LOCUS       c00003_NZ_SLZZ..       13197 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SLZZ01000003.1 Muricomes intestini strain DSM 29489
            Ga0244712_103, whole genome shotgun sequence.
ACCESSION   NZ_SLZZ01000003
VERSION     NZ_SLZZ01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:39:05
            Original ID  :: NZ_SLZZ01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13197
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..732)
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MITITGKSVFGGVSIGRLSFYKRKQRVIKRTHVDAVEAECARFQE
                     AKTTAAGQLKELYEKALADVGEANAMIFEIHQMMLEDLDYIESVENIIRTQEVNAEFAV
                     AATADNFAQMFTAMDDAYMQGRAADVKDVSERVLNILCGVDEGIKQTEEPSIIAADDLA
                     PSETVQLDKSKVLGFATMYGSANSHTAILARTMNIPAIIGLGEELSDKLDGQMAVIDGF
                     TGSLYIDPDEETLALMQEKRRE"
     protocluster    1..13197
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1073:3197]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1074..3197
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13197
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13197
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             complement(757..1014)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MMEFKYTITDSEGIHARPAGMLVKQAAGYKSDIKITKGEKSADAK
                     RIFGVMGLGTKAGEEITVTADGEDEETAVSELEVFFKENL"
     CDS             complement(1074..2252)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="Thiolase_N (E-value: 1.9e-94, bitscore:
                     309.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 1e-40, bitscore:
                     131.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVVVVSGVRLPVGSFGGSLKDVSAIDMGAMVVKEAVNRAEIQP
                     SDVDEVIIGQVGEVAENGFVARAVSLKAGMPKETTAYSVNRQCGSSLQSIADAVLEIQT
                     GQADVVVAGGVENISQLPYYVKDARWGARMGHKTFEDGVIDILTWPLDGNHNGVTAENV
                     ATKYHVSREDQDQFALQSHQRACAAIKAGKFKDEILPVELKDRKGNVTVFDTDEGPRDG
                     QTIEKLAKLRPCFVKGGTVTAGNSSSLNDGAAAVVIMAREKAEALGVIPKLKIEGYAVA
                     GFDAELMGYSPKFSSEKLAAKLGLNLKKIDMFEINEAFASQAYAVSRDLGLDPEKVNIY
                     GGGISIGHPIGATGTVLTVKVLYELMRSEKKDAMISMCIGGGQGISMYFTKC"
     CDS             complement(2355..3197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="HCDH (E-value: 1.9e-38, bitscore: 124.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 2.6e-61, bitscore: 200.1,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAVIGAGLMGSGIAQTCAQAGYEVKNIDVFEPAIEKAKVNIEK
                     LFAKKVAKGSMTEAQKNEIFERMTYSSNMEDVRGAGIIIEAVPEKIELKKSVFKQLDKA
                     ADPETIIVSNTSGLSISEMAAATMRPHKVMGVHFFYPAPVMKLAELIRGIATDDDTYSK
                     VRGFVISIKKTVVDAPEYPGFIVNRILVPMQNEAAFMVMEGCKPEDVDNAMKLGANHPM
                     GPLELTDFVGIDVMLATMTGLYNGFHDSKYRPCPLLETMVKAGHLGRKTGQGFYKYDK"
     CDS             complement(3273..4862)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_trans_2_CAF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="CoA_trans_2_CAF (E-value: 1.5e-83,
                     bitscore: 273.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKANFISAKEAASRVKDGSTICPVAMTLVSASESILKELETSFV
                     KTGHPFGLTLLHSCGQSDRKDGIQHLAHEGMVKRIIGSHWGLQPRWMEMIANSKVEAYC
                     LPQGQIAQLYRSMACGLPGKMSKVGLGTFIDPRVEGGKMNERTKPLPDIVDIISYNNQE
                     YMFYKEVPIDVCLIRGTLCDEMGNLTTTEEAMKLEVLPAVLAAKRYGGRVIAQVKQVIQ
                     TGSINPKDVTVPGVFIDDVVVCENPMEDHRQTSSWYFDPSYCGQVRVPQGNIQPAPFNE
                     RKFIARRGTLELYHGAVVNLGTGIPNDMVGKICNEEGVSDDIMITVESGIYGGVQAGGI
                     DFGIGQNLYAMIGHHEQMDYYNGAGVDITYMGLGELGEDGSVNSTKMGSRCTGAGGFID
                     ITQNAKKIVFLGTFTAGGAKYEFADGKLTILQEGKICKMVKRVAQLSFNGPMAREKGQE
                     VLIVTERAVFRLCKEGVELMEIAPGINLQTQVLDQMDFQPIVSPKLKLMDKKLFIRDGA
                     FGLELKEKPERK"
     CDS             complement(4865..6478)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 267.2; E-value:
                     6.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-81, bitscore:
                     267.2, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 5.3e-17, bitscore:
                     56.2, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEGKDVWNPWFQTDMEDIKIGDRTVYTFSKMKKSFYEMLEDTAE
                     RYPDKPGLCDNWNRSYTYREFLHMVDSLAAYLKNVLHVKKKSHVGLLLNNGIEFATAFY
                     AVCKLGAVAVPLPTKYREPEIQSLTDKADLYCVLVSEDYGSLIRDYEDAGIIVLCTRDE
                     ENGYGFCYLNLPGGGTELSAPGCGELEDEMILMFTSGTTSESKGVILKNYNINHAVMIY
                     QRLLELGPEDKTIIPVPIYHITGLVALLGLFVYMGGTVYLYKRYDARRILEGINNHGIT
                     FMHGSPTVFGLLLDYQKEFPELKSVRKLACGSSYIPVETMKKLHRWMPGMEFQNVYGMT
                     ETSSPGTIFPYDAAISIYPKSQGKPIPGMHLKIVDDGREVADGIVGSIYLKGANICEYY
                     YNIDSPLITPDGWLDTGDMGYINEDSYVFIVDRKKDMINRGGEKIWCTDVENELLSLEG
                     IKDTAVVGIPNGVYGEVAAAVVVLEKGSRLTEEEIKIGLKNRLAKFKIPEKVIFVDEVP
                     KTPGLKTDKNYIRTLFEKGN"
     CDS             complement(6504..7388)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MYVSMKDMLWHAHKNQYAVMAINCVNMEQAKAIIQSAEEEKSAVI
                     INISPRQMKAHGHADILAPMIKGMAKKVSVPVAFNLDHGADFEDITYAMQCGFSSVMID
                     SSSYEFEENVRRTQMIASLAHGMGLSCEAELGHVGAAKEADNEKEDLYTNPQQAKEFVE
                     RTGCDCLAVAIGTAHGSYPKGFIPRLDFERLKLLKETLQIPLVLHGGSGAGEKNIKKAV
                     ACGINKINVCTDLFKHARIATARALEENPEIDYMDLCIEAQNAMKDFIKNYMRMIGSSR
                     RYDFEKHQGPEFD"
     CDS             complement(7414..8499)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="PTS_EIIC (E-value: 5e-12, bitscore: 38.9,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEIKRKTKKKSQGAFLRDSIMTGISYMIPVIVGAGVIQAIAKAM
                     GGYDIANHMEEIDTLAKAIMLLGQNMMNFVVPVIAAFIAYAMADKPGLAPGFVMGALAG
                     AINTGFVGGLVGGIMVGYFILALKKIKVPKSLQGVMPILIIPVVTTLVCGLLMYYVVGV
                     PIRLFMEWVTLGLTSLSGGSKFLLGAVIGAMICFDQGGPINKTAALFVNGLNADGFLIP
                     TAAKMCAGMTAPLGIGLACFIGGKKKFTHSEREQAKSLFILSCCYVQEGVIPFLMKDPV
                     RVVISTMTGGAITGGLCMISALESPAVHGGAFVIAMTSNPLMFVGYWLLGGCITGVLYA
                     ILRRPLPEGYVESEDDSVSII"
     CDS             complement(8501..8809)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MYILGVTSCPVGIAHTYMAASNLEKCAKKKGLEVKIETQGATGVE
                     NEITKEDVKRADAVIIASDVRIKNGSRFDDLPTLTVGVSEAIKDADGIINELLEALK"
     CDS             complement(8811..9272)
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MNIAEMIDEKLVNFDFEAGTKDDVLKGLGKMMYDAGKVSDLKQYI
                     DGLYERETEFSTGVGNGVAIPHCKSGCVREAAFTLVKLKNPVEWETLDGRPVDYVIMLA
                     APNTSDNVHLKMLSRLAANLVDDDFREALKSASSVKEIKDLFSSKKEEE"
     CDS             complement(9302..11248)
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MFLPREKKILNLLLKSEKKLTTSQVAAELKVSPRTIKTDVKKINT
                     ELERHSCFIRTRQGVGLWLDFDENGKRYLKTAIYEESDLYMSAEARKYYIAVALLNSKE
                     YTSMESLAGRFYVSKGTVVNDVNELEPFWRKFDIAFSKKVKYGIKAEGMESQTRLALID
                     ALKKVAGAPGKAAAEKIQPMFENVDLNQLKDIIKGTEKRFHFILTDISFDEFLIQLAVM
                     LQRLEMGHGMDDKAKDVALHIERKEWFISQFLKEQIAEYTRIEVPEKEMEYLICCLRGM
                     RFQVPMVKEKNLKKMRSRAPEMFDYMMKILEEIDEKYHLNLEEDDELSYAMFDHLECMV
                     HRIQSKMYLTNPILESVKKEMFYEYEIASYLIAKFSAKYEVETTEDEIGYITFHIGASI
                     ERMTQKKKKSFTVTIVCMTGIGTSQFISMKLKRLFPNIEVSKIISANMAEGLDERGQDF
                     VISTIPLYLEKIEVIQVSPVLNEEDVRRIQKHIHKQENKQTEEKFTYFYLKNLLHEEIT
                     ILNCDLKSKEEVMELLGKRMIREGYVDAGYVDSIFERERLSDTCIGSLIAIPHAFDGHI
                     LRQGIGLLTLKKPVAWGNEKVQIVFMLALNTKAENHFQGIFGEMLDLTKNSKDVAQMLK
                     ARKFNEIEIFKRG"
     CDS             11618..12799
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     309; E-value: 1.3e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_12"
                     /sec_met_domain="Fe-ADH (E-value: 3.6e-94, bitscore: 309.0,
                     seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFEFYNPTKVIFGKGVEAEAGKEIKALGGHKVLVHYGGTFLQE
                     NGTLDRVHKGLEDAGLDYIDLGGVVPNPRLGLVKEGIQLCKDEGVDFLLPIGGGSAIDS
                     AKGIGYGLVNDFSLEDLLLGKVTTDKIAPIGCISTIAATGSETSNSMVITIEDGMLKRS
                     YNHDCARPKFAIMNPELTYTLPVYQTASGGSDIMMHTMERYFTNTKDVDLIDRMAEGLL
                     VSVREAVKVAVKEPQNYEARATLMWAGSLSHNGLTGTGRVSDFASHKIEHELGGMFDVA
                     HGAGLCAIWGSWARYVLKTNPTRFAQFAVNVFNVPENFYNMEVTALKGIEAWEDWCRKI
                     GMPTNLKELGVEPTDAQIEEMARKCVATGGGHVGFFQTLYKDDVIKIYEMARK"
ORIGIN
        1 ctccctgcgc ttttcctgca tcagggcaag agtctcctca tccgggtcta tgtacagact
       61 gccggtaaaa ccgtcaatca cagccatctg tccgtcaagc ttgtcactta attcctcacc
      121 cagcccgata atagccggaa tgttcatcgt tcttgccaga attgccgtat gagaattggc
      181 agacccatac atggtagcaa aaccaaggac cttgcttttg tccagctgta cagtctcact
      241 gggcgccaga tcatcggctg caataatact gggctcctcc gtctgcttta tcccctcatc
      301 tactccgcag agaatattca gaacacgctc cgatacatcc ttcacatctg cagcacgtcc
      361 ctgcatgtat gcatcatcca tagcagtaaa catctgcgca aaattgtccg ccgttgccgc
      421 caccgcgaat tccgcgttca cttcctgggt acggatgata ttttcaacag attcaatata
      481 atccagatcc tctagcatca tctggtggat ttcaaaaatc attgcattcg cttcacccac
      541 atctgccagg gccttttcat aaagctcctt cagctgcccg gcggctgttg tcttagcttc
      601 ctgaaaccgg gcgcattcag cctccacagc atcgacatgt gtgcgcttaa tcactctctg
      661 cttcctttta taaaaagaaa gccttccgat ggaaacaccg ccaaatacac ttttacctgt
      721 tattgtaatc atactatttc ctctgacatt cctgaattat aagttttctt taaaaaatac
      781 ttccagctct gagacggcag tttcttcatc ttctccatct gcagtcacag tgatttcttc
      841 acctgcttta gtacccagtc ccataacacc gaaaattctc tttgcatcag cactcttttc
      901 accctttgta atcttgatat cggacttata gcctgcagcc tgctttacca acattcccgc
      961 cggtctcgca tggattccct cagaatctgt aatggtatac ttaaactcca tcatggtaaa
     1021 atcctcctct tattttcctt ttcttaaccc ttgtatacgg aaactcaagg cttttagcat
     1081 ttggtaaaat acatagatat gccttgtccg ccaccgatac acatactgat catggcatcc
     1141 tttttctcag agcgcatcag ttcatacagt acttttactg tcagcactgt acctgtggcg
     1201 ccgatgggat gtccgatgga gatgcctcct ccataaatat ttactttctc cggatccagc
     1261 cccaagtccc ggctcacagc ataagcctgg cttgcaaatg cctcattgat ctcaaacatg
     1321 tcgattttct tcaggttaag tcccaatttc gcagccagtt tttcactgga gaatttaggc
     1381 gaatagccca taagctccgc atcaaaccca gccactgcat agccttcgat tttgagtttc
     1441 ggtataactc ccagtgcctc ggccttctcc cttgccataa taaccactgc agctgcaccg
     1501 tcatttaaac tggaagaatt tcctgccgtg acagttcctc cctttacaaa gcaaggacgc
     1561 agttttgcaa gcttctcaat tgtctgtcca tctcttgggc cctcatctgt atcaaagacc
     1621 gttacatttc cctttctgtc tttaagctcc accgggagaa tctcatcctt gaacttgcca
     1681 gccttaatag cggcacatgc ccgctgatgg ctctgcagtg caaattgatc ctgatcttct
     1741 ctagatacat gatactttgt tgctacattt tctgcagtca caccattatg attcccatcc
     1801 agcggccatg taagaatatc aattacaccg tcctcaaacg tcttatgtcc cattctggct
     1861 ccccagcgtg catccttcac ataataaggc agctgtgaga tattttccac accaccggcc
     1921 acaactacat cggcctgtcc tgtctggatc tccagcactg catctgcgat ggactgcagg
     1981 cttgacccac actgacggtt tacagaatac gccgttgtct ctttgggcat acctgctttc
     2041 aaactgacag cccttgccac gaatccattt tccgcaacct cacctacctg tcctatgata
     2101 acctcatcta catcagaagg ctggatttcc gcccggttca ccgcttcctt tacaaccatt
     2161 gcacccatat caatcgccga aacatccttc agactgcctc caaaactgcc taccggaagt
     2221 ctcactccgc taacaactac tacatctctc atttcgttct cctttcaaag tatccgcaaa
     2281 ggggtcagtc ccttttgtcc tccatattca gaatattctg acttccggct gcaaaaggga
     2341 ctgacccctt tgagctattt gtcgtattta tagaatccct gtcctgtctt gcgtcctaag
     2401 tggcctgctt ttaccattgt ttcaagcaga gggcacggtc tgtatttgct gtcatgaaag
     2461 ccattgtaaa gtccggtcat tgtggccagc attacatcga tccccacaaa atctgtcagc
     2521 tccagcggcc ccattgggtg gtttgctccc agcttcatgg cattgtccac gtcttccggt
     2581 ttgcatccct ccatgaccat gaatgcggct tcgttctgca taggaaccag aatacggttt
     2641 acgatgaagc cggggtattc cggtgcatct actacggttt ttttgatact gatgacaaat
     2701 cccctcactt tgctgtaagt atcgtcatcg gttgcaatgc cgcggattag ttctgccagc
     2761 ttcatcacag gtgcagggta gaagaaatgt acccccatta ctttatgagg ccgcatggta
     2821 gctgccgcca tctcggagat gcttaatccg gaggtattgg agacgatgat tgtctccgga
     2881 tctgcagctt tgtccagctg cttgaataca gattttttta attctatttt ttccggcact
     2941 gcttctataa ttattcctgc acctctgaca tcctccatgt tgctgctata tgtcattctt
     3001 tcaaaaattt cattcttttg tgcctctgtc atactgcctt ttgcaacttt ttttgcaaat
     3061 aatttttcaa tattcacctt tgctttttca atggcaggct cgaatacatc gatgttcttt
     3121 acctcatatc ccgcctgcgc acaagtctgg gcaataccac ttcccattag tcctgctccg
     3181 attactgcta ctttcattgt caaacacctc tttctatgaa atatataaaa tctacatgct
     3241 gccaaatata cattgcctgt aatccgccct tgctactttc tctctggttt ttccttcaat
     3301 tccaaaccaa atgccccgtc ccggataaat aattttttat ccatcagttt cagtttagga
     3361 cttacaattg gctgaaagtc catctgatcc agcacctgtg tctgcaaatt tattccggga
     3421 gcaatctcca ttaactctac tccttcttta caaagcctga ataccgcccg ttctgtgacg
     3481 attagaacct cctgtccctt ttctctggcc attggtccgt taaaggacag ctgtgccacc
     3541 cgcttcacca ttttacatat ttttccttcc tgtaaaatgg tcagcttccc gtcagcaaac
     3601 tcatatttag ccccgccggc tgtaaaggtc cccagaaata ctatcttttt agcgttctgg
     3661 gtgatatcaa tgaacccgcc ggcaccggtg caccgggagc ccattttagt ggagtttaca
     3721 ctgccgtcct cccccagctc gccaagcccc atgtatgtaa tatccacacc ggcgccgtta
     3781 taataatcca tctgctcatg atgcccgatc atggcataca ggttctgtcc gattccaaag
     3841 tctatgcccc ccgcctgtac tccgccgtat attccggatt ccactgtaat cataatgtca
     3901 tccgacacac cttcttcatt acagattttt cctaccatat cattggggat tcctgtacca
     3961 aggttcacca ctgctccatg atacagctcc aaagtcccac gccttgcaat aaactttctc
     4021 tcattaaatg gcgcaggctg gatatttccc tgagggaccc tgacctggcc gcagtaggat
     4081 gggtcgaaat accaggagga ggtctgccgg tgatcttcca ttggattctc gcacacaaca
     4141 acatcatcaa taaatacccc cgggacagtt acatccttgg gattgatact ccctgtctga
     4201 atgacctgct ttacctgggc aatgactcta ccgccgtaac gcttggccgc cagtaccgcc
     4261 ggcagtactt ccagcttcat tgcttcctcc gtcgttgtca gatttcccat ctcgtcacag
     4321 agagtcccac ggatcagaca gacatcaatg ggaacttctt tataaaacat atactcttgg
     4381 ttgttatagg aaataatatc tacaatatcc ggcaggggct ttgtgcgctc gttcatcttg
     4441 ccgccttcca cccggggatc gataaatgtt cccagtccca ccttggacat ttttcccggc
     4501 agaccacagg ccatgcttct gtacagctgg gcaatctgcc cctgtggcag gcagtatgcc
     4561 tccaccttac tgttcgcaat catctccatc catctgggct gaagccccca gtgagaaccg
     4621 atgatccgct tcaccatccc ctcgtgagca agatgttgta taccgtcttt tcggtcgctc
     4681 tgtccacagg aatgaagcaa agtcagtccg aacggatgcc ctgtcttcac aaaacttgtt
     4741 tccaattctt ttaaaattga ctcacttgca ctgacaaggg tcatggcgac cgggcaaatg
     4801 gtgcttccat cctttaccct ggaagcagct tccttcgcac tgataaaatt tgctttcagc
     4861 ataactagtt tcctttctca aataatgtcc tgatgtagtt cttatctgtc ttgagcccag
     4921 gtgttttcgg cacctcatcc acaaaaatca ccttctccgg aattttaaac tttgccagcc
     4981 ggttcttcag cccgatttta atctcttctt ccgtcagcct gctgcctttt tccaaaacaa
     5041 ccacagcagc ggcaacttcc ccgtatactc cattgggaat cccgaccaca gctgtatcct
     5101 taatcccctc caaagagagc agctcatttt ccacatccgt acaccaaatc ttctctcccc
     5161 cgcggttaat catatctttt tttcggtcta cgataaacac ataggaatct tcattaatat
     5221 atcccatatc tccggtgtca agccatccat ccggcgtaat caggggcgag tcgatattgt
     5281 aatagtactc acagatatta gcgcccttca ggtatatgct cccaacaatc ccatcggcca
     5341 cttctcttcc atcatccacg attttcagat gcattcccgg aatcggcttt ccctgcgact
     5401 tgggataaat actgattgcc gcgtcatagg gaaaaattgt ccccggtgaa gaagtctccg
     5461 tcatcccata tacattttga aactccattc cgggcatcca cctgtgaagc tttttcattg
     5521 tttccaccgg tatatagctg ctgccgcagg caagcttccg cacgcttttc agttcaggga
     5581 attctttctg gtaatccaaa agtaacccaa ataccgtggg ggaaccatgc ataaaggtta
     5641 ttccatgatt atttataccc tccagaatcc ttctggcatc ataccgctta tacagataaa
     5701 ccgtgcctcc catatagaca aataacccca acagcgccac aagccctgta atatgataaa
     5761 tgggaacggg tatgattgtt ttatcctccg gtcccagttc taaaagtctc tgatatatca
     5821 tcacagcgtg attgatatta tagtttttca aaataactcc cttgctttcc gaagtcgtcc
     5881 ccgaagtaaa catgagaatc atttcatctt ccaattcacc acaccctggg gcggacaatt
     5941 cagtcccgcc ccccggcaga ttcagataac aaaacccata tccgttttct tcatcccgtg
     6001 tgcataaaac aattatccca gcatcctcat aatcccgtat caagctcccg tagtcctcac
     6061 tgacaagaac acagtacaaa tctgccttat ctgtcaatga ctggatctcc ggttccctgt
     6121 atttcgtggg gagcggcact gcaaccgccc ccagcttaca tactgcataa aaggctgtgg
     6181 caaactcaat tccattattc agcagcaggc ccacatgact ttttttctta acatgcagca
     6241 catttttcag atatgctgcc agactatcca ccatatgtaa aaactcccga taagtgtagc
     6301 ttctgttcca attgtcacac aatcctggtt tatcgggata cctttcagcc gtatcttcca
     6361 gcatctcata aaaacttttt ttcatctttg aaaatgtata gacagtccgg tctcctattt
     6421 ttatatcttc catatctgtc tgaaaccatg gattccatac atctttccct tctaacatga
     6481 cggcacctca ttttccctgt gtactaatca aactccggac cctgatgctt ttcaaaatca
     6541 taacgtctgc ttgaaccaat cattctcatg taattcttaa tgaagtcctt catagcattc
     6601 tgtgcctcaa tgcataaatc catatagtcg atttccggat tttcttccag agctcttgct
     6661 gttgctattc ttgcatgttt aaataagtca gtgcatacat taatcttgtt aattccgcag
     6721 gcaactgcct tttttatatt tttttcacct gctccggagc ctccgtgaag tacaagcggt
     6781 atctgcagtg tttccttcag taattttaat ctttcaaaat ccaacctggg aataaatcct
     6841 ttcggatagc tcccatgtgc tgttcctatg gccactgcca gacagtcaca tccggtcctc
     6901 tccacaaact cttttgcctg ctgaggattc gtgtataagt cttccttttc attatccgct
     6961 tcctttgccg cacctacgtg accaagttca gcctcacagg aaagtcccat accatgggcc
     7021 agtgatgcaa tcatttgcgt tcttcttaca ttctcctcaa actcgtaact agaagagtcg
     7081 atcatgacac tggaaaaccc acattgcatt gcatatgtaa tatcctcaaa atcagcacca
     7141 tgatctagat tgaaggccac cggaacagac accttttttg ccattccttt tatcatcggc
     7201 gccaagatat ctgcgtgccc gtgtgctttc atctgacgag gagaaatatt aataataact
     7261 gcagatttct cctcctcggc agactggata attgcttttg cctgttccat gtttacacag
     7321 ttaattgcca taactgcata ttgatttttg tgtgcatgcc agagcatgtc tttcattgat
     7381 acatacatat ttttctccta ttccaacaat tcactaaata atagaaacag aatcgtcttc
     7441 actttcaaca tatccctccg gaagtggtct cctcaggatt gcatacaata cgcctgtgat
     7501 gcatccgccc agcagccagt atccgacaaa catcagtgga ttggatgtca ttgcgatgac
     7561 aaatgcacca ccgtggacag ccggggactc caatgcagaa atcatacaaa gccctccggt
     7621 tatggcacct cccgtcatag tggaaatcac gacgcggacc ggatctttca tcagaaacgg
     7681 gataacacct tcttgaacat agcagcagga tagaataaac aaagactttg cctgttctct
     7741 ttcactgtgt gtaaatttct ttttcccgcc gataaagcat gcaaggccga ttcccagtgg
     7801 ggccgtcata ccggcacaca tctttgcggc tgtgggtatt aagaacccat cagcattcag
     7861 cccatttaca aacagagctg ctgtcttatt aatcgggccc ccctgatcaa agcaaatcat
     7921 agctccgatc actgcaccta agaggaactt tgaaccacca cttaaggaag tcagtccaag
     7981 cgttacccac tccataaaca gccggatcgg cacacctaca acatagtaca tcagcaagcc
     8041 gcagaccagt gtagtaacga caggtataat caaaatcggc ataacgccct gtaatgactt
     8101 gggtacttta attttcttca gtgcaagaat aaagtatcca accatgatac cgcctacaag
     8161 gccccccaca aatccagtat taatcgcacc tgcaagggca cccattacaa acccaggagc
     8221 aagcccgggc ttgtccgcca tggcatatgc gataaatgct gcgataaccg gtactacaaa
     8281 gttcatcatg ttctgaccaa gaagcataat tgcttttgcc agtgtgtcaa tctcttccat
     8341 atggtttgcg atatcatatc cgcccattgc ttttgcaatt gcctgaataa caccggcgcc
     8401 tacaataaca ggaatcatat aagatatacc tgtcataata gaatctctca gaaatgctcc
     8461 ctggcttttc tttttcgttt ttctctttat ctccgccatt ttatttcaat gcctccaaca
     8521 attcgttaat tattccgtct gcatccttga ttgcctcact gactcctact gtcaatgtag
     8581 gcagatcatc aaatctacta ccgttcttga ttctcacatc gctggcaatg attacagcat
     8641 ctgccctctt aacatcctct tttgttattt cattttccac gcctgtagct ccctgagttt
     8701 cgatcttcac ctccaggccc tttttcttag cacatttttc cagattagat gctgccatat
     8761 aggtatgtgc gattcccacc ggacagcttg ttactcccag aatatacatc ttattcctcc
     8821 tccttttttg atgaaaataa atctttgatt tccttcacag atgacgcact tttaagtgcc
     8881 tctcgaaaat catcgtccac cagatttgcc gccagtctag aaagcatttt taaatgtaca
     8941 ttatctgatg tgtttggggc ggcaagcata atcacataat caaccggacg tccatccagt
     9001 gtttcccatt ccaccggatt ctttagtttt accaatgtga atgctgcctc tctgacgcag
     9061 ccggatttgc aatggggaat tgcaacaccg ttccctaccc ctgttgagaa ctcagtttcc
     9121 ctttcataaa gtccatctat atattgcttc aggtcactta ctttacctgc gtcatacatc
     9181 atttttccaa gaccctttaa tacatcatct ttggtcccag cctcaaaatc aaaattcacc
     9241 agtttctcat caatcatttc tgcaatattc atatacaact aaattccttt ctttttaagc
     9301 gctatcccct cttaaaaatc tctatctcat taaattttct ggcttttaac atctgtgcca
     9361 catcttttga attctttgtc agatccagca tttctccaaa aattccctgg aaatgatttt
     9421 cagcttttgt attcagcgca agcataaata caatctgtac tttttcattc ccccaggcta
     9481 caggcttctt taaggtcaaa agtccaattc cctgcctcag gatatgtccg tcaaacgcat
     9541 gaggtatggc aatcagactg cctatacaag tgtcggaaag cctttccctt tcaaatatgg
     9601 aatctacata tccagcatcc acgtaccctt cccttatcat ccttttcccc agcaattcca
     9661 taacttcttc ctttgatttc aagtcgcagt ttaatattgt aatctcttca tgcaacaaat
     9721 tctttagata aaagtaggta aatttttctt ccgtctgctt attttcctgt ttatggatat
     9781 gtttttgaat acgccttacg tcttcttcat tgagtaccgg ggatacctgt attacttcaa
     9841 tcttctccaa atagagggga atcgtggaaa tcacaaaatc ctgccccctc tcatccagac
     9901 cctctgccat attcgcagag ataatttttg aaacctcaat attggggaaa agtcttttca
     9961 gtttcattga tataaactgt gacgtaccaa tacctgtcat acatacaatt gttacagtaa
    10021 aacttttctt tttcttctgg gtcatgcgtt ctatggaagc cccaatatgg aaggtgatat
    10081 atccgatttc gtcttctgtt gtctcaacct catatttagc actgaacttt gcaatgagat
    10141 aagaagcaat ttcatactca taaaacatct ctttctttac cgactccaga attggatttg
    10201 tcagatacat cttgctctgg atccggtgaa ccatacactc cagatgatca aacatggcat
    10261 aggacagttc gtcatcttct tccagattca gatgatattt ctcatctatt tcctccaata
    10321 tcttcatcat atagtcaaac atttccggtg cccggctgcg catctttttc aggttttttt
    10381 ccttgaccat aggaacctga aagcgcatcc ctctgagaca gcaaatcaaa tactccattt
    10441 ctttttcagg cacttctatc ctggtatact ctgcaatctg ttccttcaaa aactggctga
    10501 tgaaccattc ctttctctct atatgaaggg caacatcttt agccttgtca tccatgccat
    10561 ggcccatttc cagacgctgc agcatgacag caagctgtat aagaaactca tcgaaagata
    10621 tatccgtcaa aataaagtgg aatctttttt ctgttccctt tataatgtct tttaactgat
    10681 ttagatctac attttcaaac attggctgta tcttttcagc agcagccttt cctggagctc
    10741 ctgctacttt ttttagagca tcaatcagag caagcctcgt ctgtgattcc attccttctg
    10801 ccttgattcc atattttact ttttttgaaa acgcaatatc gaacttcctc caaaacggct
    10861 ccagttcatt gacatcattc acaacagtcc ccttacttac ataaaacctg ccagccaggg
    10921 actccatcga agtgtattcc ttgctattta aaagggccac cgcaatataa tactttctgg
    10981 cctccgccga catatataaa tctgactctt cgtaaatagc cgttttcaga taacgtttcc
    11041 cattttcatc gaaatccagc cagaggccca cgccctgcct ggttctgata aaacaggagt
    11101 gtctttctaa ctctgtattg atttttttaa catctgtttt gattgtcctg ggactgacct
    11161 ttaactccgc agcaacctga gatgtggtta attttttctc actctttaaa agtaaattca
    11221 atattttctt ttctcttggt aaaaacattt gacccacctt ccccgctgtt cgagcatatt
    11281 atatctgccc ggcagctcgt tttacaaatc atataatttc acctgcaaac aaaaacttgg
    11341 tgcaactagt attaaatata tcacactttt tttaatttcc tatgatacct tgtctatttt
    11401 gcatgtttta taagaccttt tgtcaaaaaa tcatgccctt ttttgtgcat actgttctgt
    11461 ccacaaaaat ttcacttttc ttatcatatt gtttcactta cttagtgcaa tttttcaatt
    11521 attcattttc tccaaaaata tttataatga gacacagtaa aaggaaagga tttattcgca
    11581 gcattttata tactgcacta tttaaggagg tttttacatg attaattttg aattttacaa
    11641 tcctactaaa gtcatttttg ggaaaggtgt ggaagcagaa gccggaaagg aaataaaggc
    11701 actgggcggt cacaaggtcc tggttcatta tggcggtaca tttcttcagg aaaatggaac
    11761 tctggatcga gttcataaag gtcttgagga tgccggactc gattatattg atctgggagg
    11821 agtagttcca aatccacggc ttggtcttgt aaaagaaggg atacagcttt gcaaagacga
    11881 aggagttgat tttcttcttc caatcggagg aggaagcgcc attgactctg caaagggcat
    11941 tgggtatgga cttgtcaacg atttttcact ggaagatttg ttgctcggca aggttacaac
    12001 tgacaaaatt gctcccatcg gatgcatatc tactatcgca gccaccggat ctgaaacaag
    12061 taattccatg gttattacga ttgaagacgg tatgctgaaa cggtcctata accatgactg
    12121 tgcgcgtccg aaatttgcta ttatgaatcc agagcttacc tatacacttc cagtttatca
    12181 gacagccagc ggcggctctg atattatgat gcatacaatg gagcggtatt ttaccaatac
    12241 caaggatgtg gacttaattg accgtatggc agaaggtctc cttgtctctg tccgcgaagc
    12301 tgtaaaagtt gccgtaaaag agccgcaaaa ttatgaggcc agggctactt taatgtgggc
    12361 aggcagcctt tcacataacg gcttgaccgg aacagggcgt gtatcagact ttgcttccca
    12421 taagattgaa catgagctgg gcggaatgtt tgatgtggct catggtgcgg gattgtgcgc
    12481 catatgggga agctgggcaa gatatgtctt gaaaaccaac cctacaagat ttgcacagtt
    12541 tgctgtcaat gtatttaatg taccggaaaa cttctacaat atggaggtaa ccgcattgaa
    12601 gggtatcgaa gcatgggaag actggtgccg caaaattggc atgccgacaa acttaaagga
    12661 gcttggtgtg gaacctacag atgcgcaaat tgaagaaatg gcaagaaaat gcgtggccac
    12721 cggcggcgga cacgtaggat ttttccagac attatataaa gatgatgtga taaagattta
    12781 tgaaatggca cgaaagtaaa ataaagccat ttagctattg ttaaatctgt gctctaatat
    12841 tataatcgat ttttcgtata tttcccctga ttttccacat actaattgta atttagccgg
    12901 tgaaggagaa tgagtatgga taagattgaa aaagtaaagc aggaaaagca atatcaggat
    12961 tatgtaaagc gtaaaactcc tgttcataat gtttattcaa atatggggaa agcgtttatc
    13021 acaggcggta taatctgtac cttgggacaa tttatttata attattgtga acttcagggc
    13081 atgtcaaaag atgaatgcag cggctggacc tctctcctct taatactaat cagtattatc
    13141 cttacgggga tgaatatata ccccaagata gcaaaatggg gaggggcggg cgctctg
//
