LOCUS       c00005_NZ_CABK..       24724 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKWO010000005.1 Clostridium mediterraneense isolate
            MGYG-HGUT-01553, whole genome shotgun sequence.
ACCESSION   c00005_NZ_CABK..
VERSION     c00005_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:28:21
            Original ID  :: NZ_CABKWO010000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 634436
            Orig. end    :: 659160
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24724
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[644436:649160]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14724
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..24724
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24724
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             1323..2030
                     /locus_tag="ctg5_538"
                     /transl_table=11
                     /translation="MSKALKIASDLERKIHGGVYKEGDKLPTEMQLCAKYDVSRMTIRK
                     ALEKLIDHGWLYRIQGSGNYVKKDVNRKSYSGAARTFGLTQYLHNKKIESKMLDFKIIA
                     ADKDLSEKLYCKEGDIIYYVERLRIVEDEPYVLEKSYFIEKYVRGLSEKIIKSSIYSYI
                     ENDLGYKIQQSTDNVTAKEADANLAEILNCEVGSALLLNESTVYLDNGQAFEYSLDIHR
                     GDRANFIMIRNRY"
     CDS             2181..3248
                     /locus_tag="ctg5_539"
                     /transl_table=11
                     /translation="VLYSLILAGGKGTRLYPLSRSKEPKQFLKILNNKSFLANTVERVS
                     PLIPNENIYVITNKDYEEKVKEELSNINSENIFTEPANKETATCIGLAAIKLLKKDKDA
                     VMVVLPSDHYIKEDENYLETVKQAVTIADKKKLIVTMGIEPTRPEMGYGYIEMGERING
                     VIPTYKVARFTEKPNLEVAKDFILKGTYLWNSGMFVFRADVILREIEKYIPTLYKCLSE
                     IYRHIGLEDEEEIIKNQYSLVDGISIDFGVMQKTRRAAVIKCDFSWDDIGSFKALSRFL
                     QTNDTNAVSKNVYLDDSENCCIFGRERLVIGFGLKDLVVVDTGDVLLLMDKNKDQEIKH
                     LLSKINKIDDYKDYL"
     CDS             3624..4193
                     /locus_tag="ctg5_540"
                     /transl_table=11
                     /translation="MDDKIVDFSKLKEKVRDKDINDFENYIYNLYFKMAEGKMNMMQFT
                     KEITSYMQENNISEEKFVNIQKEMLSRYGVSMDDIDGQLKGMGIDPATMTGMNSKAYED
                     MRKVMGFQEKYKTRLSSKTVTTYRIKNEKNDIEIYLEGNNVLIKSSKDIDLQDIELNEF
                     LCSYKKTLEDSSLSIELCSNIQTYIY"
     CDS             4246..4842
                     /locus_tag="ctg5_541"
                     /transl_table=11
                     /translation="MMANTHIVMAKHIYSNLNLKEKRVVSYRNFLYGNIKPDMVSKYKL
                     KKHYMDESFDMVMDKIKVLSSLSDNEIRKLPEIVSFSQELGVVCHFLCDFFCIPHSERW
                     EFKHSMNKHVKYEKDLSNFAKEFKLPRERAKVFGFYNIEEFILRAHEFYREDSSFVNDL
                     VFSSYVCNSVVDYIIDCIEFNSSIGGRLVNSIGIS"
     CDS             4975..5610
                     /locus_tag="ctg5_542"
                     /transl_table=11
                     /translation="MENKTTTEPVYKQIALDLAGRIYNEDVKVGEKISGRSTLASNYNV
                     SPETVRKAIKLLEDMDVVRSSRGSGVKIVSKENAYEFIERFHSIESVTTLKQNINKLFE
                     EKQQIENNINCMIQKIVDYSNKLRYTNPLTPIEVEIPDDSDIIGKSISEAKFWQNTGAT
                     IIGIRRNGELIISPGPHLIFEKSDVILVVGNDGILDSIDKYFEKKKLS"
     CDS             5726..6172
                     /locus_tag="ctg5_543"
                     /transl_table=11
                     /translation="MYFQLAYNKSEHMSSCSYDNGKGIFAMNKKEDKILESCEVKAIHQ
                     EVVDKVQTDLPDDEVLYDLAELFKVFGDSTRIKILYSLFQAEMCVCDIGIILGISQSAV
                     SHQLRVLKQARLVKYRREGKVVYYSLDDDHIKRIFNEGLNHIKE"
     CDS             6222..8879
                     /locus_tag="ctg5_544"
                     /transl_table=11
                     /translation="MNEVKLYLEGLDCAGCAAKIEEKTDKLPEVKEASLNFATKALVFQ
                     LENGTNEEEVVTTIKEIVRKLEPDVVVKRDKVKESNVSVCADNSCLTNEMKITFENLFC
                     AGCAGKIEEKTGKLPEVKEANLNFTNMSMFVELKDGQSDMEVYEKVKEITKKLEPDVVV
                     KYERESKSVEASKTLKLNLTGLDCAGCAGKIEEGTAKLPEVKEANLNFATKVIVIDLND
                     AKDYEKVKADVKEIVRKLEPDVVVSEVKEEVVYDDAPVSTEKKEEKVESGFSAYNITRF
                     IIGVVLFGIAEWAGFSDTISNIIFIISYIILGYPTVLKALKNIVRAKNIFDENFLMMIA
                     SIGAFAIGEHSEAVAVIMFYEIGEMFQGYAVNNSRKSISSLMNIKPDFARVIRDGKEST
                     ISPYAVKVGEIITVRAGERVPLDGIVIEGSGSVDTSALTGESLPRSIKNNDEVLAGCIN
                     LNGVIKLRVTNDFKESTLSKILELVENAGNKKAPTEKFVTKFSRYYTPVIVGIAVFLAI
                     VPPLVLPDATFIEWLKRALVFLVVSCPCALVVSIPLGFFGGIGSASKNGILVKGGNYLE
                     ALNNVKTVVFDKTGTLTEGKFKVLKINAKNYSNEELIKIAAHSEYLSNHPIAKSIVAEY
                     KGEINKDSISDYEEIAGRGVSLKLDGAKVFAGNAKLMSENNIKFKETDELGTVVHFAID
                     GNYAGSILIGDMVKSDSKETIKGLRSLGIKTVMLTGDNKKAGEAVAKNLELDEVHAELL
                     PQDKVTELEKILSNKGEKDNVIFVGDGINDAPVLARADIGIAMGGVGSDAAIEAADVVI
                     MKDEPSKIIQAIKIAKRTRVIVWQNIIFALGIKFIVLLLAAFGFATMWEAVFADVGVAI
                     LAILNSMRVLINKK"
     CDS             9189..9824
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_545"
                     /sec_met_domain="CoA_binding (E-value: 1.4e-25, bitscore:
                     86.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEKKKLISMAVIKRLPKYHRYLNELMNNDVDRISSKELSEKIGFT
                     ASQIRQDLNCFGDFGQQGYGYNVKALYNEISNILGLSREYRAVIIGAGNIGQAIANYNQ
                     FRKLGFTIEGIFDANPKLLGIQIRDVAIQDIDELEGFLERNQIDIGIICVPKVNAQKVA
                     DKLISKGVKGIWNFAPIDLNTPDDVTVENVHLSESLLTLVYLLNEKNN"
     CDS             10001..10783
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_546"
                     /sec_met_domain="EC1_2-faecali (E-value: 2.3e-86, bitscore:
                     286.2, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFNNVLLEKEGNIAILTINRPKALNALNSETLQDLDKALEQLEN
                     ESDIYAVILRGAGDKSFVAGADISEMKNLNEEQGKEFGLLGNKVFRRLENLDKPVIAAI
                     SGFALGGGCELAMACDIRIASEKAKFAQPEAGLGITPGFGGTQRLPRLVGTGVAKEMIY
                     TGRIVKADEALRIGLINKVVSPELLMEEAKKLADMISINAPIAVKLCKDAINRGTQVDI
                     DSAIVIEANDFGKCFDTEDQKEGMSAFIERREKNFKNK"
     CDS             10814..11953
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_547"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.7e-53, bitscore:
                     177.9, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-27, bitscore:
                     92.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8.1e-36, bitscore:
                     120.2, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTAEQKLMRQMVRDFAINEVKPIAAEIDETERFPMENVKKM
                     AKLGLMGIPFSDEFGGANGDTLSYIIAVEELSKVCGTTGVILSAHTSLCASLIDQFGNA
                     AQKAKYLTPLAKGEKLGAFCLTEPGAGTDAAGQQTVARLEGDNYILNGSKIFITNGGVA
                     DTFIIFAMTDKSQGTRGISAFIVEKEFPGLSVGKVEQKMGIRASSTTEIIMENCIVPKE
                     NLIGKLGKGFGIAMKTLDGGRIGIAAQALGIAAGALEEAVNYTKERKQFGRSLSAFQGL
                     QWMMADMDVKVEAARNLVYKAAWLKEKGLPYSVEAARAKLYAAEVAMDVTTKAVQIFGG
                     YGYTKEYPIERMMRDAKITEIYEGTSEVQKMVISGSLLR"
     CDS             11971..12750
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 169;
                     E-value: 3.4e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_548"
                     /sec_met_domain="ETF (E-value: 1.2e-50, bitscore: 169.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCLKQVPDTTAVKIDPVTGTLIRNGVPSIINPEDKHALEAA
                     LCLKDEYGAKITVISMGPLQAKDALREALCMGADEAILITDRAFAGADTLATSKALAGA
                     IKKLDYDIIFAGRQAIDGDTAQVGPEIAEHLGIPQVTYVQDVKVEEDGLLINRALENGY
                     ELIKVEGKVLLTAIKELNEPRYMHAKYIFATANKEIITWTADDIDVDKAELGLKGSPTK
                     VKKSMTKEAKSSGEIINKSADEAVTYIMAKLKEKHYI"
     CDS             12771..13778
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 161.4;
                     E-value: 7e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_549"
                     /sec_met_domain="ETF (E-value: 2.6e-48, bitscore: 161.4,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 3.7e-37, bitscore:
                     123.3, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLADYNGVCVFAEQREGVMQKVSLEILGEGRKLADKLGTKLIAL
                     VLGHEIQGMGKILGEYGADEVLVVDNPLLKDYTTDGYTTAICEVLNDIKPGIFFIGATF
                     IGRDLGPRVAARLSTGLTADCTSLDVDVETGDLLATRPAFGGNLMATIACPDHRPQMAT
                     VRPGVFSKLPANNNGYTVSTIQVNLKDSDIRTKIVKVVKENKDIKDISEARVLVAGGRG
                     VGSKENFDMLKALADEFGGSIAASRAAIEKGWVDKDYQVGQTGKTVRPNIYIACGISGA
                     IQHVAGMQDSDLIIAINKDESAPIMKVADYAIVGEVSKVVPELISQLKNIKEAM"
     CDS             13876..14724
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_550"
                     /sec_met_domain="HCDH (E-value: 1.1e-34, bitscore: 116.0,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 2.5e-69, bitscore: 229.9,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIFVLGAGTMGAGIVQAFAQKGYEVIVRDIKQEFVDRGIAGIE
                     KSLTRLVSKEKITEEAKNDMLSRISGTVDMEMAKDCDLVIEAAVENMDIKKSIFSELDK
                     ICKPETILASNTSSLSITEVASATNRPDKVIGMHFFNPAPVMKLVEIINGMATSKETFD
                     AVKEVSENIGKSPVEVAEAPGFVVNRILIPMINEAAGILAEGIASEEDIDTAMKLGANH
                     PMGPLALGDLIGLDVCLAIMDVLYKETGDSKYRAHSLLRKYVRAGWLGRKSGRGFHNYA
                     K"
     CDS             14953..16653
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     325.3; E-value: 4.4e-99)"
                     /gene_kind="resistance"
                     /locus_tag="ctg5_551"
                     /transl_table=11
                     /translation="MIKEFIKYYKPHKKLFILDILAAFLMALCDLVYPMLTRNIMNDVI
                     PNKNLRLLWVFSIILFFIFIFKAGLNYFMQYQGHILGVRMQGEMRKDIFVKLQKLPNKY
                     FDDNKTGVIMSRIINDLNEISELAHHGPEDLFISIVLILGSFGILLSINIELTLIIFAI
                     LPIGIFFTLRQRKKMISAFRDTRIKTGEVNARIENSISGIKVTKSFSNAEYEIDRFEDC
                     NNVFKLARIKAYKTMAEYFSGMFLFIDLLELIVLIGGGYFTYIGRINIGDFVAYILYIK
                     MFLQPIRKLINFNEMLQDGMTGFQRLNEIVTESEEEEKRTAKELKNVKGEITIEDLSFN
                     YDGVNDILKDFNLKIEAGKKIALVGSSGGGKTTLCNLIPRFYEFDSGDIKIDGISVKDV
                     TLESLRNNIGIVQQDVFLFTGTIRENIEYGKLGATDEEIIEAAKKACLHDFVMSLEDGY
                     DTYIGERGVKLSGGQKQRISIARVFLKNPSILILDEATSALDNITEGEIQKSLEDLSKN
                     RTTLIVAHRLSTIRNADEIVVIGKEGIIEQGTHEMLMDNEGFYSTLNSI"
     CDS             16799..17359
                     /locus_tag="ctg5_552"
                     /transl_table=11
                     /translation="MDAATHSSIMYTFQDMHTPVLNTIMLWITRIGTDGLIWLVLGLIF
                     LITKKYRKAGFMMFFGSSINFVLVEVLKHIVKRPRPFMTLPGLHVIGPVPHSYSFPSGH
                     ASSAFVGAFIIAYYFRAWAIPAYALAVAIAFSRVYLLVHYPSDVIGGAIIGTISVILAF
                     FFYRVILKRWFNGILRGLGIEKK"
     CDS             17590..18789
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     380.5; E-value: 2.3e-116)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_553"
                     /sec_met_domain="Fe-ADH (E-value: 8.5e-115, bitscore:
                     380.5, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRFTLPRDIFFEKGSLEQLKTLEGKKAVIVIGGGSMKRFGFLDK
                     VLNYLEEANIETKIIDGVEQDPSVETVFNGAKVMSEFNPDWIIAMGGGSPIDAAKAMWV
                     FYEHPEKTFDDIKDPFTIPKLRNKAKFLAIPSTSGTATEVTAFSVITDYKTGIKYPLAD
                     YNITPDIAIVDPELAETMPQKLVANTGMDALTHAIEAYVAGLHSAFSDPLAMEAIEIIR
                     DNLIDSYNGDMKARENMHYAQCLAGMAFSNALLGITHSMAHKSGAVFHEEGKEENELKH
                     IPHGCANAIYLPYVIDFNKKACMDRYAKIAKRLELKGNTDEELVDSLTAMIKDMNVKMN
                     IPETIKEFGINEDEFKAKVELIAERAVSDACTASNPRTINKEEMKKLYEATFYGTKVDF
                     "
     CDS             18907..19797
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_554"
                     /sec_met_domain="NAD_binding_1 (E-value: 1.1e-05, bitscore:
                     23.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFKITKKQELAQNIYLMDILAPRVAKSANPGQFVIVKINETGERI
                     PLTICDYDKGEGTVSIVFQTIGESTKRMQELEVGDEFKDFVGPLGRQSELIDENLEDLK
                     NKKILFVAGGVGTAPVYPQVKWLNKNGVKADVIVGAKNKNMLILENEMREVAGNLYIAT
                     DDGSYGKKGLVTNLIEDLVINEGKKYDLVVTIGPMIMMKFVCLLTKKLNIPTIASLNPI
                     MVDGTGMCGACRVTVGNEVKFACVDGPEFDGHLVNFDEAMRRQQIYKTEEGRKILKEAE
                     GDTHHGGCGNCGGEN"
     CDS             19797..21185
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_20"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:Dihydroprymidine dehydrogenase domain II, 4Fe-4S
                     cluster (Score: 143.7; E-value: 6.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_555"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-33, bitscore:
                     113.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_20 (E-value: 2.2e-43, bitscore:
                     143.7, seeds: 204, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVNLNRTPVREQEAKVRANNFKEVCLGYDLDLAINEARRCLNCK
                     NPKCVGNCPVAIDIPGFIKNLKDGNIKEAAEVIAKASALPAVCGRVCPQEVQCEGKCVL
                     GIKGEAVAIGKLEKFVADYVRENNIELDIEINKNNKKVAVVGSGPAGLTCAGDLAKMGY
                     DVTIFEALHEAGGVLVYGIPEFRLPKDSVVKAEIENVKKLGVKIETNVIVGRTVTIDEL
                     LEEEGFEAVFIGSGAGLPKFMGIKGENANGVFSANEFLTRNNLMKAYKNEYDTPVKIGK
                     KVAVVGGGNVAMDAARTALRLGAEVHIIYRRSEEELPARKEEVHHAKEEGVIFDVLTNP
                     IEIIEDENGWVKGMKCIKMELGEADSSGRRRPVPVEGSEFIMDIDNVIMSLGTSPNPLI
                     SSTTKGLETNKWECLVADEESGATSKEGVFAGGDAVTGAATVILAMGAGKKAAIGIDKY
                     IKNR"
     CDS             21688..21990
                     /locus_tag="ctg5_556"
                     /transl_table=11
                     /translation="MKFTLREQERLMMVVAADVAKRRRDRGLKLNYPESVAIITDFITE
                     GARDGKTVEQLMSEGRELIKAEEVMEGVPEMIHSIQVEVTFPDGTKLVTVHDPIQ"
     CDS             22016..22327
                     /locus_tag="ctg5_557"
                     /transl_table=11
                     /translation="MIPGEYILKDEKVVMNEGTTSIKLRVVNTGDRPVQVGSHYHFAEV
                     NTKLEFDREAAYGKRLDIPSGTAVRFEPGDEKEVSLIDIQGSRRIFGLNDKVNGPLDK"
     CDS             22358..24073
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_558"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.6e-71, bitscore:
                     237.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFEMNRKSYVDMFGPTVGDSFRLADTNLFAQIEKDLTKHGDECK
                     FGGGKTLRAGMGVNITESRNNPLVADLIISGATIIDYTGIYKADIGIRDGKIMAIGKGG
                     NPDIMDDVDFIVGVATEALAGEGFIITAGGIDTHVHYINPDEVTVGLQGGITTLFGGGT
                     GPADGSNAVTATPGPFNIKRMLEAAEHLPVNIGILAKAGAHDDAPGVEQIAAGAAGFKV
                     HEDWGATRGCIDKALEMADKYDIQVSIHTDTLNEYGFLEDTIDAIAGRCIHTFHTEGAG
                     GGHAPDIIKAAQYNNVLPASTSPTLPYTHNTIAEHLDMLMVCHHLDPKIPEDVAFADSR
                     IRHQTIEAEDVLHDMGVISMTSSDAIAMGRIGEVVTRTWQVAHHMKNLRGPLEGDSEYN
                     DNNRIKRYVAKYTINPAIAQGVGEYIGSVEVGKYADLVLWTPQFFGVKPEMIIKKGLIS
                     MAVSGDPNASIPTIQPRILRKMYYAEGKGIAQSCITFVSKLAWENGIKEELGLEREVLP
                     VKGIRNLTKKDMKLNDATPKIEVDPQTYIVSVDGEPIVAEPATELPMTQKYFLF"
     CDS             24157..24612
                     /locus_tag="ctg5_559"
                     /transl_table=11
                     /translation="MILNKILGNINDDIDTQGLHVEKLYLRSDELLKRINRVVSDHGHE
                     YGISIDKGEVLKDGDILYKDEKNMVVVSVKSDDVLIIKPETITEMGRIAHNLGNRHLPA
                     QFRDGMMILEYDKLVEDLLKQEAIKYSREHVTLEKAFRHVEFGHKHV"
ORIGIN
        1 gaagtttcta tggtatatga agaaataaat ttaagtataa aatctcttag aagatggagt
       61 aaaaaacaaa aggtaaaaag tcctttagca gttcttcctg ctaagagtta tatttattat
      121 gaaccttatg gaactgttct tattatagga ccttttaatt atccatttca gcttaatttt
      181 tcaccacttg ttggagctat aagtgctggg aatacagcta tgattaaacc atcagaatca
      241 gtaatggaaa ctactaatat aattaaagaa ataatagagg aaacttttga tgagaattac
      301 atagcatatg taaatcctga aaaaggtaaa gaagtagtag aggaactttt aaagtttaag
      361 tatgattata ttttctttac tggaagtgtt acagtaggaa aaattattat gagagcagca
      421 gcagacaatc ttattcctat aactttagaa cttggaggaa agagtccttg tatagttgat
      481 agtgatgcaa aattaagact tgcagctaga agaatagttt ggggaaagct tataaattca
      541 ggtcaaactt gtgttgcacc agattatatt tatgttcata aaagtataaa agataagttt
      601 ttacaaacct tagctgatga aataaaaatt caatatggag agaatacaag attttcagaa
      661 gattatccaa gaatggttaa tgaaagagag tttgaaaggg taattagtta tataaacaaa
      721 gaaaaaattt attttggtgg aaatagtgaa aaagaagatc tttatataga gccaactgta
      781 ttatcaaatg ttaattggaa tgatgatgtt atgcaaagtg aaatttttgg acctttattc
      841 ccagtattag aatttgagga tataaatgat gttatagaaa ttgtaagtga tagagaaaag
      901 ccacttgctt tatattattt ctcagaaagt agagataaga ttaattatat tttaaaacat
      961 acaactgcgg gtggagttac aattaatgat actttaatgc atgtatcatc tgctttctta
     1021 cctttcggag gcgttggtaa tagtgggata ggaagttatc atggaaaaga gagctttaca
     1081 acattttctc ataagaaatc agttttaaat agagcaactt ggtttgatat gccacttaga
     1141 tatgcaccat ttaaggataa attatctcta gcaaagaaaa ttttaaaatg atatctaaag
     1201 taaataaaat gtgtatttta caaataaagt aataaatgta tagacaaagt aactttttcg
     1261 ttttagaatt atatgtaata gattaacatt atatatattt ttaggtaatg cggaggggta
     1321 ttatgtcgaa ggctttgaaa atagcatctg atcttgaaag aaaaattcat ggtggtgtat
     1381 ataaagaagg ggataagctt ccaactgaaa tgcagctatg tgcaaaatat gatgtaagta
     1441 gaatgaccat taggaaagct ttagaaaagc ttattgatca cggttggctt tatagaattc
     1501 aaggaagtgg aaattacgtt aaaaaagatg taaatagaaa aagttattca ggagctgcta
     1561 gaacgtttgg actaacacag tatttacata ataaaaagat tgaaagtaag atgttagatt
     1621 ttaaaattat tgcagctgat aaggatttat cagaaaaatt atattgcaaa gaaggcgata
     1681 taatttatta tgttgagaga cttagaatag tagaagatga accatatgtt ttagaaaaaa
     1741 gttattttat agagaaatac gttagaggtt taagtgagaa aataataaag tcatcgattt
     1801 attcatatat tgaaaatgac cttggttata agatacaaca atcaactgat aatgttacag
     1861 caaaagaggc agatgctaat ttagctgaaa tattaaattg tgaagttggt tcagcacttt
     1921 tattaaatga atcaacagtt tatttagata atggacaagc ttttgagtat tcattagata
     1981 ttcatagggg agatagagca aattttataa tgattagaaa tagatattaa tcagattgaa
     2041 tagggtaaga ttttatatag aagcttactc tatttttatt ttgttaagaa aaataagaat
     2101 aaataaagat aaaaatagca cactgtaaaa tttaagttca tagaatgaag tataagcaag
     2161 ttatggagtt gaaggcaggg gtgctttatt cattaattct agctggagga aagggcacaa
     2221 gactatatcc tctttcaagg agcaaagaac ctaagcagtt tttgaaaata ttgaataata
     2281 agagtttctt agctaataca gtggaaaggg taagtccact tattccgaat gagaatattt
     2341 acgttatcac aaataaagat tacgaagaaa aggttaagga agagctttca aatataaatt
     2401 cagaaaatat atttactgaa ccagctaata aagaaactgc gacctgcata ggtcttgctg
     2461 caattaagct tttaaagaaa gataaggatg cagtaatggt tgttttgcct tcagatcatt
     2521 atattaaaga ggatgaaaat taccttgaaa ccgtaaaaca agcagtgact atagctgata
     2581 agaaaaaact tatagtcact atgggaatag aacctaccag accagaaatg ggatatggtt
     2641 atattgagat gggtgagaga ataaatggtg taataccaac ttataaagtg gcaaggttta
     2701 ctgaaaaacc taatcttgaa gttgcaaaag attttatatt aaaaggaact tatctctgga
     2761 atagtggtat gtttgttttt agagcagatg tgattcttag ggaaatagaa aaatatattc
     2821 caactcttta taaatgttta agtgaaatat ataggcatat aggcttagaa gatgaagaag
     2881 agataataaa aaatcaatat tcattagttg atggaatttc tatagatttt ggagtaatgc
     2941 aaaaaactag aagagcagca gtgataaaat gtgatttttc ttgggatgat ataggaagtt
     3001 ttaaagcact aagtagattt ctacaaacaa atgatacgaa cgcagttagt aaaaatgttt
     3061 acttagatga ttcagaaaat tgttgtatct ttggtaggga gaggctagtt ataggctttg
     3121 gacttaaaga tcttgtagta gttgatactg gtgatgtgct tttattgatg gataaaaata
     3181 aagaccaaga aataaagcat ttattatcaa agataaataa aatagatgat tataaagact
     3241 atttgtaata aaaggagaag ggctgtatag cagctttttt ccttttttgt atgttaatta
     3301 agatttaaac tttagaaaat atttaattta attgatatat cactaataga agtgttattt
     3361 atttggataa aggtaaaagt taagctataa aataataatt tttggtatat attaaatata
     3421 ggaagattta tttagttttt atttatatat tgagataaaa tattatgatt aataatattt
     3481 taaaactata tatgataaag tagatattta atattcttag taaagaagta tgaaattaaa
     3541 aatttagcta ataacaaaaa gaaattcttt tgtggtaaaa tatatagtga ataaattctc
     3601 tggaaaacta ggaggaatgg aaaatggacg acaagattgt agatttcagt aaattaaaag
     3661 aaaaggttag agataaagat attaatgact ttgaaaatta tatatataat ctttatttta
     3721 aaatggctga aggtaaaatg aatatgatgc agttcacaaa ggaaattact tcatatatgc
     3781 aagagaacaa tatttcagaa gaaaagtttg ttaacattca aaaagaaatg cttagtagat
     3841 atggagtaag catggatgat atagatggac agcttaaagg aatgggaatt gatccagcaa
     3901 caatgactgg tatgaattca aaagcttatg aagatatgag aaaagttatg ggcttccaag
     3961 aaaagtacaa aactagactt tcaagcaaaa cagtaactac ttatagaata aagaatgaaa
     4021 agaatgatat agaaatatac ttagaaggga ataatgtact tataaagagt tctaaagata
     4081 ttgaccttca agatatagag cttaatgaat ttttatgttc atataagaag actttagaag
     4141 attcttcttt aagtatagaa ctatgttcta atatacaaac atatatatat taagctttta
     4201 gatatattta ttctctttaa ataaatttga ctggagatgc acattatgat ggcaaatacc
     4261 catattgtta tggcgaaaca tatatattca aatttgaatc tcaaggaaaa gagagtagta
     4321 agttatagaa attttcttta tggaaatata aagccagaca tggtatctaa atataaatta
     4381 aaaaaacatt atatggatga atcttttgat atggttatgg acaagataaa ggttcttagt
     4441 tctttatctg ataatgagat aagaaaacta cctgaaatag ttagctttag tcaagaactt
     4501 ggagttgtat gtcatttttt atgtgacttt ttctgtattc cacatagtga aagatgggaa
     4561 ttcaagcata gtatgaataa acatgttaag tatgaaaaag atttatccaa ctttgcaaaa
     4621 gaatttaaat tacctagaga aagagctaag gtatttggtt tttataatat agaagagttt
     4681 atattaagag ctcatgaatt ttatagagaa gatagctctt ttgttaatga cttagtattt
     4741 tcaagttatg tatgcaacag tgttgttgat tatataattg attgtataga attcaatagt
     4801 agtattggag gaagactagt aaattcaata ggaatatcgt aattaggtaa gccacttttg
     4861 tatgttatta tatacgaagg tggtttattt taatgttgat agcaaataac ttgaaagcgt
     4921 atgataaaaa aaggtaaaat agtattaata aatatgagag agtgagggag taagatggaa
     4981 aataaaacga caacagaacc tgtctataag caaattgctt tagatttagc aggtagaatt
     5041 tataatgaag atgttaaagt cggagaaaaa atttcaggta gatcaacttt agcaagtaat
     5101 tataatgttt caccagagac agttagaaag gcaattaaac ttttagaaga tatggatgtt
     5161 gtacgttcaa gtagaggcag tggggtaaag atagtttcta aggaaaatgc ttatgaattt
     5221 attgaaagat ttcactctat tgaaagtgta actactttaa agcaaaatat aaataaatta
     5281 tttgaagaaa agcaacaaat tgaaaataat ataaattgta tgatacaaaa aatagtagat
     5341 tattcaaata aattaagata tacaaatcct ttaactccta tagaagttga gataccagat
     5401 gattcagata ttataggaaa gagtatttca gaagctaagt tctggcaaaa tacaggggcg
     5461 actattattg ggataagaag aaatggtgaa ttaattattt ctccaggtcc tcatcttatt
     5521 tttgaaaaat ctgatgttat tttagttgtt ggaaatgatg gaattttaga tagtatagat
     5581 aaatattttg agaagaaaaa gttatcctaa aaaaggataa ctttttttat tatatttaca
     5641 taagataaga gaaaaataat aaatgtttat ataatttcta gagtactata gaaaaattat
     5701 aaaaagtata aagaaataat tgacaatgta ctttcaatta gcatataata aaagtgaaca
     5761 tatgagcagt tgttcatatg ataatggaaa ggggattttt gctatgaata aaaaagaaga
     5821 taaaatttta gaaagctgcg aggtgaaagc aattcatcaa gaggtagtag ataaagttca
     5881 aacagattta ccagatgatg aagtactata tgatttagcc gaattattta aggtttttgg
     5941 agatagtaca agaataaaaa ttttatattc attattccaa gcagaaatgt gtgtgtgtga
     6001 tattggaata atacttggaa taagtcaatc agctgtatca catcaattaa gagttttaaa
     6061 acaagctaga cttgtaaaat acagaagaga aggaaaagta gtgtattatt cactagatga
     6121 cgatcatatt aagagaatat ttaatgaagg tctaaatcat attaaggaat agatttttag
     6181 agaaatgatt aaataaattt taggaaagga tggctatttt tatgaatgaa gttaaacttt
     6241 atttagaggg cttagattgt gcagggtgtg cagctaagat agaagaaaag actgataaac
     6301 ttccagaagt aaaagaagca agtttaaact tcgctactaa agctttggtc tttcaattag
     6361 agaatggcac taatgaagaa gaagttgtta ctactattaa agaaatagtt agaaaattag
     6421 agccagacgt tgtagtaaaa agagataagg ttaaagaaag taatgtaagt gtatgtgctg
     6481 ataattcatg cttaacaaat gaaatgaaga taacatttga aaatcttttc tgtgcagggt
     6541 gtgcaggtaa gatagaagaa aagacaggta agcttccaga agtaaaagaa gctaatctta
     6601 atttcacaaa tatgtctatg tttgtagagc ttaaagatgg acaatctgat atggaagtat
     6661 acgaaaaagt taaagaaatt actaaaaagc ttgaaccaga tgtagttgtt aaatatgaaa
     6721 gagaaagtaa atcagtagaa gcatcaaaaa cacttaagct taatttaaca ggtcttgatt
     6781 gtgcagggtg tgcagggaag atagaggaag gaacagcaaa acttccagaa gtaaaagaag
     6841 caaacttaaa ctttgcaact aaagtaatag ttatagatct taatgatgct aaggactatg
     6901 aaaaagttaa agctgatgtt aaagaaatag taagaaaact tgaaccagat gtagtggtta
     6961 gtgaagttaa agaagaagta gtttatgatg atgcaccagt atcaacagaa aagaaagaag
     7021 aaaaggttga atcaggattt tcagcttata atataacaag atttattata ggtgttgtat
     7081 tatttggaat agctgaatgg gctggtttct cagatactat tagtaatatt atatttataa
     7141 taagttatat tattttagga tatccaacag ttctaaaagc tcttaagaat atagttagag
     7201 ctaagaatat atttgatgaa aacttcttaa tgatgattgc aagtataggt gcttttgcaa
     7261 taggtgaaca ttcagaagca gttgcagtta tcatgttcta tgaaataggt gaaatgttcc
     7321 aaggatatgc agttaataac tcaagaaagt caattagctc acttatgaat attaaacctg
     7381 attttgctag agttattaga gatggaaagg aatcaactat ctcaccatat gcagttaaag
     7441 ttggagaaat cataactgtt agagctggtg aaagagttcc tttagatggt attgttattg
     7501 aaggtagcgg aagtgttgat acatcagcat taacaggtga atcacttcca agatcaataa
     7561 aaaataatga tgaagtttta gcaggatgta ttaatttaaa tggagttatc aaattaagag
     7621 ttactaatga ttttaaggaa tcaactcttt ctaagatatt agagcttgtt gaaaatgcag
     7681 gaaacaagaa agctccaaca gaaaaatttg taactaagtt ctcaagatac tatacaccag
     7741 taattgttgg aatagcagta ttcttagcta tagtaccacc attagtactt ccagatgcaa
     7801 catttattga atggttaaag agagcacttg tattcttagt tgtttcatgt ccatgtgctt
     7861 tagttgtttc aatcccatta ggattctttg gtggaattgg ttcagcttca aagaatggta
     7921 tccttgttaa aggtggaaac tacctagaag cattaaataa tgttaagaca gtagtattcg
     7981 ataaaacagg aacacttaca gaaggtaagt tcaaagttct taagataaat gcaaagaatt
     8041 attcaaatga agagttaata aaaatagctg ctcacagtga atatttatca aatcacccaa
     8101 ttgctaagtc aatagtggct gagtataaag gtgaaataaa taaagactct atttcagatt
     8161 atgaagaaat agctggtaga ggtgtttcac ttaaattaga tggagctaaa gtatttgcag
     8221 gtaatgcaaa acttatgagt gaaaataata ttaagtttaa agaaacagat gaacttggaa
     8281 cagttgtaca ctttgctatc gatggtaatt atgcaggaag catattaatc ggagatatgg
     8341 taaagagtga ttctaaggaa acaatcaagg gattaagatc acttggaatt aagactgtta
     8401 tgcttacagg agataataag aaagcaggag aagctgttgc taagaactta gaacttgatg
     8461 aagttcatgc agaattatta cctcaagata aggtaacaga acttgaaaaa atattatcaa
     8521 ataaaggtga aaaagataat gtaatatttg ttggagacgg tattaatgac gctccagtac
     8581 ttgcaagagc tgatatcgga attgctatgg gtggtgttgg ttcagatgcg gccatagaag
     8641 cagctgatgt tgttattatg aaagatgaac caagtaagat tattcaagca attaagatag
     8701 ctaagagaac aagagttatt gtatggcaaa atattatctt tgcacttgga attaagttta
     8761 tagtattatt acttgcagca tttggatttg caacaatgtg ggaagcagtt ttcgcagacg
     8821 ttggggttgc tattttagca atattaaatt caatgagagt tttaataaat aaaaaataaa
     8881 aaaatagtca aaagtttact tttattttaa aaaagttaaa aaatttgacg aaattttatt
     8941 gacattttaa ttaactttaa atataatcag tatataagaa tacgttcagg tagagggtat
     9001 aacagttata ctatttatct taatgaggct tgtacattgc gatatatcgc tttgtatgag
     9061 ccttatttta tatttgatat atattcatta aatcaatatt aaaaagttat ttaaatatgt
     9121 gtttaaatta tgataatata taaataatgt gttatatatt taacaagata aaaaagagag
     9181 gtgccacagt ggaaaagaaa aagctaatat ctatggcggt tataaagaga ctaccaaaat
     9241 accatagata tctaaatgaa ttaatgaata acgatgtaga tagaatttct tcaaaagaat
     9301 taagtgaaaa gattggattt acagcatcac aaattcgtca agatttaaat tgttttggag
     9361 attttggaca acaaggatat ggatataatg taaaggcatt atataatgaa attagtaata
     9421 ttttagggtt aagtagagaa tatagagctg taataatagg agctggaaac attggacaag
     9481 cgatagcaaa ttataatcaa tttagaaagc ttggatttac tatagaaggt atttttgatg
     9541 caaatcctaa gcttttagga atacaaataa gagatgttgc tatacaagat atagatgaat
     9601 tagaaggttt cttagaaaga aatcaaattg atattggtat aatatgtgtt cctaaagtta
     9661 atgcgcaaaa ggtagcagat aaattaataa gtaaaggtgt taaaggaatt tggaactttg
     9721 ctcctataga tttaaatact ccagatgacg ttacagtaga aaatgttcat ttaagtgaaa
     9781 gtcttttaac tttagtgtac ttattaaacg aaaaaaataa ttaataaaaa aatatttgga
     9841 taaaaatact aaaatatcca aaaatatatt gcaaatacaa ttaatagcac ttataattta
     9901 attgaagttt atctaaactt caattatttt ttttgcaatt tgttaagttt ataacaaata
     9961 actttgggta taaaagagaa aggtattaag ggggagaaaa atggaattta ataatgttct
    10021 tcttgaaaaa gaagggaaca tagctatttt gactattaat agacctaagg ctttaaatgc
    10081 attaaactca gagactttac aagatttaga taaagcatta gaacagcttg aaaatgaaag
    10141 tgatatatat gcagtaattt taagaggtgc aggtgataaa tcatttgtgg caggagcaga
    10201 tatatctgaa atgaaaaatc ttaatgaaga acaaggcaaa gaatttggtc ttttaggaaa
    10261 taaagttttt agaagacttg aaaatttaga taaaccagta attgcagcta tttctggatt
    10321 tgcattaggt ggaggctgtg agcttgctat ggcttgtgat ataagaatag ctagtgaaaa
    10381 agcaaaattt gctcaaccag aagctggact tggaattact ccaggctttg gcggtactca
    10441 aagacttcca agacttgttg gaacaggtgt agcaaaagaa atgatttata caggtagaat
    10501 agttaaagct gatgaagctc ttagaatagg acttattaat aaagttgtat ctccagagtt
    10561 attaatggaa gaagctaaaa agcttgctga tatgatatct ataaatgctc caatagctgt
    10621 taagctttgt aaggatgcta tcaatagagg aacacaagta gatatagata gtgcaatagt
    10681 tatagaagct aatgattttg gtaaatgttt tgatacagaa gatcaaaaag aaggaatgtc
    10741 agcttttatt gaaagaagag aaaagaattt taaaaataaa taagggtatt gaaaataagg
    10801 ggaggctaaa ttaatgaatt ttgaattaac tgcagagcaa aaattaatga gacaaatggt
    10861 tagagatttt gctataaatg aggttaaacc tatagctgct gaaatagatg aaacagaaag
    10921 atttcctatg gaaaatgtga aaaaaatggc caagcttggc ttaatgggaa ttcctttttc
    10981 agacgagttt ggtggagcaa atggtgatac attgtcatat ataatagctg ttgaagaatt
    11041 atcaaaagta tgtggaacaa ctggagttat tctttcagct catacatctt tatgtgcatc
    11101 attaatagac caatttggta atgctgctca aaaagctaag tacttaactc cacttgcaaa
    11161 gggcgaaaaa ctaggagctt tttgccttac agaaccaggt gcgggtacag atgcagcagg
    11221 tcaacaaact gttgctagat tagaaggaga taattatatt ctaaatggaa gtaagatatt
    11281 tataacaaat ggtggagtag cagatacatt tataattttt gctatgacag ataagagcca
    11341 aggaactaga ggaatatcag cttttatagt tgaaaaagaa ttcccaggat tatcagttgg
    11401 taaggttgaa caaaaaatgg gtattagagc ttcgtctaca actgaaataa taatggaaaa
    11461 ttgtatagtt ccaaaagaaa acttaattgg taagcttgga aaaggctttg gtatagcaat
    11521 gaaaactctt gatggaggta gaattggtat agcagctcaa gcactaggaa tagcagctgg
    11581 agctttagaa gaagcagtaa attatacaaa ggaaagaaaa caatttggaa gatcactttc
    11641 agcattccaa ggtcttcaat ggatgatggc agatatggat gttaaagttg aagcagctag
    11701 aaatttagtt tataaggcag cgtggcttaa agaaaaagga cttccatatt cagttgaagc
    11761 agcaagggct aaattatatg cagcagaagt agctatggat gtaacaacta aggctgttca
    11821 aatatttgga ggatatggct atactaaaga atatcctatt gaaagaatga tgagagatgc
    11881 aaaaataact gaaatttatg aaggaacatc agaagttcaa aagatggtta tttcaggaag
    11941 tctgttaaga taatttaggg ggattaaaat atgaatatag tagtttgttt aaaacaagta
    12001 ccagatacaa cagctgttaa gatagatcct gtaacaggaa cattaattag aaatggagtt
    12061 ccatcaatta ttaatccgga agataaacat gctttagaag cagcattatg tttaaaagat
    12121 gaatatggag caaaaataac tgtaattagt atgggaccac ttcaagcaaa ggatgcttta
    12181 agagaagctt tatgtatggg agcggatgaa gcaatattaa ttactgatag agcatttgct
    12241 ggagctgata cacttgcaac atcaaaagct ttagctggag ctataaagaa attagattat
    12301 gatataattt ttgccggaag acaagctata gatggagata cagctcaagt tgggccagaa
    12361 atagcagaac atttaggaat tcctcaagta acatatgttc aagatgttaa agttgaggaa
    12421 gatggattat taataaatag agcattagaa aatggatatg aacttataaa agttgaaggg
    12481 aaagttcttt taacagcaat taaagagtta aatgaaccaa gatatatgca tgctaagtat
    12541 atttttgcaa cagcaaataa ggaaataata acttggacag ctgatgatat agatgttgat
    12601 aaagcagaac ttggacttaa aggatcacct acaaaggtta agaaatcaat gactaaggaa
    12661 gctaagagtt caggagaaat aataaataag tcagcagatg aagcagtaac ttatattatg
    12721 gcaaaattaa aagaaaaaca ctatatctag tttaaggggg agaatttatt atgaatttag
    12781 cagattataa tggagtttgc gtattcgctg aacaaagaga aggggttatg caaaaagttt
    12841 ctttagaaat tttaggtgaa ggaagaaaac ttgcagataa gctaggaaca aagctaatag
    12901 ctttagtttt aggacatgaa attcaaggaa tgggtaaaat tcttggagaa tatggagcag
    12961 atgaagtttt agttgtagat aatccattac ttaaagacta tacaacagat ggatatacaa
    13021 cagctatttg tgaagtttta aatgatataa aaccaggaat atttttcata ggagctacat
    13081 ttataggtag agatttaggg cctagagtag ctgcaagact ttcaacagga cttacagctg
    13141 attgtacaag tttagatgta gatgttgaaa ctggtgatct tcttgctaca agaccagcat
    13201 ttggtggaaa cttaatggct acaatagctt gtccagatca taggccacaa atggcaacag
    13261 taagaccagg agttttctca aagcttcctg ctaataataa tggatatact gtttcaacta
    13321 ttcaagtaaa tctaaaggat tcagatatta gaactaagat agttaaagta gtaaaagaaa
    13381 ataaagatat aaaagatatt tcagaagcta gagttcttgt tgctggtgga agaggagttg
    13441 gatcaaaaga aaactttgat atgttaaaag ctcttgcaga tgagtttggt ggttcaattg
    13501 cagcttcaag agcagctata gaaaaaggtt gggtagataa agattatcaa gttggacaaa
    13561 ctggtaaaac tgttagacct aatatttata tagcttgtgg tatttcagga gctattcagc
    13621 acgttgctgg aatgcaggat tcagatttaa ttatagctat aaataaagat gaatctgcac
    13681 ctataatgaa agttgctgat tatgcgatag taggagaagt ttcaaaagta gtaccagagc
    13741 ttattagtca acttaaaaat attaaagaag caatgtagaa tttattcaaa ttttgattat
    13801 ggtataaaac aaaattaata taagaaaaga gtttgagttt aaactctttt ctaaaaatat
    13861 ttgggggtat tgagaatgaa gaagattttt gtacttggtg ctggaacaat gggagcaggc
    13921 atagttcaag cttttgctca aaaaggatat gaagttattg ttagagatat aaaacaagaa
    13981 tttgttgata gaggaatagc tggaattgaa aagagcctta caagacttgt ttctaaagaa
    14041 aagataacag aagaagctaa aaatgatatg ctttcaagaa tttcaggaac agtagatatg
    14101 gaaatggcta aagattgtga tttagttatt gaagctgctg ttgaaaatat ggatataaag
    14161 aaatctattt tctcagagtt agataaaatt tgtaaaccag aaacaatact tgcttcaaat
    14221 acatcatcat tatcaataac agaagttgca tcagcgacaa atagaccaga taaagtaatt
    14281 ggaatgcatt tctttaatcc agctccagtt atgaaacttg ttgaaatcat aaatggtatg
    14341 gcaacatcaa aagaaacttt tgatgctgtt aaagaagttt ctgaaaatat cggtaagtca
    14401 ccagtagaag ttgcagaagc tcctggattt gtagttaata gaattcttat tcctatgata
    14461 aatgaagccg ctggaatatt agctgaagga atagcttcag aagaagatat tgatacagct
    14521 atgaaacttg gtgctaatca tccaatggga cctttagctt taggggattt aataggactt
    14581 gatgtatgtc ttgctatcat ggatgtttta tataaagaaa caggagatag taaatataga
    14641 gcacacagtc ttttaagaaa gtatgttaga gctggatggc ttggaagaaa atcaggaaga
    14701 ggattccaca attacgctaa ataaaaatta ggtaaagtta aattagattg aagtattata
    14761 gaagctatca gtgaaagata gcttctttta tttattatat agaagatatt atttttaatt
    14821 agtaaggtat agcatataat taaatattac aatcaaattt taaatacttg ataactatta
    14881 tttgttaaaa ttgataatca ttacatgtta ggttataatt tatataagat taatcaaact
    14941 aagggggaaa atatgattaa ggaatttata aaatattata aaccacataa aaaattattc
    15001 atattagata ttttggctgc gtttcttatg gctttatgcg atttagttta tcctatgctt
    15061 acaagaaata ttatgaatga tgtaatacct aataaaaatc taagattatt atgggtattt
    15121 tcaataattt tattttttat atttatattt aaggcaggac ttaattattt tatgcagtat
    15181 caagggcata ttttaggggt tagaatgcaa ggggagatga gaaaagatat ctttgtgaag
    15241 cttcaaaaac tacctaataa gtattttgat gataataaga ctggtgttat aatgtctaga
    15301 attataaatg atttaaatga aatatcagaa cttgcgcatc atggaccaga agatttattt
    15361 atatcaatag tacttatatt aggttctttt ggaattttac tttctataaa tatagagctt
    15421 actttaatta tttttgcaat tttaccaata gggattttct ttactttaag acaaagaaag
    15481 aaaatgataa gtgcttttag agatactaga atcaaaacag gtgaagttaa tgcaagaata
    15541 gaaaatagta tatctggaat taaagtaaca aaatctttct caaatgctga atatgagata
    15601 gatagatttg aggattgtaa taatgtattt aagcttgcga gaataaaggc ttataaaact
    15661 atggctgaat atttctcagg aatgttttta tttatagatt tattagaatt aattgtttta
    15721 ataggtggag gatactttac ttacattgga agaataaata ttggtgattt tgtagcctat
    15781 atattatata ttaagatgtt tttacaacct attagaaaac ttataaactt taatgagatg
    15841 ttacaagatg gtatgacagg attccaaaga ttaaatgaga tagttactga atcagaggaa
    15901 gaagaaaaaa gaacagcaaa agagcttaaa aatgttaagg gtgaaataac aatagaagat
    15961 ttaagtttta attatgatgg agttaatgat attctcaaag attttaattt aaaaatagaa
    16021 gcaggaaaga aaattgcttt agttggatct tctggtggag gaaaaactac tttatgtaat
    16081 ttaattccta gattctatga atttgatagt ggagatataa aaattgatgg aattagtgtt
    16141 aaggatgtaa ctcttgaatc acttagaaat aatataggta tagttcaaca agatgtattt
    16201 ttatttactg gaactataag agaaaatata gagtatggaa aattaggagc tactgatgaa
    16261 gaaattatag aagcggcaaa gaaggcttgt cttcatgatt ttgttatgtc tcttgaagat
    16321 ggatatgata cttatattgg tgaaagagga gttaagcttt caggaggaca aaagcaaaga
    16381 atatctatag ctagagtatt cttaaagaat ccttcaatat taatattaga tgaagcaaca
    16441 tctgcacttg ataatattac tgaaggtgaa atacaaaaat cattagaaga cttaagtaaa
    16501 aatagaacaa cattaatagt tgctcataga ttatctacta ttagaaatgc tgatgaaata
    16561 gttgttattg gtaaagaggg aataatcgaa caaggaacac atgaaatgct tatggataac
    16621 gaaggatttt atagtacttt aaacagtatt taataaaagg aaaagtattt tttgttaaaa
    16681 gtttagattt tatattaaca atatagacaa gctgttaaaa ataatataat atacttatag
    16741 acaataagtg aaaattcatt aaaggtttaa acaaaagaga aatttgggag gaaacaatat
    16801 ggatgcagca actcatagta gcattatgta tacatttcaa gatatgcata caccagtttt
    16861 gaatactata atgctatgga ttactagaat aggaacagat ggtcttatat ggttagtatt
    16921 aggattaata ttcttaataa caaaaaaata tagaaaagca ggatttatga tgttctttgg
    16981 atcatcaata aactttgttt tagtagaagt tttaaaacac atagttaaga gaccaagacc
    17041 atttatgaca cttccaggtc tacatgtaat agggcctgtg ccacattctt attcattccc
    17101 ttcaggacat gcatcatcag catttgtagg ggcatttata atagcttatt actttagagc
    17161 atgggcaata ccagcatatg cacttgcagt agctatagca ttttcaagag tgtacttatt
    17221 agttcactat ccatcagatg ttataggtgg agctattatt ggaacaataa gtgttatatt
    17281 agcattcttc ttctatagag ttatacttaa acgctggttt aatggaattc ttaggggact
    17341 tggaatagag aaaaaataat taagtttaaa taattaggac tgtttcagat aaatgaaaca
    17401 gtccttttaa tttatttttt atgtttataa taattaaaaa atcttatcat aatcataaat
    17461 ctttataaaa aatagtaaaa aattttaaaa ttttggataa attgaataaa attttatatt
    17521 aaagaggata tatatataat gaaatagaat aattaatgtg aaaaaaatta tgtttaagag
    17581 ggttgattta tgaagagatt tactttacca agagatatat tttttgagaa aggctcatta
    17641 gaacaattaa agactttaga aggaaaaaag gctgttatag ttattggcgg aggttcaatg
    17701 aaaagatttg gcttcctaga taaggtgtta aattacttag aagaagcaaa tatagaaaca
    17761 aagataattg atggcgtaga acaagatcca tcagttgaaa cagtttttaa tggtgctaaa
    17821 gttatgagtg aatttaatcc agattggatt atagctatgg gaggaggatc accaatagat
    17881 gctgcaaaag ctatgtgggt attttatgaa catccagaaa aaacttttga tgatataaag
    17941 gatccattta ctattccaaa gcttagaaat aaagcaaaat ttcttgctat accatcaact
    18001 tcaggtacag caacagaagt aacagcattt tctgttataa ctgattataa aacaggaatt
    18061 aaatatcctt tagctgatta taatataact ccagatatag caattgtaga cccagaactt
    18121 gcagaaacaa tgccacaaaa attagttgct aatacaggta tggatgcttt aactcatgct
    18181 atagaagctt atgttgctgg attacattct gcattttcag atcctttagc tatggaagct
    18241 atagaaatta taagagataa tttaattgat tcttataatg gagatatgaa agcaagagaa
    18301 aatatgcatt atgctcaatg tcttgctgga atggcattct caaatgcttt attaggaatt
    18361 acacatagta tggctcataa atcaggagct gtattccatg aagaaggtaa agaagaaaat
    18421 gaattaaaac atataccaca tggttgtgct aatgcaatat atctaccata tgttatagac
    18481 tttaataaaa aagcttgtat ggatagatat gcaaagatag caaaaagatt agaattaaaa
    18541 ggtaatactg atgaagagtt agttgattca ttaacagcta tgataaaaga tatgaatgtt
    18601 aagatgaata ttccagaaac tataaaggaa tttggaatta atgaagatga gtttaaagct
    18661 aaagtagaat taattgctga aagagcagtt tcagatgctt gtacagcatc caacccaagg
    18721 actattaata aagaagaaat gaaaaaatta tatgaagcta cgttctatgg aacaaaagta
    18781 gatttttaaa gttttggcat taagagtttt ctcttgatgc ctttaatata tttgtgatat
    18841 caatattgaa taaaaaatgt aaaaaatgta taattttaat taattataaa tataggggga
    18901 attaaggtgt ttaaaattac taaaaagcaa gagttagcac aaaatatata tcttatggat
    18961 attttagctc caagagtagc taaatctgct aatccaggtc agtttgtaat tgttaagatt
    19021 aatgaaacgg gagagagaat cccattaact atttgtgatt atgataaagg ggaaggaact
    19081 gtcagtatag tttttcaaac aataggtgaa tcaactaaaa ggatgcaaga acttgaagtt
    19141 ggtgatgaat ttaaagattt tgtaggacct ttaggtagac aatcagagct tattgatgaa
    19201 aatttagaag atttaaaaaa taaaaaaata ttatttgtag caggcggagt tggaacagca
    19261 ccagtttatc cacaagttaa atggttaaat aaaaatgggg taaaagctga tgttatagtt
    19321 ggagcaaaaa ataaaaatat gcttatttta gaaaatgaaa tgagagaggt tgcaggtaat
    19381 ttatatatag cgacggatga tggttcttat ggtaaaaagg gacttgtaac taatttaata
    19441 gaagacttag ttattaatga aggtaaaaaa tatgatttag tagtaactat aggacctatg
    19501 ataatgatga aatttgtttg tcttcttact aaaaaattaa atattcctac tatagcgagt
    19561 cttaatccta taatggttga tggaactggt atgtgtggag cttgtagagt aactgtagga
    19621 aatgaagtta agtttgcttg tgttgatgga ccagaatttg atgggcattt agttaacttt
    19681 gatgaagcta tgagaagaca acaaatttat aagactgaag aaggaagaaa aatacttaaa
    19741 gaagctgaag gtgatactca tcatggtgga tgtggaaact gtggaggtga aaattaatgg
    19801 ctgtaaattt aaatagaact cctgttagag aacaagaagc taaggtaaga gctaataatt
    19861 ttaaagaagt ttgtcttgga tatgatttag acttagcaat aaatgaagct agaagatgtt
    19921 taaactgtaa aaatcctaaa tgtgtaggaa attgcccagt agctattgat ataccaggtt
    19981 ttataaaaaa tcttaaagat ggaaatataa aagaggcagc agaagtaata gctaaagcat
    20041 cagctcttcc agcagtatgt ggcagagtat gtccacaaga agttcaatgt gaagggaaat
    20101 gtgtcttagg cataaaagga gaagctgttg ctattggtaa gttagaaaaa tttgttgcag
    20161 attacgttag agaaaataat atagagcttg atatagaaat taataaaaat aataaaaaag
    20221 tagcagtagt aggaagtgga ccagctggac ttacttgtgc tggggatctt gcaaagatgg
    20281 gatatgatgt tacaatattt gaagctttac acgaagcggg tggagtttta gtttatggta
    20341 taccagaatt tagattacct aaagattcag tagtaaaggc tgaaatagaa aatgtgaaga
    20401 aattaggagt taaaatagag actaatgtta tagtaggaag aacagttaca attgatgaac
    20461 ttttagaaga agaaggtttt gaagcagtat ttattggatc aggtgctgga cttccaaagt
    20521 ttatgggtat aaaaggtgaa aatgcaaatg gagtattttc agcaaatgaa tttttaacaa
    20581 gaaataacct tatgaaagca tataaaaatg aatatgatac tcctgttaaa ataggtaaaa
    20641 aagttgcagt tgttggtggg ggaaatgttg ctatggatgc tgcaagaact gctttaagac
    20701 ttggagcaga agttcatata atttatagaa gaagtgaaga agaattacca gcaagaaaag
    20761 aagaagtaca tcatgctaaa gaagagggag taatatttga tgttttaact aatccaattg
    20821 aaattataga agatgaaaat ggttgggtta aaggaatgaa gtgtatcaaa atggagcttg
    20881 gagaggctga tagttcaggg agaagaagac cagtacctgt tgaagggtca gaatttatta
    20941 tggatattga taatgtaatt atgtctcttg ggacatcacc aaatcctcta ataagctcta
    21001 caactaaagg tcttgaaaca aataagtggg agtgtcttgt agcagatgaa gaaagtggag
    21061 cgacatcaaa agaaggagta tttgcagggg gcgatgcagt tactggagca gcaactgtta
    21121 ttttagcaat gggagcagga aaaaaagctg caataggtat agataaatat attaaaaata
    21181 ggtaatggaa atactttctt gtaaaagaaa taatgattat aaaaaacaga ttttttatat
    21241 tataaaaagt ctgttttttt gttataaaat gatagttttt tgttgtaaaa agataaataa
    21301 taacactagc agaatatttt aaataaaggt gaaatttata tattgtttat caattcctag
    21361 taataaatat tatcttttat taaaaaagct aaatttaaat aaaaagttaa aattatgaga
    21421 cctatttaaa taataaaata aaaacaatcg aaatttgacg aatttaatac aaaaaggtat
    21481 tatttattca taaactaatt caaaatttga gttgggttaa attatattaa taatcgataa
    21541 tttaaaagaa taataatatt tcttttggat aaactatttt tgaattaatt tagaacttaa
    21601 atttttttat aatttagtaa ttcaatttta aattatgttt ttttaagtta ttgttgagtt
    21661 aatgaattta aaaaggagga ataatcaatg aagtttacat taagagagca agaaagactt
    21721 atgatggttg ttgcagctga tgtagctaag agaagaagag acagaggatt aaaacttaat
    21781 taccctgaat cagtagctat aatcactgat tttataacag aaggtgctag agacggtaaa
    21841 actgttgaac aattaatgtc agaaggaaga gaattaatta aggctgaaga agttatggaa
    21901 ggtgttccag aaatgattca ctcaattcaa gttgaagtta cattcccaga tggaacaaag
    21961 cttgtaacag ttcacgatcc aatacaataa ttttaaaaaa aaggaggttt caatgatgat
    22021 accaggagaa tacattttaa aagatgaaaa ggtagtaatg aacgaaggta caacaagtat
    22081 taaactaaga gttgtaaata caggagatag accagttcaa gtaggatcac actatcactt
    22141 tgcagaagtt aacacaaagt tagaattcga tagagaagca gcatacggta agagattaga
    22201 tataccatca ggtacagctg taagatttga accaggtgat gaaaaagaag tatctttaat
    22261 agatatccaa ggttcaagaa gaatatttgg attaaatgat aaggttaacg gaccattaga
    22321 taaataattt aaaatatata aagaggaggt caatgtcatg agttttgaaa tgaatagaaa
    22381 atcatatgtt gatatgttcg gaccaacagt aggagacagt ttcagacttg cagatacaaa
    22441 cttatttgca caaatagaaa aagatttaac aaagcatgga gatgaatgta agttcggtgg
    22501 tggtaagaca cttagagctg gtatgggagt taacataaca gaatcaagaa acaacccatt
    22561 agtagctgat ttaattattt caggagctac aatcatagac tacacaggaa tatacaaagc
    22621 agatatcggt atcagagatg gaaaaatcat ggctatcggt aaaggtggta acccagacat
    22681 catggatgat gtagacttta tagtaggggt tgctacagaa gcattagctg gagaaggatt
    22741 catcataaca gctggtggta tagatacaca cgttcactac atcaacccag atgaagtaac
    22801 tgtaggttta caaggtggta tcacaacatt attcggtggt ggaacaggtc cagcagacgg
    22861 atcaaacgct gttacagcaa caccaggacc attcaacatc aagagaatgt tagaagcagc
    22921 tgaacattta ccagtaaaca taggtatatt agctaaagct ggagcacacg atgatgcacc
    22981 aggagtagaa caaattgcag ctggagcagc tggattcaag gttcacgaag actggggtgc
    23041 aacaagagga tgtatcgata aggctttaga aatggctgat aagtatgata tacaagtatc
    23101 aatccacaca gatacattaa atgaatatgg attcttagaa gatacaatag atgctatagc
    23161 aggaagatgt atccacacat tccatacaga aggagcaggt ggtggacacg cacctgacat
    23221 cataaaggct gctcaataca acaacgtatt accagcttca acaagtccaa cattaccata
    23281 cacacataac acaatagcag aacacttaga tatgttaatg gtatgtcacc acttagatcc
    23341 aaaaatacca gaagacgtag catttgctga ttcaagaatc agacaccaaa caatcgaagc
    23401 tgaagacgta ttacacgata tgggtgtaat aagtatgaca agttcagatg ctatcgctat
    23461 gggaagaatc ggagaagttg ttacaagaac atggcaagtt gctcaccaca tgaagaacct
    23521 aagaggacct ttagaaggag acagcgaata taacgataac aacagaatca agagatatgt
    23581 tgctaagtac acaatcaacc cagctatcgc tcaaggtgta ggagaataca tcggatcagt
    23641 tgaagttggt aagtatgctg acttagtatt atggacacca caattcttcg gagttaagcc
    23701 agaaatgata atcaagaagg gtcttatttc tatggctgtt tcaggtgatc caaatgcttc
    23761 aatcccaaca attcaaccaa gaatcttaag aaagatgtac tatgcagaag gaaaaggaat
    23821 tgctcaatca tgtataacat tcgtttcaaa acttgcatgg gaaaacggaa tcaaggaaga
    23881 attaggtctt gaaagagaag tattaccagt taagggaatt agaaacctta ctaagaagga
    23941 catgaaactt aacgatgcta ctcctaagat agaagtagat ccacaaacat acatcgttag
    24001 tgttgacgga gaaccaatag tagctgaacc tgctacagaa cttccaatga cacaaaagta
    24061 cttcttattc taatagataa tctatctggc atagttttgt ataaaactat gccagatgtt
    24121 tataataaag ataattgatg taggaggtat tttactatga tattaaataa aattttagga
    24181 aatataaatg atgatattga tactcaagga ttacatgttg aaaaactata cttaagaagt
    24241 gatgaacttt taaagagaat caatagagtt gtttcagatc atggtcatga atatggtatt
    24301 tcaatagata aaggtgaagt attaaaggat ggagatatcc tatacaaaga tgaaaagaac
    24361 atggttgttg ttagtgttaa atcagatgac gtactaataa ttaagccaga aactataaca
    24421 gaaatgggaa gaattgcaca taatttagga aatagacatt taccagctca atttagagac
    24481 ggtatgatga ttttagaata tgataaacta gttgaagatt tattaaaaca agaagctata
    24541 aaatattcaa gagagcatgt tacgcttgaa aaggcgttta ggcatgtcga gttcggtcat
    24601 aaacatgtat aataatgatg ttaatatatt agaaatttta aatatgatgc aattatgtga
    24661 ttctaacttc ccagtgggat cattcaacca ttcatatgga atggaaaact atctaagaac
    24721 tgga
//
