LOCUS       NZ_LR027880.1          23442 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR027880.1 Roseburia intestinalis L1-82 chromosome 1, complete
            sequence.
ACCESSION   NZ_LR027880
VERSION     NZ_LR027880.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:18:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3070868
            Orig. end    :: 3094310
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23442
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3080868:3084310]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13442
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23442
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23442
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="4"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             2093..2296
                     /locus_tag="ctg1_2830"
                     /transl_table=11
                     /translation="VKFQRIQDLRIDNDLTIKEISAMLGLHRDVYSRYEKGLRDFPIDI
                     LIKLADIYHCSIDYLVGRVDTK"
     CDS             complement(2392..2817)
                     /locus_tag="ctg1_2831"
                     /transl_table=11
                     /translation="LKKEEMTTVDFLLEAVGIVAALVYLGLQIYYGIVYGVSFTGIILN
                     AAILILVYVGLTLLARYPERVNNLPKEICSGKIRKYTIHMVRAVKLIFVLSLLFTSICD
                     VAGVQINKGYSLVTVALIVIVTVVYEGKIIKLLRGKK"
     CDS             complement(2789..3337)
                     /locus_tag="ctg1_2832"
                     /transl_table=11
                     /translation="MEYTHVKHTFLPVYNEESRILILGSFPSVKSRENQFYYGHPQNRF
                     WKVIAGIFKEPLPQTIDEKKDLLLRHRIAVWDVIDSCDIVGSSDSSIRNVVPNDMDLIL
                     SNAKIQGIFANGGKAHQLFVKYCHKEGMPPLGKLPSTSPANAAWNLERLTEEWKTAFET
                     YLEITEQEKTFEKRRNDNG"
     CDS             complement(3352..4326)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2833"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.7e-09, bitscore:
                     35.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLISTIMCLALLVGCLAGCGGNTQTGAADGKGLKMLLSLSQAD
                     TFRNVLVAQAQQTAEECGAQLDVFDAENSIENQVEHIKKAVSENYDVILCGPVDADTAL
                     ELEALAGDIPIVFFNSCPDESRLQAGKYIYVGSDEYVAGQYQAEYILDKFASADEINVV
                     LLKGPKKHSATKGRSESLKDTLNASGKKINYVFEDNADWEQDRAKEMFNIFLKTGQKCD
                     VAVCNNDSMALGIIDACDAAGISDVTVLGIDATADGCKAIEDGKMDFTVYQSAVGQGES
                     AVYAAIALATGKDVTTLEGATEDGLYVWVPFEKVDSSNVKNYE"
     CDS             complement(4342..6324)
                     /locus_tag="ctg1_2834"
                     /transl_table=11
                     /translation="MKKQKTVSIKAKLLGVIIPVVIAIVVVLVVAAYQISAGTIKKYSQ
                     NLLQSSVENQASQIEAWLNENLASFQMAKKIIEDLKPSDEELKTILDGYYGYNSNYPEG
                     LYVADSTGQLITASESTKKESDVTNSTWYKEGLTRVNMAVGSAYQNADGVNVISASGIL
                     NDGSDKVRVISADMTLDRIAIIVNSFIEMNDAEAFLVDKTSGVILANRDSSLISQTLGA
                     EGQSHFYQLTAEKAAEKDYNFATLDGNMTVFQEVDGTNWLLISYIPTSIVLSDLTQLRN
                     IMIVISVICIALLCVLIERVTHVVIKPVKEMTRVITAMTSGDFTVSIKTKGNDEIAVMS
                     QSVEKFIASMKQMISEMGNVSGKLKNQADSSKGVSGEMSSAAGIQSQSMSELNATVDQL
                     SVSVNEIAQNATQLAGVAADTKSDSDIVESRMQETVAVSEKGRKDMERVGEALSDIEVS
                     IHNLEEAVNKVGTASGEIVQIIQLIGDIADETNLLSLNASIEAARAGEAGRGFAVVAAE
                     IGTLAKNSADSVAHITELITEINNLVEDAVRQAGNSAQDISGSAELIHTAVDTFDTIFK
                     NIQETSTLIGNVVDKINQVDQVATNVAAISEEQAASSDEILATSESMLQQAKNISKNSD
                     QVEQEADNLAVSADQLAEQVKQFRI"
     CDS             6592..7602
                     /locus_tag="ctg1_2835"
                     /transl_table=11
                     /translation="MEHLIIPKDYHSELNLHDTQIAIKTVKDFFQNLLALRLNLSRVSA
                     PLFVDPLSGLNDNLNGIERPVTFDIKEQNGKEAEVVQSLAKWKRYALKKYGFDYGEGLY
                     TDMNAIRRDEDTDNIHSIFVDQWDWEKIIHKEDRNIETLKETVTTVYNCLRKTEKYMAI
                     QYDYIEEILPHDIFFITTQELEEMFPDNTPKEREYYITKTKGAVCIMKIGDTLENGEPH
                     DGRAPDYDDWSLNADIVVYYPVLDIALEISSMGIRVDKKALLSQLKKAGCEERAKLPFQ
                     KAIINEELPYTIGGGIGQSRICMFFLRKAHIGEVQSSLWPEAIAKECEKNGIQLL"
     CDS             complement(7838..8728)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2836"
                     /sec_met_domain="CN_hydrolase (E-value: 2.4e-51, bitscore:
                     172.5, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQIKAAAIQMKCDLEHKKNLQKAEQMIRKAAAEGANIILLPELF
                     EREYFCQQRRYDFYSYARTVEESEAVAMGVRLAKELGVVLPISFYERDVNNLYNSIACI
                     DGDGTILGVYRKIHIPDDHYYQEKFYFTPGDTGFKVFDTKYGCIGIGICWDQWFPETAR
                     AMALLGAELLFYPTAIGSEPILECDSMPHWRRCMQGHAAANLMPVIAANRIGREVVQPC
                     AENGGQESALEFYGSSFLTDETGEVILSASRDKEEILSQTYELDELRAKRLEWGLFRDR
                     RPEYYGIIAGEKNGR"
     CDS             complement(8806..10029)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2837"
                     /sec_met_domain="PAD_porph (E-value: 3.7e-115, bitscore:
                     382.5, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISKADCPKMIKDTTPVQDGFFMPGEFEQHQGCIMIWPERPGSW
                     RNGAKEAETAFSAVIRAIAASETVYVAAGKKGIDHAKAFAESLKKEENLHPVVVFEMET
                     DDSWARDVAPTFLVNRTDGKISDLTAAGNGTAQTGDDVKNSQVRGVNWSFNAWGGEVDG
                     LYASYEKDNAFAWNFCRKFEFDCYDAEPFVLEGGSIHSDGEGTLLVTESCLLSAGRNPS
                     LTKEQIEEQLKCYLGVEKVLWLPRGIYQDETNEHVDNVCAFLRPGEVVLAWTNNQNDPQ
                     YAMSKASFDYLSSVRDAKARKLIIHKLPIPDIPVCITKEELEGYEFEEGEDVREVGERL
                     AASYVNFYFSNNAVVMPVFGGENEESDLRAQQIMAKLCPDRKIIPVYARDILTGGGNIH
                     CITQQIPL"
     CDS             complement(10001..11134)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2838"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.1e-11,
                     bitscore: 42.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWQEIPTPCYVVDEKKLKQNLKILQNLEQETGCHVLLAQKAFSM
                     FSLYPLIGQYISGTTASGIFEARLGKEEMGKENHVFAPAYKEKDMEELVQICDHVIFNS
                     FAQYEKYQHYFLQQECTASAGIRVNPECSTQEGHEIYDPCGPGSRLGVVKSEFPDQLPE
                     GIEGLHFHTLCEQNADDLITTWHAFEEKFGSYLKQVKWLNLGGGHHITRADYQLDELKK
                     LICEIRRKYNVRVYLEPGEAIALNAGYLVTEVMDIVHNGMDILILDASAACHMPDVLEM
                     PYRPPLKDGYLPGEKPHTCRLSSMTCLAGDVIGDYSFAQKKQVGDRLVFEDMAIYSMVK
                     NNTFNGMPLPGIAVLREDGDVEMIKEFGYEDFKGRLS"
     CDS             complement(11222..12481)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2839"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.2e-42, bitscore:
                     143.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 7.8e-33,
                     bitscore: 111.4, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 3.3e-05, bitscore:
                     21.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLLIIGCGGVAGVAIHKCCQNSKTFTEICIASRTKSKCDALKE
                     KLEKTTDTVITTAQVDADNTEELIALIKKYQPDAVLNVALPYQDLTIMDACLACKVDYI
                     DTANYEPEDTDDKEWRAIYEKRCKEEGFTAYFDYSWQWAYREKFKEAGITALLGSGFDP
                     GVTSVFTAYALKHYFDEIETIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWENGH
                     WVETKPMEIKREYNFPQVGEKDMYLLHHEEIESLAKNVPGVKRIRFFMTFGQSYLTHMK
                     CLENVGMLSTSPIEYEGREIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGKKDGKEK
                     TIYIYNVCDHQECYKEVGSQAISYTTGVPAMIGAALVVDKVWDKDGVFNIEEFDPDPFM
                     DMLNQYGLPWVVDENPQTVA"
     CDS             complement(12579..13442)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2840"
                     /sec_met_domain="Spermine_synth (E-value: 1.1e-49,
                     bitscore: 166.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 9e-11, bitscore:
                     39.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWFSDYHTEKVKVSVKVQKQLFGLQTEFQRIDVFDSDEFGRFL
                     SSDGSIVFSEKDEFVYDEMIVHVPMAVHPHVKKVLVIGGGDGGVARELGYYDEIEQIDV
                     VEPDRVFVEVCKEFFPDNACGLSDERVTVYYEDGLKFLRMKHDEYDLIINDAIDPLGHT
                     AGLFTKEFYGNCFRALKDDGIMVYQHGSPFYDEDEESCRGMHRKASHSFPISRVYQAHI
                     PTCSSGYWLFGFASKKYHPLDDLDAKRWKERKIKTWYYTTNLHKGAFMLPRYVEDMLEE
                     EEGRKK"
     CDS             complement(13510..14964)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2841"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.2e-10, bitscore:
                     37.9, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.2e-128,
                     bitscore: 426.2, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKEQQMRAPVYEALEKLKKRRVVPFDVPGHKRGRGNPELVELLG
                     EKCVSLDVNSMKPLDNLCHPVSVIKEAEELAAEAFRAEHAFFMVGGTTSSVQGMVLSCC
                     KAGDKIILPRNVHKSVINALVLCGAIPVYVNPEVDVKLGISLGMQVSEVERAILENPDA
                     VAVLVNNPTYYGICSDLRSIVRVAHEHHMLVLVDEAHGTHLYFGENLPVCAMDAGADMA
                     SVSMHKSGGSLTQSSLLLTGKGVNWEYVSQIINLTQTTSASYLLMSSLDISRRNLALRG
                     KESFAKVAQMAEYARDEINSIGGFYAYGKDMVNGGSVYDFDVTKLSVYTRDIGLAGIEV
                     YDLLRDEYDIQIELGDIANILAYISIGDRIQDIERLVGALADIKRLYSKDPAKMLNTEY
                     INPKVLVSPQVAFYSQKESMPVRQTAGRICGEFVMCYPPGIPILAPGEMITPEIIEYIV
                     YAKEKGCSMQGTEDPEVENLNVLAKK"
     CDS             complement(15550..16377)
                     /locus_tag="ctg1_2842"
                     /transl_table=11
                     /translation="MLIGNHLSASKGYAAMGKAALALDANTFAFFTRNPRGGKAKEIDE
                     KDVEKFLNFAKEHEFGKIVAHAPYTMNLCAAKEDVRSFSKEMLLDDLKRMEYTPYNYYN
                     FHPGAHVGQGAEKGIALIAEALNEALKPEQTTTVLLETMAGKGTEVGRTFEELREILDR
                     VELNDKMGVCLDTCHVWDGGYDIVNDLDDVLNEFDRVIGLDRLKAVHFNDSMNDCGSHK
                     DRHAKIGEGKIGAEAMRRVALHPLLEGRPFILETPNDDEGYRREIQMVREWTR"
     CDS             complement(16461..18425)
                     /locus_tag="ctg1_2843"
                     /transl_table=11
                     /translation="MGQTDLRYLKSLSNQYPTIATAATEIINLQAILSLPKATEHFITD
                     VHGEYDQFLHVLKNGSGAIKRKIEDEFGNAISAAEKKAIATLIYYPEQKLEQVLKTEDN
                     LEDWYKVTLYRLIRICKNASSKYTRSKVRKALPKDFAYVIEELLTGRQEISDQEAYYNE
                     IIRSVIRTGRAAELVIAFCNLIRRLVVDHLHVVGDIFDRGPYPNLIMDTLMEHHSVDIQ
                     WGNHDVYWMGAASGSAACICNVIRISAKYGNLDLLEDGYGINLVPLARFAMKWYDKDSC
                     DCFKLDYREDEYDVHDAFLDEKMHKAITIMQFKLEGQLIKENPEFEMEKRLLLDKINIE
                     KGTVCVEETEYPLKDVSFPTIDWEDPYRLSEDEADVMERLVTAFVNCEKLQRHVRFLYT
                     QGSLYKVYNGNLLYHGCVPLNEDGTFTRVNVFGKEYAGKELYDVLEGYARKGYYAIDPK
                     EKKKGQDILWFIWENQNSPVFGKAKMTTFERYFIADKITHQEPKNPYYRLLEKEEVVNR
                     ILEEFGLEGAEAHIINGHIPVEAKKGESPVKCNGKLLIIDGGFSKAYQPKTGIAGYTLI
                     YNSYGLVLAAHEPFESVEKAVQDGSDIVSHTVLVQQVVRRKTVADTDIGKSLKESIHDL
                     EELLAAYRAGTIVEKNRAE"
     CDS             complement(18522..19289)
                     /locus_tag="ctg1_2844"
                     /transl_table=11
                     /translation="MIRAIMSGCNGKMGQVITGICKEDAEIEIVAGIDLYDGIKNDYPV
                     FPNISVCDVAADVIIDFSNAKAVDDLLVYSVDKQIPVVLCTTGLSEEQLKKVDGASKKV
                     AVLKSANMSLGINMLMELLKQAATILAPAGFDMEIVEKHHNQKLDAPSGTALALADSMN
                     EALGNAYTYTYDRSKERKKREKTEIGISAVRGGSIVGEHEVIFAGLDEVIEFKHTAYSR
                     SVFAKGAVQAAKFLSGKPAGFYDMGDVIKATIA"
     CDS             complement(19394..20284)
                     /locus_tag="ctg1_2845"
                     /transl_table=11
                     /translation="MSIFKGAGVAIVTPMKNNEEVNYDRLEQMIEYQINQGTDCIIIAG
                     TTGESSTLTTEEHAEVIKAAVKFAKHRIPVVAGTGSNCTREAIHLSEEAEKAGVDGLLC
                     VTPYYNKATQGGLIRYYTEIANSVKLPIIMYNVPSRTGCNILPETAAKLYHDVENIVAI
                     KEATGNVAQAAKTMYLTDGKLDLYSGEDGIVVPLMSIGAIGVISVWSNVAPKDVHDMCM
                     AFFDGDTKKAMEIQLKAQPLIEALFSEVNPIPVKKALNLMGMEAGPLRSPLTEMTDANA
                     AKLAETMKNYGIKLA"
     CDS             complement(20679..21314)
                     /locus_tag="ctg1_2846"
                     /transl_table=11
                     /translation="MADKMFENNQVSIVGEIVSDFRFSHEVYGEGFYMVDVAVNRLSNY
                     MDYIPLMISERLIDVNEDMVGQNIYVTGQFRSFNRHEEKKNRLVLSVFVRELEFLDEID
                     DEVKSNQIFLDGYVCKEPIYRKTPLGREIADLLIAVNRSYGKSDYIPCICWGRNARFAS
                     GFDVGGHVQIWGRIQSREYVKKLSETQTEKRVAYEVSVSKIDFLEELD"
     CDS             21441..23441
                     /locus_tag="ctg1_2847"
                     /transl_table=11
                     /translation="MEHVDKKTNVMTTFVRFLNKKILQNPTNMIKYIGWFFNLMLQLIH
                     FTQEREILYMKMKREDVRNIAIIAHVDHGKTTLVDELLKQSGVFRANQEVQERVMDSND
                     IERERGITILSKNTAITYKGTKINVIDTPGHADFGGEVERVLKMVNGVILVVDAFEGVM
                     PQTKFVLMKALELSLPVIVCLNKVDRPEARPNEVVDEVLELFMDLDASDEQLDCPFLFA
                     SARDGYAVREIGDLVNNKKDMTPLFETIIDYIPAPEGDPDANTQVLISTIDYNEYVGRI
                     GIGKVDNGCLKVNQEAVVVNHHEPDKQKKVRISKLYEFDGLNKVDVAEAKIGSIVAISG
                     IADIHIGDTICAPENPVAIPFQKISEPTLSMNFMVNDSPLAGQEGKFITSRHLRDRLFK
                     ELNTDVSLRVEETESPDCYKVSGRGELHLSVLVENMRREGYEFAVSKAEVLYHTDENGK
                     KTEPMEIAYVDVPDEFTGTVIDKLSQRKGELVNMKPITGGYTRLEFNIPSRGLIGYRGD
                     FMTDTKGNGIINTIFNGYAPYRGEIAYRKLGSLIAFESGESVTYGLFSAQDRGTLFIGP
                     GEKVYAGMVIGSCARAEDIELNVCKKKHLTNTRSSSADEALTLVPPKVLSLEQALDFID
                     VDELLEVTPESLRIRKRILDPTLRKRANMKK"
ORIGIN
        1 cctccctgcg cggcaaattc ttttccacgc gtgcatgatg tccgaagtac gccgtcctca
       61 atatgatagt acacgcgcac cggactgtta ttctttcccc agatctctat acttttgcta
      121 aaggtctttg atgcaatacc aactccgatc tttgcacttg cccccaccga tgcatacaga
      181 tatgcagcct gtgacgcgca gtatgtcggt gttccggaac tgtaccttac gtatttgatg
      241 ttcatacgtg caccggtttt tgcataaata tctccgctga caattccgag cgttgctttt
      301 gcagagagta caatacctgt ggtcaaatct gcttctgctg aaaaggaaaa tcctttttta
      361 tgactgtttc caactatacg gaatccgtcc gaatacgcaa atccggcttc aaattccttt
      421 tccacggtaa gcgttgcttc cccggaaaga ttatattcca ttgccagtgt caacatacca
      481 acaccgccga gcggcactgc ccctaacgtc agtgtgtggt taatatcttt aaatgcatcc
      541 ccttttacat tgcaggagta ttccatatct ccgctgactg aaaaataata gtcattatta
      601 ttcagactgt aatttacttt catgtttgaa atcacaacac ttactgtcgc tgtgacatca
      661 tctgagacgg aaatcgtttt atctgcacgc agggtattgt ttttatagga tatccccctt
      721 gtcatacctt ctgtgactgt aacaccattt gccacatatg tttcttcatc tgccggaata
      781 aattccgtca tatcaacatc cagttcgccc tgctggtcaa catttaaaac cgcgccatca
      841 tccgcatctg aggttgtaat atatgttgta gttccgtctg tccgtacact ttctgcctta
      901 tatgccatga caatatcgtt aacatacacg gcaaatgttg ttccctgttt gatcgtaacc
      961 ggacagtttt cgatcataac tattccatcc acatcaatag atacggctgt tccctttggt
     1021 acaacaacta ctccggacgc aaatgtacag gtattttctt ttccggtctc tatctgcgca
     1081 tctgccaaaa ccttttttgc atccgcgatc attgcatcat gctcttccgt ggtaagtgac
     1141 tgttccggga gaaatttacc ggcagcaacc gtaacccatc ctctgtcgat tgcgatctgt
     1201 gctgcttcct tatatgtaac atctgctgta tcctgataag tataactgtc tgtttccggc
     1261 acaaagccaa gcatcgtatt catggtctgc gctgcaaatt cacgcgtcac tgcatcttcc
     1321 ggtcgaaatt cttctcctgc ctcaagatcg atcattccga actcgcatgc caccatcaca
     1381 tcacgataaa acgaatcatc cgttgatatg tcactgtaat aattatccgg ataattatcc
     1441 tcatctaccg taagatcaaa taatgttacc agttcctgta cccagtcgat acggctgatc
     1501 tcatcacctg ataatgccct ttttaaaatc tcctctgtac tctccgtttc ttccgtaacg
     1561 ttctctgttt cagcctgttc tggctcttct gtgacattct ttgtttcagt ctcctctgtt
     1621 tcttctgtaa caaccttcgt ttctggctct tctgtctctt ccgtgacgat cgtcgtctct
     1681 ggctcttctg tctcttccgt gacaatttcc gtcccggccg ccccggactc ttcctctgcc
     1741 agacgtccgg cattatgatc ttcttcatct gcctggtctg tttctttttt ctctgtcact
     1801 gctgactttt catcatcctg ttctacagtc tgtgtttcca cagtcccttt ctctttaaaa
     1861 ctgttttctt cctgtgtctg ctgtgcattc cctgccacat ccgccagcag catttccggt
     1921 gctgccgtaa acgtcataca ggcacaaagc agccatgcta tcattcgttt tttcataact
     1981 ttctcctttc acagatatct cattccttac aatacgacca aacggtctta ttatgaatta
     2041 aattatagca ttttgattat aatttgtcta ttaagttaga ggagacactc acgtgaagtt
     2101 tcaaagaatt caggacttga gaatagacaa cgatcttact ataaaagaaa tctctgccat
     2161 gcttggtctg caccgggatg tttattcccg ttatgaaaaa gggcttcgtg attttccaat
     2221 tgacattctc ataaagttag cagatattta tcactgctca attgattatc tggttggacg
     2281 ggttgatacg aagtaatata atacacaaaa tgcctactcc gcagacattg atcactatat
     2341 ataaagaaaa gacgattcca ctcagaatcg tcttttcttt ataatatatg cttatttttt
     2401 cccacgcagc agcttaatga tcttcccctc atacaccact gtcacaataa cgatcaatgc
     2461 aaccgtcacc agactatacc ctttattgat ctgcactccg gcgacatcac agatactggt
     2521 aaataaaaga ctgagcacga agatcagctt gactgcgcgc accatatgaa tcgtatattt
     2581 tcttattttc ccactacata tttctttcgg caggttattt accctttccg gataacgtgc
     2641 aagcagcgtc agtccaacat atacaaggat caggattgcc gcatttaaaa taatcccggt
     2701 aaatgatact ccatatacga ttccatagta gatctgcagt ccaagataga ccagtgcagc
     2761 cacgattccc actgcttcaa gcaggaaatc aaccgttgtc atttcttctt ttttcaaatg
     2821 ttttctcctg ttctgttatt tctaaatatg tttcaaatgc cgttttccat tcctccgtca
     2881 gccgctctaa attccacgcc gcatttgcgg ggcttgtgga cggcagtttt ccaagcggcg
     2941 gcattccctc tttatgacag tattttacaa aaagctgatg tgcttttcca ccatttgcaa
     3001 aaattccctg tatttttgca tttgataaga tcagatccat atcgtttggc accacatttc
     3061 tgatggagct gtcggaagat ccaacgatat cacaggaatc gatcacatcc cacactgcta
     3121 tgcgatgtct tagcagaaga tccttctttt catcgatcgt ctgtggcaga ggttccttga
     3181 aaatccctgc aatcaccttc cagaaccggt tttgcggatg cccgtaatag aactggtttt
     3241 cccgcgactt tacagacgga aaggaaccca ggatcaatat cctggattcc tcattgtata
     3301 caggtaaaaa cgtatgtttt acatgtgtat attccatttt atacccgctt tctattcata
     3361 atttttgaca ttggagctgt ctactttttc aaatggtacc cagacatata aaccatcttc
     3421 cgtagcaccc tctaaggtcg tgacatcttt tccggttgca agtgcgattg ctgcataaac
     3481 agcactctca ccctgtccaa ctgcggactg gtatacggta aagtccatct ttccatcttc
     3541 aatcgctttg catccgtctg cagttgcatc gattccaagt accgtcacat cactgattcc
     3601 tgctgcatca caggcatcaa tgataccaag tgccatagag tcgttgttgc agacagcaac
     3661 gtcacacttc tgtcctgtct ttaaaaatat attgaacatc tctttcgcac gatcctgctc
     3721 ccagtcggcg ttatcttcaa agacataatt gatctttttc cctgatgcat ttaaagtatc
     3781 ctttaatgac tcagatcttc cttttgtcgc ggaatgtttt ttcggtcctt ttaacaacac
     3841 cacattaatc tcatccgcag aagcaaattt atctagaatg tactctgcct gatactgtcc
     3901 tgccacatat tcatccgatc caacataaat atatttccca gcctgaagtc tcgactcatc
     3961 cgggcagctg ttaaaaaata cgattggtat atcacctgca agtgcttcta actccagcgc
     4021 tgtgtcggca tcaaccggtc cgcataaaat cacatcataa ttctcactga ccgccttttt
     4081 gatatgttcc acctggtttt caatggaatt ttctgcatca aatacatcca gctgtgcccc
     4141 acactcttcc gcagtctgct gtgcctgtgc cacaagtaca tttcggaagg tatccgcctg
     4201 tgataacgac agcagcattt ttaaaccttt tccatcagct gcgcctgtct gtgtatttcc
     4261 accacatccg gcaaggcatc ctacaagcaa tgccagacac atgatagtac ttattaattt
     4321 cttcatcgca cgatctcctc tctatatccg gaactgtttt acctgttctg caagttgatc
     4381 tgcagaaaca gcaaggttat ctgcttcctg ttctacctgg tcactgttct ttgaaatatt
     4441 ctttgcctgc tgtaacatgg attctgatgt tgcaaggatc tcatcggaac ttgccgcctg
     4501 ttcttccgaa atagctgcaa cattcgtagc aacctgatct acctgattga tcttatcaac
     4561 cacattgccg atcagtgtgc ttgtctcctg gatattctta aagatcgtat caaatgtatc
     4621 aactgctgta tggatcagct ctgcactgcc ggaaatatcc tgtgcactgt ttcctgcctg
     4681 tctgacggca tcttctacca gattgttgat ttcagtgatc agctctgtga tatgtgctac
     4741 cgaatccgca ctgttctttg caagtgtacc aatctcagct gcaacaactg caaatcctct
     4801 tcctgcttcg cctgcgcgtg cagcctcaat tgatgcattt aaagataaca ggttcgtctc
     4861 gtcagcaata tcgccaatca gttggatgat ctgcacgatc tcgccggaag ctgttcctac
     4921 cttattaacg gcttcctcta aattatggat ggagacttca atatcagaaa gtgcctcgcc
     4981 gacacgctcc atatcttttc tgcctttttc agaaacagca actgtctcct gcatcctgct
     5041 ctcgacaatg tcactgtcac tctttgtatc tgctgccaca cctgcaagct gtgtcgcatt
     5101 ctgtgcaatc tcatttacag ataccgataa ctggtcgact gttgcattca gctcgctcat
     5161 cgactgtgac tggattcccg ctgcagaact catctcaccg gaaacaccct tacttgagtc
     5221 agcctgattc ttcaacttgc cggaaacatt tcccatttcg gagatcatct gtttcatgga
     5281 agcaataaac ttctccacac tttggctcat gactgcgatc tcatcattgc cttttgtctt
     5341 aatagaaacc gtgaaatcac cggaagtcat cgctgtgatc actcttgtca tttccttgac
     5401 aggtttgatt acaacatgag ttacacgttc gatcagtaca cagagcaatg caatacagat
     5461 cacactgatt acgatcataa tattacgaag ctgtgtcaga tccgaaagta caatgctggt
     5521 cggaatatac gatatcaaaa gccagttggt tccgtctact tcctgaaata ccgtcatatt
     5581 tccatcaagt gtagcaaaat tatagtcttt ctctgcagct ttctctgccg taagctggta
     5641 aaaatgactc tgtccttctg ccccgagtgt ctgggaaata agagatgaat cacggtttgc
     5701 caggatcaca ccgctggttt tatcaaccag aaatgcttcc gcatcattca tttcaataaa
     5761 agagtttacg ataattgcaa tacggtctaa tgtcatgtct gctgaaataa cacgcacttt
     5821 atcagatccg tcatttaaaa taccggaagc actgatcaca ttcacgccat ctgcattctg
     5881 ataagctgaa ccgactgcca tattcaccct ggtaagtcct tctttatacc aggtactgtt
     5941 tgttacatct gattcctttt ttgttgattc tgatgccgtt atgagctgtc ctgtggaatc
     6001 tgccacataa agtccctccg gataattact gttatagcca taataaccat ccagtattgt
     6061 ctttaactct tcatcactcg gcttcaaatc ctcaatgatc ttcttcgcca tctgaaatga
     6121 agcaaggttt tcattcagcc atgcttctat ctgggatgcc tggttctcta ccgaagactg
     6181 cagtaaattc tgggaatatt ttttgatcgt ccctgcagat atctgataag cagccacaac
     6241 aagtaccaca acgatcgcaa ttacgactgg tatgatcaca ccaagtaact ttgccttaat
     6301 cgacaccgtt ttttgttttt tcataagctg tcctctcttt tttacataaa atttacaaca
     6361 taaattataa aatcttcgtc gtttttcgtc aatatgtatc acaaaccgtt ttcgctaaaa
     6421 tttatattgt atacatgtat ttttcaagaa atcgtatgat cttttcttga aaatgagacc
     6481 tgctgtgcta taataaatta gtgtgccatt ttctttttca tacatatatc aggcacacgg
     6541 gattggtatc atgccgctgc atgcggttta taccagagag gagaacctta gatggaacat
     6601 ttaatcattc caaaagatta tcattcagaa ttaaatctgc acgatacaca gattgcaatc
     6661 aaaacagtaa aagatttttt ccagaacctg cttgcacttc gtctgaatct gtcccgcgtt
     6721 tcggctccac tttttgttga tccgttatcc ggtctcaatg acaacttaaa cggtattgaa
     6781 cgtccggtta ctttcgatat caaagagcag aacgggaaag aggcagaggt tgtacagtct
     6841 ctcgcaaaat ggaaacgcta cgcattaaag aaatacggtt tcgactacgg tgaaggcctg
     6901 tataccgata tgaatgcgat ccgcagagat gaagacacgg ataacatcca ctctattttc
     6961 gtagaccagt gggactggga aaaaatcatc cataaagagg atcgtaatat cgagacatta
     7021 aaagaaacag ttaccactgt ttataactgc ctgcgcaaga cagaaaaata tatggcgatc
     7081 cagtacgatt atatagaaga gattcttcca catgatatct tctttatcac gactcaggaa
     7141 ttggaagaaa tgttccctga caacacacca aaggaacgtg aatattatat tacaaaaacc
     7201 aaaggtgccg tatgtatcat gaagatcggc gatactttgg aaaacggaga gcctcacgac
     7261 ggacgtgctc cggattacga tgactggtcc ttaaacgcag atatcgttgt ttactatccg
     7321 gtacttgaca tcgcacttga gatttcttcc atgggtatcc gggttgacaa gaaagcgctt
     7381 ctctcccagc tcaaaaaagc aggctgtgag gagcgtgcaa aacttccttt ccagaaagcg
     7441 atcatcaacg aagagcttcc ttatacaatc ggtggtggaa tcggacagtc ccgtatctgt
     7501 atgttcttcc ttcgcaaggc acatattgga gaagtacagt cttccctgtg gccggaagct
     7561 atcgcaaaag aatgtgaaaa gaacggtatt cagcttttgt aacaggaacg ggcatatgct
     7621 ccgcagatat cctgtcatca acactgatgc ctgataaaaa acaggtatgt ttcaaatgtc
     7681 agcaatgagc tttccctgct ccctgctgac aaaaacatac ctgttttttt catctttctg
     7741 ttttttcagt cctgtgcggt ttccactatc ttccggtctt ttcagtcccg tgtgatttcc
     7801 actatcttcc ggtcttttca atcccgtctg gttctcacta tctcccgttt ttttctcctg
     7861 ctatgattcc gtaatattcc ggtcttctgt cccggaaaag tccccattcc agtcgttttg
     7921 cccgaagttc atccagttca taggtctggc tcaggatttc ttctttatct ctggaagcac
     7981 ttaagatcac ctctcctgtt tcatccgtca gaaatgagga accataaaat tccagtgccg
     8041 actcctgtcc gccattttcc gcacatggct gcactacttc cctgccgatc cggtttgcgg
     8101 caatgacagg catcagattc gcagccgcat gtccctgcat gcagcgtctc cagtgcggca
     8161 tactgtcaca ttctaaaatc ggttccgagc cgatcgctgt cgggtaaaac aataattctg
     8221 caccgagcag cgccatcgcg cgcgctgtct ccgggaacca ctgatcccag cagattccaa
     8281 taccgatgca accgtatttt gtatcaaaca ctttaaatcc ggtatctccc ggtgtaaaat
     8341 aaaatttttc ctgataataa tgatcatccg ggatgtggat tttccgatac acaccgagga
     8401 tcgttccatc tccatcaatg catgcgatcg aattatagag gttattgaca tcacgctcat
     8461 aaaagctgat tggaagcacc acgcccaatt cttttgcaag acgtactccc attgccacag
     8521 cttcactctc ctccacagtt cttgcatagc tgtaaaaatc atatctgcgc tgctggcaga
     8581 aatattcccg ctcaaaaagt tccggcagta aaatgatatt tgcgccttcc gcggcagctt
     8641 tgcggatcat ttgttctgct ttttgtaagt ttttcttgtg ctccaggtcg catttcatct
     8701 gaattgcggc tgcttttatc tgtctcatgc gtgtatcctt tctgttcttt ttatttttgc
     8761 acagtgaatt aattctccta tgcggaaagt tgtacaataa attccctata agggaatttg
     8821 ctgtgtaata cagtggatgt ttccaccgcc tgtcagtatg tctcttgcgt acaccggtat
     8881 gatttttctg tccgggcaga gttttgccat aatctgctgt gcacgcaggt cgctttcttc
     8941 gttttctccg ccaaatacag gcatgactac cgcattgttg gaaaaataaa agtttacata
     9001 ggaggcggcg agccgttctc cgacttccct gacatcttca ccttcctcaa attcgtatcc
     9061 ttcgagttct tctttggtga tacagaccgg aatatccgga attggaagtt tgtggatgat
     9121 cagctttctg gcctttgcgt cccgcaccga acttagataa tcaaaactcg ctttcgacat
     9181 cgcatactgc ggatcattct ggttattggt ccatgcaagc acaacttcac ccggtcttag
     9241 aaatgcacag acattgtcca catgctcgtt ggtctcatcc tgatagatcc cgcgtggcag
     9301 ccataaaact ttctccacgc caaggtaaca ctttaactgt tcttcaatct gctcctttgt
     9361 aagcgatggg tttctccccg cactgagcag acaggactcc gtgacaagca atgttccctc
     9421 tccgtcgctg tggatagaac cgccctctaa cacaaacggt tcggcatcat aacagtcaaa
     9481 ctcgaatttt ctgcagaaat tccatgcaaa cgcattgtct ttttcataag aagcatatag
     9541 tccatccact tcaccgcccc aggcattaaa agaccagttt acaccgcgca cctgtgagtt
     9601 ttttacatca tcacctgtct gcgccgtacc atttcctgct gctgtcaggt ctgaaatctt
     9661 tccatccgtt ctgtttacca gaaaggtcgg cgcaacatcc cgcgcccagg aatcatcggt
     9721 ctccatctca aagacaacca ccggatgtaa gttttcttct tttttcagac tttccgcaaa
     9781 tgcttttgca tggtcaatcc ccttttttcc ggcagcgaca tacactgtct cactcgcggc
     9841 gattgcacgg atcacagctg aaaacgctgt ttctgcttcc ttcgcgccat ttctccagga
     9901 accgggacgc tctggccaga tcatgataca tccctgatgc tgctcaaact cacccggcat
     9961 gaaaaatccg tcctgtaccg gtgttgtatc ttttatcatc ttaggacagt ctgcctttga
    10021 aatcttcata accaaactcc tttatcatct cgacatctcc atcttcccgt aagactgcaa
    10081 ttccgggcag cggcatcccg ttaaatgtat tgtttttgac catggaataa attgccatat
    10141 cctcaaagac cagacggtct cccacctgtt ttttctgtgc aaagctgtaa tcaccgatca
    10201 catccccggc aaggcaggtc atggaagaaa gccggcaggt atgcggcttt tcgcccggca
    10261 gataaccgtc ttttagcggc ggtctatatg gcatttcaag cacatccggc atgtggcatg
    10321 ccgccgatgc atccagaatc aggatatcca ttccattgtg tacgatatcc ataacctccg
    10381 tgacaagata gcccgcattt aatgcgatcg cctcacccgg ttccaagtag acccggacat
    10441 tatattttcg cctgatctca cagattaatt tctttagttc atccaactga tagtctgctc
    10501 ttgtaatatg atgaccgccg cctaagttca gccattttac ctgttttaaa taactgccaa
    10561 acttctcctc aaacgcatgc caggtcgtga tcagatcatc cgcattctgc tcgcagagtg
    10621 tatgaaaatg taatccttcg attccctccg gcagttgatc cggaaattca cttttaacca
    10681 caccaagcct tgatcccggt ccgcatggat catagatctc atgcccttcc tgtgtggagc
    10741 actccgggtt cacgcggatc ccggcacttg cagtgcactc ctgctgcaaa aaatagtgct
    10801 gatacttttc atactgcgca aaggaattaa aaataacgtg atcgcagatc tgcaccagtt
    10861 cttccatatc tttttcctta taagccggtg caaatacatg attttccttt cccatctcct
    10921 cttttccaag gcgcgcctca aagattccgc tcgccgtcgt tccgctgata tactgcccga
    10981 tcagcggata cagtgaaaac atggaaaatg ccttctgtgc cagaagcaca tggcagccgg
    11041 tttcctgttc caaattctgc aatattttta aattttgttt tagcttcttt tcatctacca
    11101 cataacacgg ggtaggaatc tcctgccatt tcatgataat tctccatttc tgcaaaaatc
    11161 cgctgcgcaa aagctgacaa atttaaaatt ttatccaacc cgtttcacac atattcttat
    11221 tttatgccac cgtctgcgga ttttcgtcca caacccatgg cagaccatac tggtttaaca
    11281 tatccataaa cggatccgga tcaaactctt caatattgaa tacaccgtct ttgtcccaga
    11341 ctttatcgac aactaacgct gcaccgatca tagccggaac acctgttgta taagaaattg
    11401 cctgggaacc gacttctttg taacattcct gatgatcaca gacattatag atataaatcg
    11461 tcttttcttt tccgtctttt tttcccgtaa agatacagcc gatatttgtt tttccaaccg
    11521 tgcgcggtcc taaagatgcc ggatccggaa gcagtgcttt taagaactgg attggtacga
    11581 tctccctgcc ctcatactcg atcggtgatg ttgagagcat tccgacattt tctaaacatt
    11641 tcatatgtgt cagatagctc tgtccaaagg tcataaagaa acggatccgc tttactccag
    11701 gtacattttt tgcaagggac tcaatttcct catgatgcag cagatacata tctttctcgc
    11761 caacctgtgg gaaattatat tctcttttaa tttccattgg ttttgtttct acccagtgac
    11821 cattctccca gtaagaaccg tttgcggaaa cctcacgcag gttgatctcc gggttaaaat
    11881 tggttgcaaa cggatagccg tggtcgccgc cgttacagtc taagatatca atcgtctcga
    11941 tctcatcgaa ataatgtttc agggcataag cggtaaatac actggtcact cccggatcaa
    12001 acccgcttcc aagcaatgcc gtaattcctg cctctttgaa tttttcacgg tatgcccact
    12061 gccaggaata gtcaaaatat gctgtaaatc cctcttcttt acagcgtttt tcatagatgg
    12121 cacgccattc tttgtcatcc gtatcctccg gctcataatt tgcggtatcg atatagtcta
    12181 ctttgcatgc aaggcaggca tccataattg ttaaatcctg atatggcaaa gcaacattta
    12241 acacagcatc cggctgatat tttttgatca gggcgatcag ttcctccgta ttgtccgcat
    12301 ccacctgtgc tgttgtgatg acagtgtccg ttgttttttc cagtttctct tttaaggcgt
    12361 cacatttcga ttttgttctg ctcgcaatgc agatctccgt aaaagttttg ctgttctggc
    12421 agcatttgtg aatcgcaact cctgcaactc cgccacatcc gataattaat aatcttccca
    12481 ttttaatctc ctttcctgcg ctgtcttttt gcgcatctca agtttgtgcc ggggcacaaa
    12541 tcttgcgtgt gaaaaaataa attttaattt aatttttatt atttcttacg tccttcttct
    12601 tcctctaaca tatcctccac atatcgcggc agcataaatg ctcccttgtg cagattggtg
    12661 gtataatacc aggtttttat cttccgctct ttccagcgct ttgcatccag atcatcgagc
    12721 ggatgatatt tctttgacgc aaacccgaac agccagtatc cggaagaaca cgttggtata
    12781 tgtgcctgat acacgcggct gattggaaag ctatgactcg ctttccggtg cataccgcgg
    12841 caggattcct catcttcatc gtaaaacgga cttccatgct gatataccat gattccgtca
    12901 tcttttaagg cacggaagca gtttccgtaa aattccttgg taaacagtcc tgcagtatgt
    12961 ccaagcggat caatcgcatc gttgatgatc agatcatact cgtcatgttt catccgcaaa
    13021 aatttcaatc catcctcata gtacaccgtc acgcgttcat ccgataaccc gcatgcattg
    13081 tccggaaaaa attccttgca gacctcgaca aatacacgat ccggctccac gacatcgatc
    13141 tgctctatct catcgtaata gccaagctct cgtgccacgc cgccgtcacc gccgccgatg
    13201 actaacacct ttttcacatg cggatgcacc gccatcggaa catgcacaat catctcatca
    13261 tagacaaact catctttttc cgaaaaaaca atactaccgt cggaacttaa aaaacgccca
    13321 aactcatccg aatcaaacac atcgatccgc tgaaactcgg tctgtaaacc aaataactgt
    13381 ttctgcacct tgaccgacac cttgactttt tccgtgtgat aatccgaaaa ccaaagttcc
    13441 atgatcttct cccttctttt gaaaaaatct tcttttcaca ggaatcttta tttttgctga
    13501 tctatgctgt tatttctttg caagcacatt cagattttca acttccggat cctccgttcc
    13561 ctgcatagag catccctttt cttttgcata aacaatgtac tcaatgatct ccggcgtgat
    13621 catctcaccc ggcgctaaaa tcggaattcc aggcggatag cacatgacaa attcaccgca
    13681 gatccttccc gctgtctgac gaaccggcat ggattccttt tgcgaataaa atgccacctg
    13741 cggcgacact aaaaccttcg gattaatata ttccgtattc agcatttttg ccggatcttt
    13801 cgaatacagc cgtttgatgt ctgcaagtgc acccacaagc cgctcaatat cctgtatccg
    13861 gtcaccgatg gaaatatagg caagaatatt tgcgatatct ccaagctcga tctgaatatc
    13921 atattcatcc cgcagcagat catagacctc aatgcctgca agcccgatat ctctcgtata
    13981 tacagacagt tttgtcacat caaaatcata gacactgcca ccgtttacca tatctttgcc
    14041 atacgcataa aatccaccga tagaattgat ctcatccctc gcgtactccg ccatctgtgc
    14101 cactttcgca aaagattcct ttcctcgcaa ggcaaggttt ctccgcgaaa tatcaaggct
    14161 cgacatcaga agataagatg cactcgtcgt ctgcgtcaga ttgatgatct ggctgacata
    14221 ttcccagttc acaccctttc cggtcagaag aagagagctc tgcgtcaggc ttccccccga
    14281 cttgtgcatg gagacagacg ccatatccgc cccagcatcc atggcacata ccggaagatt
    14341 ttccccaaaa tacagatgcg ttccatgtgc ctcatccacc agcaccagca tatgatgttc
    14401 atgcgccact ctcacgatag accgcagatc cgaacagatt ccatagtaag tcggattgtt
    14461 gactaaaact gctactgcat ccgggttctc caaaatcgca cgttccacct ctgacacctg
    14521 cattcccagt gaaatgccaa gtttcacatc gacctccgga ttgacgtaaa ccggaatcgc
    14581 tccacagagc accagtgcat taatcacact cttgtgcaca tttcgcggca aaatgatctt
    14641 atcccctgcc ttacagcagg aaagcaccat tccctgaacg gaggaagtgg ttccgccaac
    14701 cataaaaaat gcatgttccg cgcgaaatgc ctccgcggca agctcctccg cttccttgat
    14761 caccgaaacc ggatgacaga gattgtcaag cggcttcatg gaattgacat ccagactcac
    14821 acatttttct cccaacagct ctaccagctc cggatttccc cttcctctct tatgtcccgg
    14881 cacatcaaac ggcaccactc ttcgtttttt taacttttcc agtgcctcat aaaccggcgc
    14941 acgcatctgc tgctctttgt ccatgactaa aaaaatcccc cttggcttcc ataaaaatct
    15001 gcatgctctg cttttcatca aatgtttttc cctgacatta ccgtcaggct gaaaaacgca
    15061 aaaaaaagaa caggcatcca tcacctgttc ttctatcgtc gttatcatca tagtcatact
    15121 ttatgtaatc tatctacatt ctgcaaaaac tattttctcc agagtccgcg ttggcatctt
    15181 tgccagcaaa tatttgcgta tactactctt attgaccgtt tcacaagtga tattggattc
    15241 cgggtatcat ccccgtaatc aacttataaa atttgagctt ctaactcaat caataacgcg
    15301 gcttacaccg caatcggcag ttgccccgcc tgtccgtatg ggcttaacca atctcttggt
    15361 gggcaaacaa tagatccttt tccatctatt gtaacgaata tttgcatgaa aacaattttc
    15421 gcattcatgt gatttgaagt atagcataca cacatggcaa atgcaataac gtattctgta
    15481 aaattctggt attttctttt ttatttcatt ttaggatatt tttattttct attcaggttt
    15541 gcagcgatct taccgcgtcc actcccggac catctgtatc tcccgtctgt acccctcatc
    15601 atcgttcggt gtctctaaga taaacggtct tccttctaaa agcgggtgca atgcaacgcg
    15661 ccgcatcgcc tctgcaccga tctttccctc accgatcttc gcatgacggt ccttgtggga
    15721 gccacagtca ttcatgctgt cattaaagtg aactgccttc agccggtcga gcccgatcac
    15781 acggtcaaac tcatttaaca catcgtcaag gtcgtttaca atgtcataac cgccatccca
    15841 cacatggcag gtatcgaggc agactcccat tttatcgttt aattccacac ggtctaagat
    15901 ttctcttaac tcctcaaacg ttcttccaac ctcagttcct tttcccgcca tcgtctcaag
    15961 taaaacggtc gttgtctgct ccggtttcaa ggcttcattt aatgcttccg caatcaatgc
    16021 gatccctttt tccgcccctt gtcccacatg ggcacccgga tgaaaattat aataattgta
    16081 cggtgtatac tccatgcgtt ttaagtcatc aagcagcatt tcctttgaaa aagaacggac
    16141 atcctctttt gcagcgcaga ggttcatcgt atatggcgca tgcgcaacaa tctttccaaa
    16201 ttcgtgctcc tttgcaaaat ttaaaaactt ttccacatct ttttcatcga tttcttttgc
    16261 cttaccgcca cgcggatttc ttgtaaaaaa agcaaaggta ttggcatcta acgccagcgc
    16321 tgcctttccc atcgccgcat atcctttgga tgcggataaa tgatttccta ttaacatatc
    16381 aatcctcatt tctgcattgc gcttcgcgca ccttaatttt gtgcacaata atactcctgt
    16441 ctgtatatgc gaatgctctt ttattctgcc cggttcttct ccacgatcgt gcccgctctg
    16501 tatgccgcga gcagctcctc aagatcatgg atcgactctt ttaaactttt tccgatatct
    16561 gtatcggcaa ccgtttttct ccgcacgacc tgctgcacca gaaccgtatg ggatacgata
    16621 tcgcttccgt cctgcaccgc tttttctacc gattcaaacg gttcatgcgc cgcaagcacc
    16681 agaccataag aattataaat cagcgtatat ccggcaatcc ccgtctttgg ctgatatgcc
    16741 ttggaaaaac cgccgtcaat gatcagaagc tttccgttac atttgaccgg agactctcct
    16801 ttttttgcct ccaccggaat atgaccgtta atgatgtgcg cctccgcacc ttcaagcccg
    16861 aattcctcta aaatccggtt gaccacttcc tctttttcaa gcagcctgta ataaggattt
    16921 ttcggctcct gatgcgttat tttatctgca ataaaataac gctcaaacgt cgtcatcttt
    16981 gcctttccaa acaccgggga attctggttt tcccagataa accataaaat gtcctgtccc
    17041 tttttcttct ccttcgggtc gatcgcataa tagccttttc gcgcatagcc ctcaagcaca
    17101 tcataaagct cttttccggc atattctttt ccaaaaacgt taactctggt aaacgtgcca
    17161 tcctcattca gcggcacgca tccatgatag agaagatttc cattatatac tttgtaaaga
    17221 cttccctgtg tatacaaaaa acgcacatga cgctgcagtt tttcacagtt cacaaatgca
    17281 gtcacaagac gctccatcac atccgcctca tcttctgaga gacgatatgg atcttcccag
    17341 tcgattgtcg gaaaactgac atccttgagc ggatactcgg tttcctccac acacacggtc
    17401 cccttttcga tgttgatctt atcgagaaga agtcttttct ccatctcaaa ttccgggttt
    17461 tctttgatca gctgaccttc cagtttaaac tgcatgatcg tgatcgcctt atgcattttt
    17521 tcatctaaaa atgcgtcgtg cacatcatat tcatcttccc ggtaatccag cttaaaacag
    17581 tcacaggaat ccttatcata ccacttcatc gcaaatcttg ccagcggcac cagattaatc
    17641 ccgtaaccgt cctctaacag atcaaggttt ccatattttg cagaaatgcg gatcacatta
    17701 cagatgcatg ccgcactgcc cgacgccgct cccatccagt acacatcgtg attgccccac
    17761 tggatgtcca cagagtgatg ctccatcagt gtgtccatga tcagattcgg atatggtccc
    17821 ctgtcaaaaa tatccccgac cacatgcaga tgatccacaa caagccggcg gatcagatta
    17881 cagaacgcga tcacaagctc cgccgccctt ccggtgcgga tgaccgaccg gataatttca
    17941 ttataatatg cctcctgatc ggatatctcc tgtctgccgg tcaaaagttc ctcaatcaca
    18001 taggcaaagt cttttggaag tgctttccgc acttttgacc ttgtatactt ggaagatgca
    18061 tttttacaga tgcggatcag gcggtataag gtgactttgt accagtcctc caaattatct
    18121 tccgtcttta acacctgttc caacttctgt tccgggtaat agatcagcgt ggcgatcgct
    18181 tttttctccg ccgcgctgat tgcattgcca aattcatcct ctattttccg cttgatggca
    18241 ccggatccat tttttagcac atgtaaaaac tggtcgtact ccccgtgcac atctgtgata
    18301 aaatgttctg ttgcttttgg caggctaaga atcgcctgta aattgataat ctctgtcgcc
    18361 gctgtggcaa tggtcggata ctgatttgat aaacttttta aataacgcag gtcggtctgc
    18421 cccatagtat tcctcatttc tttttcacgt tcatttgctg cttttttatc ttatcatagg
    18481 aaatgagcgg gggcaaccaa cgttaattta ttgtcaatgc tctacgcgat cgtagccttg
    18541 atcacatccc ccatatcata gaatcccgcc ggttttccgg acaggaattt tgctgcctga
    18601 acagctcctt ttgcaaatac acttctggaa tatgcagtat gcttaaactc gatcacctca
    18661 tcaagtcctg caaagatcac ctcatgttct cctacgatgc tgccgccgcg cactgcagag
    18721 ataccgatct ctgttttttc tctctttttg cgctctttgc tgcggtcata agtataggta
    18781 tatgcattgc caagcgcctc attcatggaa tcggcaagtg caagtgccgt accgctcggc
    18841 gcatccagtt tctggttgtg gtgtttttcg acgatctcca tatcaaaacc ggccggtgct
    18901 aaaatggttg cagcctgttt taacagttcc attaacatat tgattccaag cgacatgttg
    18961 gcagatttta atacggcaac ttttttcgat gccccgtcca ccttttttaa ctgctcctca
    19021 gaaagtcctg tcgtgcagag tactaccggg atctgcttgt ccacactata taccaaaaga
    19081 tcatccactg cttttgcatt ggaaaaatca atgatcacat ccgctgccac atcacagaca
    19141 gagatattgg ggaataccgg gtaatcgttt ttgatgccat cgtagagatc gattcctgcc
    19201 acgatctcaa tctctgcatc ctccttgcag atccctgtga tcacctgtcc catttttccg
    19261 ttgcatccac tcataattgc tcttatcata ttgttttttc ctctcttttc tttatttaaa
    19321 gcaacaccgg aaacgctgcg aaccaacatt tccggtgttt tttcaaatct ggctttccgt
    19381 gttccactgc cccttacgcc agcttgatcc cataattctt cattgtttcc gcaagttttg
    19441 cagcattggc atctgtcatc tctgtgagcg gggaacgaag cggtcctgcc tccatgccca
    19501 tcagattcag cgctttctta acagggatcg ggttcacttc ggagaacagc gcctcaatga
    19561 gcggctgtgc ctttagctgg atctccattg cttttttcgt atctccgtca aagaatgcca
    19621 tacacatatc atgtacatcc ttcggtgcca cgtttgacca tacggagatc acaccgattg
    19681 ctccgatcga cattaacggt actacgattc catcctcgcc ggaatacaga tcaagctttc
    19741 catccgttaa atacatggtc tttgctgcct gtgcaacatt tccggttgcc tctttgatcg
    19801 caacgatgtt ttcaacatca tggtacagtt ttgcagctgt ctccggaagg atattgcatc
    19861 cggtacggct tggaacattg tacatgataa taggaagttt tacagaattt gcaatctctg
    19921 tgtagtagcg gatcagacct ccctgtgttg ctttgttata atatggagtt acgcagagca
    19981 gtccatccac gccggctttt tccgcttctt ccgaaaggtg gattgcctct ctggtacagt
    20041 ttgaaccggt tcctgcaacg accggaatac ggtgttttgc aaatttaaca gcagctttga
    20101 tcacctctgc atgctcttct gtcgtcagcg tagagctctc acctgttgta cctgcgataa
    20161 tgatacagtc cgttccctga ttgatctgat actcgatcat ctgctctaat ctgtcataat
    20221 ttacttcctc attgtttttc attggtgtta cgattgccac accggctcct ttaaaaatag
    20281 acatattaat aatcctcctg gttcctgtat tatgatacgt taggatacac tgctttgtgc
    20341 acacggtatt ttatttattc ataggacgta atttccctat gaattaaaaa aaccgactct
    20401 gatgagccgg ttcgtaaatt ctaatcatat gtattaccca gtatatgtcg aatccgatag
    20461 cgccccatct ttctgccatt tcagcttaag atgacagtca taaggttctt taccttatgc
    20521 ccaggaacat atccgcagca aatatactcc ttcggcgttc tttcctttta tcctccatcc
    20581 tctgcttctg ccacatccgg aaaactactc ttaaagcacg caacctctat caagcaatat
    20641 gtatctttta gcaatcatag caccatctat ttctactgtc aatccaattc ctctaaaaaa
    20701 tcaattttgc tgacggatac ttcgtatgca accctttttt ccgtctgcgt ctccgataat
    20761 tttttgacat attcgcggct ctggatcctg ccccagatct gcacatgtcc gcccacatca
    20821 aaaccggagg caaatcttgc atttcgtccc cagcagatgc acggaatgta atctgatttt
    20881 ccataagagc ggttcacagc gatcagaaga tctgcgatct ctcttccaag cggtgttttc
    20941 cggtaaattg gctccttaca tacatagccg tctaaaaaga tctggttgct ctttacctca
    21001 tcgtcaatct cgtctaaaaa ttccagttct ctcacaaaaa cggaaagtac aagccggttt
    21061 ttcttttcct cgtgccggtt gaatgagcgg aactgtcctg tcacataaat attctgtccg
    21121 accatgtcct cattgacatc gatcaatcgt tccgaaatca tcaatggtat gtaatccata
    21181 taattgctga gacggttgac tgccacatcg accatataaa atccctctcc gtacacttcg
    21241 tggctgaacc ggaaatccga tacaatctcc cccacgatcg acacctggtt gttttcaaac
    21301 attttatctg ccatgaatat tctcccttcc ttgcggtcat acacctatat ttttttgtgc
    21361 gttttttctt ttcgaaccgt ttctgcccgg tatgacctgc ctgacataat atttttacca
    21421 tgtatcacat tcaaattttc atggaacatg tcgataagaa aacgaatgta atgacaactt
    21481 ttgtcaggtt tttgaataaa aaaatattgc agaatcccac aaatatgata aaatatatag
    21541 gttggttttt taaccttatg ttacagttaa tacatttcac acaggaaaga gagattttgt
    21601 atatgaaaat gaaacgtgaa gatgtccgta atattgccat tattgcacac gttgaccacg
    21661 gtaaaacaac tctggtcgat gagctgctaa agcagagcgg cgtattccgc gcgaatcagg
    21721 aagttcagga acgtgtcatg gactccaatg atatcgagag agaacgtggt atcacgatcc
    21781 tttcaaaaaa cacagccatt acctataaag gtacaaagat caatgtcatc gatactcctg
    21841 gtcatgcgga ctttggtggt gaggttgagc gtgtccttaa aatggtaaac ggtgttatcc
    21901 ttgtcgttga cgcattcgag ggtgttatgc ctcagaccaa attcgtactg atgaaagcat
    21961 tagaactttc tcttccggtt atcgtatgtt taaataaagt agaccgtccg gaagcccgcc
    22021 cgaacgaggt tgtcgatgaa gtacttgagt tattcatgga cttagacgca tccgatgagc
    22081 agttagactg tccgttcctg tttgcatctg caagagacgg ctatgccgtt cgcgagatcg
    22141 gagatcttgt aaataacaaa aaagatatga cacctctgtt tgagactatc attgattaca
    22201 ttccggctcc agaaggtgat ccggatgcaa acacacaggt actcatcagt accatcgatt
    22261 acaacgagta tgtcggacgt atcggtatcg gtaaagtcga caacggatgc ttaaaagtaa
    22321 atcaggaagc tgttgtggta aaccatcatg aaccggacaa acagaaaaaa gtccgcatca
    22381 gcaaattata tgaatttgac ggcttaaata aagtagatgt cgcagaagca aagatcggat
    22441 cgatcgtagc aatctccggt atcgcagata tccacatcgg agatacgatc tgtgcaccgg
    22501 aaaatccggt tgcaataccg ttccagaaga tttctgagcc tacgctttcc atgaacttca
    22561 tggtaaacga cagcccgctc gccggacagg aaggtaaatt catcacttcc cgccatttaa
    22621 gagaccgtct gttcaaagaa ttaaataccg atgtttctct gcgtgtagaa gagacagaga
    22681 gtccggactg ctacaaagta tccggccgtg gtgagcttca cttatccgtt ttagttgaga
    22741 acatgcgccg tgaaggttat gagtttgcag tcagcaaagc agaagtttta taccacacag
    22801 acgagaacgg caaaaagaca gagcctatgg agatcgctta cgtcgatgtc ccggatgagt
    22861 ttaccggtac tgttatcgat aaattaagcc agcgtaaagg tgagcttgtc aatatgaaac
    22921 cgatcaccgg cggttacacc cgtctggagt ttaatattcc atcccgtggt ctcatcggtt
    22981 accgtggaga tttcatgaca gacaccaaag gaaacggtat catcaatacc attttcaacg
    23041 gctatgctcc ttaccgtggt gagatcgcat accgtaaact tggttccctg atcgcatttg
    23101 aatccggcga atccgtaact tatggtctgt tctctgccca ggaccgcggt actttattta
    23161 tcggacctgg cgaaaaagtt tatgccggaa tggtcatcgg ttcctgtgca agagctgagg
    23221 atatcgagtt aaacgtatgt aagaaaaaac atcttaccaa tacacgttct tcttctgctg
    23281 atgaagcact gacactggtt ccgccaaaag ttttaagttt agagcaggcg cttgacttca
    23341 tcgatgtcga tgagcttctt gaggtaacac cggagagcct tcgtatccgt aagcgtatct
    23401 tagatccaac cttacgcaaa cgtgctaata tgaaaaaata at
//
