LOCUS       NZ_CP066049.1          23028 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP066049.1 Actinomyces naeslundii strain FDAARGOS_1037
            chromosome, complete genome.
ACCESSION   NZ_CP066049
VERSION     NZ_CP066049.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:38:28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2049267
            Orig. end    :: 2072295
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23028
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2059267:2062295]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13028
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23028
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23028
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="5"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             704..1453
                     /locus_tag="ctg1_1658"
                     /transl_table=11
                     /translation="MSTLQIKNLHVQVATNDGPKPILKGVDLTIDSNQVHAIMGPNGSG
                     KSTLAYSIAGHPDYEVTDGEVLLDGVDLLEMSVDERARAGLFLAMQYPVEVPGVTVANF
                     LRTAKTAIDGEAPKVRQWVGQVNQAMKNLRMDPAFSQRDVNAGFSGGEKKRFEILQMEL
                     LRPRFAVLDETDSGLDVDALRIVSEGVNRLHDETDAGFLLITHYTRILRYIKPDYVHVF
                     VDGRVAEAGGPDLADRLEEEGYDRYLA"
     CDS             1613..2965
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1659"
                     /sec_met_domain="Aminotran_5 (E-value: 2.9e-93, bitscore:
                     310.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSTAPSTGARSASALSAEEVAAIRAGFPYLERPARNSGALAYL
                     DWAATSQKPASVITTEADFYRISNGAAGRSTYQLADEATATFEDARDAVAAFVGARGSE
                     LVFTKNATEAINLVALAIGHASLGRPASRGGGAAAADDPARRLIIGEGDEVVVTRAEHH
                     ANLVPWQELCARTGATLRWLDLTEDGRIDTGTLDVITERTRVLALTHASNVTGAISPLD
                     LIVPRAQQVGALVVLDTCQSAAHLPLDFRALKATGVDAMVLSSHKMLGPTGIGALVATE
                     ELLAAMPPVLTGGSMIEVVTMESSTFMSGPPRFEAGSQPLAQAAGWRTAVEYLAGIGLD
                     RLHATEQVLTRQVLEGLTQVPGLRLVGPTDTTDRLGVVAFSIEGVHPHDVGQVLDAAGV
                     AVRTGHHCAQPIHQRFGIHASSRLSFGACSTPEEVDRFLSAIADVRRYFQR"
     CDS             2968..3465
                     /locus_tag="ctg1_1660"
                     /transl_table=11
                     /translation="MNELDQLYQQVILDHSRERHGSGALDAPDATSHQVNPTCGDDVTL
                     GVRVKDGKIEAVGWEGDGCSISQASISVMHDLVNGADLATVARLEADFDTLMHSRGKGV
                     DDAVLDDLEDGAAFEGVSKYPNRVKCALLGWMALKDALAKSGVALPSVEQAGPEYPDRP
                     TA"
     CDS             3500..3895
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 72.8; E-value: 6.4e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1661"
                     /sec_met_domain="FeS_assembly_P (E-value: 2.7e-21,
                     bitscore: 72.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENPTEVPVGTDNPMAAQQPPAPVASTEGVDVAAIEEALRDVID
                     PELGINIVDLGLLYGVSIEPDGTVVLDMTLTTAACPLTDVIEEQAQQALSLIADNVRIQ
                     WVWLPPWGPDKITPEGREQLRALGFNV"
     CDS             complement(3921..4940)
                     /locus_tag="ctg1_1662"
                     /transl_table=11
                     /translation="MAGTRAAQRRATQTALITEARQRFANEGYTAVRLSDVVDALGMTK
                     GALYHHFTGKHDLFRAVVQQVQQEVADRVQAAARPGADPWEELIAGCKAFLASYSNPET
                     RQIMLIDAPTVLGWREWKEMDGAYSERLLTEVLTSLMENGTLVSRPVEPMVHLLSGAMN
                     EAALWLAETDSPTALKDTMGALQCMLGSLRADGIAPSAEASSVDGMSERLPSSDNVVLK
                     GIREEPNPEDGTRVLVDRLWPRGVSKERADLDEWAKDATPTTELRRAFHSGEMPWPQFV
                     EAYRAELTERPEAVAAVEHLRDEALKGRVTLLFAGHDHVHCHARVLREAVLGVEEDLA"
     CDS             5034..5453
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyoxalase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1663"
                     /sec_met_domain="Glyoxalase (E-value: 1.9e-10, bitscore:
                     38.3, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIRDNYPIIVTDRKDEARDFWRRFLGFRPVFDSSWFTLMTDEGS
                     GSSIAFMTPDHPSAPPGPDAFAGTGACFELEVDDAVAAHAELTGRGLAVTYPLTDEPFG
                     QRRFGFADPSGLWIDVVEQVAPRPGYWDTYLRGTG"
     CDS             complement(5488..7116)
                     /locus_tag="ctg1_1664"
                     /transl_table=11
                     /translation="MTSVPQSLKAIWQSAHLALCQERNWLVALPVVTGLMTALLAPSYG
                     DTYASPEDLARAVASAQVSDTSTFLYGGLSDTAGVVQVATWELGGLTCLVLSIVVALRS
                     VALTRTEEDLGRAELLRSTGAGSIASLVGQGLVLVLQCLLLGAGAGAGLLALEEADDTD
                     AAAYGAVLASTLLAVACATLVIAQMIPDAATGRAVALGVVGLMYTGNGMRASKDWNWAG
                     WASPFRLRTAADPGGENSWGPVLIAVAASIMVLALAGVLTSHRDLGQGLVQLPARRSPS
                     LRVGGPLTLAVRLSRSQCLAWAFLVSLVAGVLVSMGGDVVDLARQGGISGGSLGSLLAG
                     DDPGEAFLRYIGQLAGALAAAQGVSLALRYSGDERSGRLEMVVSTGNRPLRILLSSWLV
                     AALGSGLTLICATVAAGYVGRSELDTDLIDAVRLVAGQWPAALASAAIATALCGAWPRG
                     RGLAWGPVLVGLGIAQLGGVLDLPKRIRDAGPFAQAGENGSLWLLAVATACLATAAFGV
                     TRRDMSLIAASRRSLTRQTSSSAIP"
     CDS             complement(7113..8120)
                     /locus_tag="ctg1_1665"
                     /transl_table=11
                     /translation="MPTTTASPTASVLPARHHSPAIDASGLVKTFGPLRALDGLDLKVE
                     TGQIHGFLGPNGSGKSTTIRVLLGMYRRDSGMVQVLGMDPHRDAEHITRRCTYVPGDVA
                     LWPTLTGAQTLDALAALRGGRDRAREAELIEAFRLDPHKPVRSYSKGNRQKVMLVAALA
                     APCDLVILDEPTSGLDPLQAEVFVDAVRDAAGQGRTVLMSSHIMAEVDRLCDSVTIIKD
                     GRTVESGRLEELRHLRASRITCVLPPEQSPAPRRHRWSRWLRRERGAQRSPTKDPTRVA
                     LLRPDADGLLSVSVPTDRVPATLRQLLAAGAQEVTCTPASLDEVFLQHYEAAAR"
     CDS             complement(8190..9059)
                     /locus_tag="ctg1_1666"
                     /transl_table=11
                     /translation="MIQMPCETVPMRVAEIAELTGTTVRTVRYYHSLGLLPVPDERGGW
                     RDYDLGHVARLSRIRWLVQAGVSLETIKRVLDEPEATGVEQIDDAPVAEAAGTRPPAGS
                     VVEDLAGALSAVEDHLAEVTRQRDMLAGLLERARTGSTVSPMSPRMAAFFDRLEQAAPD
                     EATRCAVRKERDLTDLACYRGQMPPEAEFLFVDPDPRYDAESLALYSQDPAELSDAQIE
                     QRARDMVSRLEARLTPEHLADLANSVDTEAVQALFRLIATTGYPDARLIRTLEREFLTA
                     IDRWRLSE"
     CDS             9220..9969
                     /locus_tag="ctg1_1667"
                     /transl_table=11
                     /translation="VNGTRANLQVGDMLQGSAGTLSVRGCLLFKEWDAQDRCFYYWEEW
                     QLVGGSNADTWVELDHDPGEILFYEPVRLQEAIEPWALTVGQRLQLTINGTPHQALVEE
                     VTTGTLENAIGSPVCPLNIGETMTYVELRLTDPAGVTSRLTIDSHRFRDLLAYRKTSLS
                     TSQQKQLFGRVLCNSRPVAGRTGRNIGCAIVAAIVSVVLAVGLFSACSSSSRSTGGADS
                     SSTSDSSSSRTYRHRPVYGGGGGGVGK"
     CDS             10001..10429
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1668"
                     /sec_met_domain="AdoMet_dc (E-value: 4.6e-23, bitscore:
                     78.8, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSRRRASADGDLAPFVGCLPRCYRARVSAVSLCSVSYKISGAEP
                     HVLNDLPTVESILLDAARKAGLTAVSSAHHRFEPQGLSAVVILSESHIAAHTWPESGDG
                     YVTLTSCRTLTPAQIEAVGEMVRQRLQAQQVISSGITL"
     CDS             complement(10390..10791)
                     /locus_tag="ctg1_1669"
                     /transl_table=11
                     /translation="MWDGSCLMVNIGSVYVLDLNGIRSTIDLQLQGLAHLERERIDHRL
                     NRNRLVKNNHIGISIDLEPELFAVVVDQAPLLPPSEAPASLIPPFQDNSPHDGVGVTLL
                     PQGTPKRLADSQITSDAHSVIPELITCWA"
     CDS             11246..11491
                     /locus_tag="ctg1_1670"
                     /transl_table=11
                     /translation="MSLMTIAHHSSVDLNWQSLLSTIVYAVLGVVLLMVFALLVNRIFR
                     LDLRRELIEDQNIGLGVAFAGTALAIAIIIAATILS"
     CDS             11502..13028
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1671"
                     /sec_met_domain="Spermine_synth (E-value: 1.8e-37,
                     bitscore: 125.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHGRIGRRENVALFTAALLAAIGGLIYELILGTAASYLLGDSVL
                     SFSLATGITLFGMGIGSLLVNRFRAAPAVVFGVSEVLLGLIGGNSVLLLYLAFGRTRLH
                     WVVFGGISLTIGILIGLEIPLLVRTFAAFGRRSTSELLGKVMAIDYFGSLVASLVFPLV
                     LLPQLGLMRGAYLVGALNVLVAVLVLLQVRTPRKILWAATAAVVALVGMFAAANRIERS
                     VEALTYNDPVVYYQQTAYQKVVLTDYQDDLRMYLNGQLQFSSLDEARYHETLSASAMTS
                     VKDPAHVLVLGGGDGLLAREILRYPSVKDVTIVDIDPGVTELARSNRLLKDLNKASLSD
                     PRVNVVNDDAFTYVRDSRATYDVVLVDLVDPSNEKLAKLYSTEFYRNVEARLAPEGVMV
                     TQATSTFFSPHAFSTVASTVATSQPDRQILPFSTNIPSFGEWGFVLSTRTPQNLISQPL
                     PEGLTYQDRETLEFIMRTKPARTETMEPSTLLHPRIVEVYNRDMRQWRYY"
     CDS             complement(13126..13485)
                     /locus_tag="ctg1_1672"
                     /transl_table=11
                     /translation="MTATNHDKSPRLRLSGRNIAGACLAVCGLLIIIWGGTLKSVNVTD
                     PDFMSFAVSGLVTVAAGACLATALPRAARVALIWLATLASMLYLLILGMAVIVSLMSCV
                     VIAGIAVWLTIRILR"
     CDS             complement(13540..14049)
                     /locus_tag="ctg1_1673"
                     /transl_table=11
                     /translation="MTKALIVVESYFGNTRAIAEAVAAGLIEGSVDAQVVDVSQAPSAL
                     PADLDLLVLGAPTHNRGLPTATSRAKACEQAGSGEASHGIGGWLETTAIPASTGAAAFD
                     TVISKGWLSGSAAKAIAKALQRHQGRRTVSVRSFVVTASKGPLADGEKTDAHSWGRELV
                     ASANTR"
     CDS             complement(14240..15148)
                     /locus_tag="ctg1_1674"
                     /transl_table=11
                     /translation="VSFNRDIQIDPNRVQTRSGGGRGAMIGGGSILTVIAVVLISQLTG
                     VDLSSMLGAQQQNGATRPTASSIDTSVCTSGDSANKYTQCRMVATAESLDAVWTDQLPA
                     QAGLKYAKPEFVLWDGTQISSACGNASSAVGPFYCSGDQTVYLDMSFFSEMEKSLGATD
                     TPLAEEYIVAHEFGHHIQHLTGQMAKADRSGSGATSDSVRLELQADCYAGIWVNHASST
                     PDPETGKPFLSRPSSEEISGALGAAEAVGDDHIQERAKGHVDSDTWTHGSSEQRVRWFT
                     TGMNSGSVQACNTFAVDASKL"
     CDS             15306..16370
                     /locus_tag="ctg1_1675"
                     /transl_table=11
                     /translation="VLYDLLYKTVLTRIDPELIHDVCMDAIELTGKVPFIRDVVRQVCG
                     RRPVFPVPSANQGGPFARPVPGVLGLAAGMDKEGQAVEGLDMLGFGFIEVGTFTARAQG
                     GNDKPRMWRYPQMRAVRNRMGFNNSGADEAAKRLRALRRTPRGRSIVVGANIGKTKVTP
                     LEDAVEDYRYSAKAVARWVDYLVVNVSSPNTPGLRSLQSVEALRPILEAVREAADQAAM
                     RHVPLLVKIAPDLADEDLDAVADLVLDLGLDGVVATNTTIDHDLGDGGLSGAPLLPRSL
                     EVVRRLRSRLGEGPTIIGVGGISSIMDAELMLDAGADLLQAYTAFIYNGPAWPGRINRA
                     LATASAGSAVRALR"
     CDS             complement(16382..17398)
                     /locus_tag="ctg1_1676"
                     /transl_table=11
                     /translation="MEHTVGYRHLGSSGLKITEITYGNWLTHGSQVEAGTAIECVHTAL
                     DLGITSFDTADVYANTVAEEVLGRALAGRRRESLEVFTKVYWPIGPKGPNDVGLSRKHI
                     MEGINGSLTRLGMDYVDLYQAHRYDHETPLEETMQAFADVVRAGKALYIGVSEWTAEQI
                     RAGQELATQMGFRLVSNQPQYSALWRVIEDRVVPTSQDLGLGQIVWSPMAQGVLSGKYL
                     PGQEPPAGSRATDDKGGRQMISRWMRDDVLTAVQALRPIAQDLGLTMPQLAIAWVLRNP
                     AVSSAIVGASRPEQLADTVRASGVHLDDDVMAAIDIALGDVVERDPSLTSSPEKRPA"
     CDS             complement(17471..18079)
                     /locus_tag="ctg1_1677"
                     /transl_table=11
                     /translation="VSLFKKRSQTPEPEPAAEPAPKPVGKGRPTPKRRDQQAKNLHPVV
                     PKDRKAAKREARAARDEAWKRQSEAMVTGDEKYLPSREKGPVKRYIRDYVDARFSLGEF
                     FMPLIFVLLILSFGFNHILPQYPVISFYAVLAMNGYLLLAIVDAVWCWNRLRRRLHKKF
                     GEERVKNEGMIFFYIMSRCFMLRRWRRPATLVKRGQYPS"
     CDS             18121..19509
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1678"
                     /sec_met_domain="Peptidase_M20 (E-value: 5.8e-26, bitscore:
                     88.7, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITVDAVRNAVHTSMPAIVSDLTDLVTIPSVSASSHDQSQVRRSA
                     EAVASLLRDSGLDAEILSVPAPDGAPGRPAVLAHKAGPQGSPHVLLYSHHDVQPVGDPT
                     GWDQADPFTAERRGERLFGRGTADDKAGVITHAHALRTLASLADGELPCSVTVFIEGEE
                     EVGSPSFESFLTTYRDRLASDVIVVADSSNWKVGTPSLTTLLRGVVQVDVRLDMLDHAL
                     HSGQYGGPVLDAATAMCRLIASCHDEAGDVAIAGLVSRPQADADFPDYPEADFRADAGV
                     LDGVELVGTGDLTARLWTKPSLTLIGMDVTPLDLAGNVLTPSCTARLSLRIAPGQDPAE
                     AQAALVAHLEKHVPFGGRLTVEGREAGPAFDGSETTPASEAARWALSTAWSTEAVNIGQ
                     GGSIPFIATLKETFPEAQVLVTGIEDPDTRAHSENESMHLGELEHIVVAEALLLARLGD
                     AIAS"
     CDS             19550..20800
                     /locus_tag="ctg1_1679"
                     /transl_table=11
                     /translation="MRVLLAPGGLWPEPAGVPLAGLGRGLPAGRVAACLARGWQAARPS
                     DALTLMPMSDGGPGSSQAIAPERIASREVIQAQGPLGQVREVDLVRMAPSPSNPGGRRP
                     GEGGTWFLDAARLLAVPPDPDKAAQEALRGSSHGLGQVIGVAVDRMAPSDTLLVGLSRA
                     AVHDGGAGVLDALGGASAAAELLAGRSIGLVLADDIALGGLSGAGAALTRIAALSPRQA
                     QELDRRACAAAAEAVSTAEAGAPQVSSRGQRMLPVISALDEAALPSSATADLGGPPRLS
                     ASTWGTGAAGGSAMVLRALGAWARPGARVMAEILGLSEAVSGQDLVVTASGELYDVPAD
                     GVVGVVGHHAASQALPVAMVCGRCVTTRGELAGAGISNAYSLQEPHAAESWDAVGSDAL
                     QDRLTDMGARLARTWSR"
     misc_feature    19577..19579
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(20899..21069)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1680"
                     /sec_met_domain="Peripla_BP_3 (E-value: 7.7e-11, bitscore:
                     39.9, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPPLTTVRQPVGSICRAAVSTLLAQLDGERPTDTEMLFAPDLI
                     VRDSTAAAFID"
     CDS             complement(21066..21911)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LacI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="regulatory (smcogs) SMCOG1013:Bacterial
                     regulatory proteins, lacI family (Score: 58.2; E-value:
                     1.7e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1681"
                     /sec_met_domain="LacI (E-value: 7.2e-17, bitscore: 58.2,
                     seeds: 22, tool: rule-based-clusters)"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4e-17, bitscore:
                     59.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQRLTLTDIADQAGVSTATVSRVLNGKSNVADSTRRQVLAALDI
                     LGYERPESVHQSSRGLMGLIVPELSNPIFPLFAQQIEQLLAPSGHTPLLCTQTPGGISE
                     DEYIEMLVDRGVAGIIFVSGRHADTTGDVTRYQRLRERGVPLVTVNGNAPTIKAPGFAT
                     DDRRATRMAVDHLIALGHQRIGLAMGPMRMVPAQRKRSGYEDAMREGLPQEPLRIVETL
                     YTYEGGISAALHLLEQGCTGIVCSSDVMALGVVHGVRQTGRSVPHASPSSATTTHRSFP
                     "
     CDS             complement(22111..23028)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 60.7; E-value: 5e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1682"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.1e-17, bitscore:
                     60.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSSKTVSKSSENVLPAENHMPFSRWFREIGWRHVVGVVALVFA
                     AFPVLYVISASLNPLGTVASTGLIPTKVSLVNYQNLLAGARGPFLRWYLNTIIICSVVA
                     TAQVFLSLLGAYAFSRFRFTGRRGGLLALLLIMMFPAILSMIAIYTMISDIGQVVPSLG
                     LNTLAGYSLALMGGALGQVWLIKGTFDTIPRELDEAAIIDGCTHWQVFRIILLPTLKPI
                     IATTFLLAFVGVISEFLLGSIILTDNSQKTLAVGLYGMLVGDRSNNLGIFAAGAVLTMA
                     PVIALFQYLQRYIVGGSISGAVKG"
ORIGIN
        1 aaccaccggg tgaaggtctc cggccggggt gtcctcaagc acgtcgtcgt cagcctcggc
       61 ggagacgtgc gcatctgccc cgacctggga ttctccggcg agggcggcca catcgacgca
      121 tacggcgtct acttcaccga tgcgggccag caccaggagc accgtcccta cgtggcccac
      181 accgagcccc actgctactc ccgcgtcacc tacaagggag ccctccaggg ccaaggtgcg
      241 cacgccgtat gggtggggga ctgcctcatc ggtcaggcag cccgtggcac cgacacctac
      301 gagctcaacc gcaacctcgt cctgaccgag ggcgccaagg ccgactcggt accgaacctg
      361 gagatcgaga acggcaacat cgagggcgcg ggtcacgcca gcgccaccgg ccgcttcgac
      421 gaccagcagc tgttctacct gcgtgcccgc ggcatccccg agaccgaggc ccgtcgcctc
      481 gtggtcctgg gcttcttcaa cgagatcgtc gccgagatcg gtgtcgacga ggttgaggag
      541 cgcctcatgg ccgccatcga gaaggagctc gagctcaccg gcctcatcgc cgcccgcacc
      601 gaccaggacc ccgtcgccgt accgacagcc gagtgattgg ccggacccca cagcggtccg
      661 cctactcgtc accagaccca ttaccagccg aaagaaacgt cgcatgagta ctctgcagat
      721 caagaacctc cacgtccagg tggccaccaa tgacggcccc aagcccatcc tcaagggtgt
      781 cgacctgacc atcgactcca accaggtcca cgccatcatg ggccccaacg gctcgggcaa
      841 gtccaccctg gcctactcca tcgccggcca ccccgactac gaggtcaccg acggcgaggt
      901 cctcctcgac ggcgtcgacc tgctcgagat gagcgtggat gagcgcgctc gcgccggcct
      961 cttcctggcc atgcagtacc ccgtcgaggt ccccggtgtc accgtggcca acttcctgcg
     1021 caccgccaag accgcgatcg acggtgaggc ccccaaggtg cgccagtggg tcggtcaggt
     1081 caaccaggcc atgaagaacc tgcgcatgga tcccgccttc tcccagcgcg atgtcaacgc
     1141 cggcttctcc ggcggtgaga agaagcgctt cgagatcctc cagatggagc tgctgcgccc
     1201 ccgcttcgcc gtcctggacg agaccgactc cggcctggac gtcgacgcgc tgcgcattgt
     1261 ctccgagggt gtcaaccgtc ttcacgacga gaccgacgcc ggattcctcc tcatcaccca
     1321 ctacacgcgc atcctgcgct acatcaagcc cgactacgtc cacgtcttcg tcgacgggcg
     1381 cgtcgccgag gccggcggcc ccgacctggc cgaccgtctg gaggaagagg gctacgaccg
     1441 ctacctggcc tgatcggcct cgtccgtgca ggagccgatg acggcgcgcc gatcagaggc
     1501 gtcgtcgtcg gtctccgcac gagcaagggg tactaaggtt cttcgtgatc tcagcccgca
     1561 gccgtcggcg accatgcccg gtacagctcg catcgaatcg gaaaggcacg ccatgaccca
     1621 gtccacggcc ccatccaccg gggcgcgttc cgccagcgcg ctcagtgctg aggaggttgc
     1681 cgcgatccgc gccggtttcc cctacctgga aagacccgcc cgcaacagtg gggccctggc
     1741 ctacctggac tgggccgcca caagccagaa gccggccagt gtcatcacca cggaggccga
     1801 cttctaccgc atctccaacg gtgcggcggg gcgctcgacc taccagctcg ccgacgaggc
     1861 caccgccacc ttcgaggacg cccgcgacgc cgtcgccgcc ttcgtcggtg cgcgcggcag
     1921 tgagctcgtc ttcaccaaga acgccaccga ggccatcaac ctcgtggccc tggccatcgg
     1981 gcacgccagc ctgggccggc ctgcctcccg cggtggcggg gccgccgcgg ctgatgaccc
     2041 ggctcggcgc ctcatcatcg gggagggcga cgaggtcgtc gtcacccgtg ccgagcacca
     2101 tgccaacctc gtgccctggc aggagctgtg cgcccgcaca ggcgccaccc tgcgctggct
     2161 ggacctgacc gaggacgggc gcatcgatac cggcacgctg gacgtcatca ccgagcgcac
     2221 ccgcgtgctg gccctgaccc acgcctccaa cgtcaccggt gcgatcagtc cgctcgacct
     2281 catcgtgccg cgtgcccagc aggtcggtgc gctcgtcgtc ctggacacct gccagtccgc
     2341 cgcccacctc ccgctggact tccgcgcgct gaaggccacc ggcgtggacg ccatggttct
     2401 ctccagccac aagatgctcg gccccaccgg tatcggcgcg ctcgtggcca ccgaggagct
     2461 gctggctgcg atgccgccgg tgctgaccgg aggctccatg atcgaggtcg tcaccatgga
     2521 gtcgtcgacc ttcatgagcg gcccgccccg tttcgaggcc ggcagccagc cgctggcgca
     2581 ggccgcggga tggcgcacag cggtggagta cctggcagga atcggcctgg accggctcca
     2641 cgccaccgag caggtgctga cccggcaggt gctcgagggt ctcacccagg tccccggact
     2701 gcgtttggtc ggcccgaccg acactaccga ccgcctgggc gtggtcgcct tctccatcga
     2761 gggagtccat ccccacgacg tcggtcaggt cctcgacgcc gccggcgtcg ccgtgcgcac
     2821 cggtcaccac tgcgcccagc cgatccacca gcgcttcggc atccacgcct cctcgcgtct
     2881 gtccttcggg gcctgctcca cgcccgagga agtggaccgc ttcctgtccg ccatcgctga
     2941 cgtccgacgc tacttccaga ggtgagcatg aacgaactcg accagctcta ccagcaagtc
     3001 atcctcgacc actcccgcga gcgccacggt tccggcgccc tcgacgcccc ggacgccacc
     3061 agccaccagg tgaaccccac ctgtggtgac gatgtgactc tgggggtgcg cgtcaaggac
     3121 ggaaagattg aggccgtcgg ctgggagggg gatggatgct ccatctccca ggcctccatc
     3181 tccgtcatgc acgacctcgt caacggcgcc gacctggcca ccgtcgcccg cctcgaggcg
     3241 gacttcgaca ccctcatgca ctcgcgcggc aagggcgtcg acgacgccgt cctggacgac
     3301 ctcgaggacg gtgccgcctt cgagggggtc tcgaagtacc ccaaccgcgt caagtgtgcc
     3361 ctgctgggct ggatggctct caaggacgcc ctggccaagt ccggcgtcgc cctgccttcc
     3421 gtcgagcagg caggccccga gtatcccgac cgtcccactg cctgatcacc gtctgacctc
     3481 cgaggaagaa ggagaagcca tgagcgagaa ccccaccgag gtgccggtcg gcaccgacaa
     3541 ccccatggct gcccagcagc caccggcccc cgtcgccagt accgagggcg tcgatgtcgc
     3601 cgccattgag gaggccctgc gcgacgtcat cgaccccgag ctcggtatca acatcgttga
     3661 cctcggcctg ctctacgggg tgtcgatcga gcccgacggg accgtcgtgc tcgacatgac
     3721 cctgacgacc gcggcctgcc ccctgaccga tgtcatcgag gagcaggctc agcaggcctt
     3781 gtccctcatc gcggacaacg tccgtatcca gtgggtgtgg ctgccgccgt ggggaccgga
     3841 caagatcacc cccgagggcc gcgagcagtt gcgcgccctg ggcttcaacg tctgagaccc
     3901 cgaccctgcc gaagacgccg tcaggccagg tcctcctcga cgccgaggac cgcctcgcgc
     3961 aggactcgcg cgtggcagtg gacgtggtcg tggccggcga acaggagcgt cacccgtccc
     4021 ttcagagcct cgtcgcgcag gtgctcgacg gcggcaaccg cctcgggccg ctcggtgagc
     4081 tcggcccggt aggcctcgac gaactggggc cagggcatct ctccactgtg aaaggcgcgg
     4141 cgcagctcgg tggtcggggt ggcgtccttg gcccactcat cgaggtcggc acgttccttg
     4201 gacacgcctc ggggccagag ccggtccacc aggacccgtg ttccgtcctc ggggttgggc
     4261 tcctcgcgga tacctttgag caccacgttg tcagaagaag gaagtcgctc gctcatgccg
     4321 tcgacgctac tcgcttctgc tgacggtgcg atcccatcgg ctcgcagtga accgagcatg
     4381 cactgcaatg cacccatggt gtctttcagc gccgttggcg agtcggtctc agccagccac
     4441 aacgcggcct cgttcatcgc cccggacagc agatgaacca tgggttccac tggtcgggaa
     4501 acgagggtgc cattctccat gaggctggtc agcacctccg tcaggagcct ctcggagtat
     4561 gccccgtcca tctccttcca ctcgcgccac cccagcaccg tcggtgcgtc aatgagcatg
     4621 atctgccggg tctcgggatt gctgtaggag gcaaggaacg ccttgcagcc tgcgatgagc
     4681 tcctcccacg gatccgcgcc cggccgggcc gctgcctgaa cccggtcggc gacctcctgc
     4741 tgcacctgct gaacgacggc ccgaaataga tcgtgcttgc cggtgaagtg gtggtagagc
     4801 gcacccttgg tcattccgag agcgtcgacg acgtcgctta gccgcaccgc ggtgtaaccc
     4861 tcgttggcga agcgctgccg cgcctcggtg atgagtgccg tctgcgtcgc cctgcgctgg
     4921 gctgctctcg ttcctgccat gaagcacctc gacaattgac ataccaaaag tatgtgaact
     4981 agtttgacat accaatggta tgcgaatcct tcgacggcgc ctgggaggcg acaatgcgga
     5041 tccgagacaa ctacccgatc atcgtcactg accggaagga cgaagcgcgg gacttctggc
     5101 ggcgcttcct cggcttccgt cctgttttcg acagttcctg gttcaccttg atgacggatg
     5161 agggcagcgg gtcatcgatc gccttcatga cgccggacca cccttctgct cctccaggac
     5221 ccgatgcctt cgccggaacc ggtgcctgct tcgagctgga ggtcgacgac gcagtagcgg
     5281 ctcatgccga gctgacgggc aggggactgg cagtgacgta cccgctcacc gacgagccct
     5341 tcggccagcg ccggttcggg ttcgccgacc ccagcgggtt gtggatcgac gtcgtcgagc
     5401 aggtcgcgcc aaggccggga tactgggaca cctacctgcg ggggaccggc tgaggctcat
     5461 gagatcgctg tcttccagca catcgttcta ggggattgcg gacgatgacg tctggcgggt
     5521 gagggagcgc cgcgaggctg caatcaggct catgtccctg cgggtcaccc cgaaggccgc
     5581 cgtggccagg caggcagtgg ccacggcaag cagccacagg ctcccattct cacccgcctg
     5641 ggcgaaagga ccggcatctc ggatccgctt gggcaggtcg aggacgccgc cgagctgcgc
     5701 gattcccagc cccaccagta ctggacccca agcgagcccg cgtcccctgg gccacgcccc
     5761 gcacagcgcc gtggcgatcg ccgccgacgc caaagcggcg ggccactgtc cggctacgag
     5821 acgcacggcg tcgatcaggt ccgtatccag ctcggagcgc ccgacgtacc cggccgcaac
     5881 cgtcgcgcag atgagagtca gcccggatcc gagagcggcc accagccatg acgagagcag
     5941 aatccgcaga ggccggttcc cggtggagac caccatctcc aggcgtccgg agcgctcatc
     6001 accgctgtag cgcaacgcca gcgacacgcc ctgggctgca gcaagtgctc ctgcgagctg
     6061 gccgatgtac ctcaggaacg cctcgccggg atcgtcgccg gccagaagtg atcctaggga
     6121 tccgccgctg ataccgccct gtcgagccag gtcgacgacg tcgcctccca tcgacaccag
     6181 caccccggcc acgagagaga ccaggaacgc ccacgccaga cactggcttc tgctgagtct
     6241 gacggccaag gtcagcggcc cgcccactct cagcgatggt gagcgcctcg cgggcagctg
     6301 caccagtccc tgaccgagat ccctgtgaga ggtcagcacc ccggccagcg ccagcaccat
     6361 gatgctggcc gctaccgcga tgaggacggg gccccaggag ttctcacctc cggggtccgc
     6421 cgccgttctc aggcggaagg gagacgccca tcccgcccag ttccagtcct tggaggctct
     6481 cattccgtta cccgtgtaca tgagccccac gacccccagt gcgacggcac ggcccgtggc
     6541 ggcgtcggga atcatctgcg caatgacgag cgtcgcacag gccactgcca gcaaggtgga
     6601 ggcgagtacc gcgccgtagg ccgcggcatc ggtgtcgtcg gcctcctcca gagcaagcag
     6661 ccctgcaccg gcaccggctc ccaggagcag gcactggagg accaggacga gtccctgccc
     6721 caccaggctc gcgatggagc cggctcccgt ggagcggagc agctcggcgc gccccaggtc
     6781 ctcctcagtg cgtgtcaacg ccaccgagcg cagggctacg acgatgctca gcaccagaca
     6841 ggtgagccct ccgagctccc aggttgccac ctggacaaca cccgcggtat cggagagccc
     6901 gccgtagaga aaggtcgagg tgtcggagac ctgggccgag gccacggccc gggccaggtc
     6961 ttccggtgag gcgtaggtgt cgccgtagct gggagccagc agggcggtca tcagtcccgt
     7021 caccaccggc agtgccacga gccagttccg ttcctggcag agcgccagat gggccgactg
     7081 ccagatcgct ttgaggctct gcggaacgga tgtcatcgcg ccgccgcctc atagtgctgg
     7141 aggaagacct cgtccaggga cgcaggggta caggtgacct cctgcgcgcc ggcggccagc
     7201 agctgacgca acgtggccgg gacgcggtcc gtgggaaccg agacgctcag caggccgtcg
     7261 gcgtcggggc ggagcagggc gacccgggtg ggatccttgg tcgggctccg ttgggctccg
     7321 cgctcgcggc gcagccaccg cgaccaccga tgacgcctgg gagccgggct ctgctcggga
     7381 ggcagcacgc aggtgatccg ggaggcccgt aggtgcctca gttcctcaag ccgccccgac
     7441 tccacggttc gtccgtcctt gatgatcgtc accgagtcgc acaggcggtc gacctcagcc
     7501 atgatgtggc ttgacatgag tacagtgcgc ccctggccgg ccgcatcacg aaccgcgtcg
     7561 acgaatacct cggcctggag cgggtcgagt ccggaggtcg gctcatcgag gatgaccagg
     7621 tcacacggcg ccgccagcgc cgccacgagc atgaccttct gccggttgcc tttggagtag
     7681 gagcggaccg gcttgtgggg atccagtcgg aaggcctcga tgagctcggc ctcgcgcgcc
     7741 cggtcgcgtc cgccgcgcag ggcggcgagg gcatcaaggg tctgcgcccc ggtgagtgtg
     7801 ggccacagcg ccacgtcacc gggcacgtag gtgcaccggc gcgtgatgtg ctcggcgtcg
     7861 cggtgcggat ccatgcccag gacttgcacc atgccgctgt ctcgacggta catgcccaga
     7921 aggacgcgga tggtcgttga cttccccgaa ccgttggggc ccaggaaacc gtggatctgg
     7981 cccgtctcca ccttcaggtc aagaccgtcg agtgcgcgga gggggccaaa ggtcttgacc
     8041 agccccgagg cgtcgatggc aggggagtga tgccgcgcgg gcagtacgga cgctgtaggg
     8101 gaggcggtgg tcgttggcat gcccccaggg tgaggtgtga cgctgcgtcg tacgcaaagc
     8161 ccacgcggca gcatccaagc aagtgccgct tactcgctca ggcgccatcg atcgatcgcg
     8221 gtgaggaact cccgttccaa ggttcggatg agtcgtgcat cggggtagcc ggtagtggcg
     8281 atgaggcgga agagtgcctg taccgcctcg gtgtcgacgc tgttcgccag gtccgcaagg
     8341 tgctcaggtg tcagccgagc ctccaatcgg gacaccatgt cccgtgcgcg ctgttcgatc
     8401 tgcgcgtctg acagctcggc cggatcctgg gagtagaggg ccagtgactc ggcgtcgtag
     8461 cgaggatccg ggtcgacgaa gaggaactcc gcctccgggg gcatctgacc gcggtagcag
     8521 gccaggtcgg tcaggtcccg ctccttgcgc acagcgcagc gggtggcctc atcgggagcg
     8581 gcctgctcca gccggtcgaa gaaggccgcc atacgcgggg acatcggtga gacagtcgaa
     8641 ccagtcctgg ctcgctccag cagaccggcg agcatgtctc tctgcctggt cacctcggcc
     8701 aggtggtcct ccacggcgga cagggccccg gccaggtcct cgacaacgga gccggccggt
     8761 ggacgtgttc cagctgcttc cgccacggga gcgtcgtcga tctgctcgac gccggtcgcc
     8821 tcgggctcgt cgaggacgcg tttgatggtc tccagggaca caccggcctg gaccagccaa
     8881 cggatccggg agagccgggc cacgtggccc aggtcgtagt cgcgccaacc accacgttca
     8941 tcgggaaccg gaagcagccc cagcgagtgg tagtagcgca ccgtgcgcac cgtcgtcccg
     9001 gtgagctctg cgatctcagc aacgcgcata gggacagtct cacacggcat ctggatcatg
     9061 atccgctcgg atccgattgg tgggggcgga ccatggggag ttcgaaccgt ttgccgggac
     9121 atgcccacgt tgctactgtg cccgcgtgat gacaggcgga ccaggctacg acggcggcag
     9181 cgctgcaccg tctctccctc cgcagacggg agggtcctgg tgaacggcac gcgagccaac
     9241 ttgcaggtcg gcgacatgct gcagggaagt gcgggcaccc tgtcggtcag aggctgcctg
     9301 ctcttcaagg agtgggacgc ccaggaccgc tgcttctact actgggagga gtggcagctc
     9361 gtcggtggca gcaacgccga cacctgggtc gagctcgatc acgaccccgg cgagatcctc
     9421 ttctacgagc ccgttcgtct ccaggaggcg attgagccgt gggccctgac cgtcggccag
     9481 agactgcagc tgacgatcaa cggcactccg caccaggctc tcgttgagga ggtcaccacc
     9541 ggcacgctcg agaacgccat cggctctccg gtgtgcccgc tgaacatcgg cgagaccatg
     9601 acctacgtcg agctgcggct gacagacccg gccggtgtga ccagccgact gaccatcgac
     9661 agccaccgtt tccgtgacct cctggcctac cgcaagacct ccttgtccac ttcccagcag
     9721 aagcagctct tcgggcgcgt cctgtgcaac agccgacccg ttgccggcag aaccggccgg
     9781 aacatcggat gcgctatcgt cgccgccatc gtcagtgttg tactcgccgt cggactgttc
     9841 tccgcgtgct ccagcagcag ccgttccact ggtggagccg actcctccag cacctcggac
     9901 tcgagctcct cacggaccta tcgtcaccgc ccggtctacg gaggcggcgg aggcggagtg
     9961 ggcaagtagg tccgcacccg tcagcgacgg cgtgcccgcc atgcgctccc ggcgccgagc
    10021 gagtgcggat ggggatctcg ccccgtttgt cgggtgcctg ccccgttgct accgtgctcg
    10081 cgtgagtgcg gtgagcctgt gttctgtcag ctacaagatc agtggggccg agccgcacgt
    10141 gctcaacgat ctccccaccg tcgagtcgat tctcctcgac gccgcccgga aagcgggact
    10201 gactgccgtc tccagtgcgc accaccggtt cgagccccag ggcctgagcg ccgtcgtcat
    10261 tctatccgag tcgcatatcg ccgcccacac ctggcccgag tccggcgacg gctacgtgac
    10321 gctcaccagc tgccgtacgc tgacccccgc gcagatcgag gccgtggggg agatggtgcg
    10381 tcagcggctt caggcccagc aggtgatcag ctcggggatc acactgtgag catcagaggt
    10441 gatctgagag tcggcgagac gcttcggggt tccttgagga agaagagtca ctcctacacc
    10501 gtcatggggc gagttgtcct gaaacggcgg gatcagcgaa gccggcgcct cactcggtgg
    10561 gagcagtggc gcctgatcga cgacaacagc gaagagctct ggctcgagat caatcgagat
    10621 accaatatgg ttgttcttca cgagccggtt cctattcagc cgatgatcga tccgctcgcg
    10681 ctcgaggtgg gccagaccct gcagctgaag gtcaatggtc gaccgtattc cgttgaggtc
    10741 aaggacgtat accgagccga tattgaccat gagacaggag ccgtcccaca tctgacagga
    10801 gctgttacaa caacgacatg cgttgagctc cgggtcaaag gggcgaggaa gcctctctcc
    10861 agcatcgtga tcgatgagca tcgccgccgg gagcgcgagg catatcgcat cacgaccctc
    10921 gcgcctgagc agcagtccaa gatcttcggt cggcacgtga gtcgaccgtg gtgggtgcca
    10981 ggcgttgcac gaaggctcgg ccggtggatc tcctcggtag gccctggact tcggggtggt
    11041 tggaagtcac ctctattctg gctcattccg tttctcattc tgatggcgat ccttgcgtgg
    11101 actgatgatg acgatttcag tcctgcggag gacggctccg tcttccggaa ccgctcggtc
    11161 tacggcggtg ggggcggcgg cgtcggaaaa taacctggag cccactgact caaccccctc
    11221 gacggtcata cacgaaggag aagacatgtc gctcatgacc atcgctcacc actcatcggt
    11281 cgacctcaac tggcagtcac tgctgagcac catcgtctac gcggtgctcg gagtggtcct
    11341 gctcatggtg ttcgcgctgc tggtcaaccg catcttccgt ctcgacctca gacgcgagct
    11401 catcgaggac cagaacatcg gcctgggggt tgccttcgcc ggcacggcgc tcgcgatcgc
    11461 catcatcatc gccgccacca tcctgagctg agccgcacac catgacccac ggtcgaatcg
    11521 ggcgacgaga gaacgtcgcc ctgttcactg cggccttgct cgccgcgatc ggcgggctca
    11581 tctacgagct catcctgggc acggccgcct cctacctcct gggcgactcc gtcctcagct
    11641 tcagtctcgc caccggcatc accctgttcg gcatgggaat cggctcgctg ctggtcaacc
    11701 gcttccgcgc cgcgccagcg gtcgtcttcg gagtcagcga ggtgcttctg ggcctcatcg
    11761 gcggcaactc cgtcctcctg ctgtacctgg ccttcggacg cacccgcctg cactgggtcg
    11821 tcttcggcgg catcagcctg accatcggca tcctcatcgg cctggagatc ccgctgctgg
    11881 tgcggacctt cgccgccttc gggcgccgct cgaccagtga gctgctcggc aaggtcatgg
    11941 ccatcgacta cttcggctca ctggtggcct ccctggtctt ccccctggtg ctcctcccac
    12001 agctgggcct catgcgcggg gcctacctgg tcggggcgct caacgtcctg gtcgcggtgc
    12061 tcgtcctgct ccaggtgcgc acacctcgca agatcctgtg ggcggccacc gccgccgtcg
    12121 tggcactggt cggtatgttc gcggccgcca accgcatcga gcgcagcgtg gaggcgctca
    12181 cctacaacga cccggtcgtc tactaccagc agaccgccta ccagaaggtg gtcctcaccg
    12241 actaccagga cgacctgcgc atgtacctca acggacagct ccagttctcc agcctggacg
    12301 aggccaggta ccacgagacc ctgtccgcca gcgccatgac ctcggtgaag gatcctgctc
    12361 acgtcctcgt gctcggtggc ggtgacggtc tgctggccag ggagatcctg cgctacccca
    12421 gcgtcaagga cgtcaccatc gtggatatcg accccggcgt caccgagctg gcgcgaagca
    12481 accgcctgct caaggacctc aacaaggcat ccctgtccga ccccagagtg aacgttgtca
    12541 acgacgacgc cttcacctac gtccgagact ccagggcgac ctacgacgtc gttctcgtcg
    12601 acctggtcga cccctccaac gagaagctcg ccaagctcta ctccaccgag ttctatcgga
    12661 atgtcgaggc tcggctggca cccgagggtg tcatggtcac ccaggccacc tccacgttct
    12721 tctcacccca cgccttctcc acagtggcca gcaccgttgc cacctcccaa ccggatcggc
    12781 agatcctgcc cttctcgacc aacattccct ccttcgggga gtggggcttc gtgctgtcca
    12841 ccaggacgcc tcagaacctc atcagccagc cgcttcccga gggactgacc taccaggacc
    12901 gggagaccct ggagttcatc atgcgaacca aaccggcccg caccgagacc atggagccct
    12961 ccactctcct gcatccgcgg atcgtcgagg tctacaaccg agacatgcgg cagtggcgct
    13021 actactgaac cacccaggaa gaggcggcga agtcggttcg gtctgaaaag ctccggaggc
    13081 gacctcgccg ctgtgccgtt accgcaccga gtaggccgcc ttacctcatc tcaggattct
    13141 gatggtcagc cagaccgcga tcccggcgat caccacacag ctcatcaggg acacgatgac
    13201 cgccatgccg aggatgagca gatagagcat cgacgccagc gttgccagcc agatgagcgc
    13261 gacacgagca gcgcgaggaa gtgctgtcgc caggcaggcc ccggctgcga cggtcaccag
    13321 cccgctgact gcgaagctca tgaagtcggg gtcagtgacg ttgacggact tgagcgtccc
    13381 tccccagatg atgatgagga gaccgcagac ggccaggcac gccccggcga tgtttcgtcc
    13441 gctcagccgc agccggggcg acttgtcgtg gttcgttgct gtcatgttgc tgatttcctt
    13501 ccgatgatgc gatgcgtagt tgtcgccaag gccctgtcgt tatctggtgt tcgccgaagc
    13561 cacgagctcg cgtccccagc tgtgggcgtc ggtcttctct ccatcggcca gcggaccctt
    13621 gctcgccgtg accacgaagc tcctgaccga caccgtccgc cgaccctgat ggcgctgcag
    13681 cgccttggcg atcgccttgg ccgctgaacc gctgagccag cccttggaga tgaccgtgtc
    13741 gaaggcggcg gcgccggtgg atgccgggat cgccgtggtc tccagccacc cgccgatccc
    13801 gtgggatgcc tcgcccgacc ccgcctgctc acaggccttg gcccgcgagg tcgcagtcgg
    13861 cagcccccgg ttgtgggtgg gggctcccag cacgagcaga tccaggtctg cgggcagggc
    13921 actcggagcc tgggaaacgt cgacgacctg tgcgtcgacg ctgccctcga tcagcccggc
    13981 ggcgacggcc tcggcgatgg cccgggtatt gccgaagtag gactcaacaa cgatgagtgc
    14041 cttggtcatg gtgtcctcct gaaggccggt accggcgatg tcgccggtga cgtgtgcgtc
    14101 atgaacccac tgtcaggtgt gacgccacgt cgcacgcaaa cggggcccgc cgctcagaag
    14161 gcgacgggcc cgtcagaccg aggagatcgg tgggtagggg agacgagtga gagcgacgaa
    14221 cgacgtcgcc gcgtccgcct cagagcttgg aggcgtcgac ggcgaaggtg ttgcaggcct
    14281 gtaccgagcc ggagttcatc ccggtggtga accagcgaac gcgctgctcg gaggagccgt
    14341 gggtccaggt gtcggagtcg acgtgtccct tcgcccgctc ctggatgtgg tcgtcaccga
    14401 cggcctcggc cgcccccagg gcaccgctga tctcctcgct gctgggacgg ctgaggaagg
    14461 gcttgccggt ctccgggtcg ggggtggagg aggcatggtt gacccagatt cccgcgtagc
    14521 agtccgcctg aagctccagg cgcaccgagt ccgacgtcgc gccactgccc gagcggtcgg
    14581 ccttggccat ctgcccggtc aggtgctgga tatggtgccc gaactcatgg gccacgatgt
    14641 actcctccgc caaaggagtg tccgtggccc ccagggactt ctccatctcg gagaagaagc
    14701 tcatgtccag gtagaccgtc tggtcccctg agcagtagaa gggccccacc gccgaggagg
    14761 cgttgccgca ggccgaggag atctgggtgc cgtcccacag gacgaactcg ggcttggcgt
    14821 acttgagccc cgcctgggcg ggcagctgat ccgtccacac cgcgtcgagg gactcggcgg
    14881 tggccaccat gcggcactgg gtgtacttgt tggcgctgtc cccgctggtg cacacggagg
    14941 tatcgatcga cgaggccgtc ggccgcgtgg ccccattctg ctgctgcgcc cccagcatgg
    15001 aggacaggtc cacccccgtg agctgggaga tgaggacgac ggcgatgacg gtcaggatcg
    15061 agccgccgcc gatcatcgct ccccggcctc cgccggaacg ggtctggacc cggttgggat
    15121 cgatctggat atcgcggttg aaggacacgg accacctctc agagcacgcc tgcgaccagg
    15181 ctggaactgc ccccacgcta ccgtgatacc gcccccgacg cgaagcaagg accaccaggg
    15241 gcgggactgc tcggaccgag cgcggttgcg gagccgtgcc aaccgtgccg gggtagcctg
    15301 gcaccgtgct ctacgacctg ctgtacaaga ccgtcctgac ccgcatcgac cccgagctga
    15361 tccacgacgt atgcatggac gccatcgagc tgactggcaa ggtccccttc atcagggacg
    15421 tggtgcgcca ggtgtgcggg cgccgccccg tcttccccgt cccctcggcc aaccagggcg
    15481 gtcccttcgc ccgccccgtt cccggtgtcc tggggctggc agccggtatg gacaaagagg
    15541 gacaggccgt cgagggcctg gacatgctcg gcttcggctt catcgaggtc gggaccttca
    15601 ccgcccgtgc ccaaggcggt aacgacaagc cccgtatgtg gcgctacccg cagatgcgcg
    15661 ccgtgcgcaa ccgcatgggc ttcaacaact ccggagcgga cgaggccgcc aagcggctgc
    15721 gcgctctgcg ccgcaccccg cggggacgct ccatcgtcgt cggcgcgaat atcggcaaga
    15781 ccaaggtgac gccccttgag gacgcggttg aggactaccg ctactcggcc aaggcggtgg
    15841 cccggtgggt cgactacctc gtcgtcaacg tctccagccc caacaccccc gggctgcgca
    15901 gcctgcagag cgtcgaggcg ctgcgcccga tcctcgaggc cgtgcgtgag gccgcggacc
    15961 aggccgccat gcgccacgtc ccactcctgg tcaagatcgc cccggacctt gccgatgagg
    16021 atctcgacgc cgtcgccgac ctggtcctgg acctggggct ggacggggtc gtggccacca
    16081 acaccaccat tgaccacgac ctgggtgacg gcggtctgtc cggagcgcct cttctgcccc
    16141 gctccctgga ggtcgtgcgc cgcctgcgca gccggctggg ggaggggccc accattattg
    16201 gcgttggcgg tatctcctcc atcatggacg ccgagctcat gctcgatgcc ggagcggacc
    16261 tgctccaggc ctacacggcc ttcatctaca acggtcccgc ctggccgggg cggatcaacc
    16321 gcgccctggc caccgcgtcg gccggttccg cagttcgtgc actgcgctga tccccgcccc
    16381 gtcaggcggg gcgcttctcg ggggaggagg tcagtgacgg gtcccgctca acgacgtcgc
    16441 ccagggcgat gtcgatggcg gccatgacgt cgtcgtccag gtgcacgcct gaggccctga
    16501 ccgtgtccgc cagctgctcg gggcgcgagg cgcccacgat cgccgaggag acggccgggt
    16561 tgcgcaggac ccaggcgatc gccagctgcg gcatggtcag cccgaggtcc tgggcgatcg
    16621 ggcgcagggc ctggaccgcg gtgagtacgt cgtcgcgcat ccaccgcgag atcatctgcc
    16681 ggccgccctt gtcatcagtg gcccgtgagc cggcgggcgg ctcctggccg ggcaggtact
    16741 tgccggacag gaccccctgg gccattggcg accacacgat ctgtcccagc cccagatcct
    16801 ggctggtggg caccaccctg tcctcgatga cccgccacag ggccgagtac tggggctggt
    16861 tggacaccag acggaaaccc atctgcgtgg ccagctcctg gccggcacgg atctgctcgg
    16921 ccgtccattc cgagaccccg atgtagaggg cctttcccgc ccgcacgacg tcggcgaagg
    16981 cctgcatggt ctcctccagc ggcgtctcgt ggtcgtagcg atgggcctgg tagaggtcca
    17041 cgtagtccat gcccaggcgc gtgagggaac cgttgatgcc ctccatgatg tgcttgcgcg
    17101 acagacccac gtcattgggg cccttggggc cgatgggcca gtagaccttg gtgaagactt
    17161 ccagggactc gcggcgccga ccggccagcg cgcgccccag aacctcctcg gcgaccgtgt
    17221 tggcgtagac atcggcggtg tcgaagctcg tgattcccag gtcgagggcc gtgtgaacgc
    17281 attcgatggc cgtacccgcc tccacctggg agccgtgggt gagccagttg ccgtaagtga
    17341 tctcggtgat cttcaacccg gatgaaccca ggtgcctgta tccaactgtg tgttccataa
    17401 caccacccta cggtacggtc ccacgacgtg gaaccgtcgc gggaccgggg cgggtcggac
    17461 gagcgcgggt tcaggagggg tactggcccc gtttcaccag ggtggccgga cggcgccagc
    17521 gccgcagcat gaagcagcgc gacatgatgt agaagaagat cattccctcg ttcttgaccc
    17581 gctcctcccc gaacttcttg tgaagacggc ggcgcagccg gttccagcac cagacggcgt
    17641 cgacgatcgc gagcagcagg tagccgttca tcgccagcac ggcgtagaag ctgatcaccg
    17701 ggtactgggg caggatgtgg ttgaacccga aggagaggat gagcaggacg aagatgaggg
    17761 gcatgaagaa ctcgcccagg ctgaagcgcg cgtcgacgta gtcgcggatg taacgcttga
    17821 ccggcccctt ctcccgggat gggagatact tctcgtcacc ggtcaccatg gcctcactct
    17881 gccgcttcca ggcctcgtcg cgggccgctc gcgcctctcg cttggcggcc ttgcggtcct
    17941 tgggaaccac ggggtgcaga ttcttggcct gctggtccct gcgcttggga gtggggcgcc
    18001 ctttgccaac gggcttgggg gcgggctcgg ctgcaggctc cggctcgggg gtctggctgc
    18061 gcttcttgaa caggctcacg gtgcacagac taacggcagc ggcacgatac cctgaaaacc
    18121 atgatcaccg ttgatgccgt gcgcaacgct gtgcacacct ccatgcccgc catcgtctcg
    18181 gacctgaccg atctggtcac gatcccctcg gtctccgcct ccagccacga ccagtcccag
    18241 gtccggcgct ccgccgaggc cgtggcctcg ctcctgcgcg acagcggtct ggacgccgag
    18301 atcctctctg tgcccgcccc ggacggcgcc cccggcaggc ccgccgtcct ggcccacaag
    18361 gcgggccccc agggcagccc gcacgtcctg ctctactccc accacgacgt ccagcccgtc
    18421 ggtgacccga ccggatggga ccaggccgat cccttcaccg ccgagcggcg cggtgagcga
    18481 ctcttcggtc gcgggaccgc cgacgacaag gccggtgtca tcacccacgc ccacgccctg
    18541 cggaccctgg cctccctggc ggacggcgag ctgccctgct cggtgacggt cttcatcgag
    18601 ggggaggagg aggtcggcag cccctccttc gagagcttcc tgaccaccta ccgtgaccgg
    18661 ctcgcctccg acgtcatcgt cgtggccgac tcctccaact ggaaggtcgg cacgccgtcc
    18721 ctgaccaccc tgctgcgcgg cgtcgtccag gtcgatgtcc gcctcgacat gctcgatcac
    18781 gcgcttcact ccggccagta cggcggcccg gtcctggacg ctgccaccgc catgtgccgt
    18841 ctgatcgcct cctgccacga cgaggccggt gacgtcgcca tcgccgggct ggtcagccgg
    18901 cctcaggccg atgccgactt cccggactac ccggaggccg acttccgcgc tgacgcaggg
    18961 gtcctcgacg gcgtcgagct ggtcggcacc ggtgatctca ccgcacggct gtggaccaag
    19021 ccctccctga ctctcatcgg tatggacgtc accccgctgg acctggccgg caacgtcctg
    19081 accccctcgt gcaccgcccg cctctcgctg cgcatcgcgc cggggcagga ccccgccgag
    19141 gcgcaggcgg cactggtcgc ccatctggag aagcacgtgc ccttcggcgg ccggctgacc
    19201 gtcgagggcc gcgaggccgg tccggccttc gacggctccg agaccacccc cgcctccgag
    19261 gctgcccgct gggcgctgtc caccgcctgg agcaccgagg ccgtcaacat cggccagggc
    19321 ggttccatcc ccttcatcgc cactctcaag gagaccttcc ccgaggccca ggtgctcgtc
    19381 accggtatcg aggaccccga cacccgcgcc cacagtgaga acgagtccat gcacctgggc
    19441 gagctcgagc acatcgtcgt cgcagaggcc ctcctgctgg cccgactcgg cgacgccatc
    19501 gcctcatgac gtctcccgta cgccggcact gctccctccg ggccgcggta tgagggtcct
    19561 cctcgctcct gggggcttat ggcccgagcc ggccggagtg ccgctggccg gactcggccg
    19621 cggtcttccg gccggccgcg tcgccgcctg cctggcgcgc ggctggcagg cggcacgtcc
    19681 cagtgacgct ctgaccctga tgcccatgtc cgacggcggc ccgggatcgt cccaggccat
    19741 cgctccggag cgcatcgcct cccgtgaggt catccaggca cagggaccgc tcggacaggt
    19801 ccgcgaggtg gatctggtga ggatggctcc cagtccctca aaccctggcg gtcggcgccc
    19861 cggcgagggc gggacctggt tcctcgacgc cgcccgcctg ctggcggtcc cccccgaccc
    19921 cgataaggcc gcccaggaag cgcttcgggg aagcagccat ggcctgggtc aggtcatagg
    19981 cgtcgccgtg gaccgtatgg ctccttccga caccctcctg gtcggcctgt cacgcgctgc
    20041 cgtccacgac ggcggggccg gagtcctgga cgccctcggg ggcgcttctg cggccgcgga
    20101 gctgcttgcc gggcgcagca tcggactggt cctggctgac gacatcgccc tgggaggact
    20161 gagcggggcg ggcgcggctt tgaccaggat cgccgccttg agcccccggc aggctcagga
    20221 gctggaccgc cgcgcctgcg ccgcagccgc tgaggccgtg agcacagccg aagccggcgc
    20281 accgcaggtc tcctcgaggg ggcagagaat gctccccgtc atctcggcgc tcgatgaggc
    20341 ggcgctgcct tcgtctgcca ccgcggacct cggtggaccg cctcgtctga gtgcctcgac
    20401 ctgggggacc ggcgcggccg ggggcagtgc catggtgctg cgcgccctgg gggcctgggc
    20461 acggcccggg gcccgtgtca tggcggagat actcggcctc tccgaggcgg tgtcaggcca
    20521 ggacctggtg gtcaccgcct cgggtgagct ctacgacgtt ccggccgacg gggtcgtagg
    20581 cgtcgtcggc caccatgccg cctcccaggc gctgccggtt gccatggtgt gcgggcgctg
    20641 cgtcaccacc cgcggtgagc tcgccggcgc cggtatctcc aacgcgtaca gcctgcagga
    20701 gccccatgcc gctgagtcgt gggacgccgt cggttccgac gcgcttcagg accgcttgac
    20761 ggatatgggt gcccggttgg cccgcacgtg gtcgcgctga gccggacgga acgcggtgct
    20821 ccctgaacca gcattgacca gcatggacca gcgctgacca gcgccgccca gcgcgctgcg
    20881 gcggagtgcg cctacggctc agtcgatgaa agccgcggcc gtcgagtcgc gcacgatgag
    20941 gtcgggggcg aagagcatct cggtgtcggt tggccgctct ccgtcgagct gggccagcag
    21001 cgtggacacg gccgcccggc agatagagcc cacgggctga cgcaccgtgg tcagcggtgg
    21061 gtcggtcatg ggaatgagcg gtgagtcgtc gtagccgatg acggagacgc gtgcggcacg
    21121 gatctgccgg tctgacgcac cccgtggacg actccgaggg ccatgacgtc cgaggagcac
    21181 acgatgccgg tacacccctg ctcgagcagg tgcagtgcag cgctgatacc gccctcgtag
    21241 gtgtagagcg tctcaacgat ccgcaggggc tcctggggca ggccctccct catggcgtcc
    21301 tcgtagccgg accgcttgcg ctgagccggg accatgcgca tcggccccat ggccagcccg
    21361 atgcgttggt gtcccagggc aatgagatgg tccacagcca tccgggtcgc ccggcggtca
    21421 tcggtcgcga agcccggggc cttgatggtc ggtgcgttgc cgttgaccgt caccagtgga
    21481 acgccgcgct cacgcagacg ctggtagcgg gtgacgtcgc cggtggtgtc cgcgtggcgc
    21541 ccggagacga agatgatccc tgcgacgccc cggtccacca gcatctcgat gtactcgtcc
    21601 tcgctgatgc caccgggtgt ctgggtgcac agcagcgggg tgtgtccgga aggggccagg
    21661 agctgctcga tctgctgggc gaacaaggga aagatcggat tgctcagctc cggcacgatc
    21721 agtcccatga ggccccgcga cgactggtgc acggactcgg gtcgctcgta gccgaggatg
    21781 tcgagtgccg cgagcacctg ccgccgagtc gagtcggcca cgttggactt tccgttgagc
    21841 acacgcgaga cggtggcggt ggacacgcct gcctggtcag cgatgtcggt gagagtgagt
    21901 ctctgcggca taagtgaatc ctacgaggat cggtgaaggt ctaggggcca cttcgcgtga
    21961 acagacggtg gttcgtcgtc cggccctcca gccgcaatcc tcgcagatca ggggctgttc
    22021 tcgtgaatca agggcggcga caaggcgcct cacgcctctg attcacgctg ctgggacggg
    22081 gcaggagagg tggagcggtg tagcccacgt tcagcccttg actgcgccgg agatcgagcc
    22141 accgacgatg tagcgttgga ggtactggaa cagtgcgatc accggagcca tggtgagaac
    22201 cgcaccagcg gcgaagatcc ccaggttgtt ggagcggtca ccgacgagca tgccgtagag
    22261 ccccaccgcc agggtcttct gggagttgtc ggtcaggatg atcgacccca ggaggaactc
    22321 actgatgaca ccgacgaagg ccagtaggaa ggtcgtggcg atgatcggtt tgagtgtggg
    22381 cagcaggatg attctgaaga cctgccagtg ggtgcagccg tcgatgatgg cggcctcatc
    22441 gagctcacgg gggatggtgt cgaaggttcc cttgatgagc cacacctgac ccagggcccc
    22501 acccatgagc gccaggctgt agccggcgag cgtgttcaga ccaagggagg ggacgacctg
    22561 gccgatgtcg gagatcatcg tgtagatggc gatcatggac aggatcgccg ggaacatcat
    22621 gatcaggagc agggccagca gacctccgcg acgtccggtg aaacggaagc gggagaaggc
    22681 gtaggccccg agcagggaga gaaatacctg ggcggtagcc actaccgagc agatgatgat
    22741 ggtgttgagg taccagcgca ggaaggggcc gcgcgctccc gccagcaggt tctggtagtt
    22801 gaccagactt accttggtgg ggatgaggcc ggtggaggcc accgttccca gcgggttgag
    22861 ggaggcggag atgacgtaga ggacggggaa ggcggcgaag acaagggcga cgacgccgac
    22921 aacgtgcctc catccgatct cacggaacca tcgggagaac ggcatgtggt tctctgccgg
    22981 caggacgttc tcggagcttt tggacacggt tttggaagag gtgctcat
//
