LOCUS       c00025_NZ_BJNT..       14006 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BJNT01000026.1 Corynebacterium variabile strain NBRC 15286
            sequence26, whole genome shotgun sequence.
ACCESSION   NZ_BJNT01000026
VERSION     NZ_BJNT01000026
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:57:26
            Original ID  :: NZ_BJNT01000026.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14006
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14006
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[547:4006]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      548..4006
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14006
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14006
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(81..425)
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MSANTALETRTPTNELAYLDGFVPSTFDAPHSSLHRSATWIGMGL
                     ILVSLAGFGTFVYGFGVNSDTTSPMADDGSMIGIIGLIAGLGLLFAGFFLVHAGRKNYR
                     AYKKASGRVQ"
     CDS             complement(548..1297)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-12, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.2e-09, bitscore: 29.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.8e-25, bitscore: 80.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-07, bitscore: 22.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLHLEIWRQADRNAQGHFESVDVPDAVESMSILELLDHVNSSYV
                     EAGKEPFAFASDCREGICGTCGLLVNGRPHGPDQNKPACQQRLFSYSDGDALKIEPMRS
                     AAYPVIKDMVVDRSALDRVMEKGGFVSIVAGTAPDADHLLVNHHDAELALDHAACIGCG
                     ACVAACPNGAAHLFTGAKLVHLTLSPLGRMERGRRAKAMVDEVEGTFGPCSLYGECADV
                     CPAGIPLTAVAAITKERARAAFKGKDD"
     CDS             complement(1297..3330)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 209.3; E-value:
                     3.5e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-64, bitscore:
                     209.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.1e-35,
                     bitscore: 111.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGMSKPHPHNQTADFNYDEALAAFQAPESQVDGVTVGKVIGDNAP
                     HEVSQQQQWQFDKEHFKLVSPLNRAKFKVLIVGTGLAGGAAAAALGELGYNVKVFTYHD
                     SPRRAHSIAAQGGVNSSRAKRLDNDSTYNHTKDTVKGGDYRCRENDCWRLAMESGRVID
                     HMNAIGAPFSREYGGTLANRSFGGVQVSRTFYTRGQTGQQLQLATTSALYRQIGAGNVE
                     IFTHSDVQDVIVEDGVCKGIVTRNIITGELSIHTGHVTVFATGGYGNVYHMSTLAKNSN
                     ASAIMRAYEQGAYMASPSFVQFHPTGLPVNSDWQSKTILMSESLRNDGRIWTPKKKDDQ
                     RDPMTIPEDERDYFLERRYPAFGNLVPRDIASRANAQQINAGYGVGPKKNSVYLDLTHA
                     IKNLGEDVIRERYSNLIQMYEEAIGDDAYKTPMRIAPTCHYTMGGLWTDFHEMTSIPGL
                     FCSGESSWMYHGANRLGANSLLSSSVEGWFTLPFTIPNYLAPLLGTDIPDEDSAAAKAA
                     LKRTEDRLNNILNIRGPNPHGAEYYHRQLGEILYRCCGVARNVKDMQEGIDEIRAVRKD
                     FWENVFVPGGTAEMNQQLEYAIRVADYLDLGELMCVDALDRDESCGAHYREDHLDEEGE
                     AKRDDDNWCFVSAWEPAGDEKFIRHSEPLYFDRIPLMTRNYK"
     CDS             complement(3359..4006)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="SucD_FumR (E-value: 4.1e-08, bitscore:
                     24.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLTMAVTGIIFVLFVLFHMVGNLKVYTGEGHFNDYADFLRRMGE
                     PVFPHETVLWILRVVLIICLVLHVYCAFALEARSKQSRGSEKRFGKVKNFNTFTASSML
                     GTGAVLLLFIIFHILDLTIGKGVATDAFEHGEAYGNLVESFNRPWVAIIYILCMVVLFL
                     HASHGIWLASSDLGITGHRTRQVILWIAYLLPAIVMIGNISIPVAVLCGFGS"
     CDS             complement(4328..7042)
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="VTDSNDRTDHLEEFLAQRRRVASVVNRPVGDGGGPADPTDYFPPG
                     YRTDVHLDDVDPLELVDRTNHPVDEWGWHERRPVRSDAELGLSETVFALSNGYMGLRGN
                     PPEGRDSHEHGTFINGVHETWNIEHAEDAYGFAREGQTIVQVPDAKPIRLYIDDEPLRL
                     GVAEVEDYGRTLDFREGVERRSFIWRTQSGKRVRVVTDRMVSFQERHLALMSLEVELLD
                     SDAAVVISSQILNRQDGEDEFSSILDTYAASSGAADRAYAHAADVNGGGDPRKAEKIAG
                     RVFQPTYRASSEDQRVTLGYRVTNSGMTVAVSMDHVLDVTQAQGTGGSGAPASSDAVGG
                     VEMHTEMRDDVARVVYHVDGTRGLRLRLEKFVSYHSSRHVSAEELAFRCARTINRARQV
                     GYRTLQANQAEWLGKFWRRSDVRIPGHPELQQAVRWNLFQLIQASARAETQGVPAKGLT
                     GSGYGGHYFWDTEVYALPFLTYTNPQFSRNALRFRYLMLPQAKERARELSHDGVLFPWR
                     TINGHESSAYYAAGTAQYHIDADITYALMKYVYATGDAEFLLDEGIDILVGTARFFMSL
                     GFFETTGEKFQIHSVTGPDEYTTVVNNNLYTNVMAQYNLRVAADVARQMRSERPEAFQN
                     LADRTGLSEDELDLWDRAAEAMYIPFDERMQIHPQDDQFLNRQLWNLDDPAVGAKRPLL
                     LHYHPLTIYRYQVLKQADVVLALFLQGRDMPTEVKKRDYAYYDRLTTGDSSLSAVVQSI
                     MAAELGFRDTAMRFFLRGLFLDLENLHGNSADGAHIASCGGVWSALVFGFGGFRDDYGR
                     FSIDPRLPEGWDELEYNVTLQGYQIRVSVEKDAVELQIVDGGEGLVGPVTVLGQDVVIG
                     SAPVRVEGTTTLVSEEDGLSESVPSADVVFVEK"
     CDS             complement(7094..7948)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_6"
                     /sec_met_domain="HAD_2 (E-value: 3.4e-09, bitscore: 28.7,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMLLHRARRPRATYDGGMTADLPDALPDLAAFDAVLFDLDGVITP
                     TADLHRQAWSVVFTRYFVERGVAPYTEQDYFDHIDGRPRSEGVAAVLASRGITLPADRS
                     DPAWEGEKGEDAPTDETVLGLGLLKNSDFLALLDRGITAYPGSVALLDALTAPGTTTRV
                     AVVSSSKNARPVLTAAGLIDRFEVIIDGNVAAAEGLPGKPAPDTYSYGAELLGVPSTGA
                     VVVEDATSGVAAGAAGDFGLVLGVDRGAGAQALKDAGADVVVADLADLVDRLGTSDGSS
                     AVR"
     CDS             complement(8136..10340)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Malate_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_7"
                     /sec_met_domain="Malate_synthase (E-value: 6.3e-171,
                     bitscore: 560.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQTQRITAGGLEVAKTLYDFVNGEVLPGTGVDQEKFWEGFGAI
                     VAKHTPRNRELLAKRDDLQAKLDEWYTQNPGTQDAEKYTAFLKEIGYLVDQPEDFEIRT
                     ENVDAEFATTAGPQLVVPILNARFAINAANARWGSLYDALYGTDVISEENGAEKGKGYN
                     KVRGDKVIAWGRDFLDEAVPLESGSHADVEKYDITSGQLAAVIDGNEVHLQQPEVFVGY
                     AGEKDAPTDIVLKHNGLHIDIQIDAESPIGSTDKAGVKDIVLEAAVTAIMDFEDSIAAV
                     DATDKVLGYHNWLGLNQGTLAEEVSKGGKTFTREQNDDRYFTARDGSELRLHGRSTMLC
                     RNVGHLMTNPAILDAEGNEVFEGIMDAVITAACAIPGTDLDNARRNSREGSIYIVKPKQ
                     HGPEESAFTNDLFADVEDLLNLPRFTLKVGLMDEERRTSVNLDACIEAIADRVAFINTG
                     FMDRTGDEIHTSLLAGPMFRKPKLKASLFMESYENNNVDAGLAHGLSGKAQIGKGMWAK
                     TDLLAEMVEQKIGQLRQGASTAWVPSPTGATLHATHYHMVDVYAVQEKLITDGRRDSIP
                     GILTVPVAAAKVGESDATWTAEEIQEELDDNCQSILGYVVRWVEQGVGCSKVPDIHDID
                     LMEDRATCRINSQLLANWLKHGVVTEEQVIEALQRMAAVVDRQNAGDDTYRDMAPDFEN
                     SVAWKAARDLVLLGTTQPSGYTEPILHARRLEFKELHGIA"
     CDS             10776..12065
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ICL"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_8"
                     /sec_met_domain="ICL (E-value: 3.5e-54, bitscore: 175.8,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNVGQPRTAAEIQKDWDENPRWANVTRDYTAEQVAELQGNVVEE
                     HTLATRGAEILWDAVNEPGDGYINALGALTGNQAVQQVRAGLKAVYLSGWQVAGDANLS
                     GHTYPDQSLYPANSVPSVVQRINNALSRADEIARVEGDTSIDNWLVPIVADGEAGFGGA
                     LNVYELQKAMIKAGASGTHWEDQLASEKKCGHLGGKVLIPTKQHVRTLNSARLAADVAN
                     TPTVVIARTDAEAATLLTSDVDERDHEFLTGERSAEGYYYVKNGIEPCISRAKSFAPYA
                     DMIWMETGTPDLELAKKFAEGVRSEFPDQLLSYNCSPSFKWSAHLDDDEIAKFQNELGA
                     MGFKFQFITLAGFHALNYSMFDLAHGYARNQMSAFVDLQNREFEAESRGFTAVKHQREV
                     GAGYFDRIATTVDPNSSTTALKGSTEEAQF"
     CDS             complement(12187..13278)
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MVDRGLPEKRVINALAKLGIRPDDSDITDESLRFSGHPRVQVRTA
                     SLPMRLDGSVRLADTTPDIMRSYGWDRMIYVTDLPLTTRRPVISQTVHRGTVTMLCLPA
                     FGLLRASEALRQELSRLLRGKPAGAGIREKFTESEDIEGGDADADVTRVIEGRGRGIRL
                     LLGMIAGNQPEQLFKVLTGCLAIAVATGAYGIFYGSMWQMSHTVSVPRMAVISLFAVGA
                     LSFWLIYHNGLWNRWPDRESDSVATWRARMDNRATLGTVAIAAVMIYSTVFLSLLVLSV
                     VIVDTNYFRSQVHDDPFPWGYAKLAWMTASLGTMAGAIGSSFDSDDAIREATYNRREHL
                     RRQITGLYEDKPPSRLRPQQRPR"
ORIGIN
        1 cccgcaccac ccgaaagggt ggtgcgggcc tctggacagg aggtgcctga ccccctggag
       61 gagggtcggg ctgcccgggg ttactggacc cggccgctgg ccttcttgta ggcgcggtag
      121 ttcttacggc cggcatgcac gaggaagaaa ccggcgaaca ggaggccgag gccggcgatc
      181 aggccgatga tgccgatcat ggagccgtcg tccgccatcg gggaggtcgt gtcggagttg
      241 acgccgaaac cgtagacgaa ggtaccgaaa ccggccaggg agaccaggat taggcccatg
      301 ccgatccagg tggcgctgcg gtgcagcgac gagtggggag catcgaacgt cgacggcacg
      361 aacccgtcga ggtaggcgag ctcattcgtg ggcgtccggg tctccagcgc ggtgttggca
      421 gacattcttt cctctttcat cggtgtggat gccggtaatt ctagatcacc gggtgccgca
      481 ccaccgaagc aacgggagca cgccgcggcg tccttccccc ttcacgggtg tggcagtgcc
      541 gtcagaacta gtcgtccttg cccttgaagg cggcgcgggc gcgctccttg gtgatcgcgg
      601 cgaccgcggt cagcgggatg ccggccgggc agacgtcggc gcactcgccg tagagggagc
      661 agggaccgaa ggtgccctcg acctcgtcga ccatggcctt ggcacgacgg ccacgctcca
      721 tgcggcccag cggggacagc gtgaggtgga ccagcttcgc gccagtgaac aggtgcgcgg
      781 caccgttcgg gcaggcggcc acacaggcac cgcagccgat gcaggcggcg tggtcgagcg
      841 cgagctcggc gtcgtggtgg ttcaccagga ggtggtcggc gtccggagcg gtaccggcga
      901 cgatcgagac gaagccgccc ttctccatga cacggtccag cgcggaccgg tcgacgacca
      961 tgtccttgat gaccgggtag gcggcggagc gcatcggctc gatcttcagg gcgtcgccgt
     1021 cagagtagct gaacaggcgc tgctggcagg caggcttgtt ctggtccggg ccgtgcgggc
     1081 gaccgttgac caggaggcca caggtaccgc agataccctc gcggcagtcg gaggcgaagg
     1141 cgaagggttc cttgcccgcc tcgacgtagc tggagttcac gtggtcgaga agctccagga
     1201 tggacatgga ctcgacggcg tcgggcacgt ccacggactc gaagtgtccc tgggcattgc
     1261 ggtccgcctg ccgccagatt tcaagatgca gtttcattac ttgtagttcc ttgtcatcag
     1321 cgggatgcgg tcgaagtaca gcggctcaga gtgccggatg aacttctcgt cgcccgcggg
     1381 ctcccaggcg gagacgaagc accagttgtc gtcgtcgcgc ttcgcctcgc cttcctcgtc
     1441 aaggtggtcc tcacggtagt gggcgccaca ggactcgtca cggtccaggg cgtcgacaca
     1501 catgagctca ccgaggtcca ggtagtcggc cacgcggatc gcgtactcga gctgctggtt
     1561 catctcggcg gtgccgccgg ggacgaagac gttctcccag aagtccttgc ggaccgcgcg
     1621 gatctcgtcg atgccctcct gcatgtcttt gacgttgcgg gccacaccac agcagcggta
     1681 gaggatctca ccgagctggc ggtggtagta ctccgcaccg tgcgggttcg ggccacggat
     1741 gttgaggatg ttgttgagac ggtcctcggt gcgcttgagc gctgccttcg cggcggcgga
     1801 gtcctcgtcc gggatgtccg tacccagcag cggagccagg tagttcggga tggtgaaggg
     1861 cagggtgaac cagccttcga ccgaggagga cagcagggag ttcgcaccca gtcggttcgc
     1921 accgtggtac atccaggaag actcaccgga gcagaacaga cccgggatcg aggtcatctc
     1981 gtggaagtcg gtccacagac cacccatggt gtagtggcag gtcggggcga tgcgcatcgg
     2041 ggtcttgtag gcgtcgtctc cgatggcctc ctcgtacatc tggatgaggt tggagtaccg
     2101 ctcgcggatg acgtcctcgc cgaggttctt gatggcgtgg gtcaggtcga ggtagaccga
     2161 gttcttcttc gggcccacac cgtagccggc gttgatctgc tgcgcgttcg cacgggaggc
     2221 gatgtcacgc gggaccaggt tgccgaaggc cgggtagcga cgctcgagga agtagtcgcg
     2281 ctcgtcctcg gggatcgtca tcggatcccg ctggtcgtcc ttcttcttcg gggtccagat
     2341 gcggccgtcg ttacgcagag actcggacat caggatcgtc ttggactgcc agtccgagtt
     2401 gaccgggaga ccggtcgggt ggaactgcac gaaggacggg gacgccatgt aggcaccctg
     2461 ctcgtaggca cgcatgatcg cgctggcgtt ggagttcttg gccagcgtgg acatgtggta
     2521 cacgttgccg taaccgccgg tggcgaagac ggtgacgtga ccggtgtgga tgctgagctc
     2581 accggtgatg atgttgcggg tgacgatgcc cttgcagacg ccgtcctcca cgatgacgtc
     2641 ctggacgtcg gagtgggtga agatctccac gttgccggca ccgatctggc ggtacagggc
     2701 agaggtggtg gccagctgca gctgctgacc ggtctgacca cgggtgtaga aggtgcggga
     2761 cacctgcaca ccaccgaagg aacggttggc cagggttccg ccgtactcac gggagaacgg
     2821 ggcgccgatg gcgttcatgt ggtcgatgac gcgaccggac tccatggcga gacgccagca
     2881 gtcattctcc cggcaccggt agtcgccgcc cttgacggtg tccttggtgt ggttgtaggt
     2941 cgagtcgttg tccaggcgct tggcgcgcga ggagttgacg ccaccctgcg cggcgatgga
     3001 gtgcgcgcgg cgggggctgt cgtggtaagt gaagaccttc acgttgtagc cgagctcacc
     3061 gagggcggct gcggctgcgc caccggcgag gccggtgccg acgatgagga ccttgaactt
     3121 cgcacggttc agcggggaga ccagcttgaa gtgctccttg tcgaactgcc actgctgctg
     3181 ctgtgacacc tcgtgcgggg cgttgtcacc gatgaccttg ccgacggtca cgccgtcgac
     3241 ctgggactcc ggggcctgga atgctgccag tgcctcgtcg tagttgaagt cagcggtctg
     3301 gttgtgcggg tggggcttgc tcatacccat tgttgtctct tctccttttc cagatccgct
     3361 agctaccgaa gccgcacagg acggccaccg ggatcgagat gttgccgatc atgacgatgg
     3421 ccgggagcag gtacgcgatc cacaggatga cctggcgggt gcggtgaccc gtgattccga
     3481 ggtcggagga cgccagccag attccgtgcg aggcgtgcag gaagagcacg accatgcaga
     3541 ggatgtagat gatggcgacc caggggcggt tgaaggactc gaccaggttg ccgtaggcct
     3601 caccgtgctc gaaggcgtcg gtggcgacgc ccttgccgat ggtcaggtcg aggatgtgga
     3661 agatgatgaa gagcagcagc accgcaccgg tgcccagcat ggagctggcg gtgaaggtgt
     3721 tgaagttctt caccttgccg aagcgcttct cggaaccacg ggactgcttc gaccgagcct
     3781 ccagagcgaa ggcgcagtac acgtgcagca cgaggcagat aatgaggacg acgcgcagga
     3841 tccacagcac cgtctcatgg gggaagacag gctcacccat gcgacgcagg aaatctgcgt
     3901 agtcgttgaa gtgtccctca ccggtgtaaa ccttcaggtt tcccaccatg tggaacagga
     3961 cgaaaagaac gaagatgatg ccagtcacgg ccatcgtcag cttcatcgcc caggacggga
     4021 aatcgggcct ttcccgcagc ggtttaatgt tcagtttccc gtgctccagt gcgacgggat
     4081 catcgtattt aacagtcatg gcacctccag tgtcagtgac actgtacgac tgccagagtg
     4141 gcaaacacta actgaccccc ctcaccgtga aaaagatcac agcgctgcag tacgcccgta
     4201 atgtgaacac ctcgttatgc aggtcaaaca cagattctgc gcgttttata agtgaggttc
     4261 gcctgtcctg acccgcctcg cagaatctgc gcagtcgctc acgacgcgca atatcgttat
     4321 atccgaatca tttttcaacg aagacgacat cggcggacgg tacagactcc gacaggccgt
     4381 cctcctcgga caccagcgtg gtcgtcccct cgacccgcac cggggccgaa ccgatgacca
     4441 cgtcctgtcc gagaacggtc accggaccga cgagaccctc gccgccgtcg acgatctgga
     4501 gctccacggc gtccttctcc acggacaccc ggatctggta gccctgcagg gtcacgttgt
     4561 actcgagctc gtcccagccc tccggcagac gcgggtcgat gctgaaccgg ccgtagtcgt
     4621 cacggaagcc gccgaacccg aagaccagcg cactccacac accaccgcag gacgcgatgt
     4681 gcgcgccgtc ggcactgttg ccgtgcaggt tctccaggtc gaggaagaga ccgcgcagga
     4741 agaatctcat cgcggtgtcc cggaagccga gctccgcggc catgatggac tgcaccaccg
     4801 ccgagaggga ggagtcgccc gtcgtcagcc ggtcgtagta ggcgtagtcg cgcttcttca
     4861 cctcggtcgg catgtcgcgt ccctggagga acagggcgag caccacgtcg gcctgcttga
     4921 gtacctggta ccggtagatc gtcagcgggt ggtagtgcag cagcagcgga cgcttcgccc
     4981 ccaccgccgg gtcgtcgagg ttccacagct gccggttgag gaactggtcg tcctgcgggt
     5041 ggatctgcat ccgctcgtcg aaggggatgt acatcgcctc ggcggcgcgg tcccagaggt
     5101 ccagttcgtc ctcggacagg ccggtgcggt cggcgaggtt ctggaaggcc tccggacgct
     5161 cactgcgcat ctgccgggcg acatcggcgg cgacccggag gttgtactgc gccatgacgt
     5221 ttgtgtacag gttgttgttc accactgtgg tgtactcgtc ggggccggtc accgagtgga
     5281 tctggaactt ctcccccgtc gtttcgaaga accccaggga catgaagaac cgtgccgtgc
     5341 cgacgaggat gtcgatgccc tcgtccagca ggaattccgc gtccccggtg gcgtagacgt
     5401 acttcatcag ggcgtaggtg atgtccgcgt cgatgtggta ctgcgccgtg ccggccgcgt
     5461 agtaggcact ggactcatgc ccgttgatcg tgcgccacgg gaacaggaca ccgtcatggg
     5521 agagctctcg ggcacgctcc ttcgcctgcg gcagcatgag gtagcggaac cgcagggcgt
     5581 tccgggagaa ctgcgggttc gtgtaggtga ggaacggcag ggcgtagacc tcggtatccc
     5641 agaagtagtg gccaccgtag cccgacccgg tcagcccttt ggccggcaca ccctgggtct
     5701 ccgcacgggc ggacgcctgg atcagctgga agagattcca ccgcaccgcc tgctgcagtt
     5761 cggggtggcc cgggatccgg acgtcggacc gccgccagaa cttccccagc cactccgcct
     5821 ggttggcctg cagggtgcgg tagccgacct gacgggcgcg gttgatcgtc cgggcgcagc
     5881 ggaaggccag ttcctcggcg gagacgtggc gcgaggagtg gtaggagacg aacttctcga
     5941 gccgcagtcg caacccgcgg gtgccgtcga cgtggtagac cacgcgggcc acatcgtcgc
     6001 gcatctcggt gtgcatctcc acaccgccga ccgcgtcaga ggatgccgga gcacccgagc
     6061 cgccggtccc ctgtgcctgg gtcacgtcga ggacatggtc catgctcacc gcgaccgtca
     6121 tgccggagtt cgtcacccgg tagccgagcg tcacccgctg gtcctcggaa ctggcgcggt
     6181 aggtcggctg gaacacccgg ccggcgatct tctctgcctt gcgggggtcg ccaccgccgt
     6241 tgacgtccgc ggcgtgggcg taggcgcggt ccgctgcccc ggaggacgcc gcgtaggtgt
     6301 cgaggatcga ggagaactcg tcctccccgt cctggcggtt gagtatctgc gaggagatga
     6361 cgaccgcggc gtccgagtcg aggagctcga cctcgaggct catcagcgcg agatgccgct
     6421 cctggaagga gaccatccgg tcggtgacga cgcggacgcg cttgccggac tgggtacgcc
     6481 agatgaaact ccggcgctcc accccctcac ggaagtcgag ggtgcggccg tagtcctcga
     6541 cctccgcgac accgaggcgc agcggttcat cgtcgatgta cagccggatc ggcttggcgt
     6601 ccggtacctg gacgatggtc tggccctcgc gggcgaaacc gtaggcgtcc tcggcatgct
     6661 cgatgttcca cgtctcatgg acaccgttga tgaaggtgcc gtgctcgtgg gagtcgcgac
     6721 cctccggcgg gttaccgcgc agacccatgt atccgttgga gagggcgaag acggtctccg
     6781 acaggccgag ttcggcgtcc gaccggacgg gacggcgctc atgccagccc cactcgtcga
     6841 ccgggtggtt ggtccggtcc accagttcca gcgggtcgac gtcgtcgagg tgcacgtcgg
     6901 tgcggtagcc cgggggaaag tagtcggtgg gatcggccgg tccgccaccg tcaccgacgg
     6961 ggcggttcac gacggacgcc acccggcgac gctgcgccag gaactcctcg aggtggtcgg
     7021 tccggtcgtt agagtcggtc acggaatgtc ccttcggtcg gcttcagtgt tgtcttcagg
     7081 attgatcagt ggttcagcgt acggcagagg agccgtcgga ggtgccgagc cggtcgacga
     7141 ggtcggcgag gtcggcgacg acgacgtccg ccccggcgtc cttcagtgcc tgtgccccgg
     7201 caccgcggtc gacgcccagg accagtccga agtcgccggc ggcacccgcg gcgacgccgg
     7261 aggtggcgtc ctccacgaca accgccccgg tcgacggaac accgagcagt tccgcaccgt
     7321 agctgtaggt gtccggggcc ggcttgccgg gcagcccctc ggcggcggcg acattgccgt
     7381 cgatgatgac ctcgaagcgg tcgatgagac cggcggcggt gaggaccggg cgggcgttct
     7441 tcgacgagct caccacggcg acccgcgtgg tggtgcccgg ggcggtgagc gcgtcgagca
     7501 gggcgacgga cccgggatag gccgtgatgc cccggtcgag cagggccagg aaatcggagt
     7561 tcttcagcag gccgagaccg aggacggtct cgtcggtggg ggcgtcctcc cccttctccc
     7621 cctcccacgc cggatcggac cggtcggcgg gcagcgtgat cccgcgggac gccagcaccg
     7681 cggccacccc ctcactgcgc ggacgtccgt cgatgtggtc gaagtagtcc tgctcggtgt
     7741 acggggcgac accacgttcg acgaagtacc tggtgaacac cacggaccag gcctgtcggt
     7801 ggagatcggc ggtcggggtg atgacgccgt cgaggtcgaa gagcacggcg tcgaaggcgg
     7861 cgaggtcagg cagggcgtca ggcaggtctg ctgtcattcc accatcgtag gtggcccgcg
     7921 gacgccgcgc gcggtgtagc agcatcatga aaaccgcccg ggtgtcatga gaaactcgcg
     7981 cataaggccg ttgaaccggg attttcgcat gacggcgggg cagaactcat ggcggtcacc
     8041 cgggacaggg ccgcggaaag ccggaaacgg cccgccccgg ggagggacgg gccgtcacgg
     8101 tgatgaaagg tgcgcggcgg tgtcaggcga tcgccttagg cgataccgtg cagctccttg
     8161 aactccaggc ggcgggcgtg gaggatcggc tcggtgtagc cggagggctg ggtggtaccg
     8221 agcaggacga ggtcacgggc ggccttccag gcgaccgagt tctcgaagtc gggggccatg
     8281 tcgcggtagg tgtcgtcgcc ggcgttctga cggtcgacca cggcggccat gcgctgcagg
     8341 gcctcgatga cctgctcctc ggtgacgaca ccgtgcttga gccagttggc cagcagctgg
     8401 gagttgatgc ggcaggtggc ccggtcctcc atgaggtcga tgtcgtggat gtccggcacc
     8461 ttggagcaac cgacaccctg ctcgacccag cggaccacgt agcccaggat ggactggcag
     8521 ttgtcgtcca gctcctcctg gatctcctcg gcggtccagg tggcgtcgct ctcgccgacc
     8581 ttggcggcgg cgaccgggac ggtgaggata cccgggatgg agtcgcggcg accgtcggtg
     8641 atcagcttct cctggacggc gtagacgtcg accatgtggt aatgggtggc gtgcagggtc
     8701 gcaccggtcg gggacgggac ccacgcggtg gaggcgccct gacgcagctg gccgatcttc
     8761 tgctccacca tctcggcgag aaggtcggtc ttggcccaca tgcccttacc gatctgggcc
     8821 ttgcccgaga gaccgtgggc caggccggcg tcgacgttgt tgttctcgta ggactccatg
     8881 aacagggagg ccttgagctt cggcttacgg aacatcgggc cggccagcag cgaggtgtgg
     8941 atctcgtcgc cggtacggtc catgaagccg gtgttgatga aggccacgcg gtcggcgatg
     9001 gcctcgatgc aggcgtccag gttgacggag gtgcggcgct cttcgtccat caggccgacc
     9061 ttgagtgtga agcgcgggag gttgaggagg tcctcgacgt cggcgaacag gtcgttggtg
     9121 aaggcggact cctccggacc gtgctgcttc ggcttgacga tgtagatcga gccctcgcgg
     9181 gagttgcggc gggcgttgtc caggtccgtg ccggggatgg cgcaggcggc ggtgatgacg
     9241 gcgtccatga tgccctcgaa gacctcgttg ccctcggcgt cgaggatggc ggggttggtc
     9301 atcaggtgac cgacgttgcg gcacagcatg gtggagcggc cgtgcaggcg gagctcggag
     9361 ccgtcacgtg cggtgaagta gcggtcgtcg ttctgctcac gggtgaaggt ctttccgccc
     9421 ttggagacct cctcggccag cgtgccctgg ttcaggccga gccagttgtg gtagccgagg
     9481 accttgtcgg tggcgtccac cgcggcgatg gaatcctcga agtccatgat ggcggtcacg
     9541 gcggcctcca ggacgatgtc cttgacaccg gccttgtcgg tgctgccgat cggggactcc
     9601 gcgtcgatct ggatgtcgat gtgcagaccg ttgtgcttca gcacgatgtc ggtcggggcg
     9661 tccttctcac cggcgtagcc gacgaagacc tcgggctgct gcaggtggac ctcgttgccg
     9721 tcgatgacgg cggcgagctg gccggaggtg atgtcgtact tctcgacgtc ggcgtgggag
     9781 ccggactcca gcggcacagc ctcgtcaagg aagtcacggc cccaggcgat gaccttgtcg
     9841 ccgcggacct tgttgtagcc cttgcccttc tcggcgccgt tctcctcgga gatgacgtcg
     9901 gtgccgtaca gggcgtcgta gagggaaccc cagcgggcgt tcgcggcgtt gatcgcgaag
     9961 cgggcgttga ggatcggcac gaccagctgc gggccggcgg tggtggcgaa ctcggcgtcc
    10021 acgttctcgg tgcggatctc gaagtcctcg ggctggtcga cgaggtagcc gatctccttg
    10081 aggaaggcgg tgtacttctc ggcgtcctgc gtgcccgggt tctgcgtgta ccactcgtcc
    10141 agcttcgcct gcaggtcatc ccgcttggcg agcagctcac ggttgcgcgg ggtgtgcttg
    10201 gcgacgatgg ctccgaagcc ctcccagaac ttctcctggt ccaccccggt gccgggcagg
    10261 acctcgccgt tgacgaaatc gtagagggtc ttggcgacct cgagaccacc ggcggtgatg
    10321 cgctgcgtct gctgtgtcat ggaaactcct tcagttcaca tatcgacttg tccgcaatac
    10381 ggacaccaga ctaggtgagc catgtcaccg aggggagtca tccgtgctcc agggaacgac
    10441 ccaccacccc cggcaccacc ccgttccaga ctggcgaacc cgggttcact tgtgtactgg
    10501 agcgtgccct tacgtgatgc acgtcgcacg tcaccgctgg accacgcgtt ttttgaccat
    10561 taggtgagat gaacaatgtc agtatctgag acccaagaaa acggtacgat cgtactaccc
    10621 ccgccgtggg ctggatcacg tatttgcttt gacgtgccgt tttccccctg tattctcgag
    10681 cccagcagat ccggccgggg agcagccgcc cccggggtag ccggaatcag cgttgtaacc
    10741 gccatctcca ccacttaagg gagtgtgttt aacacatgtc gaacgtcgga cagccgcgta
    10801 ccgccgccga aatccagaag gactgggacg agaacccccg ttgggccaac gtcacccgcg
    10861 actacaccgc cgagcaggtt gccgagctcc agggcaacgt cgtcgaggag cacaccctcg
    10921 ccacccgcgg tgccgagatc ctctgggacg ccgtgaacga gccgggcgac ggctacatca
    10981 acgccctcgg tgccctgacc ggtaaccagg ccgtccagca ggtccgcgcc ggcctgaagg
    11041 ccgtctacct ctccggttgg caggtcgccg gtgacgccaa cctctccggc cacacctacc
    11101 cggaccagtc cctgtacccg gcgaactccg ttccgtccgt ggtccagcgc atcaacaacg
    11161 ccctctcccg cgccgacgag atcgcccgcg tcgagggcga cacctccatc gacaactggc
    11221 tcgtcccgat cgtcgccgac ggtgaggccg gcttcggtgg cgccctgaac gtctacgagc
    11281 tgcagaaggc catgatcaag gccggcgcct ccggaaccca ctgggaggac cagctggcct
    11341 ccgagaagaa gtgcggccac ctgggcggca aggtcctcat cccgaccaag cagcacgtcc
    11401 gtaccctgaa ctccgcccgc ctcgccgccg acgtcgccaa caccccgacc gtcgtcatcg
    11461 cccgcaccga cgccgaggcc gccacgctgc tgacctccga cgtcgacgag cgcgaccacg
    11521 agttcctcac cggtgagcgt tccgccgagg gctactacta cgtcaagaac ggcatcgagc
    11581 cctgcatctc ccgtgcgaag tccttcgctc cgtacgccga catgatctgg atggagaccg
    11641 gtaccccgga tctcgagctc gccaagaagt tcgccgaggg cgtccgctcc gaattcccgg
    11701 accagctcct gtcctacaac tgctccccgt ccttcaagtg gtccgcccac ctggacgacg
    11761 acgagatcgc caagttccag aacgagctgg gcgccatggg cttcaagttc cagttcatca
    11821 ccctggccgg cttccacgcc ctcaactact ccatgttcga tctggcccac ggctacgccc
    11881 gcaaccagat gtccgccttc gtggacctgc agaaccgcga gttcgaggcc gagtcccgcg
    11941 gcttcaccgc tgtcaagcac cagcgcgagg tcggcgccgg ttacttcgac cgcatcgcca
    12001 ccaccgtgga cccgaactcc tccaccaccg ccctcaaggg ctccaccgag gaggcccagt
    12061 tctaggaacc tccgggcctg cgcctgacgt tctgaactga ctgaccaccg cccgtcctgc
    12121 ttcgtgcagg acgggcggtg gttttctgtg tggcaggcgg cactcccccg tgccccgtca
    12181 ccccctctac cgcggacgct gctgaggacg cagccgtgac ggtggcttgt cctcgtagag
    12241 tcccgtgatc tgacgacgca ggtgctcacg ccggttgtac gtggcctcgc ggatggcgtc
    12301 atcgctgtcg aaactggagc cgatcgcccc cgccatcgtg cccagcgacg ccgtcatcca
    12361 ggcgagcttc gcgtagcccc acgggaaggg gtcgtcatgg acctgggacc ggaagtagtt
    12421 cgtgtccacg atcaccaccg agaggacgag cagcgacagg aagacggtcg agtagatcat
    12481 caccgcggcg atggccaccg tgccgagtgt ggcgcggttg tccatcctgg cacgccaggt
    12541 cgccaccgag tcgctctccc ggtcaggcca ccgattccac agtccgttgt ggtagatcaa
    12601 ccagaaggac agcgccccca ccgcgaacag gctgatcacc gccatacgcg gtacagacac
    12661 cgtgtgcgac atctgccaca tcgagccgta gaagatgccg taggcgccgg tcgccaccgc
    12721 gatggccagg cagccggtga ggaccttgaa cagctgctca ggctggttgc cggcgatcat
    12781 cccgagcagc agtcggatgc cgcgtccccg tccctcgatg acgcgggtga cgtccgcatc
    12841 ggcgtcacca ccctcgatgt cctcactttc ggtgaacttt tcgcggatac ccgccccggc
    12901 gggtttgccg cgcagcagac gactgagttc ctgacgcagc gcctcactgg cccgcagcag
    12961 accgaacgcg ggcagacaca gcatggtcac cgtgcctcgg tgcaccgtct ggctgatgac
    13021 cggccggcgc gtcgtcaacg gcaggtcggt cacgtagatc atccggtccc agccgtagga
    13081 cctcatgatg tccggggtgg tgtccgccag gcgcacactg ccgtcgaggc gcatgggcag
    13141 ggacgcggtg cggacctgca cccgcggatg accgctgaag cgcaggctct cgtcggtgat
    13201 gtccgagtcg tcgggacgga ttcccagctt cgccagggca ttgatgacgc gcttctcggg
    13261 cagcccgcgg tcgaccatca cgccgacgac ggtgacatgc tcctctgcat actcgtcggc
    13321 atgatcctca gcggggaccc cgttctccgg cacctctgac atggccagaa tcgtaccctc
    13381 accacggcga aggacgcatc aacgccgcgc acggcagaac acatatccgg gcacataaca
    13441 gagccccgga cacagggact gtgaccgggg cggtggtgca ggggaaccta caggttgatc
    13501 atgtgacccg cgatgccctc ggccgcttcc ttaatggcct ccgacagggt cgggtgggtg
    13561 tggacgttgc gtccgatctc ctcggtggtg aggtcgaaac gctgcgccag agtgagctcc
    13621 ggcagcagct cggagacatc cgggccgacc atgtgggcac cgataagctc gccgtactcg
    13681 gcgtccgcga tgatcttcac gaaaccgacg ccctcgttga ggccctgggc cttaccgttg
    13741 gcggagtagg ggaaggtcgc gaccttgata tcgcggccgg actcctcagc acgcttgcgg
    13801 gcggcgtcct cggtgtaacc gaaggacgcg acctgcgggg tacagaaggt ggcccgcggc
    13861 atgttcatgt agtcgccgag ctcctgggtc tcgacgccgg cgatggtctc cgcggcgacg
    13921 acaccctgcg cctcggcgac gtgcgcgagc tggagcttcg cggtgacgtc accaatggag
    13981 tagatgtgcg gcacgttggt gcgcat
//
