LOCUS       NC_021085.1            21098 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021085.1 Cutibacterium acnes HL096PA1, complete sequence.
ACCESSION   NC_021085
VERSION     NC_021085.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:18:41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 834161
            Orig. end    :: 855259
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..342)
                     /locus_tag="ctg1_769"
                     /transl_table=11
                     /translation="MSQTITDTARYSFHVTWSPEDAEFIATCVEFPSLSWLAGTPEKAL
                     TGLRIVVDEVVDDMRANDEPVPEPLSTRHYSGKFQLRLGEDLHRRLVIEAAEQHLSLNQ
                     YVTRKLAVS"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[843824:847272]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9664..13111
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="3"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(342..554)
                     /locus_tag="ctg1_770"
                     /transl_table=11
                     /translation="MRANPRTTMQTCSACARSSSEQPGTTGGSHAVFKTPWLGDLRVNI
                     QNDHGKAKTYQVRQVLQAIEKLKEQ"
     CDS             948..1607
                     /locus_tag="ctg1_771"
                     /transl_table=11
                     /translation="MGGFRSLGIRPIISRVITEPTAPTRRRIKKRHLIEFIKFGVVGGS
                     GFLVNIIVAIIMNKANGGTEHAQDILFNLAGTRWNFRFTSLVWLVGFVVANITNFQLNR
                     SWTFKREYRRGWWREFWPFFAVGSIAAIIGMFIKIFFTNPTSPIYLPEPWFNEGRGIQS
                     REYWSQIFAIIVTMPINFVVNKLWTFRAVKHSGELPMVASAVVPESYDDGDAAESR"
     CDS             1667..1834
                     /locus_tag="ctg1_772"
                     /transl_table=11
                     /translation="MVVFIIAMVLILAVALGVCAVVMLGLRHPGADPDASFWRHTATRV
                     GEDLSGVRHR"
     CDS             1885..3075
                     /locus_tag="ctg1_773"
                     /transl_table=11
                     /translation="VNPITLIWIILGILVLVTVVAAVTAGVSRRKALREGSKPAQVSPA
                     PTESGKTVPEAETPAGGESAVGRPESEASQVAEPAVEAPEAPGSRMARLRRRLANSNNA
                     LARGLAELLSADKLDDDAWDDFETTLITSDLGVGPTTELVEKLRSELAIDGISDPAHAR
                     EVLHHELVELVGSDMDRSINLDRLEGKPAVVLMVGVNGTGKTTTCGKLARVLVAEGKTV
                     LLGAADTFRAAAGEQLETWGERVGVRTVRKDAGADPASVAYEAVQTGIDEGVDVVLVDT
                     AGRLHTKAGLMDELGKVKRVIEKLAPVSEVLLVLDATTGQNGLAQARVFSEVVDVTGIV
                     LSKLDGSAKGGIVVQVQRELGVPVKLIGLGEGADDLAPFDADNFVTGLMGDDSAEC"
     CDS             3086..4267
                     /locus_tag="ctg1_774"
                     /transl_table=11
                     /translation="VTDIAWFAPTGGVMMVSILSHKLCVAVLIAAFALPLAFVVWRAIA
                     GTGSWWRKILRGLGHLVVILLAQALLITGVFLYINREYGFFTSWSDLLGEVQPEAPTHD
                     LVPIRRTKVKDIPISKSNPHPNGQVSAITVPGADAQYARVPVWLPPQYFEKSERRTRFP
                     VLFYIGGVNDTGQRDNKSIDFIGPATELIKGRKVNPFVIVFLPGKIRDGVDSECVDVGP
                     YRHETWIMKIVIPRLESHYRVGHERGSRFIGGWSTGGYCAANLSTKYPRAFNAGFSLGG
                     YYHPMFENPRIANMARPLMANSSVVRRVQERKIERSVRFLSVLNPNDLQSWGPGRVPVV
                     SNGQVGPDGGQFYHVAKGMKQFTFILLTGGGHRVSVYTPYIEQSLQWLGQFGL"
     CDS             4343..5929
                     /locus_tag="ctg1_775"
                     /transl_table=11
                     /translation="VFDTLQDRLASTFKGLRGKGRLTDADIDATTRQIRIALLEADVNL
                     SVVKEFVAAIKERCHGEELSKALNPTQQIVKIVNEELVEILGGQTRTVRFAKTPPTIVM
                     LAGLQGAGKTTLAGKLARWFKEEGHSPLLAACDLQRPNAVTQLQVVGERAGVHVFAPEP
                     GNGVGDPVQVARDAVAEAEHKLYDVVIIDTAGRLGVDAEMMAQAADIKTATDPDETLFV
                     VDAMIGQDAVNTAVAFQEGVGFDGVVLTKLDGDARGGAALSIARVVGKPIMFASSGEGL
                     KDFDVFHPDRMASRILDMGDMLTLIEQAEKAFDQEQSQAAAAKLMAGKGEFGLDDFLGL
                     MRQMRRMGPMSKIMGMLPGVGQMKGQIENIDEREIDRIEAIICAMTPAERADVSILNGS
                     RRARIANGSGVEVRDVNNLVNRFVDARKMMSQMGQMMGPGAGRMMGSMAKRGSKQSKKK
                     QKNRKGSGNPAKRAAQARQAAKKPQRSSGEAFGLQGQQQPSQEDLQKAMSEFKMPPSMQ
                     QMFNQTNKRPR"
     CDS             6006..7169
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_776"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.7e-12, bitscore:
                     43.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEDTQPLFHTHTHDGWTHTHMAREAQTAPDEDLRIRGVVLPDGE
                     ERELWVHDGVLVEGPLSGARTLADGCWIIPGLVDAHNHIGLDAHGAVGTETADEQARTE
                     AKTGTLLIRDAGSPSDTHWIDDRDDLPRVIRAGRHIARPKRYIRNYAAEVDPENLVAEV
                     DRQARSGDGWVKLVGDWIDRDEGDLAPLWPADIAQAAIDRAHELGARVTAHCFSEEAPA
                     QLVDAGIDCIEHGTGLTDETIATMAEREVGLVPTLINIETFPSIAAQADGKFPKYAAHM
                     RHLHTHRHETIAKAWDAGVPIYAGTDAGGTIKHGLIASEVRLLAAVGGAEMALGAASWR
                     ARAWLGGEQLGIGDSADLLVLDRDPRVDVGVLESPTYIVLRGRVVIR"
     CDS             7360..7803
                     /locus_tag="ctg1_777"
                     /transl_table=11
                     /translation="VATKIRLKRLGKIRTPHYRVVVMDSRAKRDGRAIEEIGQYHPKAD
                     PSVIVIDSERVQYWLGVGAQPTEAVVALLKRTGDWQKFTGDTSPSGVKPQPERPNKDDL
                     FNAALAEADEAPREAITKKSEGAAADEASESAAGDNSGEKAEA"
     CDS             7806..8084
                     /locus_tag="ctg1_778"
                     /transl_table=11
                     /translation="VLADALEHLVSGIVANPDDVRVREKDLRRGRMLEVRVNPSDIGKV
                     IGRQGRTASSLRTVIGALAGDEQIRIDFVDVDRRGSGRHSDHRGHRH"
     CDS             8192..8731
                     /locus_tag="ctg1_779"
                     /transl_table=11
                     /translation="VEESATVEVVVGRVGRAHGLRGDVVVEVRTDEPDARFGVGATVQI
                     EGSRRDLTVVRSRWAKGCLIVAFDEVKDRQGAEELRGSVLVVDVEPNDDPDDPDEFWDR
                     RLRGLTVVDESGKSRGAVKDVLHMPAQDVLVIDVSGEEHLVPFVHQLVPTVDVASGRIV
                     VSGIPGLLDSNAEEAR"
     CDS             8734..9453
                     /locus_tag="ctg1_780"
                     /transl_table=11
                     /translation="MRLDYLSIFPAYFDVLDISLLGKAAVNGLVEVHAHDLRDWTHDRH
                     RTVDDTPCGGGAGMVMKPDPWGEAFDEIIGTEPDSSVHVIFPSPSGAPFTQSAAQELSS
                     AVRIVFCCGRYEGIDHRVIDYARSMWTVHEVSLGDYVLNGGEVAALAITEAVVRLVPGF
                     MGNPESLAEESFSAGQDGLLEYPLFTRPVSWRGLDVPEVLMSGHHGRIAKWRRDESVRL
                     TCERRPDLTDSDFGVPH"
     CDS             9664..10314
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_781"
                     /sec_met_domain="SucD_FumR (E-value: 2e-10, bitscore: 37.6,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTGLILILFLLMHMFGNLKLLASNEEFNRYAGFLRTILNPILP
                     GESFLWIFRIFMLLAIVLHIWSAIRVNKQRNIGTGGAGRYSVKKNLSPENTYAARTMFW
                     GGWIIFLFLILHLLQFTISPDLLNNPPTDAAGRAGMVLTAFSHWWFVLIYLIAMIAVCM
                     HVSHGFWSAFATLGVNVSGTARAVLRVCSWIVAIVIFVGFMTPPFLVLFGVIS"
     CDS             10314..12341
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 186.1; E-value:
                     4e-57)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_782"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.5e-55, bitscore:
                     186.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-35,
                     bitscore: 119.4, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAVSNNNAALADQYWTTGDEIHDTKANHDLPIEKIWTDRQFT
                     SRLVNPANRRKMTVIIVGTGLAGGAAAATLGEAGYRVENFCYQDSPRRAHSIAAQGGIN
                     AAKNYKNDGDSIYRLFYDTVKGGDYRSRETNVYRLAAVSANIIDQCVAQGVPFAREYGG
                     LLDNRSFGGVQVQRTFYARGQTGQQLLIGAYQALERQVHAGTVHMHTRHEMVELIVADG
                     RARGIVTRDMVTGKIEEWFGDAVVLATGGYGNVFFLSTNAMGCNATASWRAHRKGAYFG
                     NPCYTQIHPTCIPVHGENQSKLTLMSESLRNDGRIWVPKRAEDCEKDPRDIPEEDRDYY
                     LERIYPSFGNLVPRDIASRQAKYRCDEGRGVGPKVREVDSDGTEHMRARGVYLDFSEAI
                     QRMGKDAVEKKYGNLFDMYQRITDENPYEVPMRIYPAVHYTMGGLWVDYDLQSTIPGLF
                     VCGEANFSDHGANRLGASALMQGLADGYWVLPNTITDYLADSPKFGMVDEKHPAAVEAR
                     QAVESRINKLLTINGTRTVDSIHKELGHIMWEYCGMERSEAGLIKAIGLIRNLRNEFWT
                     NVKVTGVNEELNQTLERAGRLADFLELGELMCIDALHRRESCGGHFRAESQTEEGEAMR
                     HDDEYQYVAAWEWTGEGHKPTLHKEPLVYKSIQVKQRSYK"
     CDS             12338..13111
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 4.4; E-value: 0.13)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_783"
                     /sec_met_domain="Fer4 (E-value: 2.3e-07, bitscore: 27.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.9e-07, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 7.6e-24, bitscore: 81.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.7e-11, bitscore: 41.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-06, bitscore: 23.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLT
                     AQGEEPVAFDSDCREGICGQCGIVINGVPHGGMGVAQPVRTTTCQLHMRSFADGSTITI
                     EPWKSGAFPILRDLIVDRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFDAAT
                     CIGCGACVAACPNGSSMLFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNI
                     GECASVCPKGIPLESISQLNRDLIASLFKHDGKDD"
     CDS             complement(13132..13329)
                     /locus_tag="ctg1_784"
                     /transl_table=11
                     /translation="VLVFTKISFPERRTVPLWQEPDTDNTAVFFHTHGSGIKSTITRAR
                     QQAVLHNITGLRHREVSEPE"
     CDS             13362..13715
                     /locus_tag="ctg1_785"
                     /transl_table=11
                     /translation="MSNIIDEIDKASMRDDIPEFRPGDSVKVHVKVVEGSRTRVQVFSG
                     IVISRTGGGVQESFTVRKLSFGTGVERTFPLHSPIIDKIEVDRHGAVRRAKLYYLRGRR
                     GKAAKIKERGSAR"
     CDS             13886..14710
                     /locus_tag="ctg1_786"
                     /transl_table=11
                     /translation="VADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIV
                     VGALIISAVLRGFVAQMFVIPSKSMQNTLQVGDRVIAVKAADFHRGDVVVFKDTEHWLP
                     AAQDRRSVPGQILEFVGLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALDERS
                     YLYSENGEMVKPSAMEFRVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVP
                     LDDVVGPAKAILMPLNRIEGLGTPDIFRGIPDRSSSAPGKARICVGNACCPK"
     CDS             14719..15360
                     /locus_tag="ctg1_787"
                     /transl_table=11
                     /translation="MSVRVGSGPMGHERALARAGLGPVAGCDEAGRGACAGPLVAAAVI
                     LDDRRSGRIAGLADSKTLSAAKREALFNVIMDKALAVSWVGVEADECDRLGMQEADISG
                     LRRAVVRLGVEPGYVLSDGFPVDGLTVPDLGMWKGDSVCACVAAASIVAKVARDRIMIA
                     MDAEIPGYDFAVHKGYATALHQRRLKELGPSRQHRMSYANVRRAARLHSS"
     CDS             15357..15668
                     /locus_tag="ctg1_788"
                     /transl_table=11
                     /translation="MSAEDLEQYENRMELELYREYKDVVGIFKYAVETERRFYLCNVVD
                     LKVRTEGGDVYYEVSMADAWVWDMYRPSRFVKSAKILTFRDVSIEEIVHADFDEVPSK"
     CDS             15934..16356
                     /locus_tag="ctg1_789"
                     /transl_table=11
                     /translation="MMTPKPLSAELTTPRGAALRGRRGCRPAFGAWGEDLAAQYVESLG
                     WTIIARNWTCDVGEIDLIARDDQTVVFIEVKARLGTGFGDPLESITTAKVRKLHELALA
                     WLVNQDDGVHSVRIDAIGVMVRPGAEPTVTHVRGIR"
     CDS             16353..17876
                     /locus_tag="ctg1_790"
                     /transl_table=11
                     /translation="VTGASAWSVALVGMEGSMVEVEAAISSGLPRTVLVGLPDAALHEA
                     RDRCRAAVCATGLSWPSNVLTINLTPAGLPKAGTHFDLAIAAATLAADGKVPQALLGST
                     VLIGELGLDGRVRPVRGVLPALLAAREAGFERAVVPASQSDEASLVEGLMIWPVGHLGD
                     VVDVLHGRPVVPPEGPIVGSPDTDPGIGDLTEVIGQHEARRALEVAAAGRHHILLRGAP
                     GCGKSMLARRLPGILPRLDHRDALEVTALHSLAGRGSGRLMTRPPLAQPHHSVSMAAMV
                     GGGVRIAQPGAISLAHRGVLFLDEAPEFAPKVLDSLRGPLETGEIVIGRSQAHTTFPAR
                     FQLVMALNPCPCGLADDPSGRCTCTPQQVRRYSGRLSGPILDRVDVTVRMRPLTSAHLL
                     DASALPAGESSSAVHERVAQARERAAARWRGVPWRCNAEVPGKVLRQMLPANDATRIIE
                     DALTTGRLTARGVDKVLRIAWTVADLEGKDEVDKACVAEAMGMRRERLR"
     CDS             17831..19006
                     /locus_tag="ctg1_791"
                     /transl_table=11
                     /translation="VCGGGHGNATRKIAMTWTSERLARAALTAAAEPGVMAKRLVEMTA
                     EELWQHMLTDSGERWHKRAKSLDVDQLVERSEKAAMRFLIPGDEEWPTGLDSLARVGKS
                     GMGGAPVGLWVTGPAHLADISQRAVAIVGCRSASSYGQDVAVEMAYRLVRGHCDGTGSH
                     TVISGGAFGIDVAAHRGALSARGNTVSVLACGLDTLYPRGNSAVLEQIAGTGALVSELP
                     LGRHPTRPGFLARNRLIAALTTGTVVVEAGWRSGAINTASWANALGNAVMAVPGPVTSS
                     RSTGTNKLIRDGEAILVRDADDVRGIVGELAPEPERPAGRSLPTDILDAIELAVHEALP
                     AHGSCGLDELAVLAGVPVAQCSAALSVLEQLGMAACCLDGTWSVTLARERR"
     CDS             complement(18981..19487)
                     /locus_tag="ctg1_792"
                     /transl_table=11
                     /translation="MTAQSQHRFDTAIGELEVTATAHGLSRLVFVKTDPSPPPLSTSHA
                     RRSGDIISCAIAQITEYLSGSRTSFDVALDLSATTDFQRTVLTGLQTVPYGQTVSYRQL
                     ASIIGRPNASRAVGHACATNPLPILIPCHRVLRSNGQLGGYLGGPRLKRFLLNLESVTS
                     APLPA"
     CDS             complement(19530..19745)
                     /locus_tag="ctg1_793"
                     /transl_table=11
                     /translation="VGLSDKINSKSDEAVGAAKEKIGGLTDDSDLKSAGADQKASGKVA
                     QKVEDVKDKANDLKHNVQAAADKLKG"
     CDS             complement(19962..20387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hydrolase_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_794"
                     /sec_met_domain="Hydrolase_4 (E-value: 8.9e-14, bitscore:
                     48.4, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDFVKNPKAIRMPSGPLSADIILPGYPPYGLCSDPAVRFDHWHR
                     DPLYNHYMRLGLVEQMGVAEAYNVMNAHDFKAPTLIMHGENDGLVPSYFDVNWYNAITS
                     KDKKIIQWHGLMHEIFNEPTKDQVIKTAIDWIDAHNK"
     CDS             complement(20408..20575)
                     /locus_tag="ctg1_795"
                     /transl_table=11
                     /translation="MYPGTVDGIVSSGGGTIVNVDGPDTEGATTITPDNLNFFARHALP
                     QISQLLPMPS"
     CDS             complement(20556..21098)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hydrolase_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_796"
                     /sec_met_domain="Hydrolase_4 (E-value: 3.5e-27, bitscore:
                     92.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFPRKLSALAVASTMAVTGVTMATPALANTGTSSQPAAAAPAIN
                     QVHKETGYFKTTDKLGTQLFYRKDIVPNAKGAVVLVHGLMENSSDYEYLTKSLTNAGYS
                     VYRFDNRGHGRSAAPYINNAIPRGQFDDWWNIESDIHQVVGTAHKENTGKKVFLLGHSM
                     GGIAVHTVLRNHVSRNC"
ORIGIN
        1 tcaggagacg gccagtttgc gcgtgacgta ctggttcaag ctgaggtgct gctccgcagc
       61 ctcgatcacg agtcgtcgat gcaggtcctc gccaagtcgg agttggaact tcccggagta
      121 gtgccgggtg gacaggggct cgggtacagg ttcgtcattg gcgcgcatgt catcaacgac
      181 ctcatcgacg acgatccgga gcccagtgag cgctttctcg ggagtaccgg ccagccacga
      241 cagcgaagga aactcgacgc acgtggcgat gaactcggcg tcctcggggg accaggtcac
      301 gtggaagctg tagcgtgcgg tgtcggtgat cgtctggctc atcactgttc cttcaacttc
      361 tcgattgctt ggagcacctg tcggacttgg tatgtcttgg ccttgccgtg gtcgttctgg
      421 atgttgaccc gcaggtcgcc gagccatggg gtcttgaaga cggcgtgcga gccgccagtg
      481 gttcctggct gctccgaaga actcctcgca cacgcggaac aagtctgcat agtcgtgcgt
      541 ggattggctc gcatggaagc gaggatcttg gcaacgctca gtatggctta atggtactac
      601 atgtggtacc ggggagaagt gactggcgtc ctagaggcgg ggctgctggg gatggttgct
      661 ggcccgatct gatgttcacg tcgccgaaga ggagaaggta agactcgtgt ggctgtatca
      721 acgtgcattg ctgatgtagt tgggttacct cgatcggtcg cttgatgcct ataggtgaga
      781 ggataagcct tgcaagcgtt gtggcaccgt catgagccgt atccagttca tgaaccggag
      841 ctcgacgcgg tgcctgaggt ggcccgctat cccggtccga ggccatatct caccattggc
      901 tgctttcgca gcgtgacgac tcgtcccggc gcgccatatt aatcttgatg ggcggtttca
      961 gatctcttgg cattaggcct attatatcgc gagtgatcac tgaaccgact gcacctacga
     1021 ggagacgcat caagaagcgt cacttgattg aattcatcaa gttcggggtc gtcggtggat
     1081 cagggtttct ggtcaacatc atcgtcgcca tcatcatgaa taaggcgaat ggcggtactg
     1141 agcatgccca ggacatcttg ttcaatcttg cgggtacccg gtggaatttc cgcttcacga
     1201 gcctggtgtg gctcgtcggt ttcgtggtag ccaacattac aaacttccag ctcaatcgtt
     1261 cgtggacgtt caagcgcgaa taccgtcggg gatggtggcg tgaattctgg cctttttttg
     1321 ccgtagggtc gatagccgcc atcatcggta tgtttattaa gatcttcttt accaacccaa
     1381 cgtccccgat ttacttaccc gagccgtggt ttaacgaggg aagggggatt cagtcacgcg
     1441 agtactggtc ccagatcttc gccatcatcg tgacgatgcc tatcaacttc gtcgtcaata
     1501 agttgtggac cttccgagca gtgaagcact caggagagct tcctatggtt gcctctgcag
     1561 ttgttcccga aagttatgat gacggcgatg cagccgaatc gcgttaggga gcctggcgcc
     1621 tcgggtaatc tgcatgtgcg taccctgacg gaaaggtcgg tctcggatgg tcgttttcat
     1681 catcgcgatg gtcctgattc tcgcggtcgc cttgggcgtt tgcgccgtgg tgatgctggg
     1741 tctacgtcat cctggtgccg atcccgatgc tagtttttgg cgtcacaccg ccacccgtgt
     1801 gggtgaagat ctcagcggtg ttcgacatcg ctgaggcggt ctgccctcgt ggttttgtga
     1861 attgaccgac taatatcggc cgacgtgaac cccataaccc tgatctggat tatcctcggc
     1921 atactcgtcc tggtgacggt ggttgctgcc gtcactgctg gagtttcgcg gcgtaaggct
     1981 ctgcgtgagg ggtctaagcc tgcccaggtg tccccggctc ccacggaaag tgggaaaaca
     2041 gttcccgaag cggagactcc agcgggcggc gagtctgctg tcgggcgccc cgagtcagaa
     2101 gcgtcacagg tcgctgaacc agcggtcgag gcgcccgagg cgccaggctc gcggatggcc
     2161 cgattgcggc gtcgtctggc taacagcaac aatgcgcttg ctcgtggctt ggccgagttg
     2221 ctgagcgctg acaagctcga cgatgacgcc tgggatgact tcgagaccac ccttatcacc
     2281 tccgatctgg gtgttggtcc gacgacggag ctcgtcgaga agctgcgctc ggaactggct
     2341 attgatggga tctctgaccc ggcccatgct cgcgaggttc tgcaccatga gcttgtcgaa
     2401 ctcgtcggat cggatatgga tcgttccatc aacctagacc gcctggaagg caagccggct
     2461 gtcgtcctca tggtgggcgt caatggcacg ggtaagacga cgacctgcgg caagctggcg
     2521 cgcgttctcg tcgccgaggg aaagacggtc ctcctcggtg cagcagacac cttccgcgcc
     2581 gccgctggcg agcagctgga gacgtgggga gaacgcgtcg gtgtgcgtac cgtccgcaag
     2641 gacgcgggcg ccgatcctgc ctccgtcgct tacgaggccg ttcagactgg cattgatgaa
     2701 ggtgttgatg tcgtgctcgt tgacactgct gggcgacttc acaccaaggc cggtctcatg
     2761 gatgaactgg gtaaggtcaa gcgtgtcatc gagaagcttg caccggtgag cgaggtgttg
     2821 cttgttttgg acgccaccac cgggcagaat ggcctagctc aagcccgcgt cttctcggag
     2881 gtcgtcgacg tgactggcat cgtgttgtca aagcttgacg gttccgcgaa gggcggcatc
     2941 gttgtccaag tgcagcgtga gctaggtgtg cccgtcaagc tcatcggtct cggcgaggga
     3001 gccgacgatc tggccccctt tgatgctgat aactttgtca ccggtctcat gggtgacgat
     3061 tctgccgagt gctgaggtcc gataagtgac agatatcgcg tggtttgccc cgactggtgg
     3121 ggtcatgatg gtcagtatcc tcagccataa gctgtgcgta gcggtgctta ttgcggcctt
     3181 cgctttgcct ctagctttcg tcgtgtggcg ggctatagcg ggtacgggaa gctggtggcg
     3241 caagatcctg cgcggtctcg gccatctcgt ggtgattttg ctcgcgcagg ccttactgat
     3301 taccggcgtc tttctctata tcaaccgtga gtatgggttt ttcacgtcat ggtctgacct
     3361 gttgggagag gtccaaccag aggctccgac ccatgatcta gtcccgatcc gacgcaccaa
     3421 ggtcaaagat attccgatca gtaagtccaa cccccatccc aacggtcagg tgagcgcaat
     3481 aacggtgcct ggcgcggatg cccaatatgc gcgcgttcca gtctggctgc caccccagta
     3541 ctttgaaaag tcggagcgtc gcactcgatt tccggtgttg ttctacatcg ggggcgtcaa
     3601 tgacactggt cagcgtgaca acaagtcgat cgacttcatc ggtccagcaa ccgaactcat
     3661 caagggcagg aaggtcaatc ccttcgtcat cgtgttcttg ccgggcaaga ttcgtgacgg
     3721 tgtcgacagc gagtgcgttg acgttggtcc ctaccggcat gagacatgga tcatgaagat
     3781 tgttatcccg cggcttgagt cgcactaccg ggtcggtcac gagcgcgggt cacgtttcat
     3841 cggtggatgg agcaccggtg gctactgcgc tgccaatttg tcgactaaat atcccagggc
     3901 tttcaatgcc gggttctctt tgggtgggta ctaccatccc atgttcgaga atccgcgcat
     3961 cgccaacatg gcccgacccc ttatggccaa cagctcggtg gtgcgtaggg tccaggaacg
     4021 caagattgag cgcagcgtgc ggtttctgtc cgtgctcaac cccaacgatt tgcagagctg
     4081 ggggcccggt cgtgtaccgg tggtttcgaa cgggcaagtc ggcccggacg gaggccagtt
     4141 ttaccatgtc gccaaaggca tgaagcagtt cacctttatc ttgctcacgg gtggcggaca
     4201 ccgcgtcagt gtgtacacac cgtatatcga gcagtcatta cagtggcttg gccagttcgg
     4261 gctgtaattg ccgccgggag tcatgatcga gtctgggacg gtagtctgtc ctggtaagga
     4321 actagcgcgc tgaaggacaa ccgtgttcga cactctccaa gaccgcctcg catcaacctt
     4381 caagggattg cgtggtaagg ggcgtctcac tgatgccgat atcgatgcca cgactcgcca
     4441 gattcgcatc gccctgcttg aggctgacgt caacttgtcg gtcgtcaagg aattcgtggc
     4501 ggccattaaa gagcgttgcc acggcgagga gctttctaaa gcgctcaatc cgacccaaca
     4561 gatcgtcaag attgtcaacg aggaactcgt cgagatcctc ggagggcaga cccgtacggt
     4621 tcggtttgcg aagactcccc cgacgatcgt catgcttgcc ggcttgcaag gtgctggcaa
     4681 gacgaccctg gctgggaagt tggctcggtg gttcaaggaa gagggccact ccccgttgtt
     4741 ggccgcctgc gacctccagc ggcccaatgc cgtcactcag ttgcaggtgg tcggagaacg
     4801 tgccggggtg cacgtcttcg ctcctgaacc tggcaacgga gttggggatc ccgtccaggt
     4861 agcccgtgat gccgtcgcag aggccgagca caagctgtac gacgtcgtca tcatcgacac
     4921 cgctggtcgt ctgggcgtcg acgccgagat gatggctcaa gcggctgaca tcaagactgc
     4981 taccgaccct gacgagaccc tcttcgtcgt tgacgccatg attggtcagg acgcggtcaa
     5041 cactgcggtg gccttccagg agggagtcgg attcgacggc gttgtcctga ccaaacttga
     5101 cggcgacgct cgcggcggcg cagctctgtc cattgctcgt gtggtcggca agccgatcat
     5161 gtttgcttcc tcgggtgagg gtctcaagga cttcgacgtt ttccatcccg accggatggc
     5221 ctcgcgcatc ctcgatatgg gtgacatgct cacccttatc gagcaagccg agaaagcttt
     5281 cgatcaggag caatctcagg cggctgcggc caagctcatg gcaggcaagg gggagttcgg
     5341 tctcgatgac ttcctcggtc tcatgcgtca aatgcgtcgc atgggcccga tgtccaagat
     5401 catgggcatg ctccccggcg tcggccagat gaaaggccag attgagaaca tcgatgagcg
     5461 ggagattgac cgcattgagg ccatcatctg cgcgatgact ccggccgagc gtgctgacgt
     5521 gtcgatcctc aacgggtcac gtcgtgcccg tattgctaac gggtctggcg tggaagttcg
     5581 tgacgtcaac aacctggtca atcgatttgt tgacgctcgg aagatgatga gccagatggg
     5641 ccagatgatg ggtcctggtg ctggccgcat gatggggtcc atggctaagc gcggttccaa
     5701 acagtcgaag aagaagcaga agaaccgtaa gggctctggt aatcccgcca agcgtgctgc
     5761 tcaggctcgt caagctgcaa agaaaccgca gcggagcagc ggtgaggcgt tcgggttgca
     5821 gggccagcag caacccagtc aggaagatct gcagaaggca atgagtgaat tcaagatgcc
     5881 gccgtcaatg cagcagatgt tcaaccaaac gaacaagaga ccgcgttgaa ccagcgtcgg
     5941 tgatgtgtga agagatcgcg agtttgacat tacttctccc cgcgacttcg tgacacgatg
     6001 gggccatgac cgaggacacc cagccgttgt tccacactca cacccacgac ggatggactc
     6061 atacccatat ggcccgtgag gcccaaaccg ctcctgatga agacttgcgt atccggggcg
     6121 tcgtgctacc tgacggggaa gaacgtgaac tatgggttca cgacggagtc ctcgtggaag
     6181 ggccgctctc gggggctcga actttggctg acggctgttg gatcattccc ggtctagttg
     6241 acgcccataa ccacattggc ctcgatgctc atggtgccgt tggcacggag actgccgacg
     6301 agcaggcccg gaccgaggcg aagacgggca cccttctcat ccgcgatgct ggatcgccga
     6361 gtgataccca ttggatcgac gaccgcgacg accttccgcg ggtcattcgt gccggacgcc
     6421 acatcgcccg ccctaagcgt tacatccgta actacgcagc tgaggtagat ccggaaaatc
     6481 tcgttgccga ggtcgatcgt caggctcgat ccggtgatgg ttgggtcaag cttgtcggtg
     6541 actggattga tcgcgacgag ggggatctcg ctccgttgtg gcccgcagat atcgcccagg
     6601 ccgccatcga tcgtgctcat gagcttggtg cccgtgttac tgcgcactgt ttttccgagg
     6661 aagctcccgc acagctcgtt gatgccggta ttgactgtat tgagcacggc actgggctta
     6721 ccgacgagac aatcgccact atggctgagc gcgaggtcgg gcttgtcccg actttgatca
     6781 atatcgagac cttcccgtcc atcgccgctc aggccgacgg caagttccca aaatatgccg
     6841 cacatatgcg tcacctccat actcaccgtc atgaaacgat cgccaaggct tgggatgccg
     6901 gagtgccgat ttatgccggt accgacgctg gcggcactat caagcacggc ctcattgcct
     6961 ccgaggttcg gttgttggct gccgtagggg gagcggagat ggcattggga gcagcgtcct
     7021 ggcgggctcg cgcgtggttg ggcggtgagc agctgggtat tggcgattcc gctgacctcc
     7081 tcgtccttga ccgtgacccg agggttgacg ttggggtgct ggagtctccc acctacatcg
     7141 tgctgagggg acgagtagtc atcaggtgaa gtccgtcccg gctcgcgtca tctgcctatc
     7201 tgtggcacaa tgtcgagagc ttctgtccgt tcggtgccct ctcttatcgg cggatagttc
     7261 cacccgagtt cgggggcgat gtccccacgt cgtgtccgtg ctcacccgta acttcccggg
     7321 tttcgtcccg ggcgtctcac tacaggagtt accacacacg tggctaccaa aattcgtctg
     7381 aagcgtctcg gcaagatccg taccccgcac taccgtgtcg tcgtcatgga ctcgcgcgct
     7441 aagcgtgacg gtcgtgctat tgaggaaatc ggccagtacc atcccaaggc cgatccgtcg
     7501 gtcattgtga tcgactctga gcgcgtgcag tactggctcg gcgtcggtgc ccagccgact
     7561 gaagctgttg ttgctttgct gaagcgcacc ggtgattggc agaagttcac cggcgatact
     7621 tcgccgtctg gtgtcaaacc gcagcccgag cgtcccaaca aggatgatct gttcaacgct
     7681 gccctggctg aggccgacga ggccccgcgt gaggccatca ccaagaagtc cgaaggggca
     7741 gctgctgacg aggcttccga gtcggcggct ggagacaaca gtggcgagaa ggctgaggcc
     7801 tgatcgtgct agccgacgcc ctggaacacc tcgtctctgg catcgtcgcc aatcctgacg
     7861 acgtccgggt ccgggagaag gacctgcgac gcggccggat gcttgaggtg cgcgtcaatc
     7921 cttccgacat tggtaaggtc atcggtcgtc agggtcgtac ggcctcttcg ttgcgcacgg
     7981 ttattggtgc gttggccggt gacgagcaga tcaggatcga cttcgttgat gttgatcgac
     8041 gcgggtcggg acggcattcc gaccaccgtg gccatcgtca ctgaatcgcc agtcctttga
     8101 caatatgggc cgtggttccg ctctggcggg gctgcggccc atgtgctgtg tctggcatct
     8161 tgtctaatct catcattccc caggagtcac agtggaagag tcggcaacgg tggaggtcgt
     8221 cgtcggacga gtaggtcgtg cccatggtct gcgaggtgac gtcgtcgttg aggtgcgtac
     8281 ggacgaacca gatgcgaggt ttggagtagg tgccacggtg cagattgagg ggtccagacg
     8341 tgatctgacg gttgtacggt cccgctgggc caagggctgc cttatcgtcg cttttgacga
     8401 agtgaaagat cgtcaggggg cagaggagct acgcggatcg gttctcgtcg ttgacgttga
     8461 gcccaacgat gaccccgatg accccgatga attctgggat cgccggttgc gtgggctgac
     8521 agtggttgat gaatcaggta aaagccgcgg ggctgtcaaa gatgtgcttc atatgccagc
     8581 ccaagatgtg ctcgtgatcg acgtaagtgg ggaggaacat ctggttcctt tcgtccacca
     8641 actcgtccct actgtcgatg tggcgtccgg gcggatcgtc gtcagtggca ttcctggctt
     8701 gctcgattcg aacgctgaag aggcgaggtg acgatgaggc tggactacct gtcaattttt
     8761 ccggcgtact ttgatgtcct cgacatatct ttgctgggta aggcggcagt caacggtctg
     8821 gtggaggtcc acgcccacga cttgcgcgac tggacccacg atcgccatcg caccgtggac
     8881 gacaccccgt gtggcggagg cgcgggcatg gtcatgaagc ctgacccttg gggggaagct
     8941 ttcgacgaga tcattggcac tgagccggac tcgtcggttc atgtgatttt ccctagcccg
     9001 tcaggtgcgc catttaccca gtctgctgct caagagttgt cgtcggcggt gcggatcgtg
     9061 ttctgttgcg gacggtacga ggggatcgac caccgcgtga tcgactatgc gcggtcgatg
     9121 tggactgttc atgaggtgag cctgggagac tacgtgctta atgggggaga agtagcggct
     9181 ctggctatca ctgaggccgt ggttcggctg gtgcccgggt tcatgggtaa cccggagtct
     9241 ctagcggagg agtcgttctc ggccgggcaa gacggcttgc tggagtatcc gctgttcacc
     9301 cggccggtct catggcgtgg cctcgatgtc cccgaggttc tcatgagtgg tcatcatggt
     9361 cgaattgcga agtggcgccg tgatgagtca gtccgcctga cgtgtgagcg gcgtcctgat
     9421 ctgacggatt ccgacttcgg tgttccccat tgaagcgtct ctaatcgaca aaattcgaac
     9481 cgaaaatgtt gcgataatca agagtaaaac ccttagtgaa ccaagggtcg agggaagttt
     9541 tcgaaaacac agggggtggg ggcgcaaaag ggctggtaat tggctagtct ttggtccgtg
     9601 gcgactacaa cacttactac tcatcagaga gcggtgcgat caactgtcgc ggcgaaggcc
     9661 ctcatggccg tcaccgggct gatcttaatc ctcttcctgc tcatgcacat gtttggcaac
     9721 ttgaagctgc tcgctagtaa cgaggaattc aatcgttacg ccggttttct tcgcacgatt
     9781 ctcaacccga tcctgccggg tgaatccttc ttgtggattt tccggatctt catgttgctg
     9841 gcgatcgtgc tgcacatttg gtcggcgatt cgcgttaaca agcagcgcaa cattggaacc
     9901 ggtggcgctg gccgttactc ggttaagaag aacctctcgc cggagaatac ctatgctgcc
     9961 cgcacgatgt tctggggtgg ctggatcatc ttcctattcc tcatcctcca cctgctgcag
    10021 ttcaccatta gccctgactt gctcaataac ccgcccaccg atgcagctgg acgcgcaggg
    10081 atggtactta cggccttcag ccactggtgg ttcgtgctca tttacctcat cgccatgatc
    10141 gcggtgtgca tgcacgtctc ccacggtttc tggagtgcct ttgcgaccct cggcgtcaac
    10201 gtctctggta ccgctcgcgc tgtgctgcgc gtgtgttcct ggatcgtcgc catcgtgatc
    10261 ttcgtgggct tcatgactcc tccattcctg gtcctgttcg gggtgatctc ctgatgactg
    10321 caactgctgt atccaataac aacgccgctc tcgccgacca gtactggacg accggcgacg
    10381 aaatccacga cacgaaggcc aaccatgacc ttccgatcga gaagatctgg actgatcgcc
    10441 agttcacctc gcgtctggtc aacccggcta accgtcgcaa gatgacggtc atcattgttg
    10501 gtaccggtct agctggtggc gctgccgccg caactctcgg tgaggccggt taccgcgtcg
    10561 agaacttctg ctaccaggac tctccgcgtc gcgctcactc gatcgcggcc cagggcggaa
    10621 ttaacgccgc gaagaactac aagaatgacg gtgattcgat ctaccgcctg ttctacgaca
    10681 ccgtcaaagg tggcgattac cgctcccgcg agacgaacgt ttaccggctc gccgcggtca
    10741 gcgcgaacat catcgaccag tgtgtcgccc agggcgttcc gttcgcccgt gagtacggtg
    10801 gcctgctcga caaccgttcc ttcggtggcg tccaggtgca gcgcaccttc tacgctcgcg
    10861 gccagacggg ccagcagctg ctcatcggcg cctaccaagc cctcgagcgg caggttcacg
    10921 ccggcaccgt gcatatgcac acccgtcacg agatggtcga gctcatcgtc gccgacgggc
    10981 gagctcgcgg catcgtgact cgtgacatgg ttaccggcaa gatcgaagag tggtttggtg
    11041 acgccgtcgt cctggctacc ggtggttacg gcaacgtctt cttcctgtcg acgaacgcca
    11101 tgggctgcaa tgccaccgcc tcgtggcgtg cccaccgtaa gggcgcttac ttcggcaacc
    11161 cctgctacac ccagatccac ccgacctgca tcccggtgca tggtgaaaac cagtcgaagc
    11221 tgactctgat gtcggagtcg ctgcgtaacg acggccgtat ctgggtgccc aagcgcgcgg
    11281 aagattgtga aaaggatcct cgcgacatcc ccgaggaaga tcgcgactac tacttggagc
    11341 gcatctaccc gtccttcggc aacctggttc ctcgtgacat tgcatcccgt caagccaagt
    11401 accgctgtga cgagggtcgt ggtgtcggtc cgaaggttcg tgaggtcgat tctgacggca
    11461 ccgagcacat gcgtgcccgt ggtgtgtacc tcgacttctc cgaggccatc cagcgtatgg
    11521 gtaaggatgc cgtggaaaag aagtacggca acctcttcga catgtaccag cggattaccg
    11581 acgagaaccc gtatgaggtt cccatgcgta tctaccctgc ggtgcactac acgatgggtg
    11641 gcctgtgggt cgactatgac ctgcagtcga ccattccggg tctgtttgtc tgtggtgagg
    11701 ccaacttctc cgatcacggc gctaaccggc tcggtgcttc ggccctgatg cagggtctgg
    11761 ctgatggcta ctgggtgctg cccaacacca tcaccgatta cctggcggac tctccgaagt
    11821 tcggcatggt cgatgagaag catccggccg cggttgaagc ccgtcaggct gtcgagagcc
    11881 gtatcaacaa gctgctaacg attaatggaa cccgtaccgt cgactcgatc cacaaggaac
    11941 ttggccacat catgtgggag tactgcggta tggagcgcag cgaggccggc ctcattaagg
    12001 ctattggtct catccgcaat ctgcgcaacg agttctggac caacgttaag gtcaccggcg
    12061 tcaacgagga gctcaatcag accctcgagc gcgctggtcg gctcgccgac ttcttggagc
    12121 tcggtgaact gatgtgcatc gacgctctac accgtcgcga gtcttgtggt ggtcacttcc
    12181 gcgctgagtc tcagaccgaa gagggcgagg ccatgcgtca cgacgacgag tatcagtacg
    12241 tcgctgcctg ggagtggact ggcgaaggcc acaagccgac cctgcacaag gagccgctgg
    12301 tctacaagtc catccaggtc aagcagagga gctacaagtg aagatcaacc tgcgaatctg
    12361 gcgtcagcgc aattccaagg atcagggccg cctcgtcgag tacaccctgg acggtgtttc
    12421 cggtgatatg tccttccttg agatgttgga catgctcaac gagaacctca ccgctcaggg
    12481 tgaagagccc gtcgcatttg actcggactg ccgcgagggt atttgcggtc agtgcggcat
    12541 cgtcatcaat ggtgtgccgc acggtggtat gggtgttgcc cagccggtgc gtaccactac
    12601 gtgtcagctg cacatgcgct ccttcgccga tggctcgacc atcacgatcg agccatggaa
    12661 gtcaggtgcc ttcccgattc tgcgtgacct tatcgtggat cgctcggccc ttgaccgtgt
    12721 catccaggct ggcggctatg tctcggtgaa caccggtgct gccccggacg ctcacgctgt
    12781 tcaggtcaac aagaagcgct ctgaccgctc cttcgacgcc gctacctgca tcggttgtgg
    12841 cgcctgcgtg gcggcctgcc cgaacggctc ctcgatgctg tttacttctg cgaagatcac
    12901 tcacctggcc atgcttccgc agggtcagcc ggagcggatg cgtcgtgtta aggctatggc
    12961 tgcgcagaac gacgctgaag gattcggtgg ctgcaccaac attggtgagt gcgcctcggt
    13021 gtgcccgaaa ggtattccgc tggagtccat cagccagctc aaccgcgacc tcattgcgtc
    13081 gctgttcaag cacgacggca aggacgactg agtcctgact cgtgtggtcg attactcggg
    13141 ctccgacacc tcgcggtgtc ggagcccggt tatgttgtgg agcactgcct gttggcgggc
    13201 acgagtgatg gtggatttga tgccagagcc atgggtatgg aaaaataccg cggtgttgtc
    13261 cgtgtccggc tcctgccaca gggggacagt ccggcgctcg gggaacgaaa tctttgtgaa
    13321 cacgagcacc aggtgacctg tggcaccggc gaggaaacac tatgagcaac atcatcgacg
    13381 agatcgacaa ggcctcgatg cgcgacgaca tccccgagtt ccgtcctggc gactcggtga
    13441 aggtccacgt caaggttgtt gagggtagcc gtacccgtgt gcaggtcttc tccgggatcg
    13501 tcatctcgcg taccggtggt ggcgtccagg agtcctttac cgtccgcaag ctgagcttcg
    13561 ggaccggtgt tgagcgtacc ttcccgctgc attccccgat cattgacaag atcgaggttg
    13621 atcgccacgg tgcggtccgt cgcgccaagc tgtactacct gcgcggccgg cgtggcaagg
    13681 cggccaagat taaggagagg ggctcagctc gctgacgtcg tcttaacagc aacggggttt
    13741 cgttacggcg aagccccgtt tttgtatggt tccactcaca tctggggtag gcgcgtcatg
    13801 atgcagcttt tttctgtgcg ttggttacac tgcaaggtgg cacccgacgg gaagttccca
    13861 caggggatga gggagaggtt ttgccgtggc ggatgactac cgggcgaggc gggctgcaaa
    13921 cggcgacacc agggactctg acgatgcaac agcacgtggg gaacaggcgt ctgggtggca
    13981 gcgctttcgg tcgggggcga tcgaagttgt tctcatcgtc gttggtgccc tcatcatctc
    14041 agctgtgctg cgtggtttcg tcgctcagat gtttgtcatc ccgtcgaagt ctatgcaaaa
    14101 caccttgcag gtgggcgacc gcgtgatcgc ggtgaaagcc gccgattttc atcggggcga
    14161 cgtcgtcgtg ttcaaagaca ccgaacattg gctacctgct gcccaggatc gccgctctgt
    14221 tccaggacag atcctcgaat tcgtcgggtt gttgcctaac aagagctcga actacctcat
    14281 taagcgagtg atcggcatgc ctggggacac cgttgcctgc tgcaacgtca acggccaggt
    14341 gaccgtcaac ggtaaggcgc ttgacgagcg gtcatacctg tactccgaaa atggtgaaat
    14401 ggttaaaccc tcggcgatgg aattccgggt cactgttcct cgggggcgga tgttcgtctt
    14461 gggggaccat cgcaatgcct cgggtgactc gcgctatcac ctccaagacc ttgatccggg
    14521 tgagtatacg ggcgctcctg cgtttgtgcc gctcgatgac gtcgttgggc cggcaaaggc
    14581 cattctcatg cctctcaatc gcattgaggg actggggact cctgacattt tccgaggaat
    14641 cccggatagg tcgtcgtcag ctccaggcaa ggcgcgcatc tgcgtcggta acgcgtgctg
    14701 ccctaagtga cggattccat gtcggtgcga gtcgggtcgg ggccgatggg ccatgaacgg
    14761 gccctagcga gggccggact cggccccgtg gccggatgcg acgaggcggg gcggggcgcg
    14821 tgtgcagggc cattggtagc cgcagctgtc attcttgatg atcgcagatc cggcaggatt
    14881 gcggggctag cagattccaa gacactatct gcggccaaga gagaggccct gtttaacgtc
    14941 atcatggata aagctttggc agtgtcgtgg gtaggtgtag aagccgacga atgcgatcgg
    15001 ttggggatgc aggaggcaga tatcagcggc ttaaggcgtg ccgtggtgag gctgggagtt
    15061 gaaccgggat acgtgctgtc ggacggtttc ccggtcgacg gactcacggt tcccgatctg
    15121 ggaatgtgga agggcgattc agtgtgtgcg tgtgtggcag ctgcctccat cgtggccaaa
    15181 gtggccaggg atcgcatcat gatcgctatg gacgccgaga ttcctggtta cgattttgcg
    15241 gtgcacaagg ggtacgcgac agccttacac cagcgccgtc tgaaggagtt aggaccgtct
    15301 cgtcaacacc ggatgagcta cgccaatgtg cgacgagcgg ctaggcttca ttcatcatga
    15361 gtgccgaaga tctggaacag tacgagaatc ggatggagtt ggagctctac cgcgagtaca
    15421 aggacgtcgt cgggatcttc aaatatgccg tagaaaccga gagacggttc tatttgtgta
    15481 acgtcgtcga tctcaaggtt cgcaccgagg ggggcgacgt ctactacgag gtgtctatgg
    15541 cggatgcctg ggtgtgggac atgtaccggc catctaggtt cgtcaagagc gccaagatcc
    15601 ttaccttccg cgatgtatcc attgaggaga tcgtgcatgc tgactttgac gaggtgccgt
    15661 ctaagtaacg ccaggctcgc attccttgac gttacgtgtc catgtccaat cctgtgacgt
    15721 gagtgtggac atcgtgtggt cttgaccggt ttccactccg agtcggaatc gtctgtagac
    15781 ctcgtaggtc atcgtactta tcggtggcag aggtttcgtt accggcgtgg ggctttgtgg
    15841 ataacttatg gtgcttctga tcccgaaaca ttgatctgtg gataactgaa taatcaggtg
    15901 ttctccgacg ataactgttg tcggaggtgg tgaatgatga cacctaagcc attgtcggca
    15961 gagctgacga ccccgcgtgg agctgcgttg cgtgggcgtc gtggttgcag acccgcgttc
    16021 ggtgcgtggg gcgaggatct tgccgctcag tatgtggagt ccctgggatg gacaatcatc
    16081 gcgcgtaact ggacgtgtga tgtgggagag attgacctca tcgcgcgtga cgaccagacc
    16141 gttgtcttta tcgaggtgaa ggccaggtta ggcactggct tcggcgaccc gctggaatct
    16201 attacgacgg cgaaggtccg taagcttcac gaactagcac tggcgtggtt ggttaaccag
    16261 gacgacgggg tccactcggt gcggattgac gccatcggtg tcatggtgcg cccgggcgcc
    16321 gagccaactg tcacacatgt gcgaggtatc cggtgaccgg cgcaagtgcg tggtcggtcg
    16381 cgttggtagg gatggaaggc tccatggttg aggtggaagc cgcaatttcg tccggactgc
    16441 cgcgtaccgt gcttgtcggt ctgccagacg cggccctcca cgaggcccgg gaccgatgtc
    16501 gggccgctgt ctgcgcgacg gggttgtcgt ggcctagcaa tgtgttgacg atcaatctca
    16561 cgccagctgg cctaccaaag gctgggacgc attttgatct ggccattgct gcagcgacgc
    16621 tggctgctga tggaaaggtc ccacaggctc tcttgggatc gacggttctg attggagaac
    16681 ttgggctgga cggccgagta cggcctgtgc gcggcgtgct gcccgcgctg ctagcggcgc
    16741 gggaggctgg gtttgagcgg gcggtagtac cggctagtca gagtgatgag gccagtctcg
    16801 tcgagggatt gatgatctgg ccagtcggcc atctgggtga cgttgtcgac gtgttacatg
    16861 gtcgtccagt ggtgcctcct gagggcccca ttgtggggtc tcccgacacc gatccgggga
    16921 taggagacct aacggaggtt atcggccagc acgaggcgcg ccgagccctt gaagtagcgg
    16981 cagcggggcg tcaccacatt ctgctacgtg gcgctcctgg ttgtgggaaa tctatgttgg
    17041 cacgacggtt acctgggatt cttccccgac ttgatcaccg tgacgccctc gaagtcaccg
    17101 cactgcattc cttggccgga cgagggagcg ggcgtctcat gacgaggccc ccactggctc
    17161 aaccccatca ttcggtgtcg atggcggcca tggtcggtgg gggagtacgt attgcccaac
    17221 ccggcgcgat ctcgctagcg catcgagggg tgttgtttct cgacgaggct ccggagtttg
    17281 cgccaaaggt gttggactcg ctgcgtggac cgctggagac gggggaaatc gttattggac
    17341 gttctcaggc acacacgacg ttcccggctc ggtttcagct tgttatggcg ctcaatccgt
    17401 gcccgtgtgg gctggccgat gacccatcgg gacggtgcac gtgcactccg caacaggttc
    17461 gccggtattc aggtcggctt tcgggcccga tcctagacag agtggacgtc acagtcagga
    17521 tgcgaccgct gacgtcggcg catctgcttg atgcgtcagc tctgcccgcg ggggaatcta
    17581 gttcagcggt gcacgagcgg gtcgcgcaag cccgtgagcg tgctgccgcc cggtggcggg
    17641 gagttccctg gcgatgcaac gccgaggttc caggaaaagt cttacggcag atgttgccgg
    17701 ccaatgacgc cactcgaatc atcgaagatg ctctgacaac cggacggctc acggcgcgag
    17761 gcgtcgacaa agtgctgcga atcgcgtgga cggtggccga cctcgagggc aaggacgagg
    17821 ttgacaaagc gtgtgtggcg gaggccatgg gaatgcgacg agaaagattg cgatgacgtg
    17881 gacgagcgag agattggcgc gggccgctct gacagctgct gccgagccgg gggtgatggc
    17941 gaaacgacta gttgagatga ccgctgaaga gctgtggcag cacatgctta ccgattctgg
    18001 cgaacgatgg cacaaacgag ctaaatcgct cgacgtcgat caactcgtgg agcggtcgga
    18061 aaaggctgcg atgaggttcc tcattccagg ggatgaggaa tggcccacgg gtctcgacag
    18121 cctcgcgcgg gtggggaaat ctggaatggg tggggcacct gtggggctgt gggttacggg
    18181 gcctgctcac ctcgctgata tctctcagcg ggcggtggcc attgtgggat gccggtctgc
    18241 tagcagctat ggtcaagacg ttgccgtaga aatggcctac cgcttagtac ggggacactg
    18301 tgacggaacg ggaagccata ctgttatatc tggcggcgcg ttcggtatcg atgtggcggc
    18361 tcaccgtggg gcattgtccg ctcgcggaaa cacggttagc gtcctcgcat gtggacttga
    18421 caccctttat ccccgtggca acagcgcagt gctggaacag atcgcgggaa caggtgccct
    18481 cgtttcagag ctaccgctgg gtcgtcaccc gacgcgacct ggattcctcg cccgaaaccg
    18541 gctcatcgcg gcactgacga ctggcacggt cgttgtggaa gctggatggc ggtcgggagc
    18601 gatcaatacc gcgtcgtggg ccaacgcatt aggaaatgcc gtcatggcag tccccgggcc
    18661 agtgacctcg agtcggtcga cggggacgaa caaactgatc cgtgatggtg aggcgatctt
    18721 ggtgcgcgat gctgacgacg tcagagggat tgttggggag ctcgccccag aaccggagag
    18781 accagcaggg cgcagcttgc cgactgacat cctggatgcc attgagctgg ctgttcatga
    18841 ggcactcccc gctcatggat cgtgcgggct agatgagtta gcggttttgg ctggagttcc
    18901 cgttgctcag tgttcggctg cgctaagcgt cctcgaacaa ctcggcatgg cggcttgttg
    18961 cctcgacggc acctggtcgg tcacgctggc aagggagcgg aggtgacact ctctagattg
    19021 agcaggaagc gcttgaggcg aggaccaccg agatagcctc ctagctggcc gttactgcgt
    19081 agcacgcggt ggcacggaat gaggatgggc agagggtttg ttgcacaggc gtggccgacg
    19141 gcgcgtgacg cattcggccg tccaatgatg ctcgcaagtt ggcggtagct gacagtttgc
    19201 ccataaggca ctgtttgcaa cccggttagt acagtgcgtt ggaagtccgt cgtcgcagaa
    19261 agatccagcg ctacgtcgaa tgaggtccgc gatcctgaca agtactcggt gatctgtgca
    19321 atggcacaag agatgatgtc accgctgcgg cgagcatgtg atgtcgaaag tggcggcggt
    19381 gatggatctg tcttgacgaa gacgagccga ctgagcccat gagcggtagc tgttacttct
    19441 aactcgccaa tggcggtgtc aaagcggtgc tgggactgtg ctgtcatagc aggaagcggg
    19501 ccgggcacct gatgcccggc ccgacattat caacccttta gcttgtcagc cgcagcctgg
    19561 acattgtgct tgaggtcatt cgccttgtct ttgacgtcct cgaccttctg agctaccttg
    19621 ccactggcct tctgatcggc gcccgcgctc ttgagatcgc tgtcatcggt gaggccaccg
    19681 atcttctcct tagcagcgcc gacggcttcg tcgctcttgc tgttgatctt atcactcagg
    19741 cccacaagtc actcctttcg ttggtcccag ggccgcaggt cagcccaggg acatacccat
    19801 attttactcg gctacccaag ttcgactagg ggtttgtatc caaaggattg tgggattgtc
    19861 ggggattcaa agagcgaggt caagcgatga gggacagcag aggttgcgtc ccctcgactc
    19921 atcgcgggac gcaacctcag gcggaatcag gacgggttag ctcacttgtt gtgggcgtcg
    19981 atccagtcga tggcggtctt gatgacctga tccttagtgg gctcattgaa gatctcatgc
    20041 atgaggccat gccactggat gatcttcttg tccttcgagg tgatggcgtt gtaccagttg
    20101 acatcgaagt agctgggcac caggccgtcg ttctcgccat gcatgatcaa ggttggagcc
    20161 ttgaaatcgt gggcattcat gacgttgtaa gcctcggcga cacccatctg ctcgacgagt
    20221 ccgagacgca tgtaatggtt gtacagcggg tcgcggtgcc agtggtcgaa gcggactgcc
    20281 ggatcggaac acaggccgta tggcgggtag ccgggcagaa tgatgtcagc agacaacgga
    20341 cccgaaggca tccgaatcgc cttgggattt ttgacgaagt ccttcactaa gcgcccgttg
    20401 aagctggtca gctgggcatc gggagaagct ggctgatctg gggcagggcg tgacgggcaa
    20461 agaaattgag attgtcgggg gtgatggtgg tggctccctc ggtgtcggga ccatccacgt
    20521 tgacgatggt gccgccgccg gaggacacaa tgccgtcaac agttcctgga tacatgattc
    20581 cgtaggactg tatgtacggc gattccaccc attgagtggc ccagcaggaa caccttctta
    20641 ccggtatttt ccttgtgcgc ggtaccgact acctgatgga tgtcggactc gatgttccac
    20701 cagtcgtcga actggccgcg cgggatagcg ttgttgatgt acggggctgc gctacgccca
    20761 tggccacgat tgtcgaagcg gtagacgctg tagccagcgt tggtaaggct cttagttagg
    20821 tactcgtagt cggaggagtt ctccataagc ccgtgcacca ggacgacagc tcccttggcg
    20881 ttggggacga tgtccttgcg gtagaagagc tgggttccca gcttatcggt cgtcttgaag
    20941 tagccggtct ccttgtggac ctggttgata gcgggtgccg ctgcagccgg ctgggaactg
    21001 gtgccggtgt tggccagggc cggagttgcc atggttacgc cggtcaccgc catggtactg
    21061 gcaaccgcca atgcgctgag tttgcgtggg aatgacat
//
