LOCUS       NZ_LN913000.1          24841 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LN913000.1 Mediterraneibacter massiliensis strain
            Marseille-P2086, whole genome shotgun sequence.
ACCESSION   NZ_LN913000
VERSION     NZ_LN913000.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:18:09
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 456736
            Orig. end    :: 481577
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24841
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[466736:471577]"
                     /cutoff="2000"
                     /detection_rule="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /neighbourhood="10000"
                     /product="Hydroxy-L-proline2proline"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14841
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /neighbourhood="10000"
                     /product="Hydroxy-L-proline2proline"
                     /protocluster_number="1"
     cand_cluster    1..24841
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /kind="single"
                     /product="Hydroxy-L-proline2proline"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24841
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Hydroxy-L-proline2proline"
                     /region_number="1"
                     /rules="((PFL_proline or cds(PFL-like and Gly_radical)) and
                     Radical_SAM and P5CR_dimer and F420_oxidored)"
                     /tool="gutsmash"
     CDS             2378..3544
                     /locus_tag="ctg3_410"
                     /transl_table=11
                     /translation="MKEEKIAGIALRRKGIVLLKQPATGGECCDVELFLNEGHFLLIDE
                     STNHLDSDARKKVSAYLRKKKGFILVSHDRRFLDGCVDHILSLNRADIKVQSGNFSSWM
                     ENFAWQQKAEISQNERLKKDIRRLQKAAKRSAVWSERIEASKIGAADKGYVGHKAAKMM
                     KRSKTMEKRQQQSMEQKAALLKNAETIDTLKLYPIEYHTNLLAAFSDVAVLYDGRQICR
                     SVSFQVREGERIFIEGKNGSGKSSLLKLLSGHPIEHTGTLTIGSGLVISYVPQDTSHLM
                     GTLAVFSEENGLDESLFKAVLRKMDFERVQFEKDMKDFSEGQKKKVLLAKSLCEKAHLY
                     VWDEPLNFIDVYSHRQIEQLIESFSPTMLLVEHDIAFREATATKTIKL"
     CDS             3640..4587
                     /locus_tag="ctg3_411"
                     /transl_table=11
                     /translation="LSEDKEKEYRTLRPWQGFLVIVIAAVYLFLIAPKFIGRFGRIGSL
                     LGEAGFLLLSVTAVWIWKGDFKVVFPFRKPCFTTMAGVGILWMGMMLLISVATMLLQLF
                     FPEVYFETGIETALGYTGIPVLLLTAILAVSPAICEEALFRGVFVNSLLPLKKKWLIIL
                     ISSVIFGLFHGSPAKFVPTALGGAALGFVFLETGNLFYSCLYHFINNMSSVIVLAAMGD
                     IYKYMARTGAFSEMQQIPLTSIGLSVMMSAAAPACLYIGNYLLHSQTEGYRETLFPRRK
                     PGIVISLIAVSGILFVSGVYLFLYGMIEIGLPAF"
     CDS             complement(4657..5844)
                     /locus_tag="ctg3_412"
                     /transl_table=11
                     /translation="MSNLNATPSANRLHIGIFGRRNAGKSSIINALTGQDLAIVSDIQG
                     TTTDPVLKAMELLPLGPVVLIDTPGLDDEGALGALRVKKAFQMLNKTDIAVLVVDAGVG
                     LTEKDREILRKIQEKEIPYVIAYNKCDRTPLSPAAEENVIHVSAATGKNIHQLKELIAR
                     CAATENIDKKIVGDLLSPGDFVVLVVPIDSAAPKGRLILPQQQTIRDILDSGAVAVTVR
                     DTELEDTLRRLDRQPALVITDSQVFEQAAAVTPPDIPLTSFSILFARYKGDLKILTEGA
                     AVLDELKENDTVLISEGCTHHRQCNDIGTVKLPNWIQKHTGRQLRFAFTSGTQFPDDLS
                     PYQLVIHCGGCMLNDREMKYRLRCAKDQGIPITNYGTAIAHMKGILKRSTSIFSL"
     CDS             complement(5907..7328)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_413"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-10, bitscore:
                     36.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDVHSKHAEDFINHEEILETLAYADENKHNAALIDTLIEKAKKR
                     KGLSHREASVLLACDLKEKNEEIFRLAEQIKKDFYGNRIVMFAPLYLSNYCINGCTYCP
                     YHAKNKHIARKQLTQEEIRREVIALQDMGHKRLALEAGEDPIRNTMDYYLDSINTIYSI
                     KHKNGAIRRVNINIAATTVDNYRLLKEAGIGTYILFQETYHKESYLKLHPTGPKHDYAY
                     HTEAMDRAMEGGIDDVGIGVLFGLDKYRYEFAGLLMHAEHLEAAFGVGPHTISVPRLRD
                     ADDIDSSSFKNGIDDDTFAKLVACIRIAVPYTGMIISTRESQKTRERVLHLGISQISGG
                     SRTSVGGYCEPEPDTEKSEQFDVVDTRTLDEVVCWLMEMGYIPSFCTACYREGRTGDRF
                     MSLCKSGQIQNCCHPNALMTLKEYLMDYASPKTKAIGDALIEKEVFNVPNEKARSVVLE
                     NLRLIEQDNRRDFRF"
     CDS             complement(7365..8414)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_414"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-09, bitscore:
                     33.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNMKILIDKLARAHTLSKDEWVQLIRGRTKENSEYLFLLARKFR
                     EKYYGHDIYIRGLIEFTNYCKNDCLYCGIRRSNKNARRYRLKKEEILSCCRTGYALGFR
                     TFVLQGGEDGYYTDEVMEDIVSTIHSSYPDCAITLSIGERSLESYQRLFDAGASRYLLR
                     HETFDASHYARLHPAALSAANRQKCLWDLKEIGYQVGTGFMVGSPFQTPENLADDMLFL
                     KRLDPHMVGIGPFIPHQETPFAREQAGTLSLTLFMLALIRVMLPKVLLPATTALGTIAP
                     DGREQGILAGANVVMPNLSPQDVRKDYLLYDNKICTGDEAAECRQCLERRMNSIGCRTV
                     VARGDSLNI"
     CDS             complement(8433..8681)
                     /locus_tag="ctg3_415"
                     /transl_table=11
                     /translation="MDTRIALIGIVVNSNEAIDDLNHLLSQYSAYIIGRMGIPYREKGI
                     SIISITLDAPSDVISALSGKLGMLPGISTKTIYAKPK"
     CDS             9080..9985
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_416"
                     /sec_met_domain="Fer4 (E-value: 2e-06, bitscore: 22.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Radical_SAM (E-value: 6.7e-26, bitscore:
                     87.0, seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00047, bitscore: 16.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLITDIQKYSIHDGDGIRTTVFFKGCALRCQWCHNPETQNTGRE
                     LLCHTESCVGCGACVEICPAHAVCIQEGKAWTDREICTACGRCTEVCNLNLREIAGKEY
                     TVDDLVKELKKDEMFYEESGGGVTLSGGEVMLADMDFVEAVAKRLKAAGIHVAIDTCGY
                     APRANFERLLPFVDLFLYDIKTMDTAVHKKYMGFGNEQILENLEYLNHAGADIYIRIPT
                     IKGVNADEKSMRAILSYLKEKQIRVLQINLLAYHNTGSAKYARLGRAYEGDALCAPSGE
                     EMQTFADLFQEAGYKVKIGG"
     CDS             10001..12376
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: PFL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_417"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-34, bitscore:
                     112.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 3.4e-228, bitscore:
                     754.8, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEERGMNERIKKLRKVSLDTEAHIDLERAKSETRTYQKYEGEISV
                     PELRAQVLKEYFATKTLYIGEGELIVGEKGDSPQAAPTFPELCCHTVDDMRVMNDRELI
                     SFKVREEDYQVQEEVMIPYWEKRSIRHKILRQMTPEWKAAYESGIFTEFMEQRGPGHTV
                     GSVKIYEKGFLDYKKEIEEAIDRLDFLNDKEAYDKKNELEGMKIACDAIMVLGERYAAY
                     ARELAQTERDETRKAELLQIAANCDVVPAHRPQTYWQAIQMYWFVHLSVTSELNPWDAY
                     SPGRFDQHLNPFYQRDIEAGILDEKRALELLECLWVKFNNQPAPPKVGITLKESGTYTD
                     FANMNTGGITPDGENGVNDVSYLILDCMDEMKLLQPSSNVQISKKTPQKFLKRACEISR
                     KGWGQPAFYNTEAIIQELLNAGKSLEDARRGGTSGCVETGAFGNEAYILTGYFNLPKIF
                     ELTLHNGYDKVAGKQLGPKTGDVTEFTTYEEVFEAYKKQIAYFLDIKIKGSNVIEKIYA
                     EHMPVPFLSVITNDCISKGKDYNSGGARYNTKYIQGVGIGTITDCLAAVKYNVFDEKKF
                     TMAELLEALEDNFEGHERILNLVRNKTPKYGNDDDYADDIMKAVFAYYREQVTGRPNML
                     GGTYRINMLPTTCHVYFGEVMMASANGRLAHKPVSEGISPEKGADINGPTAVVKSCSKM
                     DHLQTGGTLLNQKFTPSVVAGEEGLDQMANLVRTYFNMDGHHIQFNVIDKETLIEAQKH
                     PDDYKDLIVRVAGYSDHFRNLSKALQDEIIERTEQSFH"
     CDS             12455..12724
                     /locus_tag="ctg3_418"
                     /transl_table=11
                     /translation="MSEVRQHIVFHGRVQGVGFRYTAKYLAQSLELTGWVKNEWDGTVT
                     MEIQGREALIHKLLKGLNNGHFISIEWMDTIELPLEEERGFYVK"
     CDS             12748..13542
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: P5CR_dimer"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: F420_oxidored"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:NADP oxidoreductase coenzyme F420-dependent
                     (Score: 71.1; E-value: 3.1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_419"
                     /sec_met_domain="F420_oxidored (E-value: 3.3e-21, bitscore:
                     71.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="P5CR_dimer (E-value: 1.2e-41, bitscore:
                     136.6, seeds: 951, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGFIGTGNMAGAIMGGIIKKGIFKPEEIMGSDISEQGRKRVQD
                     MYGICVTGDNREVASKAEVLLLSVKPQFYAETIAEIKDVVAKEQIVITIAPGKTLDWLR
                     EQFGKEVKIVRTMPNTPAMVGEGMTAACPNEFVTEEEKAYVQKILEAFGKVEIIPERLM
                     DAVVSTSGSSPAYVFMLIEAMADAAVADGMPRPQAYKFAAQAVYGSAKMVLETGKHPGE
                     LKDMVCSPAGTTIEAVRVLEEKGFRSAVIEAMKTCAEVSRKM"
     CDS             13544..14146
                     /locus_tag="ctg3_420"
                     /transl_table=11
                     /translation="MDKEEKKKSVKTRIVSAAWQLFYEKGYDQTTVDDIIALSGTSKGS
                     FYYYFSTKDELLGTLSNVLDDFYEELAARMEPSMNSFDKLLYLNEKAHEMIEKKIPLDL
                     LTSLYSTQLTFKGNRHLLDKNRVYYQLITEIAEEGQKRGEIRTDKPVSEIVRYYSLCER
                     ALITDWCLNQGSYSLHAYTKEYMPVMLAYFRQKSEEA"
     CDS             14146..14841
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_421"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-22, bitscore:
                     76.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIQGLQKLTLLDYPGKVACTLFTAGCNFRCPFCHNASLVTHVDR
                     KNDIPEEEVLAFLKKRRGLLDGVCITGGEPLLQPDIEVFIRKIRDLGYLIKLDTNGSNI
                     LLLKRLAEEGLLDYVAMDIKNAPDKYGVTIGIEEYDLENILQSVEFLLSGSIPYEFRTT
                     VVREFHKREDFAAIGRWIRGAEKYYLQSFQDSGDLIAPGLRGYTKEIMEQALEIVRKNV
                     PNAELRGVE"
     CDS             14993..17401
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NRDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_422"
                     /sec_met_domain="NRDD (E-value: 7.4e-190, bitscore: 627.7,
                     seeds: 337, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQVTKRDGKIAEFNLVKISEAIRKAFEAQEKQYNQDIIDLLALK
                     VTADFEPKIKDELVSVEDIQDSVESVLIKAGYADVAKGYILYRKQREKIRNLNSTLLDY
                     KEIVDSYVKITDWRVKENSTVTYSVGGLILSNSGAITANYWLSEIYDEEIGKAHKNADI
                     HIHDLSMLTGYCAGWSLKQLIQEGLGGIPGRITSAPAKHLSVLCNQMVNFLGIMQNEWA
                     GAQAFSSFDTYLAPFVKADHLTYPEVKKCIESFIYGVNIPSRWGTQAPFSNITLDWTVP
                     EDLKNIPAIVGGKDQDFTYGECKAEMDMINKAFIETMIEGDAEGRGFQYPIPTYSITSD
                     FDWSDTENNRLLFEMTAKYGTPYFSNYINSDMKPSDVRSMCCRLRLDLRELRKKSGGFF
                     GSGESTGSVGVVTINMPRIAYLSENEEEFYKRLDRMMDISARSLHIKRTVISKLLDEGL
                     YPYTKRYLGSFDNHFSTIGLIGMNEAGLNAKWIRKDMTHEETQEFTKNVLNHMRERLSD
                     YQEMYGDLYNLEATPAESTTYRLAKHDVAQFKDIITAAECNGTPYYTNSSHLPVGYTED
                     VFAALDIQDELQTLYTSGTVFHTFLGEKLPDWKAAAALVRKIAQNYKLPYYTMSPTYSI
                     CQNHGYLSGEQYKCPICGKETEVYSRITGYYRPVKNWNDGKTQEFKERKVYDITNSHMK
                     IKTKAAAEYERSIQTAGEKAADIEEGEKETKTFLFTTKTCPNCKIAVNSLKKAQIPYEI
                     VDAEENMELAQKYGVMQAPTLVIVQEQEIKKLANASNIKAYAEKEQKEK"
     CDS             17417..18325
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_423"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.7e-47, bitscore:
                     155.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDIGIIGGGTAGMTAAIYGQRAGKRTVIIEGTNFGGQITSSTNV
                     ENYPGIASVSGSEFSMNLLDQAMKLGAETVVDQVSTVTKEEGMFVLETSEKAYPCRSVI
                     LATGVTHRHLGIEKEEKLVGAGVSYCATCDGAFFRDRDVAVIGGGNTALQDAEFLSNYC
                     RKVYLVHRRDEFRGEKSLVKRLEEKENVEFVLSATVKDILGESMVEGLILHNKKTEEDF
                     QIEVSGVFVAIGHIPQNDRFKELVELDEGGFIEAKEDCLTSCPGVFAAGDCRTKEVRQL
                     TTAAADGAVAGLAACKYLAGE"
     CDS             18540..18983
                     /locus_tag="ctg3_424"
                     /transl_table=11
                     /translation="MKETFRVIARKTTAGLQVESEARGFKLIMDEPEGLGGTNTGMNPV
                     EALLCALGSCQSIVAFAFAEANGIHLEGFHVELEGDLDPDGFMGLAEGVRNGYQEIRYS
                     MHFKSNASEEELEKYAAFIESRCPVGDCLQNGVPMKLTKVVVE"
     CDS             19038..20681
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_425"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.3e-63, bitscore:
                     208.3, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6.3e-15, bitscore:
                     50.2, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 5.6e-32, bitscore:
                     105.7, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEVKVPIIPGKKPGIVGKIDINVGEKVKKDQILCSIETAKGNRQ
                     IKASADGYIKEILVEEGQEVTANEVLILLDEILQVKVEADVKTMEKDLLVIGAGPGGYV
                     AAIYACKRGLDVVLAEKSKLGGTCLNMGCIPTKSLVQSAHCYNALKEMDLFGIEGDFHA
                     SVNIEKVLQRKNSVVDTLVSGIEYLIDKNKIDCIEGKAEFINDKLVKVGDKRIQAKNII
                     IATGSVPDTLKVEGYDLDGVIDSTEALRLNKIPDTLLVIGGGVIGSEFAFIYNTFGSKV
                     HIVEFQDRLLPMLDPDAGREMERVCKEKNIHVSTSSKVVSIKETVEKKYVVSFEKNGKL
                     YSSIAEKVLMSTGRKANIDGLGLGNTSVKFNPQNGSIIVNEYKQTNVSNIYAIGDVSSG
                     LKLAHLASHEAMAAVDHMLGEKREVKEIHVPSVVYTDPEIAVIGYSEQDLKNQNRKYKS
                     CRFPFTANGKALTMNQNKGVIKLLTSEKGEILGAVICGPDASSLIASITIAMKNNVSVT
                     QLTHTVFAHPTTAEVIHEACLALIDRGVHM"
     CDS             20681..21601
                     /locus_tag="ctg3_426"
                     /transl_table=11
                     /translation="MDAKIVVLNSTDPYTNISREYSYYNHLSEDEVIFLLWQNKPCVVM
                     GRNQNIYKELDLEYIKEQNILPVRRFTGGGCVYHDLGNLNFTFISDQKNKNVDKWMRII
                     LNALKKEGVEAELKGRNDLLSNGKKFSGMAWLEDEEKFLIHGTLMIDLDLSMLLKCLTP
                     DMSKFVGKGIKSVQSRVVNLKELVSSISVESLKNSLLISFKNIYTNARFIKHVVHSDEI
                     HTCKMLKSHEWLFGKKEKAQIQRVFIIKGKPLTLDIYINNDIINNVDVFSDTLDLKKVE
                     KLKVNLLGKIYKDLYIENIIKSIWI"
     CDS             21617..22054
                     /locus_tag="ctg3_427"
                     /transl_table=11
                     /translation="LFDLDCCVAFVTNVASKTLSDSLNNRLIRHGVTKSQWIAMYYINR
                     EGNLTQKLLADLMGAKEPTITGILDRLEREGLILRQGDVNDKRKKILVLTDKGRLINAK
                     LTDIAQEFRDVCLAGISEKDQKTFLEILDKMVAAATNWNKK"
     CDS             complement(22347..22847)
                     /locus_tag="ctg3_428"
                     /transl_table=11
                     /translation="MNDAMYEQIVARKPRPYDLLVRILIVLLIVAIIFFGMPLIGMLAL
                     LPALVVGFLAYYIIFPRLNVEYEYSILNHDIQIDAIYSKAKRKAKLGFDIQQAEIIAPA
                     KSPRLQSYHAEKTYDFTSGEAAAKVYAIMISLEQKNSCVLIEPDDKMLDHMKQWMGMKL
                     YQD"
     CDS             complement(22850..23761)
                     /locus_tag="ctg3_429"
                     /transl_table=11
                     /translation="MEQTPALKKALGELKRITGISLDMHPASNEEMEAAVRQIHCLTTA
                     YKEKYNKTDFLYSLLSGNIQTCELKERASRLHIQSEQLRILFLLETKTAYDDTVLEILK
                     NIFPAQAKTYLIPVNAQRIAVLKPAAPTEGSPDDCTKSARMIVDTLNTEALIHVQVSFS
                     SLLHSLADLPGAYEETSLALKVGKLFFSEQTVFPYNKLGIGRLIYQLPVPLCENFLKEL
                     FGEELPHTFEEDTVVTINKFFQNNLNIAETSRQLHMHRNTLIYRLEQVEKRTGLDIRRF
                     EDAMTFKIAMMVMNYLQTERNL"
ORIGIN
        1 tccacatata ggatgatagg ggaggatatg gagtcagtct ctatccagca aaatgcctgg
       61 aacgacgtat attatggcat ggcggatgat ctgtgtgaag gaaattattt tctctataat
      121 gaatattccc aggaaaccga caaggcagat attctttctg attatatgga aagcaacttt
      181 ctattactac gtaaatatat ggactgcggg ttgttcgacc gggcgggaga gtcgctgctt
      241 gagaacttgt cagcagatgt atcggagaat ttgcaggaag aagatacagg gtacgcgttc
      301 cgtgcggaat ttaccttcca ggaagatggg gacttgtctg atatcagtgt gaccggaaca
      361 aagatagacg aggaaacaca gtactatgcc cagaaaagtt acctaaagga aatggaaaat
      421 acagaaatat cctattggag cgatatatct acgccgcaag gggtgaccgt tatctatggt
      481 atgacagaag aaaatctgaa tgcctatgcg gattcggtca gcacgacgag atttccgtcg
      541 gcatacaatg tgatcgccta cagcaggatg ctgacatttg ccatgttgtt tgcggcattt
      601 gcggcagcgg cggcactgct tttgcctttc cgacacaaat tcgatatagg aaatgcggcg
      661 atatttacgg ctcctttgga agtagtactg tgcgtactgt ggtttttgta tataagtctt
      721 tatccggcgg catcggtcgt actggcaacg atcaaccagg aactgccgca gattgttcag
      781 gggcagaaca gtctgttaaa cgaccagttt gccatatgta ttaacttcct catgtggttt
      841 ttgatttacc tggcggtata ttgggtattt acttgtctaa gggcgatttt tacgatgaag
      901 agagaatatt ttataaaacg gacgctgacg gcgaaggtga taggctggct caaagacgga
      961 ggtggaagca taggaaagaa aatcggaagc gggatcaaaa atatttggaa acgtatccgt
     1021 acatttgcgg caaagcagta cgattcactg ctgcatttga attttcagga taagacaaac
     1081 cgtacgatct tcaagatcat cgggattaat tttatcgtct tggcgatcat atgcagtatg
     1141 tggtttttcg gtttgtttgc gctgtgtatc tattcggttt tactgttttt cttcctgaag
     1201 aaatatttcc acgatctgca ggacaaatat aaagtattgt tacagtctac aaaccaactt
     1261 gcaaatggag atctagacac gccgttggag ggagatctgg ggatatttgc cccgatccag
     1321 gaagaactca aaaagatcca gaagggcttt aagaaggcgg tggagaagga agtaaaaagc
     1381 gaaaggatga aaacagaact gatcaccaat gtttcacatg acctaaagac tccgttgaca
     1441 gcgatcatca catatacaga tctgctgaaa acagagcggg atgaagccaa aagaaaggaa
     1501 tatattgatg tattagaaag aaaatctctt cgtctgaaag tcctgatcga agatctgttt
     1561 gaaatcagca aggcggcgag taaaaatgtg atcatgcatt atatgaaagt agacattgta
     1621 gatctgttga aacaggtagg tctggaaaac gataataaga tcaaagaggc aaatctggaa
     1681 tttcgttgga agcttccgga gcataaagtg atactgaacc tggacagtca gaaaacctac
     1741 cgggtatttg aaaatctgat cgtcaacatc acgaaatacg caatgcccca tacgagagca
     1801 tacattgaaa tggaagaaag tgattcacag gtgcgtattt ttatgaaaaa tgtttccgcg
     1861 acagaactga atttcaatgt agaagagatt acagacagat ttgtaagggg agattcttca
     1921 cgaaatacag aaggctccgg actagggctt gcgatcgcaa agagcttcac acagctgcag
     1981 cacggagagc tgaagatcga gacagaggcg gatcttttta aggcggagat tatattcccg
     2041 aaaaatatag agatcacaga tacggaagaa tctgacacat catctggtgg tgagaacagc
     2101 gtttcataaa gatacttgcc tttttataca ggtcgtggta tagtttcttc agaatcaatg
     2161 aaagaggtgg aaggatgatt aacttttctt gcagataaga tcggaatata caataaggct
     2221 gcttttgcag gattattgtg tctgttgcaa gaaagtgatc aatcgttctc tcatggcata
     2281 gtttccttca tttattgaag aattgttttg cgtataatga gctgtaagag ttactttctt
     2341 gcggctcttt ttgtatttca taggaaatta cttaattatg aaagaagaga agattgcagg
     2401 gatcgcactg cggcggaaag gtatcgtgtt gctgaagcag cctgccacag gcggagaatg
     2461 ctgcgatgtg gaactttttc tgaatgaagg acattttctg cttatagacg aatcaacaaa
     2521 ccatttagat tcggatgccc gtaaaaaagt atccgcatat cttagaaaga aaaaaggatt
     2581 tattttagta tcccatgacc ggcggttttt agatggatgt gtggatcata ttttgtcctt
     2641 aaatagagca gacataaaag tacaaagtgg aaacttttca tcctggatgg aaaattttgc
     2701 atggcagcag aaggcggaga tttcgcaaaa tgagcggtta aagaaagaca tacgcaggct
     2761 gcagaaagcg gcgaagcgtt ccgcggtatg gtctgaacgg atagaggctt ctaagatcgg
     2821 cgcggcagat aaaggatatg tcggacataa agccgcaaaa atgatgaaaa ggtctaagac
     2881 catggaaaaa cgtcagcagc agagtatgga gcaaaaagcg gcattgctta aaaatgcgga
     2941 aaccatagat acattaaagc tctatccgat agagtatcat acaaatctgc ttgccgcatt
     3001 ttcagatgta gcggtgctgt atgacggacg gcagatctgc cggtctgtat cgttccaagt
     3061 gcgggaggga gagcgtattt ttattgaggg aaagaatgga agcggaaaaa gcagtctgct
     3121 aaaattgctg tctggtcatc cgatcgaaca tacaggcaca ttgacgatag gatccgggct
     3181 tgtgatttct tatgtgcccc aggatacgtc gcacttgatg gggacattgg cggtattttc
     3241 ggaagagaac ggtctggatg agagtctgtt taaggcggtt ctcagaaaga tggattttga
     3301 gcgtgtacag tttgaaaaag atatgaaaga tttttcagaa gggcagaaga aaaaagtcct
     3361 gctggcaaaa agtctttgcg agaaggcaca tttatatgtg tgggacgaac cgctgaattt
     3421 tattgacgtc tactctcaca ggcagatcga acagctgata gaaagttttt ctcctactat
     3481 gcttttggta gaacacgata ttgcttttcg agaagcgaca gcgacaaaaa cgatcaaatt
     3541 atagatatac atagagcagg aaagaacgtt tagacactac aaagacagtt gtggtataat
     3601 cagaaaaagg ataaagaaaa aggaaaagag ggaatatgat tgagtgagga caaggaaaag
     3661 gaatacagaa cgctgcgtcc ctggcagggc tttcttgtga tcgtcatcgc ggcagtgtat
     3721 ctgtttttga ttgcgcctaa gttcataggg cggtttggaa gaatagggag tcttttagga
     3781 gaggcaggtt ttttgctttt gtctgtgact gctgtctgga tatggaaagg ggattttaaa
     3841 gtagtatttc cgttcaggaa accgtgtttt actacaatgg caggagtcgg gatattatgg
     3901 atgggaatga tgcttttgat ctccgttgcg acgatgctct tacagttgtt ttttccggag
     3961 gtatattttg aaacagggat tgagacagcg ctcggatata cgggtattcc ggtacttttg
     4021 ctgacagcga tcctggcggt atctccggcg atttgtgagg aagcgctgtt ccggggggtg
     4081 tttgtcaaca gtttgttgcc attgaaaaag aaatggctga tcattttgat cagcagtgtt
     4141 atattcggat tgtttcacgg cagtccggcg aaatttgttc cgactgcgct gggcggtgcc
     4201 gcattagggt ttgttttttt ggagacagga aatctgtttt atagctgtct ataccatttt
     4261 atcaataata tgtcttccgt gatcgtgctt gcggccatgg gagatatata caaatatatg
     4321 gcgcggacag gggctttttc tgaaatgcag cagattccgc tgacaagtat aggattatct
     4381 gtgatgatgt ctgcggcggc tccggcatgt ctgtatatcg gcaactatct gctgcacagc
     4441 cagacggaag gataccgaga gacactgttt cccagaagga aaccaggtat cgtgatctcc
     4501 ctgatcgcgg tttccggtat tctctttgta tcaggagtgt atcttttcct atatggaatg
     4561 atagaaatag gactgcctgc tttttaaagc ggacagtcct atttctattg aaaagagacg
     4621 ttttaaaaaa gatatgcctt taatgtgtaa aaaattctat agagagaata tacttgtact
     4681 gcgttttaag atccctttca tgtgcgcgat ggcagtgccg taattggtga tcggaatacc
     4741 ctgatccttt gcgcagcgaa ggcggtattt catttctcgg tcattgagca tgcagcctcc
     4801 gcagtggatg acgagctgat aaggggacag atcatccggg aattgcgttc cgcttgtaaa
     4861 ggcaaaacgg agctgtctgc ctgtatgttt ttggatccag ttaggcagtt tgacagtgcc
     4921 tatatcatta cattgccggt ggtgcgtgca cccctcagag atgagaaccg tgtcattttc
     4981 ttttaattca tccaaaacag cggcgccttc agtcaaaatt ttcaaatccc ctttatatct
     5041 ggcaaatagg atagagaaag aagtaagggg gatatcgggc ggagtaacgg cggcagcttg
     5101 ttcaaatacc tgactgtcgg taatgacaag agcaggctgt ctgtccaagc gccgcagggt
     5161 atcttctaac tctgtgtccc tgacagtaac ggcaacagcg ccggaatcta aaatatctcg
     5221 gatcgtctgc tgctgcggca gaatcagacg tccttttggc gctgcggagt caatggggac
     5281 tacaagaacg acaaaatcgc cgggagagag cagatcgcct acgatttttt tgtcgatatt
     5341 ttctgtcgca gcacagcggg cgatcagttc ttttaactgg tgtatgttct ttccggttgc
     5401 ggcgctgacg tgtatgacat tttcttctgc cgcaggggag agaggcgtcc tatcgcattt
     5461 attgtaggca atgacatagg ggatttcttt ttcctgtatt ttgcgtagaa tctcccgatc
     5521 tttttctgtt agtcccacac cggcgtctac tacgagaacg gcaatatctg tcttatttaa
     5581 catctggaag gcttttttga cacggagcgc ccccaatgct ccttcatcat ccagtcccgg
     5641 agtatcgatc aggacgacgg ggcccagagg cagaagctcc atagctttta agacaggatc
     5701 ggtagtggtt ccttgtatat cggatacgat tgccagatct tgtccggtga gcgcattgat
     5761 gatgctggat tttccagcgt ttctcctgcc gaaaataccg atatgaaggc ggttagcaga
     5821 cggtgtggca tttaagttgc tcataggatc ctcctttttg cagtatgtat ttgtgctgcg
     5881 tatatctgcg tgaaagactt gttgtgtcag aagcggaaat ctcggcgatt gtcctgttcg
     5941 atcagccgca gattttccag caccacagag cgtgctttct cattggggac attgaagact
     6001 tccttttcaa tgagcgcgtc gccgattgcc tttgtttttg gagaagcgta gtccatgaga
     6061 tattctttca gcgtcatcag tgcgttcggg tggcagcagt tctggatctg tccgctttta
     6121 cacagggaca tgaaacgatc tccggttctt ccttcacggt agcacgcagt gcaaaagctg
     6181 ggaatatagc ccatctccat cagccaacag acgacttcat cgagtgttct tgtatcgacc
     6241 acgtcaaact gttctgactt ttctgtatcc ggttccggct cacagtagcc gcctacactg
     6301 gtacgggagc cgccgctgat ctgagaaata cccaggtgca gcacccgttc tcttgttttc
     6361 tggctttctc ttgtggagat gatcatgcct gtataaggaa cggcgatacg gatacaggca
     6421 actaatttgg caaaagtatc gtcatcaata ccgtttttaa atgaggagga gtcgatatca
     6481 tccgcgtcac gcaggcgggg aacactgatc gtatgtggtc ctacaccgaa agcagcctct
     6541 aaatgttctg catgcatcag aagtccggcg aattcgtagc ggtatttatc cagaccaaat
     6601 aaaacgccga ttccgacatc gtcgataccg ccttccatag ctcggtccat tgcctcggtg
     6661 tgatacgcgt agtcatgctt tggacctgtc ggatgtaatt ttagatagct ttctttgtga
     6721 taggtttcct ggaataagat gtatgttccg atccctgctt cttttaataa acgatagtta
     6781 tctacagtcg tcgcagcaat attgatattg acccgccgga tcgcgccgtt tttgtgctta
     6841 atgctgtaga tggtattgat agagtccaga taataatcca ttgtattgcg tatcgggtcc
     6901 tctccggctt ccagggcaag acgtttatgg cccatatcct gcagtgcgat gacttctcgg
     6961 cgtatctctt cctgtgtcag ctgctttctg gcgatatgct tattttttgc gtgataagga
     7021 cagtaggtac agccgttgat acagtaatta gacagataga gcggagcgaa cataacgatg
     7081 cggtttccat agaaatcttt cttgatctgt tctgccagac gaaagatttc ttcatttttt
     7141 tcttttaagt cacaggcaag cagtacagaa gcttctctgt gggagagtcc ttttcgtttc
     7201 ttcgcctttt cgatcagagt gtcgatcaaa gcggcattat gtttgttttc gtcggcatag
     7261 gcaagtgttt ctaagatttc ctcgtgattg ataaagtctt cggcatgttt tgaatgtaca
     7321 tcatacatag ttgcatcctc cttcattttt attaagcaat ggttttaaat atttaaagaa
     7381 tctccgcggg caacgacggt gcggcaaccg atgctgttca tgcggcgttc caggcattgt
     7441 ctgcattctg ccgcttcatc cccggtacag atcttattat cgtagagcag ataatctttg
     7501 cgcacatcct gcggggaaag attgggcatt accacgtttg ctccggcgag gatcccctgt
     7561 tctcgtccgt ccggcgctat ggtgccaagt gctgttgtag caggcagcaa gactttggga
     7621 agcatgaccc ggatgagtgc gagcataaag agcgttaagg aaagcgtacc cgcctgttct
     7681 ctggcaaaag gcgtctcctg gtgcggaatg aaaggtccta tccctaccat atgtggatcc
     7741 agccttttta aaaagagcat gtcatctgcc agattttcgg gtgtttggaa aggagaacct
     7801 accataaaac ctgttcccac ctggtagccg atctctttta gatcccacag gcacttttgg
     7861 cggttcgcag cgcttaaagc ggcagggtgc agcctggcat agtgggaagc gtcaaaggtt
     7921 tcgtggcgca gcagataacg ggaggcaccg gcgtcaaata aacgctgata gctttcaagg
     7981 gagcgttctc caatggatag agtaatggca caatcgggat aggagctatg gatcgtactt
     8041 acgatatctt ccattacttc gtcggtataa tagccatcct ctccgccttg gagcacaaaa
     8101 gtacgaaaac caagcgcata acctgtgcgg cagcaggaaa ggatttcttc ttttttgagc
     8161 cggtagcgtc gagcgttttt attacttctg cgaatgccgc agtagagaca gtcgttttta
     8221 caataattgg taaactcgat cagcccgcgt atatagatgt cgtgtccgta atatttttca
     8281 cgaaattttc gtgccagtaa aaacagatat tcgctgtttt ctttcgttct gccccgaata
     8341 agctgtaccc attcgtcttt ggagagagta tgggcacggg caagcttgtc gatcaaaatt
     8401 ttcatattgt ccatagtaac tcctgctgtt tgttattttg gttttgcata gattgtcttt
     8461 gtgctgattc cgggaagcat gcccagcttt ccggacaggg cgctgatgac gtcgctggga
     8521 gcgtcaagcg tgatactaat gatagaaatt cccttttccc ggtaaggaat tcccattctg
     8581 ccgataatgt aggcagagta ttgactcaat agatgattta gatcgtctat ggcttcattg
     8641 gaattgacta caataccgat caaagcaatc ctggtatcca tggaaaacct cctctcatag
     8701 atggaatcag agaaaaaaat acctgtgccc agaaagcaca ggtatgacaa aaacagggga
     8761 ctcccctgtc agcttttcct atatgtgcct tcttacttag gaaatccctt tgtaatcaga
     8821 acaaaagtat gagtatagta tagcataggg aagaaaaata tacaatcata gagttgtttt
     8881 gcatagatat attctatgta ttcaaaaaga gaggcgacat ggtgttaaaa aatataagac
     8941 agagctgacg cagcggagat ttttctgcgg caccgattct ttttcctatt gtaacttacg
     9001 cagttgtatg gtattattag actaaagtac aaacaatagt ctaaaatgaa aaatcaacag
     9061 atgagaaagg aaaaaagaaa tgagcttgat cacagatata cagaagtatt ccatccatga
     9121 tggggatggg atccgtacga ctgtattttt taaaggctgt gctctgcgct gtcaatggtg
     9181 tcacaatccg gagacgcaaa ataccggacg ggagctgctc tgccacacgg aatcttgtgt
     9241 tggatgcgga gcatgcgtag aaatctgccc tgcgcatgcc gtgtgcatac aggaaggcaa
     9301 ggcatggaca gacagagaga tctgtacagc gtgtggaaga tgtacggaag tttgtaatct
     9361 gaatctgcgg gagattgcgg gaaaagaata tacagtggat gaccttgtaa aagagctgaa
     9421 aaaggacgaa atgttttacg aagagtctgg cggcggggtg acactgtccg gcggcgaggt
     9481 gatgcttgcg gacatggatt ttgtggaggc agtggcaaag aggctgaaag ccgccgggat
     9541 ccatgtggcg atagatacgt gcggctatgc gcctcgcgca aattttgaaa gacttctgcc
     9601 ctttgtggat ttatttcttt atgatataaa gaccatggat acagccgtac ataagaagta
     9661 catggggttt ggaaatgaac agatactgga aaatctggaa tatctcaatc atgcgggcgc
     9721 agatatatat atacggatac cgacgatcaa aggagttaat gcggatgaaa agagtatgag
     9781 ggcgatcctt tcctatctga aagaaaaaca gatccgggtc ttgcagatca atctgcttgc
     9841 gtatcacaat acgggaagcg caaaatatgc aaggctgggc agagcgtatg agggagacgc
     9901 actttgtgcc ccatcggggg aagaaatgca gacatttgca gatttatttc aggaagcagg
     9961 atataaagta aaaataggtg gataaaagga gatgggtaag atggaagaaa gaggaatgaa
    10021 tgaaagaatc aaaaaattga gaaaagtcag cctggataca gaggcacata ttgacctgga
    10081 acgggcaaaa agcgagacaa ggacatatca aaaatatgaa ggggaaatat cggtgccaga
    10141 actgcgggcg caggtgctca aagagtattt tgcgacaaag acactctata tcggagaggg
    10201 agagctgatc gtgggagaga aaggggattc tccccaggct gcgcctactt ttcccgaatt
    10261 gtgctgtcat actgtagatg atatgcgtgt gatgaatgac cgggaactga tcagttttaa
    10321 agtgagagaa gaagattatc aagtacagga agaagtgatg attccctact gggaaaaacg
    10381 ttcgatccgt cataaaatac tgcggcagat gacgccggaa tggaaggcgg catatgaaag
    10441 cggtattttt acagaattta tggagcagcg gggaccggga catacagtgg gttctgtgaa
    10501 aatctatgag aaggggtttt tagattataa aaaagagatc gaggaagcga tcgatagact
    10561 ggacttttta aatgacaaag aggcatatga taaaaaaaat gaactagaag gaatgaagat
    10621 cgcgtgtgac gcgatcatgg ttctgggaga acgatatgcg gcatatgcaa gggaattggc
    10681 gcagacagaa agagacgaga caagaaaggc agaactgctt cagatcgctg ccaactgtga
    10741 tgtcgttccg gcacacagac cgcagacgta ctggcaggcg atccagatgt actggtttgt
    10801 acacttaagc gtgacaagcg aattaaatcc atgggatgcg tacagtccgg gacgctttga
    10861 ccagcactta aatccatttt accaaagaga tatagaggca gggatcttag acgagaaacg
    10921 tgccctagag ttattagagt gcctgtgggt aaaattcaac aatcagccgg ctcctccaaa
    10981 agtgggcatc acgctgaaag agagcgggac gtatacagat tttgccaata tgaatacagg
    11041 cggcatcacg ccggatgggg aaaatggtgt taacgacgtc agttacctga tcttagactg
    11101 catggatgaa atgaaactgc tgcagccaag ttcaaatgtg cagatcagta aaaagacgcc
    11161 gcagaaattc ttaaaacgcg cctgcgaaat ttctagaaaa ggctggggac agcctgcctt
    11221 ttataatacc gaggcgatca tacaggaact gctcaatgct ggaaaatcgc tggaagacgc
    11281 aagacgaggc ggaacaagcg gatgtgtgga gacgggggct ttcggaaatg aagcatatat
    11341 cctgacaggc tattttaatc tgcctaagat ctttgaattg acactgcata acggatatga
    11401 taaagtggca ggaaaacagt taggacccaa aacaggcgat gtgacagaat ttacgacata
    11461 tgaggaagta tttgaggcat ataaaaaaca gattgcctat ttcctggata ttaagatcaa
    11521 gggaagtaat gtgattgaaa agatttatgc agagcatatg cctgttccgt ttttatctgt
    11581 gatcaccaat gattgtatca gcaaaggaaa agattacaat agcggaggcg ccagatataa
    11641 tacaaaatat atacagggcg tggggatcgg aaccatcacg gactgtctgg cagcagtcaa
    11701 atataatgta tttgatgaaa agaaatttac aatggcagag ctgttagaag cgttggaaga
    11761 taattttgaa ggacatgaga ggattttaaa cctggtaagg aataaaacgc cgaagtatgg
    11821 caatgacgac gattatgctg acgacattat gaaggcggta tttgcgtact accgggaaca
    11881 ggtgactggc agaccgaata tgctgggagg gacatatcgt atcaatatgc tgccgactac
    11941 ctgtcatgta tattttgggg aagttatgat ggcgagcgcc aatggccgcc tggcacataa
    12001 gcctgtttca gaagggattt ccccggaaaa aggagcggac ataaacggac cgacggcagt
    12061 cgtaaaatcg tgctctaaga tggatcatct ccagacggga ggcacgcttt tgaaccagaa
    12121 gtttacaccg agtgtggtgg cgggcgagga aggccttgat cagatggcga acctagtccg
    12181 tacgtatttc aatatggacg gacatcatat ccagtttaat gtgatcgata aggagacgct
    12241 gatagaggca cagaagcatc cggacgacta taaagattta atcgtcagag ttgcaggata
    12301 cagcgatcat ttccggaatc taagcaaggc tttgcaggat gagattattg agcggacgga
    12361 acagagcttt cactaaatga tagaagaact tccggcaggg tagtgacttt ttttgaaatt
    12421 cgtaatagaa tgataagaaa aggacggtgg gaccatgtcg gaagtaagac agcatattgt
    12481 attccacggc agagtacagg gagtgggctt tcgctatact gcgaaatatc ttgcccagtc
    12541 tttggagctg accggctggg tgaaaaatga atgggacggc actgtgacaa tggagatcca
    12601 gggccgggaa gctttgatac ataaattatt aaaaggttta aataacggac attttatttc
    12661 gattgaatgg atggatacta tagaacttcc gttggaggaa gaaaggggtt tctacgtaaa
    12721 ataaaggctg aaggaggaaa aaataagatg aaactgggct ttatcggaac aggaaatatg
    12781 gcaggtgcta ttatgggagg cattatcaaa aaagggattt ttaaaccgga agagataatg
    12841 ggctcagata taagcgaaca aggaagaaaa cgtgtgcagg atatgtatgg catctgcgtg
    12901 acgggagata accgggaggt agcttcaaaa gcagaagtac tgcttctctc tgtaaaaccg
    12961 cagttttatg cagagacgat agcggaaata aaagatgttg ttgcaaaaga gcagatcgtg
    13021 atcacgatcg caccggggaa gacgctggac tggctgcggg agcagtttgg aaaagaggta
    13081 aagatcgttc gtacaatgcc aaatacgcct gccatggtgg gcgaaggaat gacggctgcc
    13141 tgcccgaatg aatttgtgac agaggaagaa aaagcgtatg tgcagaagat attagaggct
    13201 tttggaaagg tagagatcat tccggaaaga ctcatggatg cggtcgtttc tacgagcgga
    13261 agttctcctg cctatgtatt tatgctgatc gaggcaatgg cagacgcggc tgttgcggat
    13321 ggaatgccaa gaccacaggc gtataaattc gcggcgcagg cagtgtatgg cagtgcaaag
    13381 atggtgttgg agacgggaaa acacccggga gaattgaaag atatggtctg ctcgccggca
    13441 ggtactacga tagaggccgt gagggtattg gaagaaaagg gcttcagaag tgctgtaata
    13501 gaagcgatga agacatgcgc ggaagtttca aggaagatgt aacatggata aggaagagaa
    13561 aaagaaaagc gtaaagacta ggatcgtatc tgcggcatgg cagttgttct atgagaaagg
    13621 gtatgatcag acgacagtgg acgatatcat cgcactgtcg ggaacttcca aggggtcttt
    13681 ttattactat ttcagtacaa aagatgaact gcttggcaca ttgtccaatg tcttagatga
    13741 tttctatgag gaattggctg ccaggatgga accgtctatg aacagttttg ataagctgtt
    13801 atatctaaat gaaaaagcac atgagatgat tgagaaaaag atcccgcttg atcttttgac
    13861 ttctctgtat tctacgcagc ttacgtttaa aggcaaccgt catcttctgg ataaaaacag
    13921 agtatactat cagcttatca cagagattgc ggaggaaggg caaaagcggg gagagatacg
    13981 cacggacaag ccggtcagtg agatcgtgag atattattct ttgtgtgaga gggcgttgat
    14041 aacagattgg tgtttaaatc agggaagtta ttctctgcat gcttacacga aggaatatat
    14101 gcctgttatg ttggcgtatt tcagacaaaa atcggaggaa gcataatggt gatacaagga
    14161 ctacagaagt tgacgctttt agactatccc ggaaaggtgg cctgcacgct ctttacggca
    14221 ggctgtaatt tccgctgtcc gttttgccac aatgcttcgt tagtgacaca tgtagacaga
    14281 aaaaatgata tacctgaaga ggaggtactt gcctttttaa aaaagcggcg gggacttctg
    14341 gacggggtat gtataacagg aggagagccg ctgctccagc cggatataga agtatttata
    14401 agaaagatac gggatcttgg ctatctgatc aagttggata caaacggaag caacatattg
    14461 ttgcttaagc gtctggcaga agaaggatta ctggattatg tagcaatgga tattaaaaat
    14521 gcgcctgata aatatggagt gactatcgga atcgaggaat atgatctgga aaatatactg
    14581 caaagtgtag agtttctcct ctcgggttcc ataccgtatg aatttcgcac cactgttgta
    14641 agagaatttc ataaacgaga agattttgcg gcgattggaa gatggataag aggagcggaa
    14701 aaatattatc tgcaaagctt tcaagattcc ggggatctga tcgctccggg actgcgggga
    14761 tatacgaaag aaattatgga acaggcgctt gagatcgtca gaaaaaatgt accgaacgca
    14821 gaattgcgag gggttgaata aacaccaata tctagtgtat tgttttggca acaaaaacta
    14881 gatattggtg tttttgattg acatgatttt agaaggatga tacaatagat acagtgtctg
    14941 acgaaataca atatgtaaat attattaaaa agaaagggga cggaataaaa atatgtatca
    15001 ggtaacaaaa agggatggga agattgccga atttaatctg gtaaaaatca gcgaagcgat
    15061 acggaaggct tttgaggcgc aggagaaaca atataaccag gatatcatag atttgcttgc
    15121 actgaaagta acggcagact ttgagcccaa gatcaaagat gagctggtgt ctgtggagga
    15181 tatccaggac agtgtggaat ctgtgctgat caaagcgggt tacgcagatg tggcaaaagg
    15241 ctatattttg tatagaaagc agagagaaaa gatccgaaac ctaaattcta cccttttgga
    15301 ttataaagaa attgtggaca gttatgtgaa aatcacggat tggcgtgtaa aagaaaattc
    15361 tactgtgacc tattccgtag gcggacttat tttgagtaat tccggcgcga tcacggcaaa
    15421 ttactggctt tccgagattt atgatgagga gattggaaaa gcgcataaaa atgcagatat
    15481 acatatccat gacctttcta tgctgacagg atactgtgca ggctggtctt taaagcagct
    15541 gatacaagaa gggcttgggg ggattccggg aaggatcact tctgcgccgg caaagcactt
    15601 gagtgttctg tgcaaccaga tggtgaattt cttaggaatc atgcaaaatg agtgggcagg
    15661 agcacaggcg ttttcctctt ttgatacgta tcttgccccc tttgtgaagg cagatcatct
    15721 gacctatccg gaagtgaaaa aatgtattga atcgtttatt tatggtgtga atattccgtc
    15781 acgctgggga acacaggctc cattttccaa tattacgctg gactggacag taccggagga
    15841 cttaaaaaat atcccggcta tcgtaggcgg aaaagatcag gactttacat atggggaatg
    15901 taaagcggag atggatatga tcaataaggc ctttatcgag acaatgatcg aaggcgacgc
    15961 tgaaggaaga gggtttcagt atccgatccc tacgtattcg atcacaagtg actttgactg
    16021 gtctgataca gagaataatc ggctgttgtt tgaaatgaca gcaaaatatg ggacaccgta
    16081 tttttccaat tatatcaaca gtgatatgaa accaagcgat gtgcgcagta tgtgctgtcg
    16141 tctgcgtctg gatctacgtg agttacgtaa aaaatccggc ggcttctttg gcagcggtga
    16201 gagcacggga tcagtcgggg tcgtgacgat caatatgccg cgtatcgcat atttatcgga
    16261 aaatgaggaa gaattttata agagactgga ccgtatgatg gatatttccg caaggtctct
    16321 gcacatcaaa cggacggtta tatccaaact tttagatgaa ggattatatc cttatacaaa
    16381 gaggtatctg ggttcttttg acaaccattt ttctacgatc ggtctgatcg ggatgaacga
    16441 ggcaggctta aatgcaaaat ggatacgtaa ggatatgacc catgaggaga cacaggaatt
    16501 tacaaagaat gtgctcaatc atatgcgtga acgtctgtct gattatcagg aaatgtatgg
    16561 agatctatat aatctggaag cgactccggc agagtctacg acctacagac tggcaaaaca
    16621 tgatgtggcg cagtttaaag atattattac ggcagcggag tgtaatggaa caccttatta
    16681 tacgaacagc tctcatcttc cggtaggcta cacagaagat gtatttgcgg ctttggatat
    16741 tcaggatgaa ttgcagactt tatacacgtc cggtacggta tttcatacgt ttctgggaga
    16801 gaagcttccg gattggaagg cagcggcagc gctggtaaga aagatcgcac aaaattacaa
    16861 attgccgtat tacacgatgt cacctacgta ttcgatctgt cagaatcacg gatatctatc
    16921 gggagaacag tataaatgtc cgatctgtgg aaaagaaaca gaagtgtaca gccgtattac
    16981 aggatactat cgtccggtaa agaactggaa tgatggaaag acacaggaat ttaaagagcg
    17041 taaggtatat gatattacaa attctcacat gaagataaaa acaaaagcag cggcagaata
    17101 cgaaagaagc atacagacgg caggagagaa ggcagcagat atagaggaag gcgagaaaga
    17161 gacaaagacg tttcttttta ccaccaagac ttgtccaaac tgcaaaatag cggtaaattc
    17221 tttgaaaaaa gcacagatcc cttatgagat cgtggatgca gaggagaata tggaactggc
    17281 gcagaaatac ggagttatgc aggcgccgac attggtgatc gtacaggagc aggagataaa
    17341 gaaactggcg aatgcctcta atatcaaagc atatgcagaa aaagaacaga aagaaaaata
    17401 aaggaggcag cagagtatgt atgacattgg aatcataggc ggcggtacag ccgggatgac
    17461 agcggcaatc tatggacagc gtgctgggaa gcggacagtt attatagaag ggacaaattt
    17521 cggtggacag atcacttctt ctacaaacgt ggagaattat ccgggaatag ccagtgtaag
    17581 cggcagtgag ttttccatga atttgttaga tcaggcgatg aagttggggg cagagacagt
    17641 agtagatcaa gtaagtacag tgacaaaaga agaagggatg tttgtcctgg agacttccga
    17701 aaaggcgtat ccatgccgtt cggtgattct tgcgacagga gtcactcatc gtcatcttgg
    17761 gatagagaaa gaggaaaaac tggtgggcgc aggagtctcc tactgtgcaa cctgcgacgg
    17821 agcattcttt agggacagag atgtggcagt gataggaggc ggaaatactg ctcttcagga
    17881 cgcagagttt ttgtctaatt actgccggaa agtatatttg gtacacagaa gagatgaatt
    17941 tcgcggtgaa aagagtctgg tgaaacgtct agaagaaaag gaaaacgtag agtttgtttt
    18001 aagcgctaca gtaaaagaca ttttgggaga atctatggtg gaaggtctta tcctgcataa
    18061 taaaaagaca gaggaagatt ttcagataga agtgtccggc gtgtttgtcg cgatcgggca
    18121 tattccgcag aatgacagat ttaaagagtt agtggagtta gatgaagggg gctttattga
    18181 ggcgaaagag gattgtctga cttcctgtcc gggtgtattc gcggcagggg actgccggac
    18241 aaaagaagtg cggcagctta cgactgcggc agcggacggt gctgtagcgg gactggcggc
    18301 atgcaaatat ttggcgggag agtaagaact ggaaaatcgg attttttaaa acagaaatat
    18361 ataaggttct tctatgagga gtcatagaag aacctttttt gtataaaaaa cgaaaaattt
    18421 gcaaaaaggt tgacagtttt tagacaatac tatatgttag tggtaagaaa acatagtata
    18481 ctaagtatta gctagctaag aaaaatgcat tgggaagaag caaaagaaag gagaaaaaaa
    18541 tgaaagaaac ctttagggta attgcaagaa aaacaacagc aggtttacaa gtggaatctg
    18601 aagccagagg ctttaagcta atcatggatg aaccggaagg attgggcggc acaaatactg
    18661 gcatgaatcc ggttgaagct ttattatgtg cattaggatc ttgccaatca atagtagcat
    18721 ttgcatttgc agaagcgaat ggaatacatc ttgaaggctt tcacgtagaa cttgaaggag
    18781 atttggatcc tgatggtttt atggggcttg ctgaaggtgt aagaaacggt tatcaagaaa
    18841 ttcgttattc tatgcatttt aaatccaatg cgagtgaaga agaattagaa aaatatgctg
    18901 cgtttatcga gtccagatgc cccgttggag attgcttaca aaatggagta ccaatgaaat
    18961 taacaaaagt agttgtagaa tagatttact tagggctgtt tgataacagc cctctatttg
    19021 aagaggatat atatgctatg atagaagtaa aagtccctat aatcccaggt aaaaagcctg
    19081 gtattgtagg taagatcgat attaatgtag gcgaaaaagt taaaaaagat caaattttgt
    19141 gctcaataga aacagcaaaa ggcaatcggc agataaaagc cagtgcagac ggctacatta
    19201 aagagatact tgtagaagaa ggtcaagaag taacagcaaa tgaagtgttg atattgctgg
    19261 atgaaatttt acaagtaaaa gttgaagctg atgttaagac catggaaaag gatttgttgg
    19321 ttataggcgc cggacccgga ggatatgttg cagccattta tgcctgcaaa agaggcttgg
    19381 atgtagtatt ggccgaaaaa tctaaacttg gaggaacctg tttaaacatg ggatgtatcc
    19441 caacgaagtc tcttgtccaa tcggctcatt gttataatgc attaaaagaa atggatttat
    19501 ttggtataga aggagatttt catgcgtctg ttaatatcga aaaagtttta cagaggaaaa
    19561 attctgtagt agatacattg gtttcaggca tagagtatct aattgataaa aataagatag
    19621 actgcattga gggaaaagct gaatttataa atgacaaatt agtaaaagtt ggcgataaaa
    19681 gaatacaggc aaaaaatatt atcattgcta caggatctgt gccggataca ttaaaagtag
    19741 aaggatatga tctggatggt gtgatcgatt cgacagaagc cttacgttta aacaaaatac
    19801 cagacacact tttggtgatc gggggagggg tgatcggatc agaatttgca tttatatata
    19861 atacatttgg ctcaaaagta catattgtag agtttcaaga ccgccttttg ccaatgttgg
    19921 atccggatgc cggtagagaa atggaaagag tatgtaaaga aaaaaatatt catgtaagca
    19981 cttcaagtaa agtagtaagt attaaggaaa ctgtagaaaa aaagtatgta gttagttttg
    20041 aaaaaaatgg aaaactgtat tcatcgattg ctgagaaggt cttgatgtct acgggcagaa
    20101 aagcgaatat tgatggactt ggcctcggaa atacatctgt taagtttaat cctcaaaatg
    20161 gcagtatcat agtcaatgaa tataaacaga caaatgtatc aaatatatat gcgattggcg
    20221 acgtgtcctc cgggttaaaa ttagcccatt tagcatcgca tgaagctatg gcggctgttg
    20281 atcatatgct gggagaaaaa agagaagtaa aagagataca tgtaccatcc gttgtataca
    20341 cggatccgga aatagcggtt ataggttata gtgagcaaga tttaaaaaat cagaacagga
    20401 aatataaatc ttgtcgattt ccatttactg caaatggtaa agcattgact atgaatcaaa
    20461 acaagggagt tataaaactt ctgacatcag aaaaagggga aatattggga gctgtaattt
    20521 gtggaccgga tgcgtcctcc ttaattgcca gtattacaat agctatgaaa aacaatgtgt
    20581 cagttaccca actgacacat actgtatttg ctcatccgac aactgcggaa gtaatccatg
    20641 aagcatgtct tgctctaatt gacagaggag tgcatatgta atggatgcaa aaattgttgt
    20701 tttgaattcc acggatcctt ataccaatat ctcacgggaa tatagttatt ataatcattt
    20761 gtcagaggat gaagttattt ttttattgtg gcaaaacaaa ccttgcgtcg taatgggaag
    20821 aaatcaaaat atatataaag agctggattt agaatatatt aaggagcaaa acattcttcc
    20881 ggtaagaaga tttactggcg gaggttgtgt atatcatgat ttaggtaatc ttaactttac
    20941 ttttatatct gatcagaaaa ataaaaatgt agataaatgg atgcgtatca ttttaaatgc
    21001 gttaaaaaaa gaaggggttg aagcagaatt aaaaggtaga aatgacttat tgtcaaatgg
    21061 aaaaaaattt tcaggaatgg cctggctcga ggatgaagaa aaatttttaa ttcatggtac
    21121 tttaatgata gatcttgatt tatccatgct tttaaaatgc ttaacacctg atatgagtaa
    21181 atttgttggc aaggggataa aatctgtaca aagccgggtc gtaaatttaa aagaattggt
    21241 ttcttctatt tctgtcgaaa gtttaaaaaa cagtctgctt atatcgttta aaaacatata
    21301 tacaaacgca agattcatca aacatgtcgt acattcggat gagatacata catgtaaaat
    21361 gttaaaaagt catgaatggc tatttggcaa aaaagaaaaa gcacaaatac agcgtgtttt
    21421 tataataaaa ggaaaaccct taacccttga tatttatata aataatgata taattaataa
    21481 tgttgatgtt tttagcgata cgttggactt gaaaaaagtt gaaaagttaa aagtcaattt
    21541 actgggaaaa atctataagg atttatatat tgaaaatatc attaaatcaa tatggatata
    21601 gaatggggaa atcttcttgt ttgatttgga ttgctgtgta gcgtttgtga caaatgttgc
    21661 atctaaaact ttatcagatt cattaaataa cagacttata aggcatggtg ttacaaaatc
    21721 acaatggatt gccatgtatt atataaatcg agaaggtaat cttactcaga agctgttagc
    21781 tgatctaatg ggtgcaaaag agccgactat tacgggcata cttgatcgac tagaaagaga
    21841 aggattaata ttaagacaag gggatgtcaa tgataaaaga aagaaaatac ttgtattaac
    21901 tgataaaggt cgcttgataa acgctaaatt aacagatata gcacaagagt tcagagatgt
    21961 ttgtttggca ggtatttctg aaaaagatca aaaaacattt ttagaaattc ttgataaaat
    22021 ggtggcagct gctacaaatt ggaataaaaa atagaaagga atctaaaaat tacggtatag
    22081 tcgttcgtgg ctataccgtt tttttggaac acctatgttt caagcttaat gaatagtgtt
    22141 ttgagcaact tttttggaaa tacttcatat aaaagctgta aaaaattacg ttgaattaat
    22201 aaaaattttt gattgataac atcattttgt acagtttatg gacgttgtac agtgaaactt
    22261 atatagaaca aagccccccc cctgtcctct cgattttgag aggcaggggg aataggcaaa
    22321 acttaagttt tttcaatata tgatttttaa tcttgatata atttcatacc catccattgt
    22381 ttcatgtgat cgagcatctt gtcatccggt tcgatcaaaa cacaggaatt tttctgctcc
    22441 agggaaatca tgatcgcgta tactttggca gccgcctcac ctgaggtaaa gtcatatgtc
    22501 ttttccgcat ggtaggactg caagcgcgga gattttgcag gagcgatgat ctctgcctgc
    22561 tggatgtcaa atcccagttt tgcttttctt ttggctttgc tataaatggc atcgatctgt
    22621 atatcatggt ttaaaataga atactcatat tccacattca ggcgtggaaa gatgatatag
    22681 taagcaagaa atcctaccac gagtgccggg agtaaagcga gcataccgat caaaggcatg
    22741 ccaaagaaaa tgatcgcgac gatcaggagt acgatcagga tcctgacaag caaatcatag
    22801 ggtctgggtt tccgggcaac aatttgttca tacatagcat cattcataat taaaggttcc
    22861 tttctgtctg taaatagttc atgaccatca tggcgatctt aaatgtcatt gcatcttcaa
    22921 atcttctaat atccagacct gttcgttttt ctacctgttc caatcgatat ataagcgtat
    22981 tcctgtgcat atgcagctgt ctggacgttt ctgctatatt cagattattt tggaaaaact
    23041 tattgatcgt gacaactgta tcttcttcaa atgtgtgagg aagttcttcc ccaaaaagtt
    23101 ctttcaagaa gttttcacat aacggtaccg gaagctgata gatcagacgg cctatgccca
    23161 atttgttata gggaaacaca gtttgttctg agaaaaagag tttcccgact ttgagggcaa
    23221 gactggtttc ttcataagcg cccggcaagt ctgccagaga atgaagaaga gaactaaaag
    23281 acacctgcac atggatcagc gcttctgtat tcaatgtatc tacaatcatc cgcgcgcttt
    23341 tggtacaatc atccggactg ccttctgttg gggctgccgg ttttaaaaca gcgattcttt
    23401 gcgcgtttac ggggatcaga taggtctttg cctgtgcagg aaatatattt tttaaaatct
    23461 ccagtacagt atcatcatag gcggttttcg tttctaaaag aaataaaatc cgcaattgtt
    23521 ccgactgaat atgcagacga gacgcgcgtt ccttaagctc gcatgtctgg atgttcccgc
    23581 ttaagaggct gtataaaaaa tctgttttat tatacttctc tttataagca gtggtcagac
    23641 agtgaatctg tctgactgct gcttccatct cctcattgga agcagggtgc atatctaagg
    23701 aaataccggt aatccttttt aactcgccca gtgccttctt taatgcaggt gtctgttcca
    23761 taaatacctc ttccatacaa tgtttttata aaaaaggccg cacatgaagt gcagcctttt
    23821 agtattttag gtcatcatct gtgcagtatg tatctgcacg gaatagcttc ttcgcgttcg
    23881 ctaagctgct attcttcatt gtaatgcatt agtttgtaat cgtcaattca gtttctttgt
    23941 caaaaagatg aatcttttcc atatccagag caaacacagc tttgtctcca gttcttaaag
    24001 ttgtacgtgg atttacacga gcagtcatct gtgtaccttc tacatcgaaa tacaagtaaa
    24061 cttctgcacc aagaagttcg tacactttga tcgtagattt gatgacactt tcaggagagt
    24121 tgctgataaa tgcctcagaa tcatgtacat cttccggacg gataccaaga acaactgtct
    24181 ttccgtcgta accgccgtcg atcagagctt gtttcttaga agctggaact ttcaatacat
    24241 gttctccgat agtcagagta acgtcatttc cttttacgcc tacaacagcg tctaagaagt
    24301 tcatctgcgg agaaccgata aatcctgcaa caaataaatt gcaaggtgta ttgtacaggt
    24361 tctgcggtgt atctacctgc tgtacgacac cgtctttcat aacaacgatt cttgtaccaa
    24421 gtgtcatagc ctcggtctgg tcatgtgtta cgtagatgat cgttgcgccc aggttttcat
    24481 gcagcttgga aatctcgata cgcatctgca ctcttaattt tgcatccagg ttggaaagtg
    24541 gttcgtccat aaggaatact tttggattac gaacaatcgc acgtcccatg gcaacacgct
    24601 gtctctgtcc gccggagaga gcttttggtt tacggtcaag aagtttttcc agatcaagga
    24661 tacgagctgc ttctttgacc tttttatcaa tttcagcctt aggtacttta cgaagcttca
    24721 gaccgaaagc catgttgtca tatacagtca tgtgaggata cagagcgtag ttctggaata
    24781 ccatcgcgat atcacggtct tttggctcta catcgttcat gacctttccg tcgatctcaa
    24841 g
//
