LOCUS       NC_022571.1            23825 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_022571.1 Clostridium saccharobutylicum DSM 13864, complete
            sequence.
ACCESSION   NC_022571
VERSION     NC_022571.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:58:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1668207
            Orig. end    :: 1692032
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1404
                     /locus_tag="ctg1_1406"
                     /transl_table=11
                     /translation="MEGHKSKRSKVALGIIMFLCCLAAIYLGISAYFIKHFYLGSTINS
                     MNVSGKTVEEVNEKMSSEIQNYSLELQEKGDVKEQIKGSDIDVKYSQDGESKIKSLKDN
                     QNPLGWISGVFGKKNNETTELISYDEQLLNKVLNGLPGINSKNVVESKDASFEYGDGGY
                     KIVNEVYGNKIDKEVLKQKVSDAIVKEDTTLDLDSSDCYKKPKYTADSQEVTDAKNTLD
                     KYTNVTITYASGNNKEVVDGSAIHNWLSVDDDMQVAFDEKKVKKYVSTKLGSTFNTFGK
                     TRDFTTTSGSKVKVSGGDYGWLIDSTKETKDLIETIKSGQSTTKEPIYAQKAVSSDKND
                     IGNTYVEVNFTKQHVWFYKNGSLVTDGPCVSGNVSLKLATPPGTYALNYKEKNATLKGE
                     DYSSPVTYWMPFNGNVGLHDASWRSPNEFGGSTYLTSGSHGCVNLPVELAHKIFDNIEA
                     GTPVVCYNE"
     protocluster    1..23825
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1678090:1682305](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9884..14098
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..23825
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23825
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="6"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             1805..3190
                     /locus_tag="ctg1_1407"
                     /transl_table=11
                     /translation="MEISKNQCSKLLVGIIISLCTLIGIYFWISIFFINHFYFGSTINC
                     FNVSGRTVEQADEQISSEIDSYSLKLEERGGEAEQINGNDIDLKYNLDGKIQSFKDKQK
                     PFAWIPGIFTSKDSKSSDIVNYNENLLKKSVDKLSCLDNNTVEPKNVSFKYTDKGYEIV
                     DEVYGNKINKDALYQSIKNAISNGEKAINLESANCYENPKYTSKSKEAIDTKNLLNDYV
                     NTTITYNFGDKTEVLNGATINNWLQVDDDLGVTFDEKEVKKYVDTLASNYNTVGKPRDF
                     VTTAGLKIKVSGGTYGWEINKSEEVKDLISLIKDKKSTTKEPIYSQKGISHDLNDIGNT
                     YVEINMTRQHLWFYKNGSLVTDGPVVTGNVSGGCGTPAGVYKLNYKERNATLKGQGYSS
                     PVSYWMPFNGGIGIHDANWRSVFGGNIYRTSGSHGCVNSPYSLAQSVYQSIDEGTPIVC
                     YYE"
     CDS             3774..4610
                     /locus_tag="ctg1_1408"
                     /transl_table=11
                     /translation="MLTIGCHLSSSKGFENMGMDALKIDANTFQFFTRNPRGSKAKDID
                     KEDVKAFLKLAKQNNFGRILAHAPYTLNACSADEKNRNFAIEIMSDDLNRMEYVPNNLY
                     NFHPGSHVKQGVEIGINYIVEALNTILKPEQTTTVLLETMSGKGTEVGRNFEELAEILR
                     RVDLKEHMGVCLDTCHVYDAGYDIVSNLDGVLEEFDKIIGIEKLRAIHLNDSKNPFESH
                     KDRHETIGEGFIGIEAISRIINHPSLRELPFFIETPNELEGHAKEIELLRTMYQNF"
     CDS             4813..4986
                     /locus_tag="ctg1_1409"
                     /transl_table=11
                     /translation="MNVETRSCDKNYIDLVKTDSILEDKKKCSLKEEGIIRSCDECGLK
                     CVCDGISMLSIY"
     CDS             complement(5073..5954)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58.2; E-value: 2.1e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1410"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-33,
                     bitscore: 113.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.5e-16, bitscore: 58.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLNQLYYFKTVAKLEHYGKASEVLNISQPSLSYAISSLEDELGT
                     YLFEKQGRNIVITKYGKVFLKYVEDSLEQLELGKKKIKQLTNAAYGQIDISFIYTLAPD
                     FIPKTVRNFLNVSENKDITFTFNQGITSEIITGLKEEKYDVGFCSYVKDESDIEFIPII
                     EQELVAIVPTDHELVNRTSIDLSEIANFPIITYSRNTGLGQVTLDLFERINVSPNIVYE
                     AEEESAIAGLVSHNFGIAIVENIPLIKQFDVKSIPISNPKYKRHIYLAYVKNKFLPPAV
                     RKFINFFHPIHF"
     CDS             6274..7035
                     /locus_tag="ctg1_1411"
                     /transl_table=11
                     /translation="MNVVEVKGIKIGEGIPKICVPIVGGTNAELIEEAKSLKGIKLDLV
                     EWRVDFYENVEDIEKVKEILKELVEVLGNTPVLFTFRSKKEGGEREVSTEYYVKLNCEI
                     AKTKLIDLVDVELFTGNEFVNEVVETAHNNGVKVVMSNHDFFKTPAKEEIVSRLSKMTE
                     LNADLPKIAVMPQNEADVLTLLCATNEMKQKYPEKPIITMSMAGMGVISRLAGEFFGSV
                     LTFGAAKKASAPGQIGVEDLYSVLQLLHRSK"
     CDS             7250..8152
                     /locus_tag="ctg1_1412"
                     /transl_table=11
                     /translation="MNDNILLESGTGELEIIEFVVNGNHYAINVVKVKEIIGMPTNGVT
                     KLPDPKPEIAGLILCRDEILTLVDLKYIITKQMRGNVGSKVIICEFNKVKVAFSIDDVV
                     GVHRIKWNEIRKPDDLSDNSLSVGNILLGGKVLIMLDFEKIVTDICPSAGISEDRLVKV
                     EYKDRSNIKLVLADDSALIRRLLKETLTKAGFKNLRIFDNGQQALDFLNELKESKGEDF
                     DQDAQMLITDIEMPQMDGLTLTRKIKEDPILKKLPVVIFSSLITNELRHKGESVKADAQ
                     LSKPEVEELVDTIDKLLNM"
     CDS             8467..9369
                     /locus_tag="ctg1_1413"
                     /transl_table=11
                     /translation="MSKKVTFLCDLKSGKTIKISLMVMKIIFKDLSKIVCILGDKSGEI
                     KANIPNKKGDIVEGRVLEIEGIKDGNLEVQKYEFISEYQIEDYLRTVNRPIEEIMDEIE
                     LYTNKYIISREAKALNDYFFKNEEFLEKFKKGIGGVSMHHNYIGGLAEHTLNVMYLAAI
                     LCKRYECRRTETTILAAKLHDIGKIYELYYNGPFKYTLRGEMEGHIVIGVEMLDEAIRK
                     NPSFYSEDFVTRIKGCIVQHHGKLEYGSPREMKMEEAFILNYADSIDATMNKISRLKDK
                     TEIGTWSEYDRTIESKLYL"
     CDS             9884..14098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1414"
                     /sec_met_domain="HGD-D (E-value: 2.6e-36, bitscore: 124.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.1e-38, bitscore:
                     131.2, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLLRVGIDIGSTTIKMVVVGGQENIIYKTYRRHLADIRNAFKG
                     CLEDAKEFVKDSKLAVSISGSGGLSLAEKLNVEFIQEVIASTKAIQKQNPDTDVVIELG
                     GEDAKITYLNGGVEQRMNGTCAGGTGAFIDQMAALLNMDASRLNEVAKEYENIYPIAAR
                     CGVFAKTDVQPLINEGAKKADIAMSIFHAVVVQTISVLACGRPILGKVAFLGGPLTFLS
                     ELRKRFIEVLELKEEEVIFPEDSELYVALGAALSCDTKKSTNYENILEKLEEAKNREEE
                     KANSLDPLFKNAQEYEEFKSRHGKSVVKEANIEDAKGNCFLGIDAGSTTTKATLINEQG
                     EILYSYYASNKGNPVNTAVEILKEIYEKLPKDTKIINSGVTGYGEALLKEAFGIDIGEI
                     ETVAHYKAAKFFCNDVDFILDIGGQDMKCLRIEDGTIQSITLNEACSAGCGSFLQTFAK
                     SLGLDIKDFAKKAIFAKSPVDLGSKCTVFMNSKVKQAQKEGFEVDDIAAGLAYSVVKNS
                     LYKVIKLRNPDELGNNIVVQGGTFYNEAVLRSFELLSKRQVVRPNISGLMGAFGAALLA
                     KERYEEGYQTSLVKKENVDKVQMKSTTVRCGKCSNNCLLTVNKFENGNRFIAGNKCDAP
                     LGMDKNKEEIPNLYEYKYNRLFSYVPLKEKEAKRGIIGIPRVLNIYENYPLWFTLFTEL
                     GFRVELSSKSSKKIYEKGLTSIVSETACYPAKMVHGHVEDLIEKGIKNIFYPCILNEKM
                     EFENVTNTFNCPVVTSYAEVIKNNLESIKSNNVNFMNPFLPIADKSKLKKRLKEVLGGF
                     GISQKEINNGIDKAWEVQEEFKNDIRNKGIETLNYIKQHNIKGILLSGRPYHVDPEINH
                     GMPKLINSLGMAVFTEDSIAHLGKVQGELNIVDQWAYHSRLYRASSYILDRDDIELVQL
                     TSFGCGLDSITTDQVSEILHSASKIYTNIKIDEGSNLGAARIRLRSLKAAIQERENNNF
                     VRVRKELEESNNYINPGKKGTIIVPQFSPIHFNMLEAVFNESGYNLVILQNDNNAIEEG
                     LKYVNNDICYPAIVVIGQLIDALKSGEYDLNNTSILLAQTEGQCRFTNYVKVLEKGLKE
                     AGFNNIPVLSLSLAGLKKANGLEGMNFDLLKKSIVGVIYGDLLSKVLHRVRPYEKVKGS
                     ADELYKKWSEICRESFKEPIKKNFRNIIIRIIKEFENLPRIEMDKPKVGLVGELLVKFN
                     PIANNNIVHMLEGEGVEVVHNDLLSLFLASAKNQIFNHKHLDGKYINKIKGQLTISFIE
                     KYQKVYLDALKKSGIFYVTETIDELANNASKILSLGNQSGEGWKLPGEIMELCSWGVDN
                     VVCMQPFGCLPSHAVARGTIKALKKQNENLNIVTIEYDPGSSEVNQTNRIKLMLASAFN
                     KI"
     CDS             14288..15136
                     /locus_tag="ctg1_1415"
                     /transl_table=11
                     /translation="VEKIALLTDSASDISMELLQKNNIKLLPFKIIYKDKEYDDRIEIT
                     PHMMYERLENEIPKTSLPSIEKMTNALQQAVEEGCTHAIIITISSAFSGTNNAARIVCE
                     DFKDIETFVFDTKTLSAAQGIMVLKTAEMIRSGKSFKEITEVLPTFRDKIDSYFALDTL
                     EYLKKGGRIGAVAGTVGEFLNLKPIITVADDGTFMGIGKVRGSKQALSKLISILKGYLD
                     KGKHSVWIVNGNAADKVQWLMDNIKDLPNLVECNVAGITGPALGVNTGSGSVGIVIEKV
                     D"
     CDS             15637..16926
                     /locus_tag="ctg1_1416"
                     /transl_table=11
                     /translation="MFKRKLLIVSTMAVTLALGCFVPGKEAKAADNSWNLVWGDEFNGS
                     TINTNNWTYDIGTGSGGWGNNELEYYTNRPENARVENGNLVIEARKESYGGMGYTSARM
                     KTQELQNFTYGKVEARMKLPAGQGIWPAFWMLGKNIPQVNWPACGEIDIMEHVNNESST
                     HGTIHWDYNGHQSYGTTSPNIDVTQYHVYSVEWDKDAIKWFVDGTKYLEANISNNINGT
                     DEFHKPFFILFNLAVGGEWPKNPDGSTAFPAKMYVDYVRVYQGNGGSQTQPTSSKLPSN
                     TWYLFNQSVTGVGASSQDMQIGKAGVSGWQPTKNVNAGYNLWTTPTINGTYNAGKWNFT
                     LWTNNPGTSNIAVDLYKVNNDGTGETLLGSQTVDVSKTGGGNHPTVYSYNLGQVSLANQ
                     RLRVKIHKVSGADAVMCYNTNDFSTKLVTP"
     CDS             17191..17742
                     /locus_tag="ctg1_1417"
                     /transl_table=11
                     /translation="MERVFDQFNYGNVFITGGVNKGKTSILATLMENCIDKGENIYFID
                     AEYELSKVFDKYDNVKSLFVSSNVVKVKQFVSDMNNGDTLIIDAYGMLSSSVKSYIKKF
                     LATNKYRAIIASKNANDISVTQFTNVIALGTTRSFSKHIGVDTSTLASDEVLINGDKII
                     KFNYSEFIGYKAGLVISRMK"
     CDS             18302..20782
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1418"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.2e-59, bitscore:
                     198.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 2.3e-12, bitscore:
                     45.1, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVIIVGGVAGGASTAARLRRLDENAEIIMIEKGEYISFANCG
                     LPYYIGGTINEREKLIVQTVEEMSAKFNLDIRNLSEVIRIDKDNKKIKIGNKKNGEIYE
                     EGYDVLVLSPGANPLKPPIPGIEECDNLFTLRNIPDTDKIKSYVDNKKIKNAVIVGGGF
                     IGLEMAENLHERGINITLVEASNQVMAALDIEMVSIIHEHLIDKNIQLILNDGVKSFDN
                     KGKKIILSSGKEIDADMIILSIGVKPETAIAKDANIKINEKCAIVVDKNMKTSDPNIYA
                     LGDAVEIMDFVNKKPTMIPLAWPANRQGRIVADNICGKNVEYKGSLGSSVAKVFDYTVA
                     TTGNNEKTLKRLGIEYKAIHIHPGSHAGYYPGAFPIAFKMLFDPKNGTIFGAQGVGMDG
                     VEKRIDIIATAIKGNLNVFDLQDVEVCYAPPYNSAKDPVNMLGYYASNIIDGIVDIIEW
                     DQIDKLDKKNSIILDVREEFELATGTFDNYMHIPLGELRNRLNEIPKDKDIYVTCQVGL
                     RGYVGCRLLEQHGIKCTNIDGGIKTYFYVKNAEKSIRDQHERNKDIKEEVAVMSLEDLD
                     ITEINAKVTLNACGLQCPGPIRKVFEEISKMEDEEILEVKASDPGFSKDIKSWCEKTNN
                     TLLKSEFNKDEKAFVAYIQKGTNKKQESSTALTAEKNGATLVVFSGDFDKAIASFIIAT
                     GAASMGKEVTMFFTFWGLNILKQKNKPKVNKDSMEKMFDIMLPGHAGKLPLSQMNMMGM
                     GPTMIKQIMKKHNVDDLETLITNAIKMGVKVVACSMSMDLMGIKKEEFIDGVEIGGVAS
                     YLGATEDSGLNLFI"
     CDS             20880..21167
                     /locus_tag="ctg1_1419"
                     /transl_table=11
                     /translation="MKILLMKVKLRASWVHSLKEKRMIVKSIVQRLRNKFNISVCEVEC
                     QDMHQTIVIGITGICGSSSQMDSTIENIITFIECNTDAEIIDIQAEEDVL"
     CDS             21558..21890
                     /locus_tag="ctg1_1420"
                     /transl_table=11
                     /translation="MKCMCKIDNPLETPFGYTISMIGGKWNLIILHQLKRNSVMRYSEL
                     KRTLTGITHKMLSQKLKELEGNKLIIRKEYPQVPPKVEYSLSERGLSLSKIMQDICEWG
                     HAHSND"
     CDS             complement(22170..23825)
                     /locus_tag="ctg1_1421"
                     /transl_table=11
                     /translation="MKIKIHNTSLKTAISVMLAIAIIIVTTFTEGINAYAASLNVKDNG
                     STIVVDTGSGLVYTINKANGDMTSCKLNGTELNAKNKASQISSGLGSAHVTWSTFSSGS
                     QVLITCSTNTLTQYYASKYGDNTIYMSTYITAEPSVNELRYVFRGDMNVLKNVPTYSDI
                     RGNNGAIESTDVYGFSDGHTASKYYGNDQAKDLTIKGATGNNVGVFMAYGNRETSSGGS
                     FQRDIQFQTAYPDNMNTEITNYMNSTHAKTENFRSGLFGPYALCFTNGSTPSLPDYKWM
                     ATLGLKGYVADSNRGKVTLNGLSGMDTRYTYTIGFANSTAQYWAKASSTGAATCSGMKA
                     GKYTMTVYKGELGVYTESVTVTARGTTTIPTRTITADPSKTPTIWRIGNWDGTPLEFLN
                     GSNIQYRHPSDKRNASWGPTTFSVGSADNKFPAAQFRGANSPTTVTFNLTHGQAAAGHT
                     LKIGITTAYNNGRPSVTINGHALPNLSAPIEPGQRTLTVGTYRGNNATLAWNIPSSYFV
                     AGSNTITIKPVSGSSDISAYLSASYAYDCLELDN"
ORIGIN
        1 atggaaggac acaaaagcaa gcgcagtaaa gttgcattag gaattataat gtttctttgt
       61 tgtttggctg ccatatattt aggtatatca gcatatttta ttaaacattt ttatcttggt
      121 tctacaatta attccatgaa tgtttcagga aaaacagtag aagaagtaaa tgaaaaaatg
      181 tcatctgaaa ttcaaaatta ttcattggaa ttacaagaaa aaggtgatgt aaaagaacag
      241 attaaaggtt cggatattga cgtgaaatat agtcaggatg gagaaagtaa aattaaaagt
      301 ttaaaggata atcaaaatcc tttaggatgg atttcaggag tatttggtaa aaagaacaat
      361 gaaactactg aattaattag ttatgatgag caattattaa ataaggtttt aaatggttta
      421 ccaggtatta atagtaaaaa cgtagttgaa tctaaagacg ctagctttga atatggagat
      481 ggtggttata agatagtaaa cgaagtttat ggaaataaaa tagataaaga agtgttaaag
      541 caaaaggtat cagacgcgat tgtaaaggaa gatactacat tagacttaga ttcaagtgat
      601 tgttataaaa agcctaaata tactgcagat tctcaagaag ttactgatgc taaaaacacc
      661 cttgataaat atacaaatgt aacaattact tatgcttctg gaaacaataa ggaggttgta
      721 gatggatcgg caatacataa ttggcttagt gttgatgatg atatgcaagt tgcgtttgat
      781 gaaaagaaag tcaagaaata tgtatctact aaattaggta gtacgtttaa tacatttgga
      841 aagacaagag atttcactac aacatctgga agtaaagtta aggttagtgg tggtgactat
      901 ggatggttga ttgattcaac taaagaaaca aaggatttaa ttgaaactat aaaaagtgga
      961 caatctacta caaaagaacc aatatatgct caaaaagcag tatctagtga taagaatgat
     1021 attggaaata cgtatgtaga agttaatttt acaaaacagc atgtatggtt ttataaaaat
     1081 ggatcattag ttacagatgg accatgtgtt tcaggaaatg taagtttaaa attagctact
     1141 ccaccaggga catatgcatt gaattataaa gagaaaaatg ctacattaaa gggtgaagac
     1201 tatagttcac cggttactta ttggatgcct tttaatggga atgttggtct tcatgatgca
     1261 agttggagaa gtccaaacga gttcggagga agcacttatc taacaagtgg ttctcatggt
     1321 tgtgtaaatt taccagttga attagcacat aagatatttg ataatattga agcaggaact
     1381 ccagtagttt gctataatga gtaataaaat taaacatctc gtatcttaaa aatttatatt
     1441 tattagtttt gacctctata atacttagaa ttaagtatta tagaggtttt ttgtgcttta
     1501 gccccaaaaa ttacatgcta ttcaggtggt tagcggtgat tagaacttaa aaaaatattt
     1561 ttatcgtaaa ctttactttt taacaaaacg aaaactggca gtatcaataa aacttaagtt
     1621 tggtaacaaa gttcttttaa agcaaaaata aatttttaaa taacttttta taatatagag
     1681 caaaaaacaa ttggaaaaaa attcaaaaaa atatataata taagaatata gattatattg
     1741 cttgtttttg aaaagtatgt gttttattaa atcttagttc taatataggg ggataacaat
     1801 tattatggaa atatcaaaaa atcaatgtag caagctatta gtaggcatta tcatttcact
     1861 ttgtactttg attggtatat atttttggat atcaatattt tttatcaatc atttttactt
     1921 tggctctaca attaattgtt ttaatgtttc aggaagaaca gtggagcagg cagatgaaca
     1981 aatatcatca gaaatagatt cgtattcctt aaaattagaa gaaagggggg gagaggcaga
     2041 acaaattaat ggaaatgaca ttgatctaaa atataactta gatgggaaaa tccaatcttt
     2101 taaagataag cagaagcctt ttgcatggat tccaggaatt tttacatcta aagattctaa
     2161 atcatctgat atagttaatt ataatgagaa cttactaaaa aaatctgtag ataaactttc
     2221 ttgtcttgat aataatacag ttgaacctaa aaatgttagt tttaaataca cagataaagg
     2281 ttatgaaatt gtggatgaag tttatggaaa taaaatcaat aaggatgctt tatatcagag
     2341 tattaaaaat gcaattagta atggagagaa ggctataaat ttagagtcgg ctaattgtta
     2401 tgaaaatcct aagtatacat caaaatctaa ggaagctatt gatactaaaa atcttcttaa
     2461 tgattatgtt aatacaacaa ttacttataa ttttggtgac aaaacagaag ttctaaatgg
     2521 agctacaata aataactggc ttcaagtgga tgatgatctt ggagttacat ttgatgaaaa
     2581 ggaagttaaa aagtatgtag atacattggc tagtaattat aatacagttg gtaagccaag
     2641 agattttgtt acaacagcag gattaaaaat aaaagttagt ggaggaactt atggttggga
     2701 aataaacaaa tctgaggaag taaaagattt aatttcgctc ataaaagaca aaaaatctac
     2761 aacaaaagag ccaatatatt ctcaaaaagg aatatctcat gatctgaatg atataggaaa
     2821 tacttatgta gaaattaata tgactagaca acatttgtgg ttttacaaaa atggatctct
     2881 tgttacagat ggaccagttg ttacaggtaa tgtaagcgga ggttgtggaa caccagcagg
     2941 cgtttataag ttgaattata aggaaagaaa tgctacatta aaaggacaag gctatagttc
     3001 tccagtaagt tattggatgc catttaatgg aggaatagga atacatgatg caaattggcg
     3061 ttcagtattt ggaggaaata tttataggac aagcggttct catggatgcg taaattcacc
     3121 atattcttta gcacaatcag tatatcagag tattgatgaa ggaactccaa tagtttgtta
     3181 ttatgaataa tactatctat ataatttaat taatgattta taaaaatata tttaaaagtg
     3241 gttacttaaa aatacaaaat tagtacattg atatagataa ataacttata acttaaagtt
     3301 atgcgatagt taacctaaac agagatcatg catttattca gttactgaaa agcatgatct
     3361 ctatttctat ttttttggat atgtattaaa aattaggaac attaaattaa cgttgataaa
     3421 tgataatcct ttagtggtgt taaattaaac ttaacaagaa actaatatat tttaatttga
     3481 aagaaaatta agtgaatttg attataaaat atgttgatat tgaagaaaaa gaagtttgag
     3541 ttattaatta atagtattta ttaattgatg tattatataa aatatgctaa taataagagt
     3601 attaaggcac gcgaaaataa ataataagtc taatttgccg tgaatatttt tcatcaggta
     3661 aataggagca gcctattagg taaatttgcc gacgtatcat tatggtaaat aggctggcaa
     3721 atggacacgt tatttttttg aatgtgccta atataagaat ggaggaaata catatgttaa
     3781 ctataggatg tcatttatca tcttctaagg gatttgaaaa tatgggaatg gatgcactta
     3841 aaattgatgc taatactttt caatttttta cccgtaatcc aagaggaagc aaagctaaag
     3901 atatagataa agaagatgtc aaagcttttt taaaattagc aaaacagaat aattttggac
     3961 gtatacttgc tcatgcgcca tatacattga atgcttgttc agcagatgag aaaaatagga
     4021 attttgcaat agaaataatg agcgatgatt taaatcgaat ggagtatgtt ccaaataatt
     4081 tatataattt tcatccagga agccacgtaa aacaaggagt tgaaattgga attaattata
     4141 ttgtagaagc attaaacact attctaaaac ctgaacaaac aacaacagtt ttattagaaa
     4201 ctatgtcagg taaaggtact gaagtaggta gaaactttga agaattagca gaaattctta
     4261 gaagagttga tttaaaggag catatgggag tatgtcttga tacatgtcat gtttatgatg
     4321 caggatatga tattgtaagc aatttagatg gtgtattaga ggaatttgat aaaataattg
     4381 gaattgaaaa gttacgtgca atacatttaa atgatagtaa gaatccattt gaaagtcata
     4441 aagataggca cgaaactatt ggagaagggt ttattgggat tgaggctatt tccagaatta
     4501 taaatcatcc aagtttgagg gagttaccat tttttattga gacacctaat gaacttgagg
     4561 ggcatgcaaa agaaattgag ttattgagaa ctatgtatca aaatttttag taacagaaat
     4621 aaatgatctt tatttctgtt aaccatagca taagtttaag ttataaggtt tttatctata
     4681 aaataattta atggctaatt tctaaaaaat aattaaatat aaattaacaa aaaagacatc
     4741 tattcttaat gaattatatt aatagaattg gatatatttt attaataagg aacaattagg
     4801 agttgatgta gaatgaatgt agaaacaagg agttgtgaca aaaattatat tgatttagta
     4861 aaaacagatt ctatattaga ggataagaag aaatgctcat taaaagaaga agggattatt
     4921 agaagttgtg atgaatgtgg acttaaatgt gtttgtgatg gaatttctat gctgtcaata
     4981 tattaaaaaa aatatttctt taggcatatt aaaaaagtaa caaataagaa tactagttta
     5041 catgttattt tcttttatat gcctaaaatg aattagaaat gtatagggtg aaaaaaatta
     5101 ataaatttac gcacagctgg tggtaaaaac ttatttttta catatgcaag ataaatatgt
     5161 cttttatatt ttggatttga aataggaata gactttacat caaattgctt aattaatgga
     5221 atattttcta ctatagcaat tccgaagttg tgagaaacaa gacctgcaat tgcactttct
     5281 tcttctgctt cataaactat atttggacta acattaattc tttcgaatag atctagagtt
     5341 acttgcccca atccagtatt tcggctatat gtaataatag gaaagtttgc aatttctgat
     5401 agatcaatag aggtacgatt tactaattca tgatcagttg gaacaattgc aaccaattct
     5461 tgttctataa taggtataaa ttcaatatcg gattcatctt ttacatatga gcaaaatcca
     5521 acatcatact tttcttcttt taatccagta ataatttctg aagtaatacc ttgattaaat
     5581 gtaaatgtaa tatctttatt ttcacttaca tttaaaaaat ttctcacagt ttttggaatg
     5641 aaatctggtg ctaaggtata tataaatgaa atatcaattt gtccataagc agcattagtt
     5701 aattgcttta tctttttttt tccaagttct aactgttcaa gagaatcctc tacatatttt
     5761 agaaaaactt ttccgtattt agttataact atatttcttc cttgcttttc aaataaatat
     5821 gtacctaatt catcttctaa tgaagatatt gcatagctca aactaggctg agagatatta
     5881 agtacttctg atgctttgcc gtaatgttca agcttggcca cagttttgaa gtaataaagt
     5941 tgatttaaat tcatactata agcctcctta catgtaaaat ataataacat aaatgtttag
     6001 atattagaat gtataaaaaa taacaaatga taattatatt tgaaatattg tgaatattat
     6061 ttaaacaata ttataataca tcaatattat ttaaataact catacaataa ttctattaat
     6121 aatatataaa atatttatta gattatttct gtattggcat ttataataaa aacataaaag
     6181 aattgttatt tattataaag ttatttgtta tatatttaac gaaaagttat ataataaata
     6241 aatttttcaa aacatttagt ggagggatat aacatgaacg tagtagaagt taaaggcata
     6301 aaaatcggag aaggaatacc taagatttgt gtaccaatag ttgggggaac aaacgcagag
     6361 ttaatagaag aagcaaaaag tttaaaagga attaaattag atctagtaga atggcgtgta
     6421 gacttttacg aaaatgttga agatatagaa aaagtaaaag aaatacttaa ggaattagtt
     6481 gaagttcttg gaaacactcc tgtattattt acatttagaa gtaaaaaaga aggaggagaa
     6541 agagaagtat ctactgaata ttatgttaaa ttaaattgcg aaatagctaa gactaaatta
     6601 atagatttag ttgatgttga attattcaca ggaaatgaat ttgttaatga agtagtagaa
     6661 actgctcata ataatggagt taaagttgta atgtcaaatc atgatttctt taagacacca
     6721 gctaaagaag agattgtttc tagattaagt aaaatgactg aattaaatgc agatttacct
     6781 aaaatagcag taatgccaca aaatgaagct gatgttttaa ctttattatg tgctacaaat
     6841 gaaatgaagc aaaagtatcc agagaagcct ataataacta tgtcaatggc aggaatgggt
     6901 gttataagta gactagctgg agaatttttt ggatctgtat taacatttgg agcagctaaa
     6961 aaagcatctg cgccaggaca aataggagta gaagatttat attctgtact tcaattatta
     7021 catagaagta aataatctga taaaaaagga taaattacta tacatttgct tatttaaaag
     7081 ttataatata attgataaaa aatgttatta aaacccacta agtgttctta gtgggaattt
     7141 tataaaaaaa tatggtgaaa aagtggaatt attttaagga aaaatgaatt aatatgttag
     7201 aatactatat taattgtatt atataaactt taagtaaggg gtagatatta tgaatgataa
     7261 tatattatta gaatcaggta ctggagaatt agaaataatt gagtttgttg taaatggaaa
     7321 tcattatgca attaacgtag taaaggtgaa ggaaataata ggaatgccaa ctaatggggt
     7381 aactaaatta ccagatccta agcctgaaat agctggactt atattatgca gagatgagat
     7441 tcttacacta gttgatttaa aatatattat aacaaaacaa atgagaggaa atgtaggttc
     7501 taaagttata atttgtgaat ttaataaagt taaagttgca tttagcattg atgatgtagt
     7561 aggagttcat cgtattaaat ggaatgaaat aagaaagcca gatgatttat cagataattc
     7621 attatctgtc ggaaatatac ttttaggcgg taaagtacta attatgcttg attttgaaaa
     7681 gattgtcaca gatatttgtc caagtgctgg aataagtgaa gatagacttg taaaagtaga
     7741 gtataaagat agatcaaata taaagttagt tttagccgat gattctgctt taatcagaag
     7801 acttctaaaa gaaactctta caaaagctgg atttaaaaac ttaagaattt ttgataatgg
     7861 gcaacaagca ttagattttc tgaatgaatt aaaggaatca aaaggcgaag attttgatca
     7921 agatgcacaa atgctaataa cagatataga aatgccacaa atggatgggc ttacacttac
     7981 aagaaagata aaagaagatc ctatattgaa aaagttacca gttgtaatat tttcatcatt
     8041 aattacaaat gaattaaggc ataaaggcga atctgttaag gctgatgcac aattaagcaa
     8101 gccagaggta gaagagcttg ttgataccat agataagtta ttaaatatgt agataattaa
     8161 taatcaaata ataatacatg tataaaaaat aagtcacttt aaaattgtta tatagtaatt
     8221 ttaaagtgac ttattttttg ctttattcta atatgaagaa attgtaatat ttttaataaa
     8281 tgaaaatctg attttatcta ggcttaatac tattgatgta tataaattaa ttctgaaaag
     8341 ttaaaaaatt gataatgaag aatggcacat aaatttttta tattataaag ataagttgaa
     8401 ttattatttt ataagtagtt tttacacata atatgtttgt aaattaaatt ttatttggag
     8461 ggaaatatga gtaaaaaagt aacattttta tgtgatttaa aaagtggaaa aactataaaa
     8521 atatcgttaa tggtgatgaa aataatattt aaggatctta gtaagattgt atgtatttta
     8581 ggagataaga gtggagaaat aaaagccaat ataccaaata aaaaaggaga tattgtagaa
     8641 gggcgggttt tagaaattga aggaattaaa gatggaaatt tagaagtaca gaaatatgaa
     8701 tttatttcag aatatcaaat agaagattat cttagaactg taaacaggcc gatcgaagag
     8761 attatggatg aaattgaatt atatacaaac aaatatataa tttcaagaga agccaaagca
     8821 ctaaatgatt atttctttaa aaatgaagaa tttttagaaa aatttaaaaa gggtataggt
     8881 ggagtatcca tgcatcataa ttatatagga ggtcttgcag aacatacttt aaatgttatg
     8941 tatttagccg ctattctttg taaacgatat gaatgtagaa gaacagaaac aacaatactt
     9001 gcagcaaagc tccatgatat tggtaagatt tatgaattat attataatgg tccgtttaag
     9061 tatactctta ggggagaaat ggaagggcat attgttatag gggttgagat gttagatgaa
     9121 gccattagaa aaaatccatc attttattct gaagattttg ttacaagaat aaaaggttgc
     9181 attgtacaac atcatggaaa gcttgaatat ggatccccaa gagaaatgaa aatggaagaa
     9241 gcatttatac ttaattatgc tgattcaata gatgcgacta tgaataaaat ctctagatta
     9301 aaggataaga cagagatagg gacatggtca gaatatgata ggacaattga aagtaaatta
     9361 tatttataac aattaataaa aaaacaaagg attatttcct ttgctttttt attattcctt
     9421 aataattgat aaatttgaat agcaatatca tgattaagca ttaaatgaat tttatattat
     9481 agatttttat tatatctgtt ttttgtgact gatcaaaaag tagtaaaaat gtttagcaaa
     9541 aacttaaata cttttgatta agtatatata atatatggta taatgcttta tagttaataa
     9601 aataattctc ttaaggcata tgaaaataaa taacaagtcc aaagctgtca tgaatatttt
     9661 tcatcagaca aggaggtaaa gtgtcaacat agtgagtcta ttattgcatt ttgccgacgt
     9721 atgatgatgg aaaatatgca cattaaagaa aagcagctat gctgcataca agaacatttt
     9781 tgccacatcg acttgttatt tatttgattg tgcctaagtt aactaattat aaacaaaaga
     9841 aaaaatttaa tttttaagat tactttactt atgggagaga tatatgaaca aattattaag
     9901 agtaggaata gacattggct caacaactat aaaaatggtt gttgtgggtg gacaggaaaa
     9961 cataatatat aaaacatata gaaggcattt agcagatata agaaatgctt ttaaaggttg
    10021 tttagaggat gcaaaagaat ttgtaaaaga tagcaaatta gctgtttcaa tatcaggttc
    10081 gggaggattg agcttagcag aaaagttaaa tgtagagttt atacaagaag tcatagcaag
    10141 tactaaggct atacaaaagc aaaatcctga tactgatgta gttatagaat tagggggaga
    10201 ggacgcaaag ataacttatt taaacggcgg cgttgaacaa agaatgaatg gaacatgtgc
    10261 tggtggaact ggtgctttta tagaccaaat ggcagcactt ttaaatatgg atgctagcag
    10321 actaaatgaa gtagcaaagg aatatgagaa tatatatcca atagcagcta gatgtggggt
    10381 atttgctaag acagatgtgc aacctcttat taatgaaggt gctaagaaag cagatatagc
    10441 aatgtctata tttcatgcag tagtggtaca aactataagt gttttagcgt gtggaaggcc
    10501 tatattagga aaagtagcat ttttaggagg accattaact tttctttcag agcttagaaa
    10561 aagatttata gaagtgcttg aattaaaaga ggaagaagtt atttttccag aggattcaga
    10621 actttatgtt gccttaggtg cagctttaag ttgtgatact aagaagagta caaactatga
    10681 aaacatttta gaaaaattgg aagaagctaa gaatagggaa gaagaaaagg ctaatagtct
    10741 agatccactt tttaaaaatg cacaagaata tgaggaattt aaaagtagac atggtaagag
    10801 tgtggttaaa gaagcaaata ttgaagatgc taaaggaaat tgctttttgg gaattgatgc
    10861 tggatcaaca acaactaagg ctacacttat aaatgaacaa ggagaaatac tttattcgta
    10921 ttacgctagt aataaaggaa atccagtaaa tacagcagta gaaattttaa aagaaattta
    10981 tgaaaagttg cctaaagata ccaaaattat caattctggt gtaacaggat atggagaagc
    11041 tttattaaaa gaagcatttg gaatagatat aggtgaaata gaaacagtag ctcattacaa
    11101 agcagcaaaa ttcttttgta atgatgttga ttttatatta gatataggtg ggcaggatat
    11161 gaaatgcttg agaatagagg atggaactat tcaaagtatt actcttaatg aagcttgttc
    11221 agcaggatgt ggatcatttt tacaaacttt tgcaaaatct ttaggtcttg atataaagga
    11281 ttttgcaaag aaagctatat ttgcaaaatc accagtagat cttggatcga agtgtactgt
    11341 ttttatgaat tcaaaggtaa aacaagctca gaaggaaggt tttgaagtag atgacatagc
    11401 agcaggtctt gcgtattctg ttgttaaaaa ttcattatat aaagttataa aacttagaaa
    11461 tccagatgaa cttggaaata atatagttgt tcaaggtgga acattttata atgaagcagt
    11521 acttagaagt tttgaattat tgtcaaaacg tcaagttgtt agacccaata tatcagggct
    11581 tatgggcgct tttggtgctg cacttttggc taaagaaaga tatgaagaag gttatcaaac
    11641 ttctttagtt aaaaaagaaa atgtagataa agttcaaatg aaatctacaa cagttaggtg
    11701 tggaaaatgc tcaaataatt gtttgttaac agttaataaa tttgagaatg gaaaccgatt
    11761 tattgctgga aataagtgtg atgcaccact tggtatggac aaaaataaag aggaaattcc
    11821 aaatctttat gaatataaat ataatagatt atttagttat gtacctttaa aagaaaagga
    11881 agctaaaaga gggataatcg ggataccaag agtattaaat atatatgaaa attatccgtt
    11941 atggtttaca ttgtttactg aattaggttt tagagtagaa ttatcatcta aatcttctaa
    12001 gaaaatatat gaaaaaggat taacatcaat agtatcagaa acagcatgtt atcctgctaa
    12061 aatggttcat ggacatgttg aagatttaat tgagaaggga attaaaaata tcttttatcc
    12121 atgtatactt aatgaaaaaa tggaatttga aaatgttaca aatactttta attgtcctgt
    12181 agttacttct tatgcagaag ttataaaaaa taatttagaa tctataaaat caaataatgt
    12241 aaattttatg aatccatttt tgcctatagc agataaatca aagcttaaaa agagattaaa
    12301 agaagtgtta ggcgggtttg gaatttcaca aaaggaaatt aataatggta tagataaggc
    12361 ttgggaagtt caagaagaat ttaaaaatga tataagaaat aaaggtatag aaactttgaa
    12421 ttatataaag caacataaca ttaaaggaat attgcttagc gggagaccat atcatgtaga
    12481 tccagagata aatcatggta tgccaaaact tattaacagt ttaggaatgg cagtttttac
    12541 agaggattcc atagctcatt taggaaaagt acaaggggaa cttaatatag ttgaccaatg
    12601 ggcatatcat tcaagattgt atagagcatc aagttacata ttagatagag atgatataga
    12661 actagtgcaa ttaacgtcat ttggttgtgg actagactca ataactacag atcaggtttc
    12721 ggaaatatta catagtgctt caaaaatata tactaatatt aaaatagatg aaggaagtaa
    12781 tttaggagct gcaagaataa gattaagatc actaaaagca gctattcaag aaagagaaaa
    12841 caataatttc gtaagagtta gaaaagaatt ggaagaaagc aataactata taaatccagg
    12901 taaaaaagga actataatag taccacaatt ttcaccaata cattttaata tgttagaagc
    12961 tgtatttaac gaaagtgggt ataatcttgt tattctacaa aatgataata atgctattga
    13021 ggaaggttta aaatatgtta ataatgatat ttgttatcca gcaatagtag ttataggtca
    13081 acttatagat gcgttaaaat ctggggaata tgatttgaat aataccagta tattgttagc
    13141 gcagacagag ggacaatgca gatttacaaa ttatgttaag gtgttagaaa agggattaaa
    13201 ggaagctgga ttcaataata taccagtttt atctttaagt cttgctggat taaagaaagc
    13261 taatggatta gagggaatga attttgattt attgaagaaa tccatagttg gagttattta
    13321 tggagattta ttaagtaaag ttcttcatag ggttagacca tatgaaaaag taaagggaag
    13381 tgcagatgaa ctttataaaa agtggtccga aatttgtaga gaatcattca aagaacctat
    13441 taagaaaaat tttagaaata taattattag aattattaag gaatttgaaa atttaccaag
    13501 aatagagatg gacaaaccta aagttggatt ggttggagaa ctacttgtta agttcaatcc
    13561 aattgctaat aataatatag tacacatgct agaaggagaa ggcgttgaag ttgttcataa
    13621 tgatttatta tcattatttt tagctagtgc taaaaatcaa atatttaatc ataagcattt
    13681 ggatggcaaa tatataaata aaataaaagg acagcttact ataagcttta ttgaaaaata
    13741 tcaaaaggta tatttggatg cacttaagaa aagtggaatt ttttatgtta ccgaaacaat
    13801 agatgaattg gctaataacg ctagcaaaat cttatctctt ggtaatcagt caggcgaagg
    13861 atggaaattg cctggggaaa tcatggagtt atgtagttgg ggtgttgata atgtagtttg
    13921 catgcagcct tttggatgtt taccatctca tgctgttgca agaggaacaa ttaaagcttt
    13981 aaagaaacaa aatgaaaatt taaacattgt aacaatagaa tatgatccag gttcaagtga
    14041 agtaaatcaa actaatagaa ttaaacttat gcttgccagt gcttttaaca agatataact
    14101 agaagataag atttaggcat aatcaagaaa ataatagacc aatatgcttg cttattttgc
    14161 gatatgttcc gttgataatt tcggttaata gaaattctta gatgaaattg tctacttgtc
    14221 ttacacaaaa tacatgttgc atatttgggc tattattttt atgtgcctta tttaaggagg
    14281 aactaatgtg gaaaaaatag cattattaac ggatagtgca tcagatataa gtatggaatt
    14341 attgcagaaa aataatatta aattattgcc ttttaaaatt atttataagg ataaagaata
    14401 tgatgataga atagaaataa ctccacatat gatgtatgaa aggttagaaa atgaaatacc
    14461 taaaacatca ttaccgagta ttgaaaaaat gacaaatgcg ctgcaacagg cagttgaaga
    14521 gggctgtaca catgcgatta taataacaat atcatctgct ttttcaggaa ctaataatgc
    14581 tgcaagaatt gtatgtgagg attttaaaga tattgaaaca ttcgtatttg atacgaagac
    14641 tttatcagcg gcacaaggca taatggttct taaaacggca gaaatgataa gaagtggaaa
    14701 atcatttaaa gaaataaccg aggttttacc tacatttaga gataagatag attcatattt
    14761 tgcattggat acattagaat atttaaaaaa aggtggtaga ataggggcag ttgctggaac
    14821 tgtcggtgaa tttttgaatc ttaaacctat aataactgta gcagatgatg gaacttttat
    14881 gggaattggt aaggtcagag gatcaaagca agctctttct aaattaatca gcatattaaa
    14941 aggatattta gataaaggta agcatagtgt ttggattgta aatggaaatg cagcagataa
    15001 ggttcaatgg ttaatggata atataaaaga tttacctaat ttagtagaat gtaatgttgc
    15061 aggaataaca gggccagcgc ttggagttaa tacaggatct ggatctgtag ggattgtgat
    15121 agaaaaagta gattaaattt tcaacactaa aaatataact tctgaaattt aaaaaatata
    15181 aatttcagaa gttatttttg ttattcttta gaggcaatta taaggaagtt aaatctctgg
    15241 ataacttttg aaagtagtag aaacacatag tgtgcaaaga aaaaaatgca aagaattgta
    15301 taatttctaa ttacttgaaa gtaattagaa atgtttacgt ttaattcctt attatatgcg
    15361 tttggagaaa tatctatttc atgtaaagta aaatttatat aaaataacta caagtaatta
    15421 ttaaatgaac attcaaattt agttagtaaa aattagcaat actaattaaa aaagaatgga
    15481 ggtgaaaaca tatattgagc tagtgggtta tataaatttt tactaattat aatttgttaa
    15541 ggcatatgaa ataaaataat aaggaaacaa ttgtactgtt attttttgat aatgcctaat
    15601 atgttaatat taaaaattag tttgggggaa aattttatgt ttaaaagaaa attattaatt
    15661 gtgtcaacta tggctgttac tcttgcactt ggatgctttg ttcctggcaa ggaagcgaaa
    15721 gcagcagata attcatggaa tcttgtttgg ggagatgaat ttaatggcag tacaataaat
    15781 actaacaatt ggacttatga tattggaacc ggttccggtg gatggggaaa taatgaatta
    15841 gaatattata ctaatcgtcc tgaaaatgct agagtagaaa atggaaatct tgtgattgaa
    15901 gctagaaaag aatcttatgg aggaatggga tatacttcag ctcgtatgaa aacacaagaa
    15961 ttacaaaatt tcacatatgg aaaagtagaa gcaagaatga aacttccagc tggacaggga
    16021 atatggcctg cattttggat gttaggaaaa aatattccac aagtaaattg gccagcatgt
    16081 ggtgaaattg atattatgga acatgtaaat aatgaatcaa gcactcatgg tactattcac
    16141 tgggattata atggacatca atcttatgga actacatcac ctaatattga tgttactcaa
    16201 tatcatgttt attcagttga atgggataaa gatgcaataa aatggtttgt agatggaact
    16261 aaatatttag aagcaaatat atcaaacaat attaatggta ctgatgaatt ccataagcca
    16321 ttctttattc ttttcaattt agcagtaggt ggagaatggc ctaaaaatcc tgatggatca
    16381 actgcattcc cagctaaaat gtatgttgac tacgtacgtg tgtatcaagg aaacggtggg
    16441 tcgcaaacac aacctacaag ttcaaaatta ccaagtaata catggtatct atttaatcaa
    16501 tctgtaactg gagtaggagc ttcaagtcag gatatgcaaa ttggcaaggc tggtgttagt
    16561 ggatggcaac ctacaaaaaa tgtaaatgca ggctacaact tatggactac tccaacaatt
    16621 aatggaactt ataatgcagg taagtggaat tttaccctat ggacaaataa tccaggaact
    16681 tctaatatag cagttgatct ttataaggtt aataatgatg gaacaggtga aacattactt
    16741 ggctctcaaa ctgtagatgt atcaaaaact ggtggtggaa atcatccaac tgtatattca
    16801 tataatttag gtcaggtttc acttgctaac caaagattaa gagtaaaaat acataaggta
    16861 tctggagcag atgctgtaat gtgttataat acaaatgatt tttcaactaa attggtaact
    16921 ccataatata tagaaattat gttataaaaa ctaatttagt ttttataaca taaggctgtc
    16981 gagaaatcgg cagtctttat tctgtaaaaa atcatgtact ttattacatt aacttaaatg
    17041 tatttgaatg aataatttta tatgtgtatc tgcatataat aaaaatagag agtatataat
    17101 tttaataagg aaaaagatta tataatcttt atttggtgct taaattacaa aaatataata
    17161 aaatattgag aaaagttagt gggggataat atggaaagag tatttgatca attcaactat
    17221 ggtaacgtat tcataactgg cggagttaat aaaggaaaga catcaatttt agctactttg
    17281 atggagaact gtatagataa aggcgagaat atttatttta tagatgctga atatgaatta
    17341 tctaaggtat ttgacaaata tgataatgtt aaatcattgt ttgtatctag caatgtagta
    17401 aaggtgaaac agtttgtatc agatatgaat aatggtgata ctctaattat agatgcttat
    17461 ggaatgttgt cttctagtgt taaaagttat ataaaaaaat ttcttgctac aaataaatat
    17521 agagctataa tagcatcgaa gaatgctaat gatattagtg ttactcaatt tacaaatgtt
    17581 atagcattag gaactacaag gagtttttcg aagcatatag gggttgatac ttctacatta
    17641 gcaagtgatg aagtattgat taatggagac aaaataatta aatttaatta tagtgaattt
    17701 attggatata aagctggatt agtaatatca agaatgaaat aagaattatg tatagataaa
    17761 caacttagaa tttagactta ggcacacgaa ataaaataac aatctcaaaa tgtaaagatt
    17821 atttttcgtt aggcaaggaa taagatcggt cttatagcaa gtctattagg gagatctgct
    17881 catgagcata aaagttttac agctagcaag ttgttataaa ataatatgtt aattgattag
    17941 ttctttaata atttataaat cacactttgc ttttaatatt tatccgaaat tagaaataga
    18001 agacactctt ttgtagtgag ctgctgaatt gtctagcagt actacgcaaa agagtgtcta
    18061 ttattttgac tatttataca tattcgaata gattgaaaaa ttctgtgtga caaaatcaca
    18121 gataagtata agtttatgat ataaacttaa gaaaagaaat caagaatcta aaaaataaaa
    18181 atcctatgat ttctaaatgg gaatgattga ataaagtttg ttttttaaac aaaatatatt
    18241 aataagtcac aatcaaataa attattattt ataaatttta ataattatga ggagagataa
    18301 tatggctaaa aaagttatta ttgtaggtgg agttgcaggg ggagcatcaa ctgcagcaag
    18361 gcttagaaga ttagatgaaa atgcagaaat aatcatgata gaaaaaggtg aatatatatc
    18421 ttttgctaac tgtggtcttc catactatat aggaggaact attaacgaaa gagaaaaatt
    18481 gattgttcaa acagtagaag aaatgagcgc taagtttaat ttggacatac gaaacttaag
    18541 cgaagttata aggatagata aagataataa aaagataaaa attggaaata agaaaaatgg
    18601 agagatttat gaagaaggtt atgatgtatt agttttatca ccaggagcta atccattaaa
    18661 accaccaata ccagggattg aagaatgcga taatctgttt actcttagga atatacctga
    18721 tactgataaa atcaagtcat atgtagataa taaaaaaatt aaaaatgcag tcatagtagg
    18781 tggaggattt ataggtcttg aaatggctga aaatcttcat gaaagaggaa taaatattac
    18841 gttagtagaa gcaagcaacc aagttatggc agctcttgat atagaaatgg taagcataat
    18901 tcatgaacat ttaatagata aaaatataca actaatattg aatgatggag taaaatcttt
    18961 tgataataaa ggcaaaaaaa taatattaag tagtggaaaa gaaattgatg cggatatgat
    19021 aatattatca attggagtta agccagaaac agcgatagct aaggatgcta atattaagat
    19081 aaatgaaaaa tgtgctattg tagttgataa gaatatgaaa acttctgatc ctaatattta
    19141 tgcgttaggt gatgctgttg aaataatgga ttttgtaaat aaaaaaccta caatgattcc
    19201 attagcttgg cctgcaaatc gtcaaggtag aatagtagca gataatatat gtggaaaaaa
    19261 tgtagaatat aaaggatcac ttggctcatc agtagcaaag gtatttgatt atacagtagc
    19321 tactactggg aataatgaga aaacattaaa aagattgggg atagaatata aggctattca
    19381 tatacatcca gggtctcatg ctggatatta tccaggggct tttcctatag catttaaaat
    19441 gttatttgat cccaaaaatg gaacaatatt tggagctcaa ggtgttggga tggatggtgt
    19501 tgaaaagcgc atagatataa ttgcaacagc cattaaagga aatcttaatg tttttgattt
    19561 acaagatgtt gaggtttgtt atgcaccacc atataattca gcaaaagatc cagttaatat
    19621 gctaggatat tatgcttcga atattataga tggtatagta gatataattg aatgggatca
    19681 aatagataaa ttagataaga aaaattcaat aatattagat gttagagaag aatttgagtt
    19741 agcaacagga acatttgata attatatgca tattccactt ggagaattaa gaaataggtt
    19801 gaatgaaata ccaaaagata aagatatcta tgttacatgt caagtagggt taagaggata
    19861 tgttggctgt aggttattag aacagcatgg aattaaatgt actaacattg acggcggaat
    19921 aaagacatat ttttatgtaa agaatgcaga aaaaagcatc agagatcaac atgaaagaaa
    19981 taaagatata aaagaagagg tagcagtaat gagtttagaa gacttagata taacagaaat
    20041 aaacgctaag gtaactttaa atgcatgtgg acttcaatgt ccaggaccaa taagaaaggt
    20101 atttgaagaa ataagtaaaa tggaagatga agaaatttta gaagtgaaag cgagtgatcc
    20161 aggttttagt aaagatataa agtcatggtg tgaaaaaacg aacaatacct tattgaaatc
    20221 agaatttaat aaagatgaaa aagctttcgt agcttatata caaaaaggta ctaataaaaa
    20281 acaagaaagt tctacagctt taacagcaga aaagaatggt gcgactttag tagtatttag
    20341 tggagacttt gataaagcaa tagcatcatt tataatagca acaggagctg catccatggg
    20401 aaaagaagtt actatgttct tcacattttg gggccttaat atattaaagc aaaagaataa
    20461 acctaaagtt aataaggatt ctatggaaaa aatgtttgat attatgttac caggacatgc
    20521 agggaaatta ccactatctc aaatgaatat gatgggaatg ggaccaacaa tgataaaaca
    20581 aataatgaaa aagcataatg ttgatgattt agaaacatta ataacaaatg caattaagat
    20641 gggagttaag gtcgttgcat gttctatgag tatggactta atgggaataa agaaggaaga
    20701 atttattgat ggagttgaaa ttgggggagt tgcttcatat ttaggagcta ctgaagattc
    20761 agggttaaac ttatttattt gattgtgcct aagtcagtat gaggtgaatt ataaatcata
    20821 tctttgactt attattttct tttattatat aatttgataa atagaagcgg aggatagtta
    20881 tgaaaatatt acttatgaaa gttaaattaa gagcttcatg ggtacattca ttaaaagaaa
    20941 aaagaatgat tgtaaaaagc atagtacaga ggcttagaaa taaatttaat atatcagtat
    21001 gtgaagtaga atgtcaggat atgcatcaaa caatagttat aggaatcaca ggaatatgtg
    21061 gaagttcatc tcaaatggac tcaacaattg agaatataat aacatttata gaatgtaata
    21121 cagatgcgga gataatagat attcaggcgg aagaagatgt attataatta aataataaat
    21181 taaaatatag aggaagaaat tatacaaata tagttttttc ctctatttaa tatttctaga
    21241 ttctcaatta atattatttt taaattagta aaaattaact ttacatctcg ttttaggcac
    21301 tagaaagaaa ataacaggcc aaagatacca agtacatttt gtgtcagaca aggaagagat
    21361 gttagcttat agtggattat tagctaatat tactgacgca gtatgcacaa aatagactat
    21421 catactgact tgttattttt ttgatagcgc tttattgtat atggattaat aaattgatat
    21481 tattaatata caacaatgta agtataaatg gtagaacgca cttaaaagta tgatactacc
    21541 taaaaggaga gttagaaatg aaatgcatgt gtaaaattga caatccgcta gaaactccat
    21601 ttggatatac aatatcaatg ataggaggta aatggaattt aataattcta catcaactta
    21661 agcgtaattc tgtaatgaga tatagtgagt taaaaagaac tttaacagga attactcaca
    21721 aaatgcttag tcaaaaatta aaggagttag aaggtaataa actaataatt agaaaagaat
    21781 atcctcaagt accacctaaa gtagaatatt cattatcaga acgaggatta tcgctttcaa
    21841 aaattatgca ggatatttgt gaatggggtc atgctcacag caatgattaa tttacatata
    21901 tctatttatg gataatatcc ttaaaacttt gcgaaaatat ttttataaaa aatatgttaa
    21961 tattttccta tcaaaatata taaatatttg taggaaacat caatgagaaa atgacttttt
    22021 aaggaattta aatttagaag atgttggtta atggaggatt atattttggc ttagtgtgag
    22081 agtaacacag acagtaataa caataaacca cccgtttttt tacgggtggt tcttattgtt
    22141 gaattatgat taaattctac attatattac taattgtcaa gttctaagca atcgtaagca
    22201 taagaagcgc taaggtaagc actaatatca cttgaaccac taacaggttt aatagttatt
    22261 gtgtttgatc cagctacaaa gtaagatgat ggaatgttcc aagcaagtgt tgcattgttt
    22321 cccctgtaag tgccaacagt tagtgtgcgt tgaccgggtt ctattggagc acttagatta
    22381 ggcaaagcat gtccattaat agtaacacta ggtcttccat tattgtaagc agtagtaata
    22441 ccaattttaa gggtgtgacc tgcagctgct tggccatgag taaggttaaa agttactgtt
    22501 gtaggactgt tagctccacg gaattgtgct gctggaaatt tgttatctgc acttcctact
    22561 gaaaaagttg ttggtcccca actagcatta cgtttatcag atggatgacg gtattgaata
    22621 tttgatccat ttaaaaactc taaaggtgta ccatcccagt taccgatacg ccatatagtt
    22681 ggtgttttgc ttggatcagc ggtaattgta cgtgtaggga tagttgttgt acctctagca
    22741 gttactgtta cgctttctgt ataaacacct aattctcctt tatatacagt catagtatat
    22801 ttaccagctt tcatacctga acatgttgct gcgccagttg aagaagcttt agcccagtac
    22861 tgtgcagttg aattagcaaa tccaatagta tatgtatagc gtgtatccat tccagacaat
    22921 ccatttaaag ttactttacc acgattagaa tctgcaacat aaccttttaa tcctaaggta
    22981 gccatccatt tataatcagg taagcttggt gttgatccgt tagtaaaaca taaagcatat
    23041 ggtccgaata atccgctgcg gaagttttct gtttttgcat gtgtagaatt catatagtta
    23101 gtgatttctg tattcatatt atctggatag gcagtttgaa attgaatatc acgttggaat
    23161 gatccaccag aactggtttc acgattacca taagccataa aaacacctac attattacca
    23221 gttgcacctt taatagttag atctttagct tgatcatttc catagtactt agaagcagta
    23281 tgtccatcag aaaaaccata tacatcagta ctttcaatag ctccattatt gcctctaatg
    23341 tctgagtatg taggaacatt ttttaaaaca ttcatatctc ccctaaaaac ataacgtaat
    23401 tcatttactg aaggttcagc agttatatat gttgacatat aaattgtgtt atcaccatat
    23461 tttgaggcat aatattgtgt aagtgtattg gttgaacaag ttattaaaac ttgtgaacca
    23521 gacgaaaatg ttgaccaagt gacatgagct gatcctaaac ctgatgaaat ttgtgatgct
    23581 ttattcttag cattaagttc agtaccatta agtttacatg atgtcatatc accattagct
    23641 ttgttaattg tgtaaactag acctgatcca gtatctacaa caattgtgga gccattatct
    23701 tttacgttaa gtgaagcagc ataagcatta attccttcag taaaagtggt aacaataata
    23761 atagctatcg ctagcataac actaattgcc gtttttagcg aagtgttgtg tattttaatt
    23821 ttcat
//
