LOCUS       NC_022571.1            34357 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_022571.1 Clostridium saccharobutylicum DSM 13864, complete
            sequence.
ACCESSION   NC_022571
VERSION     NC_022571.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:58:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 359164
            Orig. end    :: 393521
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..34357
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[369164:383521]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..24357
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..34357
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..34357
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="2"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             94..1323
                     /locus_tag="ctg1_301"
                     /transl_table=11
                     /translation="MRNKFIFFDIRRNGIVSILIIIEIALWIFYTASLVSLINFDNSYR
                     KRYNRAISIDNSEIMTFYKMINNDNSDEDHDTYINYIKETLKVIKNSNYTYGFIQRDMN
                     ERFPIETFGFTPKELFGNFTEMDELNSPDNPIGFNYGMIENYKKNIIGEIYEDDWTRSD
                     NYIPVIVGNEIGEKVHIGDSYVSNNITYKIIGIFKKDTLAFDYTSSVDSSFLLNTSFVI
                     PLSEEKFFDNFGHEPITIFFNGDKQIGSKNLNPAIESISKDIVISNFEDDLNKFLDELK
                     TKKYYEIFRIIIITIIASTSIITTINYKINEDRSRIGILYSFGVSKLNIFKTFSAEFFI
                     SIILGIIGGSLFYLKNCKSVYVFFINENILFNLNISIGILLLLIILIMLVGFSQINKLT
                     PKEMIGGFVE"
     CDS             1320..1994
                     /locus_tag="ctg1_302"
                     /transl_table=11
                     /translation="MSILDVRNIYKIYGKDNSKVIALNGISLKVNSGEVVAIMGPSGCG
                     KSTLLNILGCIDAPTQGESYIDGTQVNFKKLNNLSEIRNKKVSFIFQNFALIKDLSVLE
                     NIILPLKFRGISYKERVNKAKKYLKELEIENFKNKNIRELSGGQQQRVSIARALTQESE
                     IILADEPTGALDEINSIKIMEVLKELNKKYNKTIIVVTHDNLVASFCDRILKMKDGCWD
                     NN"
     CDS             2291..2962
                     /locus_tag="ctg1_303"
                     /transl_table=11
                     /translation="MKKIFIRYTLFTLLTMISISSTAFAKENTSKEDTNAQMKQLIDKS
                     KHDSDELIKNWDKLKVTKASKQSRRINTINSFDSEAAPNSVGSYGDILVTPATVFGTGP
                     ITGHAGMVDLNPDLTIESMTSAGVRRYTNDWKTRYSKALCATVKNSNPRQAVDYAISKI
                     GSDYNYNFLNKWKTDKFYCSQLVWRAYIEQGIDLDKDGGNAVLPTDLVTDKIDINWRTN
                     Y"
     CDS             3152..4177
                     /locus_tag="ctg1_304"
                     /transl_table=11
                     /translation="MYKNKKIYFLLSVIIIMILSLSFVLLHNRELKNICLIYSDSIEED
                     SEIVYLDRNFTIKKNIQIPARDIVTSCNKKDTVLLPTLSDNKLFEVDKDGIVKSSETDF
                     GGNYIRCKNNEELILYNVSLEYNRINFISSDSQKKSLDIKESLLLSGDFDDENVYILGY
                     KFDQNKEGDTFLFIIDKNDFKIKDQIKLMKNMRIYDTSLIDGKLFIGVDSKVDYLLYYD
                     VKKSTLNKIEYKEYIKDGIMDTKKILYNDKYIFYLFLDGNILKLNRKDLNIIKNIKLNN
                     KIILSGCLDKNQLYSLSVDINKNNQIGLVDVFDIDKLNNINNFSVGPIRNTTPRDIFIL
                     Q"
     CDS             4199..4531
                     /locus_tag="ctg1_305"
                     /transl_table=11
                     /translation="MKKILTIIAPSILTYTYIFIDSHFPYSKWILIGIYILFPIMFIAQ
                     TIISFGSIKNMLIGFLLLSLSIIVPINEWYKVGSMIVPIIIYSSLGIITFFLSKTINTV
                     KRKWKK"
     CDS             complement(4901..7564)
                     /locus_tag="ctg1_306"
                     /transl_table=11
                     /translation="MKNFFSKNIKDSLKEFDVTTNGLTNKKARELLESVGENVLNERKK
                     KSTLSVFIDQFKDLLVIILIIAAVISMATGNIESTIVILAVITINSILGTVQYIKAEQS
                     LASLKSLTSPNAKVIREGIKVEIPSKSVVPGDILILEAGDLVVADGRILENFSLKVNES
                     SLTGESESVDKISYVIDKDEVALGDQKNMVFSSSLVTYGRATVLVTNTGMNTELGKIAT
                     LMEETQEKSTPLQASLDAFSKKLALAIIGICILVFGLSLYRGTNVLDSLMFAVALAVAA
                     IPEALSSIVTIVLAIGTQSMAKENAIIKKLKAVEGLGCVSVICSDKTGTLTQNKMTVKK
                     IFVDNKLVNANEIDLKNPIAHFLLTSSILCNDSTSIDGNEIGDPTEVALVNLGHDYSIS
                     EIDCRKNHSRLSEIPFDSDRKLMSTLHKIDGKSTMITKGALDVLLDRVTSIKTIHGLKR
                     FTNEDKTHINNINKKLSSQGLRVLAFAYKELNENKNIDLEDENGFTFLGLISMIDPPRE
                     ESKSAVTDCLKASIKPVMITGDHKITASAIAKEIGILQEDDLAVEGLELDKMSDNELFS
                     KLEHISVYARVSPEHKIRIVKAWQNKGKIVAMTGDGVNDAPALKQADIGIAMGITGTEV
                     SKDAASMILTDDNFATIVKSVTNGRNIYANIKNSIKFLLSGNMSGILAVLYSSLFALPV
                     PFAAVHLLFINLLTDSLPAIAIGMEKSKKDVLRDKPRDANESILSQDFIKDVCIQGLLI
                     GIFTMISYHIGLTKGSDGLAMTMAFSTLCLARLFHGFNCRGRKSIFSLGVFNNTFSWIA
                     FIVGVILVNAVLLIPGLQGLFEITPLATSELLSVHLFAFLPTLIIQIFKVIRDIVESKK
                     EKIEIENDNESKVQAA"
     CDS             7903..8745
                     /locus_tag="ctg1_307"
                     /transl_table=11
                     /translation="MTGLVLEGGAFRGLFTAGVLDALLDIKAEIKYVIGVSAGATNAYS
                     YISKQKGRNLEIMERFINHKRYVGYGNLIKSKAIMDLDFVFDEIPNKYCIFDYKTFSNY
                     DGKMLVGALNIETGESEYFDKDELDDKNSILRATCAIPMLFPFAKIKNSYYADGGLLDA
                     IPIKKSIEDGNDKNIIVLTRNEGYRKKQSKANKFTYKFYKNKYPKLANVLKNRYIQYNK
                     QLDYCKELEENKKAIIIRPTIKMDIGRFERNKNKLKAIYQNGYDLVIRDKDKILYYLK"
     CDS             8837..9529
                     /locus_tag="ctg1_308"
                     /transl_table=11
                     /translation="MLTNIKTPKVYDQVIEEIKNKIKNGEIKKGDKLPSEREMAESLGV
                     SRTSVREALRALEVIGLVESRQGAGNYIRTNFNNSLFEPLSIMFMLQESSPKEMYDLRE
                     TLELQCAKLSAKNIEDNELELLTAILDRMYVAESEEESLELDIKFHYLLAKTSRNVLLI
                     NVVEVISQLMDEFIKKSRMQILHEGNTRENLLDIHENLVRALKCRDELKVSSAMKEHFD
                     LIRKAYGY"
     CDS             10001..10789
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 145.9;
                     E-value: 4e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_309"
                     /sec_met_domain="ETF (E-value: 2.8e-43, bitscore: 145.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILVCIKQVPGTSKVEVDPVTGVLKRDGIDSKMNPYDLYALETA
                     FKIRESKGGNVKVLSMGPNQALSVIKEAYTMGADEGTLLSDRKFGGADVLATSYTIAQG
                     VKKMGDFELIICGKQTTDGDTAQVGSEMAEWLNIPHVANVKSIVEVGDSSITVEMDMPE
                     SIETVKIAYPCLITVDKGIFEPRLPSYKKKLSTKDRDIKILSLNDFDDNDEKHYGLNGS
                     PTQVERIFPPEVNNDREMWTGSSGELSGRIEKKLKELKFI"
     CDS             10845..12035
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 145;
                     E-value: 7.5e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_310"
                     /sec_met_domain="ETF (E-value: 5.3e-43, bitscore: 145.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 9e-34, bitscore:
                     113.4, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKLVVNQEKISNIEELIKICPFGALENHNGIVEISGACKMCRLC
                     VKKGPKGAVEYIEEEIKKIDKSLWNGIGVYVDHVNGEIHPVTYELIGKAKELASKINQQ
                     VYAVFIGSNIASKAEEILHYGVDKVFVYDDDELKYFRIEPYTAAFGDFINNVKPTAILV
                     GATTIGRSLAPRIAARFKTGLTADCTILDIKENTDLVQIRPAFGGNIMAQIVTPNSRPQ
                     LATVRYKVMTAPKRSEKVTGEIVNCKIEKGKLRSGITALNIKKKDTEVGISDAEVIVAA
                     GRGIKSEKDLELVKQLAKVLGAEFACTRPLIEAGWVDAKRQIGLSGRTVRPRLIITCGI
                     SGAVQFTAGMNNSDYIFAINTDEKAPIFEAAHYGVVGDIYEVIPQLIEKIKMAKEA"
     CDS             12039..13442
                     /locus_tag="ctg1_311"
                     /transl_table=11
                     /translation="MDYKEVELKDYEYILSVTGNDRERVFFKDGINEDYSHDELGGIRQ
                     MPDVVVQAISTEEVSSVMKYAYENNIPVTPRGSGTGLVGAAVPLKGGIVIDLSKMNKIL
                     ELDEENLTLTLESGVLLMEIGKYVEQFDLFYPPDPGEKSATIGGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEVVNLGGKVVKNSSGYSLKDLIIGSEGTLGIVTKAILRLLPLP
                     KKAVSLLIPFESLERAIETVPKIIKSKSIPTAIEFMQREAILAAEEFLGKSFPDKSSDA
                     YLLLTFDGNSIEEIEKDYENVANICLECGALDVFISDTEERQESIWSARGCFLEAIKAL
                     TTEMDEVDVVVPRNKIGDFVTFTHELECKSNIRIKSFGHAGDGNLHVYILRDELDEESW
                     HTKLSEVMQIMYDKAKELQGQVSGEHGIGFAKKGYLKQSLPNECIDIMERIKLAFDPKN
                     ILNPGKVCE"
     CDS             13613..14887
                     /locus_tag="ctg1_312"
                     /transl_table=11
                     /translation="LKEQDKELTSKVIEFDKKETHQCGICGEDAICFNTDNNIWLCEKC
                     NDIQDGMDKFAEKMEKKLSKRVYSFDINELLNCLSKDEIYNIARNLGANKISNLAKGKL
                     IEKLNSEYKALIEQRLYLFEEERYKILKSYVDNEGIKNFDDIDEEEANKSAYFIQQGFL
                     FPTVKDEESLFLMPKLVQDLVKEKNNIEYRRLLKNNGEIINIYRGMNQAYGILEIEASK
                     KILARYQNIEKLQLEDLLREAAYYYNEYREEGKLFVNNQIEDYEGFVDEINANKDLEYV
                     HISKEELLNMSEENWVYNTKAGKSFYKEFTSMFSVDKDMTIAMMEDLALDIQDNEPKKA
                     VDQMLELINIENEQVRFVAAGMMTKFVNKLGLWKYKGASINDMKASEISSKQNKPIGRN
                     DLCICGSGKKYKKCCGRNGNVIPMA"
     CDS             15075..16145
                     /locus_tag="ctg1_313"
                     /transl_table=11
                     /translation="VIYGLILAGGKGSRLYPLSRADQPKQFLKIINDKSFLVNTVERIT
                     PLIDKNNIYVVTNMDYRDKIKEELQGIKDDKVFVEPANKETATCIGLSAIKLLKQDANA
                     VMVVLPSDHYIQGEKNYIDTLSQGIEIANRRRCIVTLGIEPTRPETGYGYIEMGERSSG
                     NIPTYRVARFTEKPNLEVAKDFILKGTYLWNSGMFIFRADVILREIEKYLPKLYKPLME
                     IYKSLGEENEEEVIKEQYELIDGISIDFGVMQKTRKAYVIKCDFSWDDMGSFGALSRLL
                     GNYSNNNNISKNVYIDECENCSIFGNKNLIIGFGIKDLVVVDAGDVILVMDKNKDQEIK
                     HLLNKLSEENEYSKFL"
     CDS             16497..17078
                     /locus_tag="ctg1_314"
                     /transl_table=11
                     /translation="MMNTHRIMGENIIKYANTKSIYLINNKRFIWGNIKPDCVPKYTFM
                     KHYFNESIDMVVDKIIYLSSLTLEDVYYKITIGRFSEELGVICHFLCDYFCAPHYYRWE
                     FKSTSAVKHHMMYEQRLAKLTKKFKPIGIINTNVKPQNIKEFIIQLQKQYDGMLDYKND
                     LTFSYYICDSVLNMILDNVFSNENKVNRAI"
     CDS             17479..18051
                     /locus_tag="ctg1_315"
                     /transl_table=11
                     /translation="MSVLSLILTAIGLSMDAFAVSLTTGFKISKDDRSKIALKAGMYFG
                     GFQALMPLIGWILGVKFTKYIQSVDHWIAFVLLTVIGGKMIFDGLKGEEDNEFEDVHSN
                     KKFLLLAIATSIDALAVGVTFAFLGINIIKSITIIGVVTFILSIIAVYIGKVLGNKLTN
                     KSSIVGGAILIFIGLEILVEHLGLFAK"
     CDS             18339..18974
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_316"
                     /sec_met_domain="CoA_binding (E-value: 3.4e-24, bitscore:
                     83.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNKNISMAVIKRLPKYYRYLGELMSNDVDRISSKELGEKIGFT
                     ASQIRQDLNCFGDFGQQGYGYNVKELYSQISTILGLDRGYEAALVGAGNIGQAVSNYSR
                     FENLGFKITCIFDANPKLIGMKIRDVEIKDIDEMEATLQSQKIDIGIICVPRKNAQNVA
                     DELIKGGVRAIWNFAPVDLIVPQNVKVENVHLSESLLTLIYLLNESDS"
     CDS             19497..20282
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_317"
                     /sec_met_domain="EC1_2-faecali (E-value: 2.8e-88, bitscore:
                     293.5, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELKNVILEKEGHLAIVTINRPKALNALNSETLKDLDTVIEDLEK
                     DSNVYSVILTGAGEKSFVAGADISEMKDLNEQQGKEFGILGNNVFRRLEKLDKPVIAAI
                     SGFALGGGCELAMSCDIRIASEKAKFGQPEAGLGITPGFGGTQRLARIVGLGKAKEMIY
                     TCDIIKAEEAYRIGLVNKIVPLENLMDEAKAMANKIMANAPKAVKYCKDAINRGMQVDI
                     DAAILIEAEDFGKCFATEDQTEGMTAFLERRTEKNFQNK"
     CDS             20364..21503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_318"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-53, bitscore:
                     179.3, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.2e-28, bitscore:
                     94.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3e-36, bitscore:
                     122.5, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFKLTREQELVQQMVREFAVNEVKPIAAEIDETEQFPMENVKKM
                     AELGMMGIPFSKEVGGAGGDVLSYIIAVEELSKVCGTTGVILSAHTSLCASVINEHGTP
                     AQKEKYLADLCSGKKIGAFGLTEPGAGTDAAGQQTTATLEGDHYVLNGSKIFITNGGVA
                     ETFIIFAMTDKSQGTRGISAFVVEKSFPGFSVGKLENKMGIRASSTTELVMENCIVPKE
                     NLLGKEGKGFGIAMKTLDGGRIGIAAQALGIAEGAFEEAVNYMKERKQFGKPLSAFQGL
                     QWYIAEMDVKIEAAKHLVYKAACKKQAGQPYSVDAARAKLFAADVAMEVTTKAVQIFGG
                     YGYTKEYPVERMMRDAKITEIYEGTSEVQKMVIAGSILR"
     CDS             21517..22296
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 168.8;
                     E-value: 3.8e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_319"
                     /sec_met_domain="ETF (E-value: 2.7e-50, bitscore: 168.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCVKQVPDTTAVKIDPKTGTLIRDGVPSIMNPEDKHALEGA
                     LQLKETMGAKVTVISMGLPMAKATLREALCMGADEAILLTDRALGGADTLATSKALAGV
                     IKTLDYDIVFAGRQAIDGDTAQVGPEIAEHLNIPQVTYVQDVKVEGSSLIVNRALEDGH
                     QVVEVKTPCLLTAIEELNKPRYMNVGNIFTTNDDQIKVMTADDIDVDKAELGLKGSPTK
                     VKKSMTKEVKGAGELVKESAKESVSYVFGKLKEKHYI"
     CDS             22319..23326
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 181;
                     E-value: 7e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_320"
                     /sec_met_domain="ETF (E-value: 5e-54, bitscore: 181.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 5.5e-37, bitscore:
                     123.7, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIADYKGVWVFAEQREGELQKVSLELLGEGRRVADKLGVKLTAL
                     LLGSNVEGLSKTLAEHGADEVLVADNKDLQHYTTDAYTKVICDLANERKPGILFVGATF
                     IGRDLGPRVAARLNTGLTADCTSIDVEVENGDLLATRPAFGGNLMATIACPEHRPQMAT
                     VRPGVFEKVNTDGANCKVEKVEVKLTNNDLRTKVLEIIKSKKDIVDISEAKIIVAGGRG
                     VGSKENFELLGELAKVLGGTVAGSRAAVEKGWIENAYQVGQTGKTVKPSIYIACGISGA
                     IQHVAGMQDSDMIIAINKDETAPIMKVADYGIVGDVKNVLPELIAQAKEIISAE"
     CDS             23509..24357
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_321"
                     /sec_met_domain="HCDH (E-value: 8.8e-38, bitscore: 126.9,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.8e-68, bitscore: 228.0,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIFVLGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVERGIAGIN
                     KGLTKQVAKGKMTEEDKEAILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDG
                     ICKESTILASNTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEIIRGIATSQETFD
                     AVKQLSVAIGKEPVEVAEAPGFVVNRILIPMINEATFIYQEGIASVEDIDAAMKYGANH
                     PMGPLALGDLIGLDVCLAIMDVLFNETGDSKYRASSILRKYVRAGWLGRKSGKGFYDYS
                     K"
     CDS             24723..25889
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     397.9; E-value: 1.2e-121)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_322"
                     /sec_met_domain="Fe-ADH (E-value: 8.5e-120, bitscore:
                     397.9, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRFTLPRDIYYGKGSLEQLKNLKGKKAMLVLGGGSMKRFGFVDK
                     VLGYLKEAGIEVKLIEGVEPDPSVETVFKGAELMRQFEPDWIIAMGGGSPIDAAKAMWI
                     FYEHPEKTFDDIKDPFTVPELRNKAKFLAIPSTSGTATEVTAFSVITDYKTEIKYPLAD
                     FNITPDVAVVDSELAETMPPKLTAHTGMDALTHAIEAYVATLHSPFTDPLAMQAIEMIN
                     EHLFKSYEGDKEAREQMHYAQCLAGMAFSNALLGICHSMAHKTGAVFHIPHGCANAIYL
                     PYVIKFNSKTSLERYAKIAKQISLAGNTNEELVDSLINLVKELNKKMQIPTTLKEYGIH
                     EQEFKNKVDLISERAIGDACTGSNPRQLNKDEMKKIFECVYYGTEVDF"
     CDS             26201..27136
                     /locus_tag="ctg1_323"
                     /transl_table=11
                     /translation="MDYKSIRECNEYILIESIKNFKLKQIFECGQCFRFEKISDTNYIV
                     VAFERVIELIEDGENILIYNSNESDVRDIWIKYFDLHRDYSYIKNELSKDDLLRKSIEF
                     GTGIRILNQDPFEILISFIISARNSIPSIMKTINKISTKWGTEILYKGKTYYAFPTIEQ
                     IKNATLEEIQETGASFRSKYIIDTIANVYSSKQAMNQESLQKREELKKYDLDYIKSLND
                     DDCHKALQEFKGVGAKVADCVMLFSMEKYSAFPVDVWVKRAMIHFYGAQDASLNKIRIF
                     ARNKFGKLSGFAQQYLFYYARENKIKIDEE"
     CDS             complement(27210..27506)
                     /locus_tag="ctg1_324"
                     /transl_table=11
                     /translation="MAQNHICELCNRNVSIITEHHLIPLEKGGKHFKIAYLCTTCHTQI
                     HALFTNRELASRYNSLNSLKNDIRIIKFLKFIKDIPGDSYISIKKSKHVRKSS"
     CDS             27676..29163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_325"
                     /sec_met_domain="Fer4 (E-value: 6.8e-09, bitscore: 33.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00035, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKFENQLLKLKHEVLTRVAVLAKENKVTKEEIEKIPYNMISGES
                     PTYRDTVTQERDVVLERAKLAAGYLPNGKEGKDLIDISEQQQILYVIKAACDRCPTKKF
                     EVTDACRNCIAHKCQSTCNFGAISYVNGRAFIDPSKCRECGMCKKACPYDAIAEDMRPC
                     KRSCPTGALNFNSKDLSAEITEDKCVNCGACMAACPFGAIEDKSSLVKVINNLVSKEKI
                     YAVVAPAITGEFGPKTTYGQVKNAIKSLGFTDMVEAACGADAVTVHESNEFIERMENGD
                     PYMTNSCCPGFLSYIQKIMPDQAERISGTVSPMVAAGRYIKSKDNGAKVVFIGPCTAKK
                     SEILIDSIKDSIDYVLTFEELLALFEAFEVNPATCEDIMVDDASIFGRGFGMGGGLTAA
                     IENYIQDKGAEIEFKPVKVSGGAEIKKTMTMAKAKKLQGNFIEGMMCEGGCINGTAKIA
                     PLMKAKMPFTKNNAQSSMKSVLSNKALEEYKNINLER"
     CDS             29577..29861
                     /locus_tag="ctg1_326"
                     /transl_table=11
                     /translation="MNIKPLGDRVVIKKLEAEEKTKSGIVLTGTAKERPQEAEVVAVGP
                     GAVVDGARVQMEVKIGDKVLYSKYAGTEVKVDGEEYTILKQEDILAVVE"
     CDS             29910..31538
                     /locus_tag="ctg1_327"
                     /transl_table=11
                     /translation="MAKMLKFGEDARRNMQIGVDKLADTVKVTLGPKGRNVVLDKKFGA
                     PLITNDGVSIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLK
                     NVTAGANPILIRTGIRMAVDKAVEEIKKISKNIEGKEDIARVAAISAADEEVGKLIADA
                     MEKVGNEGVITIEESKSMGTELDVVEGMQFDRGYVSPYMATDTEKMEAILENPYILITD
                     KKITNIQEILPVLEQIVQAGKKLLIIAEDIEGEAMATLVVNKLRGTFTCVAVKAPGFGD
                     RRKEMLQDIAILTGGTVIAEELGRDLKEVTIDMLGTADSVKVTKENTVIVNGKGESAQI
                     KERVNQIKAQVEETTSEFDKEKLQERLAKLAGGVAVIKVGAATETELKEKKLRIEDALN
                     ATKAAVEEGIVAGGGTAYVNVINEVAKLTSDVPDTQIGINIIVKALEEPVRQIATNAGV
                     EGSVIIEKVKNSEAGVGYDALHGEYINMIKGGIVDPTKVTRSALQNAASVSSTFLTTEA
                     AVVDIPAKESGMPAGAPGMGMDGMY"
     CDS             31796..32209
                     /locus_tag="ctg1_328"
                     /transl_table=11
                     /translation="MKVKDNKREPYKNRKKGGFTLIEVIAVIAIIGILAAAILPRVNGY
                     IKEAKKVKVVDQSRKVVMAVESYNLKASTPLSKSTTVQTAISNEGVKKYVDESELKNLN
                     TRETSLQNCYDILDGAEFDISGDNDILDPKKIK"
     CDS             32559..34016
                     /locus_tag="ctg1_329"
                     /transl_table=11
                     /translation="MAKIIKQAYTFDDVLLVPNKSNILPREVSVKTHLTKKIALNIPLM
                     SAGMDTVTESKMAIAMAREGGIGIIHKNMTVEQQAKEVDRVKRQENGVITDPIFLSQDH
                     LIQDAENLMSQYRISGVPITTKEGKLIGIITNRDIIFETNFQRKISEVMTKENLITAPE
                     NTTVEEAKEILKKHKVEKLPLVDKEGYLKGLITMKDIEKVKKFPNAAKDGRGRLLCGAG
                     VGVTGNMMERIDALVKAQVDVIVLDTAHGHSQGVLEAVKKIKEVYPDLQVIAGNVATAE
                     AVEDLIKAGADCVKVGIGPGSICTTRVVAGVGVPQLTAVMDCAEMGRKYGIPVIADGGL
                     KYSGDVVKALAAGASVAMMGSLFAGCEEAPGEMEIYQGRSYKVYRGMGSLAAMECGSKD
                     RYFQEGNKKLVPEGVEGRIAFKGSVTDTIFQLIGGIKSGMGYLGSKDFDTLYETATFVI
                     QTAAGFRESHPHDINITKEAPNYSVGQ"
ORIGIN
        1 aattctaata ttattaatat ctatagttgt ttctatagtg gttctattta atgtgattaa
       61 ctttaaaata atgaaggaaa taaggtagtt aatatgagaa ataaatttat cttttttgat
      121 ataagaagaa atggtattgt tagtatatta attatcatag aaatagctct atggatattt
      181 tatacagctt ctttagtttc attaatcaac tttgataatt catatagaaa aagatacaat
      241 agagcaattt ctattgataa ttcagaaatc atgacatttt ataaaatgat taataatgat
      301 aattcagatg aagatcacga tacctatata aattatataa aagaaactct aaaagtgata
      361 aaaaacagta actatacata tggatttatt caaagagata tgaatgaaag atttccaatc
      421 gaaacttttg gtttcacgcc taaagaatta tttggaaact ttacagaaat ggatgaactt
      481 aattcaccag ataatccaat tggatttaat tatggaatga tagaaaatta taagaaaaat
      541 ataattggag aaatttatga agatgattgg actcgaagtg ataattatat acctgtaatt
      601 gttggaaacg aaataggcga aaaagttcat attggtgata gttatgtatc gaataatata
      661 acatataaaa tcataggtat ttttaagaag gatacattag cttttgatta tacaagcagt
      721 gtagatagtt catttttgtt aaatacatca ttcgttatcc cattgagcga agaaaaattc
      781 tttgataatt ttgggcatga acctataaca atatttttta atggagataa gcaaattggt
      841 tcaaagaatc taaaccctgc catagaaagt atatcaaaag atatagtgat ttcaaatttt
      901 gaggacgatt taaataaatt tttagacgaa ttaaaaacaa aaaaatatta tgaaatattt
      961 agaataatta taattactat tattgcatcc acatcaataa ttactacaat taattataaa
     1021 ataaatgaag ataggtccag aattggaatt ttatattctt ttggagttag taaactaaat
     1081 atattcaaaa ctttttctgc tgaatttttt ataagcataa ttcttggaat tataggtgga
     1141 agtttatttt atttgaagaa ctgcaaaagc gtttatgtct tttttattaa tgagaatata
     1201 ttatttaatt taaatatttc gataggaata ttgttattat taattatatt aataatgtta
     1261 gtaggattta gtcaaataaa taaattgact ccaaaagaga tgataggagg gtttgtagaa
     1321 tgagcatatt agatgtgaga aatatatata aaatttatgg aaaagataat agtaaagtta
     1381 tagctcttaa tggaataagt ctaaaagtta attcgggtga agttgtagct attatgggac
     1441 catcaggttg cggtaaaagc acattactta atatattagg atgcatagat gctccaacgc
     1501 aaggagaatc ttatatagat ggaactcaag taaactttaa aaaactcaat aatttatcag
     1561 aaattagaaa caaaaaggtt tcatttatat ttcaaaattt tgctttgata aaagatctta
     1621 gcgtattaga aaatataata ttacctctta aatttagggg gatttcatat aaagaaagag
     1681 taaataaagc aaaaaaatat ttaaaagaat tagagattga aaattttaaa aataaaaata
     1741 taagagaact gtcaggtgga cagcaacaaa gagtttcaat tgcaagagct cttactcaag
     1801 aaagtgaaat tatattagca gatgaaccaa caggtgcatt agatgaaata aatagtatta
     1861 aaattatgga agtattaaaa gaattgaata aaaagtataa taagacaata attgttgtaa
     1921 cacatgataa tcttgtagca agtttttgtg atagaattct aaagatgaaa gatggatgtt
     1981 gggataataa ttgaaacgta atttaaatgt tttattctta cgatatattt tagcataatg
     2041 ttgattttaa agatcaagta aatgaaatac ttttaacagt ttttgtggta ggtgtaggat
     2101 taaaacaatt tatcttatat gtattttatt taaagtttaa gcagttgcta aaactgaagg
     2161 taaaaaaata aataattatt ttaaagatag ataagttttt acaatgaggg agctaatctg
     2221 cggaaatgaa atattctaag aaactaaagt tagttgcact atcaaaaaac aaattatggg
     2281 ggaataataa atgaaaaaaa tttttattag atatactctt tttacacttt taaccatgat
     2341 tagtatatca tcaactgcat ttgccaaaga aaatacttca aaagaagata ctaatgctca
     2401 aatgaagcaa cttatagata aaagtaagca tgattcagat gaattaatca aaaactggga
     2461 taagcttaaa gttacaaaag cctcaaaaca atcaagaaga ataaatacca ttaatagttt
     2521 tgactcggaa gctgcaccaa atagtgttgg aagttatggt gatatacttg taactccagc
     2581 aactgttttt ggaactggac ctattactgg acatgctgga atggttgatt tgaatcctga
     2641 tcttacaata gaaagtatga cttcagcagg ggttcgcaga tatacaaatg attggaaaac
     2701 tagatatagt aaagctttat gtgctacagt aaagaactct aatcctagac aagctgtaga
     2761 ttatgcaatt agtaaaatag gaagtgatta taattataat ttcttaaata aatggaaaac
     2821 agataaattt tattgttcac agcttgtctg gagagcatat atagaacaag gtattgattt
     2881 agataaggat ggcggaaatg ctgttttacc aactgattta gttaccgata agattgatat
     2941 taattggaga actaattatt agctaattca ttataatatg aatcacaaat atagattttt
     3001 tagacacttg tgattctata tataagtttc ttaaaaaaca aaccacttaa tagtatgaat
     3061 tgattatgta tcaatattaa tattgacgta attttatttt aacctataat gtggtttatt
     3121 taaggttaaa attaatatgg ggagataaat gatgtataag aataaaaaaa tatatttcct
     3181 tttatctgta attataataa tgatattgag tttaagtttt gtattattac ataatagaga
     3241 attaaaaaac atatgcctta tatattctga ttccattgaa gaagatagtg aaattgtata
     3301 tttagatagg aatttcacta taaaaaagaa tatacaaata cctgcaaggg atatagtaac
     3361 aagttgtaat aagaaagata cagtattgtt gccaacgtta tcagataata aattatttga
     3421 agttgataaa gatggaattg ttaaatcatc ggaaactgat tttggaggga attacataag
     3481 gtgtaagaac aatgaagaat taattctata taatgtatcc ctagaatata atagaattaa
     3541 ttttataagt tcagattctc agaaaaagtc gttagatata aaagaatcat tgcttttgtc
     3601 tggtgatttt gatgatgaaa atgtatatat attaggttat aaatttgatc aaaataaaga
     3661 aggagataca tttctgttta ttatagataa aaatgatttt aaaataaaag atcaaattaa
     3721 attaatgaaa aacatgcgaa tatatgatac ttcattaatt gatggtaaac tttttattgg
     3781 cgtagatagc aaagtagatt atttattata ttatgatgtg aaaaaatcta ctttaaataa
     3841 aattgaatat aaagagtata ttaaagatgg tataatggat actaaaaaga ttctgtataa
     3901 tgataaatat attttttact tatttttaga tggtaatata ttgaaattaa ataggaaaga
     3961 tttaaatatt ataaaaaata ttaagctaaa taataaaata attttgagtg gttgtttaga
     4021 taaaaatcag ctatattctt taagcgtaga catcaataaa aataatcaaa taggtttagt
     4081 cgacgtcttt gatattgata agcttaataa tataaataat ttttcagttg gtccaataag
     4141 aaatacaact ccaagagata tatttatact acaataataa ttaaaggagt tataatttat
     4201 gaagaaaata cttacaatca tagcaccaag tatattgaca tatacatata tatttataga
     4261 ttctcatttt ccatatagta aatggatttt aataggaatt tatattttat ttcctattat
     4321 gtttattgct caaactatta tttcttttgg atcaataaaa aatatgttaa ttggatttct
     4381 attattgtca ctatcaatca tagtgcctat taatgaatgg tataaagtgg gtagcatgat
     4441 tgtacctata ataatttact cgtcattagg tataataaca tttttcttat caaagacaat
     4501 aaatactgtt aaaagaaaat ggaaaaaata aatctaatat aaagttttaa gattcaactg
     4561 atggaaagaa ttaattggaa cttaaggtag aatatccagt tatttttatt attttcaaaa
     4621 atcaaaagca tatgaactat aaagaatttg taaatgcaat tatgttaata gataatctgt
     4681 gtggaatata ttggcattta ttgaagatca atgaattgga ttggataaat aaaagaagta
     4741 cttagggttg caaaagaaag catagaagaa ggtattataa aagcattaaa acggataaaa
     4801 aatgacaaat agaacatata attgtgtaac tatatgttct atttctttat gcaaagcaca
     4861 ttttgagtat ttaatcattc ctttattaag atataatatt ttaagcagct tgaacttttg
     4921 attcattatc attttctatt tcaatttttt cttttttact ttctacaata tctctaataa
     4981 ccttaaatat ttgtattatt aaagttggaa gaaaagcaaa taaatgaact gataataatt
     5041 cgctagtagc aagtggagtt atttcaaata agccttgaag tccaggtata agtaagactg
     5101 cattcacaag aataacacct actataaaag caatccaact gaatgtatta ttgaatactc
     5161 caagtgagaa tattgatttt ctaccacggc aattaaatcc atggaacagt cttgctaaac
     5221 ataatgtact aaatgccata gtcatagcta gtccgtcaga acccttagta agtcctatgt
     5281 gatatgaaat catagtaaat atacctataa gtaaaccttg aatgcaaaca tcttttatga
     5341 aatcttgtga caatatggat tcattagcat ctctaggctt atctctcaag acatcttttt
     5401 tagatttttc cattcctatt gcaattgcag gtagactatc tgttaaaagg ttaataaata
     5461 atagatgtac tgcagcaaat ggaactggta aagcaaacaa tgatgaataa agtactgcca
     5521 gtattccaga catattacct gaaagtaaga attttattga attttttata ttagcatata
     5581 tatttcttcc gttagtaaca gatttaacaa tagtagcaaa attatcatct gttaaaatca
     5641 ttgatgcggc atcttttgat acttctgttc ctgttattcc cattgcaatt ccaatatcag
     5701 cttgttttaa agctggagca tcattaacac catcaccagt catagcaacg attttcccct
     5761 tgttttgcca tgctttgact attcttattt tgtgttctgg ggatactcgg gcataaaccg
     5821 aaatatgttc taatttagaa aaaagttcat tatcagacat tttatcaagt tctaatcctt
     5881 caacagctaa atcatcttct tgtaatattc cgatttcttt agcaatagca gaagctgtaa
     5941 tcttatgatc accagtaatc ataactggtt taatagacgc ttttaaacaa tctgtaacgg
     6001 ctgatttaga ttcttctctt gggggatcaa tcattgaaat taatcctagg aaagtaaagc
     6061 cattttcatc ttctaaatca atatttttat tttcattaag ttctttgtaa gcaaaagcca
     6121 aaactcttaa tccttgagag gaaagttttt tgttaatatt atttatatga gttttatctt
     6181 cattagtaaa tctttttaat ccatgtatag tttttatcga agttactctg tctaataata
     6241 catcaagagc acctttggtt atcattgtag atttcccgtc tattttatga agagtactca
     6301 taagttttct atcagaatca aaaggaattt cacttaatct agaatgattt tttctacaat
     6361 caatttcact tattgaataa tcatgaccta agttcactaa agcaacttca gtgggatccc
     6421 caatttcatt tccatctata gaagttgaat cattacaaag tatagaactg gttaaaagaa
     6481 aatgtgctat aggatttttt aaatcaattt cattagcatt aactaattta ttatcaacaa
     6541 aaattttttt gacagtcatt ttgttttgag ttaatgtacc agttttatca gaacaaataa
     6601 cagatacaca gcctaatcct tcaacagctt taagtttttt tataattgca ttttcttttg
     6661 ccatagattg agttccaata gctagtacaa ttgtaactat agaactaaga gcttctggaa
     6721 ttgcagcaac agcgagagca acagcaaaca ttaaggaatc aagaacgttt gtccctctat
     6781 ataagcttaa tccaaataca agaatacaga ttccaatgat tgcaagagct aatttcttag
     6841 aaaaagcatc taaggaagct tgaagaggtg tacttttttc ctgagtttct tccattaggg
     6901 tagctatctt gccaagctct gtattcatac cagtattagt tacaaggaca gtagctctgc
     6961 cgtatgtaac tagtgaacta gaaaaaacca tgttcttctg atcacctaaa gcaacttcgt
     7021 ctttatcaat tacataagaa attttatcaa cactttcaga ttcaccagtt aatgaacttt
     7081 cattaacctt aagagagaag ttttctaaaa ttctaccatc agctacaact aaatcaccag
     7141 cttctaatat taaaatatct ccaggaacaa cagattttga aggaatttca actttaattc
     7201 cttcacggat aacttttgca ttaggcgagg ttaatgattt taagctagct aaagattgtt
     7261 cagctttaat atattggaca gtacctaaaa tagagttaat agttataaca gccaaaatta
     7321 ctatagtact ttcgatatta ccagttgcca tagaaataac agcagcaata attaagataa
     7381 ttactaacaa atctttaaac tgatcaataa atacagaaag tgtactcttt ttctttcttt
     7441 catttaaaac gttctctcca actgattcta gtaactcacg tgctttttta ttcgtcagtc
     7501 cattagtagt tacatcaaat tcttttagtg aatctttgat atttttagaa aagaaatttt
     7561 tcatattaat ccatcctttc gtgttataag gtacgtgaaa ataaataata aaaaaagacc
     7621 tttaatataa cttcaaattt ttgaagttat attaaaagtc tcgttaccac ttgggtatat
     7681 aacaccagaa tacaaatagt aaacgcggtt gttgatgtta tatttataac tactcccctt
     7741 taatataaaa caagtatttg tattaaatat agtataaaaa aagaaagaag tcaatgaatt
     7801 ggatgtatat ttttaaatta aatatatttt atttatgata aaatatattt aaatatagta
     7861 attagatata atacaagaat aaattaaagg tgggttgtaa ttatgactgg attagtatta
     7921 gaaggaggag catttagagg attatttaca gctggtgtat tagatgcatt gctagatata
     7981 aaagcagaaa taaagtatgt aataggggta tcggctgggg ctactaatgc ttattcatat
     8041 atatctaagc aaaaaggaag aaatttagaa ataatggaga gatttattaa tcataaaaga
     8101 tatgttggat atggtaattt gataaaatca aaggcaatta tggatttaga ttttgtgttt
     8161 gatgaaattc ctaataaata ttgcattttt gattataaga ctttttcaaa ttatgatgga
     8221 aagatgcttg tgggagctct taatattgaa actggagaat cggaatattt tgataaagat
     8281 gaattggatg ataagaattc tattttaaga gcaacttgtg caataccaat gttatttcca
     8341 tttgctaaaa taaagaatag ttattatgca gatggaggtc tattagatgc aattccaatt
     8401 aaaaaatcaa tagaagatgg taatgataaa aacataattg ttttaacaag aaatgaagga
     8461 tatagaaaga aacaatcaaa agctaataaa ttcacatata agttttataa aaataaatat
     8521 ccaaagttag ctaatgtgct taaaaataga tatattcaat ataataagca gcttgattat
     8581 tgtaaggagt tagaggaaaa taaaaaggca attattataa gaccaactat aaaaatggat
     8641 ataggaagat ttgaaagaaa caaaaataag ttaaaggcaa tatatcaaaa tggatatgat
     8701 ttagttataa gagataaaga taaaattctt tattacttga agtaagcatt acatgattat
     8761 gaaatatata ttaaaaataa tttattgagt ataatagaat taaatttagt aaggtaagta
     8821 gaagggataa gtaaatatgt tgacgaatat taagacacca aaagtttatg atcaagttat
     8881 agaggaaatt aaaaataaga taaaaaacgg tgagataaaa aaaggtgata aattaccatc
     8941 agaaagagaa atggcagagt cacttggtgt ttcacgtaca tctgttagag aagcattaag
     9001 agcacttgaa gtaataggcc tagttgaaag tagacaagga gcaggaaatt atataagaac
     9061 taattttaac aattccttat ttgaacctct ttcaattatg tttatgttac aagagagttc
     9121 acctaaagag atgtatgatt taagagaaac attagaatta caatgcgcta aactatcagc
     9181 taaaaatata gaagacaatg agcttgagct tttaactgca atattagaca gaatgtatgt
     9241 tgcagaaagt gaagaagaaa gtcttgaatt ggatattaag tttcactatt tacttgcaaa
     9301 gacatcaagg aatgtattgc taataaatgt tgttgaagtc atatcacaac ttatggacga
     9361 gttcattaag aaatctagaa tgcaaatttt acatgaagga aatactaggg agaatttgtt
     9421 agatatacat gaaaatttag tcagagcttt aaaatgtaga gatgaattga aagtttcaag
     9481 tgctatgaaa gagcattttg atttaatcag aaaagcctac ggatattaaa aataaatctg
     9541 tctttataaa ttaaaatact ggtaagcaac tatacaattt aaatagttgt ttaccagtat
     9601 ttttttgtta tcttttaaac aatgtattaa caagttatgt cttaaaattt ttaatttaaa
     9661 tttttttgaa attaattata ttaaataatt taataataaa tatagtaaat ataatgattt
     9721 acaatgaaaa acttatacaa acgttgcttg ataaaaaaat aacaattgtt tacaagggat
     9781 attttgggta ttataattaa tcttgtaagt ggtcatacca atttgcaatt ggtatgacat
     9841 gttatccgag taatgagata aaagtgtagt tattattttt tatcttgtat tttttcaatt
     9901 ttaaaagttt gattattcta aattgtttta gcagggttaa atattatttt ttgcagagca
     9961 atattggtat taaaaaatac aattttagga ggaagatata atgaatattt tagtttgcat
    10021 taaacaggta ccaggaactt ctaaagtaga ggttgaccca gttacaggag tgttaaagag
    10081 agatggaata gattctaaaa tgaatccata tgatttatac gcattagaaa cagcatttaa
    10141 gattagggag agcaaaggtg gtaatgttaa ggttttaagt atgggtccta accaagcatt
    10201 aagtgtaatt aaagaagcat atacaatggg tgctgatgaa ggcacattat tatcagatag
    10261 aaagttcgga ggagcagatg ttttagcgac atcatataca atagcgcaag gtgtaaagaa
    10321 gatgggagat tttgaactta taatttgtgg aaaacaaact acagatggag acactgctca
    10381 agttggatct gaaatggcag agtggttaaa catacctcat gtagctaatg ttaaaagtat
    10441 agttgaagta ggagattcat caattacggt tgaaatggac atgcctgaaa gtattgagac
    10501 agtaaaaata gcatatccat gtttaattac tgttgataag ggaatatttg aaccaagatt
    10561 accttcttat aaaaagaaat tatcaacaaa agatagagat attaaaatat taagtcttaa
    10621 tgattttgat gataatgatg aaaaacatta tggacttaat ggttcaccta ctcaggtaga
    10681 aagaatattt ccaccagaag ttaataatga tagagaaatg tggacaggta gttcaggtga
    10741 attaagtgga agaatagaga aaaaattaaa ggaattaaaa tttatttagg tatttagata
    10801 attaatgcgt tggtcctatg aaaattaaaa aggaggaaga aaatatggca aagttagttg
    10861 taaatcaaga aaagatatca aatattgaag agttaataaa aatatgtcct tttggtgctc
    10921 ttgaaaatca taatggtata gttgaaataa gtggagcatg taagatgtgt aggctttgtg
    10981 ttaaaaaagg acctaagggt gcagttgaat atatagaaga ggaaattaag aaaatagata
    11041 aaagtctttg gaatggaatt ggagtttatg ttgatcatgt aaatggtgaa attcatcctg
    11101 tcacttatga gcttataggt aaggcaaaag aattagcaag taagataaat caacaagttt
    11161 atgccgtatt tattggaagt aatattgctt ctaaagctga agaaatactg cattatggcg
    11221 tagataaggt gtttgtatat gatgatgatg aactaaagta ttttagaata gaaccatata
    11281 cagcagcatt tggagatttt ataaacaatg ttaagccaac agccatatta gtaggggcaa
    11341 caactatagg caggtcgctt gcaccaagaa tagctgcaag atttaaaact ggacttacag
    11401 ccgattgtac aatattagat ataaaagaaa atacagattt agttcaaatt agaccggcat
    11461 ttggaggtaa tataatggct caaatagtta ccccaaattc aagaccgcaa ctagcaacag
    11521 tcagatataa agttatgaca gcaccaaaaa gaagcgaaaa agttacaggc gagatagtta
    11581 actgcaaaat agaaaaagga aaattaagat caggtatcac agctcttaat ataaagaaaa
    11641 aagatacaga ggttggaata agtgatgcag aagtaattgt agcagcagga agaggcatta
    11701 aatcagaaaa agatttagaa ttagtgaaac aattagcaaa agttttggga gcagaatttg
    11761 catgtactag accattaatt gaagcaggct gggttgatgc gaaacgacaa atagggttga
    11821 gtggaagaac cgtaaggcca agacttatta taacttgtgg aatatctgga gcagttcaat
    11881 ttactgcagg aatgaataat tcagattata tatttgctat aaatactgat gaaaaagcac
    11941 caatatttga agctgctcat tatggagttg ttggtgatat atatgaagta attccacaac
    12001 ttatagaaaa aataaaaatg gctaaggagg catagattat ggattacaaa gaagttgaat
    12061 taaaggacta tgaatatata ttatcagtta caggaaatga tagagaaaga gtttttttta
    12121 aagatggaat aaatgaggat tatagccatg atgaattagg tggaataaga caaatgcctg
    12181 atgtagtagt tcaagctatt agtacagaag aagtttcaag tgtaatgaaa tatgcttatg
    12241 aaaataatat tcctgtaact ccaaggggat cagggacagg actggttgga gcagcagttc
    12301 cacttaaggg cggaatagtt atagatctta gcaaaatgaa taaaatatta gaattagatg
    12361 aggaaaatct tactttaaca ttggagtcag gcgtattgct aatggaaata ggcaaatatg
    12421 ttgagcaatt tgatttattc tatccaccag atccaggtga aaaatcagca acaattggtg
    12481 gtaatataaa cactaatgca ggtggaatga gagctgtaaa atatggagtg actagggatt
    12541 atgtaagggg attagaagta gtactcccaa atggagaggt agtaaactta ggcggaaaag
    12601 tagttaaaaa tagttctgga tattcattaa aagatttaat tattggttct gaaggaactt
    12661 taggaatagt gacaaaggca attttaagat tgcttccact tcctaaaaaa gcagtgagtc
    12721 tacttattcc atttgaaagc cttgaaagag caatagaaac tgtaccaaaa ataataaaat
    12781 ctaaatcaat accaacagca attgagttta tgcaaagaga agcaatatta gctgcagaag
    12841 aatttttagg aaagagcttc cctgataaat cttcagatgc atatcttcta ttaacttttg
    12901 atgggaattc tatagaggag atcgagaagg attatgagaa tgttgctaat atttgtttgg
    12961 aatgtggagc attagatgta tttatttctg atacagaaga aagacaagag tcaatctggt
    13021 cagcaagagg atgtttcctt gaagctatta aagcattaac aactgaaatg gatgaggttg
    13081 atgttgttgt accaagaaat aaaattggag attttgtaac ttttactcat gaacttgaat
    13141 gtaaatcaaa tataagaata aagagttttg gccatgctgg agatggaaat ctacatgtat
    13201 atatattgag agatgaatta gatgaagaat catggcatac aaagttaagt gaagttatgc
    13261 aaattatgta tgacaaggct aaagaattac aaggtcaagt ttctggagaa catggtatag
    13321 ggtttgctaa gaagggatat ttaaagcaat cacttccaaa tgaatgtatt gatataatgg
    13381 aaagaataaa attagccttc gatcctaaaa atatattgaa tccaggaaaa gtatgtgaat
    13441 agaattatat ttttaaatat cttatttatc cataaagcta agtttttgtt tacaattata
    13501 aattaatatt ataaaataaa aggaaaagta agagattatg ctctggtaac cgtctaggtc
    13561 cagggctttt tatttgtaag tgtattttaa atgaaaaagg agacatgtag cattgaaaga
    13621 gcaggataaa gaattaacat cgaaagtgat tgaatttgat aagaaagaaa cgcatcaatg
    13681 tggaatttgt ggcgaggatg caatttgttt taatacagat aataatattt ggctgtgtga
    13741 aaagtgtaat gatatacaag atggtatgga taagtttgca gagaagatgg agaaaaagtt
    13801 aagcaaaaga gtatattctt ttgatataaa tgaattatta aattgtttat ctaaagatga
    13861 aatatataat atagctagaa atcttggtgc taataaaatt tccaatttag ctaaaggaaa
    13921 attaatagaa aaattaaatt cagaatataa agctttaata gaacaaagac tttatttatt
    13981 tgaagaggaa agatataaaa ttttaaagag ttatgttgat aatgaaggta taaaaaactt
    14041 tgatgatatt gacgaagaag aggcaaataa gagtgcatat tttattcaac aaggatttct
    14101 ttttccaaca gtaaaagatg aagaatcgtt atttttaatg cctaaattag ttcaagattt
    14161 agttaaagag aagaataata ttgaatatag acgtctatta aaaaataatg gtgaaataat
    14221 aaacatttat agaggaatga atcaagcata tggtatttta gaaattgagg ctagtaaaaa
    14281 aatattagct agatatcaaa atatagaaaa attacaatta gaagatttac ttagagaagc
    14341 agcatattat tataatgagt acagagaaga aggaaaattg tttgtaaata atcaaataga
    14401 agattatgaa gggtttgttg atgaaataaa tgcaaacaaa gatttggaat atgtacatat
    14461 atcaaaagaa gaattattaa atatgtcgga agaaaattgg gtgtacaaca ccaaggcagg
    14521 aaaatcattt tataaagaat ttactagtat gtttagtgta gataaagaca tgacaatagc
    14581 gatgatggaa gatttagctt tggatattca agataatgaa ccaaagaaag ctgttgatca
    14641 aatgctagaa ttaataaata tagaaaatga acaagttaga tttgtagcag ctggcatgat
    14701 gactaaattt gtaaataaac ttggactttg gaaatacaaa ggtgcttcaa ttaatgatat
    14761 gaaagcaagt gagataagtt caaaacagaa taagcctata ggcagaaatg atttatgcat
    14821 atgtggaagt ggaaagaagt ataagaaatg ttgcggaaga aatggtaatg ttattccaat
    14881 ggcttaatta aaatatattt atacatattg atttatttaa tagttgagga tagaacaagg
    14941 aaataataga atagtatgat ttttgtttta tattcttgat ttattatttc cttttatatg
    15001 attaaattga tttttcacca ataaagatat ttcaacatat aatgaattaa atcattacat
    15061 ggagttgaaa atacgtgata tacgggctta ttttagctgg aggtaaaggc agtaggctat
    15121 atcctctatc aagagccgat caaccaaaac aatttttaaa gataattaac gataaaagct
    15181 ttttggtgaa tacagttgag aggataacac cactaataga taaaaataat atttatgttg
    15241 tgactaatat ggactataga gataaaatta aagaagaact acagggaatt aaagacgata
    15301 aagtttttgt agaacctgct aataaagaaa ctgctacttg tataggatta tctgcaataa
    15361 agctattaaa acaagatgct aatgcagtta tggttgtatt accatcagat cattatattc
    15421 aaggtgagaa aaattatata gacaccttat ctcaaggaat tgagatagca aatagaagaa
    15481 ggtgtattgt tactttagga attgaaccca caagacctga aactggatat ggttatattg
    15541 aaatgggtga aagatctagt ggcaatatac caacttatcg agtagctcgt tttaccgaaa
    15601 aacctaactt agaggttgcg aaagatttta tattaaaggg aacgtattta tggaattctg
    15661 gaatgtttat atttagagcg gatgttattt taagagaaat agaaaaatat cttcctaaat
    15721 tatacaaacc attaatggag atatataaaa gcttaggtga agaaaatgaa gaagaagtca
    15781 taaaggaaca atatgaactt atagatggaa tatctattga ttttggagtt atgcaaaaga
    15841 ctagaaaagc atatgttata aaatgtgatt ttagctggga tgatatgggt agttttggag
    15901 cattaagtag attgcttggc aattattcaa ataataataa tatatcaaaa aatgtttata
    15961 ttgatgaatg tgagaattgc tcaatatttg gaaataagaa tttaataatt ggatttggga
    16021 taaaggatct agtagtggtt gatgctggcg acgtaatact cgtaatggat aaaaataaag
    16081 atcaagaaat taagcattta ttaaataagc ttagtgaaga aaatgaatat agtaagtttt
    16141 tatgatataa cgaaaatatc aatataacta ttaaggtata ttgatatttt gttatttaaa
    16201 aaattgatga ttgatatgaa attaattttt aataattaat ctcatatctt tttgtttgtg
    16261 tataaatatc agatgaagtg gaacttaata ttattaatgg aaaattgtta tttgataata
    16321 tattaaaggt taattaaaat ttttaaatta ttattaaata caagataagt gtgttgtaaa
    16381 aatgagcgtg cagtattatt attagagcag agcataaaaa ataatattta aaattaagag
    16441 tattgtttta tatgagagtt tagaaaaata agtgtagagg atgtggtcac gctttgatga
    16501 tgaatactca cagaattatg ggtgagaata ttataaaata tgctaataca aagagtattt
    16561 atttaattaa caataagaga tttatatggg gaaatataaa accagattgt gttcctaaat
    16621 atacttttat gaaacattat tttaatgaaa gtatagatat ggtagttgat aaaataatat
    16681 atttatcatc attgacatta gaagacgttt attacaaaat tactattgga agatttagtg
    16741 aggaacttgg tgtgatttgt cacttcttat gtgattattt ttgtgcacca cattattata
    16801 gatgggagtt caagagtact agtgcagtga agcatcacat gatgtatgaa caaaggctag
    16861 caaagttaac taagaaattc aagccgattg gtattataaa tacaaatgtt aagccacaga
    16921 atataaaaga atttataatt cagttacaaa aacagtatga tggaatgctt gattataaaa
    16981 atgatttaac tttttcgtat tatatttgcg atagtgtgtt aaatatgatt ttagataatg
    17041 tattttctaa tgaaaataaa gtgaatagag caatttgatt tttattaggc atattgactt
    17101 gttatttttt gattatgcct taatacagaa aactcgtctt ttagttcaag gcgagttttt
    17161 ttatgtttca ataattagta atttacgagt aagtaataat ttattgaaag gaattgttta
    17221 agttttcaga attgggggta ccttttctta gttagatatt aagtatattt tatagtatat
    17281 gcgttaatta tataaaataa tcagttaaat gtaagataaa tgaatagtag ataataattg
    17341 gacagagaat atttattcta aaattacgaa tactttaaaa gaagttgaca tcaaaaaaaa
    17401 caataagtat actaaaaaaa tatgtttaaa ataatacaaa tttagattat ataaaagaat
    17461 gaaatgagga tgagaaggat gtctgtttta tcacttatat taacagctat tgggttatct
    17521 atggatgctt ttgcagtatc tttaactaca ggatttaaaa tatccaaaga tgatagaagt
    17581 aagatagctt taaaagctgg tatgtacttt ggaggatttc aagcattaat gccactaata
    17641 ggatggatat taggagttaa atttactaaa tatatacaaa gtgtagatca ttggattgct
    17701 tttgttttac ttacggtaat tggtggaaaa atgatatttg acggtctaaa aggagaagag
    17761 gataatgaat ttgaagatgt acattctaat aaaaagtttt tacttttagc tatagctaca
    17821 agtattgatg cattagcagt tggagttact tttgcgtttt taggaataaa tataataaag
    17881 tctattacaa taataggagt agttacattt attttaagta taatagctgt atatattggt
    17941 aaagtattgg gaaataaatt aacaaataag tctagcattg ttggtggagc aattttaata
    18001 ttcataggac ttgaaatttt agtcgaacat ttaggtttat tcgctaaata atttgaataa
    18061 gtttgacata cgtacataaa aatatgatag aatcataatg tataacaatt taaggttaat
    18121 ttatattgtt tctaaacaaa atttatattt ataagatttt attttgcatt agaaattaaa
    18181 ctaatgggga ccaataaagt aaatatttat taatttaata atttataaat tttatgctaa
    18241 aataaaatta ttgaaatttg agaatcatac agaaataaat ttatataata attatgagat
    18301 tgttaaaaaa aatactaatt gtaataagga gaagtagaat ggagaaaaac aaaaatatat
    18361 ctatggcagt tattaaaaga ttgccgaaat attacagata tcttggtgaa cttatgagca
    18421 atgatgtaga taggatttca tctaaggaat taggtgagaa aataggattc actgcatctc
    18481 aaattcgtca agatttaaat tgctttggtg attttggtca acaaggatat ggatacaatg
    18541 taaaagaact gtatagccaa attagtacaa tattagggct agatagaggt tatgaagcag
    18601 ctttagtagg agcaggaaac ataggtcaag cagtttcaaa ttactctaga tttgaaaatt
    18661 taggttttaa aataacatgt atatttgatg caaatcctaa gttgattggt atgaaaatta
    18721 gagatgtaga gataaaagat atcgatgaaa tggaagcaac tttacaatca caaaagattg
    18781 atataggcat aatttgtgta cctagaaaga atgcccaaaa tgttgcagat gaattaatta
    18841 agggtggagt aagagcaatt tggaactttg ctcctgttga tttaatagtt ccacaaaatg
    18901 ttaaagtgga aaatgtacat ttaagtgaaa gcttattgac tttaatttat ttattaaatg
    18961 aaagtgattc ttagagaata ttttaacaat aattttaaaa atactgttaa aatttaacgt
    19021 attgtggtat gcatatacag attagattat gcatatatta tatttgcata taaataggtg
    19081 ataatatatt attttaaata atatattatc acctatttta aataatattt atgaaaaaga
    19141 tttaagataa gataatttag ttattattat ctcttttaaa gatatagata aatatgttct
    19201 gttatagcaa tatgctttat tgttacgaat aagaaataaa atgatttaag attgcttttt
    19261 aaatgtttaa aattaaatga attacttaaa ttagtataaa atttaggtaa aatattataa
    19321 taatgcacaa tattttattg caaataatta aagtaagtat tataatttta attgaagcaa
    19381 gatgcttcat tatttttaga ttcatttgtt ataatattaa caaatgaatt aaaaaatgtt
    19441 tgaaatagta agaaaattaa aaaaataaat aagcaagttt aagggaggat cttaatatgg
    19501 aattaaaaaa tgtgattctt gaaaaagaag gacatttagc tattgttaca atcaatagac
    19561 caaaggcttt aaatgcatta aattcagaaa cattaaaaga tttagatact gttatagaag
    19621 atctagaaaa agacagcaat gtatattctg ttatcttaac aggtgctgga gaaaaatctt
    19681 ttgttgcagg agcagatatt tcagaaatga aagatcttaa tgaacaacaa ggtaaagaat
    19741 tcggaatatt aggaaataat gtattcagaa gattagaaaa attggataag ccagttatag
    19801 cagctatatc aggattcgct cttggtggtg gatgtgaact tgctatgtca tgtgatataa
    19861 gaatagcttc agaaaaggct aagtttggtc aaccagaagc tggtcttgga ataactcctg
    19921 gatttggtgg aactcaaaga ttagctagaa tagttggtct tggtaaagct aaggaaatga
    19981 tttatacttg cgatattatt aaagctgaag aagcttatag aataggttta gtaaataaga
    20041 tagttccatt agaaaactta atggatgaag caaaagcaat ggctaataag attatggcta
    20101 atgctccaaa ggcagttaag tattgtaagg atgctatcaa cagaggtatg caagttgata
    20161 tagatgcagc aattttaata gaagcagaag actttggtaa gtgttttgca acagaagatc
    20221 aaactgaagg aatgactgca ttcttagaaa gaagaacaga aaagaatttc caaaataaat
    20281 aatttaaatt aagtttaaaa atctattagg gatttatata gttttgttta tcaataggtt
    20341 taattaacaa ggagggtaat ttaatgaatt ttaagttaac tagagaacaa gaattagtac
    20401 aacaaatggt tagagaattt gcagtaaatg aagttaaacc aatagctgct gaaatcgacg
    20461 aaacagaaca atttccaatg gaaaatgtta aaaaaatggc tgaattagga atgatgggta
    20521 ttccattttc taaagaagta ggaggagctg gcggagatgt tctttcttat ataatagctg
    20581 tagaagaatt atcaaaagtg tgtggtacta caggtgttat actttcagca catacatcat
    20641 tatgtgcatc agtaattaat gaacatggta ctccagctca aaaagaaaaa tatttagcag
    20701 atctttgtag cgggaagaaa attggtgctt ttggtttaac tgaaccaggt gctggtacag
    20761 atgctgctgg acaacaaaca acagcaacat tagaaggaga tcattatgta ttaaatggtt
    20821 caaaaatatt cataacaaat ggtggagttg ctgaaacttt cataattttt gctatgactg
    20881 ataagagcca aggaactaga ggtatttctg catttgtagt agaaaaatca ttcccaggat
    20941 tctcagtagg aaaattagaa aacaagatgg gtatcagagc atcttcaact actgaattag
    21001 ttatggaaaa ctgtatagtg ccaaaagaaa acttacttgg taaagaaggt aaaggatttg
    21061 gtatagcaat gaagactctt gatggaggaa gaattggtat agctgctcaa gctttaggta
    21121 ttgcagaagg agcttttgaa gaagcagtta actatatgaa agaaagaaaa caattcggaa
    21181 aaccactttc agcattccaa ggattacaat ggtatattgc tgaaatggac gttaagatag
    21241 aagctgctaa gcatttagta tataaagcag catgtaagaa acaagcaggt caaccttatt
    21301 cagttgatgc ggctagagct aagttgtttg cagcagacgt tgcaatggaa gttacaacta
    21361 aggcagtaca aatctttggt ggatatggtt acactaagga atacccagta gaaagaatga
    21421 tgagagatgc taagataact gaaatctatg aaggaacttc agaagttcaa aagatggtta
    21481 tcgcaggaag cattttaaga tagggaggat tttataatga atatagtagt ttgtgtaaaa
    21541 caggttccag atactacagc agtaaaaata gatcctaaga ctggtacatt aattagagat
    21601 ggtgttccat caattatgaa tccagaggat aagcatgcat tagaaggagc attacaatta
    21661 aaagagacta tgggtgcaaa agttacagtt attagcatgg gtcttccaat ggctaaagcg
    21721 actttaagag aagcactttg tatgggagct gatgaagcta tccttttaac agatagagca
    21781 cttggaggag cagatacttt agctacttca aaggcattag ctggagtaat aaaaacatta
    21841 gattatgata tagtatttgc aggaagacaa gcaatcgatg gagatactgc acaagtagga
    21901 ccagaaatag ctgaacattt aaatattcct caagtaactt atgttcaaga tgttaaagta
    21961 gaaggaagtt cattaatagt aaatagagca ttagaagatg gacatcaagt tgtagaagtt
    22021 aaaactccat gtctattaac tgcaatcgaa gaattaaaca aaccaagata catgaatgtt
    22081 gggaatatat tcacaactaa cgatgatcaa atcaaggtta tgactgcaga tgatatagat
    22141 gtagataaag ctgaattagg acttaaaggt tcacctacaa aggttaagaa gtcaatgact
    22201 aaagaagtta agggcgcagg agaacttgta aaagaatcag ctaaagaatc agttagttat
    22261 gttttcggaa aattaaaaga aaaacactac atctaagata ataggagggt aatttattat
    22321 gaatatagca gattacaaag gcgtttgggt ctttgctgaa caaagagaag gcgaattaca
    22381 aaaagtatct ttagaactac ttggagaagg tagaagagtt gctgataaat taggagtaaa
    22441 gttaacagct ttattactag gaagcaatgt agaaggatta tcaaagacat tagcagaaca
    22501 tggtgcagat gaagttttgg ttgcagataa taaagactta caacactata ctactgatgc
    22561 atatacaaaa gttatttgtg atttagcaaa tgaaagaaag ccaggaatat tatttgttgg
    22621 agctactttc ataggtagag atttaggtcc tagagttgca gctagattaa atactggact
    22681 tacagctgac tgtacatcaa tcgatgttga agttgaaaat ggtgatttat tagctacaag
    22741 accagcattt ggtggtaact taatggcaac aatcgcttgt ccagaacaca gaccacaaat
    22801 ggctacagta agaccaggag ttttcgaaaa agttaacact gatggagcta actgtaaagt
    22861 agaaaaagtt gaagttaagt taactaataa tgatcttaga actaaagttt tagaaatcat
    22921 taagagcaaa aaggatatcg tagatatctc agaagctaag attatagtag ctggtggtag
    22981 aggagtaggt tctaaagaaa acttcgaatt actaggagaa ttagcaaaag ttttaggtgg
    23041 aactgttgca ggttcaagag ctgctgttga aaaaggatgg atagaaaatg cttaccaagt
    23101 tggtcaaact ggtaaaactg ttaaaccatc aatatatata gcttgtggta tttcaggagc
    23161 tatccaacac gttgctggta tgcaagattc tgatatgatc atagctataa ataaagatga
    23221 aactgcacca ataatgaaag ttgcagacta tggtatagtt ggagacgtta agaatgtttt
    23281 acctgaatta attgctcaag ctaaagaaat aataagtgct gaataatttc agttttaata
    23341 atatattatt ttctatttga aaagaaaaag ttaataatat aacaatataa ataattaatt
    23401 aacaagatta ataatttttt aacaagttga ttgtttaatc cttagttaaa gtaatgctat
    23461 tttaactaag gatatctata aagaaatgat tttgaggagg atttatctat ggaaaagatt
    23521 tttgtacttg gagcaggaac tatgggtgct ggtattgttc aagcattcgc acaaaaaggt
    23581 tatgaagtaa tcgtaagaga tattaaagat gaatttgttg aaagaggaat tgctggaatc
    23641 aacaaaggat taactaagca agttgctaag ggaaaaatga ctgaagaaga taaggaagca
    23701 atactttcta gaatttcagg aacaactgat atgaaattag ctgctgattg cgatttagta
    23761 gttgaagctg caattgaaaa tatgaaaatt aaaaaagaaa tttttgctga attagatggc
    23821 atttgtaaag aatcaactat tttagcttca aacacttcat cattatcaat aacagaagtt
    23881 gcttcagcaa caaagagacc tgataaagtt atcggaatgc atttctttaa cccagctcca
    23941 gtaatgaagc ttgttgaaat tataagggga atagctactt cacaagaaac ttttgatgct
    24001 gttaaacaat tgtcagtagc aatcggaaaa gaaccagtag aagttgcaga agctccagga
    24061 tttgttgtaa acagaatctt aatcccaatg attaatgaag ctacattcat ttatcaagaa
    24121 ggaattgctt cagttgaaga tatcgatgca gctatgaaat atggtgctaa tcacccaatg
    24181 ggacctttag ctttaggaga tcttattgga ttagatgttt gtctagctat catggatgtt
    24241 ttatttaatg aaacaggaga cagcaagtac agagctagca gcattttaag aaaatatgtt
    24301 agagctggat ggcttggaag aaaatcagga aaaggattct atgattattc aaaataatta
    24361 tatgattgct taaggtacat gtgagaaaat aataaacaaa agatattaga catattttat
    24421 cagtgtaaga gaatgatttc actaatagta gaagttctat taggtgaaat tgttagcgaa
    24481 gtattggata aaatagacaa atataataat ttattatttt attgagtgtg tctaagttta
    24541 aatatgaatt actgggactc tcaaggtttg ataactttga gagttttttg tctattaagt
    24601 aaggtataaa atctaaaaat attaaaatgt agttttattt acaaaaataa gaaggaaaat
    24661 aaagttattt gtagaaatat ataatatatg aagaaaagta tatttttagg aggtatagat
    24721 ttatgatgag atttacatta ccaagagata tttattatgg aaaaggatca ctagaacaac
    24781 taaaaaatct taaaggtaaa aaggcaatgc tagtacttgg tggcggttcg atgaaaagat
    24841 ttggatttgt cgataaggtg ttaggatact taaaggaagc tggaatagaa gtaaaattaa
    24901 tagaaggagt tgaaccagac ccatcagttg aaacagtgtt caagggcgct gagttaatga
    24961 gacaatttga accagattgg attatagcta tgggtggtgg atcaccaatt gatgctgcaa
    25021 aagcaatgtg gattttttat gaacacccag aaaaaacttt tgatgacatt aaagatccgt
    25081 ttacagtacc agaattaaga aataaggcta agttcctagc gattccatca acaagtggta
    25141 cagcaacaga agtaacagca ttttctgtaa ttacagatta taagactgaa ataaaatatc
    25201 ctttagctga ttttaatata actccagatg tagctgtagt agattcagaa ttagctgaaa
    25261 caatgccacc taagttaact gcccatacag gaatggatgc attaactcat gcaattgaag
    25321 cttatgtagc aacattacat tcaccattta ctgatccact agctatgcaa gcgattgaaa
    25381 tgattaatga acatttattt aaatcatatg aaggcgataa agaagctaga gaacaaatgc
    25441 attatgctca atgtttagct ggaatggctt tctctaatgc actattagga atatgtcata
    25501 gtatggcgca taaaacaggg gctgtattcc atatccctca tggatgtgcg aatgcaatct
    25561 atttaccata tgtaattaag tttaattcaa aaacttcatt agaaagatat gctaaaatag
    25621 caaaacaaat ttcattagca ggaaatacaa atgaggaatt agttgattca ttaataaact
    25681 tagttaaaga attaaataag aagatgcaaa taccaacaac attaaaagaa tatggtattc
    25741 atgaacaaga atttaagaat aaggttgatt tgatttcaga aagagctatt ggagatgctt
    25801 gtactggatc aaatccaaga caattaaata aagatgaaat gaaaaagatt tttgaatgcg
    25861 tatattatgg tacagaagtt gatttttaat aaagtgcatt cttcaaaata aaactattat
    25921 ataggttcag tatattattg ctgaaccttt tttgttatgt accaattaat tctgcagttt
    25981 aataaaaata ttttctatta accaaaaaat aaatataaga gattcttgaa taggaaaaat
    26041 atagtgatat aatatattag gaaagaatta ttttccgtaa ggatataatg aaagccaaat
    26101 atatataatt atattttgga aaatagggga taatacataa gtatttgata ttatgaatta
    26161 tttgatgaat atacattgta aaatgaaaag gagttgcagt atggattata aatctataag
    26221 agagtgtaat gagtacatat taatagaaag tattaaaaat tttaagttaa agcagatctt
    26281 tgaatgtggt caatgtttta gatttgaaaa aataagcgat acaaattata ttgttgttgc
    26341 atttgaaaga gtgatagaac ttattgaaga tggtgaaaac atacttatat ataattccaa
    26401 tgaaagtgac gtacgggata tatggataaa gtattttgat ttgcacagag attattctta
    26461 tataaaaaat gaactttcta aagatgattt gcttagaaaa agcatagaat ttggaactgg
    26521 gatcagaata ttaaatcaag atccatttga gatattaatt agctttataa tttcagctag
    26581 aaatagtatt ccatcaataa tgaaaactat aaataaaatt tcaacaaaat ggggaactga
    26641 aattttatat aagggtaaaa catattatgc atttcctaca atagaacaga taaagaatgc
    26701 aacattagaa gagatacaag aaacaggtgc ttcttttaga agtaaatata ttatagatac
    26761 aattgctaat gtatatagta gcaaacaagc gatgaatcaa gaaagtttac aaaaaagaga
    26821 agaacttaaa aaatatgatt tagattatat aaaaagcttg aatgacgatg attgccataa
    26881 agcacttcag gaatttaagg gagtaggagc caaagttgct gactgtgtta tgttgttttc
    26941 tatggaaaaa tattcagcat ttcctgtaga tgtatgggtt aaacgtgcta tgattcattt
    27001 ttatggagca caggatgcat cactaaacaa gattaggatt tttgctagaa ataagtttgg
    27061 aaagttatct ggttttgcac aacaatatct tttctactat gcaagagaaa ataaaatcaa
    27121 aattgatgaa gagtagtaaa gaaaaactag tctattaaat atgctttaat gaactagttt
    27181 ttctttatta tattataata tattatattt tagctacttt ttctcacatg ttttgatttt
    27241 tttatagata tataagaatc acctggtata tcttttataa acttaagaaa ctttataata
    27301 cgaatatcat tctttaaact atttaatgaa ttgtaacgtg atgcaagttc acgatttgta
    27361 aataaagcat gtatttgtgt atgacaggta gtacaaagat atgctatctt aaagtgtttt
    27421 ccgccttttt ctaagggaat taagtgatgt tcagttataa tagaaacatt tctattacac
    27481 aattcacaga tatggttttg tgccataaaa tcctcctctt aatttcacaa gcttttataa
    27541 tttaattata acaaattaat tataaaaagc aaaataattc agaagattta aattatagga
    27601 aaattgttat atttttaaca ataatatggt ataattggat tataatagga aagcgcttat
    27661 taggagggtg tgtgtatgtt caaatttgaa aatcaacttt taaaacttaa acatgaagtt
    27721 cttacacggg ttgcagtact tgcaaaagaa aataaagtga ctaaggaaga aatagaaaaa
    27781 attccttata atatgatatc tggggaatcg cctacatata gagatactgt aactcaggaa
    27841 agagatgtag tattggaaag agcaaaactt gcagctgggt atcttccaaa tggaaaagaa
    27901 ggaaaagatt taatagatat atcagaacaa caacaaatat tatatgttat aaaagcagca
    27961 tgtgataggt gcccaacaaa aaaatttgaa gttacagatg cttgtagaaa ctgtattgca
    28021 cataaatgtc aaagtacatg taattttgga gcaattagtt atgttaatgg acgagcattt
    28081 attgatccaa gtaagtgcag agaatgcggt atgtgtaaaa aagcatgtcc ttacgatgca
    28141 attgctgaag atatgagacc ttgtaagcgt tcatgcccaa caggagcgtt aaattttaat
    28201 tctaaagact taagtgctga aattacagaa gataaatgtg ttaattgcgg agcttgtatg
    28261 gcagcatgtc catttggagc tatagaagat aaaagttcat tagttaaagt tataaataat
    28321 ctagttagta aggaaaaaat ttatgctgta gttgcaccag caataactgg agaatttgga
    28381 ccaaaaacaa cttatggaca agttaaaaat gcaattaagt cattagggtt tacagatatg
    28441 gtagaggctg cttgtggagc tgatgctgtt actgtgcatg aaagtaatga atttatagaa
    28501 agaatggaaa atggagatcc atacatgact aattcatgct gcccaggatt tttaagctat
    28561 attcaaaaga taatgccaga tcaagctgag agaatttcag gaactgtttc acctatggtt
    28621 gctgctggaa gatatataaa gtctaaagat aatggtgcaa aggtagtgtt tatagggcca
    28681 tgcactgcta agaaaagtga gattctaata gattcaatta aagattcaat tgactatgta
    28741 ctaacatttg aagagctatt agctttgttt gaagcgtttg aagttaatcc tgcaacttgt
    28801 gaagatataa tggtagatga tgcttcgata tttggtagag gatttggtat gggtggtgga
    28861 ttaactgctg ctatagagaa ttatatacaa gataaaggtg ctgaaataga attcaaacca
    28921 gttaaggttt caggtggagc agaaattaag aaaactatga caatggctaa agctaaaaaa
    28981 ttacaaggaa attttattga gggtatgatg tgtgaaggcg gttgtataaa tggaacggct
    29041 aaaattgcac cgctaatgaa agctaaaatg ccgtttacaa aaaataatgc acaatcatca
    29101 atgaaatctg tattatctaa taaagcgcta gaagagtata aaaacataaa tttagaaaga
    29161 taattatata tattgaataa ttaaaaaaga gtttattcaa tatatattat aaaattaatg
    29221 gataaataca ttgtttttat attgctaact aatttaatag attaattata ataaggaaga
    29281 gattttgcaa atatattaaa aaagtgtttt tgaaaggcta tattttatat ttggcaaaat
    29341 tctctttttt gttatttaaa gattaataga aaattaaaga aaaaatgagt aaaatgaatg
    29401 tatttttcaa taaagtctaa tatttgctta aaaagaggat ataatattag aagtaatgtt
    29461 tgaattatat gggtataaag gatattataa ttgtatcagc actcgacagt aatgagtgct
    29521 aacaggaagc taaaaaataa taaattataa tatatacatt ttaaggaggg tttttcatga
    29581 atattaaacc acttggtgac agagttgtaa ttaaaaaatt agaggcagag gaaaagacta
    29641 aaagtggaat agtcttaaca ggtactgcta aggaaagacc acaagaagca gaggttgtag
    29701 ctgtaggccc aggagctgtt gtagatggag ctagagtaca aatggaagtt aaaattggag
    29761 ataaagtttt atactctaaa tatgcaggaa cagaagttaa ggtagatgga gaagagtata
    29821 caatattaaa acaagaagat atattagcag tagttgaata ggaatttagt gagaataaaa
    29881 ttaagttatt aaaggagagt gtattataaa tggctaagat gttaaaattc ggagaagacg
    29941 caagaagaaa tatgcaaatt ggcgtagata aattagcaga tacagttaag gttactttag
    30001 gacctaaagg tagaaatgtt gtattagata agaaatttgg ggcaccatta atcacaaatg
    30061 atggagtgtc tattgcaaga gaaatagaat tagaagatcc atatgaaaac atgggagctc
    30121 aattagttaa agaagttgca acaaaaacta atgatgtagc tggagacggt actacaacag
    30181 ctactttact tgctcaagca attataagag aagggttaaa aaatgtaact gctggagcta
    30241 atccaatatt aattagaact ggtattagga tggctgtaga taaggcagtt gaagaaatta
    30301 agaagatttc taaaaacata gaaggaaaag aagatatagc tagagttgct gcaatctcag
    30361 ctgcagatga agaagtaggt aagttgatag cagacgctat ggaaaaagta ggtaatgaag
    30421 gcgttataac tatagaagaa tctaaatcaa tgggaactga attagatgtt gttgaaggta
    30481 tgcaatttga cagaggatat gtatcacctt acatggctac tgatacagaa aaaatggaag
    30541 ctattttaga aaatccatac attttaatta ctgataaaaa gattacaaat attcaagaaa
    30601 tattaccagt acttgaacaa atagttcaag caggtaagaa gctattaata attgctgaag
    30661 acattgaagg agaagcaatg gctacattag tagttaataa attaagagga acatttactt
    30721 gtgttgctgt aaaggctcca ggttttggcg atagaagaaa agaaatgtta caagatatag
    30781 ctatattaac tggtggtact gttatagcag aagaactagg aagagattta aaagaagtta
    30841 ctatagatat gttgggtaca gctgatagcg ttaaagtaac taaagaaaat acagttatag
    30901 ttaatggtaa gggtgaatca gcacaaatta aagaaagagt taaccaaatt aaagctcaag
    30961 ttgaagaaac aacttcagaa tttgataaag aaaaattaca agaaagatta gcaaaacttg
    31021 ctggtggagt tgcagtaatc aaagttggtg cagcaactga aactgaatta aaagaaaaga
    31081 aacttagaat tgaagatgct cttaatgcaa caaaagcagc tgttgaagaa ggtatagttg
    31141 ctggtggtgg aactgcatat gttaatgtta ttaatgaagt tgcaaaatta acttcagatg
    31201 ttccagatac tcaaattggt attaatataa tcgttaaagc attagaagaa ccggttagac
    31261 aaattgcaac taatgcagga gttgaaggat cagtaataat agaaaaagtt aagaatagtg
    31321 aagcaggagt tggatatgat gctttacatg gtgaatatat taacatgata aagggtggaa
    31381 tagttgatcc aactaaggtt acaagatcag cacttcaaaa tgctgcatca gtatcatcaa
    31441 cattcttaac aactgaagca gcagttgttg atattcctgc aaaggaatct ggaatgccag
    31501 caggggctcc aggaatgggc atggatggaa tgtactaaaa tagagcattt agcaagtaat
    31561 attagcagat aatattaaat agataagcta gaagacaaac acgtattgtt agtgtttatc
    31621 ttctagcttt tttatgttca tttttactaa ttaagatatt ggatttatat tttattattt
    31681 attaaaaaaa taaatttgtt taagttgaat aaaaagtata aataaaggaa taattctaaa
    31741 taaaatattg aatttagagg tgatttgaat ttataaagtt aattatttgc taaaaatgaa
    31801 agttaaagat aataaaagag agccatataa aaatagaaaa aaaggtggat ttacattaat
    31861 tgaagtaata gcagtaatag ctattatagg aattcttgca gctgcaattt tacctagagt
    31921 taacggttat ataaaagaag ctaaaaaagt gaaagtagta gatcagagta gaaaggttgt
    31981 aatggcagtt gaatcatata atttaaaagc tagtacacca ttaagcaaaa gtacaactgt
    32041 tcagactgct ataagcaatg aaggagtaaa aaagtatgta gatgagtctg aattaaaaaa
    32101 tttaaatact agagaaacta gtttgcaaaa ttgttatgac attctagatg gtgccgaatt
    32161 tgatatttct ggcgataatg atattttaga tccaaagaag attaagtaaa gtccaagtaa
    32221 aggattaaaa gttagaatgt aagataaaaa tgcaatttta atttcaaatt cattgacttt
    32281 gtattgtaca tacattataa tagttttaat tcaaaaacat agcacattta aaaactcgta
    32341 tataccttga atatggcaag gagtatctac cggagacctt aaatttccga ctatgggtga
    32401 tattaatata agctaaattt cgaattttat tagcatatta atatcactta gaaggttaat
    32461 gtgctttttt tgtacaaaaa aatataataa aatttgcagg aaaacaatca aaattaaaat
    32521 aaaacgaaat aaatgtttca aaactgggag gaattaaaat ggcaaaaata attaaacaag
    32581 catatacttt tgatgacgtg ttattagtac ctaataaatc aaatatatta ccaagagaag
    32641 taagtgtaaa aacacatttg actaaaaaaa tagcattaaa cataccttta atgagtgctg
    32701 gaatggatac agtaactgag tctaaaatgg ctattgcaat ggctagagaa ggcggaatcg
    32761 gaattataca taaaaatatg actgttgaac aacaagctaa agaagttgat agagttaaaa
    32821 gacaagaaaa tggagttatt acagatccta tattcttatc acaagatcac cttattcaag
    32881 atgctgaaaa tttaatgtct caatatagaa tctcaggtgt tccaattact actaaagaag
    32941 gtaaattaat aggaataatt actaacagag atataatttt cgaaacaaat ttccaaagaa
    33001 aaatttcaga agtaatgaca aaagaaaact taattactgc gccggagaat actacagttg
    33061 aagaagctaa agaaatatta aagaaacata aagttgaaaa attacctcta gttgataaag
    33121 aagggtattt aaaaggctta atcacaatga aagatattga aaaagtgaaa aagttcccaa
    33181 atgcagcgaa ggatggcaga ggtagattat tatgtggagc tggagttgga gttactggaa
    33241 atatgatgga aagaattgat gcgttagtta aagctcaagt tgacgttatt gttcttgata
    33301 cagctcatgg tcattcgcaa ggtgttttag aagctgttaa gaagattaaa gaagtatatc
    33361 cagaccttca agttatagct ggtaatgttg ctacagcaga agccgtagaa gacttaataa
    33421 aagcaggagc agattgtgta aaagttggta taggaccagg atcaatctgt actacaagag
    33481 tagtagccgg agttggagtt ccacaattaa cagctgttat ggattgtgca gaaatgggta
    33541 gaaaatatgg aatacctgta attgcagatg gtggacttaa atattcagga gatgtagtaa
    33601 aagcattagc tgctggagca tcagttgcaa tgatgggatc attatttgca ggttgtgaag
    33661 aagcaccagg agaaatggaa atatatcaag gaagaagtta caaagtatat agaggaatgg
    33721 gatctttagc agctatggaa tgtggatcta aggatagata cttccaagaa ggtaataaaa
    33781 aactagttcc agaaggtgtt gaaggaagaa tagcatttaa aggatctgtt acagatacta
    33841 tattccaatt aataggtgga ataaaatctg gaatgggata tttaggatca aaggattttg
    33901 atactttata tgaaactgct acattcgtga ttcaaacagc agcaggattt agagaaagtc
    33961 atccacatga tattaatatt actaaggaag ctcctaacta tagtgtagga caataataaa
    34021 agttatgatg cacagttcac aatttattga ggtagcattg ctggactgtg cattacttag
    34081 tttgattaga aagaaatatc gaaaattcta tgtaaataaa gaaattaagt caaaaataat
    34141 ttaatttctt gataaaaagt tctatttagt taataataga cattagaaaa agaattttag
    34201 gaggaaagca tgaagagaga gttaatttta gttgtcgatt ttggtgggca atataatcaa
    34261 ttaatagcaa gaagagtacg agaatgtaat gtatattgtg aagttcatcc ttataattta
    34321 agtgttgata agataaaaga aatgaatcca aagggaa
//
