LOCUS       c00046_NZ_WAJS..       12284 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_WAJS01000046.1 Adlercreutzia muris strain DSM 29508
            DSM29508T_contig_046, whole genome shotgun sequence.
ACCESSION   NZ_WAJS01000046
VERSION     NZ_WAJS01000046
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:38:36
            Original ID  :: NZ_WAJS01000046.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12284
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12284
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1860:6124]"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1861..6124
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
     cand_cluster    1..12284
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /kind="single"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12284
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /region_number="1"
                     /rules="((DmsC and Molybdopterin and minimum(2, [Fer4_11,
                     Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or (NrfD and
                     Molybdopterin and minimum(2, [Fer4_11, Molybdop_Fe4S4,
                     Molydop_binding]) and not (Nitr_red_bet_C or
                     Nitrate_red_del)))"
                     /tool="gutsmash"
     CDS             161..766
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MEANTLRVDTRTRVTTFYAEETLTADLVPLDVDAVLFWHVWDAKA
                     ACLEVGDFIRAVEMAAQTALRDAIGRAGAAEVAIRREQLDRELKRVLEEKTAPWGVTVL
                     SVEVRDILLPRELQEAMSLEAQAEQRKKARIILMEAEQDIFETLAEMEDLVGGPEAVGR
                     LRTMHLLNESLREGKGTVVIPSAFAEGFNEGVGDLIKG"
     CDS             complement(800..1105)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MPDLLDPITPGELLSEEFLKPLGLSQYRLAKEIGVPAQRIGQIVL
                     GRRTITADTDLRLCRFFGLTDGYWLRAQEAYDLEIARRKLEPELKRIRPFNQAACL"
     CDS             complement(1115..1393)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MIRTFADKSTELLARGQRVQRFVAFERVARRKLRQLEIAGDLQDL
                     RIPPGNHLEKLSGDREGFWSIRINDQYRICFRWTAAGPTDVQITDYH"
     CDS             1861..4284
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="Molybdopterin (E-value: 8.8e-47, bitscore:
                     149.7, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 8.1e-20,
                     bitscore: 60.8, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGARNSTLTRRSFLKTTGSAAAGLACVGAAGAALSGEVLAPARA
                     HAEGEERTAHLCHQFHCLTGCNLKCTIRDDRITLIEPSDLMVDKKHSTICLRGIGEVAH
                     IYAQDRLKVPMKRVGERGEGEFVQISWDEAIQTIADNLKEAQQKYGEGSVFIRKSTEAG
                     IEFDFLAQLIHADSGGNWGLDRGQANGLGPALGPWSYLSNRSHWEFKDAATIIELSHNP
                     LESAMVWSRPLMDAKEAGTYIVTIDPRFTGTAAKSNEWLPVCPGTDAAIIQGMLKAIVD
                     NGWYDEEFMLSRTSCPYLVDRATGKSYRSAEVMAPNPTVVGAEPVGAPFVWDTVTNAPV
                     LYDNATAVPALEGEWTVDGMQLVTEFTLIKEWLDTITLSWAAQTSGIDEQVIVNLADRY
                     ANNGPAIIDIGLGGADKYTNADVLGHSTALLVALTGQYGKKGAGLGSYCGLGSNDPSAT
                     LNYWVLPEEYHYGESPVAMYDMPYQENNIHAALTFGDAFTLEAGAANDMLEWVKSLDFF
                     AIVDLYHSSAVDYADIVLPACTKFECEENVKQLRDSMGHVMLANGMVAPLFESKSDLQI
                     ERLLAAQWGLEDLLPETYEELARFMLDGAAELDPRMEGITYDALLANGGVMALPETGED
                     YLPDGLAEGFLTPSTRIELYYEYLADQGHGLPVYEDANEAYESNPKKEQFPLYFTQGKS
                     RYRIHAYYSANEWFQEDFGPSLNMAPEDAEARGIVTGDDVRVFNDRGSFVATALVNRSL
                     QPGVLFMAETTYTRYYKEGFLQNVTNSARLERGYSMFFGPQIPYNDVLVEVEKA"
     CDS             4293..4910
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 29.6; E-value:
                     2.7e-09)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_5"
                     /sec_met_domain="Fer4_11 (E-value: 2.4e-17, bitscore: 52.8,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-07, bitscore: 21.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRYGMAINQTRCIGCQTCAFACKMQNGVAKDMRWNRVLTEGGGV
                     ADDAQGQYPNLTRTYLPLACQHCENPACLKACPTGATYKDEVGRVEIDYDKCIGCRMCM
                     AACPYNARSFNWAEPAFVPDFAYGDGQVERRERGVAEKCTLCKERTDRGEEPRCVQCCP
                     LDARIFGDLDDPNSEVSKVIVERKARVLLEEQGTRPQVYYFE"
     CDS             4922..6124
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: NrfD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="NrfD (E-value: 7.6e-48, bitscore: 153.4,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKRNKAATAVLIVLACVGVGAWIYQLMGGLAVTGMSNGVSWG
                     AYITMFMFFVGLSAGGLIVASSASVFHIKAFKQVAMPAVILSTVCICLAGMFVLIDLGG
                     IQRVWRVVTGPNPASPLVWDICVITCYLVINILYLHFMRKGAERAVAMVSRFALPCAIL
                     VHSVTAWIFGLQIAKEGWFSAIMAPIFMASAMDSGLALLLIVLSALNASGRFKTPKELI
                     ASLAGLLATCIAVDAYFIFCEVLTMGYPGAAGAETLALMVTGPTAPFFWFEVIGGLLVP
                     FCVLVFAKNRAKTGLVVGASVLVVAGVLCKRVWLLFTSFIGQNVAGAPGVMTADGWAMA
                     GSYAPTLVEVTIIVGVVSVGALGFMALASKLLQPAAEEETVPAATSRTSAPELEFDPQV
                     A"
     CDS             6538..7104
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MEKILDLVRSNNLVQAVLCIAFGLFLMIYPSITIQGIIMLFGVAL
                     ALMGAAGLVSYFRQKSVRYRNTGTLMGAVFYLIIALIAFVFPKVIAGFFSVVLGVVLIL
                     FAIVNVVRALGLRAFGGSIWIAVLVAAVIVGVGGVLIVVNPWGASMTFVLVLGAAFIAN
                     GAVDLFIEWYARDSAKQADLMARPR"
     CDS             7439..7720
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="MSEENSNLAEIQKHREQIDAIDREIVALLNKRAGHSLVIRGLKPG
                     AHMGLYDARREEEIFARVDSYNEGPLYNENLREIYATILKIMKETPSV"
     CDS             7717..8517
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MSEVKIAPIPDLGQRTDEITIYAGPCSVESAEQFNEVAECVADLG
                     LSWIRGGAFKPRTNPHSFQGLGEEALKIMKAAGDTYGLKTLTEVMDSAHCQLVADYVDG
                     LQVGARNFQNFSLLKKIGQVTAESQQMVLYKRGFAGTIAEWLAATDYITDCGNNNVVLC
                     ERGIRTFETATRFTLDIAAVPVIHKQSLYPVCIDVSHPAGQRDLVPALAKAAVAAGADS
                     LMIEVHPNPPVALSDGPQQLTPAQFRELVAELRELAACLGKKIV"
     CDS             complement(8713..9480)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MAKFLEYVPGTSFLHRMNPSVKLVCAILFAIACFTTSNLIFLGVL
                     LAGAVALAAGCGLGRETAGLMKAVFAFSLILAVVLLLTTPTGAPLVALPWGYLGTGSLL
                     AALTAIVRLEAAAIPLFLVFYVTRMSDITNSAVKQLHVPYKYAFTFTSTVHFIPVFMND
                     MAGIMEAQTARGVAFDGSLAKKMRLMMPLCVPLLVSSVRKTNSAAIAAEVRGFNLRTRQ
                     SGYKDYPLHTEDYLALAACALILTAAIALAVLG"
     CDS             complement(9480..10496)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MIEFKNVSASYDGELAVLRDVSFTVSDGDFVAFVGTNGAGKSTTM
                     RLVNGLLKPTAGEVLIDGVPTGALKTSELARRIGFLFQNPDRQICCATVREELLFGFRA
                     LGEEGPEAEARVDAVIERFGFSPDAEPFLLNRGTRQLLALASIIVLAPPVIVLDEPTTG
                     LDFRECEKVMAVVRELNEQGTTVIMVCHDMEVVGDFADRVIAMTAGRVVADGPTFEVLR
                     DPAVLAETHILPPQITAIALALERELPACPAPVAAANTVDAMADALAVATTADAGAPAA
                     ERPDPTATPDRPEPAAPGRDGAGMLDELEPDRPDQTAAPGRPAPAAVPDNPNAEGAR"
     CDS             complement(10493..11332)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MIQFRDFSFRYREGADLVVRDINLTIPDGCFVGITGAAGSGKSTL
                     TYAVNGIIPHCYPGDFYGEVSVEGLDTMEASLTDLSQLVGSVCQDIDSQMVATVVEDEL
                     LYGLENFAVPREEIPGRVTEALAAMGIADVRDRTIDSLSGGQKQKVAVASVLALRPRVL
                     VLDEPTAELDPASSVAVFDLLARYAREHGTTVIVVEQKIALLSDYADMLVIVDGGRIRF
                     ADAPEAVLAHADTLLALGVNVPRATTLVNALADRGLYDGPAVRTVAGAVAAAKEVLA"
     CDS             complement(11342..12025)
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MTERTLTPDTETATPQAPAGALRTSDSAAPAGRARTAAGTSAAGE
                     KATGTARGGLSIQDLILVAVLLAAGAVLKLTVGSLLASFGMKPNFVIAAYCLAIILIRP
                     TLAQSAVIGLIAGLVCQIPMLNATPLLNIPSELLGAVACGLLIRVPMKIGGKFDANPLV
                     NTFISTCVSGFTFAALSVYINVVSVGGSFAVAMAAYVAIVLGTATFNAIFVQILATPLA
                     KVLKR"
ORIGIN
        1 ggtatgatcg cgcatggagg gtccttcctc tccgtctccg gcctagacaa cccgagagga
       61 tacaggaggg gccctcttcc tgtggcacag gggagcgacc cggaatccgg acaaagttaa
      121 ctcacactcg ggcccggggc tgttctggac gtggcccgtc atggaggcga acaccctgcg
      181 agtggacacg cgcacgcggg tgaccacctt ctacgccgag gagaccctca cggccgatct
      241 ggtgcccctg gatgtggacg ccgtgctgtt ctggcacgtg tgggacgcga aggcggcctg
      301 tctggaagtg ggcgacttca tccgggccgt ggagatggcg gcccaaacgg ccctgcgtga
      361 cgccatcggc cgggcggggg ccgccgaggt ggccatccgc cgcgagcagc tggaccgcga
      421 gctcaaacgg gtgctggagg agaagacggc gccctggggc gtgaccgtgc tgtcggtgga
      481 ggtgcgcgac attttgctgc ctcgcgagct gcaagaggcc atgagcctgg aggcccaggc
      541 cgagcagcgc aagaaggccc gcatcatcct catggaggcg gagcaggaca tcttcgagac
      601 cctggccgag atggaggact tggtgggcgg ccccgaggcc gtggggcgtc tgcgcaccat
      661 gcacctgctg aacgagtcgc tgcgcgaggg caagggcacc gtggttatcc ccagcgcctt
      721 cgccgagggc ttcaacgagg gtgtgggcga cctgatcaag gggtagggtt cgaggcgtcg
      781 tttggcacgg agcgcctttc tacaagcagg ccgcttggtt gaagggacgg attcgcttga
      841 gttcgggctc gagcttgcgc cgggcgattt ccagatcgta ggcctcctgg gcgcgaagcc
      901 agtagccatc ggtgagaccg aagaagcggc agaggcgcaa gtcggtatcg gcagtgatgg
      961 tccgacgtcc gaggacgatc tggccgatgc gctgcgccgg cacgccgatc tctttagcaa
     1021 gtcggtactg cgacagaccc aggggtttga ggaattcctc ggagagcagc tctccaggcg
     1081 ttatgggatc gagaaggtcg ggcatgatgg cctcctagtg gtagtcggtt atctgaacat
     1141 ctgtgggccc cgctgccgtc caacgaaagc agatgcgata ttggtcgttg atccgaatgc
     1201 tccaaaaccc ttcgcgatcg cccgataact tctcaagatg gttgccaggc ggtatgcgaa
     1261 ggtcctggag gtcgcctgcg atctccagtt gccgaagttt tcttcgcgcc acacgttcaa
     1321 aggcgacgaa ccgttgaaca cgctgtccgc gagcgagtag ctctgtgctc ttgtccgcaa
     1381 acgttctgat cataataact ccttgcgtta ataacgtcaa gcatgattaa atgatttggg
     1441 attgatatta taatacgaat aaatgtttgg tattcaagtc ttgactttcg cttgagtgcg
     1501 atgtggccat cggctgccac atcgcacggt aatgcggttt tgcatatatc ctcaagaaag
     1561 atagtctgct gcaaaaattg tcctatgata atccttgcat tgtcatagga caatttgcta
     1621 tgatgcgccc ggaagaattt ggccaattct tacggattac cagttagaga ggggcagaag
     1681 cgctcgcatg aggagatgcg ggccgcgagc accgaacgga ttatcgcgcg gacacgaaac
     1741 ggagtgtccg caaggacgga tgccagctcg ggcgcgtcgc cgacaagggc gacggccggc
     1801 gaaaggagcc cgcctgcgat accgcgcggc gcagccctca gggaattcaa aggaggagag
     1861 atgtcgggag cacgaaactc cacgctcacc cgcaggagct tcctcaagac gacgggctcg
     1921 gcggccgccg ggctcgcctg cgtgggcgcc gctggtgctg ccttgagcgg tgaggtgctg
     1981 gcccctgccc gggcccatgc agagggagag gagcgcacgg ctcatctgtg ccaccagttc
     2041 cattgcttga cgggatgcaa tctgaaatgc accattcgcg atgaccgcat cacgctgatc
     2101 gagccgagcg acttgatggt cgacaagaaa cactcgacca tctgtctgcg cggcatcggc
     2161 gaggtcgcgc acatttacgc acaggatcgt ctcaaggtgc cgatgaagcg cgttggcgaa
     2221 cgcggcgagg gtgaattcgt ccagattagc tgggacgagg ccatccagac tatcgccgac
     2281 aacctgaagg aggcccagca gaaatacggc gagggatcgg tcttcatccg caagtccacc
     2341 gaggcgggta tagaattcga cttcctggcc cagctgatcc atgcggattc tggcggcaac
     2401 tggggactcg accgcggcca ggccaacggc ctgggaccgg ctctgggccc gtggagctat
     2461 ctttcgaacc gctcccactg ggagttcaag gatgcggcca ccattatcga gctgagccac
     2521 aatcccttgg agagcgccat ggtatggtcg cgcccgctga tggatgcgaa ggaggcgggc
     2581 acctacatcg tgaccatcga cccgcgcttc acaggcacgg cggcgaaatc caacgagtgg
     2641 cttcccgtgt gtcccggtac cgacgcggcg attatccagg gcatgctgaa ggccatcgtg
     2701 gacaatggct ggtatgacga ggagttcatg ctcagccgca cctcttgccc ctatctggtc
     2761 gatcgcgcca cgggaaagag ctatcgcagc gccgaggtca tggcccccaa cccgaccgtg
     2821 gtcggcgccg agcccgtggg ggctcccttc gtgtgggaca ccgtgaccaa tgccccggtc
     2881 ctgtacgaca acgcgaccgc tgtgccggcc ctcgagggcg agtggacggt ggacggcatg
     2941 cagctggtca ccgagttcac gctcatcaag gagtggctgg atacgatcac gcttagttgg
     3001 gccgcgcaga cgtcgggcat cgacgagcag gttatcgtga acttggccga ccgctatgcc
     3061 aacaacggcc ctgccattat cgacatcggg ctgggtggtg ccgacaagta caccaacgcc
     3121 gatgtgctgg gccactcgac ggctctgctg gtggccttga ccggccagta cggcaagaag
     3181 ggcgcgggcc tcggctccta ttgcggcttg ggctccaatg atccttcggc aacgctcaac
     3241 tactgggttc ttcccgagga gtaccactac ggggaaagcc cggttgccat gtacgacatg
     3301 ccctaccagg agaacaacat tcatgcggcc ctgacattcg gcgatgcgtt cacccttgag
     3361 gccggagcgg cgaacgacat gctcgagtgg gtgaagtccc tcgacttctt cgccatcgtc
     3421 gacctgtacc actcatcggc ggtggactac gccgacatcg tattgccggc ctgcacgaaa
     3481 ttcgagtgcg aggagaacgt gaagcagctg cgcgacagca tgggccacgt gatgctggcc
     3541 aacggcatgg tcgccccgct gttcgaatcg aagagcgact tgcagatcga gcgcttgctc
     3601 gccgcccagt ggggccttga ggatctgctg cccgagacct acgaggagct tgcgcggttc
     3661 atgctcgacg gcgcagcgga gctcgacccg cgcatggagg gcatcaccta cgacgctctg
     3721 ctggccaacg ggggcgtcat ggccctgccg gaaaccggcg aagactacct gcccgacgga
     3781 ttggccgagg gcttcctgac gccttctacg cgcatcgagc tgtactacga gtatttggcc
     3841 gatcagggtc atgggctgcc ggtttacgag gatgcgaacg aggcctacga gagcaatccc
     3901 aagaaagagc agttcccgct gtacttcacc cagggcaaga gccgttatcg catccatgcc
     3961 tactactctg cgaacgagtg gttccaggag gacttcggcc ccagcctgaa catggcaccc
     4021 gaggatgccg aggctcgcgg catcgtcacc ggcgacgacg tgcgcgtctt taacgatcgc
     4081 ggctccttcg tggcgacggc gctggtaaac cgctcgctgc agccgggcgt gctcttcatg
     4141 gccgagacga cctacacgcg ctactacaag gaagggttct tgcagaacgt gaccaactcg
     4201 gcgcggctcg agcgcggcta ttcgatgttc ttcggccccc agattcccta caacgatgtg
     4261 ttggtggaag tagagaaggc gtaggtgaaa tcatgacgag atacggaatg gccattaacc
     4321 aaacgcgctg cattggctgt cagacgtgcg cttttgcctg caagatgcag aatggcgtgg
     4381 cgaaggatat gcgctggaac cgcgtgctta ccgaaggggg cggggtggca gacgacgccc
     4441 aagggcagta cccgaacctt acgcgcacgt acctgccgct ggcgtgccag cattgcgaga
     4501 accccgcctg cttgaaggcg tgccccaccg gcgccaccta caaagacgag gtgggtcgcg
     4561 tggaaatcga ctatgacaag tgcatcggct gccgcatgtg catggccgcc tgcccctaca
     4621 acgcccgctc cttcaactgg gcagagccgg cattcgtgcc cgatttcgcc tatggcgacg
     4681 ggcaggtcga gcgccgggaa cggggcgtgg ccgagaagtg caccctgtgc aaggagcgca
     4741 ccgaccgcgg cgaggagccc cgctgcgtgc agtgctgccc gctggatgcc cgcatcttcg
     4801 gtgatctgga cgacccgaac tccgaggtgt cgaaggtcat cgtcgagcgc aaggcccgcg
     4861 tgctcttgga ggagcagggc acccgcccgc aggtctacta cttcgaatag ggagcgagaa
     4921 aatggaactg ttcaagcgaa acaaagcagc tacggcggta ctgatcgtgc tcgcctgcgt
     4981 cggcgtgggc gcctggatct accagctcat gggcggcctg gccgtgaccg gcatgtccaa
     5041 cggcgtgtct tggggagcct acatcaccat gttcatgttc ttcgtgggcc tgtcggccgg
     5101 aggcctcatc gtggcctcct cggccagcgt cttccacatc aaggcgttca agcaggtggc
     5161 catgccggcg gttattctgt ccacggtatg catctgcctg gccggcatgt tcgtgctcat
     5221 cgacctgggc ggcattcaac gcgtgtggcg cgtcgtgacc ggtccgaacc cggcgtcgcc
     5281 tttggtgtgg gacatctgcg tcatcacctg ctacctggtc attaacatcc tgtatctgca
     5341 cttcatgcgc aagggggccg agcgcgccgt ggccatggtg tctcgcttcg ccctgccctg
     5401 cgccattctc gtgcactcgg tgaccgcctg gatcttcggc ctgcaaattg ccaaggaggg
     5461 ctggttctcg gccatcatgg ctcctatctt catggcgagc gccatggact cgggcctggc
     5521 cctgctgctc atcgtgctgt cggcgctgaa cgcctcgggc cgctttaaga cccccaagga
     5581 gctcatcgcg agcctggccg gccttttggc cacctgcatc gcggtggatg cctacttcat
     5641 cttctgcgaa gtgctgacca tgggctatcc cggcgccgcc ggtgccgaga cgctggccct
     5701 catggtgacg ggtcccaccg ccccgttctt ctggttcgaa gttatcggcg gcctgctcgt
     5761 tcccttctgc gtgctggtct tcgcgaagaa ccgcgcgaag acggggcttg tggtgggcgc
     5821 gagcgtgctg gtggtggcgg gcgtgctgtg caagcgcgtg tggctgctgt tcacctcgtt
     5881 catcggccag aatgtggccg gcgccccggg tgtgatgacc gccgacggct gggcgatggc
     5941 cggctcctat gcgcccacgc tcgtagaggt gaccatcatt gtgggcgtag tgtcggtggg
     6001 cgccctcggc ttcatggccc tggcctcgaa gctgcttcag cccgcggctg aggaggagac
     6061 ggttccggct gcgacctccc gcaccagcgc ccccgagctg gagttcgacc cgcaggtggc
     6121 gtaaacgagg aagagatggg aagggggttt ggaacttcgc ggttgggtgg aggctctgaa
     6181 cccctgcggc tcggtcgccg ctcttccgag ttacaaccta gaacgtttcc aaccgggcct
     6241 ccgtgctgca acggaggccc ggttttcatg tcttgatggc ccggggtacc gaagttgtca
     6301 gatcgtcaac ggaatgatgt ccgccgagcg gcgttggtta cgtaacagtg acggggctag
     6361 cccctgttca accggttgct ttcaaggccc atgcggtgag cctgattttg tgcgcgcgcc
     6421 ttaacatggt gtccatagga gatggttccg attggctcgc accgtaggga gggcggtggc
     6481 acaacggcag gaaccaggat gcgggcgtta cgggcgccga gcgataggag ttgccttatg
     6541 gagaagattt tggatctggt gcggtcgaac aacctggtgc aggcggtgct gtgcatagcc
     6601 ttcggcttgt tcctcatgat ttatccctcc ataactattc agggcatcat catgctgttc
     6661 ggcgtggccc tggcgctcat gggtgcggcc ggtctggtgt cctacttccg ccagaagagc
     6721 gtgcgctatc gcaatacggg taccctcatg ggagcggtct tctacctcat catcgccctt
     6781 atcgccttcg tgtttcccaa ggtgattgcc gggttcttct cggtggtgct cggtgtggtg
     6841 ctcatcctgt tcgccatcgt gaacgtggtg cgggccctgg ggttgcgcgc cttcgggggc
     6901 agtatctgga tcgccgtgct cgtggccgcc gtcatcgtgg gcgtcggcgg tgtgctcatt
     6961 gtggtgaatc cctggggcgc ttccatgacc ttcgtgctgg tgctgggtgc ggccttcatc
     7021 gccaacggtg ccgtggacct gttcatcgaa tggtacgccc gcgactccgc caagcaggcc
     7081 gacttgatgg cgcggccccg ctaaggagcg aggcggccgg cgcgagggag gtgccggact
     7141 gcgtgccggc tccgtcgcct tagagcgcgc tgctcgggcg gtcaccccgc tgatcgagcc
     7201 gtgtctcggg ctcggacggc accgccgcgc tggcgttccc cgcccccttg cgcatcccgc
     7261 tggctcgcat tcgattttgc cgatggcggc ccgtcgcggg cttctataac ttaattgctc
     7321 catgacccct gctcgcgcgg gggtctttgc tatcatggac gccacgcgag ggccgacgtt
     7381 gccgtgacgg cgcgccggcc atgctcgttc aagtttttgg tacacgaaag gaaaagcgat
     7441 gtctgaagag aacagcaatc ttgccgagat tcagaagcat cgtgagcaga tcgacgccat
     7501 tgaccgcgag atcgtcgcgc ttttgaacaa gcgtgccggc cactcgctgg tcattcgcgg
     7561 tctgaaaccc ggtgcgcata tgggtctgta cgacgcgcgc cgcgaggagg agatcttcgc
     7621 gcgggtggac agctacaacg aggggccgct gtacaacgag aacctccgcg agatttatgc
     7681 caccatcctc aagatcatga aggagacgcc gtccgtatga gcgaagtgaa gattgccccc
     7741 atccccgatc tcggccagcg cactgacgag atcaccattt acgccgggcc ctgctcggtg
     7801 gaatcggccg agcagttcaa cgaggtggcg gagtgcgtcg ccgatctcgg tctttcctgg
     7861 atccgcggtg gcgccttcaa gccccgcacc aacccccatt ccttccaggg cttgggcgaa
     7921 gaggcgctca agatcatgaa ggccgccggc gacacctacg gcctgaagac gctcaccgag
     7981 gtcatggact cggcccactg ccagctggtg gccgattacg tggacggcct gcaggtgggc
     8041 gcccgcaact tccagaactt cagcctgctg aagaagatcg gccaggtgac cgccgagagc
     8101 cagcagatgg tgctgtacaa gcgcggcttc gccggcacca tcgccgaatg gctggccgcc
     8161 accgactaca tcaccgactg cggcaacaac aacgtggtgc tgtgcgagcg cggcatccgc
     8221 accttcgaga cggccacccg cttcacgctg gacatcgctg cggtgccggt catccacaag
     8281 cagtcgctgt atccggtgtg catcgacgtg tcgcacccgg ccggccagcg cgacctggtg
     8341 ccggccctgg cgaaggcggc cgtggcggct ggggccgact cgctcatgat cgaggtgcat
     8401 ccgaacccgc cggtggccct gtccgacggc ccccagcagc tgaccccggc ccagttccgc
     8461 gagctcgtcg ctgagctgcg cgagttggcc gcctgcctgg gcaagaagat cgtgtaggca
     8521 gtttcccctt tcgggagatc gcaaggccct cgacgccgat ggcgcgaggg cctttttcgt
     8581 gcgcgggggg gggtggatgc ggtgcgcgcc cgtgcatgcc cgtgcgctcg cgagaggggg
     8641 atggagcccg cgccgttcac aggctctcgc acatttcggc atgatgccgc tggttttgcg
     8701 gcgcgcggcg ggctatccca ggacagccag ggcgatggcg gcggtcagga tgagggcgca
     8761 ggcggccagg gccaggtagt cctcggtatg cagggggtag tccttgtagc cgctttggcg
     8821 ggtgcgcagg ttgaagccgc gcacctcggc ggcgatggcg gcggagttcg tcttgcgcac
     8881 ggagctgacg agcaggggca cgcacagggg catcataagc cgcatcttct ttgcgagcga
     8941 gccgtcgaag gccacgccgc gggccgtctg cgcctccatg atgccggcca tgtcgttcat
     9001 gaacacgggg atgaagtgca ccgtggacgt gaaagtgaag gcgtacttgt agggcacgtg
     9061 cagctgcttc acggctgagt tcgtgatgtc gctcatacgg gtgacataga acacgaggaa
     9121 cagcgggatg gccgccgcct ccaggcgcac gatggccgta agcgctgcca gcaagctacc
     9181 ggtaccgagg tagccccagg gcagggcgac gaggggcgct cccgtcgggg tggtgagcag
     9241 cagcaccacg gccaggatga gcgagaacgc gaagacggcc ttcatgagcc ctgcggtctc
     9301 gcgccccaat ccgcagccgg cggccagggc cacggctccg gcgagcagca cgcccaggaa
     9361 gatcaggtta ctcgtggtga aacaggcgat ggcgaacagg atggcgcaga cgagcttcac
     9421 cgatgggttc atgcgatgga gaaagctcgt gccgggcaca tactccagga acttggccat
     9481 tatcgggctc cttctgcatt ggggttgtcg gggaccgcgg ccggggcggg gcgcccggga
     9541 gccgctgttt ggtcggggcg gtcgggctcc agctcatcca gcatgccagc gccatcgcgc
     9601 ccgggggccg ccggttcggg gcggtcgggg gtcgctgtcg gatcgggacg ttcggcagcg
     9661 ggcgcgccgg cgtcggccgt cgttgcgacg gcgagggcgt ctgccatggc gtccacggtg
     9721 ttggctgcgg ccacgggcgc ggggcaggcg ggcagctcgc gctcaagggc gagggcgatc
     9781 gcggtgatct gcggcggcag gatgtgggtc tcggccagga cggcggggtc gcgcagtacc
     9841 tcgaaggtgg ggccgtcggc caccacgcga ccggcggtca tggcgatgac gcgatcggcg
     9901 aagtcgccca ccacttccat gtcgtggcag accatgatga cggtggtgcc ctgctcgttc
     9961 agctcgcgca ctacggccat gaccttctcg cactcgcgga aatcgaggcc ggtggtgggc
    10021 tcgtccaaca cgatgacggg cggcgccagc acgatgatag aggccagggc cagaagctgg
    10081 cgggtgccgc ggttcagcag gaagggctcg gcatcgggcg aaaagccgaa gcgctcgatg
    10141 acggcatcga cgcgggcctc ggcctcaggt ccctcctcgc ccagggcgcg aaagccgaag
    10201 agcagctcct cgcgcaccgt ggcgcagcag atctgccggt cggggttctg gaagaggaag
    10261 ccgatgcgtc gggccagctc gctcgtcttc agggcgccgg tgggcacccc gtcgatgagc
    10321 acctcgccgg ccgtgggctt cagcaggccg ttgaccaggc gcatggtggt ggacttgccg
    10381 gcgccattgg tgccgacgaa ggccacgaag tcgccgtcgc tcacggtgaa gctgacatcg
    10441 cgcagcacgg ccagctcgcc gtcgtagctg gcgctgacgt tcttgaactc gatcatgcga
    10501 gcacctcctt cgcggcggcc acggcgccgg ccacggtgcg caccgcaggc ccgtcgtaca
    10561 ggccgcggtc ggccaatgcg ttgacgaggg tggtggcccg gggcacgttc acgcccaggg
    10621 ccagcagcgt atcggcgtgg gcgagcacgg cctcgggcgc gtcggcgaag cggatgcggc
    10681 ccccgtccac gatgacgagc atatcggcgt aatcggacag cagcgcgatc ttctgctcca
    10741 ccacgatgac cgtggtgccg tgctcgcggg cgtagcgggc cagcaggtcg aacacggcca
    10801 ccgacgaggc ggggtccagc tcggcggtgg gctcgtccag cacgagcacc cgcgggcgca
    10861 gggccagcac tgatgccacg gccaccttct gcttctggcc gccggacagg ctgtcgatgg
    10921 tgcggtcgcg cacatcggcg atgcccatgg ccgcgagggc ctcggtgacc cggccgggaa
    10981 tctcctcgcg gggcacggcg aagttctcca ggccgtagag cagctcgtcc tccaccacgg
    11041 tggccaccat ctgggaatcg atgtcctggc acacgctgcc cacaagctgg gacagatcgg
    11101 tgagggaggc ctccatggtg tcgagcccct ccacggacac ctcaccgtag aagtcgccgg
    11161 ggtagcagtg ggggatgatg ccgttcaccg cgtaggtgag ggtggacttg ccgctgcccg
    11221 ccgcgccggt gatgccgacg aagcagccgt cgggaatggt caggttgatg tcccgcacca
    11281 ccagatcggc gccctctcgg tagcggaagc tgaaatctcg gaactggatc atggcgttct
    11341 cctagcgctt caggaccttg gccaggggag tggcgagaat ctggacgaag atggcgttga
    11401 aggtggcggt gccgagcacg atggccacat aggcggccat ggccacggcg aagctgccgc
    11461 cgacggagac gacgttgatg tagacggaca gggcggcgaa ggtgaagccg gacacacagg
    11521 tggagatgaa ggtgttcacg agggggttgg cgtcgaattt gccaccgatc ttcatgggca
    11581 cgcggatgag aaggccgcag gccacagcac cgagcagctc ggaggggatg ttcaagagcg
    11641 gcgtggcgtt cagcatgggg atttggcaga cgaggccggc gatgaggccg atgacggctg
    11701 actgggccag ggtggggcgg atgaggatga tggcgaggca gtaggcggcg atgacgaagt
    11761 tcggcttcat gccgaaggag gcgagcaggc tgcccacggt gagcttcagc acggcaccag
    11821 cggccaggag cacggccacg agaatgaggt cctggatgga caggcctccc cgcgccgttc
    11881 cagtggcctt ctcgccggct gccgaagtgc cggcggcggt gcgggcccgg ccggccgggg
    11941 cggcggagtc gctggtgcgc agggcgccag cgggagcctg gggggttgcg gtctcggtgt
    12001 cgggggtgag ggtgcgctcg gtcatgacga tcagtccttt ctcggcggcg cgtacggggc
    12061 cgcctgtcgc gctcgcttgc tcgcgagcct gccagtggat agcaattgcc ccgtatccga
    12121 cgccttcgag aggttccggc cgcaccccaa acaaaaagag ttaaggctca aaaagtgtgc
    12181 tccccacgat gagtaaccgc gaggtcgtgc tcgataaatc gacgccgcaa gttgctccgc
    12241 gccaacttct cactggctca aaaagcgtgc tcccgtagct gttg
//
