LOCUS       NC_022571.1            24973 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_022571.1 Clostridium saccharobutylicum DSM 13864, complete
            sequence.
ACCESSION   NC_022571
VERSION     NC_022571.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:58:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 570243
            Orig. end    :: 595216
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24973
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[580243:585216]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..24973
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24973
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Rnf_complex"
                     /region_number="3"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             84..1379
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_473"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.9e-08, bitscore:
                     32.3, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSIENWFCENDDKIKQTERFIFENPELSLEERQSSQCLAKFMEE
                     QGFSVEWNIGGLETAFVATWGQGEPVLGFLAEYDALPGLGQKPVEERCEIEGCGHGCGH
                     SLLGVGAAAAAAALKSELEFSGKLGTIKLFGCPAEEIMYGKIVMAKQGCFDGLSAAITW
                     HPSDSNRVGEDIYQAMDSKKFKFFGTTSHASGSPHLGRSALDAAELMNVGVNYLREHVT
                     DDVRIHYTYLDGGEKPNIVPDFAQTSYYIRGKNREHVDDASARIERIAQGAALMTDTRY
                     ESELVASCMETKLNFTLLNAFYKAMSGIEVPTYTQEEIQFAESISKAANLKNQGKYFDG
                     LHKFENREIDIFISTDVSNVSHIVPTITLNAATACKGTPLHHWAFTAQVGSSIGYKGMI
                     YVAKSMALGGMMLIDNPEILLKAMDEHKNSSI"
     CDS             1411..2103
                     /locus_tag="ctg1_474"
                     /transl_table=11
                     /translation="MKELDNIQCTIEHHATLFALFAKYIIEGLDEKGKDIIYTAVENYG
                     QERGKRMANRAVANGDDLDFINSQAYGEWVPEEGQMEFGVLKTQPELISNVTKCEWCRV
                     WKKYNLLDYGKYYCINIDSAVFNGFNEKFHMKATSNLSFGADHCEFHWGNSMSEEDSKR
                     LVKKKAELGTSCTRDFNFHTAHLLHSISETLEKELGEDGKLIINQVLEKYIELFGEEYL
                     TVLDGKYE"
     CDS             2120..2929
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) P5CR_dimer"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_475"
                     /sec_met_domain="F420_oxidored (E-value: 3.1e-20, bitscore:
                     70.6, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="P5CR_dimer (E-value: 5.8e-28, bitscore:
                     95.3, seeds: 951, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNNKITFIGGGNMAEGIIKGIVSNEVFQPKNITVFDILNERRKY
                     LKDIYGITEAEDTSSAVKDADIVLIAVRPQDIVKVAQNIKNDLSKSAIIISICAGIKME
                     KMEELFGSEHKFVRVMPNTMIEVQHGYSAASVNDKVEESDKEIIKSLLNALGQTMFIDE
                     NMFNAFTAYSCAGPAYVMYFIAALVDSGVQSGFSRKDAISIALENLMASALTIQKTGKH
                     PYQITDTMTSPAGITIDGLHVLSESGFHGTVMSSIRKALERTNELEK"
     CDS             3224..4171
                     /locus_tag="ctg1_476"
                     /transl_table=11
                     /translation="MDKTKFYTNRKNIIILAILCCILWGSAYPAIKAGYSLFNIGENAI
                     GSKLVFAGYRFAIAGILVILLELATKKNIFEFSKKQFGQIFILGSTQTALQYIFFYVGL
                     SYTTGVRGSIINGTGTFASIILAHFIYKNDKLNFNKILGCIIGFVGVVIVNLNGQSLGG
                     SSFTFKGEGFIMIAAFIFSASSIYGKKITQILEPPIVTGFQLFIGGIILIGLGFCFGGS
                     LSRFTMKSTSLLIYMALLSSVSFAIWTQLLKYNKVGIISVFNFLVPVFGTLLSAIFLGE
                     NIFDIKILISLILVCYGIFLVYRVKKENTAPVAE"
     CDS             complement(4555..4968)
                     /locus_tag="ctg1_477"
                     /transl_table=11
                     /translation="MWVVCALLSALFAALTSILAKIGIEDVNSNLATAIRTAVVLFMAW
                     GIVFLTGTQNQISSIRSKSWIFLILSGLATGLSWLFYYKALQIGQASKVVPIDKFSVVI
                     SMILAFIVLKETMTIKTILGGIFITIGTFIMIL"
     CDS             complement(5273..6652)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_478"
                     /sec_met_domain="Radical_SAM (E-value: 8.3e-15, bitscore:
                     53.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYLGNRARKTIMKSVCTTLERNPEKNIPRLFKMLKLLAKDE
                     DSNKAIRNIETYYSDNPSIKQLIDSILIETNPKFLKKFFVNFIANAIWIGGKKRSELLE
                     NEDIKVPFTLLISPSMRCNLHCTGCYAAKYDKLNGLTYEEVDRIIGEARDLGVHYIIVL
                     GGEPFFVDFMYDIYKKYDDILFTPFTNGTLFNNDIADKLVSLGNVMPMFSLEGFEKETD
                     ARRGSGTFNKVMEGMDLLKSRGIPFGVSSATSTNNLKTVTSDEFIDMLVKKGSRMNWYF
                     MYMPVGESPNIDNMLKPAERIELGRLTKKIRSTKPYFTIDFFNDAPYVGGCIAGKYYCH
                     INSNGDVEPCVFAHIACDNIKDKNLIDIFKSEFFKGLRHRQPYNKNMLRPCMMIDNTNV
                     IREVSEKFNAHPTDESAEAMLHDKDFQAKLDKLSSDFKPYADEAWEKDFKSKGNDSFAK
                     G"
     CDS             6849..7454
                     /locus_tag="ctg1_479"
                     /transl_table=11
                     /translation="MKIEDIKNKIKDNKPYINGWERMKRSSIIIPLVKINNEICILFEV
                     RAKKLSSQPGDICFPGGKIDGNEAPKEAAIREVFEELGIKDVDIINELDTVVRYDNIII
                     HPYVGVIQNINEIDMNESEVDHTFYVPVNYFLNQEPLEIENKLNVERPEDFPYDLIVNK
                     HNYKFKNGSYRVLFYKYEDYNIWGITAQILNNFLEKLR"
     CDS             7688..8152
                     /locus_tag="ctg1_480"
                     /transl_table=11
                     /translation="MRNIFYYNTMIGELGIEENGLAITKVFLVDKDIEKGPSEKNETEL
                     LKEAIKQLNEYFDGKRKEFNLPLAPKGTEFQKKVWNTLKEIPFGETRSYGEIAKLIGNE
                     KASRAVGMANNKNPIMIIIPCHRVIGANGKLVGYAGGIDIKEKLLNLEKN"
     CDS             8383..8826
                     /locus_tag="ctg1_481"
                     /transl_table=11
                     /translation="MDKFETIKNNISENEPTRNNLLKAVTNFKLSTKALQKITGLDPEW
                     LNSYLNKRASVHDLSYQSMAELSNLSFMLSDAITFVDNDDRIKGIIDILKEEFYISYET
                     IALYAKIDVIDVEKFIEDTKSIGFEKKYKIATISSLLLYLSKK"
     CDS             9445..9855
                     /locus_tag="ctg1_482"
                     /transl_table=11
                     /translation="MKTEQGLVIEVSDNVAKIKVGRHNDCKNCGACPGNDSIVITATNK
                     IGAKPGQRVAFEVKESNFLMATFVVFVLPIIALFIGVLLGGVVSKYIGSNIRISQIIGG
                     IIMFVLSLIFVKSFDKTASANNKSQPVIVRIL"
     CDS             10001..11320
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_483"
                     /sec_met_domain="Fer4_10 (E-value: 9.4e-12, bitscore: 42.9,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4e-05, bitscore: 21.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.6e-14, bitscore: 50.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7.9e-54, bitscore:
                     179.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 9.2e-36, bitscore: 119.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.2e-05, bitscore: 20.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKSFLGGIHPNDSKKYTFDKAIESPSLPDEVVIPVSQHIGAPCT
                     PIVKVGDSVKKGQVIANSDAFMHSPIHASISGKVTKIADMPHASKGSCLSIVIKNDGLD
                     EWIEGIPLNREWDKLNAEEIRNIIKDAGIVGMGGATFPTHIKLNPSKDKKIDVCIVNAA
                     ECEPYLTADYRMMLEYADRIVTGVKIIMKVLGVTKVFIGIEDNKMDAVKVMKDAFKDTS
                     VEVVPLPTKYPQGAEKMLIKVLTGREVPTGGLPMDVGVVVQNIGTTVAISDAVVNGIPL
                     IQRITTVSGDAIKEPKNLLLRIGTSFKYAINYCGGFSKDPEKIIMGGPMMGFAQSTLDV
                     PVIKGVSGILALSSDVVNSGEESPCIRCGRCVKACPMGLIPSMLSILGQRHKYKEAKEN
                     YNLFNCIECGSCVYSCPAKRNIVQYIKYSKAQNLAHAANK"
     CDS             11336..12373
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_484"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.6e-111,
                     bitscore: 368.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEVKVQEGSLQEIKAKEIGIEENQFTVSASPHIRCDESISKIM
                     WNVNLALAPAAIFSICYFGFPALINMVTGAVSAVLFEYLVEKFRKKKITAFDGSAFLTG
                     LLLAMSVSPSLPPYMMIVGSFIAIVIAKHSMGGLGFNIFNPAHIGRAALMVSWPVAMTS
                     WTKMTTSVDVVSSATPLNILKQQGYSKLVETFGSQAAMYKAMFLGTRNGCIGETCTILL
                     VLGGIYLIYRGYVNWQIPVCMIATVGILTWVFAPTGLFTGDPLFNMMAGGLILGAFFMA
                     TDMVTIPITIKGQIIFAVGAGAITSLIRLVGGYPEGVCYSILLMNAVTPLIDRFVKPKE
                     FGARG"
     CDS             12378..12941
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_485"
                     /sec_met_domain="FMN_bind (E-value: 8.4e-21, bitscore:
                     72.4, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGAHVNKEYSIFQIAINLIITCLVSGLIIGLVYYFTAPIAAEKK
                     EVSKQESMRSLVSDADNFKAVPDKDQWFTAEKDGKIIAYVVPGESKGYGGEIKMLVAVK
                     PDGEVIDYSITTSNETPGLGDNASKQPFKDEFKGKKEANLTVTKDASDKDDIQAMTGAT
                     ISSRAVTLAVKNAVHEVTDFTGGK"
     CDS             12944..13570
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_486"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-58, bitscore:
                     195.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKWKIFSKGLYDENPIFMLCLSLCPALAVTSSVINGLTMGLCV
                     TFVITCNNVVVSLTRKFVNPKVRVPVYITFIATIVTVVELVLQAISPTLYSALGIYLDL
                     VVVFAIILARAEVFASKNKVFPSFLDGFGMGCGFTLAMLSISIIREFFGSGSICGFRIL
                     GTWYNAPLIMILPAGAFILIGYMIGAIKLHNANREAKKVEEGSEA"
     CDS             13570..14145
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_487"
                     /sec_met_domain="Rnf-Nqr (E-value: 8.1e-51, bitscore:
                     170.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYFTLFIGALLVNNFVLTKFLGLCIFFGVSKSLNASIGMGMAV
                     TSVITLSSMLAWIVYHFVLLPFNLTFLTTIVFVILIASFVQLLELIIKKQAPTLYRMWG
                     IYLLLIATNCIVLSVPLLNVQSNYSFVKSIVFSIGSGMGFALALILMASLREKLVYADV
                     PKPLEGTGIAFILAGMLALAFLGFSGMI"
     CDS             14164..14973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_488"
                     /sec_met_domain="Fer4_9 (E-value: 4.8e-09, bitscore: 34.3,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.1e-08, bitscore: 31.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.3e-06, bitscore: 24.9,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.4e-11, bitscore: 41.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00024, bitscore: 19.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTVIMVLAVMVGIGIVFGFILAIANKKFSVEVNPLIHEVEDVLP
                     KGQCGACGYAGCAGYAEAVVLNKEVPPNLCVPGKDAVAKLVAEITGKSAEKVEPRIAHI
                     KCKGAIGKAKLSYNYKGIEDCAAATLLQGGPKGCKHGCVGFGTCVNSCPFGALSMGEDG
                     LPKVDAKKCTGCGTCETACPKNVIEVMPVNSIVKVNCNSKDKGAIARKLCSAETCLGCG
                     ICAKNCTYGAIKIENNLAVVDSKICVEKCKEPTCLAKCPTSAIKIAN"
     CDS             15335..16384
                     /locus_tag="ctg1_489"
                     /transl_table=11
                     /translation="MKKNICAILVFISIVLNFTSCDSSRNKYYEKSNIVMDTVVTLSAY
                     GENSKEAVEESFKKLDEINEMASTNIDTSDIYKINNSSGESYVQVHPEIMKMIETSIKY
                     SKLSDGAFDITLGPIIDLWGIGTDNERVPSDEEIKAKLPLVGCDKISINEEESSVMLQK
                     KGMALDLGGIAKGFAADEVLKIYKKYNIENGLINLGSSSIYAVGKNKDNNKWSVGIKHP
                     RSEDSKNYLGIIKLSNEALSTSGDYERYFIKDNKRYHHIINPKTGYPADNGVMSDTMVI
                     DNDDEDKNMLADLLTTTVFILGPEKGLNLIKTLPNVSCEITTSDYKIYTSDDFKDRITD
                     LNKEFEFAN"
     CDS             16531..16911
                     /locus_tag="ctg1_490"
                     /transl_table=11
                     /translation="MFKKWDIIIIIFLICLSFIPEIIFGVAMGKNYNGTYAEITLDGKL
                     YKKILLSEHRGKEEFDIKTKYGYNEVEINDQSIGILDADCPDKICVHSGFISEPGQISV
                     CLPHKLMIEIKSSNNEKNLDVS"
     CDS             17004..17534
                     /locus_tag="ctg1_491"
                     /transl_table=11
                     /translation="MKKTFRIVFIGLLVSQALALYTIESMIPVPFIAPGAKLGLTNLIT
                     VIALYILNNKKDVFLIILLRLLLSTIFNGSLSTFMYGAAGAILSYYVMIFVKKFGKDRV
                     SIVGVSCSGAVFHNIGQLVVASAIVQNIAVMLYLPILSIAGIGTGIFIGVTANFVVKHL
                     SKLPYFKSLNLDL"
     CDS             complement(17899..18546)
                     /locus_tag="ctg1_492"
                     /transl_table=11
                     /translation="MINLCIINGSPRKGKGTSSYLINELTKLLSTNVKSKEYYISNLVN
                     NENSLNELLLYDKVIFISPLYADCFPSTMLNFLATFEDFLKDKNTPNIDMYGLVNCGFL
                     EGIQNKIALDILKNYSKRINFNWRFGLGIGGGEFLKGSKNIPLNSRMKKPVYNAFLTLK
                     NDIEDNSNNSINNIFTNAKMSKLIFKLAGNHGWKSMAKKNNLKVKDLYKQIY"
     CDS             complement(18561..19070)
                     /locus_tag="ctg1_493"
                     /transl_table=11
                     /translation="MLLIHDLNVDDSKELTSVLPPNSRVLSKEIDNINGCLGCFNCWLK
                     TPGRCIIEDSYTEMPKYILEGDTFVILTEIKYGCYTSYVKNVIDRSIGILLPFFQTVNG
                     ELHHLPRYKKDLKFIVIGYNKNITFDEEETFKDLVRRNAINLCIPDYEVYIIKDISESK
                     KILKNL"
     CDS             19505..20098
                     /locus_tag="ctg1_494"
                     /transl_table=11
                     /translation="MQVDKYHHGDLKESLIKMGLKLFNEEGAEKFSIRKVAAMCNVSHS
                     APYKHFKNKEELINAISEYVFYNFKNSLNEIVEKYKDNPGERIIQLGKKYVAFMVENPD
                     YLKFAFLTNSEYKITIEKNTLKSEECGTFKVFENCAFEFLQSVNVKEEKYAQDIIAMWS
                     MVHGLATMLSNKTFTYKGDYLSLVENILRNNLRF"
     CDS             20154..20543
                     /locus_tag="ctg1_495"
                     /transl_table=11
                     /translation="MYNMKEEYKIGLDHIDKQHEKLFELANKAYMLLKDEFAVDKYDKI
                     VEIINELKEYTIFHFKSEEEYMESINYKGLFSQKLQHEKFINVLQELDFKQIDENQDES
                     LIKVLDFLNDWLSDHILISDKFIGK"
     CDS             21009..21593
                     /locus_tag="ctg1_496"
                     /transl_table=11
                     /translation="MNEKTSKLVKISLLSAIALILRYIEFPVLPLFPWLQMDLSDVPAM
                     LGTFGFGPIVGIIIELLKNVLILGIKGTSTAFVGEVANFLFGVALLVPAGLVYHKKKSK
                     KTAIIGMILGGIFMEVVAIIVNAYFLLPAYGMNMDSAQLMQYITLGLLPFNGIKSVIVS
                     VVTYVLYKKISVSIFKVEPNFGGSKNSAKTM"
     CDS             complement(21822..22265)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_497"
                     /sec_met_domain="Acetyltransf_10 (E-value: 2.1e-20,
                     bitscore: 70.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVTVDLMEEEDIDGVLDISSLSFSLPWSKESYIQELNNPIAHYF
                     VARCDDIVVGFVGTWIILDESHITNIAVHPNYRTQGIASKLLDELLTYCKSKGCIAYTL
                     EVRASNENAQKLYLKHGFKKDGVRKGYYEDNKEDAILMWLRES"
     CDS             complement(22249..22965)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_498"
                     /sec_met_domain="Peptidase_M22 (E-value: 9.1e-26, bitscore:
                     89.1, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVLAVDSSSKVATVALMKDDKLLGEITLNDKKEHSVILMTIIED
                     LLKFNNLTIDDIDGYVVSKGPGSFTGLRIGMATVKGLSFGSGKPYVSLSSLDALAFSVA
                     NFDGLICPIMDALRNSVYTSLYKSCNGSLEKLMDYSALDMDELVEIIKSKGEKVIFIGD
                     GLDKYKDYLIENCPNCYFPPNHLNLVRASSLGEIGSKLLRDGQFDDPNSTPFYLKKPQA
                     EREYEQRMQLRNECNC"
     CDS             complement(22962..23423)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TsaE"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_499"
                     /sec_met_domain="TsaE (E-value: 7.1e-39, bitscore: 130.7,
                     seeds: 801, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFEINSVAETTQLGIKLGKLLNAGDIICLTGDLGTGKTHITKGI
                     AKGLGIDETITSPTFTIVNEYDSGRLKLNHFDVYRVSDPDEVYAIGFDDYIFSDAVSVI
                     EWANYIEEILPKDLLHIYIEKDLAKGEDYRKIILTPYGERYNYIKELTI"
     CDS             24036..24938
                     /locus_tag="ctg1_500"
                     /transl_table=11
                     /translation="LKKITFAMVLITIVLSLGMSVFSSPLLANTENKSNAEMRDKYLNI
                     MTVNKPQYDMVKKIIKDKHNVQYMFTDEKEISEFKYNASVLENVSNMDLFIYSGATFEP
                     WANSFISELTKGNLGIINLSRGVRLLNYDEGATKENPYYFEGIDEYKIALCNVKAAIED
                     RDPKNRDFYEKNYNIAIKEFNDKLKSYDDKIKSLSDYTFITLNHDFDYLTKSLNLNIKE
                     LNNHELGEFIKSNNLDPKKVIVIVDGEQDPKINLSGYNTIKLWKYYGDWSFDDLILYNI
                     DELAKWAKPADKSSTGSVA"
ORIGIN
        1 tactttcttg catgatgaaa aataatcttg ggattttgga attgttattt tctttcatgt
       61 gcctaaataa ggagcataaa gatatgaata gtattgaaaa ttggttttgt gaaaatgatg
      121 acaagataaa acaaacagaa agatttattt ttgaaaatcc tgaattatca ttagaggaaa
      181 gacaatcatc acaatgttta gcaaaattca tggaagaaca aggtttttca gttgaatgga
      241 atataggtgg gttagaaaca gcctttgtag caacatgggg acaaggagag cctgtattag
      301 gatttttagc agaatatgat gctttgcctg gattaggtca gaagccagta gaggaacgtt
      361 gtgaaattga aggatgtgga catggctgcg gtcatagctt acttggtgtt ggtgcggcgg
      421 cagcagcagc agctcttaag agtgaattgg agttcagtgg taagctagga acaataaagt
      481 tattcggttg cccagcagaa gaaattatgt atgggaaaat tgtaatggca aaacaaggtt
      541 gttttgatgg attaagtgca gcaattacat ggcatccatc cgattcaaat cgtgttggag
      601 aagatattta tcaagctatg gattctaaaa aatttaaatt ttttggaaca acatctcatg
      661 catctggaag tccacactta ggtaggagtg cacttgatgc agcggaatta atgaatgtag
      721 gagtaaatta tttacgagaa catgtaacag acgatgttcg tatacattat acgtatttag
      781 atggtggaga aaaacctaat atagtccctg attttgcaca aacttcatat tatattcgtg
      841 gaaaaaaccg tgaacatgtt gatgatgcat cagctcgtat agagcgtata gcacaaggtg
      901 cggcattaat gacggacaca agatatgaaa gcgaattagt ggctagctgc atggaaacta
      961 aattgaattt tacgttactt aatgcatttt ataaagcaat gagtggtatt gaagtaccaa
     1021 cttatacaca agaggaaata caatttgcag aatcgattag taaagcagca aatttaaaaa
     1081 atcaaggtaa atactttgat ggattacata aatttgagaa tagagaaata gacatattta
     1141 tttctacaga tgtatctaat gtaagtcata ttgtaccaac tattacttta aatgcagcta
     1201 ctgcatgtaa ggggactcct ctacatcact gggcatttac agcgcaagtt ggatcatcca
     1261 ttggatataa aggaatgatt tatgtagcaa aatctatggc tctaggtgga atgatgttga
     1321 ttgataatcc agaaatatta ttgaaagcta tggatgaaca taaaaattcg tctatataaa
     1381 taaatattga gaaaggtgtg aggtataaaa atgaaagagt tagataacat tcagtgcaca
     1441 attgaacatc atgcaacatt atttgcactt tttgcaaaat acattataga aggtttagat
     1501 gaaaaaggta aagatataat ttatactgca gttgaaaatt atggacagga acgcggaaag
     1561 agaatggcca atagagcagt tgctaatgga gatgatttgg attttataaa tagtcaagct
     1621 tatggtgaat gggttccaga agaagggcaa atggaatttg gagttctaaa aacgcaacca
     1681 gaacttatta gtaatgttac aaaatgtgaa tggtgtaggg tgtggaagaa atataatctt
     1741 ttagattacg gaaagtatta ctgcattaat atagattcag ctgtttttaa tggttttaat
     1801 gaaaaatttc atatgaaagc aactagtaat ctaagttttg gagcagatca ttgtgaattt
     1861 cattggggaa attctatgag tgaagaagat tctaagagac ttgtcaaaaa gaaagctgaa
     1921 ttaggtacta gctgtactag agattttaat ttccatactg cacatctttt acattcaata
     1981 agtgaaacat tagaaaaaga gcttggagaa gatggaaaat taattattaa tcaagtacta
     2041 gagaaatata tagaattatt tggagaagag tatttaactg tattagatgg aaagtatgaa
     2101 taaagaggag gaattatata tgttaaataa taagattaca tttattggcg gcggtaatat
     2161 ggcagaaggg attatcaaag gaattgtatc taatgaagtg tttcagccta aaaatattac
     2221 agtttttgat atattaaatg aaagaagaaa gtatcttaaa gatatatatg gaattacgga
     2281 ggcagaagat acctcatctg cagtgaaaga tgcagatata gttttaattg cagtacgtcc
     2341 acaagatatt gtgaaagtag cacaaaatat aaagaatgat ttatcaaaat cagcaattat
     2401 tatttctata tgtgctggaa ttaaaatgga gaaaatggaa gaactatttg gaagtgagca
     2461 taaatttgtt cgtgttatgc caaacacaat gattgaggta caacatggat atagcgctgc
     2521 aagtgtaaat gataaagtag aagaaagtga taaagaaatt attaaatcac ttttaaatgc
     2581 attaggacaa acaatgttta tagatgaaaa tatgtttaat gcatttactg cgtatagctg
     2641 tgcaggtcct gcatatgtta tgtattttat tgcagcatta gtggattcag gagtgcaatc
     2701 aggattttca cgtaaagatg caatatcaat tgcattagaa aatttaatgg cttctgcatt
     2761 aactattcaa aagacaggaa aacatccata tcaaattaca gatacaatga cttcaccagc
     2821 tggtatcaca attgatggat tacatgtatt aagtgaatca ggtttccatg gaactgttat
     2881 gtctagtata agaaaagctc tagaaagaac aaatgaatta gaaaaataaa aatgatagca
     2941 gtagtaagta tgaaaagata atatgaaaag ccttaagaat gtatttgttc ttaaggcttt
     3001 tttatcttaa tatgtgtaat aaaaatataa ttgttcattt caattaatat gatatactta
     3061 aaatacagat gatttctaat tgcactagca attgaggcat gtaaaagaag ctgtaagaaa
     3121 tggaaaatga aaaataggct tgacagatgg actagctgtt tttgaatata tctaatatta
     3181 aacttactag tgtattttaa tttaagagag aagaattaaa gatatggata aaactaaatt
     3241 ttatactaat agaaaaaata ttattattct agcaatacta tgctgtattt tatgggggag
     3301 tgcataccct gcaataaaag caggatattc attatttaac ataggagaaa atgcaatagg
     3361 atctaaattg gtttttgcgg gatatagatt tgcaatcgct ggaattctag taattttatt
     3421 agaattagct acaaagaaaa atatatttga attttctaaa aaacaatttg gacaaatatt
     3481 tattttaggt tcaacacaaa ctgcacttca gtacatattt ttttatgtag gtttatcata
     3541 tacaactggg gtaagaggtt caataatcaa tggaacagga actttcgcaa gcataatatt
     3601 agcacatttt atttacaaaa atgataaact taattttaat aagatattgg gatgtattat
     3661 aggatttgta ggtgtggtaa ttgttaattt aaatggacaa tcgttaggag ggagctcttt
     3721 tacattcaaa ggagaaggat ttataatgat cgcagcattt atattttcag cttcatcaat
     3781 atatggtaaa aaaataactc aaatcttaga accaccaata gttactggat ttcaattatt
     3841 tataggcggc ataattctga taggtttagg tttttgtttt ggtggtagtt tgagtagatt
     3901 tacaatgaaa tctacatcgc ttttaatata tatggcatta ttatcttcag tatcatttgc
     3961 tatatggaca cagctattaa aatataataa agttggaatt atatcagtat ttaatttttt
     4021 agttcctgta tttggaacat tgttatcagc aatattctta ggagaaaata tatttgatat
     4081 taaaatttta atatctttaa tacttgtatg ctatggaata ttcttagtct atagagttaa
     4141 aaaagaaaat acagcaccag tagctgaata ataatgtgca ataaaataaa cacttttagc
     4201 tttagggtta tgtggtaact taccgaaatc acatatatat ttgtttcatc ggacttatga
     4261 aattttagtt ggaagattct aaatgggagc ttgcaaccat tgctgcatgt tccaaatatc
     4321 cattttgaca agcagcaaat ggaacaagca cccattaaga atcttcaata gctcaatttt
     4381 aaatgcctct tccacaaata tgtatatgat ttatagtttt agaaaattta ttcacattag
     4441 atataaaagt tttgtggata attaaaaaat aatgttgata gtttaaagag ttaaattatc
     4501 aacattattt tttaatcttt aggttgagat aatattatta agttatgttt gcatctataa
     4561 tatcattatg aaagttccta ttgttataaa aataccacct aatatagttt ttattgtcat
     4621 ggtttctttt aatactataa aagcaagaat catacttatt actacactaa atttatcaat
     4681 gggtacaact tttgacgctt gaccaatttg taacgcctta taataaaata gccaagaaag
     4741 tcctgtagcc aaaccagaga gaattaagaa tatccaactt ttagatcgga tacttgagat
     4801 ttgattctga gtacctgtta aaaaaactat tccccaagcc atgaaaagaa ctacagcagt
     4861 acgtattgct gtagctaaat tagaattaac gtcttcaatt cctattttag ctaatattga
     4921 ggttaaagct gcaaaaagtg cagacaataa tgcacatact acccacatct taattccccc
     4981 tttaactttt tggtgtatat acaatttaag ttcacctcga atataaaata tttagttaca
     5041 tgtctacatg gaattataga taagtagatt gtgaattagg cttatgtgac gatttgttga
     5101 ttgtgtaatg ttctttaatc acgctcacct tatatagatg aacaaattac taaactagat
     5161 ttatgagttg aaatatattc tgaaatagaa agaaatggtg ctctgtagta actgaaacaa
     5221 cggagtacca tttctttcgg taaattacta cataagttta aattccatac ttttatcctt
     5281 ttgcaaatga atcattgccc tttgatttga aatctttttc ccaagcttca tctgcataag
     5341 gtttaaaatc tgaagataat ttatctagtt ttgcttgaaa atctttatca tgcaacatag
     5401 cttcagcact ttcatcagtt ggatgagcat tgaatttttc acttacttct ctgattacat
     5461 ttgtattatc aatcatcatg caaggtctta acatattttt gttgtatggt tgtctatgcc
     5521 taagaccctt aaaaaattca cttttaaaaa tatcaattaa atttttatct ttaatattat
     5581 cacatgcaat atgagcaaaa acacaaggtt caacatcacc atttgaattt atatgacagt
     5641 aatatttgcc agcaatgcaa ccaccaacat atggagcatc attaaaaaag tcaattgtaa
     5701 aatatggttt agttgatctg atttttttag ttagcctgcc gagttctatt cgctcagctg
     5761 gctttaacat gttatcaatg ttaggagatt ctcctacagg catgtacata aagtaccaat
     5821 tcattctaga gccttttttt acaagcatgt caataaattc atctgaagtt acagttttga
     5881 ggttattagt tgaagttgct gaggatacac caaatggaat gcctcgtgat tttaataaat
     5941 ccattccttc cataacctta ttgaatgtac cactgccacg ccttgcatca gtttcttttt
     6001 caaaaccttc aagagaaaac attggcataa cattacctaa ggaaactaat ttatcggcta
     6061 tatcattgtt gaaaagcgta ccatttgtaa aaggagtaaa gaggatatca tcatattttt
     6121 tatagatatc atacatgaaa tcaacaaaga atggttcacc gccaagtaca ataatataat
     6181 gtactccaag atccctagct tcgcctatta ttctatcaac ttcttcatat gtaagtccgt
     6241 ttaatttatc atattttgca gcatagcatc cagtacaatg taagttgcat ctcattgaag
     6301 gactaataag aagcgtaaat ggaactttta tgtcttcatt ttcaagaagt tccgatcttt
     6361 ttttaccgcc aatccatatt gcatttgcta taaaattgac aaaaaatttt tttagaaatt
     6421 taggattagt ttcaattaag atagaatcaa taagttgttt aatagatgga ttgtcgctat
     6481 aatatgtttc tatgtttctt atagctttat tactatcttc atctttagca agaagtttta
     6541 acattttaaa aagtcttgga atattttttt caggatttct ttcaagggtt gtgcatacac
     6601 tcttcataat tgtttttcta gctctatttc caagatattc atgtaaattc ataaaatcac
     6661 cttcataact tttagattta aaatgtttag tatatattta tgtgacgaaa aggcaaaata
     6721 tattaaaatc tgtaaagttt ttaaaaatca atttttaata gaaaagaaat agagttaaga
     6781 ttatcttaat atttgtaatt tgatataata tttatataaa atagttagca aaggggagat
     6841 tatagtatat gaagatagaa gatataaaga ataaaataaa agacaataaa ccttatatta
     6901 atggttggga aagaatgaag aggtcatcta taattattcc tttagtaaaa ataaataatg
     6961 agatatgtat attatttgaa gtaagagcca aaaaattaag cagtcaacca ggggatatat
     7021 gttttccagg tggaaagata gatggtaatg aagcgcctaa agaagcagca ataagagaag
     7081 tgtttgaaga gctaggtatt aaagatgttg atataataaa tgaattggat actgtagtta
     7141 gatatgataa tattataatt catccttatg tgggagtaat tcaaaatatt aatgaaattg
     7201 atatgaatga aagtgaagta gatcatacat tttatgttcc agtaaattat tttctaaatc
     7261 aagaaccttt agaaatagaa aataaactaa atgttgaaag gcctgaagat tttccttatg
     7321 atttaattgt taataagcac aactataaat ttaaaaatgg tagttataga gttttatttt
     7381 acaaatatga agactacaat atatggggga taacagctca aatattaaat aactttttag
     7441 aaaagctgcg ttaatatgtt atagataaac aactagtgac ttagacgtag gatatatctt
     7501 aacgaaagaa gttatattct ttttgtctgt tgctatataa ttttgctgta gatttctaac
     7561 agtagaagtt atataaattc catgttctta aggaaagttt atgacaagca ggaataggtc
     7621 aacttctact gaagaaatac ctacagaaaa atacagcgat attttcaaaa ctttttagga
     7681 ggaaattatg agaaatatat tttattacaa tactatgatt ggagaacttg gaatagaaga
     7741 aaatggatta gcaattacaa aagtatttct tgtagataaa gatattgaaa aaggaccatc
     7801 agaaaaaaat gagacagaat tattaaaaga agccataaaa caacttaatg aatattttga
     7861 tggcaaacgt aaagaattta atttaccatt agcaccaaaa ggaacagaat ttcaaaagaa
     7921 agtatggaat actttaaagg aaattccttt tggggaaaca aggagttatg gtgaaattgc
     7981 aaagctaatt ggtaatgaaa aagcatcaag agctgttgga atggctaata ataaaaatcc
     8041 aataatgatt ataattcctt gtcatagagt gattggagca aatggtaagt tagttgggta
     8101 cgcaggaggc atagatataa aagaaaaact tcttaattta gagaaaaatt aagaagtttt
     8161 tctttttata gatattcaac ttttaactta aacttatgtg ttgactaaca gaaagtaagg
     8221 gtactctatt gctatagaac attgctatgg atttctaata gtaatagttg ctaaattcct
     8281 gcatgttccc cagacaagct tggtacaaga tacacagaaa aaataatttt atgatatagt
     8341 tttgttatgc ttaaattata tgtaataaga aaggataaga ttatggataa atttgagact
     8401 attaaaaata atataagtga aaatgagcca acaagaaata acttattaaa agcagtgact
     8461 aatttcaaac taagtaccaa agcattacag aaaataacag gtttggaccc tgagtggctg
     8521 aattcttatt tgaataaaag agcaagtgta catgacctct cgtaccagtc aatggcggag
     8581 ttatctaatt taagttttat gttatctgat gctataacgt ttgttgataa tgatgataga
     8641 attaaaggga taattgatat attaaaagaa gaattttata taagttatga aacaatagcg
     8701 ttgtatgcta aaattgatgt aattgatgta gaaaaattta tagaagacac taaatctata
     8761 ggatttgaaa aaaaatataa aattgctacc attagttctc ttttactcta cttatcaaaa
     8821 aaatgattgt aggatttctt ctagtaaccg aaacaacaga gcaccatttc tttcggtaaa
     8881 attacaacaa aactctaaat ccaaaattat ttatctatat gtactaaaag aaaataaaga
     8941 atcataaaat ataaaaagta atccacatgg atagttattt aataaatatt ccttgtggat
     9001 tattttattt agtcacattt aaaaaataac aagtgtattt acattataaa aattaatttg
     9061 catagcaatg aaataaaaat ggttaaacaa aaatgaataa tagggaatta acttaactaa
     9121 aaaattaaaa ttgcaatata tatttaatgg aaattattaa gaatatatta aattaatttt
     9181 aattattatg aaatttattc tttaaaacaa tacaacaaga gtttataata agattaaaaa
     9241 tacaaaatat agttttaaag taataaatta acatatggat aaaaacttgg caatgatacc
     9301 tagttaaata aagtttaatt aatttaataa atgattggag aggtgattag acatgttata
     9361 tatctttagt ggataaaata ttaattttaa gcaaatttaa ttattttcac gtgcctaaaa
     9421 acaattttaa ggagtttgat aaaaatgaaa acagaacaag gcctagtaat tgaggtgagt
     9481 gataatgtgg ctaaaattaa agtaggcagg cataatgatt gtaaaaattg tggtgcgtgt
     9541 ccgggaaatg acagtattgt tataactgct actaataaga taggggcaaa accaggacag
     9601 cgagtagcct ttgaagtaaa agaaagtaat tttttaatgg ctacatttgt tgtttttgtt
     9661 ttgcctataa ttgctttgtt tattggtgta ttacttggag gagtagttag taaatatatt
     9721 ggatcaaata ttcgtatatc tcaaataata ggcggaataa ttatgttcgt gttgtcattg
     9781 atttttgtaa agtcgtttga taagactgct agtgcaaata ataaatctca gccagtaatt
     9841 gttcgtattt tataatgaga tattaaatat ctagactaat aatgaaagaa atatcttgat
     9901 taaaaaatct ctcctaatca ttaaattata tagctaaaag catttataga gatttttata
     9961 atataaatag ttttttaata agcttgtgag gtgattgtaa atgttaaaaa gttttcttgg
    10021 aggaattcat cctaatgata gtaaaaagta tacatttgat aaggcaattg aatctccatc
    10081 attaccagac gaggtagtta ttccggtaag tcaacatatt ggagctcctt gtacacctat
    10141 agttaaggtt ggtgatagtg ttaagaaagg gcaagtcata gctaatagtg atgcatttat
    10201 gcatagtcca atacatgcat caatctcagg taaagtaact aagattgcag atatgccaca
    10261 tgcatctaag ggaagctgct tatcaattgt tattaaaaat gatggtttag acgaatggat
    10321 tgaaggaatt ccattgaatc gtgaatggga caagttaaat gctgaagaaa tccgaaatat
    10381 tattaaggat gcaggtatag tcggaatggg aggtgctaca tttccgacac atattaaatt
    10441 aaatccaagt aaagataaaa agattgatgt ttgtattgtg aatgcagctg aatgtgaacc
    10501 atatttaacg gcggattata ggatgatgct tgaatatgct gatcgtatag ttactggagt
    10561 caaaataatt atgaaagtac ttggagttac taaggtgttt ataggaatag aagataataa
    10621 aatggatgcc gtaaaagtaa tgaaagatgc ttttaaggat acgtcagttg aagtagtgcc
    10681 tttacctaca aagtatccac aaggtgcaga aaagatgctt ataaaagtac ttactggccg
    10741 tgaagttcca acaggtggat tgccaatgga tgttggtgtt gtagtgcaaa atattggaac
    10801 tacagtagca atttctgatg ctgttgttaa tgggattcca ttgatacaaa gaattacaac
    10861 agtttctgga gatgcaatta aggaacctaa gaatttatta ctaagaatag gaactagctt
    10921 taagtatgca ataaattatt gtggtggatt tagtaaagat cctgaaaaaa taattatggg
    10981 tggacctatg atgggatttg ctcaatctac attagatgta cctgtaatta agggtgtatc
    11041 tggaatattg gcgttaagct ctgatgttgt aaattcagga gaagaatctc catgtattag
    11101 atgtggtaga tgtgttaaag catgtcctat gggactgata ccgagtatgt taagcatatt
    11161 aggacagcgt cataaatata aagaagctaa agaaaattac aacttattta attgcataga
    11221 atgtggaagc tgcgtttatt cttgtcctgc aaaacgtaat attgtgcaat atataaaata
    11281 ttcaaaagct caaaatttag cacacgcagc aaataagtag ggaagaaggg ataaaatgag
    11341 ttcagaagtt aaagtgcagg aaggcagttt acaagaaatt aaagcaaagg aaattggaat
    11401 agaagagaat caatttacag tttcagcatc gccacatata cgatgtgatg agtctatttc
    11461 aaagataatg tggaatgtaa atttggcatt agctccagcg gctatttttt ctatatgcta
    11521 ttttggattt ccagcattaa ttaatatggt tacaggagct gtttcagcag ttttatttga
    11581 atatctagta gaaaagtttc gtaaaaagaa aatcacagca tttgatggaa gtgcattttt
    11641 aactggattg ttgttagcta tgtctgtttc accaagtttg ccaccttata tgatgatagt
    11701 aggttcattt atagcaattg taattgctaa acattctatg ggtggacttg gatttaatat
    11761 tttcaatcct gctcatattg gaagagctgc attaatggta tcatggccag ttgcaatgac
    11821 tagctggact aaaatgacaa catctgttga tgtagttagc agcgcaacac cattaaatat
    11881 attaaagcaa caagggtata gtaaattggt tgagacattt ggaagtcaag cagcaatgta
    11941 taaggctatg tttttgggaa cacgaaatgg atgcattgga gaaacttgta ctatattact
    12001 tgtacttgga ggaatatacc ttatatatag gggatatgtt aattggcaga ttcctgtttg
    12061 tatgatagca acagtaggaa tacttacatg ggtttttgcg cctacaggac ttttcactgg
    12121 tgatccatta tttaatatga tggctggtgg tttgatttta ggagcatttt tcatggcaac
    12181 agatatggta actattccga ttactataaa aggacaaata atttttgcag taggagcagg
    12241 tgcaataact tctttaatta gattagtagg tggatatcca gaaggcgttt gttattcaat
    12301 tttattaatg aatgcagtaa caccactaat agatcgtttt gtaaaaccaa aagaatttgg
    12361 agcaaggggg taataagatg gaaggtgcac acgttaataa agaatattca atttttcaga
    12421 tagcaataaa tttgataata acttgtttag tttctggatt aataatagga ctagtgtatt
    12481 attttacagc tccaattgcc gctgaaaaaa aagaggtatc taaacaagaa tctatgagat
    12541 cattagtcag tgatgcagat aactttaaag cagtaccaga taaggaccaa tggtttacag
    12601 ctgaaaaaga cgggaaaata atagcctatg tagttccggg tgaaagtaaa ggatatggtg
    12661 gagaaattaa gatgcttgta gcggttaaac cagatggaga ggtaattgat tatagcataa
    12721 caacaagtaa tgagacacca ggacttggag ataatgcatc aaagcaacca tttaaagatg
    12781 aatttaaagg gaaaaaggaa gctaatttaa cagtgacaaa agatgcttct gacaaagacg
    12841 atattcaagc tatgacaggg gcaactattt catctagagc tgtaacacta gctgttaaaa
    12901 atgctgtaca tgaagtgaca gattttacag gaggtaaata aatatgaagg aaaagtggaa
    12961 aatttttagc aaaggtttat atgatgaaaa cccaatattt atgttatgtt taagtctttg
    13021 tcccgcatta gctgttacat catcagtaat taatggacta actatgggct tgtgcgtaac
    13081 atttgttata acatgcaata atgtagtagt ttcacttaca agaaaatttg taaatccaaa
    13141 agttagggta ccagtttata ttacatttat agcaactata gtaactgttg tagaacttgt
    13201 attgcaggca atttcaccaa cgttatatag tgctcttgga atctatttgg atttagtagt
    13261 tgttttcgcg ataatacttg caagagctga agtatttgca tctaaaaata aagtgtttcc
    13321 ttcatttcta gatggttttg gtatgggatg tggttttaca ttagctatgc tttctatatc
    13381 aataataaga gaatttttcg gaagtggatc aatttgtggt tttagaatat taggaacatg
    13441 gtataacgca cctttgatta tgattttacc agctggtgcg tttatcttaa ttggttatat
    13501 gataggtgca attaagcttc ataatgcgaa tagagaagca aaaaaagtag aagaaggaag
    13561 tgaagcataa tgaaagaata tttcacactg tttataggtg cattacttgt aaataatttc
    13621 gttttaacaa agtttttagg tctttgtata ttttttggag tttctaaaag cttaaatgct
    13681 tcaataggaa tgggcatggc tgttacttca gttataactc ttagttcgat gttagcgtgg
    13741 atagtatacc attttgtact attaccattt aatttaacgt tcctaacaac aattgttttc
    13801 gttatactta tagcaagttt tgtacagcta ttagagttga ttataaagaa acaagcaccg
    13861 acgttatata ggatgtgggg aatttatctt cttttaatag caacaaactg tatagtatta
    13921 tcagttccat tattaaatgt tcaatcaaat tattcgtttg ttaaaagcat agtcttttca
    13981 ataggctctg gtatgggatt tgcacttgca ttaatactca tggcaagttt aagagaaaag
    14041 ctggtgtatg cagatgtacc aaagccacta gaaggaacag gaattgcttt tatattagca
    14101 ggtatgttag cattagcatt cttgggattt tcaggaatga tataaaggag atgaatagag
    14161 attatgttta ctgtaataat ggttttagca gtaatggttg gaattgggat tgtttttgga
    14221 ttcattcttg ctattgcaaa taaaaagttt tcagtggaag taaatccact tattcatgag
    14281 gtagaggatg ttcttcctaa gggacaatgt ggtgcatgtg gttatgcagg atgtgcaggt
    14341 tatgcagaag cagtagtgct aaataaagaa gtaccaccaa atctatgtgt acctggaaag
    14401 gatgctgttg ctaaattagt agcagaaatt acaggtaaaa gtgctgaaaa agtagaacca
    14461 agaatagctc atattaaatg taaaggagct attggaaaag caaagctaag ttataattac
    14521 aagggtatag aggattgtgc agcagcaact ttacttcaag gtggacctaa aggatgtaaa
    14581 catgggtgcg taggatttgg aacttgtgtt aatagctgcc catttggagc attgtcaatg
    14641 ggagaggatg gattacctaa agttgatgca aaaaaatgta caggctgcgg aacttgtgaa
    14701 acagcttgcc ctaagaatgt catagaagtt atgccagtaa attcgattgt aaaagttaat
    14761 tgtaattcta aagataaggg agctatcgct agaaaacttt gtagtgcaga aacatgttta
    14821 ggatgtggaa tttgtgcaaa aaattgtact tatggtgcta ttaagattga aaataatctt
    14881 gcagtagtag attctaaaat atgtgttgaa aaatgtaaag aaccaacatg tttagctaaa
    14941 tgtccaacat cagcaattaa aattgctaac taattaaagg atatttaaat tatgaaatca
    15001 tatatagggt ttaacaatga gaatttaact tatattattt ttttgaatgt accttagatt
    15061 attgatagtt tatattttga gttttcattg gggaatccta tgggtgattt cacattaata
    15121 atcggaattg tattaaggca caattaaaga ataatatcag tatgtgtgat tagttagcat
    15181 catactacaa ttctattaat acgtgtgcta ttagcaggat ttacttgttt gtctcacgca
    15241 aaatattggt ggaatatttt gaaccgttat tttttgatgt gtctaaaaat gtttttttga
    15301 aatattttcg ataaaaatag attggagtaa tcatatgaag aaaaatatat gtgcaatact
    15361 agtttttatt tcaattgttt taaattttac ttcttgtgat agtagtagaa ataaatatta
    15421 tgaaaaaagt aatatagtta tggatacggt agtcacatta agtgcttatg gagaaaattc
    15481 taaagaagca gttgaggaaa gttttaaaaa gctagatgaa attaatgaaa tggcaagtac
    15541 taatattgat actagcgata tttataaaat aaataattca tcaggagaaa gttatgtaca
    15601 ggttcatcct gaaattatga agatgataga aacttcaata aaatattcaa agttaagtga
    15661 tggagcattt gatattactt taggtcctat aattgattta tgggggattg gaacagataa
    15721 tgaaagagta ccttctgatg aagaaataaa agctaagtta ccattagttg gatgtgataa
    15781 aattagcatt aatgaagaag aaagtagtgt tatgcttcaa aaaaaaggta tggctttaga
    15841 tttaggtggt attgctaaag gatttgcagc tgatgaagtc ttaaaaattt ataagaaata
    15901 taatattgaa aatggtctta ttaatttagg atcaagctct atttacgctg ttggaaaaaa
    15961 taaagataac aataaatggt ctgttggaat taaacatcct agaagtgaag attctaagaa
    16021 ctatcttggc ataattaaat taagtaatga agcattatct acatcaggtg attatgagag
    16081 atattttata aaagataata aaagatatca tcatataata aatcctaaga ctggatatcc
    16141 agcagataat ggtgttatga gcgatacaat ggtaatagat aacgatgatg aagataaaaa
    16201 tatgttagca gatttattaa ctacaacagt atttatatta ggacctgaaa aaggattaaa
    16261 tcttataaaa actttaccta atgtatcttg tgaaattaca acatcagatt ataaaattta
    16321 tacatcagat gactttaaag atagaattac agatttaaat aaagaatttg aatttgcaaa
    16381 ctagtaaagt aaaatatata tgattttgat atagataaat aatttaagaa ttagacttat
    16441 aactagaatg tatggaattt cggttagtga tcacataact ctagattata gtttggatat
    16501 ctataaagat taattttaag aggaactatt atgtttaaaa agtgggatat aattattata
    16561 atttttttaa tatgtttatc atttattcca gagattattt ttggagtagc aatgggtaaa
    16621 aattataatg gaacttatgc agaaataact ttagatggca agctttataa aaagatactt
    16681 ttatcagagc ataggggaaa agaagaattt gatataaaaa caaaatatgg atataacgaa
    16741 gttgaaatta atgatcaatc tattggaata cttgatgcag attgtccaga taaaatttgt
    16801 gtccactctg gatttatatc agaacctgga caaatttcag tttgtcttcc tcataaatta
    16861 atgattgaaa ttaaaagcag caacaatgaa aaaaatcttg atgtttcata aatatatttg
    16921 gaattaattt agatatattt gctgttatgt atacttttaa caatatttat atcgatagag
    16981 ataacggtga aatggaggtt aaaatgaaaa aaacatttcg aatagttttt ataggtcttt
    17041 tagtttctca agctttggca ctttatacaa ttgaaagtat gattccagta cctttcattg
    17101 ctcctggtgc caaacttgga ttaacaaatt taattactgt catagcttta tacatattaa
    17161 ataacaaaaa ggatgttttt ctaataatat tattgcggtt attgttatca actatattca
    17221 atggaagctt atctacattt atgtatggtg ctgcaggtgc aattctcagt tattatgtaa
    17281 tgatatttgt taaaaaattt ggaaaagata gagtgagcat agtaggagta agctgttctg
    17341 gagcggtatt tcacaatatt ggtcaattag tagtagcttc agctatagtt caaaatatag
    17401 ctgttatgct ctatttacct atattatcga tagcaggaat tggtacagga atttttattg
    17461 gagtgactgc aaattttgta gttaaacatt tatctaagtt accatatttt aaaagtctga
    17521 atttagactt atgaggtgac taaacgaaag taagggtact ctgttgctcg attgctatag
    17581 aacatagcta tggatttcta acagtaagag ttgctcaatt cctgcatgtt ccccagacaa
    17641 gcaagaattg aacaactttt actgaagaaa tacctatagc catattctaa atgcaatgct
    17701 cgcaaaagag tacccttgct ttctggtttg gaatgtattt caaagtttaa agctaattta
    17761 taatttgttg tataaaatag actttttcgc atccttctat agatatctaa tttaagattt
    17821 agacttataa ttagaatgtg ttcccatact agaaattaca taagtttaag ttatttatct
    17881 ataatttaag atataaaatc aatagatttg tttataaaga tctttaactt ttagattatt
    17941 tttcttagcc atggatttcc aaccatgatt gcctgcaagt ttaaatataa gtttagacat
    18001 ttttgcatta gtaaatatat tatttattga attattagaa ttatcttcaa tatcattttt
    18061 taaagttaag aaagcgttat aaacaggttt tttcatacga gagtttaaag gaatgttttt
    18121 agagccttta agaaattcac cgccacctat accaagacca aatcgccagt taaaatttat
    18181 tctcttagaa taatttttta aaatatcaag agctatttta ttttgaatgc cttctaagaa
    18241 tccacaatta acaagtccat acatatcaat atttggagtg tttttgtctt taagaaaatc
    18301 ttcaaatgta gcaagaaaat ttaacattgt gcttggaaaa caatctgcat ataaagggga
    18361 aatgaaaata actttatcat ataataaaag ctcatttaac gaattctcat tgttaacaag
    18421 attgcttata tagtattctt ttgatttaac attagtactt aataatttag ttaattcgtt
    18481 tataagataa ctagaagtac cttttccttt tcttggactt ccatttataa tacataaatt
    18541 aatcatagaa taaaccctcc ctacaaattt ttaagtattt ttttagattc ggatatatct
    18601 ttaattatat aaacttcata gtctggaata cataaattaa tagcatttct tctaactaaa
    18661 tctttaaaag tttcttcttc atcaaaagta atatttttat tatatcctat tacaataaat
    18721 ttaaggtctt ttttataacg aggaagatga tgaagctcac cattaactgt ttgaaaaaaa
    18781 ggcaataaaa tgcctattga tctatcaatt acatttttta cgtaagaagt atagcagcca
    18841 tattttattt cagttagaat tacaaaagta tcaccttcta aaatatattt tggcatttct
    18901 gtataggaat cttcgataat gcatctacct ggtgtcttga gccaacaatt aaaacatcct
    18961 aagcaaccat taatattatc tatctctttt gaaagtactc ttgaattagg aggtaacaca
    19021 gatgtaagtt cttttgaatc gtcaacattt aaatcatgaa ttaataacat agaaagtctc
    19081 ctttttattc acagaaatat atacaaacta acaagtatat atttgttgaa attttatatt
    19141 tatttgtaat ttttatatta gggtaatttt aagttatatt tattaataaa tatatgttta
    19201 cactgtcaac ttaatgatag agtagcactt aaagtttaca ctgtcaacat gttatgatat
    19261 tatatagatt acaaatttaa tttttcatta aaatcaagtt tctattacta aattattttt
    19321 gaattataca tatgttgcaa tatgatttgt gaattgattt atttatacag tacatagttt
    19381 taatgtagat ttcaattttc aatatatatg ttaaaaatat tatagataat ataaaaaaag
    19441 tattaataat atattttgaa ttttagtaaa tttatatata aaatttagga aagaggtttt
    19501 acgtatgcag gtcgataagt atcatcacgg agatttaaaa gaaagtctaa taaagatggg
    19561 actaaagtta tttaatgaag aaggggcaga aaaattttca ataagaaaag tcgccgcaat
    19621 gtgcaacgta agtcattcag ctccatataa acattttaaa aataaagaag aactgattaa
    19681 tgcaatatct gaatatgtat tttataactt taaaaactca ctaaatgaaa tcgtggagaa
    19741 gtataaggat aatccaggtg aaagaattat acaattggga aaaaaatatg ttgcttttat
    19801 ggtagaaaat ccagattatt tgaaatttgc gtttttaaca aattcagagt ataaaataac
    19861 tatagaaaaa aatacactaa aaagtgaaga gtgtggaacg tttaaagtat ttgaaaattg
    19921 tgcttttgaa tttttacaaa gtgtaaatgt taaagaagaa aaatatgcac aagacataat
    19981 tgccatgtgg tcgatggtac atgggcttgc tacgatgttg tcaaataaga catttacata
    20041 taaaggagat tatcttagtt tggttgaaaa tatattaaga aataatctta gattttaaat
    20101 tgtggagcta aaatgtaaaa ttgatttaaa tttatataaa ggagattatt attatgtata
    20161 atatgaaaga agaatataaa attggattag atcatattga taagcagcat gaaaagcttt
    20221 ttgagttggc taacaaagca tatatgttat taaaagatga atttgctgtt gataaatatg
    20281 ataaaatagt agaaataata aatgaattaa aggagtacac tatttttcat tttaaatcag
    20341 aagaagaata tatggaaagt ataaattata agggattatt tagtcaaaaa ctacaacatg
    20401 aaaaatttat taatgttctt caagaattag atttcaagca gattgatgaa aatcaagatg
    20461 aaagtttgat aaaagtgtta gattttttaa atgattggtt atctgatcac atattaataa
    20521 gtgataaatt tataggaaaa taaggaacaa tcaaaaaaat aatagtctat tttttgcatt
    20581 ataatcatat ttatttaata gattaccatt aggtaaacat attattttct tatttgattg
    20641 taaaaatata ttatagacta atttattttg ttatagatgt tgttgtaata tgattaatta
    20701 agagatataa taaaattaat aaaaaatata tcttcagggc agggttaaaa tccctaccgg
    20761 cggtatagcc cgcgagcttt aatttaagca gattcggtgt aattccgaag ccgacagtat
    20821 agtctggatg aaagaaggta acctattagt atttaagagt ttagttattc ttatttattt
    20881 gaatgtatgc cctgatgtat ttaacatcag ggtttaattt ttttgttaat gaatttaaaa
    20941 taagattatt ttcaaaggct aaatactaat aagctacacc aggagataac ttttgggagg
    21001 caaagaaaat gaatgaaaaa acaagtaaac tagtaaaaat ttctttatta tcggctatag
    21061 cacttatact taggtatata gaatttccag tattaccact attcccatgg ctgcaaatgg
    21121 atctaagtga tgtaccagca atgttaggga catttggttt tggaccaata gtaggaataa
    21181 taattgaact attgaaaaat gttttaatat taggaataaa gggaacaagc actgcttttg
    21241 ttggagaagt tgcaaacttt ttatttggag tagcactatt agtaccagca ggacttgtat
    21301 atcataagaa gaaaagtaag aaaactgcta ttataggcat gatattaggt ggtattttca
    21361 tggaggtagt agctattata gtaaatgcat atttcttatt acctgcttat ggaatgaata
    21421 tggacagtgc tcaacttatg caatatatta ctttaggact attacctttt aatggaataa
    21481 agtctgttat agtatcagta gtaacatatg tattgtataa aaaaatatct gtgtcaatat
    21541 ttaaagttga acctaatttt ggtggttcta aaaatagtgc aaaaactatg taagtagatt
    21601 ctgcaaccaa gataaggaca gagttagcaa tcatagaaaa gtaaaaatat agtttaagaa
    21661 ttaaattaaa aaatacatat aaattgcaaa gagatttata tagaatctaa gcaatttata
    21721 tgtattttat tttttattaa acttatgcat atatatctaa ataagtgata ttttttagtt
    21781 gcttaatcgc tttactataa gtttaaatgt tattaagaat tttaactttc tcttagccac
    21841 attaatatgg catcttcttt attgtcttca taatatcctt ttctaactcc atctttttta
    21901 aaaccatgtt taagataaag cttttgagca ttttcattgc tagctcttac ctcaagagta
    21961 taagcaatac atcccttaga cttacagtat gttagcaatt catctaataa tttagaagca
    22021 attccttgcg ttctatagtt agggtgaaca gctatatttg ttatatgaga ttcgtctaat
    22081 ataatccaag taccaacaaa tcctactact atatcatcac atcttgcaac aaagtaatgt
    22141 gctattggat tatttaattc ttgaatatag gattccttgc tccaaggaag agaaaaactt
    22201 aaggaactga tatctaaaac tccatcaata tcttcctctt ccattaaatc aacagttaca
    22261 ttcatttctt aattgcatcc tttgttcata ttctctctca gcttgtggct tctttaaata
    22321 gaatggagtg gagttaggat catcaaattg accatctctt agcaatttac tacctatttc
    22381 acctagagat gatgcacgaa ctaaatttaa gtgatttgga gggaagtaac aatttggaca
    22441 attttcaatt agataatctt tgtatttatc taatccatct ccaataaata ttactttttc
    22501 tcctttagac ttaattattt ctacaagttc atccatatca agtgcagaat aatccataag
    22561 tttttcaagt gaaccattgc aactcttata taatgaagta taaacgctat ttcttagagc
    22621 atccattatt ggacagataa gtccatcaaa attagcaacg ctaaatgcta aagcgtctaa
    22681 gctggatagg ctaacataag gtttaccgct tccaaagcta agtcctttta ctgttgccat
    22741 tcctattcta agtccagtaa aggaaccagg ccccttagaa acaacatagc catcaatatc
    22801 atcaatagtt aaattattaa attttaataa atcttcaatt atagtcatta atataacaga
    22861 atgttctttt ttatcattca aagtaatttc gccaagtaat ttatcatctt tcattaaagc
    22921 tacagttgca actttagaag aggaatctac agctaataca atcatattgt cagctccttt
    22981 atataattat atctttctcc ataaggagtt aatattattt ttctgtaatc ttcaccttta
    23041 gcaagatctt tttctatata tatatgaagt aaatctttag gtagaatttc ttctatataa
    23101 tttgcccatt ctataacaga tacagcatct gaaaatatgt aatcatcaaa tccaatagca
    23161 taaacttcat caggatcact tactctataa acatcgaagt gatttaattt taaacgtcca
    23221 ctatcatatt catttacaat agtaaaagtt ggacttgtaa tagtctcatc tatacctaag
    23281 ccttttgcta ttccttttgt aatgtgggtt ttaccagtgc ctaaatctcc agttaaacag
    23341 attatatcac cagcatttaa taactttcct aattttattc ctaattgagt agtttcagct
    23401 acactattaa tttcaaattt catggaatac ctccttcaaa cttttaaaga gaatgaatgt
    23461 aagataattt taggcacatt ttgattgtac cttatataaa atttctcatt cttttatttt
    23521 atatcaaatt ttcataaaag caaattaata aatgttatta ttgatttatt tatcaaagct
    23581 agatagaaat ctatagtcca gttgtataac aacccaaaaa aagaataaag aataaagttt
    23641 atttcagtaa gttgtatgat aaatctaaaa ttgggattta tttatctata acaactttac
    23701 gaaatagaat ttatgatgat ttttagaata ttcaattgca gtttaaagct acataaaatt
    23761 gtaataaatt tatatatatt tatttgtaat tagttggtat aatagatgta aatgcatatt
    23821 agaattaaaa tgatagataa ttaatttaca tgaatgttga cttaaattga ttttttcgat
    23881 aaaatttgga tgcacataaa gtgaattaat aaatagtata aggttaaaat aagtatataa
    23941 atgaacgtga cagataaata ataaatgtaa gattgattaa cgtgaaaata aagtttttat
    24001 gaaaagtaat ctgatttttt cgggggtgac ttattttgaa gaagattaca tttgctatgg
    24061 tattaataac tatagtattg tctttaggaa tgagtgtatt ttcaagtcct ttgctagcaa
    24121 atactgagaa taaaagtaat gctgaaatga gagataaata tttaaatata atgactgtga
    24181 ataagccgca atatgatatg gtaaagaaaa ttataaagga caagcacaac gttcaatata
    24241 tgtttactga tgaaaaggaa atcagtgaat ttaaatataa tgcaagtgtt ttggaaaacg
    24301 tatcaaatat ggatttattt atatattctg gagctacttt tgaaccttgg gctaattcat
    24361 ttattagtga attgacaaaa ggaaatctag gaataattaa tttatccaga ggagtaagac
    24421 ttttaaatta tgatgaaggt gcaactaagg aaaatcctta ttactttgag ggtatagacg
    24481 aatataaaat agcgttatgc aatgtaaagg cagctattga agatagagat cctaaaaata
    24541 gagattttta tgaaaagaat tataatattg caattaaaga atttaatgat aaattaaaat
    24601 cttatgatga taagataaaa tcgcttagtg actatacatt tataacatta aatcatgatt
    24661 ttgattattt gactaaatcc ttgaacttaa atattaaaga acttaataat catgaactgg
    24721 gtgaatttat aaaaagcaat aatttagatc ctaaaaaagt tattgttata gtagatggag
    24781 aacaagatcc aaaaataaat ttgtctggat ataatacaat aaagttatgg aaatattatg
    24841 gagattggtc ttttgatgac ttgattttat ataacataga tgaattagca aaatgggcaa
    24901 aaccagcaga taagagttca actggaagcg tggcataata attgttaatt ataatatgta
    24961 ttaaaaatta aat
//
