LOCUS       c00003_NZ_CZPX..       23467 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CZPX01000004.1 Actinomyces ihuae strain SD1, whole genome shotgun
            sequence.
ACCESSION   NZ_CZPX01000004
VERSION     NZ_CZPX01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:06:05
            Original ID  :: NZ_CZPX01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 669220
            Orig. end    :: 692687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23467
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[679220:682687]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13467
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..23467
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23467
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="3"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             709..1581
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 70; E-value: 7.2e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_588"
                     /sec_met_domain="BPD_transp_1 (E-value: 8.1e-21, bitscore:
                     70.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGSNRLGRTVTGYALLVPSLIGVLVFLLAPIGIVIWLSFQRWDLI
                     APRQFVGFDNWVSVLTGPDLVNSLIVTALLVLLVIPIQTLLGLLMAALMVKGLPGSGVF
                     RVIYVIPWVCAPLALGIVWKWIFAPTGGALNALIGARVEWLTDPTLALPAVAFVSIWSQ
                     VGYVALFFMAGLAAIPEDIIEAARVDGASDTRIFWSIKVPLIRPTMFFVLVTSTISVFQ
                     MFDQIFALTEGGPAKRTEVLSYRIYNLAFTNFDLGRASVTALVLFVILVAITLIQNRYF
                     SRRMTYEYS"
     CDS             1568..2422
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 75.4; E-value: 1.5e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_589"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.8e-22, bitscore:
                     75.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRKRGVAAVWTNTLVYAILVIGAVLVLAPFALSVMTSLKTPR
                     QFATSSPLEPPAPPTLDNFTNLFAGGTKVDFSRAFGVTFAVVIVVLVGQLLFSIMAAYA
                     FARISFPGRDAVFWVYLATLMVPQVVTIVPLYLMMAQSGLRNTFWALVLPYVFGSPYAI
                     FLLREYFRSIPQDLIDAARLDGAGTIRVLTRIVVPMSRPIIATLALITVVTHWNNFMWP
                     LIVTTGQDWAVITVATSSLQSQYTNNWTLVMAATTIAMAPLILIFALFNRRIVDSIAIT
                     SFK"
     CDS             2452..3816
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 139.2; E-value: 9.8e-43)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_590"
                     /sec_met_domain="SBP_bac_1 (E-value: 1.1e-41, bitscore:
                     139.2, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLRKPLLAGILGMALALAACSSGGSGQSGESGGTASNSGAATT
                     VTLRLWDEGAAGAYEESLAAFHEQNPDIAVEISVVPWSDYFTKLRTDIAAGSMDDLFWI
                     NNSSYTSYAKSGNMVNIDEALGAEARDQWDANVVKAFTLDDTLWGVPQLSDAGIALYYN
                     KTLLDEAGVTPDDLANAKWSPQGGDDTLINLLKKLTKDDSGNTADSTDFNADSISQYGY
                     NAAQDLQAIMLPFIGSNGGTFQNGDQFTFSDARTTQAMQYVVDLITKEHVAPSAADTNM
                     DGEFTRNQFLQGNMAIFQSGLYNLATIAESADFEWGTALLPEGPAGRVSVTNGIVVAGN
                     AKSENPEAVAEVLEWLGSQEGNEYIGKNGTNLPAVTAAQQVYFDFWKDKGIDIQPFFDV
                     VADGAPTIDPPVGDNFTAASAAYTEVLNEVFQGRVPVAEGMKTADEKANAAMNGE"
     CDS             complement(3856..4926)
                     /locus_tag="ctg3_591"
                     /transl_table=11
                     /translation="MMNFLPTGTPWLPSTDRYSTMPTARCADSGLQLPRIALGLWHNFG
                     DDRPFQTQRDIIRFAFDHGIYHFDIANNYGPPAGSTEENFGRIFAKDLRAHRHELVIST
                     KAGWEMWEGPYGQGGSRNYLLSSLDESLTRMGLDYVDIFYHHRPEGETRLEESMMALRD
                     AVASGKARYVGISSYSAHATIQAQSIMRELGVPLVIHQPSYSMLNRWVEEGEPSLLDTA
                     AEQKMGVIAFSPLAQGMLTDKYLDGIPENSRLGVGKVSREFFTDETLDHIRALNDIAHE
                     RGQDLAQMAIAWVLRDQGARTVTTALVGASSVEQLSNSLGALDATDFSDEELQAIDVHA
                     VDSGINQWWGATETRP"
     CDS             5037..6812
                     /locus_tag="ctg3_592"
                     /transl_table=11
                     /translation="MSSFFVRTLREDPADAEVTSHKLLVRAGYIRRAAPGIYTWLPLGL
                     RVVRKVEQVVREEMDRIGAQEVLFPALLPADPYKQSHRWEEYGPTLFKLRDRKEGDYLL
                     APTHEEMFTLLVKDMYSSYKDLPVTLYQIQTKYRDEARPRAGLIRGREFIMKDAYSFDL
                     DDDGLDASYDLERSAYEAIFKRLDLEYVICSAMSGAMGGSRSEEFLHPCTIGEDTFVRS
                     AGGYAANAEAVKTPAPDPLPIEGQRQAVVYPTPDSTTIDALVTFANDEHPREDRPWEAS
                     DTLKNVVVALTHPDDTREVVVIGVPGDREVDMKRLEAAVSPARVEIATGEDLAQHPELV
                     AGYIGPDVLGPNARGIEHPVRYLLDPRIVDGTSWITGANEVERHVFGLVKGRDFTADGW
                     IEAAEVREGDPAPDGSGPLHLERGIEIGHIFQLGRKYAEALGLTVLDENGKSRIVTMGS
                     YGIGVSRVMAALAESTSDEKGLSWPAHIAPFDVHVLATGKGEEIFTTARDLATQLDAAG
                     LDVLYDDRPKMSAGVKFADSELIGIPITLVVGRGLTDGVVEIRTRATGERHEVPVDEAL
                     MRVSELHQDLMNQGQ"
     CDS             6812..7303
                     /locus_tag="ctg3_593"
                     /transl_table=11
                     /translation="MAIRDIRIIGDPILRTPCEEITTIDDHVKMLVEDLLEGVDMDGRA
                     GLAANQIGVGLRAFSWNIDGEVGYILNPRIVELSKDEYQDGDEGCLSVPDLFFPTERAW
                     YARAEGIDLDGKPVVVEGEELMGRCIQHECDHLDGKIYIDRLDRKNRKEAMRAIRKMGL
                     "
     CDS             7307..8170
                     /locus_tag="ctg3_594"
                     /transl_table=11
                     /translation="MREHGDALCLNHAFWQEQASRHAQSPFYDVNTLVNDRAKIPEAIR
                     LDRPYLEGAGIEGGDVIHLQCHIGTDTVGLARLGAHRLVGLDFSEESLEIARGIADRAG
                     LHIDYVCSDVLSAHEAVEERFDIVYTSEGALAWVPDIRRWAHVVASLLKPGGTLVVRDV
                     HPLVGTLKDPVQCDALELHFPYFETREGITWDDDSSEADYAGSSVTPGKNATVEWNHSL
                     GQIVNALSDEGVFVKRLDEIDELFFPMSPDMKRCGPSSWKLPESAPTCALPLSFRIVAT
                     ADLTSC"
     CDS             complement(8157..8912)
                     /locus_tag="ctg3_595"
                     /transl_table=11
                     /translation="MDDFFRGVESPGMIDWPSMPTYNTLMAVAAGAALIGLAMFFREVR
                     SNSGKTAVRVDGYAMAFGALGLILTTTGLHMTTTWPLAAGGFAYDNVIFGETCLGFGSL
                     LLFACFYLWKQRDHIARSQKALSELLHAAKPLSIFAGGLGLGLWGIAFAGVMYRLFTAP
                     PQEPISGWFAQWPWFEAIFMSLFFFVIGLGCVLFPIGVFRADKEGTSESRGGGILNAVM
                     WLWLACGVAIGLFGCLNFYTHIGLIVNTM"
     CDS             9126..9626
                     /locus_tag="ctg3_596"
                     /transl_table=11
                     /translation="MSRSYTRGVLFVHSTPPALCPHIEWAVGTALGQEVHLQWTDQDAA
                     PGMVRSEFSWVGQTGSGARLASALRGWEHLRYEVTEEATAITDGGRWSHTPSLGIFHAQ
                     MDTAGNVVVPEGRIRAALDESHSPTEMIDKLNLALGQAWDDELEPFRYAGAGAPVRWLN
                     RVG"
     CDS             9630..9947
                     /locus_tag="ctg3_597"
                     /transl_table=11
                     /translation="MGSIGDQLGIDLTELLDMDEPPQSDQEDNDTVGEAVMNALLEETS
                     IEPDRMRADLTLEGDLDLDTLGRYSVISQIEHELGITLIDRDVDALTTVEDLLNLARST
                     S"
     CDS             10001..12715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 213.8; E-value:
                     1.6e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_598"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.8e-64, bitscore:
                     213.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-32,
                     bitscore: 108.0, seeds: 739, tool: rule-based-clusters)"
                     /sec_met_domain="SucD_FumR (E-value: 9.7e-06, bitscore:
                     20.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINGTLTPTARRVTIPTWVCKVVMAITGLIMAAFVFIHMVGNVK
                     ILTDPAQMDHYAQWLRTIGEPALPYGSVLWILRVILLSCVLLHICGALILWRRGALTHT
                     PGVRRLKHRGWAAKLMLPTGLVLIAFIVIHILDLTIGTVVESAAFRHPDSRFYAAANVV
                     ASMSRPVMFAAYVIALIAIGLHLSHGIERAWQDLGGRSPRIGTVVRIAGYAIALAVVIG
                     DLTVIAASHMGAISVALALPLAAGRTHLRIDEGAPVDAHEPEVEPERMWDEFVSHARLV
                     SPGNRRTFRVVVVGTGLAGASAAAALAELGFGVDAITTLDTPRRSHSVAAQGGINAARA
                     RRVDSDSVQRFVTDTIKGGDFRARESEVWRLGIESARVIDHMNALGVPFAREYGGSLST
                     RSFGGVQVSRTYYSRGQTGQQLQVAASSSLMRQVAAGRVTLWVRHEMLDVVVADGRAAG
                     VITRDMITGRTRFHPAHAVVIATGGYGNVYYYSTLAKNCSTTGIWRAHRAGAALASPSM
                     IQFHPTALPVSFPWQSKTTLMSESLRNDGRIWVPRSPGDDRDPNTIPEEERDYYLERKY
                     PAFGNLTPRDIASRAAREQIESGHGVGPERNSVYLDFRDALERVGRRVIAERYGNLLDM
                     YLDATGEDPYTRPMRIAPGAHFTMGGLWVDFRLMTTIPGLFAAGEANAAYHGANRLGAN
                     SLLAACVDGAFTIPRTVPDYLAGILGQELLSVDDSRVIAAREGVESRLQGLLHIDGATP
                     TDSFARKLGDIMYQGCGVVRSKESLEAALSDIDALQQRMGADLRVSGETGHFNTDLVAA
                     ARLQDSIQMATLMCVDAWHREESCGAHFRSEYQTEQGEAQRRDDQWMNVSAWTTDGWHD
                     LRTDGAAPLAITCTHHAEELTFTTVPLATRNYQ"
     CDS             12712..13467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_599"
                     /sec_met_domain="Fer4_7 (E-value: 3.2e-11, bitscore: 39.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.2e-07, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 3.3e-23, bitscore: 77.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 22.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIVDVWRQKAPEAVGTFHSYELDGCDERMSILELLDHLNRNLS
                     SRGVEPVAFDSDCREGICGACGIQVDGRPHGFSENLPACMQRVGAHADGTHVRLEPLRS
                     GAFPVIRDLVVDRSVLDRITMAGGFASVDTGLAPDADAIPIRHQDAEGALDLAACIGCG
                     ACVAACPNGSAALYAGARMGHLAALNIPGLERAERARRMNEAMDQYFGSCSGYGECIRV
                     CPANIPFDVVAVASHERLRALWSRWPQPR"
     CDS             13533..14987
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_600"
                     /sec_met_domain="Lyase_1 (E-value: 5.6e-99, bitscore:
                     326.8, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 1e-14, bitscore:
                     50.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGNRSEEDLLGSRDVPQEAYWGIHSLRAQENYQISGRTINEVPEL
                     IRAFAQVKKAAALANKDLRVLKPATADAIVQACDAIIDEGACLDQFPIDQFQGGAGTSV
                     NMNANEVIANLALEMTGQERGRYDLINPNDDVNHSQSTNDTYPTAFRLAAYEKVDQLRH
                     AVNDLADAFERLGARYQHVLTMGRTQLQDAVPMTIGQEMTAFGVTLREEDPRLVNVANL
                     LLETNLGATAIGTGLNTPPGYQKAVVAHLREITGLDVTASEDLIEATSDAGAYISMHAT
                     MKRTAGKLSKICNDLRLLSSGPRAGLNEINLPQRAAGSSIMPAKVNPVIPEVVNQVCFK
                     VIGNDVTVTMAAEAGQLQLNVMEPVIAQCMFESATLLTHACDTLREKCVDGITVNEENC
                     RNMVMNSIGIVTYFNDVIGHHAGDVVGKRAAAENKNVGDLIVEMGFLSQEQVDEILSPE
                     NLANPQYRGAKISDDPETPKQASSKH"
     CDS             complement(15079..17829)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_601"
                     /sec_met_domain="Transketolase_N (E-value: 6.8e-12,
                     bitscore: 40.4, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSTNQKHPVINGLLSQIPDNDPDETQEWIDSLTSLIDEKGGPRAR
                     YILLHMMDEARKRDVQLPQEYTTPYVNTIPVDQEPYFPGDEAMERQYRRWIRWNAAVQV
                     TRAQRPGVGVGGHISSYASVATLYEVGLNHFFRGKDHPGGGDHIFFQGHASPGPYARAF
                     LEGRLTEEEMDGFRQQVSVDGGLPSYPHPRQMPNFWEYPTVSLGLGPAEAIYQAWFDRY
                     LQLRGIKDTSQQHTWAFLGDGEMDEPEARGMLQLAAQQGLDNLTFVVNANLQRLDGPVR
                     GNGKIIQELEAFFKGAGWNVIKVIWGRGWDQLLAADKDNALVHLMDETLDGDYQTFKAK
                     DGAYVREHFFGRDPRTKALVKDWTDEQIWALGRGGHDYRKVYAAYKAAMEHTGQPTVIL
                     AHTIKGYALGTHFAGRNSTHQMKKLTLEDAKALRDRLQIPISDEELEKDPYKPPYYMPP
                     ADDPALLYMKERREKLGGYLPERRAHDDAHLPEPAMKPFEALSKGSGKLEVATTMALVR
                     LLKDLLRDKNIGRHIVPIIPDEARTFGLDAIFPSARIFNTHGQNYTAVDADMMLSYKES
                     EQGQVMHTGITEAGSAAALQVVGTSYATHNLPMIPFYIFYSMFGFQRTGDQFWAAADQL
                     TRGFVVGATAGRTTLTGEGLQHLDGHSPILGAANHGFVLYDPAYAYEIRYIMWDGIKRM
                     FCEHDPSDTRDPNVMYYLTVYNEPIHQPAKPENVDVDGIIKGIYKVDDHTGQGPKAQLL
                     ASGVAVPWAREARKLLAEDWGVDAAVWSVTSWNELRRDGVEADEHNFLHPNEDPRYAYL
                     TTKLSGSEGPFIGTSDYDALIIDQIRPWVPGYLYTLGADGFGISDTRRAARRYFHIDAE
                     SMVVRTLQALADQNQVDRAVVEQAIEKYQLHNVRIGADEAAASDE"
     CDS             18131..18532
                     /locus_tag="ctg3_602"
                     /transl_table=11
                     /translation="VAISLGFTQNQVVQEFYVDDDSDEAVRDAVARETGHELVDVDYGD
                     VVDGALVWWRADDAEEEDLGDVLVDVASNLDDGGMIWVLFPKPSDPNTVPVADIAEAAS
                     VAGLHSTSAFSMGDTWTGICVTARPRAHR"
     CDS             complement(18691..19539)
                     /locus_tag="ctg3_603"
                     /transl_table=11
                     /translation="VNDTPMMTLPDGPIDIRLIASDMDGTLLDGNSNLPDEFWPLMHEL
                     AVRDIAFVPASGRQLATLDTMFSGTDAGHSYIAENGSIVTFHGQVVSTTCIDMPTVNEM
                     IDVTRRVSSDGSYNLGLVVCGQNSAYVERTDAEFYAEAHKYYAQLEVVDDLKQAAAHDN
                     VLKLATYDFTDISAFVDDQVPHLRQSHQVAESSRHWVDMMNPVANKGRGLTALQESLGI
                     GPEHTVVFGDFLNDLELFDHADYSYAMANAHPDVTARARYRAPSNIDHGVMTVVRALLA
                     L"
     CDS             complement(19612..19845)
                     /locus_tag="ctg3_604"
                     /transl_table=11
                     /translation="MSRRENSNQLPVAPLLATKKLPLGAQVIWTFAFAAFWALMAYLTW
                     RWFVVLTVVFGMYGIYLSICYVQRRHATRMKE"
     CDS             complement(19930..21390)
                     /locus_tag="ctg3_605"
                     /transl_table=11
                     /translation="VSEEQDIDTGEARARSMRSSLDNYELSESDLQILDDHEGDLPSST
                     EMDGLPVLAVIGRPNVGKSTLVNRILGRREAVVQDTPGVTRDRVTYQAEWAGREFLVVD
                     TGGWEVDVRGLDRNVADQAEVAIDLSDAVLLVVDATVGITTTDERIVELLRRSGKPVIL
                     AANKVDSAMQEADAAYLWGLGMGEPYAISALHGRGTGDLLDRVLAVLPERSARAGQPRD
                     PNIRRVALVGRPNVGKSSLLNALVGHERVVVDSTAGTTRDPVDEIVTLGDRQWQFVDTA
                     GVRRKMHRTTGADFYASIRTQAAIEKAEVALVLFDASEVLTEQDVRVVQQVVDAGRALV
                     IVNNKWDLVDEERQKELKSELERELVQVAWAPRINISAATTWHTNRIVQALDTALAGWE
                     TRISTGKLNAFLGQLVAAHPHPLRGGKQPRILFGTQVSSAPPRFVLFTTGFLDPGYRRF
                     IERRLREDFGFAGSPVQISVRVRERRRK"
     CDS             complement(21396..22967)
                     /locus_tag="ctg3_606"
                     /transl_table=11
                     /translation="VCAMTTINELRPRTSAITFRELVRDLDVHQWVNEDKANCPVTGVT
                     VSSSDIDAGWVFVAIPGYSHHGAEFAAGALEAGAAGVITDEKGARILRDSGASVPIAVV
                     DDPRQAAAFVSARVVGNPDQSLTTAAVTGTNGKTTTTYLVSAALGAIHDVPALCGTVET
                     RIGDMTILATRTTNEAPVLHRFLACAQQQGADNAVIEVSSHALSLNRVDGIVFDVAIFT
                     NLQHDHLDFYHDMEHYFQAKASLFTPEHALRGIVCVDDEWGQRLAREATIPITTVAALS
                     SQQADWHVSDIHPDPQTAQTVFSLTDPAGHTHQVHSPVLGEVNVQNCAVAIAAATAVGA
                     DSDQAVTALERAPQVPGRMEKINPDCDDQPLVIVDYAHTPEALEWILKDARELAGGRVV
                     LVFGTDGDRDASKRIPLAEVAARHADVLWVTDENPRTEDAAAIRAELMEGIRNVRPDLT
                     NVTEVTTCRRDAVRCAIQDASANDIVLITGKGAEWYQEIDHVYHRYNDVPVAREVLEYS
                     EPRKRG"
ORIGIN
        1 gtttgagcaa tacgacttcc acgacttcaa gatttctgtc aagcaccacg atcctgtcac
       61 gatgatccgt gcctatgagc tcttgtccga acgaggggac tggccgctcc acttgggtgt
      121 cacggaagct ggaccggcct tccagggcac catcaagtcg gctaccgcct ttggcgccct
      181 gttgcgtgag ggcatcggtg acacgatccg cgtgtccttg tcggcaccgc ccgtcgagga
      241 agtcaaggtt ggcattcaaa ttctgcagtc aatggggctg cgcgagcgca cactggaaat
      301 cgtgtcatgc ccgtcatgcg gccgcgcgca ggtcgatgtg tattccctgg ctaacagtgt
      361 gactgagggg ctgaaggatt tgacggttcc cctgcgcgtc gccgtcatgg gatgcgtcgt
      421 gaacggacca ggtgaagcac gcgaagccga cctgggtgtg gcatccggca acgggaaagg
      481 caagatcttc atcaagggtg aagtggtcga aacagtgccg gaagatcaga ttgttgaaac
      541 actgattcgc cgcgcaaacc tgctcgccga agaaatgggc cttgaagaag gcgacggtca
      601 cgtcgaggtc atccctgccg gagcacggtg atcaccgtga ggtgcgcgtc gagcggggat
      661 attgtgtacc gttgaaagat agcctggaag tgcggaaggg agcggctcgt gggtagtaat
      721 cgcctgggtc gaaccgtgac aggttatgcg ctcttggtgc ccagtttgat cggtgtgctc
      781 gttttccttc tggcacccat cggcattgtg atctggctga gctttcagcg ctgggatttg
      841 atcgcaccgc gccaattcgt cggattcgac aactgggtat ctgtccttac cggacctgac
      901 ctggtgaact ccctgatcgt cactgcactc ctggtgctgt tggtaattcc cattcagaca
      961 ctcctcggcc tgctgatggc tgctctcatg gtgaaaggac taccaggctc gggagtgttc
     1021 cgcgttatct acgtcatccc gtgggtgtgt gcgccactgg ctctgggcat cgtgtggaag
     1081 tggatttttg cccccaccgg cggtgccctg aacgcactga tcggcgcccg ggtcgaatgg
     1141 ctgaccgatc cgacattagc cctgccagca gtcgcattcg tatccatctg gtcccaggtc
     1201 ggctacgtcg ccctgttttt tatggccggt ctggcagcga taccagaaga catcattgag
     1261 gcagcgcgcg tcgatggagc atccgacacg cgcatcttct ggtcaatcaa ggtgcccctc
     1321 atccgcccga cgatgttctt cgtactggtt acgtccacca tttccgtctt ccaaatgttc
     1381 gaccagattt tcgcgctgac cgagggcggc ccggccaagc ggacagaggt actgtcctac
     1441 cggatctaca acctggcgtt cacgaacttt gatctgggca gagcgtcggt gacggcgttg
     1501 gttctcttcg tcatcctggt ggcaatcacg ctgattcaga atcgctactt ttcccggagg
     1561 atgacctatg agtactccta ggaagcgtgg cgttgccgcg gtgtggacga acacccttgt
     1621 ctacgcaatc ttggtcatcg gtgcggttct ggttctggca ccgttcgcgt tgtctgtcat
     1681 gacgtcgttg aagacaccaa ggcagttcgc tacctcgtcg cctcttgaac ctcccgcacc
     1741 gccgactctg gacaacttca cgaacctgtt tgcaggtgga acgaaggtcg acttcagccg
     1801 cgccttcggc gtaacgttcg ccgtcgtgat agttgtcctt gtgggccaac ttcttttttc
     1861 catcatggcc gcctatgctt tcgcgcgtat cagttttcct ggtcgtgacg ccgtcttctg
     1921 ggtgtatctg gctacgctca tggtgccgca ggtcgtcacg atcgttccgc tgtatctgat
     1981 gatggcgcaa agtgggctgc gcaatacgtt ctgggcattg gtgctgccgt atgtcttcgg
     2041 ctccccgtat gcgatcttcc tgcttcgtga gtatttccgc tccattcctc aggacctgat
     2101 cgacgcagcg cgcctcgatg gtgctggaac tatccgagta ttgactcgga ttgtcgtgcc
     2161 tatgtcccgc ccgattatcg caactcttgc gttgatcacg gtagtgacgc actggaacaa
     2221 cttcatgtgg ccgttgattg tgacaaccgg ccaggactgg gcagtgatca ccgtggcgac
     2281 ctcgagcctg cagtcccaat acaccaataa ctggacgctg gtcatggctg ccaccacgat
     2341 tgcaatggca ccgttgatcc tcatatttgc gctcttcaat cgtcgtattg tcgattccat
     2401 tgcgatcacg agctttaagt agaccccacc acaacacgaa aggatgaagc gatgacacat
     2461 ctgcgaaagc cgcttcttgc aggaattctg ggcatggcat tggctctggc tgcctgcagc
     2521 tcaggaggat ccggtcaaag cggcgaaagc ggggggaccg cttcgaattc aggagctgcc
     2581 accactgtga ccttgaggct gtgggacgag ggggccgccg gcgcctacga agaatcactc
     2641 gctgcatttc acgaacagaa tcctgacata gctgtggaga tttccgtcgt cccgtggagc
     2701 gactacttca ccaagttgcg cacggatatc gctgccggct cgatggatga cctgttctgg
     2761 attaacaact cgtcctacac gtcctacgcc aagagcggca acatggtcaa tatcgacgag
     2821 gcattgggcg ccgaagcgcg cgaccagtgg gatgccaatg ttgtcaaggc cttcaccctc
     2881 gatgacacat tgtggggcgt gccgcagctg tcggacgctg gaattgcgct gtactacaac
     2941 aagactctcc tcgatgaagc tggcgtgaca ccggacgacc tcgccaatgc gaaatggtca
     3001 ccgcagggcg gcgacgacac gctgatcaac ctgctcaaga agctcacgaa ggatgacagc
     3061 ggcaatactg ctgattcaac cgacttcaac gcagattcga tcagccagta cggctacaac
     3121 gcggctcagg atctccaggc aatcatgctg ccctttattg gctccaacgg cggcacgttc
     3181 cagaacggtg accaattcac cttctctgac gccaggacca cacaggccat gcagtacgtt
     3241 gtcgacctga ttaccaagga acacgtggct ccctcggcag ccgatacgaa catggacgga
     3301 gaattcactc gtaaccagtt cctccagggc aacatggcga tcttccagtc cggcctgtac
     3361 aacttggcca ccattgcgga aagtgccgat tttgagtggg ggacagcgct tctgccggag
     3421 ggtcccgcag gccgtgtctc tgtcaccaac ggcatcgtcg ttgcgggcaa tgcgaagagt
     3481 gagaaccccg aggctgttgc cgaggttctg gagtggctcg gttcccagga aggcaacgaa
     3541 tatatcggaa agaacggcac gaatctgcct gcggtcacag cggcgcagca ggtctacttc
     3601 gatttttgga aggacaaggg gatcgacatt caaccgttct tcgacgttgt cgccgatggt
     3661 gcgcccacca ttgatccgcc tgtaggcgac aacttcacgg ccgcgtcagc cgcgtacacc
     3721 gaagtcctta acgaggtctt tcagggacgc gttcccgtcg ctgagggtat gaagacagcg
     3781 gacgagaagg cgaacgccgc catgaacggc gaataagacg tctaccgctt gcgcggccgt
     3841 gaggcagtcg gtgcctcacg gccgcgtttc agttgcgccc caccattggt tgatgcctga
     3901 atccaccgca tgcacgtcga tggcctgcag ttcctcgtcg ctgaagtcag tggcatcgag
     3961 tgctccgaga gaattcgaca attgctccac gctggaagct ccgaccaatg cggtggtcac
     4021 ggtgcgcgct ccctgatctc gcagcaccca cgcgatagcc atttgagcca gatcctgtcc
     4081 acgctcatga gctatatcgt tgagggcgcg aatgtgatcg agcgtctcat cggtgaagaa
     4141 ttcgcgcgaa actttaccca cgccgagccg tgaattctca ggaatgccgt ccaggtactt
     4201 gtcggtgagc attccctgcg ccagaggaga aaacgcgatg acgcccatct tctgttcagc
     4261 ggcagtatcc agcagcgagg gctcgccttc ttcaacccat ctgttcagca tcgagtacga
     4321 cggctgatga atcacgaggg gaacgccgag ttcacgcatg atcgactgcg cctgaatggt
     4381 tgcgtgcgcg ctgtaggacg aaatcccgac gtagcgtgct ttgcccgatg ccacagcatc
     4441 acgcagcgcc atcatcgatt cttccaggcg cgtttcgcct tcaggacgat ggtggtagaa
     4501 gatgtccacg taatcgagcc ccatacgggt caatgactca tccagagatg acaacaagta
     4561 gttgcgggag ccgccctggc catagggacc ttcccacatc tcccatcccg ctttcgttga
     4621 aatgacgagc tcgtggcgat gtgcccgcaa atccttcgcg aagatcctcc cgaagttctc
     4681 ttccgtgctc cccgctggag gaccgtagtt attggctatg tcgaagtggt aaataccgtg
     4741 atcgaatgcg aagcgaataa tgtcacgctg tgtctggaac gggcggtcgt caccgaagtt
     4801 gtgccacagt cccagtgcaa tgcgagggag ctgcaaacct gagtccgcgc aacgcgcggt
     4861 cggcatggtc gaataacggt ccgtcgaagg cagccaggga gtaccggttg gaagaaaatt
     4921 catcatggtt ctattgtctc gtgctgctgg tcgcctcgct tggattccga catctcaggg
     4981 acaggatctg acaggaagcg cagtggtgaa ctaatctgga agacgtgctg aaaactatgt
     5041 catctttctt tgtccgcacg ttgcgtgaag atcccgccga cgcggaagtc acctctcata
     5101 agctcctggt gcgcgctggt tacattcgtc gtgccgcacc cggtatctac acgtggctcc
     5161 cgttgggcct gcgagtggtg cgcaaggtgg agcaggttgt gcgtgaggaa atggacagga
     5221 tcggtgcgca ggaagtgctg ttcccagctc tgcttccagc cgacccgtac aagcagtccc
     5281 accgctggga ggaatacggc cctacgctct tcaaactgcg tgaccgcaaa gagggggact
     5341 atctgcttgc ccccactcac gaagagatgt ttaccctgct ggtcaaggat atgtactcct
     5401 cgtacaaaga tcttcccgtc acgctgtacc agattcagac caagtaccgt gacgaggctc
     5461 gtcctcgcgc cggtctgatc cgcggacgcg aatttatcat gaaagatgcc tactctttcg
     5521 accttgacga tgacgggctg gatgcctcct acgacctgga acgttcggca tacgaagcga
     5581 tcttcaaacg tctggacctt gaatacgtca tctgttcggc aatgtccggc gcaatgggcg
     5641 gatcacgctc tgaagagttc ctgcatccgt gcacgattgg cgaagataca tttgttcgct
     5701 ctgcaggtgg gtatgcggcc aacgcggaag ctgtcaagac accggcaccg gacccgctgc
     5761 caatcgaagg tcagcgccag gcagttgtct atccgacgcc ggattccacg acgatcgacg
     5821 cactcgtgac gttcgcgaac gacgagcatc cgcgtgagga tcgcccgtgg gaagcatccg
     5881 acacattgaa gaacgtggta gtggcgttga cgcatcctga cgacacgcgt gaagtcgtgg
     5941 tgatcggtgt gccaggtgac cgagaagtcg atatgaagcg cctagaggcc gctgtttcac
     6001 cggcgcgtgt tgagatcgcg accggcgagg atctggcgca gcatccggag ctggtcgccg
     6061 gttacatcgg ccccgacgtc ctaggcccca atgcacgggg cattgaacac cctgtgcgct
     6121 acctgctcga tccgcgcatc gtggatggca cgtcgtggat cacaggcgcc aatgaggtcg
     6181 aacggcacgt ctttggcctt gtcaaggggc gtgactttac tgcagatggc tggatcgaag
     6241 cggccgaggt acgcgagggc gaccccgcac ctgacggctc cggtccgttg cacctggaac
     6301 gcggcatcga aatcggccat attttccagt tgggacgcaa gtacgccgag gcgttgggcc
     6361 tgaccgttct ggatgagaac ggcaaatccc gcatcgtcac gatgggctcc tacggtatcg
     6421 gcgtgtctcg cgtgatggcg gccttggctg aatcgaccag cgatgagaag ggcttgtcat
     6481 ggcccgcaca catcgcaccc ttcgatgttc atgtcctcgc cacgggcaag ggcgaggaga
     6541 tcttcacgac ggcgcgcgat ttggccactc agttggatgc tgcaggtctc gatgtgctct
     6601 acgatgaccg tccgaagatg tcggcaggcg tcaagtttgc tgacagtgag ttgatcggca
     6661 ttccgatcac cctcgtcgtt gggcgtggcc tgactgacgg tgtcgtggaa atccgtacga
     6721 gagcgacagg tgagcgccat gaagttcccg tggacgaagc gctcatgcgt gtcagtgaac
     6781 ttcatcaaga cctaatgaat caggggcaat aatggcaatt cgtgacattc gcataatcgg
     6841 agatcccatc ctgcgtacgc cgtgcgagga gatcacgacg attgatgacc acgtgaagat
     6901 gctggtcgaa gatttgcttg agggcgttga tatggacggg cgtgcgggtc tcgcggccaa
     6961 ccagatcggc gttggtctgc gtgcgttctc gtggaacatc gatggggaag tgggctacat
     7021 cctgaacccc cggatcgtcg agttgtccaa ggacgaatat caggatggcg atgagggttg
     7081 tctgtcagtt cctgacttgt tcttcccaac tgagcgtgcc tggtatgccc gtgccgaggg
     7141 gattgacctg gatggcaagc cagttgtcgt cgaaggcgag gagctgatgg gtcggtgtat
     7201 tcaacacgaa tgcgaccacc tggacggcaa gatttacatt gatcgccttg accgcaagaa
     7261 ccgtaaggaa gcgatgcgcg cgatccgcaa gatgggtctg tagctgatgc gtgagcacgg
     7321 tgacgcactc tgcctcaatc acgccttctg gcaggagcag gcatcacgtc acgctcagtc
     7381 accgttttac gacgttaaca ctctggtgaa cgatcgcgcg aagattcctg aggctatacg
     7441 cttggatcga ccgtacctgg agggcgctgg catcgagggc ggcgacgtca tccaccttca
     7501 atgccatatc ggcaccgaca ctgtaggact ggcacgcttg ggggcgcacc gtctggttgg
     7561 ccttgatttt tccgaagaat ccctggagat tgcacgcggc attgccgacc gagcaggcct
     7621 ccacatcgac tacgtgtgct cggatgtttt gtctgcccat gaggcggtag aggaacgctt
     7681 cgacattgtg tacacctcgg agggtgccct tgcatgggtg cctgacatac gccggtgggc
     7741 tcatgttgtc gcttccttgc tgaaaccagg cggcactctg gttgtacgtg acgtgcatcc
     7801 tcttgtggga acgttgaagg acccggtgca atgtgacgcc ctcgaacttc atttcccgta
     7861 ctttgaaacc cgtgagggaa tcacatggga cgacgactca agcgaagccg actacgcagg
     7921 ctcttctgtg accccaggca agaacgcgac ggtggagtgg aaccactcac ttgggcagat
     7981 tgtcaatgcg ctcagtgacg agggcgtctt tgttaaacgc cttgacgaga ttgatgagtt
     8041 attcttcccg atgtcgcccg atatgaaacg gtgcggaccc agcagctgga agctaccgga
     8101 atccgcaccg acatgtgccc ttcctctgtc attcagaatc gtggcaactg cagatctcac
     8161 atcgtgttga cgatcagacc gatgtgcgtg tagaagttca ggcatccgaa taggccgatt
     8221 gcaacgccgc atgccagcca cagccacatg acagcgttaa gaatgccgcc tccacgcgat
     8281 tcagatgtgc cttctttatc agcgcggaac acgccgattg ggaacaggac gcagcccaaa
     8341 ccgatgacaa agaagaacag tgacatgaag atcgcttcga accacggcca ctgtgcaaac
     8401 caaccggaaa tgggctcctg cgggggagcg gtgaagagtc ggtacatcac gccggcgaag
     8461 gcgatgcccc acagtcccaa tcccagtccg ccggcgaaaa tcgacagcgg ctttgcggcg
     8521 tggagcagtt cgctcagagc cttctgtgaa cgggcaatgt ggtcacgctg cttccagaga
     8581 tagaagcacg cgaacagtaa gagtgatcca aagcccaggc aggtttcacc gaagatcaca
     8641 ttgtcgtagg cgaaaccgcc agcggccagc ggccacgtcg tcgtcatgtg caagccggtg
     8701 gttgtcaaga tcaagccaag agcaccgaac gccatggcgt atccgtcgac ccgcacggca
     8761 gtcttgccgg agttcgagcg aacttccctg aagaacatcg caagcccgat gagcgctgca
     8821 ccggctgcga ctgccattaa cgtgttgtag gtcggcatgc tcggccaatc gatcatgccg
     8881 gggctttcga cacctctgaa aaagtcgtcc atctattctt ttctttcctc gacccatgtc
     8941 tccacacaaa atggagccgc gccgtctgcg cagtggggac actacgatgc taacaggctt
     9001 tcacggcgtg gcactggaat agtcggcgta gacgcgtcat aatgggtgta acgccacgaa
     9061 tcagcgtgtc tgtttccggt tgagaacgta ggggaagacg attctcacgc gaaatggagg
     9121 tcacgatgag taggtcttac acccgtggtg tacttttcgt gcactcaact ccgccagcgc
     9181 tgtgtccaca catcgagtgg gccgttggaa cagcgctcgg acaggaagtg cacctgcagt
     9241 ggactgatca ggatgctgca cccgggatgg tacgctccga attctcatgg gtaggccaga
     9301 ccgggtctgg cgcccgactc gcgtcggcac ttcgcggctg ggaacacctg cgttacgaag
     9361 tcaccgagga agccaccgcg atcactgacg gtggccgctg gtctcacacg ccgtcactgg
     9421 gcatcttcca cgcccaaatg gacacggcag gcaacgttgt cgtgccggaa ggaaggattc
     9481 gcgcagccct cgacgaatca cattccccga cagagatgat cgacaaactc aatcttgcgc
     9541 tcggacaggc gtgggatgat gagctcgaac cattccgcta tgccggtgcc ggagctccgg
     9601 tgcgctggct caaccgcgtg gggtaagaca tgggatcgat cggcgaccag cttggcatcg
     9661 acttgaccga actcctcgac atggacgaac cgcctcagag cgatcaggag gacaacgata
     9721 cggtcggtga agccgtcatg aacgcactgc tggaagaaac ctccatcgaa ccagaccgga
     9781 tgcgcgcaga cctgacactc gaaggtgacc tcgacctgga caccctcgga cgctactctg
     9841 tgatcagcca aatcgagcac gaactcggca tcaccttgat cgaccgggac gtggatgcac
     9901 tcacaacggt cgaggacctg ctcaacctag ctcgctcgac gtcctgaacc gcacacgagc
     9961 cctcccgaac ccgataggct ggatatgagg aggatcggac atgacgatca acggcacgtt
    10021 gacgcccacc gcgcggcgcg tcacgattcc aacatgggtg tgcaaagtcg tcatggcaat
    10081 cacaggcctg atcatggcgg cgttcgtctt catccacatg gtcggcaacg tcaagatcct
    10141 gaccgatcct gctcagatgg atcactatgc gcagtggctg cgcacgatcg gtgaaccggc
    10201 tcttccgtat gggtccgttt tgtggatcct gcgcgtgatc ttactgtcgt gtgttctgct
    10261 gcatatctgt ggcgcactca tcttgtggcg ccgcggcgcg ttgacccaca cgcccggtgt
    10321 gcgcaggctg aagcatcgcg gctgggctgc aaagctcatg cttccgaccg gacttgtcct
    10381 cattgccttt atcgtgatcc atatccttga cctcaccatt ggcacagtgg tcgaatcggc
    10441 cgctttccgc catcccgact ctcgtttcta cgccgctgcc aatgtggtgg catcgatgag
    10501 caggcctgtc atgttcgcgg catatgtcat cgcccttatt gcgataggcc ttcacctcag
    10561 ccacggcatt gagcgagcct ggcaggatct cggtgggcgc tcaccacgta tcggcaccgt
    10621 tgtgcgcatc gctggctatg cgatcgcttt ggcagttgtg atcggagacc tcaccgtcat
    10681 cgccgcttcg cacatgggag cgatcagcgt cgccctcgcg cttccgctcg ctgccggacg
    10741 cacgcatctg cgcattgacg agggcgcccc tgttgacgcc catgaacctg aagtcgaacc
    10801 cgaacgcatg tgggacgaat ttgtctccca cgcgcgcctc gtctcacccg ggaacaggcg
    10861 tacattcagg gtggttgttg tggggaccgg tctggcgggc gccagtgccg cagcggctct
    10921 ggctgaactg ggctttgggg tagatgcgat cacaactctg gatacgccgc gacgctccca
    10981 ttcagtggca gctcaaggcg gtatcaatgc ggcgcgggca cgacgagtcg actcggacag
    11041 cgtgcagcgg ttcgtcaccg acacgattaa gggcggtgat ttccgcgcca gagagtctga
    11101 agtatggaga ctgggtattg aatcggcgcg cgtcatcgac cacatgaacg cgctgggtgt
    11161 gccgttcgcc cgagaatatg gcggatcgtt atccacacga tcatttggcg gcgtgcaggt
    11221 ttcgcgaacg tactactcgc gagggcagac gggccagcaa cttcaggtgg cagcgtcctc
    11281 gtccctcatg cgtcaggtgg ctgcaggccg cgtgacgtta tgggtgcgcc acgaaatgct
    11341 cgacgtcgtc gttgctgacg gccgggccgc cggtgtgatc acgcgtgaca tgatcaccgg
    11401 acgcacccgc ttccatcccg cacacgcagt tgtgattgcc acaggcggat acggcaacgt
    11461 ctactactat tcgacgctgg caaagaactg ctcgacaaca ggcatatggc gagctcaccg
    11521 tgccggcgcc gccctcgctt caccgagcat gatccaattc caccccaccg cattacctgt
    11581 ctcattcccg tggcaatcca agaccacgct catgagcgaa tctctgcgta acgacggacg
    11641 catctgggtg ccacgcagcc ctggcgatga ccgagacccg aacaccattc ccgaagagga
    11701 acgcgactac tacctggagc gcaagtaccc cgcgtttgga aacctcacgc ctcgcgacat
    11761 tgcctctcgc gctgcgcgcg agcagatcga atcggggcat ggggtcggtc ccgaacgaaa
    11821 cagcgtgtac ctggatttta gggacgcact ggagcgggtg ggccgacgcg tcatcgctga
    11881 gcgctacggc aacctccttg acatgtacct cgatgcaaca ggggaggacc cctacactcg
    11941 ccccatgcgc atcgctcccg gcgcgcattt cacaatgggt ggcttgtggg tcgacttccg
    12001 cctcatgacc accatcccgg gactgtttgc agccggcgag gcgaacgcgg cctaccacgg
    12061 ggccaaccgt ctgggagcca attccttgct tgccgcctgc gtcgatggtg ctttcacaat
    12121 cccgcgcaca gtacccgact atttggcagg cattttaggc caggagttgc tctccgtcga
    12181 tgattcccgc gtgatcgctg cccgtgaggg ggtcgaatcg cgactgcagg gcctgctcca
    12241 catcgatgga gctactccga cggacagttt tgcccgcaag ttgggcgata tcatgtacca
    12301 ggggtgcggc gttgtgcgca gtaaggagag cctggaggct gcgctcagcg acatcgacgc
    12361 actccaacag cgcatgggtg ccgacctgcg tgtcagtggc gagacaggac acttcaacac
    12421 cgacttggtt gcagctgcca ggcttcagga cagcattcag atggccacac tcatgtgtgt
    12481 ggacgcgtgg catcgcgagg aatcctgcgg cgcgcacttc agaagtgaat accagacgga
    12541 gcagggggag gcgcagcgcc gcgacgacca gtggatgaac gtatccgcct ggaccactga
    12601 cgggtggcat gacctgagga cagatggcgc agctcccttg gcaattacct gcactcacca
    12661 cgccgaagag ctgacgttta ctaccgtccc cctggcaacg aggaactacc aatgaaactg
    12721 atcgtcgacg tgtggcggca aaaagccccg gaagctgtcg gaacattcca ctcctacgaa
    12781 ctggacgggt gcgatgaacg catgtcgatt ctggagctcc tcgatcacct caaccgcaac
    12841 ctgagttccc gcggcgtcga gccggttgcg tttgattcgg attgccgcga aggaatctgc
    12901 ggtgcatgcg gcattcaagt tgatggaagg ccccacggat tcagtgagaa tctgccggct
    12961 tgcatgcaga gggtcggcgc tcatgccgat ggcacgcatg tgcgcctgga accgttgcga
    13021 tcgggcgcct ttccagtgat ccgtgacctt gtggtagatc gcagtgtcct cgaccggatc
    13081 acgatggcgg gaggatttgc ttccgttgat accggtctgg ctcctgatgc ggacgcgatt
    13141 ccgattcgtc atcaagatgc cgaaggtgca cttgacctgg ccgcgtgtat cggctgcggc
    13201 gcgtgtgttg cggcgtgtcc gaacggctca gccgcgttgt atgcgggtgc acggatgggt
    13261 cacctggcag cgttgaacat tccggggttg gagcgggcag agcgtgcccg gcgcatgaat
    13321 gaggcgatgg atcagtactt tggctcgtgt tctggctacg gcgaatgcat cagagtgtgt
    13381 cctgcgaata ttcctttcga cgttgttgcc gttgcctcac atgaacgtct cagggcacta
    13441 tggtcgaggt ggcctcagcc tcgctaaagc accactacta tagacattga gatgagatgc
    13501 ccgacgatgg gctgacatga acggaggata ttgtgggaaa tcggtccgaa gaagatcttt
    13561 tgggaagtcg cgacgttccg caggaagcct actggggtat ccactccttg cgcgcgcagg
    13621 aaaactacca gatttccggt aggacgatca atgaagtgcc tgagctgatt cgggcattcg
    13681 ctcaggtcaa gaaagccgcc gcgctggcga ataaggattt gcgagtgctc aagcccgcca
    13741 cggcagatgc aattgtgcag gcctgcgatg ccatcatcga cgagggcgcg tgcctcgacc
    13801 agttcccgat cgaccagttc cagggtggtg cgggcacatc ggtgaatatg aacgccaacg
    13861 aggtgatcgc caatctcgct ctcgagatga ccggtcagga gcgagggcgc tatgatctga
    13921 ttaatcccaa cgacgatgtc aaccactccc agtccaccaa cgacacgtat cccacagctt
    13981 ttcgactggc cgcctacgag aaggtcgacc agctgcggca cgccgtgaat gatctggccg
    14041 acgcgtttga gcgcctcggt gcccgctatc agcatgtcct cactatgggg cgcacacagt
    14101 tgcaggatgc cgtccccatg acgattggtc aggaaatgac cgcgttcggc gtgactttgc
    14161 gtgaagagga cccacgtctg gtcaacgtag ccaacctgct tctggaaaca aacctgggcg
    14221 ccactgcgat tggcactggg ctcaatacgc ctccgggcta ccagaaggca gtggtcgctc
    14281 atctgcgtga gatcacgggc ctggacgtga cagcctccga agacttgatc gaagcgacat
    14341 cggatgccgg ggcgtatatc tccatgcatg ccacgatgaa gcgcaccgct ggcaagctgt
    14401 ccaagatctg caacgacctg cgtctgctct catcgggtcc gcgagccggc ttgaacgaga
    14461 tcaaccttcc gcaaagggct gccggatcct caatcatgcc cgcgaaggtc aacccggtga
    14521 tacccgaggt ggtcaaccaa gtctgcttca aagtcatcgg caacgatgtg acggtcacga
    14581 tggcagccga ggccggccag cttcagctca acgtcatgga accggtgatc gcccagtgca
    14641 tgtttgaatc ggccacgttg ctcacccacg catgtgacac gctgcgtgaa aagtgtgtgg
    14701 acggtatcac cgtcaacgaa gaaaactgcc gaaacatggt gatgaattcg atcggtatcg
    14761 tcacctattt caacgatgtc atcgggcatc atgccggtga cgtggtgggt aaacgagctg
    14821 cggcagaaaa caagaacgtc ggtgatctga tcgttgagat gggcttcctg tctcaggaac
    14881 aggtcgatga gatcctgtct ccggagaacc tggcgaaccc gcagtatcgt ggcgccaaga
    14941 tcagcgatga tcctgaaacc cccaagcagg cgtcaagtaa gcactagcgc gtaattctgc
    15001 caattgcaga cacacgaaga cgccctcgtc actctcactg agtagcgatg agggcgtctc
    15061 cacgtctgcg ttcacatctt attcgtctga agctgcagcc tcatcggcac cgatgcgcac
    15121 attgtgcagc tggtacttct cgatggcctg ttcgacgact gcgcggtcaa cctggttttg
    15181 atcggccagt gcctgcagcg tgcgcaccac cattgattct gcatcgatgt ggaagtagcg
    15241 tcgtgctgcg cggcgcgtgt cggagatgcc gaagccgtct gcgcccaacg tgtacaggta
    15301 gccgggaacc cacggacgga tctgatcaat gatcagggca tcgtaatcgg acgtgccaat
    15361 gaaggggcct tcagagcccg acaacttggt tgtcaggtag gcgtagcgcg gatcctcatt
    15421 cggatgcagg aagttgtgct cgtcagcttc cacgccatcg cgacgcagtt cgttccatga
    15481 cgtcaccgac cacacggcgg cgtccacgcc ccagtcctcg gccaggagct tgcgggcctc
    15541 acgtgcccac ggcaccgcca cacctgatgc caaaagctga gccttcgggc cctgccctgt
    15601 atggtcatca accttgtaga tgcccttgat aatgccgtcc acgtccacat tttcaggttt
    15661 tgcgggctga tgaatcggct cgttgtacac cgtcaggtaa tacatgacat tcgggtcacg
    15721 cgtatccgag ggatcgtgct cgcagaacat gcgcttaatg ccatcccaca tgatgtaacg
    15781 gatttcgtag gcgtaggcgg ggtcgtacag cacgaaaccg tggttggctg cacccaggat
    15841 cggggaatgg ccgtccaaat gctgaagacc ctcgccggtc agggtggtac gtccagctgt
    15901 cgcgcccacg acgaagccac gagtcagctg gtcggcagca gcccagaact ggtcgccggt
    15961 gcgctggaaa ccgaacatcg agtagaagat gtagaacgga atcatcggca ggttgtgcgt
    16021 cgcatacgag gtgcccacga cctgcaaggc agccgcagat ccagcctcgg taataccggt
    16081 gtgcatcacc tgcccctgtt cggattcctt gtaggacagc atcatgtccg cgtccacggc
    16141 agtgtaattc tgaccgtgcg tgttgaagat cctggctgac gggaagatag cgtccagacc
    16201 gaacgtgcgt gcctcatcgg gaatgatcgg cacgatgtgc cgaccaatat tcttatcacg
    16261 aagcaggtct ttgagcagtc ggaccagtgc cattgtcgtg gccacttcga gttttcctga
    16321 gcccttcgac aaagcctcga acggcttcat cgcaggttca ggcaggtgtg catcgtcatg
    16381 ggcacgacgc tcaggcaggt atccgcccag cttctcccga cgctccttca tgtacagcaa
    16441 cgcaggatcg tctgccggtg gcatgtaata cggcggcttg tacggatctt tctcgagctc
    16501 ctcgtcgctg atcgggatct gcagacggtc acgcagcgcc ttcgcatcct ccagagtcag
    16561 cttcttcatc tggtgcgtcg agttgcgtcc tgcaaaatgc gtgccgagcg cgtatccctt
    16621 aatggtgtgc gccaggatga cggtaggctg tccggtgtgc tccatcgcag ccttgtaggc
    16681 ggcgtacacc ttgcggtagt catggccacc tcggcccaga gcccagatct gctcatcggt
    16741 ccagtccttc acgagcgcct tggttcgcgg atcacgtccg aagaagtgtt cacgaacgta
    16801 tgcaccatct ttggccttga acgtctggta gtcaccgtcg agggtctcat ccatcaggtg
    16861 aacgagggca ttgtccttat ctgctgccag caactgatcc cagccgcgtc cccagatcac
    16921 cttgatgacg ttccagccgg cgcccttgaa gaaggcttcg agttcctgaa tgatcttgcc
    16981 attgccacgt acaggcccgt cgaggcgctg caagttggcg ttgacgacga aggtgaggtt
    17041 atccaggccc tgctgtgcgg cgagctgcag catgccgcgc gcttccggct cgtccatctc
    17101 gccgtcaccc aggaatgccc aggtgtgctg ctgagaagtg tccttgatgc cgcgcaactg
    17161 taggtagcgg tcaaaccacg cctggtagat tgcctcggcc ggtccaagtc ccagtgacac
    17221 ggtggggtat tcccaaaagt tgggcatttg gcgtgggtgg gggtaggaag gtagtccgcc
    17281 gtccacactg acctgctgac ggaatccgtc catctcttct tcggtcaggc ggccttcgag
    17341 gaatgcgcgt gcgtaagggc cgggggaggc gtgtccctgg aagaagatgt ggtcgccgcc
    17401 gcccgggtgg tctttgccgc ggaagaagtg gttgagaccc acttcgtaca gggtagcgac
    17461 tgatgcgtaa gaggagatgt ggccgcctac tccgacaccg gggcgctgag cgcgcgtgac
    17521 ctgaacggcg gcattccacc tgatccagcg gcggtactga cgctccatcg cttcatcgcc
    17581 ggggaagtag ggttcctggt caacggggat cgtgttgacg tagggcgtgg tgtattcctg
    17641 aggcagctgc acatcgcgtt tgcgagcctc gtccatcatg tgcagcagga tgtagcgtgc
    17701 gcgaggtccg cctttttcat cgatcaggct ggtgagcgag tcgatccatt cctgggtttc
    17761 gtcaggatcg ttgtccggaa tttgactgag caatccgttg atgacgggat gcttttggtt
    17821 tgtgctcaca gatacccctt tttatctcgt gctgacagac ctgtaggtcg ccaatgtcct
    17881 ggtggttcta ttctcacccg aaagtcccag atttgcgact tctttagggc ttaagaccca
    17941 tgagaatcgc ctcaattttg attcattgac gagggtgacg ccttccgacc gtactcgcag
    18001 gtcccgtcaa gccacatcgg cggcgacttt cggcgcaaat attcttccca ggtgcagatc
    18061 tgctctacta tagtgccgtt agatagttca cgagcccagc gggttcgcgt gtggaaggtg
    18121 gttacacaac gtggcgatca gcctcggatt cacccaaaat caggttgtcc aggaattcta
    18181 cgtagacgat gacagcgatg aagctgttcg cgatgctgtt gcacgcgaga ctggtcacga
    18241 actggtcgat gtcgattatg gcgacgttgt cgacggcgca ctggtatggt ggcgcgctga
    18301 cgacgctgaa gaggaagacc tcggtgacgt tctggtcgat gttgcgtcaa accttgacga
    18361 cggcggcatg atctgggttc ttttccccaa gccttctgat ccgaacactg tgcccgtggc
    18421 ggacattgcc gaagcagcca gtgtggcagg tcttcattct acgtccgcgt tctcaatggg
    18481 ggacacgtgg accggaatct gcgtcacggc tcgtccgcgc gcacaccggt aagacatctc
    18541 acgcacgtct caagtgcgtc tgcgtacctg tgtgcgttaa agtatccctc gtgccacgtc
    18601 agtggcacgt gtcgggcctg tagctcagtt ggccagagcg ctgcgtttac accgcagagg
    18661 tcgtcggttc gagaccggcc gggcccaccg ttaaagcgcc agtagcgcgc gtaccacagt
    18721 catgacaccg tgatcaatat ttgacggcgc gcggtatcgg gctcgtgctg tcacatccgg
    18781 atgagcgtta gccatcgcgt acgaatagtc ggcatggtcg aagagctcca ggtcgttcag
    18841 gaagtcgcca aacacaaccg tgtgctccgg accgatcccc agcgattcct gcagggcagt
    18901 caaccctcgt cctttattcg ccacaggatt catcatatcg acccagtggc gcgaagattc
    18961 tgccacctga tgcgattgac gcaagtgggg aacctgatca tcaacgaagg cagaaatatc
    19021 cgtgaagtca tacgttgcga gtttcaggac gttatcgtgc gccgcggcct gcttcaagtc
    19081 gtcgacgact tccagttgtg catagtattt gtgggcttca gcgtaaaact cggcatctgt
    19141 gcgttcaacg tacgcgctgt tctgcccgca cacgaccaga ccgaggttgt agcttccgtc
    19201 agagctcaca cgccgcgtca catcgatcat ttcattgact gtcggcatgt cgatgcaagt
    19261 ggtcgacaca acctgcccgt ggaacgtgac gatggagcca ttttcagcaa tgtaggagtg
    19321 accggcgtct gtgccggaaa acatggtgtc gagggtggcg agctgacggc ctgacgcggg
    19381 cacgaacgca atgtcacgta cagccagttc atgcatgagc ggccagaact cgtccggtag
    19441 attcgagttg ccatccagca gcgtcccgtc catgtcgctg gcgatcagtc gaatgtcaat
    19501 tggcccatcg ggcagtgtca tcatgggcgt atcgttcacg tcggctctcc gttcttgtcc
    19561 ggtcatgact gtatcatcga ccggcctccc gcacgggtca ccctcgtcaa ttcactcctt
    19621 catgcgcgtt gcgtgacgac gctgcacata gcagatcgac agatagatgc catacatgcc
    19681 gaaaacaaca gtcaggacga caaaccagcg ccaagtcagg taggccatca gagcccaaaa
    19741 agcggcgaac gcaaacgtcc atataacctg cgcacccagt ggcagcttct tcgtcgccaa
    19801 gagaggcgcg acgggcagtt gattcgaatt ttcgcgtcga gacatggcat cctcacctag
    19861 tagcgaatga aaggtacgtt atccgcctgt tcgaccgaag tcaagagtaa atagagcatc
    19921 gccctgagtt tatttcctgc gccgctcccg cacgcgcaca gatatctgaa cgggggagcc
    19981 ggcgaaaccg aagtcctcac gcagacgcct ctcaatgaaa cgtcgatatc cggggtcgag
    20041 gaaaccggtc gtgaagagca cgaagcgtgg gggagcggat gacacctgcg ttccgaacag
    20101 gatcctgggc tgtttgccac cgcgcagcgg atgcgggtgt gcggccacaa gctgccccag
    20161 aaaagcgttc agcttacctg tcgagattcg tgtttcccac ccggcaagag ccgtatccaa
    20221 cgcctgcacg attctgttcg tatgccacgt cgttgccgcc gaaatattga tgcgcggcgc
    20281 ccacgcgacc tgcacgagtt cgcgttcgag ttcagatttg agttcctttt ggcgttcctc
    20341 gtccaccagg tcccacttgt tgttgacgat cacgagtgcc cgcccggcat caacaacctg
    20401 ctgcacgacg cgcacgtcct gctcggtcaa tacttccgag gcatcaaaaa ggacgagggc
    20461 gacctcggct ttttcaatcg cagcctgtgt tctgatcgac gcgtagaaat cagctcccgt
    20521 tgttcggtgc attttgcggc gcacaccggc cgtatccaca aattgccact ggcggtcgcc
    20581 caaagtgacg atctcatcga ccgggtcacg cgtagtgcca gctgttgagt ctacgacgac
    20641 gcgctcatgt ccaacgagcg cattgagcag tgaggacttg ccgacgttcg gtcgtcccac
    20701 cagagccacg cggcgaatgt tgggatcgcg tggttgaccg gctcgtgccg agcgctcagg
    20761 gagaactgcc agcactcgat ccagcaggtc acccgtgcct cgaccgtgca aagcggagat
    20821 ggcgtatggt tcgcccatac ccaaacccca caggtaggca gcgtctgctt cctgcatggc
    20881 ggaatccacc ttgttagccg ccagaatgac cggcttgccg ctgcggcgca gcaactccac
    20941 gatacgttca tcagtggtgg taattcccac cgtcgcgtcg accaccagca gcactgcatc
    21001 tgacaggtcg atcgccacct cggcctggtc ggccacattg cgatccagtc cgcgcacgtc
    21061 gacttcccag ccgcccgtgt caacgacgag gaattcgcga ccagcccatt cggcctggta
    21121 ggtgacacgg tcacgtgtga cacccggcgt gtcctgcaca accgcttcgc gacgccccag
    21181 gatacggttc accagcgtgg acttgccgac gttgggtcgc ccgatcacag caaggaccgg
    21241 taagccgtcc atctcagtgc tggagggcag gtcgccctcg tgatcgtcaa ggatctgcaa
    21301 gtcggattca ctgagctcat agttgtccag tgacgaccgc atcgagcgtg cgcgggcttc
    21361 acctgtgtca atatcctgct cttcgctcac gtttgtcatc ctcgcttgcg gggttcactg
    21421 tattccagca cttcgcgtgc aaccggcacg tcattgtatc ggtgatagac atgatctatc
    21481 tcctgatacc actcggcacc cttcccggtg atcaggacga tgtcattcgc actggcgtcc
    21541 tgaatcgcgc accgtaccgc atcccggcgg cacgttgtaa cctccgtgac gttggtcagg
    21601 tcgggacgca cgttgcggat tccctccatc agctcggcgc gaattgccgc cgcgtcctcg
    21661 gttcgggggt tctcatctgt cacccacaac acgtccgcgt gtctcgccgc aacttcagcc
    21721 agcggtatgc gtttggaggc atcccggtca ccgtccgtgc caaagaccag gacgacgcgg
    21781 ccgccagcca gttcgcgcgc atccttgaga atccattcca gagcttcggg ggtgtgcgcg
    21841 taatcaacga tcacgagcgg ctgatcgtca cagtccggat tgattttctc catacgccca
    21901 ggaacctgcg gtgcccgctc gagggcagtg accgcctgat ctgaatccgc acccactgcc
    21961 gtcgccgctg cgattgccac agcgcagttt tgcacgttca cttctccgag taccgggctg
    22021 tgaacctggt gggtgtgccc cgccggatcg gtcagggaga aaacggtttg tgcggtctgc
    22081 ggatccggat gaatatcact gacgtgccag tctgcctgtt gcgagctcaa ggccgcaaca
    22141 gtcgtgatcg ggatcgtggc ctcacgtgcc agtcgctggc cccattcatc gtccacgcac
    22201 acgattccac gcagggcatg ctcgggcgtg aacagggatg ctttggcctg gaagtagtgc
    22261 tccatgtcgt gatagaagtc caggtgatcg tgctgcagat tcgtaaaaat ggcgacgtca
    22321 aagacaatgc cgtcaacacg attcaagctc aatgcatgag aggacacttc gatgaccgca
    22381 ttgtcagcgc cttgttgctg tgcgcaggca agaaagcgat gcaggaccgg tgcctcgttc
    22441 gtggtgcgcg tcgccaagat cgtcatgtca ccgatgcggg tttccacggt gccgcacagc
    22501 gcaggaacat cgtgtatggc gcccaacgcg gcgctgacca gataggttgt ggtggtcttt
    22561 ccgtttgtgc cggtcactgc tgcggtcgtc agtgactgat cggggtttcc gaccactcgt
    22621 gcagatacga acgctgccgc ctggcgaggg tcgtcgacaa ctgcaatagg gacgctcgcg
    22681 ccactgtcac gcaggatccg cgcacctttc tcatcagtga tgacgccggc cgcgccagcc
    22741 tcaagcgcac ctgcggcaaa ttcggcgccg tggtgggagt atccggggat tgccacgaac
    22801 acccatccgg catcaatgtc gctggaagag accgtcacgc cagtgacggg acagttggcc
    22861 ttgtcttcat tcacccattg atgaacatcg aggtcgcgga ccagttcacg aaaagtaatc
    22921 gctgatgtgc gaggacgcag ttcattaatg gtagtcatgg cgcacacttt actactcggg
    22981 cgcgccccaa tgcctcaact cgcgcgcgct cttacaatcg agacatgttt aacctcacgc
    23041 gatcccaggc acgtcagcgt gctcagacag tctcagtgtc ccacattgac gtgacggtgg
    23101 atctgacgcg tgcaggtgat cttgacgaga cacattatcc tgtcacctct gtgttcacaa
    23161 tgacgctcaa ccgtccctca acatttgttg acgtggtggg aacggtggac gaggttctgg
    23221 tcgatgacgc tccgcatgcg ttccaccatg acggatctcg ccttgacctt gatgaccttc
    23281 caatatcacg tccgatcacg ctcaccgtgc gcgcccactg cagcttttca cgcacagggg
    23341 aggggctcca ccgctatctc gatcctgaag atcaccgcat ctacctgtac acacagtttg
    23401 agcccaccga tgcgcgcagg gcctggccgt gtatggatca gcccgatatc aagccgcgct
    23461 ggacctt
//
