKRIAATSAIIALILIAGVS
                     YVAIKSNNSPKVAKNDTTKAEDTPKPITKPEEKPADTTAQKPADQTTAPAAMLTPEQAQ
                     NLITDLKYLISVNSIDKVNAILQNTPKDTVPANAMPEYTAAENFMNTTGVNYYYDNAME
                     NYNNGNYLEAIEYFKKAQPYTTEKFRGPTVAYLIAKSYEKLGDINTSLDYYKKYLKEYP
                     TSESYTPEVLYHLALYYNSQKDTVEAKKYANMLNSTFSSSMYNNDNISKIINEQ"
     CDS             complement(16924..18177)
                     /locus_tag="ctg5_1440"
                     /transl_table=11
                     /translation="MESNFEQKISNKRRSKLWMLLAALGPGLLVMLADTDVGSVVTAAQ
                     SGAQWGYKLIGLQLILIPIVYFVQELTNRLGIVTGKGHGELIKEVFGRKWEIFSVLTLL
                     IAVIGALVTEFTGILGVGVLFGIFKWISVPAAALILILITTTGNYKKVEKTAIFIGLFE
                     LLFIIVAFMSKPDLSEIANGFVNQPLMNGDYWLLISANVGAVIMPWMIFYQQSAIVEKK
                     VRKEEIKMSRIDTAIGSVVTQIIVIAVILIVAATIGKTNPNAPLNSVEQIVNALTPFVG
                     SLAGKVLFAAGIVGAGLVAAIVVSLAISWSIGELLNVPASLNNTIKEAPVFYAVYIITI
                     VLSAAIVLSGMPLVSLTIGVEVLNSLLLPIVLGFLIALAWKTLPKEFALKKWEKVILII
                     IYISTCSLGIVTVIDLFI"
     CDS             complement(18501..19769)
                     /locus_tag="ctg5_1441"
                     /transl_table=11
                     /translation="MEINIDRNDSRNEINYKRKNKILTLLSILGPGVLVMLADTDVGSI
                     VTAAQSAAQWGYRLIGLQLILIPIVYFVQELTNRLGIVTGKGHGELIKEAFGKKWEVFS
                     VVTLLVAVIGALVTEFTGILGVGILFGVSKWVTVPLAAIVLILITTTGNYKKVEKTAIL
                     IGLFELVFIIIAIISKPNLNDIAMGFVNQPLKDGGYWLLISANVGAVVMPWMIFYQQSA
                     VVEKKLPKSYLKMSKVDTAIGSVVTQIIVIAIMLIVASTIGKTNPNAPLNSVQQLVDAL
                     TPFVGSFAGKLLFAVGIIGAALVAAIVVSLAISWSIGELLNVPASLNNTIKEAPVFYGV
                     YIITIVVSAAIVLSGIPLVPLTIAVETLNSLLLPIVLGFLIALAWKTLPKEYSLKTWEK
                     VVLIIIYVSICSLGIVTVIDLFI"
     CDS             complement(20168..20935)
                     /locus_tag="ctg5_1442"
                     /transl_table=11
                     /translation="MKLKIEGLEYEIGKQKILKGIDLEIPKGKFVGIIGPNGSGKSTLL
                     KNIYRVYKPNKGKIYIDGKEINEMKSKEIAKELAILAQESSTQFDFTVEDVVKMGRYPY
                     KSMFEDYSKEDIKLVDGMIKRVGLEKYKDRNFNTLSGGEKQRAFIARALVQDTDFIILD
                     EPTNHLDITYQIQLMDIIKDLNVTVFAALHDMNISAMYCDYIIVMKQGEILKSGTVDEI
                     FTSETIKEVFGVDSYISENPVNGRKQIFYISGR"
     CDS             complement(20935..21978)
                     /locus_tag="ctg5_1443"
                     /transl_table=11
                     /translation="MKKSKTSYGLAIIILAAILIVSMIFAISIGSTHIKFNIVYEAVLN
                     KIVGINIFDVSWNNVIETIIFDIRMPRVILAAVTGAGLAICGILMQCVTRNSIADPYIL
                     GISSGASAGAVFVIVIGGAIFGVTLGAFLGSVLCGALVFIIGTKWGRVSSTTRLVLSGL
                     AISTIFSAITNFIIYSAENSNQARAAMFWIMGSLGGAKWSNIILPIVILILVLIISLFL
                     SNSLDLLLFGDTSAIVLGMNVKLIKSIIILLATFLTSVLVSVVGAIGFVGLVVPHISRG
                     LVGSSHKKILILSSLLGAIFLVVSDIIARVIFAPRELPIGIITAIIGGPFFLWLIAKNN
                     YSFGGNE"
     CDS             complement(21978..23006)
                     /locus_tag="ctg5_1444"
                     /transl_table=11
                     /translation="MNKKIKVIIAGIVVAAAVVGFGIFRYNVAVKNKNEVKIADQSSTY
                     KEVKYVYNDGINKPVDVTIKSAPKRAVTLSQFMTETLLSLGLGDRMVGTALLDNPILPE
                     YKEAYDKIPQLKVTEGHQISKESFLALKPDFVSGWLQSLSAKGVGTPEELEQEGIAPYV
                     ESALQGNATIEDVYKDYDQLGKIFNVEDRAQKVVADMKAQIKEVEDRNKTVPEDKKPSV
                     LVYDSGDKDAYVVGGGFANNLITLAGGKNIFGDLNNQWNTVSFESIAAKNPDIIIVTRY
                     LSEPQSVDEKINLLKTNPAFKNVNAVKNNKIFTIDLADLSPGIRAPKAIKEMNTMFYGD
                     VK"
ORIGIN
        1 ataacggctc cccctataga gaatatcatt attattcctg ctattatagc ataaactgat
       61 ttagtctttt taaataaaaa ggctatagat gtagcagata gaaatataaa ataatttaat
      121 aaaaataatg aaaaacttcc taaaataaat gttatagttt ttattattga agccctttgt
      181 aataattcta taattatagt aaatattaat gttaaactaa gccagtatat tataggctta
      241 agtattttct tttgcttaga ttgttgattt cgagatagat taaattttga tttctttatt
      301 ctcattttaa ataaaatctt cccccattct attttttact gttatatcat ttaatcatta
      361 tatcattaat ttacaaataa taattataat catataaatt gttaatataa atataataaa
      421 taataaaaat aaatcacatt tttatcattt ttttatcaaa ttaatcatat ctattatttc
      481 catttttcaa aataaaaaga ttgcttcatt ttattttgaa gcaatccttt atcttaattt
      541 atttaactct tataattatt tgatcatctt ctacatcaat aacagctgta tcattattag
      601 ctagttttcc tgagataatt tcttttgcaa gctttgtttc taaaacatta cctatatatc
      661 tctttaatgg tcttgcccca taaactgggt catatccttc tcttgctaat aattccttcg
      721 cagcttctgt taattctaat tttattcctc tttcagctaa tctatttgct gtagacttaa
      781 caaatatatc aactatcttc tttatacctt cattatttag aggtttgaac attataatat
      841 catcaactct atttaagaat tcaggtttaa atcttaactt catttcattc ataacagaat
      901 ctttgatttc ttcttctatt tcatctgatt tattttcaag taaataagag cttcctatat
      961 tagatgtcat tataattata gtattcttaa agtctactgt ttttccctta ttatcagtaa
     1021 gtctaccatc atctaatatt tgaaggaata tattaaacac atctggatgt gccttttcta
     1081 tttcatcaaa taagacaact gaataagggg ctcttctaac agcttctgtt aattgtccac
     1141 cctcttcata tccaacatat cctggaggtg gtccaacaag tcttgatacc gcttgttttt
     1201 ccatatattc tgacatatct attcttatta tattatcttc actatcaaat aagtttctag
     1261 ctaaagtttt agcaagttct gttttaccta caccagttgg tccaaggaat ataaatgaac
     1321 ctattggttt attttcatcc ttaagtcccg ctcttgctct tataacagca ttagcaactg
     1381 ctgttgtagc ttcatcttga ccaataactc tttctcttag ttcatgttct aatcttagaa
     1441 gtttttcttt ttcaccttcc actaacttag ctactggtat tccggtccat tttgaaataa
     1501 tttctgaaat ttcattttct gtaatttctt ctttaagtaa agcttcacca ttttgatcat
     1561 ccatatttgc ttctttttct tttataagtc ttgaaagctc aggaactctt ccatatttaa
     1621 gttcagcaac tttatttaaa tcatactctc tttcagcctt ttctatttca gctttaacat
     1681 tttcaagttc tgtctttaat tctcttactt ctgttatatg ctctttttct ttttcatatt
     1741 ttgctgttaa agtatcattt ttttctttta aattagcaag ctcctcttct aaagcatcta
     1801 atctcttcat tgatgcttca tcttcttctt ttgataaagc ctctttttca gtttctaaca
     1861 taaataattt tcttctaata gtatctaatt ctgttggaag tgagtcaatt tcacttctta
     1921 tcatagctcc agcttcatca ataagatcta tagctttatc tggcatatat ctatctttta
     1981 tatatctatc agaaagtttt gcagcagcta ctattgctga atcatgaatt cttataccat
     2041 gatgaatttc aaatttttct tttaatcctc ttaatataga aatagtttct tcaacactag
     2101 gttctcctac tttaactggt tggaatcttc tttctaaagc cttatctttt tctatataca
     2161 ttctatattc atcaaatgtt gtagctccta tacaatgaag ctctcctcta gcaagtaaag
     2221 gcttaattaa gttaccagca tccattgaac cctctgtttt acctgctcca actattgtat
     2281 gaatttcatc tataaataat ataatttttc cttctgcttc ttgtacttct tttaaaacag
     2341 cctttaatct ttcttcaaat tcccctctat attttgctcc agcaataaga gctcccatat
     2401 ctaaagagaa aataacttta tcttttaatc cttctggaac atctccccta actattcttt
     2461 cagcaagtcc ttcaacaata gcagttttac ctactccagg ttctccaact aaaattggat
     2521 tattttttgt tcttcttgaa agtattctaa cagttcttct gatttcatca tctcttccta
     2581 ttataggatc taacttattt ttcttagcta aatcaattag gttaactgca tactttgcaa
     2641 gtgagtcata agttccttct ggattatttg tattaactct ttgattacct cttacagctt
     2701 gtaatacttc aagaaaattc tttttatcta tattattttt acttaatatc tttcctactg
     2761 ctccatcttt atcaatatcc atgattgata acataagatg ttctacacta atataagaat
     2821 caccaaattc tttagataat tcttctgcct ttattaaaac ttcattaatt cttctacttg
     2881 caacaactcc acttgattta gctgcttctc caagtatctt aggcattttt tctaaagcta
     2941 tatgtgtgtc attctttatt attccaatat taacacctat tttttcaata atattaggta
     3001 ttaaaccatc ctcttgattt acaagagctg agaataaatg aataacatca acctgttgat
     3061 gattgtatct aacagcagta ttataagctt catttaaact ttcttgaact ttaatagtca
     3121 ttttttctgc attcattatt acttcacctc ttctattatt atattgctct aataatacta
     3181 ctatttttcc ccttcgtcaa aaaaaaattt tattctattc ataattttca tctgtaataa
     3241 caaaaaatat tacaaattac accacattct atacataata ttgttattaa tagtataact
     3301 tgttattata ttaatataat tatttttttc tatagggatg tgtttacttt gcaattaaca
     3361 gtatttgatt ttaccaaaga aagtattaat ttattaaaga cactaaaaca agatttaaat
     3421 aaagcatcag atagattaga tgattttttc ttttctttac ttgagaataa ttgtgatgga
     3481 ttttttaata tctcaacaag agtaaagtct actcttagct taaaagaaaa aattattaga
     3541 aacaactact acctatctta taatacccct gaagaacttt ttataaacct atcagattta
     3601 ataggagtaa gaatagaatg tagatttata gaagatgaag aggatatttt taaatacctc
     3661 aaatcagctt tttcacatat aaataaagat ggctatagtt attgtccaca agaaccaaat
     3721 attttattag atttaagaga agaacaacct ttaagtcaaa agaatgggtt tttgttatat
     3781 agaatagatg catatattca aacagaaaac cataaattta actttgaact tcaaataaaa
     3841 tcaatggtta atctattttg gagtgaaata gaacataagg ttatatacaa aaactataat
     3901 atgatccttg gagataaatt ttataaaaat atactaaatt ctataaagag taatctatca
     3961 atgatagata atcaactctt aactatttat aatcacatga atgaatttaa tacaagtaat
     4021 caagctataa aaaaagaaag gcttgaagat ttactatcta aaatgatttt tgatttatat
     4081 acttcaaaag taaagcaaga tcttggtata tctgttgatt ttagaaatgc ttgtgatatt
     4141 atagttgatt atatattctg taaaaataat tgtaatacag ctcatgatca ttataatacc
     4201 tttataaaaa cttctgtaag actaaatgaa ttatttaata atgatatatc ttttagaaat
     4261 tcaattttaa tgaatagacc agtacatttt aactcagatt tttcttatac aattggaaat
     4321 aaacttttac aatctatgaa taaagatttc cactggaact tattctttaa gatattattt
     4381 gatatagaac ctggagatca ttcagaagat tttgaaattt ttgttagata tttagaaact
     4441 atactttcta atagagaaag ttatcttaat ttttatttaa aattcaataa ggaacaagta
     4501 gatatattaa aaaatgattt tatatcctca ttatgtaatt ctttcttaag tgtagattct
     4561 attgaattta tttataggga caagcttctt gaaatatatg aagttttaga tgaacattgt
     4621 aaatttattt gtgatgagat accatcattt gagcattatc aactctataa agaaatttat
     4681 accgaatatt tatatttaaa attactttca atatttaatt gctcaataag tattccttat
     4741 gcatatgatt ttacagaaaa tctaaaaaat tctaaaagta aattaagaat aactagtaaa
     4801 ggggtaaact atatctattc actagataaa gaaaaagctg ttataagtac aaaattctta
     4861 aaatatatat atccaagata aaaataaatt ttattttata tagaagaaga ccttagcggg
     4921 gcaacgctaa ggtctgttga gtatattaac ataactacat gagatgtaat cttggcaatg
     4981 tatgggtatg aactatttaa tgctattatt ttgagtagaa ctcaacgatt aattgttcat
     5041 taattgttat tggtaattct tctctttgag caaatcttac ataaacaccc ttgaattctt
     5101 ctacgttctt ttcaacgtat ggaactgtgt ttaagttgtt agcgaagttg tctgcaaaca
     5161 tttctgtttt tcttgatttt tctcttaaaa caacttcatc tcctggttgt aatctgtatg
     5221 aaggtatatc tacctttgat ccatttacta agaaatgtcc atgattaacc atttgtcttg
     5281 cttgtcttat tgagtttgcg aatcccattc tgtaaaccat gttatctaat cttgattcta
     5341 agattcttaa taacatgtca cctggttgaa ttctactgtg gaaagcttct tcaacgtatc
     5401 ttctgaattg cttttccata accccatagt aagctcttaa tctttgcttt tctaataatt
     5461 gagtaccata gtctgataat ttcttatcag ctctgcttgt tccttttaaa gctcgttcca
     5521 ttgcttttgg atgaccagta acgttaagtc ctagtcttct acacattttg aaacgaggtc
     5581 ccatcatttt tgccataatt acctccaaat aatttgttta ttatgtgtat actatatcat
     5641 gtttttttaa tccttaaaac cctcaaaaaa catggtatat gtcaaattat atcgattaga
     5701 atatttttta ctccgttttt cttaaaaata cttagaaaat attattttta attattattt
     5761 tactatataa actgtatttt tttatcaaat ttaattgtat atcttaaatt taatttaaat
     5821 ttcctaaatt aatgttttta aaatctttaa gtaaatatct tattttatca atgatttctt
     5881 tacttccatt taaatattca gattcaatat taatagctaa aataggctca tgtagtgaga
     5941 ttctaattaa aaaccatgat ttagaattat ttatatacgc ctttacacct tcataatttg
     6001 gctctgcaat atttaattct ttatcatttt ttatttttaa tttaatttca cttaaaatat
     6061 tttcaccata ccctttaaaa ttttttgcat ctatatttaa tctaaattct aactgctcac
     6121 tactttctct aaaattactt attattgaat ttaattcttt gccttttctc ttaagaatag
     6181 caagttttat taatattttt gctactaaat aagctccatc atctaaaaaa taattttctt
     6241 ttaaagcagc atgtcctgaa gtttctattg ctatatctac ctcttcacct aaagaattta
     6301 atcttttagc ctcatttata acatttttat atccacgttt aaatctatga tgctttccac
     6361 ctaatccttc tataaatttt tttaatcctt cagaagtaat agaatcagta actactgttg
     6421 tacctggatt ttcttctaaa agaatagcag aaattaaagc tattaaagta tttttattta
     6481 tagctcttcc atctttatct actatagctg ctctatctac atctgtatca aaaataactc
     6541 ctaaatcagc attattttta actactgcat tacttattga tagtatagct tgtttatctt
     6601 ctggattagg tatatgatta gggaaatttc catctggatt taaaaattga cttccactag
     6661 tatcagcccc taaaacttct aatactttat ttacaaaaaa tccacctgct ccatttccag
     6721 catcaactaa tatctttaaa ttctttaaag gagtctcgct ccctgtttta acccttatat
     6781 tattaacaat aatcttacta taatcactta ccaaatcttt aactataatc ttaccttttt
     6841 gagtattact taactcttca ttagtagtaa aatctataat tttatttaac tcctcttttt
     6901 caactccacc atcttttgtg aaaaacttca ttccattata ataaaaaggt aaatgacttg
     6961 ctgttatcat tatagctcca tctactttat atccatccat tattgttgac ataaacattg
     7021 ctggagtagt tgccatatta caatcaataa catccactcc tgtatctatt aaagtattta
     7081 tagctgctga ctttaataaa tctcctgata atcttgaatc cttaccaatg gcaatagtta
     7141 ttttttcacc taactttttt tcttttaaaa acagtgcaaa acctatagct atcctactta
     7201 ccacctcttc tgtaagtgta agttcaaatt ctttattttc catagctatt cctctaatat
     7261 ctgtaccact ttgtagttcc tttaaagtat tcatcttatc actcctagtt ttctcaaaga
     7321 aattatctta tgttaaaaat attgtataat tattatctct taaattttaa tttaattata
     7381 agtcaaatat atatcatata ttttaatact tagatattct attcctaaat ttaatcttaa
     7441 gctcatttat aagttgttct aaattatcct cattattttc ttttatataa tcccactcct
     7501 ctataataaa ttctttagct tcatctaaaa tctttaaaat atattctaaa tttatttttt
     7561 tattatcata tgaaatattt acaattaagt cttcctcatt taaatcaatt ttattaattc
     7621 catttatcat gtctggtatt tcatctatta aataataata ctctctatgc tcttctttta
     7681 acttaaaagg aatatcaaat tttataacac attcaccact taaatccttt aaaactacaa
     7741 ttttaaaact ctttctaaat atagcctgtt ttatcttatt cataatagcc tccaatattt
     7801 tttctttcac tatattatgc tatgcatctt taaaattact tatttctaaa aaatatataa
     7861 aataaaaaaa ctacctcata cgagatagtt ttttattata tatattcctt attctttatt
     7921 tttaagcatt tcagcaatag ctgctatact accaagactt gataaagttt cattaggtaa
     7981 aattaattta ttagaagggc ccttagccat ttcttttaaa gcttctactt gttttaatgc
     8041 tattactctt tcatcagttc ctgattctaa aatagcctta tttacaatct ctatagctgc
     8101 tgcttcagcc tttgcaattt cttctatcgc ttttgcctta ccttcagcct ctaataattg
     8161 agattcttta agaccttcag ctcttctaat attagcttct ttttcagcct ctgctgataa
     8221 aattttagca gttttctctc cttcagcttt agctatatca ctttgctttg ttccttctgc
     8281 ttgtaatatt atagctcttt tatctctttc tgccttcatt tgcttttcca tagcttcttg
     8341 aatttctttt ggagggatta tatttttaat ttcaacagtt aatattttta ctccataagc
     8401 atctgtaact tgatcaacta ttctcaaaag ctccatattt attttatctc ttcctgaaag
     8461 aacttcatct aaagtcatat tcccaactat atttctcata tttgtagttg ttgaatatgc
     8521 tatacctgat ctataatttt ctatattata gaccgcctct tgtgcattaa taactttata
     8581 aaatataaca ttatcaattt gtatatttac attatctttt gtaataactg tctgaggatc
     8641 tatatctaaa atttgttgtt taacagatat tcttcttcgt atatgatcta taaacggaac
     8701 tataaaatgc caacctggtt ctaatatctt atgatattgt ccaaatcttt ctaaaactac
     8761 tacatatcct gtgttaacta tttttattga ccaggctaga agtaatatta taatgattat
     8821 tactattgct aatactattg tcatagcact atctcctatt cttttgttag tatttctgtc
     8881 ttattatttg atttatctat taataattta ttaccttcaa tcccgactac ctcaacttca
     8941 tctcctactt ttaattcctt agctatattc ttaaaagtcc aatatgaacc cttaaatgca
     9001 attaagtttt ctccacttac atcattctct aatataaatc ttatacctat atatttctgt
     9061 tcaagatttt taaactctgc tttattttca ttactattct ttttatactt aatataaaaa
     9121 ataacaatta ctaaagttgt tattaaacca aaaataataa tttgaacttc tacagaaaat
     9181 tttaaaaact ctaaaattat tgaaaataat gctgctattg atatacccaa aaataaaata
     9241 tcagcaatca taaagctaga tagcactgat aacacaagta taatactcca tataatagac
     9301 aaagtctcac ctctttttct tacttaaaaa gcataaatat atattaataa atttataaat
     9361 tattgtaaaa cttacttttt tataatcttt attaaaattc tttaacttta aaacccatta
     9421 ttacatttat ggataatttt ataatatatt ttaatttatt tatgtataat aaagtattgt
     9481 tttcataaat tttgaaaaat aaaaaagtac ctaaattttt agatactttt tgtttaatat
     9541 attatctttt tctataatga tatgaattat aattatgttt tgcagcatta ttagctctaa
     9601 catgattata aacttttcca aatacatatc cacttacagc acccttaact gctgattttg
     9661 caacactttc accaaaactt tcttgatgat attgctgttc ttgttgatat ggtggataat
     9721 aagtttcacg ataaacttct tctcttctat gctctgatat taaagcaatt attaaaagta
     9781 caactattat tatacttgtt attaatataa tttttcttct tctagtcatt tcaaccctct
     9841 ttaaattatt attaaaatcc ttataaactg gcatattaaa tacatattaa aatatttttt
     9901 taattttatc aataaatttt gatagtaaaa aagtataatt tatcaaaaca attaaaataa
     9961 aggagttatc tctaataaga tagctccttt ctcttaaaaa ttatttactt gctactaaaa
    10021 gcatttctct taaaacttta catgcagcag cagttgatgc accactatga tcataatgtg
    10081 gtgataattc atttatatca aaaccaacta tatttgcatc ctttaaaatt ttaattcctt
    10141 ctataatttc tttaaatgtt attccgcctg gttctggtgt tcctgttcca gggaatattg
    10201 aaggatctaa tacatcaaga tctatagtta catatacact cttacctttt aatttttcaa
    10261 ctatttcacc taaagtttct aaatcaaaat gtctagtata cacatgtgat ttaccccaat
    10321 aaatttcatc tctttctcct gatcttatac caaattgata tattcttcca tctccaagaa
    10381 tatcccaagc tcttcttata acactagcat gtgataattt ttctcccatg taatcatctc
    10441 taagatctgc atgagcatca aattgtatta tgtgtaaatc atcatatttt ttgctaagac
    10501 ttcttatatt acctagagta actaaatgtt ctccacctat catacaaggt ttcttaccat
    10561 cagctactat tttatcagca aattcttcaa ttatttctaa tgccttagct gaatttccaa
    10621 atggtaattc taaatctcca gcatcaaaaa acttatagtc ttctaaatct ttatcttgat
    10681 atgggctata tgtttctaaa ccataggaat ctggtctcat tgcttgactc gcaaatctag
    10741 ttcctggtct atttgaagtt gttgaatcaa aaggagctcc ataaataact atttctgatt
    10801 catcatattc attatcacat gacatgaatg taggaatatt tctattcatt tctagcctcc
    10861 tcaagtaaat ttttaacata gtttggtaaa gcaaatgctc ctctatgaat ttctgtgtta
    10921 tagtacttag tttctaatcc aagcttattc cattcatcta tcttatcgct gtttattgga
    10981 tcatatttct ttgaagcaaa tccaaataac cagtgtcctg atggatatgt tgggatatga
    11041 gcttgataaa ctctacatat tgggaaactt tctcttattc tcttatgagc tctcttcatt
    11101 gatttagcat attcagcata atatggactt tcatgttggt taacaagtat tccttcttca
    11161 tttaatgctt taaagcagtt tccatagaat tctttagtga aaagaccttc tcctggacca
    11221 aatgggtctg ttgagtcaac aattattaaa tcatatttgt tttctactcc tcttacaaac
    11281 tttagaccat cttcataata aagatttact ctttcatcat ctaactttga agctgtttgt
    11341 ggtaagtatt ctctacaaac atcaacaaca agcttatcta tttcaaccat atctatattt
    11401 tctatacctg ggtatcttgt aagttctctt actgtaccac catctccagc accaattact
    11461 aatacatttt taatattagg atttgttgcc ataggtacat gaactatcat atcatgataa
    11521 ataaattcat ctttttctgt taccatcatt aatccatcta aagtaaagaa tgttccaaac
    11581 tcttctgaac ggaaaacatc tatttcttgg aattcacttt ttccactata taattgttcc
    11641 ttaactttta ttgaaaatct agcatctttt gtatgctctt ctgtatacca taattccatt
    11701 tttaaatcgc tcctttattt taataccttt attttttctg tattcatatc ttcaagtcct
    11761 gttaaaagac ttcctttgtt ttttgaatat aaaataaaat caatagcttc tctagttata
    11821 agctctcctg gtgatagtat tggaatacct ggtggataac acataataaa ttccccagaa
    11881 attcttcctt cactttcttc tataagtaca tcttctcttt cagaataaaa agctttttta
    11941 ggtgttacct ttaaaatagg acttatatat tcatgatcta ttaaatcctt tttatctttt
    12001 ttatacattc ttcctatttc ataaagagca gctactaatc tttctatatt ataattagta
    12061 tcacctactg aaattatagc taggatattt cctacatcac ctagttcaat ttgtattcca
    12121 tattcatctc ttagaatatc ataaacttca attcctgcaa gtccaatatc taaagtattt
    12181 actacaagct ttgtagtatc aaaatcatat atatctcttc catttataat ttcatctgaa
    12241 aaagcataat aatcttttat tttatttatt tcatttcttg catagtttgc cttttcaaca
    12301 atactattaa taatttcttc tccatgaaga gcaagatttc ttcttgctat atcaagagat
    12361 gacattaaaa gatatgaacc actagttgtc tgagttatat ttattattgt tcttacatag
    12421 tcaactgaca gtctgtctgt atttaataaa agcattgaac tctgagtaag agatccccct
    12481 gttttatgaa cacttacagc tgacatatct gctccagctt ccatagcaga cataggtaaa
    12541 tctttaccaa aataaaaatg tgttccatga gcttcatctg ctaaaacata catattatgt
    12601 ttttttgcaa gctttacaat actctttaaa tctgaacata ttccataata agtaggatta
    12661 tttacaaata tagctttagc atctggatgt tcttttattg ctttttctat atctttaata
    12721 tccataccaa gtgatatacc taatctatta tgtattcctg gatttatata gataggtatt
    12781 gcacctgtta aaattaaagc atttattgct gatctatgaa catttctagg aagaattatt
    12841 ttatcccctt ctttacaaac actcattatc atagcttgaa ctgctgaggt agttccatta
    12901 accataaaga aagcatgttt tgcagaaaat gccttagcag caatttcttc tgcttctttt
    12961 ataacagatg ttgggtgaca aagattatct aggggtttca tagaatttac atctacagct
    13021 aaacaatctt cacctaaaaa ctcccttaat tctgggtttc ctctcccttg cttatgtcca
    13081 ggaacatcaa aaggtactat tttatttttt ttatattcct ttaaagcttc atatatagga
    13141 gctctttctt gctcattttt aaacacagtt tctcctcctt aatataaatt agttcctgaa
    13201 tatatctcta tcatttcctt tgataatctt tctcttatct ctagtctagt acttggagat
    13261 aattcataac tatttactct aaaaagataa ttatcaagat ttatctcttt aagcatcatt
    13321 tttgtatgat aaatattact ttgatataca tttatatctg tagtatcata tctctttaaa
    13381 gtatcttttt ctataaagtt ttgtattgaa gttatatcat gatctataaa atgttttcta
    13441 ccacttatat ctcttgtaaa ccctcttact ctataatcta ttgttataac atctgaatca
    13501 aaactaccta ttaagtaatt taaagcattt agtggagata tttgtccaca agttgaaaca
    13561 tctatatcta ctctaaatgt tgttatatct tcatctggat gaaattctgg ataagtatgc
    13621 acagttacgt gactcttatc taagtgtgct acaacagttt ctctttgctt tccattagca
    13681 taatctaata ttcctttatt acatgaacta tctactaaat catcttctat ttcttcttct
    13741 gatataagaa gagtaacact tgcaccctgt ggttcatagt cttgtttaga tatatttagt
    13801 acactagctc ctattatatt tgttacttca cataaaattt ttgttaatct ctctgaatta
    13861 tactgttcat ctatatattt aatatagtcc tgtttttctt tctctgtttt tgcataacat
    13921 acatcataaa tattaaaact taatgttttt gttaaattgt taaaaccata aagacgaatt
    13981 ttttcgctca attcctcacc tcatcataat tattaataat ttactagtat attatatatt
    14041 aatattcggt aaatttatat aagttttttt cattttttgt tcataaattt aaaaaaacct
    14101 acataagatt gtataaatct tatataggtt actataaaaa ctcaattttt acatttatta
    14161 attccaaaaa tcttttaaaa tttctttatg attgctagag aattcataat tttctaattc
    14221 tcttaatgaa atccatttcc aatttgatat gcttgaatga caagacattc tttcttttaa
    14281 aactgtacta aatactactt tgtcattttc ttcatctaag ctatattctt taaacttagt
    14341 aatatcgaag cctactacat tcaattcttt ttctaaaatt ctattagcgc attgttctgg
    14401 tgattctttc gctctcatac tcttcccaac aattgaccat aacttaggtt ctgttttctt
    14461 aacttttttt tgtattataa gaacattatt aaaatcgtct tttataataa cttcacaatg
    14521 tgtaatttta ctcacaacat taccccctat cagataatta acaaattttt gaaaagctta
    14581 tcaaatttat ctagaatttt tcatacaagc taattatact atatttatcc taataacgtt
    14641 gttaaattta ctttaataaa taaaaaagca ccttaagact aagatgctta ctaaaaatta
    14701 ctcatgaaga ccaaattctc taattataag agttgaccag ttattatttt cctttactat
    14761 ccattcacat tctatatcca tatgtttaag ccatgcattt aatccaaatg ttttctttgt
    14821 tacatttgca gctcttcttc catatatctc ttttatgttt tcaagaagtt cttgttgctc
    14881 tttttcatct aattctttat caagaagagg tcttattaat tcacaacatt ttatatatga
    14941 ctttgcatct tcataatata attcatctgc ataaacctgt ctgtcttgat ttaagtaatc
    15001 catcacttca tttatttcat ctttatttga tagatatttc tttgctattg ctaaagcttc
    15061 taaatctcta tccatttttg aaactttttt ttctaaatta taatgtctca tattatcttc
    15121 cttatctaat attatttatc aaaaatttat gatattttat ttattatacc ataaaaagaa
    15181 tttacattta tttaaaatag tatttcttca caaaagttgc actaattcac tcagaatatt
    15241 ataataatta taatttcaat taaagaaata aagaaaagga ggagctacga attaaatata
    15301 aattaacatt tttaattata tttaaagtgg cagtttataa atggatattt ctaatagaaa
    15361 gctaaaaaaa gctttgaatt tatatgaaaa tggtgaatat gaagcagcac taaaaatttg
    15421 tgaaaaatat cttgaaaaag aatatagtga tgaagaagca ttatatcttg aaggagcaat
    15481 tctatataga cttggtagaa ttgatgatgc tattgttact tggaaaataa atgccgagta
    15541 taataaaaat gctgatgcta taaaacatct tgcttcaata gataaagaaa aaaaggaaca
    15601 ggctttaagt tataataata tacgtgattt acatagtgaa gaaagagaag aaaaagaaca
    15661 agctctacaa gaagaaaata atgaggttat ttctgaaact tttgaaactg aaagagaacg
    15721 tttccctaaa tctgaagtta cagatgaacc tatatctcaa gaatttatag aagaatcacc
    15781 agaattaact gaaattgtac catctactga agtaactgaa ttaactgaaa atacaattca
    15841 tgatgattat gtagaagata tagttgagga aagtaatgac tctaaagaat atcatgtagt
    15901 tgatacaaat gtagatgagc ttattaattc ttctaataca gtagaaacaa atcatccaaa
    15961 aactattgat ttagaggaat ttaagaaaag aattaaacat ctagaatcaa atacttctag
    16021 tgaagaaaat aatgaggaag aagatgatga tacaccttta agagctcaag attttaaacc
    16081 acaaggtaga aatactaata atagtgatat aaaagcttca aagtcaaaaa gaatcgcagc
    16141 tacttctgct ataatagcat taattttaat agctggtgta tcctatgttg caataaaatc
    16201 taataatagc cctaaagttg ctaaaaatga tactactaaa gctgaggata cccctaaacc
    16261 aattacaaaa cctgaggaaa agccagctga tactactgct caaaaaccag ctgatcaaac
    16321 tacagcacca gcagctatgc ttacaccaga gcaagctcaa aatcttataa cagatcttaa
    16381 gtatttaata tctgttaact ctattgataa ggttaatgca atacttcaaa atacacctaa
    16441 agatacagtt ccagctaatg ctatgcctga atatactgca gctgaaaact ttatgaatac
    16501 tacaggagtt aactactatt atgataatgc tatggaaaat tataataatg gtaattattt
    16561 agaagcaata gaatacttca aaaaggctca accttataca actgaaaaat ttaggggtcc
    16621 aactgttgca tatcttatag ctaaatcata tgaaaaactt ggagatataa atacatcatt
    16681 agattattat aaaaaatatc taaaagaata ccctacttct gaaagttata cacctgaagt
    16741 actttatcat cttgcattat attataactc acaaaaagat actgtagagg caaagaaata
    16801 tgcaaatatg cttaattcaa cattctcaag ttcaatgtat aacaacgata atataagtaa
    16861 aattataaat gaacaataaa aaagttagga aatctatatg atttcctaac ttttattttt
    16921 aatttatata aataaatcta taactgtaac tattcctaat gaacatgttg atatatatat
    16981 tattataagt ataacttttt cccacttttt aagagcaaat tccttaggca acgttttcca
    17041 tgcaagtgct attaaaaatc caagtactat aggtaataaa agtgaattta atacttctac
    17101 ccctattgta agtgatacaa gcggcattcc tgacaatact attgcagctg atagaactat
    17161 tgttattata taaactgcat aaaatactgg tgcttctttt attgtattat ttaaacttgc
    17221 tggtacattt aataattctc ctattgacca tgaaatagct aatgacacaa ctatcgctgc
    17281 aacaagtcct gctcctacaa tccctgcagc aaatagtacc ttaccagcta aactacctac
    17341 aaatggtgtt aaagcattaa ctatttgttc cacactattt aaaggtgcat taggatttgt
    17401 cttacctatt gttgcagcaa ctataagaat aacagctatt actattattt gagtaactac
    17461 tgaacctatt gctgtatcaa ttctagacat ttttatctct tcttttctta ctttcttttc
    17521 cacaattgca ctttgttggt agaatatcat ccatggcata attacagctc caacattagc
    17581 tgaaattaat aaccaataat caccattcat taatggttga tttacaaatc cgttagcaat
    17641 ttcacttaaa tctggttttg acataaaagc aactattata aataataatt caaataatcc
    17701 aataaaaata gctgtttttt ctaccttttt ataatttcct gttgttgtta ttaatattaa
    17761 aattaatgct gctgccggaa ctgatatcca tttaaatatt ccaaataaaa ctccaactcc
    17821 tagtatccct gtaaattcag taactaaagc tcctataact gctattagta atgttaaaac
    17881 tgaaaatatc tcccactttc ttccgaatac ttcttttatt aattctccat gaccttttcc
    17941 tgttactatt cctaatctat ttgtaagttc ttgtacgaaa taaactattg gtatcagtat
    18001 taattgaaga cctattaatt tatatcccca ttgtgctcct gattgagcag ctgttactac
    18061 tgatcctaca tctgtatctg ctaacattac taaaagtcct ggccctaagg ctgcaagtag
    18121 catccacagt ttacttcttc ttttattact tatcttttgt tcgaaattag actccatttt
    18181 cactcctcct aaagtctagt taattgcagt aattagatta tcaccccaaa gattattatg
    18241 caaattttat gaaaaaataa atcaattgaa agtaattatc atacttaatt aatttccttt
    18301 aaaaagctct attttttatt aatttaataa ttatttaatt caaaaataaa ttaatattat
    18361 aatatttgta tatcattatt aaactatata tttttctatt aatttatata ttataattta
    18421 taaatataaa ctactttaaa tatcaaaaat aaaaagctag aaaacatata aatgttttct
    18481 agcttttata ctctaatatt ttatataaat aaatctataa ctgtaactat tcctagtgaa
    18541 caaattgata catatattat tataagcaca actttttccc aagtttttag tgaatattct
    18601 ttaggtaatg tcttccaagc aagagctatt aaaaatccaa gtactatagg taataataat
    18661 gagtttaatg tttcaacagc tattgtaagt ggtacaagtg gtattcctga taatactatt
    18721 gcagctgata caactattgt tattatataa actccataaa atactggtgc ttcttttatt
    18781 gtattattta aacttgctgg tacatttaat aattctccta ttgaccatga gatagcaagt
    18841 gatacaacta ttgctgcaac aagtgctgct cctataattc ctactgcaaa taataattta
    18901 cctgcaaagc ttcctacaaa tggtgttaat gcatcaacta attgttgtac actatttaaa
    18961 ggtgcattag gatttgtttt tcctattgta gatgcaacta taagcattat agcaattact
    19021 attatttgag taactactga acctattgct gtatcaactt tagacatttt taaatagctt
    19081 tttggtaact tcttttctac aactgcactt tgttgataga atatcatcca tggcataact
    19141 actgctccaa cattagctga aattagtaac cagtatcctc catcctttaa tggttgattt
    19201 acaaatccca tagctatatc atttaaattt ggttttgata taattgctat tattataaat
    19261 actaattcaa ataatcctat aagaatagct gtcttttcta cttttttata atttcctgtt
    19321 gttgttatta aaattaatac tattgctgct aatggaactg ttacccattt agatactcca
    19381 aataaaattc caactccaag tattcctgta aattctgtaa ctaaagcacc tataactgct
    19441 actaataatg ttacaactga aaatacttcc cacttcttgc cgaatgcttc tttaattaat
    19501 tctccatgtc cttttcctgt gactattcct aatctatttg taagttcttg aacaaaatat
    19561 actattggta ttagtattaa ttgaagtcct attagtctat aaccccattg agctgctgat
    19621 tgagctgctg ttactattga tccaacatct gtatctgcaa gcatcactaa aaccccaggt
    19681 cctaaaatac ttaataatgt taatatctta ttttttcttt tataatttat ttcatttcta
    19741 ctatcatttc tatctatatt aatctccatg ttaaacacct cctgatgtct acttgttgtt
    19801 aaatatagat taacatttag taaatttttg tgcaaaccat ccaaaaaatc aataactgaa
    19861 aatgattttc attttcaatt atttttttat taaaattaaa attatattaa cacattaaaa
    19921 atttataaaa tgaaatagta ttaatttcat aaactttata tatcaactat agagtttgaa
    19981 tttctgtctc agatatatct ttataattaa aacctcctat attttataaa tatataaaat
    20041 aagatcaaat acttatataa taaaaaaatt atagattttt ttatttatca aaaaagagtt
    20101 atcttttaga taactctttt tttgatgatt tatttagctc tatttaaatt atacagcttt
    20161 tatatgatta tctcccacta atatagaaaa tctgctttct accgtttaca ggattttctg
    20221 atatataact atctactcca aaaacctctt ttatagtttc actagtgaaa atctcatcta
    20281 ctgttccact ttttaaaatt tcaccttgtt tcattacaat aatataatca caatacattg
    20341 ctgatatatt catatcatgt aatgctgcaa atacagtaac atttagatct ttaattatat
    20401 ccataagctg tatttgataa gtaatatcta agtgatttgt aggttcatct aaaattataa
    20461 aatctgtatc ttgaactaaa gctctagcta taaatgctct ttgtttttct ccacctgata
    20521 atgtattaaa atttctatct ttatattttt caagccctac tcttttaatc atcccatcca
    20581 caagctttat atcttcttta gaataatctt caaacattga tttataagga tatcttccca
    20641 ttttaacaac atcttctaca gtaaaatcaa attgtgttga actttcttgt gcaagtatag
    20701 ctaattcttt tgctatttct tttgatttca tttcattaat ttctttacca tctatatata
    20761 tttttccctt attaggttta taaactctat atatattttt taataaagtt gatttacctg
    20821 atccattagg tcctattatt cctacaaatt tacctttggg tatttctaag tctatacctt
    20881 ttagtatttt ttgctttcca atttcatatt caagtccttc aatctttaac ttcattattc
    20941 attacctcca aatgaataat tatttttagc tattaaccat aagaagaatg gtccgccaat
    21001 tatcgctgtt attattccta ttggtaattc tctaggagca aatataactc tagctattat
    21061 atctgaaaca actaagaata tagctcctaa aagtgatgat aaaattaata tcttcttatg
    21121 actacttcca acaagtcctc tagatatatg tggaactaca agtcctacaa atccaatagc
    21181 tccaacaact gaaactaaaa ctgaagttaa aaatgttgcc aataatatta ttatagattt
    21241 tataagttta acattcatac caagaacaat tgcacttgtg tctccaaata atagtaagtc
    21301 taatgaattt gataagaata aacttataat caaaactaaa attaatataa caataggtaa
    21361 aattatatta ctccatttag ctccaccaag gcttcccatt atccagaaca tagctgctct
    21421 tgcttgatta gaattttctg ctgaataaat tataaaattt gttatagctg aaaatattgt
    21481 agatattgca agccctgata aaacaagcct tgtagttgat gaaactcttc cccactttgt
    21541 accaataata aaaactaatg ctccacaaag cacggaccct aaaaatgctc caagagttac
    21601 tccaaatata gctccaccta ttactattac aaaaacagct ccagctgaag ctcctgaaga
    21661 tattcctaga atatatggat ctgctattga atttcttgtt acacattgca ttaaaattcc
    21721 acatattgca agccctgctc ctgttactgc tgcaaggata actcttggca tccttatatc
    21781 aaatattata gtttctatta cattgttcca actaacatca aaaatattta ttccaactat
    21841 tttatttaat acagcttcat aaactatatt gaattttata tgtgtactac ctatagatat
    21901 agcaaaaatc atacttacta taagaatagc agctaatata attatagcta atccataact
    21961 agttttagat tttttcatta tttaacatcc ccatagaaca tagtattcat ttctttaata
    22021 gcctttggtg ctcttattcc tggtgataaa tcagctaaat ctatagtgaa tatcttatta
    22081 ttcttaaccg cattaacatt tttaaatgca ggatttgtct taagaagatt tattttttca
    22141 tctacacttt gaggttctga taaatatcta gtaactataa taatatctgg attttttgct
    22201 gctatacttt caaatgatac tgtattccat tgattattta aatctccaaa gatatttttc
    22261 ccaccagcaa gagttataag attgtttgca aatcctccac caacaacata tgcatcctta
    22321 tctcctgaat catacacaag tactgatggt ttcttatctt ctggtacagt tttatttcta
    22381 tcttcaactt ctttaatttg tgctttcata tctgcaacta ctttttgtgc tctatcttct
    22441 acattaaata ttttaccaag ttgatcataa tctttatata catcttctat tgttgcatta
    22501 ccttgtaaag ctgattctac ataaggagct attccttctt gttctaattc ttctggagtt
    22561 ccaaccccct tagcacttag tgattgtaac catcctgaaa caaaatctgg ttttaaagct
    22621 aagaagcttt cttttgatat ttggtgtcct tctgtaactt taagttgagg tattttatca
    22681 taagcctctt tatattctgg aagaattgga ttatctagaa gtgctgttcc aaccattcta
    22741 tctccaagtc ctaatgataa taatgtctca gtcataaact gtgataaagt aactgctctt
    22801 ttgggagctg acttaatagt aacatctact ggtttattta ttccgtcgtt atatacatat
    22861 tttacttctt tatatgttga tgattgatca gctattttaa cctcattttt attttttact
    22921 gcaacattat atctgaatat tccaaatcca actactgcag cagctactac tatacctgcg
    22981 attataactt taattttttt attcatcttc tctctctctt tctcttcaac ttttgtaatt
    23041 tctccgcaat ttatataact attttgtaac ttttacgaaa tttattgtaa cctaatatta
    23101 ataaaaagta aaaacaccaa aaatatatat ttttatattt aaatatacat tttttattaa
    23161 ttttaatgta tatagatata ctttctataa agtttaataa attgtgacta aattaacaac
    23221 aagattcatc ttttaaatga tattgcttta tcaattaata acttaatctc tataaaataa
    23281 ttacaaaata aaaagatata aaaacttata gtttaagctt ttataccttt aaaaaattta
    23341 ttaatttaat aataattaat tataaattag attattaaat cattaatatt attcttttat
    23401 tcatctttag agcttttatt attatctttc ataaatttag ttaagctatc aaagagcata
    23461 ttcttttttc cttttaaaaa agctaataat ataggtagca ttataagcgg ccctacactt
    23521 cctgctatta tatcttccat agtatctaaa agacttccac cttgagaatc aaaattaaat
    23581 aactgatctc cagcaaattc ccacatctcc caacaggcag tcattgcaat agaaaataaa
    23641 aaagtataag ttactataag tataggtttt acattctttg tttcataatt attttgaacc
    23701 ataaaaactg tatatgcaac taaaaagact actccccctg aaactaaatg taaaaataaa
    23761 tcccaccatt caaatttaaa ataaaagcta ttcatttttc ctagaaacat agctataaat
    23821 ataaaaattt gaattataaa atttaaatat ttaggaatct taattttaga tatctttata
    23881 attacccttg gtagtgcaat aacaactaaa gtacaaaatc cattaaatat ataatcatta
    23941 cttttattga taattccata aattatatat atagatgtga ttatatatag g
//
