LOCUS       NZ_CP124548.1          23560 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP124548.1 Actinomyces israelii strain F0345 chromosome, complete
            genome.
ACCESSION   NZ_CP124548
VERSION     NZ_CP124548.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:29:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2930228
            Orig. end    :: 2953788
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23560
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2940228:2943788]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13560
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..23560
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23560
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="7"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(754..1425)
                     /locus_tag="ctg1_2421"
                     /transl_table=11
                     /translation="MTATSMARDTRIIIVDDDPIVRSSLSSVISAEPGIELLATAANGA
                     EAVDLVHERTVDVVLMDVQMPVLDGVAATSRVLAASPTSRVLLLTTFDEDTFLDGGLAA
                     GASGFLLKTTPPTEIAAAIRTVHSGGKVLSPGPTSRILDRYVHGQSPTVDAANDLDLSG
                     REREVLAFLCQARSNQQIAHRLGVAETTVKSHVSSIMRKMGVSSRLEVVVEAHRRGLAG
                     R"
     CDS             complement(1422..2600)
                     /locus_tag="ctg1_2422"
                     /transl_table=11
                     /translation="MPVVIPVSCAARTRRDWWRVLLCAPDASAVQRVLRWAMAGLILAA
                     ACADLAVNGADLPTAASAVSCVSVLLVDRFPWTVTGLLSLGVLQFLAAGYITATLLTAL
                     LVFPLLVVEGRSQQSVLLAMCFPAGELIAVMRGHVVEDAQAFSFILLGAGLSSGLALRR
                     SRERVRRAEAAGAEALRAQRALIARELHDTLARTNTQIVLWARQARALGPPDERVAQAL
                     DEIIAAGCSSVRDLRAMLRVLRQEGREVPDLVPLSSLSAAEAFAGARRALEGAGLRASV
                     TCDGDLDDLPSVVATTLVRCLEESVANMVKYAAADAQCTIRIEVADGEVGLLVVNPVAD
                     GRRPDDAVVSSGYGLLGMQERASLLGGRLTHTDTGHQWVLALTLPLNPGDTP"
     CDS             2918..3661
                     /locus_tag="ctg1_2423"
                     /transl_table=11
                     /translation="MSSFKALTASLARVSLRDPATLLFFLIFPPTLLVVLANAASCCPG
                     ADGHGIVNSIGPNVMGFGVALIGMFAGMTNMAGWREKDAIRILRCAPMSVPAIRASALT
                     VALLFSVILSVIIMMVGVVPAVGMSLTPWAPLVMVPVFLGTLVFYSLGVLVGAAAPTAP
                     AGFPVMVGVTTTMSIASGAVVPLETLPQWVQALSDFTPMTYLLEGLRWPLTGVNGPDEA
                     LTGWAVTAAVGPVFFWATSGLMRWR"
     misc_feature    3368..3370
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(3734..7477)
                     /locus_tag="ctg1_2424"
                     /transl_table=11
                     /translation="MSKQAVPEADTRDARERRSREGQAAIRRLGAPVRARLRAGQVLVL
                     VSAVLAVAPYVALVRLGGVLLDAYNAGAAPDGQRVRGVVIMLVSAYSTRLFLYFVALLI
                     THVADLALRDRLRRDIVARISRAPLSWFTESTSGRIRKAVQDDTTTVHTVIAHGPVEQL
                     NAVVTPLALLACAFWIDWRLALLTLVPVVLYVLTYSVSMRGMKEKTVEMDRKLAAVSST
                     MVEFVSGIGVVKAFGRVGRAHAAYLNASDEFSAFYRAWAMPLVTITCLSFSWVSIPVLL
                     LVNLGGGALLMGAGVVTLPQVLATTLIALVLPGALITIASISWSYQLAGAAALRLCEVL
                     DTPVLPATDQPRRPEGARVAIDRVSFSYGDTLAVDDVSLTLEPGTVTALLGPSGSGKST
                     LATLIARFADPDSGTVRIGGVDLRDMDEETLYSTVSFVLQDAQLLGATVRENIALGRPD
                     ADLDQVRAAARVARIDEEIMALPAGYDTVLGRDTALSGGQEQRIAIARAVLLDTPVLLL
                     DEATAMADPESEAEIQEALSALVRDRTVLVIAHRPAAVRGAHRIVVMEAGRVVAVGAHS
                     DLLEEPHYRALLRQSGELAEEAPGSAASGGAPGAAKARSAADSAGAAETAETAETAETA
                     EAAGGPGSAQNDTGEPPAPRPAPGPQAPREAPRSLLARFHRLMAEASWRQTRICIILAV
                     VNGAVSGLALLALLPACVALATGEPCWGLSFRGWLVALAVCVIGAGVTEFQGQRRGMSG
                     ALGFMHDVHHAIGDRIVRLPLRWFTSETAGTLSRAVSQEMVALGESAAHFMYTLASTIA
                     ACAVIGVGSWAWDWRLGLLLTLAAPLFAGLIRGSRRLLNHGKSISEPAERELAVRVVEV
                     ARCQGALRACRATASYSRLRAAFDDGARASRRALWWETGGNIVNGALTQAVVIAMIVLT
                     AALAVGGSMGPLPAVATIGMCLRFTTMLDNVGASVMAMEERRQMMNHLDAVMDAELMAE
                     PEARSEPAEPGAVELDDVVFGYRTGERVLDGVSLSVPAHGMCAIVGPSGSGKTTIARLV
                     ARFWDADSGSVRVGGTDVRDMPTAQLMEQLSMVFQDVYLFDDTLAANIRVGDPRAADEQ
                     VRRAADLAGVTEIIDRLPHGWDTRVGEGGRALSGGERQRVSIARALLKRAPIVLLDEAT
                     SALDAENEANIVAAMEELRRTSTLIVIAHKLETIAAADQVIVLDDGGHVVQRGRHEELV
                     GAPGPYRDFWEQRTRARGWVLV"
     CDS             7598..8374
                     /locus_tag="ctg1_2425"
                     /transl_table=11
                     /translation="MTRLGKPTGPKPGFSRADVVEAALALGVADFTLTAVAGRLGVAVS
                     GLYRTIASREDLLAACLEQIAAQADFAHQGTTWQDEVRASAESMWELLEQHPGLAGVLI
                     GVPWAHQLFAGPFAEAHQTLVDRGLDPEDAGIVLDFVGDTVITMHAQIEVMRSPADQTV
                     FPSPPGAADGADGKASETLEDRKTRPTGLEEASRFAAASGRSRAIPAVLTPNESWIERG
                     GLDRKIEIIIRGVEASVPGLEEPSSARGSRRVLSSG"
     CDS             complement(8361..9872)
                     /locus_tag="ctg1_2426"
                     /transl_table=11
                     /translation="MSTRGADGGSARPFRRGPRHRARHKRRAARSRWRRPVLLASGLVI
                     IALAAVGAWVAQVHAQRDTVLGGVTVAGHEVGGMSRDQVVDLLSDKALAVTLTVVSEGH
                     TTSVSLAEAGGVIDAAATADAAMAGSGTWRGSALSLVRGRSVPVRTAVDRDAVEELGRR
                     IDSQTGGAPVDASMRLTEDGSAFEAVAGAPGRGVDRGALTGALEAAATSLSDQAIDLPA
                     EDMDPAVSLADAEAAAEAANRLIAPQVALSADKTTASAEVSVRASWVKSSAAAGRLEPG
                     LSRERVAEWVDGVAASAERAPINGIDNVDDAGTVLEPARPPKPGRIVTDRDAATSAIVE
                     ALEAGTAYSGSLTVEEDPASTEQRVVPAGPERFAYQAAPGEKWVDVNLTDSTLTAYEGT
                     TQVHGPILINHGGVGHETITGTYRVYLKREKQDMGCTPEWPYCEKDVPWIAYWHKDYAL
                     HGAPWAGEFGIGTDESSHGCVNIPVEDAHWIYDWIDVGTTVVTHY"
     CDS             complement(10001..10774)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2427"
                     /sec_met_domain="Fer4 (E-value: 4.8e-06, bitscore: 23.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.3e-06, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 9e-24, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.7e-11, bitscore: 41.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2e-05, bitscore: 22.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNIKLKIWRQQNQSSEGHFEEYPMSGIEEHMSFLEVLDLLNEQLF
                     AEGREPVAFDSDCREGICGQCGVVINGQAHGPIRSTTCQLHMRHLAEDPSFKDGDTITI
                     EPWRSAGFPILKDLIVDRSALDRIVQAGGYISVNTGAAPEAHSVPVRKEKADAAFEAAA
                     CIGCGACVAACPNASAMLFTGAKISHLGLLPQGQPERLARVVSMLGQHDAEGFGGCTNI
                     GECAAVCPKSVPLEVITRLNRDLGHALWKGQKAHA"
     CDS             complement(10771..12771)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2428"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-58, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-33,
                     bitscore: 112.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELIEGLYIEGDKIADTKAPHSVPIDKRWEQRKFEAQLVNPANR
                     RKLDIIVVGSGLAGGAAAASLGEQGYNVKCFFYQDSARRAHSIAAQGGINAAKNYRNDG
                     DSTYRLFYDTVKGGDYRAREDNVYRLAEVSANIIDQCVAQGVPFAREYGGLLDNRSFGG
                     VQVSRTFYARGQTGQQLLIGAYQALERQVHAGTVKEYRRHEMVELIVIDGRARGIVTRD
                     MVTGEIETFTADAVVLATGGYGNVFFLSTNAMGCNATAIWRAHRKGAYFANPCYTQIHP
                     TCIPQSGDFQSKLTLMSESLRNDGRIWVPKRAEDCDKDPREIPEEDRDYYLERIYPAFG
                     NLVPRDIASRQAKNMCDEGRGVGPAIKERDASGNERMMRRGVYLDFSEAIGRLGRDAVS
                     ARYGNLFEMYQRITGDDPYEVPMRIYPAVHYTMGGLWVDYDLESNIPGLYVGGEANFSD
                     HGANRLGASALMQGLADGYFVLPDTMNDYLADMLRLGKVDPNAPEIAEARRSVEERIAR
                     LMALRGTRSVDDFHMALGRIMWEYCGMERRDAGLREAIGQIRALKEEFWRDARITGRAD
                     ELNQALEKAGRLLDFFELAELMCIDALHRRESCGGHFRAESQTPEGEALRHDDEFLYVG
                     AWEWGGEGRPPILHKEDLIYKDIELKQRSYK"
     CDS             complement(12784..13560)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2429"
                     /sec_met_domain="SucD_FumR (E-value: 5.4e-10, bitscore:
                     36.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVKTSVPSKRTAYTTTVFMKRLMAWSGLFFLVFVLFHAYGNTHYF
                     EGEIAYDHYAYFLRRLLVPILPPSGVLWILRAALVACLLVHAGSAFHLWARNKRARGTD
                     RYAVKKPGAEYFASRYAMRTMRWGGVILLLFIIWHILQFTTLTITPGGRYEHGRAYMNM
                     WYGFQLWWVYLIYLVALAALCLHVWHGVWSALQTLGATRGNTVPFVRLIAFVVAFGLFV
                     AFMCVPTAILFGWVPEPMSAAEYTIKAAEAGIVLSH"
     CDS             complement(13741..14382)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2430"
                     /sec_met_domain="Acetyltransf_1 (E-value: 5.1e-16,
                     bitscore: 56.6, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRHDLGAVARAEALLFGAEAWSPALLHAELAAASGPAADRCYVV
                     VERVGGGARTAPGGADGAGGGELLGYAGLWFGDGDGDADLLTVATLPAARRRGVATAMI
                     AHLLRRARRAGCTAVLLEVRASNAGAQALYRRLGFAPIGRRRRYYLAPVEDALVMRADT
                     GVRHGAGADSASSAGRAGAVGAVGAEAAADSGAAGRADRAVVGRPPHLSD"
     CDS             complement(14490..15194)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2431"
                     /sec_met_domain="Peptidase_M22 (E-value: 2.2e-20, bitscore:
                     71.0, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIVSIDSSFGSRLLVADADLGSRVTLKTLSCAEQPDSRRHAESL
                     GVMLAEALRDPGVADRGLDAVVAATGPAPFTGLRAGLVTARALGRARGIPVHGVPSLDA
                     VARAALDRFADGSAAVLVVTDARRREVYAARYRARGADDVERMDEPAVLAPDAAADLDG
                     VDAVAGSGAALYPQIAAGRPVLAPVSGDARAQCRIALARLAAAGPGAVLPAEPLYLRHA
                     DVQPPTAPKRVR"
     CDS             complement(15272..16213)
                     /locus_tag="ctg1_2432"
                     /transl_table=11
                     /translation="MRGPFVRALPGLGALLLLAALLAGPQALAQTSPPSPEPAAPGMTA
                     PQVQEWINRRGQDMIHQEVARDASAGSPVNVETWSDGVLDATDLEDPTDPTNTWAAVIS
                     TAEGPVGVLVVEADGSEPSAMVQRDPELAAALTALPERAIVLREPAPPSAAAAASPTPS
                     PRPSPGTTTDSAEDPAATAQDDADGGGADDGVDTYADIADPAASDAWYALTDDVVTALD
                     EQAATGLAGPVGLSAYAQVLHDRAHGIVDTDKTDTRKGSHTLDLAIVYTGVGVLAIGAV
                     IVTTTFVHERRVMAPLRESPDSRAAEDADRAP"
     CDS             complement(16210..16782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TsaE"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2433"
                     /sec_met_domain="TsaE (E-value: 1.7e-31, bitscore: 106.4,
                     seeds: 801, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRAPHERGREVVIETADADATRDLGARLAALLRAGDLVVLSGA
                     LGAGKTTLAQGVGAAMGVRGRVSSPTFTIARVHPAPAGGPDLIHVDAYRLGSLEEVDAL
                     DLDSSMDESVTLVEWGRGKVEALSENRLEITVDRPRGGLSGDGAPAARPGSTAVADLAE
                     ADDSRRTVTVAATGPRWADVDLSRLKA"
     CDS             complement(16779..18191)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2434"
                     /sec_met_domain="Ala_racemase_N (E-value: 1.5e-52,
                     bitscore: 176.0, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLVTRSAPAPPAAPAELAGPAGPAATSRAVIDLDALAHNARVLA
                     DVAGVPWMAVVKADAYGHGLGPVALTCLRAGATWLGVAQLAEALHLRGLLDASGVARPL
                     PGRDPDPGHPRLLCWLAPVLSPERAAVPGSPLRAALEADLDLSASTTGQLAAVAAAGAA
                     GRAARPGATPARIHLKVDTGMSRAGAVASGLPALADAARGAQEAGDVEVVGLWSHLSRA
                     DEPASGSTEEHLSRFRAAEQVVREAGLSPRVRHLAATGGLLWHPAARLDLVRAGIGLYG
                     LSPDPGVATVDELGLRPVMRLEAPLTQVKRVPAGRAVSYGGTWTAPTDRWLGLVPLGYA
                     DGLPRTASSAGPVAVNGVRTSVVGRVCMDQVVIDLGPDDGGGAPAAAGDLAVLWGDPTA
                     AGADPATPTAQDWAQACGTIGYEIVTRLGARVPRVARGGGLDGSGDAGPVRGALSAPVA
                     AVEGGAEHQEGR"
     CDS             complement(18179..19855)
                     /locus_tag="ctg1_2435"
                     /transl_table=11
                     /translation="VSTVSTAPPTSPTLSPATAYRAEAVARAERGLTASTDRYMHLAAR
                     ALALAAARELRGAAGRATGRDVLLLVGGGHNGGDALLAGALLARRGCAVTAALATDHPH
                     AGALREAERAGVRPAPEPAAACERAAAGGTALVIDGLTGIGATGPLRARAAALVAPLAA
                     AGRRGARPFRVMAVDLPSGAGVDDGTVAGPVLAADLSVTFTCLKGAHILPPAAGACGRV
                     EVADLGLPVPADPGAVVASRPADADLGRLLRVPGDADHKYTRGVVGLWAGSRTYPGAAV
                     LTASAAARCGAGMVRLSAPHRVEDLVLARRPEVVPAPGRCQALVIGPGTDPADVVRGAE
                     LDAVVVRALDDDGGPDPAAPADPARGPLPAVFDAGALLLLAERLRGGMRCAPAHVLTPH
                     AGEAAALLTTLGGPTSRARVEAAPAACALELARLTGGTVLLKGAPTLIAAPDAPSAPAG
                     SARPRLLSVDAGPGWLATAGSGDALAGVLGTVLAAAQCDAERGGPAVDVPQCAALAVRL
                     HAVAAELASGLRDAPPGRPLAALDLADHLPHACAAVGGWAS"
     CDS             19930..20457
                     /locus_tag="ctg1_2436"
                     /transl_table=11
                     /translation="VACGAEPDRPRRGFRPVSAREGTLAGVILGIGTDLVAVGRLEARL
                     VSVPALAGRLFTPQERAACAGRATCLAGRFAAKEAVVKALGSALAEAGRGAPSGWRYTD
                     VEVVSAPGAPPRLALHGVARATAAGLGVAGWRLSLTHDDGRALAFVIAEGGGEGPDAPG
                     SRAAPGAPVTPR"
     CDS             complement(20444..22339)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2437"
                     /sec_met_domain="SIS (E-value: 2.4e-31, bitscore: 105.9,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGHVGPPTPSERSLAVLMDGLGRLEYRGYDSAGVALVGPGG
                     LDVVKAAGKLDNLRGALAAAPPPPAVCGIGHTRWATHGGPTTVNAHPHRAGSVAVVHNG
                     IIENFRSLRAEVEAAGRELLSATDTEVVAHLLDLDLAARLDAAGEALEEAGVAALLVES
                     MRAVTSRLEGAFALLAVTSLAPGAIVAARRSSPLVIGLGEGENFLGSDVAAFVAFTRRA
                     AEVDDDQVLLLTADEVRVWDADGTAVEPAAWEVSWDASAAVKGGYETFMDKEIHDQPTA
                     VADTLRGRVNEAGDLILDEMRIEASVLRSVDKIIVVACGTAAYAGHVAKYAIEHWCRIP
                     VEIELAHEFRYRDPIVSEKTLTVAISQSGETMDTIQAVRHAREQGSRVLAIVNTYGSTI
                     AREADAVLYTHAGPEVAVASTKAFLAQITACYLLGLYLAQLRGNKWHDEVADYLAQLER
                     MPARIQRLLNEQEEDVQELGAMLADRASFLFLGRHVGFPVALEGALKLKELAYVHAEGF
                     AAGELKHGPIALVEDGLPVFVIVPTPRRPVLHDKVISNIQEVRARGARTIVIAEEGDEA
                     VTPFADHVIRVPATPTLMWPLLTVVPLQIFAAALAKAKGLDVDQPRNLAKSVTVE"
     CDS             22454..23449
                     /locus_tag="ctg1_2438"
                     /transl_table=11
                     /translation="MRQTWAVSSAPSPYIEFSRNQWRALASTTPLPLTQADVEKLRGLG
                     DPIDLAEVDVVYRPLTALLEDYIATSRERARRISDFLGVGPHPTPFVIAVAGSVAVGKS
                     TTARLIAHLLARFPQTPQVTLVTTDGFLLPNAVLEERGLSARKGFPESYDRRALLDFVA
                     AVKSGAERVEAPVYSHTVYDIVPGGSVVVERPDVLVLEGLNVLQPAPRPRRVDRGSGPA
                     EREADAPALAVSDFIDFSIYVDADPEDIRRWYLDRFLTLKRTAFREPGSYFQRYATIRD
                     DIAVAAANEVWESINLVNLRENIAPTRGRATLVLHKDSQHHMHRVLLRKI"
ORIGIN
        1 gcatcgcacg cagatcccgc acggacgagc accccgccgc aatgatctca tcaagagcct
       61 gcgcgacccg ctcgtcgggc ggcccgaggg cccgagcctg ccgagcccat agaacgatct
      121 gggtattggt acgggcaagg gtgtcgtgaa gctcgcgagc gataagagcg cgctgagcgc
      181 gcagagcctc agcaccagcc gcctcagcgc gcctcacccg ctcacgggac cgccgcagcg
      241 ccagccccca gctcacgaag gcgccgagca ggagcatggt ggcaagggcc ttggcaatat
      301 ccggatggcc ggcgagagcc tccaggagaa gctcgagagg aaaggaaagc cccaggaccc
      361 aggcctgatg agaacgggca gcggagacca gcagggccag ggccatgatc ccggccagac
      421 tgatcacggt gaacttcccc caggggaacg ctgagataac tccgactgtc aatgcggagg
      481 tgaccgccca gggaaagcgg tcaatgagca ggatgaagat ccccgacagc agagcggcag
      541 aagcgactct gacgctggga ccgaatagat acaattccag cagggcgatc gcctcgagtg
      601 cgacgactac cgcccagcgg agcacacgcc tgcctctcaa ggtgcgcaaa ctgaagtacc
      661 gggaactgtg acggaagaac tgcgcgatcc gtggaacaaa gatagccggg agcactggga
      721 ggactctaat tcgggagact acggcaagat gcatcagcgc ccggccaggc cgcgacggtg
      781 ggcctcgacg acgacctcca ggcgactgga aacccccatc ttgcgcataa ttgatgagac
      841 atgagacttc acggtcgtct ctgcgacgcc gaggcggtga gcgatctgct gattggaacg
      901 cgcctggcac aggaaggcga gaacctcccg ctcgcgcccg gacaggtcca agtcgttcgc
      961 ggcgtctacg gtggggctct gtccgtgcac atagcggtcc aagatgcgac tggtcggccc
     1021 aggcgacaga accttgccgc cggagtgaac ggtgcggatc gccgcggcga tctcggtcgg
     1081 cggagtcgtt ttgaggagga atccggaggc accggcagcc aggccaccat cgagaaaggt
     1141 gtcctcgtcg aaggtcgtca gcagtagcac tcgtgaggtc gggctcgcag ccaagactcg
     1201 ggaagtcgcg gcgacaccgt cgaggacagg catctggaca tccatgagga ccacatcaac
     1261 cgtccgctca tggaccaggt ccaccgcctc ggctccgttg gccgccgtcg cgaggagctc
     1321 aatgcccggc tcggcgctga tcacgctgct gagggaactt ctcacaatgg ggtcgtcgtc
     1381 aacgatgata atacgagtgt cacgggccat ggaggtggcg gtcatggtgt gtctccgggg
     1441 ttgaggggca gggtcagggc gaggacccac tggtggcccg tatcagtatg cgtcagacgc
     1501 ccgcccagca aagaggcccg ctcctgcatg cccagcagac cgtaaccgga ggacacgacg
     1561 gcatcgtcgg gccgacgccc atcagcaacc ggattgacca cgagcagacc gacctcgccg
     1621 tcagcgacct caatacgaat agtgcactgc gcatcggcgg cggcgtactt gaccatattg
     1681 gccaccgact cctccagaca acgaacaaga gtcgtggcga ccaccgacgg cagatcgtca
     1741 agatcaccat cgcacgtcac cgaggccctc agcccggccc cctccagcgc acgacgagca
     1801 ccagcaaaag cctcagccgc gctcaaggag gacaacggca caagatccgg cacctcacga
     1861 ccctcctgac gcagcacacg cagcatcgca cgcagatccc gcacggacga gcaccccgcc
     1921 gcaatgatct catcaagagc ctgcgcgacc cgctcgtcgg gcggcccgag ggcccgagcc
     1981 tgccgagccc atagaacgat ctgggtattg gtacgggcaa gggtgtcgtg aagctcgcga
     2041 gcgataagag cgcgctgagc gcgcagagcc tcagcaccag ccgcctcagc gcgcctcacc
     2101 cgctcacggg accgccgcag cgccagaccc gagctcaagc ccgccccgag cagaataaaa
     2161 ctgaaggcct gggcgtcctc gacgacgtga ccgcgcatga ccgcaatgag ctctccggcg
     2221 gggaagcaca ttgcgagcag caccgactgc tggctgcgcc cctcgacgac gaggagcgga
     2281 aaaacgagga gagcggtaag caaagtcgca gtaatatagc cggcggccaa gaactgcaga
     2341 acccccagcg agagcaaccc ggtgaccgtc caggggaagc ggtcgacgag cagcacagac
     2401 acacacgaca ccgcggaggc cgcggtggga aggtctgcgc cgttaacggc caggtcagcg
     2461 caggcagcgg ccaagatcag acccgccatc gcccagcgga gcacccgctg gaccgccgag
     2521 gcgtctggcg cgcagaggag gacgcgccac cagtcgcgtc gggtccgcgc agcacacgac
     2581 acagggatca ccactggcat gaggcaagcc tatgcccacg atcactacag gtccatgggc
     2641 tcacctgggc tgggggacgg gcgaagcgca caatcaccgt cctctcctac caaaacagga
     2701 gcagcgaccg gcaaaaggca ggatccgcca acgcgatgct cgaacagatg cttgccgtat
     2761 cagcagcgag ccgcggctcg ccgagccgcc ccgggcagcg gtccgcggga tcgatcgaac
     2821 cacgccgcag cccggcgctc gggtgccgag cctcgatcag gcccccgcgt ccacggcccc
     2881 gtcctcgacc acatcgaact cgctggaaag gaacacgatg agctccttca aggcgctgac
     2941 cgcgtctctg gcgcgcgtct ccttgcgcga tcccgccaca ctgctcttct tcctcatctt
     3001 ccccccgacc cttctcgtcg tgctggcgaa cgcggcgagc tgctgtccgg gagccgatgg
     3061 acacgggatc gttaactcca tcggccccaa cgtgatgggc ttcggtgtcg ccctcatcgg
     3121 catgttcgcc gggatgacga acatggcggg gtggcgggag aaggatgcga tccggatcct
     3181 gcggtgcgcc ccgatgagcg tgccggccat ccgcgcctcc gcgctgacgg ttgcgctcct
     3241 cttctccgtc attctgtcgg tcatcatcat gatggtgggt gtcgttcccg ctgtggggat
     3301 gagtctgacc ccgtgggcgc cgctcgtcat ggtacccgtc ttcctgggga cccttgtctt
     3361 ctactcctta ggagttctag tcggagcagc cgcgccgact gcgccggcag gtttcccggt
     3421 catggtggga gtcaccacga ccatgagtat cgcctcaggg gcagtggtcc ccctcgagac
     3481 gctcccgcag tgggtgcagg cgctgagcga ctttactccg atgacctacc tgctggaggg
     3541 cctgcggtgg ccgctaaccg gcgtcaacgg ccccgatgag gcactgaccg gctgggccgt
     3601 gacggcggcg gtcggtcccg tcttcttctg ggccacttcc gggctcatgc gctggaggtg
     3661 aggaacggct cgtctctcgc acaaacccgc tcgcgcagac cggcccctgc atgcacgcgc
     3721 tccccaggcc gtctcacacg aggacccagc cgcgggcacg ggtccgctgc tcccagaagt
     3781 cccggtaggg gcccggcgcg cccacgagct cctcgtgccg gccgcgctgg acgacatgac
     3841 cgccgtcgtc gaggacgatc acctggtccg ccgcagcgat cgtctccagc ttgtgggcga
     3901 tgacgatgag cgtcgaggtg cgccgcagct cctccatggc ggccacgata ttggcctcgt
     3961 tctccgcgtc cagggcgctg gtggcctcgt cgagcaggac gatcggcgcg cgcttgagca
     4021 gggcccgggc gatggagacg cgctggcgct ccccgccgga cagggcgcgc ccgccctccc
     4081 ccacgcgggt gtcccacccg tgcggcaggc ggtcgatgat ctcggtgacg ccggcgaggt
     4141 cagcggcccg gcgcacctgc tcgtcggcgg ccctcgggtc cccgacgcgg atattggcgg
     4201 ccagggtgtc gtcgaagagg tagacgtcct ggaagaccat ggacagctgc tccatgagct
     4261 gggcggtcgg catgtcgcgc acgtcggtgc cgcccacgcg cacgctcccg gagtcggcgt
     4321 cccagaagcg ggcgaccagc cgggcgatcg tcgtcttgcc gctgccggag gggcccacga
     4381 tcgcgcacat gccgtgcgcg ggcacgctca gcgacacgcc gtccagcact ctctcacccg
     4441 tccggtagcc gaagacgacg tcgtcgagct cgacggcccc gggctcggcc ggctcggagc
     4501 gggcctccgg ctcggccatg agctcggcgt ccatgacggc gtcgagatgg ttcatcatct
     4561 gccggcgctc ctccatggcc atgacggagg cgccgacgtt gtcgagcatg gtggtgaagc
     4621 gcaggcacat gccgatggtg gcgaccgcgg ggagcggccc catggagccg ccgacggcga
     4681 gcgcggccgt caggacgatc atggcgatga caacggcctg ggtgagtgcg ccgttgacga
     4741 tattgccccc ggtctcccac cacagggcgc gcctggaggc gcgggccccg tcgtcgaagg
     4801 cggctctcag gcgcgagtag ctcgcggtgg ctcggcaggc gcgcagggcg ccctggcagc
     4861 gggcgacctc gaccacgcgg acggcgagct cgcgctcggc gggctcggag atcgacttgc
     4921 cgtggttcag taggcggcgc gagccgcgga tgagcccggc gaacagcggg gcggcgagcg
     4981 tgagcaggag gcccaggcgc cagtcccacg cccatgagcc gacgccgatg accgcgcagg
     5041 ccgcgatcgt ggaggcgagc gtgtacatga agtgggcggc ggactcgccc agggccacca
     5101 tctcctggct gacggcccgc gacagggtgc cggcggtctc ggaggtgaac cagcgcaggg
     5161 gcaggcgcac gatccggtcg ccgatcgcgt ggtggacgtc gtgcatgaag ccgagcgccc
     5221 cggacatgcc ccggcgctgc ccctggaact ccgtgacgcc ggcaccgatg acgcagacgg
     5281 ccagggccac gagccagccg cggaaggaca gaccccagca gggctcgccg gtggccaggg
     5341 cgacgcaggc gggcagcagc gccagcaggg cgaggcccga cactgcgccg ttgacgaccg
     5401 ccaggatgat gcagatcctc gtctgccgcc acgaggcctc ggccatgagc cggtggaagc
     5461 gggccagcag ggagcgcggg gcctcgcggg gggcctgggg cccgggtgcc ggacggggtg
     5521 ccgggggctc gccggtgtcg ttctgcgcgg agcccgggcc gccggcggcc tcagctgtct
     5581 cagcggtctc ggcggtctcg gcggtctcgg cggccccagc ggagtccgcg gcgctgcgcg
     5641 ccttggcggc accgggcgcg ccaccgctcg cggcggagcc cggggcctcc tcggccagct
     5701 cgccggactg gcgcagcagg gcgcggtagt ggggctcctc cagcaggtcg gagtgggcgc
     5761 cgacggcgac cacgcgcccg gcctccatga cgacgatgcg gtgggcgccg cgcaccgcgg
     5821 ccgggcggtg ggcgatgacc aggaccgtgc ggtcccgcac cagggcgctc agcgcctcct
     5881 ggatctcggc ctcggactcg gggtcggcca tggcggtggc ctcgtcgagg agaaggacgg
     5941 gggtgtccag caggacggcg cgggcgatgg cgatgcgctg ctcctggccg ccggacaggg
     6001 ccgtgtcccg gcccaggacg gtgtcgtagc cagcgggcag ggccatgatc tcctcgtcaa
     6061 tgcgggcgac ccgggcggcg gcgcgcacct ggtccaggtc ggcgtcgggc cgtccgagcg
     6121 cgatgttctc ccggaccgtg gcgccgagga gctgggcgtc ctggaggacg aaggagacgg
     6181 tggagtagag ggtctcctcg tccatgtcgc gcaggtccac cccgccgatg cgcacggtgc
     6241 cggagtcggg gtcggcgaag cgggcgatga gggtggccag cgtcgacttg cccgagccgg
     6301 aggggcccag gagcgccgtg acggtgccgg gctccagggt cagggagacg tcgtcgacgg
     6361 cgagggtgtc cccgtaggag aaggagacgc ggtcgatcgc cacgcgcgcc ccctcggggc
     6421 gccggggctg gtcggtggcg ggcaggacgg gggtgtcgag gacctcgcac aggcgcagcg
     6481 cggccgcgcc ggccagctgg taggaccagg agatcgacgc gatggtgatg agcgccccgg
     6541 gcaggaccag ggcgatgagg gtcgtggcca ggacctgggg cagggtgacg acccccgcgc
     6601 ccatcagcag cgccccgccg ccgaggttga ccaggagcag gacggggatc gagacccatg
     6661 agaaggacag gcaggtgatg gtcaccaggg gcatggccca ggctcggtag aaggcggaga
     6721 actcgtcgga ggcgttcagg taggcggcgt gggcgcgccc gacgcgcccg aaggccttga
     6781 ccacgccgat cccggagacg aactcgacca tggtggagga cacggcggcc agcttgcggt
     6841 ccatctcgac ggtcttctcc ttcatgccgc gcatggacac ggagtaggtc agcacgtaca
     6901 gcaccacggg caccagcgtc agcagggcca ggcgccagtc gatccagaag gcgcaggcga
     6961 gcagtgccag cggggtgacg acggcgttga gctgctcgac gggcccgtgg gcgatgacag
     7021 tgtggacggt ggtggtgtcg tcctggacgg ccttgcggat gcgcccggag gtggactcgg
     7081 tgaaccagga cagcggggcg cgggagatgc gcgcaacgat gtcgcggcgc agccggtccc
     7141 gcagggcgag gtcggccaca tgggtgatga gcagcgccac gaagtacagg aacaggcgcg
     7201 tggagtaggc gctcacgagc atgatgacga caccgcgcac ccgctgcccg tccggggcgg
     7261 cgccggcgtt gtaggcgtcc aggaggacac cgccgagccg gaccagcgcg acatagggcg
     7321 ccacggccag gaccgccgag accaggacga gaacctgccc cgcccgcagc cgggcgcgca
     7381 caggggcgcc gaggcgcctg atggcggcct gcccctcgcg agagcgcctc tcgcgggcgt
     7441 ccctggtgtc ggcctccggc accgcttgct tgctcatcga gtgcctcgat ccaatggtca
     7501 acctaatact gaagtacttt cagacctgac gaagggcgac cttactccca gcgccgtccc
     7561 gcgggcaacc gccgtcacca cccactacgg tgaccccatg acacgactgg ggaagcccac
     7621 cggaccgaag cccggattct cacgcgcgga cgtggtcgag gctgccctcg ccctcggggt
     7681 ggccgacttc accctgaccg cggtggccgg ccgcctgggg gtggcggtct ccgggctgta
     7741 ccgcacgatc gcctcgcgtg aggaccttct ggcggcctgc ctggagcaga tcgcggctca
     7801 ggccgacttc gcccaccagg gcaccacctg gcaggacgag gtacgcgcca gcgccgaaag
     7861 catgtgggag ctgctcgaac agcacccggg actggccggc gtcctcatag gcgtgccctg
     7921 ggcccaccag ctcttcgccg gccccttcgc cgaggcccac cagaccctgg tcgaccgcgg
     7981 cctggacccc gaggacgccg gcatcgtcct cgacttcgtg ggcgacaccg tcatcaccat
     8041 gcacgcgcag atcgaggtca tgcgctcccc cgccgaccag accgtattcc cgtctccacc
     8101 cggggcggcg gacggggcgg acggcaaggc ctccgagacc ctggaggatc ggaagacccg
     8161 cccgacggga ctggaggagg cgagccgttt cgccgccgcc tccggccgct cccgcgccat
     8221 acccgcagtg ctgaccccca atgagagctg gatcgaacgg ggcgggctgg accggaagat
     8281 cgagatcatt atccgcggcg ttgaggcctc cgtcccgggc ctggaggagc cgagcagcgc
     8341 ccgcggcagc cggcgagtgc tcagtagtgg gtgaccaccg tggtcccgac gtcgatccag
     8401 tcgtagatcc agtgcgcgtc ctccacgggg atgttgacgc agccgtgcga ggactcgtcg
     8461 gtgccgatgc cgaactcgcc ggcccacggc gcgccgtgca gggcgtagtc cttgtgccag
     8521 tatgcgatcc aggggacgtc cttctcgcag tagggccact cgggggtgca gcccatgtcc
     8581 tgcttctcgc gcttgaggta gacgcggtac gtgccggtga tggtctcgtg cccgacgccg
     8641 ccgtggttaa tgaggatcgg cccgtggacc tgcgtggtcc cctcataggc cgtcagggtg
     8701 gagtcggtca ggttcacatc gacccacttc tcgcccgggg ccgcctggta ggcgaagcgc
     8761 tcggggccgg ccggcaccac ccgctgctcc gtgctcgcgg ggtcctcctc gaccgtcagc
     8821 gagccggagt aggccgtccc cgcctccagc gcctccacaa tggcgctggt cgcggcatca
     8881 cggtcggtga cgatccttcc gggcttggga gggcgggccg gctccagaac ggtgccggcg
     8941 tcgtcgacat tgtcaatgcc gttgatcggc gcccgctcgg ccgaggcggc gaccccgtcg
     9001 acccactccg cgaccctctc ccgcgacagg cccggctcca gccgcccggc cgccgcggag
     9061 gacttcaccc aggaggcgcg cacggagacc tcggcgctcg ccgtcgtctt gtcggcgctc
     9121 agggcgacct gcggagcgat gagtctgttc gcggcctcgg cggcggcctc ggcgtccgcc
     9181 agggacaccg cggggtccat gtcctcggcg ggcaggtcga tcgcctggtc gctcaggctg
     9241 gtggcggccg cctccagggc gccggtgagc gcgccgcgat ccactccgcg ccccggagca
     9301 ccggcgaccg cctcgaaggc ggagccgtcc tccgtcaggc gcatggaggc gtcgaccggg
     9361 gcgccgccgg tctgggagtc gatgcggcgc cccagctctt cgacggcgtc ccggtcgacg
     9421 gcggttcgca ccgggaccga gcggcctctc accagcgaca gggcactgcc cctccaggtc
     9481 cccgagcccg ccatggcggc gtcggcggtc gcggctgcgt cgatgacccc tccggcctca
     9541 gccagggaga cgctggtcgt atggccctcg ctgacaacgg tgagcgtcac tgcgagtgcc
     9601 ttgtcgctca gaaggtcgac gacctggtct cggctcatcc ccccgacctc gtgcccggcc
     9661 acggtgacgc cgcccagcac cgtgtcgcgc tgggcgtgga cctgtgcgac ccacgccccc
     9721 acggccgcca gcgcaatgat caccagcccg gacgccagaa gcaccggccg gcgccatctg
     9781 ctccgcgccg ctcgcctctt gtgtcgggct ctgtgccggg gcccgcgccg gaacgggcgg
     9841 gcggacccgc catcagcgcc acgcgtactc atcagacctc cggcgcgtga ttgtatcgca
     9901 gcccgcgtcc ccggtcacgg ccgcccgggg cccctggcgc ggggccgccc ctcccggcgg
     9961 cggacccccc gcgccggtgg cgcgagccgg ggagaatcgc tcaggcgtgc gccttctgcc
    10021 ccttccacag ggcgtggccc aggtcgcggt tgagccgggt gatgacctcc agcggcaccg
    10081 acttggggca caccgcggcg cactcgccga tgttcgtgca gccgccgaag ccctcggcgt
    10141 cgtgctgtcc cagcatgctg accacgcggg cgaggcgctc tggctgaccc tgcggcagca
    10201 ggcccaggtg cgagatcttc gcgccggtga acagcatggc cgaggcgttc gggcaggccg
    10261 ccacgcaggc gccgcagccg atgcaggcgg cggcctcgaa ggcggcgtcg gccttctcct
    10321 tgcgcacggg caccgagtgg gcctcggggg ccgccccggt gttgaccgag atgtagccgc
    10381 cggcctggac gatgcggtcc agggcggagc ggtcgacgat gaggtccttg aggatcggga
    10441 agcccgccga gcgccagggc tcgatggtga tggtgtcgcc gtccttgaag gaggggtcct
    10501 cggccaggtg gcgcatgtgc agctggcagg tcgtcgagcg gatcgggccg tgggcctggc
    10561 cgttgatgac cacgccgcac tggccgcaga tgccctcgcg gcagtccgag tcgaaggcga
    10621 ccggctccct gccctcggcg aagagctgct cgttgagcag gtccaggacc tccaggaagc
    10681 tcatgtgctc ctcgatgccg gacatcgggt actcctcgaa gtgcccctcg gagctctggt
    10741 tctgctgccg ccagatctta agcttgatgt tcacttgtaa ctccgctgct tgagctcgat
    10801 gtccttgtag atgaggtcct ccttgtggag gatcggcggc cggccctcgc cgccccactc
    10861 ccacgcgccg acgtagagga actcgtcgtc gtggcgcagt gcctcgccct caggagtctg
    10921 ggactcagcc cggaagtggc cgccgcagga ctcgcggcgg tgcagggcgt cgatgcacat
    10981 gagctcggcc agctcgaaga agtcgagcag gcggcccgcc ttctccaggg cctggttgag
    11041 ctcgtcggcc ctgcccgtga tgcgggcgtc gcgccagaac tcctccttca gggcccggat
    11101 ctgcccgatg gcctcgcgca ggcctgcgtc ccggcgctcc atgccgcagt actcccacat
    11161 aatgcgcccc agcgccatgt ggaagtcgtc cacgctgcgg gtgccgcgca gggccatgag
    11221 ccgggcgatg cgctcctcga cgctccgcct ggcctcggcg atctccgggg cgttcgggtc
    11281 caccttgccc aggcgcagca tgtccgccag gtagtcgttc atggtgtccg gcaggacgaa
    11341 gtagccgtcg gccaggccct gcatgagggc ggaggcgccc aggcggttcg ccccgtggtc
    11401 ggagaagttg gcctcgccgc ccacgtacag cccggggatg ttggactcca ggtcgtagtc
    11461 gacccacagc ccgcccatcg tgtagtggac cgccgggtag atgcgcatcg gcacctcgta
    11521 ggggtcgtcg ccggtgatgc gctggtacat ctcgaacagg ttcccgtagc gggccgagac
    11581 ggcgtcccgg cccaggcgcc cgatggcctc ggagaagtcg aggtagacgc cgcggcgcat
    11641 catgcgctcg ttgccgctcg cgtcgcgctc cttgatggcc gggcccacgc cgcggccctc
    11701 gtcgcacatg ttcttcgcct ggcgcgaggc gatgtcgcgc gggaccaggt tgccgaaggc
    11761 ggggtagatc cgctccaggt agtagtcgcg gtcctcctcg gggatctcgc gcgggtcctt
    11821 gtcgcagtcc tcggcccgct tgggcaccca gatgcggccg tcgttgcgca gcgactcgct
    11881 catgagggtg agcttggact ggaagtcgcc ggactgcggg atgcaggtgg ggtggatctg
    11941 cgtgtagcag gggttggcga agtaggcgcc cttgcggtgc gcgcgccaga tggctgtggc
    12001 gttgcagccc atggcattgg tggacaggaa gaagacgttg ccgtagccgc cggtggccag
    12061 cacgacggcg tcggcggtga aggtctcgat ctcgccggtg accatgtcgc gggtgacgat
    12121 gccgcgggcc cggccgtcga tgacgatgag ctcgaccatc tcgtggcggc ggtactcctt
    12181 gacggtgccg gcgtgcacct ggcgctccag ggcctggtag gcgccgatga ggagctgctg
    12241 gccggtctgg ccgcgggcgt agaaggtgcg cgagacctgg acgccgccga aggagcggtt
    12301 gtccagcagg ccgccgtact cgcgggcgaa gggcacgccc tgggccacgc actggtcaat
    12361 gatgttggcg ctcacctcgg ccaggcggta gacgttgtcc tcgcgggcgc ggtagtcgcc
    12421 gcccttgacc gtgtcgtaga agagacggta ggtggagtcg ccgtcgttgc ggtagttctt
    12481 ggcggcgttg atgccgccct gggcggcgat ggagtgcgcg cggcgggcgg agtcctggta
    12541 gaagaagcac ttgacgttgt agccctgctc ccccagggaa gcggccgcgg cgccgccggc
    12601 caggccggag ccgacgacga taatgtcgag cttgcggcgg ttggcggggt tgaccagctg
    12661 ggcctcgaac ttgcgctgct cccagcgctt gtcgatgggg acggagtggg gcgccttggt
    12721 gtcggcgatc ttgtcgccct cgatgtacag gccctcgatg agttcagtca tggtcgttcg
    12781 ctctcagtgg gaaaggacga tgccggcctc ggcggccttg atcgtgtact cggcggcgct
    12841 catgggctcc ggcacccagc cgaagaggat cgccgtgggc acgcacatga aggcgacgaa
    12901 caggccgaag gcgacgacga aggcaatgag gcggacgaag gggacggtgt tgccgcgggt
    12961 ggcgcccagg gtctggaggg ccgaccacac gccgtgccac acgtgcaggc acagggccgc
    13021 gagcgcgacg aggtagatga ggtagaccca ccacagctgg aagccgtacc acatgttcat
    13081 ataggcgcgg ccgtgctcgt agcggccgcc gggggtgatc gtcagggtgg tgaactgcag
    13141 gatgtgccag atgatgaaca gcagcaggat gacgccgccc catcgcatgg tgcgcatggc
    13201 gtagcgcgag gcgaagtact cggcgccggg cttcttgacc gcgtacctgt cggtgccgcg
    13261 cgccctcttg ttgcgggccc acaggtggaa ggcgctgccg gcgtggacca ggaggcaggc
    13321 cacgagggcg gcgcgcagga tccacaggac gccggagggg ggcaggatcg gcacgagcag
    13381 ccggcgcagg aagtaggcgt agtggtcgta ggcgatctcg ccctcgaagt agtgggtgtt
    13441 gccgtaggcg tggaagagga cgaagacgag gaagaacagg cccgaccagg ccatcaggcg
    13501 tttcatgaag accgtcgtcg tgtaggcggt cctcttggag ggaacagacg ttttgaccac
    13561 gaggacaggt taacgaaagt ccgcgggcga cggacccgca tcctgcgggc ctcccggacc
    13621 ccttgatgac gaagcgcgcg atcgcgccga aagaaccggt tctcccgtgc tcgccgagag
    13681 gaagccgggt cacggttccg cagcgctgga gggccgtgga ctgacctatt tcgtgacgcg
    13741 ctagtcagac aaatgaggag ggcgcccgac gacggcgcgg tcggctcgtc cggcggcccc
    13801 ggagtcggcc gccgcctcgg cccccacggc ccccacagcg ccggcgcggc ccgcagagct
    13861 cgcggagtct gcgcccgcgc cgtgtcgcac accggtgtcc gcgcgcatga cgagcgcgtc
    13921 ctcgaccggt gcgaggtagt agcgccgccg tctgccgatg ggggcgaagc ccagacggcg
    13981 gtagagcgcc tgggcgcccg cgttcgaggc gcgcacctcc agcaggacgg cggtgcagcc
    14041 cgcccgtcgg gcgcgccgca ggaggtgggc gatcatggcg gtggcgacgc cccgcctgcg
    14101 cgcggcgggg agggtcgcca cggtcagcag gtcggcgtcg ccgtcgccgt cgccgaacca
    14161 gagcccggca tagcccagga gctccccgcc gccggcaccg tctgcaccgc ccggtgcggt
    14221 gcgcgcaccc ccaccgaccc gctcgacgac gacgtagcac cggtcggcgg ccggcccgga
    14281 ggcggccgcc agctcggcgt gcagcagcgc cgggctccag gcctccgcgc cgaacaggag
    14341 ggcctctgcg cgggcgacgg cccccaggtc gtgccgcccc atgggcctca ggagcgctcc
    14401 gtcgggcggg gcaccctccc ccgcccggcc tggctcccaa gaactccgct gcggcgggcc
    14461 cggcgggctc tgcgcagcca ccggacccgt caccggaccc gcttgggcgc ggtgggcggc
    14521 tgcacgtcgg cgtggcgcag gtacagcggc tcggcgggga gcaccgctcc cggtccggcg
    14581 gccgcgagcc gggccagggc gatgcggcac tgggcgcggg cgtcgccgga gacgggcgcg
    14641 agaacggggc gccccgccgc gatctgcggg tacagcgccg cgccggagcc ggccacggcg
    14701 tcgacgccgt ccagatcggc ggccgcgtcg ggggccagca ctgccggctc gtccatgcgt
    14761 tcgacgtcgt cggcgccccg ggcgcggtag cgggcggcat agacctcgcg gcggcgggcg
    14821 tcggtgacca cgaggacggc ggcgctcccg tccgcaaacc ggtcgagagc ggcccgcgcg
    14881 accgcgtcca ggctgggcac gccgtggacg gggatgccgc gggcgcgccc gagcgcgcgg
    14941 gcggtcacca ggccggcgcg cagcccggtg aagggcgccg gcccggtggc ggccacgacg
    15001 gcgtcgagcc cgcggtcggc gacccccgga tctctcagag cctcggcgag catgaccccc
    15061 agggactccg cgtggcgccg ggagtcgggc tgctcggcgc agctgagcgt cttcagggtc
    15121 acccggcttc cgaggtccgc gtccgcgacg aggagccggc tgccgaagga ggagtcgatg
    15181 gagacaatgc gcacggccac agcctaaatg attgactccg aggcgggcgg accgggcgac
    15241 ccgggcccca gtccgccggc tcacggggct ctcacggggc ccggtcggcg tcctcggcgg
    15301 ccctcgagtc ggggctctcg cgcagggggg ccatgacgcg ccgctcgtgc acgaaggtgg
    15361 tggtgacgat gaccgcgccg atggcgagga cgcccacgcc cgtgtagacg atggccaggt
    15421 ccagcgtgtg cgagcccttc cgggtatcgg tcttgtctgt gtcgacgatg ccgtgcgccc
    15481 ggtcgtggag gacctgggcg taggccgaca ggccgaccgg ccctgccagg ccggtcgcgg
    15541 cctgctcgtc cagcgcggtg acgacgtcgt cggtcagggc gtaccaggcg tcgctcgcgg
    15601 cggggtccgc gatgtccgcg taggtgtcaa caccgtcgtc ggcgccgccc ccgtcggcgt
    15661 catcctgcgc cgtggccgcc gggtcctccg cggagtccgt cgtcgtcccc ggcgagggcc
    15721 gcggtgaggg cgtgggcgac gccgccgcgg cggcggaggg aggagccggc tcccgcagga
    15781 cgatggcccg ctcgggcagc gccgtcaggg cggccgcgag ctcggggtcg cgctgcacca
    15841 tcgcggacgg ctcggagccg tcggcctcga cgacgagcac gccgaccggg ccctctgcgg
    15901 tggagatgac ggcggcccag gtgttcgtcg gatcggtggg gtcctccagg tcggtggcgt
    15961 cgagcacgcc gtccgaccag gtctcgacgt tgacggggct gcccgcggag gcgtcccggg
    16021 cgacctcctg gtggatcatg tcctgacccc ggcggttgat ccactcctgg acctgggggg
    16081 ccgtcatgcc cggcgcagcc ggctcggggg acggcgggga ggtctgggcg agcgcctggg
    16141 ggcccgccag gagcgcagcc agcagcagga gagcgcccag accgggaagc gcgcgcacga
    16201 atggccccct catgccttca gacggctcag atcgacgtcg gcccaccggg ggccggtcgc
    16261 ggcgacggtc acggtgcgcc gggagtcgtc cgcctcggcc aggtcggcga cggcggtgga
    16321 gccggggcgg gccgcggggg cgccgtcccc gctcaggccg ccgcggggcc ggtcaacggt
    16381 gatctccagg cggttctcag acagcgcctc gaccttgccg cgcccccact cgaccagggt
    16441 cacggactcg tccatggagg agtccaggtc gagggcgtcg acctcctcca gggagcccag
    16501 gcggtaggcg tccacgtgga tgaggtccgg gccgcccgcc ggcgccgggt ggacgcgggc
    16561 gatcgtgaag gtcggggacg acacgcgccc gcgcaccccc atggcggcgc ccacgccctg
    16621 ggcgagggtg gtcttgcccg cccccagcgc cccggagagc acgacgaggt cgccggccct
    16681 cagcagggcg gccaggcgag cccccaggtc cctggtggca tcggcgtcgg cggtctcgat
    16741 gaccacctcg cggccccgtt cgtgcggggc ccggccgctc atcgcccctc ctggtgctcg
    16801 gccccgccct cgaccgcggc gactggagcc gacagcgcgc cccggacggg tccggcgtcc
    16861 ccggagccgt ccagcccgcc gccgcgggcc acgcggggca cgcgggcgcc caggcgggtg
    16921 acgatctcgt agccaatggt gccgcacgcc tgcgcccagt cctgggcggt cggggtggcg
    16981 gggtcggcgc cggccgccgt cggatcgccc cacagcacgg cgaggtcgcc cgccgcggcc
    17041 ggcgccccgc cgccgtcgtc gggccccagg tcgatgacga cctggtccat gcacaccctg
    17101 ccgaccacgc tcgtgcgcac gccgttgacg gcgacggggc cggccgagga ggcggtgcgc
    17161 ggcaggccgt cggcgtagcc gagcgggacg aggcccagcc accggtcggt gggcgccgtc
    17221 cacgtgccgc cgtaggagac ggcccggccc gcgggcacgc gcttgacctg cgtcaggggc
    17281 gcctccagcc gcatgacggg gcgcagcccc agctcgtcca cggtggcgac gcccgggtcg
    17341 ggcgacagcc cgtacaggcc gatgcccgcg cgcaccaggt ccaggcgggc ggcggggtgc
    17401 cacaggagcc cgccggtggc cgccaggtga cgcacgcgcg ggctcagtcc ggcctcgcgc
    17461 acgacctgct cggcggcgcg gaagcgggac aggtgctcct cggtggagcc ggaggcgggc
    17521 tcgtcggcgc gcgagaggtg ggaccacagg ccgaccacct cgacgtcgcc cgcctcctgg
    17581 gccccgcgcg cggcgtcggc cagcgctggc agcccggagg cgacggcgcc ggcccgggac
    17641 atgccggtgt cgaccttgag atggatgcgg gcgggcgtcg caccggggcg ggcggcgcgg
    17701 cctgcggctc cggccgcggc caccgccgcg agctggccgg tggtggacgc cgacaggtcg
    17761 aggtccgcct ccagggcggc gcgaagcggg gagccgggga cggcggcccg ctcgggagag
    17821 agtaccgggg cgagccagca cagcaggcgc gggtgcccgg ggtcggggtc gcgtcccggg
    17881 agcgggcggg cgacgccgga ggcgtcgagc aggccgcgca ggtggagcgc ctcggcgagc
    17941 tgggcgacgc cgagccaggt ggcgcccgcc cgcaggcagg tcagggccac cggccccagg
    18001 ccgtgcccgt aggcgtcggc cttgaccacg gccatccagg gcacgccggc gacgtcggcc
    18061 aggacgcggg cgttgtgggc cagcgcgtcc aggtcgatga cggcccgcga cgtagcggcg
    18121 ggcccggcgg gtcctgcgag ctctgcgggg gcggcgggcg gggcgggtgc tgagcgggtc
    18181 acgaggccca tcctcccacc gcggcgcagg catggggcag gtggtcggcc aggtcgaggg
    18241 cggccagcgg gcggccgggc ggggcgtcgc gcaggcccga ggcgagctcg gcggccacgg
    18301 cgtggaggcg cacggccagc gcagcgcact gggggacgtc gacggcgggg ccgccgcgct
    18361 cggcgtcgca ctgcgcggcc gccagcacgg tgccgaggac ccccgccagc gcgtcgccgc
    18421 tgccggcggt ggccagccac ccgggcccgg cgtccacgga cagcaggcgc gggcgcgcgg
    18481 agccggcggg cgcggagggg gcgtcaggcg cagcgatgag cgtcggcgca cccttgagca
    18541 ggacggtgcc cccggtcagc cgggccagct cgagggcgca cgcggccggc gccgcctcga
    18601 cccgggcgcg gctggtcggc ccgcccagcg tcgtcaggag ggcggcggcc tcccccgcgt
    18661 gcggtgtcag gacgtgcgcg ggggcgcagc gcatcccgcc ccgcaggcgc tcggcgagca
    18721 gcaggagggc gccggcgtcg aagacggcgg gcaggggccc gcgggccggg tccgcgggcg
    18781 ccgccgggtc cggcccgccg tcgtcatcca gcgccctgac caccacggcg tcgagctcgg
    18841 cgccgcgcac gacgtcggcc gggtcggtgc ccggcccgat gacgagggcc tggcagcggc
    18901 cgggcgcggg gacgacctcg gggcggcggg ccaggacgag gtcctccacg cggtgcggcg
    18961 cgctcaggcg gaccatcccg gccccgcagc gcgcggccgc cgaggcggtc aggaccgcgg
    19021 ccccggggta ggtccggctg ccggcccaca ggccgaccac gccgcgggtg tacttgtggt
    19081 cggcgtcgcc ggggacgcgc aggaggcgcc cgaggtcggc gtcggcgggc cgcgaggcga
    19141 cgacggcgcc ggggtccgcg gggacgggca ggccgaggtc ggccacctcg acgcgcccgc
    19201 aggcgccggc cgcgggcggc aggatgtggg cgcccttgag gcaggtgaag gtgaccgaca
    19261 ggtccgctgc caggacgggg cctgccacgg tcccgtcgtc cacgccggcg cccgagggca
    19321 ggtcgaccgc catgacccgg aagggccgcg ccccccgccg ccccgccgcg gccaggggcg
    19381 ccaccagggc ggccgcgcgg gcgcgcaggg ggccggtcgc gccgatgccg gtcaggccgt
    19441 cgatgacgag ggcggtcccg ccggcggcgg cgcgctcgca ggccgccgcg ggctccgggg
    19501 cggggcgcac cccggcgcgc tccgcctccc gcagcgcgcc cgcgtggggg tgatcggtgg
    19561 ccagcgccgc ggtgacggcg cagccgcgcc gggccagcag ggcacccgcc agcagggcgt
    19621 cgccgccgtt gtgcccgccg ccgaccagga ggaggacgtc gcggccggtc gcgcggcccg
    19681 cagcgccgcg cagctcgcgc gcggccgcga gcgcgagggc gcgggcggcc aggtgcatgt
    19741 agcggtccgt cgaggcggtc aggccgcgct cggcccgggc gacggcctcg gcgcggtagg
    19801 cggtggccgg cgagagggtc ggggaggtgg gaggcgcggt gctcactgtg ctcacggccc
    19861 caatagtgtc accgggcggc gcctgcgcgc ggcctcacgc gcccggtccg gccgcgggcc
    19921 ggcgatctcg tggcctgcgg cgcggagccg gaccggcctc ggcgcgggtt ccgaccggtc
    19981 tcggcgcggg agggcacact ggcgggtgtg attctgggaa tcggcacgga cctggtcgcc
    20041 gtcgggaggc tggaggcccg cctcgtatcc gtcccggcac tggccgggcg cctcttcacc
    20101 ccccaagagc gcgccgcctg cgccgggcgc gccacctgcc tggcgggccg gttcgcggcc
    20161 aaggaggcgg tggtcaaggc gctcggctcg gccctggcgg aggcgggccg gggcgcgccg
    20221 agcggctggc gctacaccga cgtcgaggtc gtctccgccc ccggcgcccc gccgcggctg
    20281 gccctgcacg gggtcgcgcg ggccaccgcg gccgggctgg gggtcgccgg ctggcgcctg
    20341 tccctgacgc acgacgacgg ccgggccctc gccttcgtca tcgccgaggg cggtggcgag
    20401 ggccctgacg ccccggggag ccgcgccgcg ccgggcgccc ccgtcactcc acggtgacgg
    20461 acttggccag gttgcgcggc tggtcgacgt ccaggccctt ggccttggcc agggcggccg
    20521 cgaagatctg cagcgggacg accgtgagca gcggccacat gagcgtcggc gtggccggga
    20581 cgcggatgac gtggtcggcg aagggcgtga ccgcctcgtc gccctcctcg gcgatgacaa
    20641 tggtgcgggc gccgcgggcg cggacctcct ggatgttgga gatgaccttg tcgtgcagga
    20701 cggggcggcg cggcgtgggc acgatgacga agaccggcag gccgtcctcc accagggcga
    20761 tggggccgtg cttgagctcg ccggcggcga agccctcggc gtggacgtag gcgagctcct
    20821 tgagcttgag cgccccctcc agggcgacgg ggaagccgac gtgcctcccc aggaagagga
    20881 aggaggcccg gtccgccagc attgcgccga gctcttggac gtcctcctcc tgctcgttca
    20941 ggagccgctg gatcctggcg ggcatccgct cgagctgggc caggtagtcg gcgacctcgt
    21001 cgtgccactt gttgccgcgc agctgggcca ggtagaggcc cagcaggtag caggcggtga
    21061 tctgggcgag gaaggccttg gtggaggcca cggcgacctc cggcccggcg tgggtgtaca
    21121 ggacggcgtc ggcctcgcgg gcgatggtcg agccgtaggt gttgacgatc gccaggacgc
    21181 gcgagccctg ctcgcgggcg tggcgcaccg cctggatggt gtccatggtc tccccggact
    21241 gggagatggc cacggtgagg gtcttctcgc tcacgatggg gtcgcggtag cggaactcgt
    21301 gggcgagctc gatctcgacg ggaatgcggc accagtgctc gatggcgtac ttggcgacgt
    21361 gcccggcgta ggcggcggtg ccgcaggcga cgacgataat cttgtccacg ctgcgcagca
    21421 cggaggcctc gatgcgcatc tcgtccagga tgaggtcgcc cgcctcgttc acgcgtccgc
    21481 gcagggtgtc ggccacggcg gtgggctggt cgtggatctc cttgtccatg aaggtctcgt
    21541 agccgccctt gacggcggcc gaggcgtccc aggagacctc ccaggcggcg ggctcgacgg
    21601 cggtcccgtc ggcgtcccac acgcggacct cgtcggcggt cagcagcagg acctggtcgt
    21661 cgtcgacctc ggcggcgcgc ctggtgaagg cgacgaaggc ggccacgtcg ctgcccagga
    21721 agttctcgcc ctcgcccagg ccgatgacca gggggctgga gcggcgggcg gcgacgatgg
    21781 cgccgggggc cagagatgtg acggccagga gcgcgaaggc gccctccagg cgggaggtga
    21841 ccgcgcgcat ggactccacg agcagggcgg cgacgccggc ctcctccagg gcctcgccgg
    21901 cggcgtcgag gcgggcggcc aggtcgaggt cgagcaggtg ggcgacgacc tcggtgtcgg
    21961 tggccgacag cagctcgcgg ccggctgcct ccacctcggc gcgcagggag cggaagttct
    22021 caatgatgcc gttgtggacg acggcgacgc tgccggcccg gtgcgggtgg gcgttgaccg
    22081 tcgtcgggcc gccgtgggtc gcccagcgcg tgtggccgat gccgcagacc gcggggggag
    22141 gcggggcggc cgccagcgcc ccgcgcaggt tgtcgagctt gcccgcggcc ttgacgacgt
    22201 cgagcccgcc ggggcccacg agggcgacgc cggcggagtc gtagccgcgg tactccaggc
    22261 gccccaggcc gtccatgagg acggccaggg agcgctcgga cggggtcggg gggccgacat
    22321 ggccgacaat tccacacatg gggatgatgg aatcacgccc gcccctacga gacaacgggt
    22381 catcctccgt atcacgtgag acctgcggca ttccggggcg cacggtgctc gcgcctgagc
    22441 ggcgcccgtg cggatgcgtc agacttgggc ggtgagctcc gcgccgtccc cctacatcga
    22501 gttcagccgc aaccagtggc gcgcactcgc ctcgaccact cccctgcccc tgacccaggc
    22561 cgacgtcgag aagctgcggg gcctggggga cccgatcgac ctggcggagg tcgacgtcgt
    22621 ctaccggccg ttgacggcgc tgctggagga ctacatcgcc acctcccgcg agcgggcccg
    22681 gcgcatctcg gacttcctgg gggtgggccc gcacccgacg cccttcgtca tcgccgtggc
    22741 cggctcggtg gcggtgggca agtcgacgac ggcccgcctc atcgcccacc tgctggcccg
    22801 cttcccccag accccgcagg tcacgctggt gaccaccgac ggcttcctgc tgcccaacgc
    22861 ggtgctggag gagcgcgggc tcagcgcccg caagggcttc ccggagtcct acgaccggcg
    22921 ggccctgctc gacttcgtcg cggcggtcaa gtcgggggcc gagcgggtcg aggcgccggt
    22981 gtactcgcac accgtctacg acatcgtgcc cgggggctcc gtcgtggtcg agcggcccga
    23041 cgtcctggtg ctggaggggc tcaacgtcct ccagccggcg ccgcgccccc gccgggtcga
    23101 ccgcggatcc ggcccggcgg agcgcgaggc ggacgccccg gcgctggccg tcagcgattt
    23161 catcgacttc tccatctacg tggacgccga ccccgaggat atccgccgct ggtacctcga
    23221 ccggttcctc acgctcaagc gcacggcctt cagagaaccg ggctcctatt tccagcgcta
    23281 tgccactatc cgcgacgaca tcgccgtggc cgcggccaac gaggtctggg agagcatcaa
    23341 cctggtcaat ctgcgcgaga acatcgctcc gacccggggg cgggccaccc tggtgctgca
    23401 caaggactcc cagcaccata tgcaccgggt tctgctgcgt aagatctgag tcctgcccga
    23461 atactgtctg ggtgccgccg ggtcggcgcc gccccggcgg caccgcgcat tcccccgccc
    23521 ccctcggaac cactgcccat ttccgcccca cggccgagtc
//
