LOCUS       c00008_NZ_FMXR..       25152 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FMXR01000006.1 Eubacterium oxidoreducens strain DSM 3217, whole
            genome shotgun sequence.
ACCESSION   NZ_FMXR01000006
VERSION     NZ_FMXR01000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:17:33
            Original ID  :: NZ_FMXR01000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 152759
            Orig. end    :: 177911
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25152
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[162759:167911]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15152
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..25152
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25152
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(789..2921)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_145"
                     /sec_met_domain="Peptidase_U32 (E-value: 5.8e-77, bitscore:
                     252.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELLAPAGSYEMMLAVFEAGADAVYLAGERFGARAYAKNFNEEE
                     LLRALDYAHLHNKKIYLTVNTLLKNREIADELYTYLHPYVKNGLDALLVQDWGVFDFVK
                     NVFPNLQLHASTQMCITSTKGAKFLEQQGASRIVLSRELSLQEISNIHKNVKAELEVFA
                     HGALCYSYSGKCLLSSLIGGRSGNRGRCAQPCRLSYNLDGVSHDAEYLLSLKDLSTIDI
                     LPQMLEAGTHSFKIEGRMKQKEYAYQVVSLYRKYLDIALEQVSDFKVAPKDREMLLNAG
                     NRCGFTKGYLTGCVDSQMVTFVLPSHKKKTKEQPSLEFVEQKIPVRISMEFRIDQPAIM
                     TLTAGDKSVCVCGETVLAASSRPLTKEEVIKKGAAFGTTPFEVTDLEIELDDNVFYSAK
                     SLKTLRRQAVQELMEELLAKPREVFAETVYHKNLSSLENKKPYMAVKVSTIEQLEDSLK
                     RSFVDAIYVDFDLLIGGEKLLDILSNTDKKVALCLPYVIKEQTSADIKKILTKYSHLSN
                     INYIANDYDGIGMLEELGISKDRIILDAGLYTFSDYAMQGFWKAGYRTFTVPYELNEKE
                     LLHRENSHSEMVVYGYLPVMQSAQCLRKNTGQCTKDSAIVFLTDRKKQKMMVKPHCELC
                     YNTIYNSQPLCLIQHANKIKSMNFKGYRLEFVTESKKQVMRILDYYEQEFIKKERWNPD
                     IMLDSYTNGHFKRGVE"
     CDS             complement(2987..3424)
                     /locus_tag="ctg8_146"
                     /transl_table=11
                     /translation="MATKSDAEVIIGGKIYTLSGYENPEYLQKVAAYLNQKMNELKSLE
                     GYQHLSTDLKNVLLNINIVDDYFKAKETADRMEKELQEKDRELYDANHELVSAKMNEET
                     LSEALKDSESKNRELLMNKAKLETTLEDALLGTEEKEETKS"
     CDS             complement(3496..4494)
                     /locus_tag="ctg8_147"
                     /transl_table=11
                     /translation="LEKRIISTQLNKEEQRVENSLRPQQLNDYIGQKKIKENMSIYMQA
                     AKQRGESLDHVLFYGPPGLGKTTLACIIANEMGVNIKTTSGPAIAKPGEMAAILNKLEE
                     GDVLFVDEIHRLNKQVEELLYPAMEDYCIDIMVGEGASARAIRVELPRFTLVGATTRAG
                     LLSAPLRDRFGVVMHMEYYTTDELTQIIKNSAQRLEVEIAQDGAEEMARRSRGTPRLAN
                     RLLKRVRDYAQVKYDGVITKEVANYALDILGVDKEGLDKTDRNILTTIMHHFAGGPVGL
                     DTLAASLGEDAGTIEDVYEPYLVMNGFINRTPKGRVATPKAYYHFGIDLPT"
     CDS             complement(4496..5092)
                     /locus_tag="ctg8_148"
                     /transl_table=11
                     /translation="MYSYFIGTIADIESDRIIIETNNIGYEIFLAEREIEELGVVGDEV
                     KVFTYLYVREDALILYGFCSKESFKMFKLLISVNGIGPKAALAILSILTPYDLQFAILS
                     EDAKTISKAQGVGTKSAQRAIMELKDKISLEEAFEEKSNAHSAQSENNSAKAQAIAALE
                     SLGFSKSQALKAINSLGDISGYDIEMIIKLALKEL"
     CDS             complement(5107..5616)
                     /locus_tag="ctg8_149"
                     /transl_table=11
                     /translation="MKHNVAFLGVFLALALVFSYVEAMIPFAIAIPGVKLGITNIVIVL
                     ILYLNGPKEALIVSVLRVILAGLLFGNLFSILYSMAGALLSLAIMVFIRHTKQFHVITV
                     SAIGGIVHNLGQLIVAAFVVENYNIMYYFAVLMIAGVVTGIIIGIVGNEMIKRVGHLFW
                     KRQVRT"
     CDS             complement(5626..6039)
                     /locus_tag="ctg8_150"
                     /transl_table=11
                     /translation="MEEYYQPKFRKRDALLIGLVLAFAVCIFVIMHTIGAKSGNLVRIS
                     VDGEIYGEYSLEQDETIYVTSKDTVTNVVIIQDGYVSMEEADCPDQLCVEQGKIHLANE
                     SIICLPNKVVVEILENGDDDSASLDDGVDAIAK"
     CDS             complement(6041..7459)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_151"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-32, bitscore:
                     107.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTINIPTTEPQRQFYFIKEAKKYVDFLSKEKGRALTYFVNTFG
                     CQMNARDSEKIVGILEQIGYKPGDSEESDLVIYNTCTVRENANNKIYGHLGYLSSYKEH
                     NPDMKIALCGCMMQEQSAVDKIKSAHRFVDIIFGTHNIFMIAELIVRSFEEEKMVVEVW
                     DGTDQIVENLPAVRKYPFKSGVNIMYGCNNFCSYCIVPYVRGRERSRKPEDIINEIKQL
                     VADGVVEVMLLGQNVNSYGKNLEHPITFAQLLEQVEQIEGLERIRFMTSHPKDLSDELI
                     MFMKHSKKVCHHFHLPLQSGSTKLLEDMNRHYTKEDYLLLVEKLRKAVPDIAITTDIIV
                     GYPGETEEDFLETMDVVERVKYDSAFTFIYSKRSGTPAAKRDDQITPEVIKNRFDRLLK
                     RVQQLASEKAKALEGKTMDVLVESVNSQNKELVSGRLSNNSIVHFAGNKELIGQIVSVK
                     LVCCKGFYYIGERI"
     CDS             complement(7477..8316)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_152"
                     /sec_met_domain="AA_kinase (E-value: 7.4e-46, bitscore:
                     150.8, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRPCIEKKKRIVVKIGSSSLTHEETGNIYFAKIEKLVRELCDL
                     RNSGIDVCLVSSGAIAVGRQAIGLTNKPSSNSQKQACAAVGQARLMMTYQKVFAEYNQT
                     VAQVLMTKNTMILPNSRQNAHNTFEELFAMGVIPIVNENDTVSTYEMQFGDNDTLSALV
                     ATLVNADLLVLLSDINGMYTDDPRENEYARLIEYVPELNDDVMQMGKDSTGSGVGTGGM
                     HTKLNAAMIATRSGADMIITNSNDLNCLHHLFDNEYTGTLFAKNEQTDFLLEDFLKD"
     CDS             8499..9335
                     /locus_tag="ctg8_153"
                     /transl_table=11
                     /translation="MNTNCHNHQKKIALINDYSGFGRCSIAVALPIISMLKVQCCAVPT
                     AILSNHTGFDSYFFDDYTDNMEAYIQEWDKLNLTFNGICSGFLGSKKQIKIVENFIKKF
                     KTDNTIVLVDPVMGDYGKPYATYTTEMCSAMKELVHYADILTPNLTEACILTDTPYKEH
                     WKQSELKTMTEKLFDMGPQKICITGIPQRSFVANYCYWSKKEPRIIRTHKIGDSRSGTG
                     DVFAAILAADAVNGIEFIDSVKKASRFIKKCIECSTKLNIPLTDGVCFEELLYTLK"
     CDS             9346..9951
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_14"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_154"
                     /sec_met_domain="Fer4_14 (E-value: 2.5e-12, bitscore: 41.1,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEILYKVHNNLYVNLTNKCPCACTFCLRQNMDRIGESNSLWLDH
                     EPSFEEVKAAFEQFNLSAYNEVVFCGFGEPTEALDVLLQTAKFVKNTYKKKIRINTNGL
                     GNLVNNKDITPLFKDLIDTVSISLNTSNADDYHKLVQSKFGDCSFNEMLKFAESCTNYV
                     PNVILTTVETTISKDDEAACQKICDKIGATYRIRPWED"
     CDS             complement(10001..10792)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 29.6; E-value:
                     1.4e-09)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_155"
                     /sec_met_domain="Fer4_9 (E-value: 1.1e-08, bitscore: 29.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.4e-09, bitscore: 29.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-14, bitscore: 48.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.004, bitscore: 11.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITAVIIAAIIVAVVGVVIGFFLGFSSEKFKVEVDPKEEAVLDV
                     LPGNNCGGCGFAGCSGLAAAIAKGEAEISACPVGGDPVAAKIGEIMGVEAQAGDKMVAF
                     VKCAGDCDKAKINYNYYGVESCDMMKFVPGGGPKKCDYGCLGYGECVDACPFDAIHIVN
                     GVAVVDKEECKACKKCITACPQNLIELVPYKAKYRVHCSSKDKGKDVMQSCEVGCIGCK
                     LCEKSCHFDAVHVVDNIAYIDQELCKGCGLCAKKCPKKIIY"
     CDS             complement(10805..11380)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_156"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.4e-60, bitscore:
                     197.6, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDVILLAISAAIVNNVVLSQFLGLCPFIGVSKKIETASGMGGAV
                     IFVITIASLVTSVIDKFILQTFDLVYLRTIVFILVIAALVQFVEMFLRKQMPPLYNSLG
                     VFLPLITTNCAVLGIALTNVQKDYGIGVSVISGFATAIGFMIAIVILAGIREKIEYNDV
                     PTPFKGSAIVLITSGLMAIAFFGWSGVV"
     CDS             complement(11395..12246)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_157"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.2e-69, bitscore:
                     226.6, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKYVERLKNGLLTENPTFVLMLGMCPTLAVTTSAINGLGMGLST
                     TVVLVFSNLIISLLRNIIPNRVRVPAYIVVVATLVTVVQFLLQGFVPSLYSSLGIYIPL
                     IVVNCIILGRAESFASKNGPIISIFDGIGMGIGFTFGLTCIGIVREILGAGQLFGAQIL
                     PLADEATGKAGFTPITIFVLAPGAFLVLGFLVAIMNQVKVVAARKGKPLPSNAGSIEGN
                     GEAERITAEKQKEAEAKKLEAKEKMPQVNAVSEKEAVETKVEEKADNTDKQSTKTADDV
                     DK"
     CDS             complement(12239..12859)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_158"
                     /sec_met_domain="FMN_bind (E-value: 6.8e-19, bitscore:
                     62.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKAVVKDAMILTIITLCAGLLLGFVHEITLEPIAQANYNIQQEA
                     YKAVFADAESFEEEEDFDTTAATKVIASDFPDDEIEGLATALDADGNTIGYVITVTSHA
                     GYGGDITLSMGVTNDGTLNGYSITDISETAGLGMKAKEEAFYSQFENKQVEYFEVTKTG
                     STSDDEINAISGATITSKAVTYAVDAGLAYFNTELTQGGSANE"
     CDS             complement(12852..13808)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_159"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.9e-117,
                     bitscore: 385.3, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSDLFNVSSSPHVRAKVSTNRIMLYVIISLLPATIFGIVNFGARA
                     LLLIVATIIACVLSEWIFEKIVHKKSTISDLSAVVTGLLLALNLPSTLPVYQAVIGGVF
                     AIVVVKMLFGGLGQNFMNPALGARCFLLISFTGSMTSFTYDGVSGATPLAIIKDGGSYD
                     TMSLFLGTHAGTIGETSILCLLIGAIFLLAMGVIDLRIPGTYLITFVVFIILFSGHGLD
                     GNYIVEELCSGGIILGAFFMATDYVTSPITPRGKIVFGICLGCLTGIFRLFGASAEGVS
                     YSIIFANMLVPLIERVTIPNAFGVIKEKKKKEAKANE"
     CDS             complement(13833..15152)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_160"
                     /sec_met_domain="Fer4_9 (E-value: 1.6e-08, bitscore: 28.8,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.7e-14, bitscore: 47.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.2e-51, bitscore:
                     167.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.7e-40, bitscore: 131.2,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00029, bitscore: 15.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLGTFKGGTHPYDGKELSKDQPITDYLPTGDMVYPLSQHIGAPA
                     TPIVAVGDEVLAGQKIAEASGFVSAPIYASVSGKVKAIEPRRVVVGDMVNSIIIENDGQ
                     FNAVEFEEVHDLDSLSKEDIIGKIKEAGVVGMGGAGFPTHVKLSPKEPNKIEYVIANCA
                     ECEPYLTSDYRRMLEEPEKLIEGMKIILRLFDNAKGIFGVEDNKPDCIAKLQELVKDEP
                     RLSVMPLMTKYPQGGERQLIYATTGRAINSKMLPADAGCIVDNVDTIVSIYRAVKLGRP
                     LMHRIVTITGNAVVNPANYNICIGTNYRELVEAAGGFKSTPEKIISGGPMMGFSLFSLD
                     IPTTKTTSALLCFTKDEVAEYETTACINCARCVEVCPEQLVPSRLADFAENHVEDMFEH
                     WNGLECIECGSCSYICPARRSLAQSIKSMKKTVIANKRKK"
     CDS             15329..16417
                     /locus_tag="ctg8_161"
                     /transl_table=11
                     /translation="MKIFQSKKEIPHKIDFFSKHFFNNPLFYDIETTGFSRDFHMIYMI
                     GIGKLVNETIVSTHFLAETKEDEVSIIKSFFDALSDSDLLISYNGKRFDLPFIIARAQK
                     HSLSLPLIFPEELDIYLEAKPLFRLLPTPDQKLKTMEHYLHITRNDKMTGGELITVFQS
                     YLNTHDAESETLLLKHNTEDILNLPELMQLLSIKEILSFEHLSNFNYSIEEFTGANGNP
                     CKELALSYNHSCTITNSFIFYCDQFFIRIDPSKIRIQIPIKTGNMLYFYDNYKDYYYLP
                     EEDRAIHKSVASFLPKELRQKAKASNCYQKYEGDFLPNPNNIFSPSFKQSYKSKDSFLA
                     LDQSKDYLLSHIKKYLQTLLTL"
     CDS             complement(16459..17235)
                     /locus_tag="ctg8_162"
                     /transl_table=11
                     /translation="LANDYEKFKKDIYMMTKIDLSSYKEKQMKRRIDTLIAKNGIKEYD
                     EYVGVIKKDKAKFEEFVNFLTINVSEFYRNPEQWKLLDEEIIPDLIQRFGKNLKVWSAA
                     CSTGDEPYSLVMALSRHLPLNNIRITATDIDKQVIATAKVGLYNEKSIAGVPKDLKEKY
                     FTKIGNSYQISEEIKKRVTFKEHNLLKDPYMSGQHLIVCRNVLIYFTDEAKEEIYKKYN
                     KALVQGGVLFIGSTEQIINYKELNYSREQSFFFRKL"
     CDS             complement(17262..18374)
                     /locus_tag="ctg8_163"
                     /transl_table=11
                     /translation="MSETGNFDEMLEDYDKTIRNGEVVEGVVLEVRPDEIVLNVGAKSD
                     GIIPRNEYTNDSNLDLTTVVSEGDNMTVKVVKVNDGEGQILLSYRRVLAEKGNQRLEEA
                     FNNQEVLTAVVDEVKSGGLSVDVEGARVFIPASLVSNTYEKDLSKYEGQEIEFVITEFN
                     PRRRRIIGDRKQLIIAKRAELQKELLEKIQVGDVIQGTIKNVTDFGAFVDLGGADGLLH
                     ISEMSWGRVDNPKKLFNNGDEVRVYIKDIKDTKIALSMKFPDENPWNDASEKFAVGNVV
                     TGKVARMTDFGAFVELTPGVDALLHVSQIAHEHIEKPSDVLKNGQEIEAKIVDFNEADH
                     KISLSMKALIPQEEKAEEEQASVEEASEEE"
     CDS             complement(18352..19212)
                     /locus_tag="ctg8_164"
                     /transl_table=11
                     /translation="MEVIVAKSAGFCFGVKRAVDSLEKLVETKTDQKIYTYGPIIHNES
                     VIQHFESRGVTVLHSKEELLEIQDGIVVIRSHGVGKEIYELLNYRGIEYCDMTCPFVRK
                     IHDLVAEYERKGCYILIAGDKNHPEVQGILGWCSPDNSQTFQTASEFEKLGIEKDRSTV
                     LVAQTTFNHNKFKNLVEIINKKGYDINVLDTICNATEVRQSEAIQLSKDVDAMLVIGSK
                     NSSNTQKLFEISRVGCPCTYLVQTSTDLDGSIFKGIKSVGITAGASTPKKIIEEVQTNV
                     RNRKF"
     CDS             complement(19216..19878)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_165"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.6e-80,
                     bitscore: 263.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKNIAVDGPAGAGKSTIAKKVAKNLGLIYVDTGAMYRAIGLYML
                     RNNIDVSDEEAVNQACDQISVSIQYVNGEQQVLLNGENVNGFIRKEEVGNMASKTSSYP
                     KVRAMLLDAQKELAQKQNVIMDGRDIGTCVLPDAELKIYLTASVQTRAKRRFDELVEKG
                     VECDITEIEKDIEQRDYQDMNRTIAPLKQAQDAVLVDSSNLTIEQVCETIINLYEER"
     CDS             complement(19895..21139)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_166"
                     /sec_met_domain="HI0933_like (E-value: 2.9e-135, bitscore:
                     445.2, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKVVIIGGGAGGMMAAATCAQNCDVTLIEQNEKLGKKLYITGKG
                     RCNITNNSDVEKHLSMVKRNPKFLYSAFYSFDSSSVMRFFEEHGLKLKTEHGDRVFPVS
                     DHASDVIKTLERAMKEGQVKIKLNEKVTQIKVKNERVCAVVTSKSCYEADAVIISTGGI
                     SYPSCGSDGSGYELVNKLGHTIKECAPSLVGILTKEEWVTELMGLSLKNVKVSFERGKK
                     CLYEEQGEMLFTHKGISGPVVLTASSVLNDELKTGTVDIWIDLKPALDKEQMDKRILRD
                     FQTNINRQFGNSLNKLLPSKLIPVIVRLSGIDPKKKVNEVTKKEREKLVELLKGLRLTS
                     KELGGFSEAIITKGGVSVREVDPSTMESKLVKNLYLCGEMLDLDALTGGYNLQIAWSTG
                     YLATQSVLDKNVIDE"
     CDS             complement(21136..22056)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_167"
                     /sec_met_domain="SIS (E-value: 1e-21, bitscore: 71.3,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNANNLLTRMNEQYASMSKNQKKLAAYITDNYEQAVFFTAAKMGE
                     VVGVSESTVVRFAMSLGYKGYPQFQKSLEEMVRLKLEKTQKMNITTTRTSKKDVLQKVL
                     ASDCDNIKRTLEGLNQSTFDQAVSSILNAEHIYVVGVRACAPLAQFLYFYLQMIFKNVH
                     LVTSSNVTEMFEQMVHLTNKDVVIGISFPRYSMRTLKAMEFANNKSAGVITLTDSVHSP
                     MNLYSSCNLIAKSEMASIVDSMTAPMSVINALIVALTMFRKDEVVKNVEFLEDIWEQYQ
                     IYENDEIDHIDDAFKNKYKHIGELK"
ORIGIN
        1 gacaccaagt cccgctccaa tatattttgg ggatctggtt gccacataca acataacaag
       61 ataagccaca aagaaaataa gtgccgctcc aagatccgta gaaagaacca aaattccaac
      121 atgaatgatt gcaacaattg tagctttcac aacctgcttg aattctgttg attcataaag
      181 catagaagca acaaacatca caaaaattat tttgataaat tcagacggct gcaaggatac
      241 gctgccgaaa tttatcgata actgtgcgcc ataacttgtt gttcccatca ctttaaccgc
      301 tgcaagaaag acgattccga ctccggcata aatccatgtc agttttttga aaaattttac
      361 ctttcgaatc agtagtggaa cgattaatgt aaggacaagt ccaacaacag cgatttcaaa
      421 ttgtctaagc gcagattcaa actccagcct cgtcagcatg ataaatccaa taatcatcag
      481 catgcacata ttattaacaa ccaatctgga tgcctttttg tatatttttg tgtacaaaat
      541 cagaaagata atcatcagcg caagctgtgc cagataaaaa ataaaatatt ttaattcttt
      601 ttcgttcata ataatcagaa cgtttccaag taaatggatc agaaacataa aacctgtctg
      661 ccgtccataa attttacgca ttttttcctc tgacttcctg cctttaaaga cattaaagca
      721 ttggaatgta taaatggcaa aaaagataat caaaagatac ttagaaagct ctgtcaacag
      781 atgctccatt attctacccc tcgtttaaaa tgaccattcg tataagaatc cagcatgata
      841 tccggattcc aacgttcttt ttttataaat tcttgttcgt aataatcaag tattctcatc
      901 acctgttttt ttgattccgt cacaaactct agccgatatc ccttaaaatt catagacttt
      961 attttatttg catgttgaat caggcataac ggctgactgt tatagatggt attataacat
     1021 aattcacaat gcggcttaac catcatcttt tgtttcttcc gatcggtcaa aaaaacaata
     1081 gcgctatcct tcgtgcattg cccggtattc tttcgcaggc attgcgctga ttgcattacg
     1141 ggtaaatatc catatactac catctcacta tgactgtttt cacgatgaag caattctttt
     1201 tcattaagtt catatggcac tgtgaatgta cgataaccag ccttccaaaa cccctgcatc
     1261 gcataatcgg aaaatgtata aagaccggca tccaaaataa tccgatcctt agatattcct
     1321 agttcttcta acattccaat gccatcataa tcatttgcaa tataatttat attagataaa
     1381 tgtgaatatt tcgtgagaat tttcttaata tcggcagatg tctgttcttt aataacataa
     1441 ggaagacaaa gagcaacctt tttatccgta tttgacaaaa tatctaataa cttttctcca
     1501 ccaatcaaaa gatcgaaatc tacgtaaatt gcatcaacaa atgaacgctt gaggctatct
     1561 tccaattgtt ctatcgtgga cacttttaca gccatataag gtttcttatt ttccaaagaa
     1621 gaaaggtttt tatgatacac agtttcagca aaaacttcac gaggctttgc cagtaactct
     1681 tccatgagct cttgaactgc ctgtcttctt agcgtcttta gagattttgc gctataaaaa
     1741 acattatcgt ctaattcaat ctcaagatct gtaacttcaa acggagtcgt cccaaaagct
     1801 gccccttttt ttatcacttc ttctttagtt aatggtctag aagaggcagc caaaactgtt
     1861 tctccacata cacagacact tttatctcct gccgttaatg tcataatcgc aggttgatca
     1921 attcgaaatt ccatagaaat ccttaccgga attttttgtt ctacaaattc caaagatggt
     1981 tgttctttcg tcttcttttt atgcgaagga agtacaaatg taaccatctg agaatctacg
     2041 cagcctgtaa gatacccttt cgtaaaacca catcgattac cggcatttaa taacatttct
     2101 cggtcttttg gtgcaacttt aaaatctgat acctgctcta aagctatatc gagatattta
     2161 cgatacaggc taacaacctg gtatgcatat tctttttgtt tcattcgtcc ttcaatttta
     2221 aaagaatgcg ttcccgcttc taacatttgc ggcaatatat caatggttga caaatctttt
     2281 aatgacaata aatattctgc gtcatgcgaa accccatcca agttataaga aagtctgcat
     2341 ggctgagcac atcgtcctct attgccgctt ctgccaccaa tcaaagaact caacaagcat
     2401 tttccggaat aagaataaca aagtgctccg tgtgcaaaaa cttccaattc cgccttaacg
     2461 tttttatgaa tattggaaat ttcctgtaat gaaagttctc tagaaagaac tatgcgggat
     2521 gctccctgtt gttctagaaa cttagcacct ttagtcgatg tgatacacat ctgcgtacta
     2581 gcatgcaatt gcagatttgg aaatacattt ttcacaaaat caaatacacc ccagtcctga
     2641 actaacaaag catcaagacc attttttaca taaggatgta aatatgtata taattcatct
     2701 gctatttctc gattttttaa taaggtgttc accgtcagat agattttttt attatgtaaa
     2761 tgggcataat ccagcgcccg aagaagttcc tcttcattaa aatttttcgc ataagctctg
     2821 gcgccgaaac gctctccggc aagatatacg gcgtctgccc ccgcttcaaa cacagccagc
     2881 atcatctcat acgagccggc cggcgctaat aattctggca taagcaacct tcctttgaca
     2941 agtaaaaaag ctgaaaccat tgtataaggc cacagctctt tagattttat gatttagttt
     3001 cttctttttc ttctgttcca agcaaagcat cttcaagtgt tgtttcgagt tttgctttat
     3061 tcatcaacaa ttcacgattt ttactttcag aatcttttag tgcctctgac aaagtctctt
     3121 cattcatctt cgcagacaca agttcatgat tggcatcata aagctctcga tctttttcct
     3181 gaagttcttt ctccatgcga tctgcagttt ctttcgcctt aaaatagtca tccactatat
     3241 taatattcaa aagcacattc tttaagtctg ttgataaatg ctgatatccc tccaaagatt
     3301 taagttcatt catcttctgg ttaagatatg ctgcaacctt ttgtaaatat tcaggatttt
     3361 cataaccgct tagtgtatag attttgccac caatgattac ttccgcatca gattttgtag
     3421 ccatagatta cctctttttt tatttttcta tatttctatt tttattatat gtttttttct
     3481 tatatctcac aaccattaag ttggtaaatc gattccaaaa tgataatacg cttttggtgt
     3541 tgcaaccctt cctttaggag tacgattgat aaatccattc ataaccagat agggttcata
     3601 aacatcttct attgttccgg catcttctcc tagagaagcg gccagcgtat ccaatcctac
     3661 cggtccgccg gcaaaatgat gcatgatggt tgtgagaata tttcggtccg ttttatctag
     3721 tccttcttta tccactccca aaatatcaag tgcataattt gcaacttctt ttgtaatcac
     3781 tccatcatac tttacttgcg cgtaatcccg gactcttttc aaaagccgat tagccaatcg
     3841 cggcgtgcct ctagaacgac gtgccatttc ttctgccccg tcttgtgcaa tttctacttc
     3901 aagacgctgc gccgaattct taataatctg cgtaagttcg tccgttgtat aatactccat
     3961 gtgcatcaca acaccaaatc gatctcttaa tggtgcagaa agcaatccag ctcttgttgt
     4021 tgcacctaca agagtgaatc ttggaagttc tactctaatt gcccttgcac ttgcaccttc
     4081 tcctaccata atatcaatac aataatcttc catggctgga tataacagtt cttctacctg
     4141 cttattaagc ctgtgaattt catccacaaa gagaacatcg ccttcttcaa gtttgtttaa
     4201 aatagcagcc atctctcccg gttttgctat cgcaggaccg gatgttgttt taatattcac
     4261 tcccatttca ttagctataa tacaggcaag cgtagttttt ccaagaccgg gaggtccata
     4321 aaacagcaca tgatctaatg attcacctcg ttgctttgcc gcctgcatat atatcgacat
     4381 gttctctttg attttctttt gtccgatata atcatttaat tgctgcggac gcaatgagtt
     4441 ttcgaccctt tgttcttctt tatttaattg cgttgatata atacgcttct ccaatttata
     4501 actcctttaa tgcaagttta attatcattt ctatatcata accggaaata tcacccaatg
     4561 aattaatggc ttttaatgcc tgcgatttcg aaaaaccaag agattctagt gctgcaatag
     4621 cttgtgcttt ggcgctatta ttttcacttt gcgcggaatg tgcatttgat ttttcttcaa
     4681 aagcttcctc taaactgatt ttatctttca attccataat tgcacgctgc gccgactttg
     4741 tgccaacccc ttgtgctttt gatatcgtct tggcatcttc cgataaaata gcaaattgca
     4801 aatcatatgg cgtaagaatg gataatatgg ccagcgcagc tttaggacca atgccgttta
     4861 ccgatatcaa taatttaaac atcttaaaag attctttcga acaaaatcca tataatatta
     4921 gagcatcttc tctaacatac aagtaggtaa acaccttaac ttcatcacct acaaccccaa
     4981 gttcttcaat ctctcgctca gccaaaaata tctcatatcc gatattattg gtttcaatta
     5041 tgattcgatc agattctata tctgcaattg ttcctataaa ataagaatac atattttact
     5101 ctctttctaa gtgcgcactt gacgtttcca aaacaaatgt ccaacacgtt taatcatttc
     5161 atttccaaca atcccaatga taattccggt tactacgccc gcaatcatta aaaccgcaaa
     5221 ataatacata atattgtaat tttccacgac aaaagcagca acaatcaatt gtccaagatt
     5281 atgcacaata ccaccgattg cactaactgt aataacgtga aactgttttg tgtgtctaat
     5341 gaaaaccata atcgcaagcg acaatagtgc tcccgccatg gaatatagaa tactaaacag
     5401 attgccgaac aataaacctg caagaatcac tctaagcaca gaaacaataa gcgcttcctt
     5461 cggcccattc aaatataaaa ttaaaacaat cacaatattt gtgattccaa gttttactcc
     5521 cgggattgca atagcaaacg gaatcattgc ctcaacataa ctaaagacaa gtgccaaagc
     5581 caaaaaaacc ccaagaaatg caacattatg tttcatatga atcctttact ttgcgatagc
     5641 atcaactcca tcatctaagg acgcactatc atcatcacca ttttccaata tttcaactac
     5701 aactttatta ggtaaacaaa taatagattc attagcaaga tgaatcttac cttgttccac
     5761 acataattga tccggacaat cggcctcttc catagataca taaccatctt gaataattac
     5821 gacattcgta accgtatctt tagacgttac atatatggtc tcatcctgtt ctagtgaata
     5881 ttcaccatat atttctccat ctaccgaaat gcgaaccaaa ttaccgcttt ttgctcctat
     5941 cgtatgcatg ataacaaata tacaaactgc aaaagcaagt actagaccga ttaataacgc
     6001 atctcgtttt cgaaattttg gctgatagta ttcttccatc ctatatccgt tctcctatat
     6061 agtagaatcc tttacaacag acaagtttaa cggaaacaat ctgaccaatc agttctttat
     6121 tacccgcaaa atgaacaata ctattattcg acaatcttcc agaaaccaat tctttgtttt
     6181 gagaattaac agactcaact aatacatcca tcgttttgcc ttctaaagct ttcgcttttt
     6241 cacttgcaag ctgctgaact ctttttaaca atcgatcgaa tcgatttttg ataacctcag
     6301 gtgtgatttg atcgtctctt tttgctgccg gcgtaccgga acgttttgaa taaataaatg
     6361 taaacgcact atcatacttt acacgttcaa ccacatccat tgtctcaagg aaatcttctt
     6421 ctgtttcacc cggatacccc acaatgatat ctgtagtgat ggcaatatcc ggaaccgctt
     6481 ttcgaagttt ctccaccaat agaagataat cttcttttgt ataatgacga ttcatatctt
     6541 ctaacagttt cgtagagccc gattgaagtg gcagatgaaa atgatgacac acttttttag
     6601 aatgtttcat aaacataatc aattcatctg ataaatcttt tggatgcgac gtcataaatc
     6661 gtattctttc taacccttca atctgttcaa cctgctctag taattgcgca aaagtaatag
     6721 gatgctctaa gttcttgcca tatgaattta cattttgtcc aagaagcatg acttccacaa
     6781 cgccatccgc taccaactgt tttatttcat ttataatatc ttccggtttt ctgcttcgtt
     6841 ctcttcctcg tacatatggc acgatacaat aagagcagaa attattacat ccatacatga
     6901 tatttacgcc ggatttaaat ggatactttc gaacagccgg aaggttttct acaatctgat
     6961 ccgtaccatc ccagacttca accaccatct tttcttcttc aaaagatcgt acaatcagct
     7021 ctgcaatcat aaaaatatta tgtgtcccaa aaataatatc tacaaagcga tgtgcggatt
     7081 tgattttatc aacagccgac tgctcttgca tcatacagcc acataaagca atcttcatat
     7141 ccggattatg ctctttataa ctacttaaat atccaagatg tccataaatt ttgttgttcg
     7201 cattttctcg aactgtgcag gtattataaa taaccaggtc cgattcttct gaatctcccg
     7261 gcttataccc aatttgttca agaattccaa caattttctc agaatctctg gcattcatct
     7321 gacaaccaaa tgtatttaca aaataagtta atgctctacc tttttcctta gaaagaaaat
     7381 ctacgtattt tttagcctct tttataaaat aaaactgtct ttgcggttct gttgtaggaa
     7441 tatttattgt atctgtcatt tatctttcac catatcttaa tctttcaaaa aatcttctaa
     7501 caaaaagtct gtctgttcat tttttgcaaa caaagttcct gtatattcat tgtcaaacaa
     7561 atgatgcaaa caattcaaat cattactatt tgtaataatc atatctgctc cggatcttgt
     7621 tgctatcatt gcagcattca gtttcgtatg cataccaccg gttccaactc cgcttcctgt
     7681 cgaatccttt cccatctgca taacatcatc atttaattcc ggaacatatt ctatcaatct
     7741 ggcatattca ttttctcttg gatcgtctgt atacatcccg ttgatatcgg aaagcaaaac
     7801 caataaatct gcattcacaa gtgttgctac tagtgcagat aatgtatcat tgtcgccaaa
     7861 ttgcatttca tatgttgata ccgtgtcatt ttcatttaca atcggtatta cccccatcgc
     7921 aaataattct tcaaatgtat tatgtgcatt ttgtcgagaa ttaggtaaaa tcatcgtgtt
     7981 ttttgtcatc aacacctgtg caacggtctg gttatattca gcaaatactt tttgatatgt
     8041 catcataagt cttgcctgtc caaccgcggc gcatgcctgt ttttgagaat ttgaactcgg
     8101 tttattggtt aatccgattg cctgtcttcc aaccgcaatc gctccggagg aaacgaggca
     8161 tacgtcgatc ccgctatttc tcaaatcgca caattcacga acaagtttct caatcttggc
     8221 aaaatatata tttcctgttt cttcatgagt taatgaggaa gaaccgattt taacaactat
     8281 tctttttttc ttttcaatgc atggtctttt ttgcataaca ttcacctatc aaatattata
     8341 tttaaaatac ttcattataa tcccatctta agtaaaccat attttacctt atcacaaacc
     8401 cttataaatt gcatcatttt gttgcatttt ttatagcaaa atggtatttt tgtagaagta
     8461 attaagacaa accaacagaa agaaggatga tttggctcat gaacactaat tgccataacc
     8521 atcaaaagaa aattgcatta attaatgatt attcgggatt tggtcgctgt tctatcgcgg
     8581 ttgccttacc tattatttca atgttaaaag tacaatgctg cgccgttcct accgctattt
     8641 tatcaaatca taccggattt gatagttatt tctttgatga ttatacagac aacatggaag
     8701 cctatattca agaatgggat aaactaaatc ttacgttcaa tggcatatgc agtggttttt
     8761 taggctcaaa aaaacaaatt aaaattgtcg agaatttcat aaaaaaattc aagacagata
     8821 atactattgt attagtcgat cctgttatgg gtgactatgg caaaccttat gccacgtata
     8881 ccacagaaat gtgcagtgcc atgaaagaac ttgtgcatta tgcagatata ttaaccccca
     8941 acttaacaga agcctgcatc ttaaccgaca ccccatacaa agaacattgg aaacaaagtg
     9001 aactgaagac tatgactgaa aaactttttg atatgggacc tcaaaaaatc tgtattacag
     9061 gcattcctca aagaagtttt gttgcaaatt attgttactg gtcaaaaaaa gaacctcgta
     9121 ttattcgcac acacaaaatc ggggattcac gttccggaac cggagatgtc tttgcagcta
     9181 tccttgctgc tgacgctgta aatggcattg aatttattga ctcagtaaaa aaagcatctc
     9241 gttttattaa aaaatgtatc gaatgctcta ccaaattaaa tataccattg acagatggtg
     9301 tatgcttcga agaactacta tatactctaa agtaaaggaa ataacatgga agaaatctta
     9361 tataaagtac ataataattt atatgtaaat ctcacaaaca aatgtccttg cgcatgcaca
     9421 ttttgcttaa gacaaaatat ggatcggatt ggagaatcta attctttatg gcttgaccat
     9481 gagccatctt ttgaagaagt aaaagctgct tttgaacaat ttaatctatc agcctataat
     9541 gaggttgtat tttgtggttt cggcgaaccg acagaagctt tagatgtact tttacaaact
     9601 gcaaaatttg taaaaaacac ctataaaaaa aagattcgta tcaatacaaa tggcttaggg
     9661 aatcttgtaa acaacaaaga tatcacacct cttttcaaag atttaattga tactgtttca
     9721 atcagtctaa acacctcgaa cgctgatgat tatcacaaac tggttcaaag taaatttggg
     9781 gactgttctt ttaacgaaat gctaaaattc gcagaatcct gcacaaatta tgtgccaaac
     9841 gtaatactta caactgttga aacaactata tcaaaggatg atgaagctgc ctgtcaaaag
     9901 atatgcgaca aaatcggtgc aacttatcga attcgtcctt gggaagatta aaaaaaacag
     9961 ctgctcacaa tgagcggctg tttttttaca tcttgtctaa ttaataaatg atttttttag
    10021 gacacttctt tgcacaaaga ccacaacctt tacatagctc ctgatcaata tatgcaatat
    10081 tatccacaac atgaactgca tcaaagtgac aggatttttc gcataattta catccgatac
    10141 atccaacctc acaagactgc ataacatctt ttcctttgtc tttggaacta cagtgcaccc
    10201 tgtattttgc cttataagga acaagttcaa ttaaattctg tgggcaggct gttatacatt
    10261 tcttacaagc cttacactct tctttatcta caactgcaac tccattaacg atatgaatcg
    10321 catcgaaagg acacgcatcc acacattctc catatcccag gcagccataa tcacattttt
    10381 taggaccgcc acccggaaca aatttcatca tatcacagct ctcaacaccg taatagttat
    10441 aatttatttt tgctttatcg caatcaccgg cacatttaac aaaagcgacc attttatcac
    10501 cggcctgtgc ttcgactccc ataatttcgc caatcttggc agctacagga tctcctccaa
    10561 ccggacaagc tgaaatctct gcttctcctt ttgcaattgc tgcagcaaga ccggaacatc
    10621 cagcaaatcc acaaccacca cagttgttac ccggaagaac atcaagtact gcttcttcct
    10681 tcggatcaac ttcaacctta aacttttcac tggaaaatcc caggaaaaat ccaatgacaa
    10741 cacctactac ggcaacaatg atagcggcaa taataacagc agtaatactc atattcaagc
    10801 cctcctaaac tacgcctgac catccaaaga atgcaattgc cattagtcct gaagtaatca
    10861 gaacaattgc ggatcctttg aacggagtag gaacatcatt gtattcaatt ttttcacgga
    10921 taccggcaag aatgacaatt gcaatcataa agccgatagc tgtcgcaaaa ccacttatta
    10981 cactcacacc aattccataa tccttttgaa cattcgtaag tgcaatacca agtactgcgc
    11041 agttcgtagt aatcaaaggc aggaatactc caagtgaatt ataaagtggc ggcatctgtt
    11101 ttcttaagaa catttctaca aactgcacaa gtgcagcaat taccaaaata aaaacaatag
    11161 tccttaaata aaccagatca aatgtttgta aaataaattt atcgatgaca ctggttacca
    11221 gtgaagcgat tgtaataacg aagataacgg ctcctcccat accactggct gtttctattt
    11281 ttttcgaaac accaataaac ggacaaaggc caaggaactg gctaagtaca acgttattaa
    11341 caatagccgc actgatggct aataaaatta cgtctttcat ctgtactaac cctcctactt
    11401 atcaacatcg tcggctgttt tagtcgactg cttatctgtg ttatctgctt tctcttctac
    11461 cttagtttct accgcttctt tttcagaaac agcatttacc tgaggcattt tttcttttgc
    11521 ttcgagtttt tttgcttctg cttctttttg cttttctgca gtaattctct cagcctcacc
    11581 atttccttca attgaaccgg catttgatgg aagtggtttt cccttacgag ctgcaacaac
    11641 tttaacctga ttcataattg cgaccaggaa tcctaatacc aagaatgccc ctggcgccaa
    11701 tacaaaaatt gtaatcggtg taaatcctgc tttaccggtt gcttcatccg caagtggaag
    11761 aatctgtgct ccaaaaagct gtccggcacc taaaatctca cgcacgattc cgatacaggt
    11821 taagccaaat gtaaaaccga ttcccatacc aattccgtca aaaattgaaa taattgggcc
    11881 attctttgat gcaaatgatt ctgctctacc aagaataata cagtttacaa caataagcgg
    11941 aatataaatt ccaagtgaag aataaagtga aggtacaaat ccttgcaata aaaattgaac
    12001 tacggttacc aatgtagcaa caactacaat atatgccggt acacgaacac gattcggaat
    12061 aatattacga agcaatgaaa taatcaagtt cgaaaatacc aaaacaaccg ttgtcgataa
    12121 tcccattcca agtccattaa tagcggaagt tgttaccgcc aaagtcggac acataccaag
    12181 catcaatacg aaggtagggt tttctgtcaa aagaccattc tttaatcgtt ccacatactt
    12241 attcatttgc actacctcct tgtgttaatt cagtattaaa atatgcaaga cctgcatcta
    12301 ctgcataagt aactgctttc gatgtaatcg ttgcaccgga gatagcatta atttcatcgt
    12361 ccgaagttga gcctgtcttt gttacttcaa agtattcgac ctgcttattt tcgaactgcg
    12421 aataaaacgc ttcttctttt gctttcatac caagaccggc tgtttcgcta atatcggtaa
    12481 tcgaatatcc attcaaggtt ccatcattag taacacccat ggataatgta atatctccac
    12541 catatccggc atgagatgtt accgtgatca catagccaat cgtattgcca tcagcatcca
    12601 aagctgttgc aagtccttcg atttcatcat ccggaaaatc ggaagctatt acctttgttg
    12661 ctgcggtcgt atcaaagtct tcctcttctt caaaagactc agcatcagca aataccgctt
    12721 tatacgcttc ttgctggata ttataatttg cctgtgctat aggctctaat gtaatttcgt
    12781 ggacgaaacc taagagcaaa ccagcacaaa gcgtaataat cgttaagatc atagcgtctt
    12841 ttactactgc cttattcatt agctttcgcc tcctttttct ttttttcttt tattacacca
    12901 aatgcatttg gaattgttac tctctcaatc aaaggtacaa gcatattcgc aaaaatgata
    12961 gaatatgata caccttctgc agatgctcca aacaaacgga aaataccggt cagacatccc
    13021 agacagatac caaatacaat cttacctctt ggtgtaatcg gtgatgttac ataatcggtt
    13081 gccataaaga atgcacctaa aataatacca cctgagcaaa gctcttctac aatataattt
    13141 ccgtctaaac cgtgtccgct aaacaggatg ataaatacaa caaatgtaat taaataagtt
    13201 cccgggatac gaagatcaat cacacccata gcaagtaaga aaatcgcacc aataagcaaa
    13261 cacaatattg aagtttcacc aattgtaccg gcatgtgttc ctaaaaacaa gctcattgtg
    13321 tcgtaagaac caccgtcttt aataatcgcc agtggagttg ctccggatac tccatcataa
    13381 gtaaagcttg tcatacttcc cgtaaaggaa ataagaagga aacaacgagc tccaagtgcc
    13441 ggattcataa agttttgtcc caaaccacca aagagcattt ttactacaac aatagcaaac
    13501 acaccaccaa taaccgcctg atatacaggt aaggttgacg gaaggtttaa tgcaagcaat
    13561 aaaccggtta ccactgcact taaatcactg attgtacttt ttttatgaac aatcttttca
    13621 aatatccact ctgaaagaac gcaagctata attgttgcga caatcaaaag tagtgcccta
    13681 gctccaaaat ttacaatacc aaaaatcgtt gccggaagaa gtgaaatgat cacatacagc
    13741 atgattcgat tggtagaaac tttagctcgg acatgcggtg aagatgatac attaaacaaa
    13801 tcactcacgc taatccacct ctttctatcc aattatttct ttctcttgtt agcaattact
    13861 gtttttttca tggatttaat tgactgtgcg agactacgtc ttgccggaca tatataacta
    13921 cagcttccgc attctataca ctctaatcca ttccagtgtt caaacatatc ttcaacatga
    13981 ttttcggcaa aatcagcaag ccttgaagga acgagctgtt ccggacagac ttctacgcat
    14041 cttgcgcagt ttatacatgc cgtcgtttca tattctgcca cttcatcttt tgtaaagcaa
    14101 agcagtgccg atgttgtttt tgtagtcgga atatccaaac taaataatga aaatcccatc
    14161 attggtccac cagaaatgat tttttcaggt gttgatttga agccacctgc ggcttccacc
    14221 aattctctat aatttgtacc aatacagata ttgtaattag ccggattgac aacagcatta
    14281 cccgtaattg ttacaatacg atgcatcaaa ggacgaccaa gttttacagc acgataaata
    14341 gatacaattg tatctacatt gtccacaata catcctgcat cagccggaag cattttcgaa
    14401 ttaattgctc taccagttgt tgcataaata agttgacgtt caccaccttg tggatacttt
    14461 gtcataagag gcatcacaga caatcttggt tcatctttta caagttcttg caatttggca
    14521 atacaatccg gcttattatc ttctacaccg aaaattcctt tcgcattgtc aaataatcga
    14581 agaataattt tcataccttc tatcaatttt tctggttctt ctagcattct tctgtaatca
    14641 gatgtcaaat atggttcgca ttctgcgcaa ttcgcaatca catattcaat cttatttggc
    14701 tcctttggag acaatttaac atgtgttggg aatcctgcgc ctcccatacc tacaactcca
    14761 gcttctttga tcttcccaat aatgtcttct ttgcttaaag aatcaaggtc atgtacttcc
    14821 tcaaattcta cagcattaaa ctgaccatca ttttcaatga taatagaatt aaccatatct
    14881 ccaacaacta cccgacgcgg ctcaattgct tttactttac cggatactga tgcataaatt
    14941 ggagcagata caaatccgct tgcttcggca atcttttgtc ctgccaaaac ttcgtcacca
    15001 actgcaacaa tcggagttgc cggtgcgcca atatgctgag ataatggata taccatatca
    15061 ccagtgggca aataatcagt tatcggctga tccttagata actctttgcc atcataagga
    15121 tgagttccgc ctttaaatgt acctaagccc ataagttttc cccgctttct taattatttt
    15181 ttgcaatcaa ttaaaattat atcacattgt tttatcctat tgtatactaa ttttgaaaac
    15241 tttttaacaa tctttttagt ttcttttcat caaatttcat aatataatat gtattatcaa
    15301 gattaatttt agttcggagt gacaaactat gaagattttt cagtcaaaaa aggaaattcc
    15361 acacaaaatt gacttttttt caaaacattt ttttaacaat cctttgttct acgacattga
    15421 aacaaccgga ttttcaagag actttcatat gatatacatg attggaatcg ggaaactcgt
    15481 taatgaaact attgtttcta cacattttct tgccgaaacc aaagaagatg aagtatccat
    15541 tatcaaatct ttttttgatg ctttgtcaga ttctgatttg ctgatttctt ataacggcaa
    15601 acgttttgat ttaccattta ttattgcacg cgcacaaaaa cacagccttt ctctcccact
    15661 aatattcccg gaagaattgg acatctatct agaagccaaa ccactctttc gccttttacc
    15721 gacacctgac caaaaattaa aaacaatgga acattatctg catatcacca gaaatgacaa
    15781 gatgaccggc ggcgaattga tcacggtttt tcaatcttat ttgaacacgc atgatgcaga
    15841 aagtgaaacg ctattgctta agcataatac cgaagatatc ctaaatctac ccgaacttat
    15901 gcaacttcta tccatcaaag aaatattatc ctttgagcat ctttcaaatt tcaattattc
    15961 tatcgaagaa tttaccggag caaatggcaa tccctgcaaa gaattagcct taagttataa
    16021 ccactcctgt accataacga attcttttat tttttattgt gatcaattct ttatcagaat
    16081 tgatccgtca aagatacgga ttcaaattcc aatcaaaacc ggaaatatgc tttattttta
    16141 tgataattat aaagactatt attatcttcc cgaagaagac cgcgctattc acaaatccgt
    16201 agcatcgttt ctacctaaag aacttaggca aaaagcaaag gcttctaact gctaccaaaa
    16261 atacgaagga gattttttgc ctaatccaaa caacatattt tccccttcat ttaaacaatc
    16321 ttacaaaagc aaggattctt ttcttgcgct tgatcaatcc aaggattatc tcttgtctca
    16381 tataaaaaaa tacttgcaaa cacttctcac gctataaaaa aaagaaccga atcaaatcgg
    16441 ttctttttaa tctcataatt acaattttct aaagaagaag gattgctctc gagaataatt
    16501 aagctcttta tagttgataa tctgttccgt actaccaata aacaaaacac caccctgtac
    16561 cagagcttta ttatatttct tgtagatttc ctcttttgcc tcatcggtaa agtaaatcaa
    16621 aacatttcga caaacaatta aatgctgacc tgacatatat ggatctttca gcaaattatg
    16681 ttctttaaaa gtaacacgtt ttttgatttc ttctgaaatc tggtacgaat taccaatttt
    16741 ggtaaaatac ttttctttaa gatcctttgg aacgccagca atactctttt cgttatatag
    16801 gcccaccttg gcagttgcaa ttacttgctt atcaatatcc gttgctgtaa tacgaatatt
    16861 atttagtggc aaatgtctcg acaaagccat aaccaaagaa taaggctcat ctcccgttga
    16921 acacgcagca ctccatactt taagattctt tccaaatctt tgaatcaaat ccggaataat
    16981 ctcttcatcc aaaagcttcc actgctcagg atttctgtaa aattcagaaa cattaatagt
    17041 taggaaattg acaaattctt caaacttagc cttgtctttt ttgattaccc caacatactc
    17101 atcatattcc ttgattccat tctttgcaat caacgtatct atacgacgct tcatctgttt
    17161 ttccttatag gaactcagat cgatttttgt catcatataa atatcttttt taaatttttc
    17221 gtaatcgttt gccaattaaa gcactccctt cacatggaaa attactcttc ttccgatgcc
    17281 tcttctacag atgcttgttc ttcttccgct ttttcttcct gaggaattaa agctttcatg
    17341 ctcagagaaa tcttatgatc agcttcatta aaatcaacaa tcttagcttc aatttcttga
    17401 ccattcttca atacatcaga aggcttttcg atatgctcat gtgcaatctg agatacatga
    17461 agcaatgcat ctacacccgg tgtcaattca acaaatgcgc caaaatcagt catgcgagca
    17521 acttttccgg ttaccacatt tccaaccgcg aacttttcac ttgcatcatt ccaaggattt
    17581 tcatccggga acttcatact aagagcaatc ttggtatctt tgatatcttt gatatatacg
    17641 cgaacttcgt cgccattatt aaagagtttt ttaggattat caactctccc ccaagacatc
    17701 tcagaaatat gtaaaagacc atcagctccg ccaaggtcaa caaatgctcc aaaatctgtc
    17761 acattcttaa tagtaccctg aatcacatcg cctacttgaa tcttctctaa taattctttt
    17821 tgaagttccg ctctcttagc gataatcaac tgttttctat ctccaataat tctacgacgt
    17881 cttggattaa attcagtaat tacaaattca atttcctgac cttcatattt agaaaggtct
    17941 ttctcatatg tattagatac aaggcttgca ggaataaata cccttgcgcc ttcaacatct
    18001 acactaagtc caccgctctt cacttcatca acaacggctg taagcacttc ctgattgtta
    18061 aatgcttcct ccagtcgctg attacctttt tcagcaagaa ctcttctgta agataaaaga
    18121 atctgtcctt ctccatcatt tacttttaca accttaacgg tcatattatc gccttccgaa
    18181 acaacagtgg taaggtcaag attcgagtca tttgtatatt catttctcgg aataattccg
    18241 tctgatttag cgccaacgtt caaaacgatt tcatctggtc ttacttcaag aacaacgcct
    18301 tcgactacct ccccatttct tattgttttg tcataatctt caagcatttc gtcaaaattt
    18361 cctgtttctg acattagttt gaacctcctc aataattttt tttggggtgg aagccccagc
    18421 agtaataccc acgcttttaa tgcctttgaa tatagatccg tctaaatcag ttgatgtctg
    18481 aaccaagtag gtacatggac atcccactct tgaaatctca aataattttt gagtattaga
    18541 actgttttta cttccaatca ccagcattgc gtctacgtct ttagacaatt gtatcgcctc
    18601 tgattggcgt acttcagtgg cattacaaat tgtatctaaa acatttatat cataaccttt
    18661 tttatttata atttcaacta aattcttaaa tttattatgg ttaaacgtgg tttgcgcgac
    18721 aagtactgtt gacctatctt tttctatgcc taatttctca aattcagaag ctgtctgaaa
    18781 agtctgtgaa ttatccggcg aacaccatcc caaaattcct tgtacttccg ggtgattctt
    18841 atcaccggca attaatatat aacaaccttt tctttcatat tccgcaacta aatcatgaat
    18901 tttgcgcaca aaaggacagg tcatatcaca atactcaata ccgcgataat ttaataactc
    18961 ataaatctct ttgcccactc catgtgatcg aatcacaaca attccatctt gaatttcaag
    19021 aagttcttct ttcgaatgaa gaaccgtaac tccgcgactt tcaaaatgct gaattacaga
    19081 ttcattatga ataatcggac cgtaagtata tatcttttga tccgtcttgg tctcaaccaa
    19141 tttttctaac gaatctactg ctctttttac tccgaagcaa aaacctgcac tcttagcaac
    19201 aataacttcc atttcttacc tttcttcata tagatttatg attgtttcac aaacctgttc
    19261 aattgtcaaa tttgaagaat caaccaaaac tgcgtcttgt gcctgcttca atggagcaat
    19321 agttcgattc atatcttgat agtctctttg ttcaatatct ttttcaattt ctgtaatatc
    19381 gcattcaaca cctttttcta caagttcatc aaatcttctt tttgctctcg tttgcaccga
    19441 tgctgtcaaa taaatcttta gttcagcgtc cggtaataca catgtaccaa tatctctccc
    19501 atccattatt acattctgct tttgagcgag ctctttttgt gcatccagca gcattgcgcg
    19561 tacttttgga taagaacttg tttttgaagc catattcccc acttcttctt tacggataaa
    19621 tccatttaca ttttcgccat ttaacagcac ctgttgttct ccattcacat attgaataga
    19681 aacactaatt tgatcacaag cctgattcac cgcttcttca tccgatacat ctatgttatt
    19741 tcttagcata tacaaaccga tagcgcgata cattgcgcct gtatccacat aaatcaatcc
    19801 aagattcttt gccacttttt tggctatcgt actttttcct gcaccggcag gtccatctac
    19861 tgcaatattt tttcccatat caacattctt cctttcattc gtctattaca ttcttatcta
    19921 gaacactttg cgttgcaaga tatccggttg accatgcaat ctgaagatta taacctcctg
    19981 tcaacgcatc aagatcaagc atttctccgc acaaataaag attctttacg agttttgatt
    20041 ccatagtgga tggatcaacc tctcgaaccg atacgccacc ttttgtaatg atagcttcgg
    20101 aaaatccacc caattcctta cttgtaaggc gtagtccttt caataattca actagttttt
    20161 ctcgttcttt ctttgtcact tcatttactt ttttctttgg atcaattcca cttaacctaa
    20221 caatcaccgg aatcaactta gaaggcaata atttattcag actgttgcca aattgacgat
    20281 taatatttgt ttgaaaatcc cgcaaaattc gtttatccat ctgttcctta tcaagagctg
    20341 gttttaaatc aatccaaata tcaacagttc ctgtttttag ctcatcattt aatacagagc
    20401 tggctgtcaa aacaacggga ccggaaattc ctttatgcgt aaaaagcatc tcgccttgtt
    20461 cttcatagag acacttctta cccctttcaa aagaaacttt tacatttttt aatgaaagcc
    20521 ccattaattc agttacccac tcttcttttg tcaaaatacc gacaagcgat ggtgcacatt
    20581 cttttattgt atgccctaat ttgttaacaa gttcatatcc gctaccatca ctcccacaag
    20641 acggatagga tattcctccg gttgaaatga ttacagcatc tgcttcataa cacgattttg
    20701 aagtaacgac tgcacatacc cgctcgtttt ttactttgat ttgagtaact ttttcattta
    20761 gcttaatttt aacttgtccc tctttcatag cgcgttctaa tgtctttatt acatcagagg
    20821 catgatccga caccggaaac accctatcac catgttctgt ttttaatttc aaaccatgtt
    20881 cttcaaaaaa acgcatcacc gaagaactat caaatgaata aaaggcacta tataaaaatt
    20941 taggattacg ttttaccatg gataaatgtt tttcgacatc cgaattattt gtgatattac
    21001 atctaccttt tcctgtaata tatagtttct ttcctagctt ttcattttgt tcaatcaacg
    21061 tcacatcaca attttgcgca caagttgccg cagccatcat tccaccggca cctccgccga
    21121 ttatcactac ttttttcact tcagctcacc tatatgctta tatttatttt taaacgcatc
    21181 atcaatatga tcaatttcat cattttcata aatctgatac tgttcccaaa tatcttcaag
    21241 aaattcaacg ttttttacta cttcatcttt gcgaaacata gttaacgcca caataagagc
    21301 attaatcacg ctcataggtg ccgtcatgga atccacaata gatgccattt cacttttcgc
    21361 aatcagatta caggaggaat aaagattcat aggcgaatga acggaatctg taagcgttat
    21421 aaccccagca cttttattgt tggcaaactc catagctttt agtgttcgca tcgaatatct
    21481 cggaaaactt atcccgatca caacgtcttt atttgtcaaa tgaaccatct gttcaaacat
    21541 ctcggtcaca ttactcgaag ttacaagatg gacattctta aaaatcatct gcagataaaa
    21601 atataaaaac tgtgcaagcg gcgcacacgc cctgactcca acaacataaa tatgttcagc
    21661 gtttaatata gaagacacag cctgatcaaa tgtactttga tttaaccctt ccaacgtccg
    21721 ctttatgtta tcgcaatcgg acgcgagaac tttttgcaac acatcttttt tggacgttcg
    21781 tgttgttgta atattcattt tctgtgtttt ttctaattta agacgaacca tttcttctaa
    21841 tgatttttga aactgcggat accctttata tcccaggctc atggcaaatc gtaccacagt
    21901 tgattcgctc actcccacaa cttctcccat tttcgcagcc gtaaaaaaca ctgcctgttc
    21961 ataattatcc gttatatatg cagcaagttt tttttgattt ttactcattg aagcatattg
    22021 ttcattcatt ctggtaagca aattattcgc attcactttt cgctcctcca ctcgtataca
    22081 ttgttcgata tattataaca aagccctatt tccttagcaa gaaaatgcaa atataaattt
    22141 attattaaat actgtaagat ttcttagatt atgttgcacc attttcactt ttcaattatc
    22201 attggaatat gaataatttt acaaaggatc gtgactaaag aattatgaat ttatcatctt
    22261 caaatattat taaactctta gagaaacatg cacaggaaga tccggatctt gttatttatc
    22321 gtttcgttga ttatcgagac gatgaatttc attttcaaga ctgtaccaat cgattgattt
    22381 ttcgtaaatc tttggaaatg gcatacgaat taaagcgaaa aggtctaaaa aagggggatc
    22441 gggccgttat tttttctatg caggattttg gtactgttta tgcgatactt ggatgtatga
    22501 tggccggagt ggtatttacc attattccac caccgctcga tgaaaataaa gttgcgagat
    22561 ttatatcggt attaaaatca tgtcgtccta aggcgttaat ttcaaactac gcgcttgaac
    22621 aagaaagcga aacaaaatta acggctcgtt tgttaaagga cgcttttttt aatgtcatca
    22681 ccttaaagcg aatttatacc gataaattaa ctccatataa aaatacggat gttatcgttt
    22741 cgcaaaatcc gaacgattta gtatatctcc aatatacttc cggctcaacc agcgcaccaa
    22801 aaggcgttat gattcgtcgt catcaattaa tgagtcaaat gcagcaatgc gataatgtat
    22861 atgatttttc caccagcaga atggcaacct gggttccttt tttccataat ttaggacttg
    22921 taatcacagt attaatgcca ctttgcgtta atggtgctgt tatttatcat attaatacca
    22981 tgcaattttt atccaatcct aagatttgga ttaaacttat gaataaatat cgctgcaacc
    23041 tgacggttgg tcccggctct gcatttgaag catgcacgaa aatcttctca ccacaagaag
    23101 cttcaaagat tgatttgtca tgtgctacgc actttatgaa cggttccgaa ttcgtttctc
    23161 cgcagaccat cgctaaattc agcgaaatgt ttaacgtgcc ttatcatgcg gccgctcccg
    23221 gctatggcct cggcgaatgc tgttgtcttg caagtgttgc aggtcttgat tataaggtct
    23281 tacgcgtaga ttatgaatct taccaaaaaa acaaaattgt attatcagat gctccggatg
    23341 caaaggaaat tgtcagcctt ggcaaaccag ttaccggtct taaaatcatt gctgtcaatc
    23401 ctaaaacgcg aaaaacctat gacgaattac atattggcga aatctgtctg caaggtccta
    23461 atgtagcatc cggatattgg ggcaaaattc cggaaaataa aaatttccat tttcgtctaa
    23521 ccgatcaaga aggcgatttt tatcgaaccg gagaccttgg ttttatgtat gaaggcaatc
    23581 tttatattac cggacgccta aaagaaatgt tcattattaa cggacacaat gtctatcccg
    23641 gtgatttgct cggatatctt caaagacaca gtccgtctat taccgcaaat gcctgcggtt
    23701 tcttttcgat ttctgacggt aagaaagaac atatttatgc cgtaatggaa ttcgaggata
    23761 ccgacaatta tattaattat gcttctcgaa tcaattcttt gattgcaaag caatttgagt
    23821 tttcttttta tgatatttta tttgtaccaa agaactctct tcctcgaaca gacaataaca
    23881 agttgcaaat gttaaaaacc cgtgcgttat atgagaagaa agaacttccg atcctattta
    23941 gctatcgcac aagtaatcac tctaattata cagtttcttc aaaagaatct gacggcgcac
    24001 atgctaatga agacaaaaat gatgcgatct ttacaaaagt taaagaaatg tttgaccgtg
    24061 ttcttaaact agactcctat aatgtacatg atagtttttt agaacttggc ggtgactccc
    24121 ttatgggatt tgaattatta aataaaatcg aagaagattt tggcatcaaa atggactttc
    24181 gtgaattgct tgcagatgct tctgtttacg gagttaccaa tcatatcaag cgcgttcttt
    24241 ccggcaaaca accaagtggt aagccaattg atttaaagat ggaatgccgc cttgataaaa
    24301 gcattgtacc gcaaggaagc tatgagaagt caccacaaga atgcagcaag atatttttaa
    24361 ccggttcatc cggattttta ggttctaacc ttataaaatc ctttatccaa cagtatcctc
    24421 acgacgacct tgaaatctat tgccatgttc gtgcagaaag cactgaaaaa ggatacaaca
    24481 aaatcaaaaa tcgaatgatt cattttggct gttggaatga agaatatagt aagttcattc
    24541 gtcctgtact cggtgattta acaaaaccga atatgggcat ggatcaggag atttataatg
    24601 aattaagcaa taaaatcgat gttgtgtatc ataatggagc tttattaaat tttgtttatc
    24661 catattctta tttgaaaaat acaaatgttt atggcactat agaagcattg cgatttgctt
    24721 gtgccaaaaa accaaaatat ttccatttta tttcttcata cagcgttttt gacacgccgg
    24781 ataatcttgg aaaatttgta acagaatcac agccgcttaa tacttccagc ggattttcat
    24841 tggcttattc tgagacaaaa tgggttgcgg aaaaactggt tggtatcgct aataaacgag
    24901 gattaaaaac tgtcatttac agaccgggcg atatcaccgg cggcaaaaat ggaatttgga
    24961 atctcgagga tatggtaagc cgcattattg ttggttgtat ccagcttggc tgcattcctt
    25021 ttgcgattta cgaactccac atgacaccgg ttgactatat cgcagatgca attgctcata
    25081 tatcacaaaa agaagaagca atttccaaaa acttccattt aatcaacccg gtaccactac
    25141 ctcttggaaa gc
//
