LOCUS       NZ_CP092466.1          21929 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP092466.1 Citrobacter portucalensis strain Cf7303 chromosome,
            complete genome.
ACCESSION   NZ_CP092466
VERSION     NZ_CP092466.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:16:25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4375951
            Orig. end    :: 4397880
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21929
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[4385951:4387880]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..11929
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..21929
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21929
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="22"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             507..1322
                     /locus_tag="ctg1_4159"
                     /transl_table=11
                     /translation="VTHTRDIPQSFWRDEQLPWLELRSTWQSQQAYKRHHHSQLSIGAI
                     LEGETCCLCDGEEYHLQVGDLIVIPPLAPHSCNPVNGQFRSYHMLYLDAKWCLANLPAQ
                     NTNQRLCTPAPVIRDAQLFQRYMHLVTLMPQRQTAQITDAAQTLLHSLPLQSVTPENLS
                     ATSQYLRERLQSSLLAPPSLDELAHECHMRKETLIRTFKQDTGLTPGSYLNIIRIDYAR
                     QRLRAGDEIADVGYQSGFADQSHFHRTFVRYTAATPRQYALGRSISDNN"
     CDS             1371..2021
                     /locus_tag="ctg1_4160"
                     /transl_table=11
                     /translation="MSLLSVLFPSAFPALALAHFVALLSPGPDFFLLVGYAARYRMRGS
                     AGLCVGIAFGNGLYILLAIIGWGILRQLPLLFTVIELLGALYLLWIGSLLVRSRPQTLT
                     GTDAQSTCPGFGKQILLGLGSSLLNPKNALFYLALMTALLGPSVTLLQQTMSGIWMTSI
                     VLCWDLLIVMFIGLPQIQRRLSRGILWVERIAGGVLIIFGCAIALRFLQSIVV"
     CDS             2347..3588
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 111; E-value: 2e-34)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4161"
                     /sec_met_domain="MFS_1 (E-value: 1.6e-32, bitscore: 111.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRILAFFSQRATTLFFPVALILYDFAAYLSTDLIQPGIINVVRD
                     FNADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLFTTSM
                     TQFLAARFVQGTSICFIATVGYVTVQEAFGQTKAIKLMAVITSIVLVAPVIGPLSGAAL
                     MHFVHWKILFAIIAVMGLIALIGLTLAMPETVQRGAVPFSARSVVRDFRDVFRNRVFLF
                     GAATLSLSYIPMMSWVAVSPVILIDAGGMTTSEFAWAQAPVFGAVIVANMVVVRFVKDP
                     TRPRFIWRAVPIQLSGLAVLIAGNLLWPHVWLWSVLGTSLYAFGIGMIFPTLFRFTLFS
                     NNLPKGTVSASLNMVILTVMAVSVEIGRWLWFNGGRISFHLLAVVAGIAVVFTLAGLLK
                     RVRQHEATALVTES"
     CDS             complement(3673..4233)
                     /locus_tag="ctg1_4162"
                     /transl_table=11
                     /translation="MKLKDLFSRTPTERRHYGVAVLVGIISGVLSAFVKWGAEVPLPPR
                     TFSLGRNEFNPPYLFLRDYLGIDPTQTVYTFSEHVINPVMVTHIIFSLVFAVGYCVAAE
                     IFPKVKLWQGVLAGLIVTVAVHGIFIPALHLSPPLSQLPFDEYVSEIIGHIFWFWVIEM
                     IRRDLRNRITHEPDAEVPLSLVR"
     CDS             complement(4472..5662)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4163"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 1.2e-113,
                     bitscore: 377.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDAMKLETHLVVAGRDKRYTQGAVNPVIQRASSLVFDTVKDKKF
                     ATANRANGELFYGRRGTYTHFAFQKAMSELEGGVGCALYPCGAAAVTNAILAFVQGGDH
                     ILMTGAAYEPTQDFCNKILSKFNVETTYYDPLIGAGIVDLLRPETKVVFLESPSSITME
                     VQDVPGMVKAIRAVNPEIVIMIDNTWAAGVLFKALDYGVDISIQAGTKYTIGHSDAMLG
                     TAVSNARCWDRLRENSYLMGQTLDADTAYNGSRGLRTLAVRLKQHQESSIHIARWLSAR
                     PEVARVNHPALPECPGHEYFQRDFIGSSGLFSFVLKKRLTDEQMANFLDNFSLFHMAYS
                     WGGFESLILANQPEELNSIRPAGEVDFSGTLVRVHIGLEDIDDLIADLEAGFARIA"
     CDS             complement(5693..6925)
                     /locus_tag="ctg1_4164"
                     /transl_table=11
                     /translation="MWSRLEPYRSSIILLVALVIGGLLGIYAPSFASKLQPIGQIFLNL
                     LFMIIVPLVGISVMSSIASMTDLKRLGRIMAIIFIVSIAMAFIPAAGIVALALWYNPAQ
                     GVTIDLSQSVQAGSGKMDFVSMITTSDFIGLFSKSNILALIVMAIIAGVAIGQSDQAGK
                     RIASLLEDANTVIMKIVSIIMKVAPIGLGCYFAATMASQDSALLLTFARAIGLFMVATL
                     VYFVFGSILYSYIGGGIPAVKAFWRNAIEPSATALGTCSSLGTLPVTLRAGKAMGINPE
                     IVDVSIPLLVNLNKGGVAMIAALKIVFIYSVLGMEFTTETFFLTMLIAVLSAIIVGGVP
                     GGAFLGEIFIVTTLGLPMEAIPMLVVLGTITDAPATLINVIHDLNAAQIVERFAGKKQT
                     NAEINSTAAVV"
     CDS             7145..8071
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     68.7; E-value: 1e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4165"
                     /sec_met_domain="LysR_substrate (E-value: 7.3e-33,
                     bitscore: 111.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.1e-20, bitscore: 68.7,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPISLKHLEFFTKIVDCGGLSEAAAQLNVSPSAVSKSLAAMED
                     TLGTTLIKRTTRSITLTDAGQYLFNRANKLLKEFDETLNTTSGYYHSPQGELRITCSIA
                     FGYSRLVNLVDKYRSQFPDVNLYIDLNDNFVNLNETDFDIALRISTAPPQNYAMRKLVP
                     VRWAYCASPGYLAKKGMPQRRSDLVDHDCLVYPGLTPVLKVADEQDRLHQLKLHMPIQA
                     NSSLVLLKSVLEDQGVAYLPTYLIGDHIQKEEITPLMLDGTITCETHALYALYFPSKYS
                     NPKVRSFIDFLVAELGPLPAWDNWIPE"
     CDS             8147..9427
                     /locus_tag="ctg1_4166"
                     /transl_table=11
                     /translation="MNKIAELKRAKRLALSLLLIAAATFVITLFLPPNFWVLGIKAIAE
                     AAMVGALADWFAVVALFRRVPIPFISQHTAIIPRNKDRIGENLGQFVQEKFLDTQSLVA
                     LIRRHEPALLIGNWFSQPENAQRIGQHLLQIMSGFLELTDDSRIQRLIKRAVHKAIDKV
                     DLSGTSALMLESMTKNNRHQVLLDTLIAQLIALLQRDSSRAFIARQVVHWLETEHPLKA
                     KILPTEWLGEHSAELVSDAVNSLLDDISHDRAHQIRHAFDRATFKLIDKLKHDPEMAMR
                     AESLKSYLKEDEAFNRYLGELWADLRQWVKTDINADDSRVKQRIASAGQWFGETLVADS
                     ALRASLNGHLEQAAHKVAPEFATFLTRHISDTVKSWDARDMSQQIELNIGKDLQFIRVN
                     GTLVGGSIGLVLYLLSQIPSLLTLANF"
     CDS             9441..9905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4167"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.1e-14,
                     bitscore: 51.0, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMNIRIFSLRETPEKLHEVTAYFQQQWASEDSVKVYEDALHRCI
                     GAKNPLPQWYWLQDGDSIVGCAGLITNDFISRGELWPWLCALYVDPRYRGHGLAFRLIE
                     HIAQQAKQLGFMQLHLCTDLEGLYEKAGFYFDGPGYHPWGEVSRVYSRNL"
     CDS             10001..11152
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4168"
                     /sec_met_domain="HGD-D (E-value: 5.1e-83, bitscore: 277.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLITDLPAIFNQFSDARQKGFLTVMDLKEQGIPLVGTYCTFMPQ
                     EIAMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLVVG
                     ETTCDGKKKMYEYMAEFKAVHVMQLPNSASDAASRALWKAEILRLQQAIEARFGTPITE
                     AALREAVILKNQERRALANFYRVGQLNPPALSGSDILKVVYGATFRFDKEALIDELNSM
                     AERVHQKWQAGKRLASRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGAKATEQ
                     CVEETGDVYDALTDKYLAIGCSCISPNDQRLQMLSQMVEEYQADGVVDVILQACHTYAV
                     ESLAIKRHVRQQHNIPYIAIETDYSSSDIGQLSTRVAAFIEML"
     CDS             11162..11929
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4169"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.8e-65, bitscore:
                     219.3, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYSIGIDSGSTATKGILLERNVIRRRFLCPTPFRPAEAIAQAWE
                     TLQAGLDDRPFLTLTGYGRQLVDYADKQVTEISCHGLGARLLAPGTRTVIDIGGQDSKV
                     IQLDDDGNLSDFLMNDKCAAGTGRFLEVISRTLGASVEQLDAITAGVEPHAITSMCTVF
                     AESEVISLRSAGVAPEAILAGVINAMARRSANFIGRLSGQAPLLFTGGVSHCHAFARML
                     EGHVGIPVHTHPDAQFAGAIGAALIGQRQGKRK"
     CDS             11926..12177
                     /locus_tag="ctg1_4170"
                     /transl_table=11
                     /translation="VKEALFLFHSTLGVIKTRKALQAAGMCFRVADIPRELRGGCGLCI
                     YIDCVAGKEDEWIIPGHTESIYRLENGGWRCLATFPPS"
     CDS             12272..13459
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 55.9; E-value: 1.1e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4171"
                     /sec_met_domain="MFS_1 (E-value: 8.5e-16, bitscore: 55.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQGSPDSNRHAISVALFGMLVLTLGMGIGRFLYTPMLPVLLSEG
                     QFTFEQLSWIASANYAGYLAGSLLFSFGLFHLPSRLRPMLLTSALATAGLILAMASLTQ
                     PALVMLIRFLAGVASAGMMIFGSMIVLHHTRHPFVIAALFSGVGAGILLGNEYVISGLH
                     FALSSHTLWLGAAAASALFFVLLVILLPSRNHVLPAAAPVKTEHQPISWWLLALLYGLA
                     GFGYIIVATYLPLMAKSAGSPLLTAHLWSLVGISIIPGCFAWLWAARRWGVLQCLTANL
                     LIQSACVVMTLASGSLPLLVISSMGFGATFMGTTSLVMPLARQLSVPRNINLLGLVTLT
                     YGIGQILGPLLTSLLGSGAQAIVNATVCGAVALFIAALISLTQLYKQRFASPKRV"
     CDS             13651..14052
                     /locus_tag="ctg1_4172"
                     /transl_table=11
                     /translation="MSWFKKILLGLIILAGLIGTLKDYKDFGLFGALGLFIIFLLSTTF
                     LWQWASGKLPEITKLHAILILLASAVASIFVINMAIAGNLHVDLMEVMRVTITHNPLFY
                     LILCVVAWVKVGIWQWLFSGVQMKESQPV"
     CDS             complement(14115..15122)
                     /locus_tag="ctg1_4173"
                     /transl_table=11
                     /translation="MKKSAVVLAVMALGVTSVHAAEIYNKDGNKLDLYGKVKAVHSWTD
                     GTDADGTYARLGFRGETQINDQLTGYGQFESQFDAAKAEGSQNGVNTRLAFAGLDYGHD
                     VSFDYGRNYGIAYDVGAYTDTLSEFGGDSYENTDRFLTTRTSGVATLRTKNLFGAVDGL
                     SLGAQYQGQDDSDKDPTKQHGNGYGFSLGYDNIADSGVSAIAAYTNSSVTAQQKQNGWD
                     GENAEFWGAGLKYDANAIYVATMYGESHNLIQDADKAQHFEAMAAYVFDFGLRPNVAYV
                     HARDNNNTDLTEYVALGTDYYFNKNMVADVGYKINLLDGKDGDNQVVAGLTYQF"
     CDS             complement(15310..15513)
                     /locus_tag="ctg1_4174"
                     /transl_table=11
                     /translation="MPSRDYPDIRKARGTRSKDMVLLSARVDTSLWEYVRMLAFETRKS
                     KQDIIAEALMLHRSINQSENQE"
     CDS             complement(16148..16873)
                     /locus_tag="ctg1_4175"
                     /transl_table=11
                     /translation="MIRDLIVQTPYQPGERLPPEREIAERLNVTRTVVREALIMLEIKG
                     LVDVRRGAGIYVLDNADAQTIDSSDVNHCNDAGPFELLQARQLLESNIAEFAALQATRE
                     DIVKMRQALQLEERELASSEPNGSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNP
                     MWIQLHSHLDDTHYRKEWMGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVD
                     DIDFDGYLFDSWPLDKVNA"
     CDS             complement(17097..18572)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4176"
                     /sec_met_domain="Mannitol_dh (E-value: 1.4e-51, bitscore:
                     172.8, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Mannitol_dh_C (E-value: 5.3e-98, bitscore:
                     325.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTIANSNLPVARPAWDSSRLQSRIVHLGCGAFHRAHQALYTHH
                     LLETTDSDWGICEVNLMPGNDCILIENLRKQQLLYTVAEKGADNTVLKVIGSMKEALHP
                     ELDGCDGILQAMARPQTAIVSLTVTEKGYCTDAASGQLDLNNPLIKHDLANPAAPKSAI
                     GYIVQALHLRREQGLAAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAQWIEANATFP
                     CTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQF
                     VADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPAYRKAAFALMMQEQAPTL
                     SMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGSGWRH
                     LALGIAGWMRYTHGVDEQGQVIDVVDPMQAEFQRINQQFQGAERVTALLGLSGIFGHDL
                     AENTDFVATVTAAYQQLCEHGARECVAALSADE"
     CDS             complement(18653..19837)
                     /locus_tag="ctg1_4177"
                     /transl_table=11
                     /translation="MEQTWRWYGPNDPVTLADVRQAGATGVVTALHHIPNGEVWTVDEI
                     LKRKAIIEQAGLVWSVVESVPIHEDIKTRSGNYQQWIANYQQSLRNLAECGIRTVCYNF
                     MPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQANERFT
                     TMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLERYKDIDKAALRENFAVFLKAIIPV
                     AEEVGVRMAVHPDDPPRPILGLPRIVSTVEDMQWMVDTVNSMANGFTMCTGSYGVRADN
                     DLVDMIKQFGPRIYFTHLRSTLREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEQRRKAE
                     GKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVEMAIQRAFFSR"
     CDS             20099..21442
                     /locus_tag="ctg1_4178"
                     /transl_table=11
                     /translation="MHVLNILWVVFSIGLMLVLNLRFKINSMVALLLAALSVGMLAGMD
                     LMELLHTMKSGFGSTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQLSV
                     IIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQPGP
                     VALVNAYGADMGMVYIYGILVTIPSVICAGLILPKFLGNLDRPTPSFMKADVPVDQNNL
                     PSFGVSILVPLIPAIIMISTTIANIWLVKGTQAWEVVNFLGSSPIAMFIAMVVAFVLFG
                     TARGHDMQWVMNAFENAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSHGNISPY
                     IMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVDPALLVLATAAGSNTL
                     THINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMIA"
ORIGIN
        1 tgccatatgc gcatccggtg tgctttggtg ttcaatcacc acataaatat atccatcccc
       61 atccgtcgtt ttcaccgacc acagcacatc ggaatagtac gcacgtaaat tctcttcgat
      121 aaaactgtct gactcgagtt taagcgtctg aagatcgcaa agctcgcgca gcaaagcggg
      181 aagatgtatt tgcagaaaat cccgtgcagt ctcagggtga cgtaaaaatg ttttaaaaac
      241 cgcgtcatgc ggtgttgaag cggaagcttt gttcatggcg atccttcacc tgaaaataag
      301 atgccatgac tgtagcgccg gaaaaccaca tcctcccctg caactttctc tctttgcgag
      361 acgatttccg ggataacaac gcccttatgt aacgtctgca tttgtctgga acacgtcacg
      421 cagaatcgcc atctcaatgc gcattcccac tttttcacca ctcggcctgt gctataacaa
      481 atcatcactt tcagggagga cacgatgtga cgcatacccg agatattcca caatcgttct
      541 ggcgtgatga gcagttgccg tggctggaac tgcgcagcac ctggcaaagc cagcaggcct
      601 ataagcggca tcaccactct cagctctcga ttggggcaat tctcgagggg gaaacgtgct
      661 gtctgtgcga tggcgaggaa taccatctgc aggtgggcga tctgattgtg ataccgccgc
      721 tggcacctca cagctgtaat cctgttaacg gacagtttcg cagctatcat atgctttatc
      781 ttgatgccaa gtggtgtctt gctaatctgc ctgcacagaa caccaatcag cggctttgca
      841 cgcctgctcc cgttatccgc gatgcgcaat tattccagcg ttatatgcac cttgtgacgc
      901 ttatgccgca acgccaaacc gcacaaataa cggatgccgc gcaaacattg cttcactcgc
      961 tgccgttaca gtcggtcaca ccagaaaacc taagcgcaac cagccagtat ctgcgcgaac
     1021 ggttgcagtc cagcctgctc gcgccgccct cgctcgatga gctggcacat gaatgtcaca
     1081 tgcgtaaaga gacgctgatc cgtaccttta agcaggacac cgggctgacg ccaggaagtt
     1141 atctgaacat catacggatt gactatgctc gccagcggct gcgggccgga gacgaaattg
     1201 ccgatgtcgg ctaccagagc gggtttgccg accagagcca tttccatcgc acctttgttc
     1261 gctacaccgc cgccacaccg cgccagtacg cgttgggacg atcaatatca gacaataatt
     1321 agcgctgcgt caggcgtacg gtgatctcag attcattctc tgaggtcgct atgtcgctgc
     1381 tttcggtact ttttccttct gcttttcccg cgctggcgct ggcgcatttc gtcgcattgc
     1441 ttagccccgg gccggacttc tttttactgg tcggttacgc cgcacgatac cgaatgcgcg
     1501 gcagcgccgg gttgtgcgtg gggatcgctt tcggcaacgg gctgtatatt ctgctggcaa
     1561 ttatcggttg ggggatcctg cgccagcttc ccctgttgtt tacggttatt gagctgctgg
     1621 gcgcgctcta tttattgtgg attggcagcc tgctggtacg cagccgcccg caaacgctga
     1681 ccggaacaga cgcccagtct acctgtccag gatttggcaa acagatacta ctgggattgg
     1741 gttcgtcact gctcaaccca aaaaatgcgc tgttctatct ggcgctaatg accgccctgc
     1801 tcggcccgtc ggtgacgctg ctgcaacaaa ccatgagcgg gatctggatg accagcatag
     1861 tgctgtgctg ggatctgctg atcgtgatgt tcatcggttt accgcagatc cagcgacggt
     1921 tatccagagg gatattatgg gtagaacgta tcgctggcgg tgtattgatt atcttcggtt
     1981 gtgccatcgc tctgcggttt ttgcagagca tcgtagtctg atttgcaggg cgattttctg
     2041 cacataaacc ggataaactc gtttaattaa tatccaatcc gcattacact gcggatggtt
     2101 attacccgtt caacttactc ttcctgaggt gcgatgtgct gattgttacc tgtaatcgtt
     2161 acgttttctg accccgcgtc agtgagcgta tcttctgttt gcgcttcgcg cagacagcgt
     2221 ttttgattac atgaaattca gtacatttgc agtctgcttt ttttctgtca tcggtctgac
     2281 gtctcaaaga cggtattgaa tttcgctatt cccgttgagg gttttctccc gacaaggagc
     2341 tgttttatgc aacggattct cgcgtttttc tcccaacgcg ccacaacgct tttttttcct
     2401 gtcgcattga ttttatatga cttcgccgcc tatctgtcga cggacctaat ccagcccggc
     2461 atcattaatg tcgtacgcga tttcaacgcc gacgtcagcc tggcgcccgc ggcggtcagc
     2521 ctctatctgg cgggcggcat ggcgctgcaa tggctgctgg ggccgctttc cgaccgaatt
     2581 ggccgccgtc cggtactgat tgcgggagcg ctaattttta cgctcgcctg cgctgccaca
     2641 ttgttcacca cctcgatgac gcaatttctg gccgctcgtt ttgtgcaagg caccagcatc
     2701 tgttttatcg ccaccgtcgg ctatgtcacg gtgcaggagg catttgggca aacaaaggcc
     2761 atcaagctaa tggcggtaat cacctctatt gtgctggtgg caccggttat cggcccgctc
     2821 tccggagcgg cgctaatgca ctttgtacac tggaagatct tgtttgccat tatcgccgtc
     2881 atggggctta tcgcactcat tggactcaca ttagcaatgc cagaaaccgt ccagcgtggc
     2941 gcggtgccgt tcagtgcgcg cagcgtagtg cgtgattttc gcgacgtttt ccgcaaccgg
     3001 gtgttcctgt ttggcgcagc cacgctgtcg ttaagctata tcccgatgat gagctgggtg
     3061 gcggtctcac cggttattct gatcgatgct ggcggcatga ccacatcgga gtttgcctgg
     3121 gcacaggccc cggtatttgg cgcggtgatc gtcgccaata tggtggtcgt ccgcttcgtg
     3181 aaggatccga cccggccacg ctttatctgg cgagcggttc ccattcagtt gagcgggctg
     3241 gcggtattga ttgctggcaa tttactgtgg ccgcacgtgt ggttgtggtc agtgctgggg
     3301 accagcctgt atgcgtttgg cattggaatg atcttcccaa cgttattccg ctttacacta
     3361 ttttccaaca acttaccgaa gggtacggtt tcggcgtcat tgaatatggt gatcctgacg
     3421 gtgatggcgg tttctgtcga aattgggcgt tggttatggt tcaacggcgg caggatttcg
     3481 tttcatctgc tggcggtggt ggctggtatt gccgtcgtgt tcacgctggc aggcttacta
     3541 aagcgcgtac gtcagcatga ggccaccgca ttagtcacag agagttaacc tcctatgaac
     3601 cgcccccatt cgcgaacagt ggttttgtgt ttagcggtcg ggggcaatcc atcatagtgc
     3661 atcaactttt aatcatctga cgagagataa cggaacttcc gcatcgggtt catgcgtgat
     3721 ccgattacgc aggtcacgac gaatcatttc aatgacccaa aaccagaaaa tatgtccaat
     3781 aatttccgac acatattcat caaatggtag ctgagacaag ggcggcgaaa gatgaagggc
     3841 gggaatgaag atgccatgaa ctgccaccgt cacgattaaa cctgccagta ccccctgcca
     3901 aagtttaact tttggaaaaa tttcagcggc aacgcaatat ccgactgcaa acactaatga
     3961 aaatatgatg tgcgtgacca taaccggatt aatcacatgt tcagaaaagg tatagaccgt
     4021 ttgcgtgggg tcaatcccta aatagtctcg gagaaaaagg tacggaggat taaactcatt
     4081 tcttcccaga gaaaatgtcc tgggtggaag cggaacttcg gctccccact taacaaatgc
     4141 agaaagtacg ccagaaatga taccgactag cacggcaaca ccataatggc ggcgttccgt
     4201 cggtgtcctt gagaataaat ctttcagctt cataactcat catcccttat atgccataac
     4261 acttaaaacc agtggctatg ctacccagga gggatgctga aaattgtgac aaagattact
     4321 tttgataaaa aatgatctta aatgactact tatgagttaa tttgattgtg aatatagctt
     4381 catcgcgaat gtcgtacagg cgttttatcc ggcctactgg gttacgtagg ccggataagc
     4441 atcagcgcca tccggctacg ctcacctcac cttacgcaat gcgtgcaaat cccgcttcca
     4501 gatcggcaat caggtcgtcg atatcctcaa gaccaatatg caccctgacc agcgtgccgc
     4561 tgaaatctac ctctccagcc gggcgaatgc tgttcagctc ttccggctgg ttcgccagaa
     4621 tgagcgactc aaatccgccc cacgaatagg ccatatggaa cagcgagaag ttatcgagga
     4681 aattcgccat ctgttcgtcg gtcagtctct ttttcagcac aaacgagaac aggcctgagc
     4741 ttccgataaa atcacgctga aaatactcat ggcccggaca ttccggtaat gccggatgat
     4801 tcacccgtgc cacttccggc cttgccgaca gccagcgggc aatatggata ctgctctcct
     4861 gatgctgctt aaggcgtacc gccagggtgc gcaatccgcg gctgccgttg taggccgtat
     4921 cggcgtccag cgtttgcccc atcagatagg agttctcgcg caggcgatcc caacaacggg
     4981 cgttcgacac cgccgtgccc agcatggcgt ccgaatggcc gatggtgtac ttcgttcccg
     5041 cctgaatgga aatatccacg ccataatcca gcgctttgaa cagcacgccc gccgcccagg
     5101 tgttgtcgat cataatgaca atctccggat tcaccgcgcg gatagccttc accatccccg
     5161 gcacgtcctg gacttccatg gtgatagaac ttggtgactc aaggaataca acctttgttt
     5221 ccggacgcag aagatcgacg atacctgcac caatcagcgg atcgtaatac gttgtttcca
     5281 cgttgaattt actcaggatc ttattgcaga aatcctgggt tggttcatag gccgcccccg
     5341 tcatcagaat atgatcgcca ccctgaacaa acgccagaat cgcattggtc accgccgcag
     5401 caccacatgg gtacagcgca cagccaacgc cgccttccag ttcgctcatt gccttctgga
     5461 aggcaaagtg ggtataggtt ccgcgacgac cataaaacag ctcgccgttc gcgcgattgg
     5521 cggtggcaaa tttcttgtcc ttcacggtat caaataccag tgaagaggcg cgttggataa
     5581 ccggattcac cgctccctgg gtatagcgtt tgtcgcgacc agcaacaacc aggtgcgttt
     5641 caagcttcat tgcgtctttc ataacatctc ctgttcttaa tccgtgtgaa acctatacca
     5701 ccgcagcagt agagtttatt tcagcgttgg tctgcttttt tccagcgaac cgttcaacaa
     5761 tctgcgccgc attcaaatca tggataacgt taatcagtgt ggccggcgca tcggtaatgg
     5821 tgcccagcac caccagcatc gggattgctt ccatcggcag gcccagcgtg gtgacaataa
     5881 agatttcacc gaggaacgcc ccgcccggca cgccaccaac gataatggcg gagagcaccg
     5941 caatcagcat cgtcaggaag aaggtttcgg tggtgaattc catgcccagc acggaataga
     6001 taaagacaat ttttagcgcg gcaatcatcg ccacgccgcc cttgttgagg ttaaccagca
     6061 gcggaatgga gacatcaacg atttccgggt taattcccat cgccttaccg gcacgcagcg
     6121 tcaccgggag cgtccccagt gaagagcagg tacccagcgc ggtcgcagac ggttcaatcg
     6181 cgttacgcca gaaggctttg accgccggaa taccgccgcc aatatacgaa tagagaatcg
     6241 agccaaagac aaagtagacc agcgtggcaa ccataaacag gccgatggcg cgggcaaagg
     6301 ttaacagtag tgcagagtcc tgactggcca tggtggcggc gaagtagcag cccagaccaa
     6361 tcggcgcgac cttcataatg atcgagacga tcttcatgat cacggtattg gcgtcttcca
     6421 gcagcgacgc aatacgttta ccggcctgat ccgactggcc aattgcgaca ccggcgatga
     6481 tcgccattac gatcagcgcc agaatattgg acttagaaaa cagtccgata aagtcgctgg
     6541 tggtgatcat actgacaaaa tccatcttac cgctgcccgc ctgcaccgac tgcgagagat
     6601 cgatagtgac gccctgcgcc gggttatacc agagcgccag cgcgacgatc ccggcggctg
     6661 gaataaaggc catggcgatc gaaacaataa agataatcgc cataatgcgc cccagccttt
     6721 ttaggtcggt catactggcg atcgaagaca taacgctgat ccccaccagc ggcacaataa
     6781 tcataaatag caggtttaag aatatctgac ctattggctg gagtttactt gcaaacgatg
     6841 gggcataaat acctaataag ccgccaatca ccagagcaac taataaaata atcgacgatc
     6901 tgtagggttc gagtcgtgac cacataatcg gtacctttag aataataatt aatgagatta
     6961 aattcacaat gtgatgagtt tccgtttcgc ctccttttat tttgtgacgt aactcaccta
     7021 agttgttatt ttttcatttt gccagcaagt tatttcctgt gattcaatag ttgcatgttt
     7081 aaaacgcgaa tgtaacggcc tattcgtacc gtttttgcaa atcacttgtg aattaaagga
     7141 aactatgagt acgccaattt cactcaagca tctggagttt tttactaaaa tcgtcgactg
     7201 cggaggattg tcagaagccg cggcgcagct caacgtatcg ccgtctgcgg tcagcaaaag
     7261 tctggctgcg atggaagaca cgctgggcac gacattaatt aaacgcacca cccgcagtat
     7321 taccctgacc gacgccgggc aatatctctt caatcgcgct aataagcttt tgaaagaatt
     7381 cgatgaaacg ctgaatacca cttcaggtta ttaccacagc ccgcagggtg aattacgcat
     7441 aacctgctca attgcgtttg gttattcccg gctggtgaac ctggtagata aatatcgctc
     7501 ccagtttccg gatgtgaatc tgtatatcga tctcaacgat aacttcgtga atctgaacga
     7561 aacggatttc gacatcgccc tgcgcatctc caccgcaccg ccgcagaact atgcgatgcg
     7621 caagctggtg cctgttcgct gggcgtactg tgcctcaccc ggctacctcg ccaaaaaagg
     7681 catgccccag cgtcgaagcg atctggtgga tcatgattgt ctggtttatc caggcctcac
     7741 gccggtactg aaagtggcgg atgaacagga tcgtctgcat cagttgaaac tgcatatgcc
     7801 gatccaggcc aacagcagtc tggtattgct gaagtcagta ttagaagatc agggagtggc
     7861 gtatttgccc acctatctga ttggcgatca tattcaaaaa gaagagataa cgccgctgat
     7921 gctcgacggc actatcacct gtgaaactca cgccctgtat gcgctgtact ttcccagcaa
     7981 gtacagcaat ccgaaggtgc gatcgtttat cgattttctg gtggcggaac tcggcccctt
     8041 gcccgcctgg gacaactgga tccctgagta agcccagccc acctgaaaat gggaggcgct
     8101 ccacattttt tgcgcgatcc ccccgtctgg ctctatcctt aagcctatga ataaaattgc
     8161 tgaactcaaa cgcgccaagc gactggcgct ctcattgctg ctgattgccg ctgccacctt
     8221 cgtcatcacg ctttttctgc cgcctaactt ttgggtactg gggatcaaag cgatcgccga
     8281 agcggcgatg gtgggcgcgc tggcggactg gtttgccgtg gtggcgcttt ttcgccgggt
     8341 gccgatcccg tttatctcgc agcacacggc gattatcccg cgcaataagg atcggatcgg
     8401 cgaaaacctc ggtcagtttg tgcaggaaaa atttctcgat acccagtcgc tggtcgcgct
     8461 gatccgccgc catgaaccgg cgctgttgat cggcaactgg ttcagccagc cggaaaacgc
     8521 ccagcgtatt ggccagcatc tgctgcagat catgagtggt tttctcgaac tgaccgacga
     8581 ctcgcgcatt caacggctga tcaagcgggc ggtgcacaag gccatcgaca aggtcgatct
     8641 ctccggtacc agcgcgctaa tgctggaaag catgaccaaa aacaatcgcc atcaggtgct
     8701 gctcgacacg ctgatcgccc aactgatcgc cctgctccag cgcgacagct cgcgggcgtt
     8761 tatcgcccga caggtagtgc actggctgga gaccgaacat ccgctgaaag caaaaatcct
     8821 gccgaccgaa tggctgggcg aacacagcgc cgagctggta tctgatgccg ttaactcctt
     8881 gctggatgac atcagccacg atcgcgcgca tcagatccgc catgccttcg atcgcgccac
     8941 gtttaagctc atcgataaac tcaaacacga tccggagatg gccatgcggg ccgaaagcct
     9001 gaaaagctat ctgaaggaag atgaagcctt caaccgttat cttggcgagc tgtgggcaga
     9061 cctgcgccag tgggtgaaaa ccgacattaa cgccgacgat tcccgcgtga agcagcgcat
     9121 cgccagcgcc gggcagtggt ttggcgaaac actggtagcc gacagcgccc tgcgcgcctc
     9181 actgaatggg catctggagc aggccgcaca taaagtggcg ccagagttcg ccaccttcct
     9241 gacgcgccat attagcgaca cggtgaaaag ctgggatgca cgcgatatgt cgcagcaaat
     9301 cgagctgaac atcggtaaag atttgcagtt tatccgcgtc aacggcacgc tggttggcgg
     9361 ttctattggg ctggtgttat atctgttgtc gcaaattcct tccctgctga cgctggcgaa
     9421 tttttaagga gaaaaattca atgacgatga acatccgcat tttttccctg cgcgaaacac
     9481 ctgaaaaact gcacgaggtc accgcttact ttcagcaaca atgggcctca gaagactccg
     9541 tgaaggtata cgaagatgcg ctgcatcgtt gcattggcgc aaagaacccg ctaccgcagt
     9601 ggtactggct gcaggacggc gacagcatcg ttggctgcgc cggattgatc actaatgatt
     9661 ttatcagtcg cggcgaactg tggccgtggc tatgcgcgct ctatgtcgat cctcgctatc
     9721 gtggtcacgg tctggcgttt cgcctgattg aacatattgc gcagcaggct aaacagctag
     9781 gctttatgca gctccatttg tgtactgacc tggaaggttt atacgagaaa gcgggatttt
     9841 actttgacgg accgggctat catccgtggg gggaagtctc acgggtctac agtcgtaatc
     9901 tgtaagcgca caattgttgt acatcaataa agccagataa attgcatggt tataatgcga
     9961 cgtcttttta ctgtctcccg tgttacgggg aaggaaaatc atgtcgctaa tcaccgattt
    10021 acccgccatt tttaatcaat tctccgacgc ccgtcagaaa ggttttctca ccgtaatgga
    10081 tcttaaagag cagggtatcc cgctcgttgg gacctattgc acctttatgc cgcaggagat
    10141 agcgatggcg gcaggcgcgg tcgtcgtttc gctatgctca acctctgatg aaacgattga
    10201 agaggccgaa aaagatctgc cacgaaacct gtgtccgctg atcaaaagca gctacgggtt
    10261 tggtaaaacg gataaatgtc cgtacttcta cttctctgac ctggtggtgg gcgaaacgac
    10321 ctgcgatggt aaaaagaaga tgtacgagta catggctgaa tttaaagcgg tacatgtgat
    10381 gcaactgccc aacagcgcca gtgatgcggc ttcgcgggcg ctgtggaaag ccgagatcct
    10441 gcgtctgcag caggcaatcg aagcccgttt tggcaccccg attaccgaag ccgcgctacg
    10501 tgaagccgtc attctcaaaa accaggaacg tcgtgcactg gcgaacttct accgcgttgg
    10561 tcagctcaac ccacccgcac tcagcggcag tgacattctg aaagtcgtct acggtgcaac
    10621 cttccgcttt gataaagaag cactgatcga cgagcttaat agcatggccg agcgggtaca
    10681 tcagaaatgg caggccggga aacgtctggc gtcgcgtcca cgcatactga taaccggctg
    10741 ccccatcggc ggcgcggcag aaaaagtggt tcgtgccatt gaagaaaacg gcggttgggt
    10801 ggtgggttat gaaaactgta ccggtgcgaa agccactgaa cagtgcgtgg aggaaactgg
    10861 cgacgtctac gacgcactga ccgataaata cctcgccata ggctgctcat gtatttcccc
    10921 taacgatcaa cgtctgcaaa tgctcagcca aatggttgaa gagtaccagg ctgacggcgt
    10981 cgtcgatgtc attttacagg cttgccacac ttacgccgtt gaatcactcg ccatcaaacg
    11041 acacgtccgc caacagcaca acattcccta tatcgctatt gaaaccgact attccagctc
    11101 ggatatcggc caacttagca ctcgtgtcgc cgcgttcatt gaaatgttgt gaggaacagg
    11161 gatgacatac tcaataggga tcgattccgg ctccacggcg actaaaggta ttttgctgga
    11221 aaggaacgtc atcagacgtc gcttcctctg cccaacgcca tttcgccctg ccgaagcgat
    11281 cgcgcaggca tgggaaacgc tgcaggcggg gctggacgat agaccatttt taaccctcac
    11341 tggctacgga cggcagcttg tggattatgc cgacaaacag gtcactgaaa tttcctgcca
    11401 cgggctggga gcacgcttgc tggctcccgg cacccgcaca gtgattgata tcggcggtca
    11461 ggacagtaaa gtcatccagt tagatgatga tggcaacctc agcgatttct tgatgaacga
    11521 caaatgtgcg gcagggaccg gacgatttct ggaagtcatc tcacgtacgc tcggcgccag
    11581 cgtagagcag ttagatgcga ttaccgctgg cgtcgaacca catgccatca ccagcatgtg
    11641 tacggttttt gccgagtcag aggtcatcag cctgcgctct gcgggtgtcg cgccggaggc
    11701 aattttagcg ggagtgatca acgcgatggc ccgacgcagc gcgaatttca tcgggcggct
    11761 ttcagggcag gctccactgt tatttaccgg gggagtaagc cactgtcacg cctttgcccg
    11821 tatgcttgaa ggccacgttg gcattcccgt acacacgcat cccgatgcgc agtttgccgg
    11881 ggcgattggg gccgcgttaa taggccagcg tcaggggaaa cgtaagtgaa ggaagcactg
    11941 ttcctgtttc attctaccct cggcgtcatc aaaacgcgta aagcgctaca ggctgcgggt
    12001 atgtgctttc gggtggcaga tattccccgc gagctacgcg gtggctgcgg gctgtgcatt
    12061 tacatcgact gcgttgctgg caaggaggat gagtggataa ttccgggtca taccgaatct
    12121 atctaccgtc ttgaaaacgg aggctggcgc tgccttgcca cttttccccc ttcctgaacg
    12181 taccagggga cttagtttta ttttactttt cattatcatt tacgcatgta atataacaat
    12241 tatcagctaa cagcgcgaaa tgagagtccg tatgtcccag ggaagcccag attcaaatcg
    12301 tcatgccatc agcgtcgcgc tttttggcat gctggtctta acactgggta tgggaattgg
    12361 gcgctttctg tatacaccaa tgctgccggt actgctgtcg gaaggtcaat ttacatttga
    12421 gcaactctcc tggattgcca gcgccaacta cgccgggtat ctggcgggaa gcctgctctt
    12481 ctccttcggg ctcttccatc ttccctcacg cttacgcccg atgctgctaa cgtccgcgct
    12541 cgctaccgca gggctgattc tggcgatggc aagcttaacg cagcccgcgc tggtgatgct
    12601 gatccgcttt ctggcgggcg tcgccagtgc aggtatgatg atctttggct caatgatcgt
    12661 tctgcatcat acccggcatc ccttcgtgat cgcggcattg ttctccggcg ttggcgcagg
    12721 cattttgctg ggcaatgaat atgttattag cggtctgcat tttgcgcttt catcgcacac
    12781 gctctggctg ggcgcagcgg cagcctcggc tctgttcttt gtgctactgg ttatactcct
    12841 gccatctcgc aaccacgtgc tccccgctgc ggccccggta aaaacagagc atcagcctat
    12901 atcctggtgg ctgctggctc tactgtacgg gctggccgga tttggctaca tcattgtcgc
    12961 cacctacctg ccgctgatgg cgaaaagtgc cggttcgccg ctgttgactg cccatctctg
    13021 gtcgctggtc ggcatatcga taattccggg gtgtttcgcc tggctgtggg ccgcccgacg
    13081 ctggggagta ttgcaatgcc tgacggcgaa tttgctgatt caaagcgcct gcgtggtcat
    13141 gacgctcgcc agcggctcct tgccgctgct ggtgataagc agcatggggt ttggcgcaac
    13201 gtttatggga actacttcac tggtgatgcc gcttgcccgt caactaagcg tgccgcgcaa
    13261 tattaatctg ctgggcctgg tcactctgac ttacggcatt ggacaaatac ttggtccgct
    13321 attaaccagc ctgctgggaa gcggcgcaca ggcgatcgtt aacgccacgg tgtgcggcgc
    13381 ggtcgcgttg tttattgcgg cgcttatcag cctcacgcaa ttatacaaac agcgtttcgc
    13441 ctcgcccaaa agagtataaa cggcaaacat ctaaagaagt tatattcgga ttagtccgca
    13501 attaaatgtc agcatttaat aaaccgcaaa taatcggcaa ttacccgtca gacaatttat
    13561 aattcccggc tgttcattta taaactcaat ttaaaatgcg taaaaatgga catattaatt
    13621 caacatcaac accatcttcg ggaaaggcac atgtcgtggt ttaaaaaaat actactgggg
    13681 ttaattattt tggcgggttt aattggtacg ctaaaggatt ataaagactt tggcctgttt
    13741 ggcgcactgg gattgtttat tatcttcctg ttatcaacaa cattcttatg gcaatgggcc
    13801 tctggcaagt taccggagat aacaaagtta catgccatac ttattttact ggccagcgcg
    13861 gtagcctcta tttttgttat caatatggca attgccggaa atttgcatgt ggatttaatg
    13921 gaagtcatgc gcgttaccat tacccataat ccgctttttt atctgatcct ctgcgtggtc
    13981 gcatgggtaa aagtgggcat ctggcaatgg ctgtttagcg gtgtacagat gaaagaaagc
    14041 cagccggttt aaactccaat agatgtaaaa aaggcgtctt aaccaagacg cctttttcgt
    14101 actagtataa ctacttagaa ctgataggtc agacccgcaa caacctgatt gtcgccgtct
    14161 ttgccatcga gcaggttaat tttgtaaccc acatcagcaa ccatgttttt gttgaagtag
    14221 tagtctgtgc ccagcgcaac gtattcggtc agatcagtgt tgttgttgtc acgtgcatga
    14281 acgtatgcca cgttcggacg cagaccaaaa tcaaacacat aggccgccat cgcttcaaag
    14341 tgctgcgctt tgtccgcatc ctgaatcagg ttgtgggatt cgccgtacat ggtcgcaacg
    14401 tagatagcgt ttgcatcata tttcaggcca gcaccccaga attctgcgtt ttcgccatcc
    14461 caaccatttt gtttctgctg agcagtcaca gaactgttgg tgtaggctgc aatggcagat
    14521 acgccggaat cagcgatatt gtcgtagcct agggagaagc cgtagccatt gccgtgctgt
    14581 ttcgtcggat ccttatcgga atcatcctga ccctgatatt gcgcgcccag gctcaagcca
    14641 tcaacggcac caaacagatt tttggtgcgg agtgttgcaa cgccagaagt gcgtgtagta
    14701 aggaagcggt cagtattttc ataggagtca ccgccgaact ctgaaagagt gtcagtgtaa
    14761 gctcccacgt cgtaagcgat accgtagtta cgaccgtagt caaagctaac gtcatggcca
    14821 taatccagac cagcaaacgc cagacgtgta ttaacaccat tctgagaacc ttctgcttta
    14881 gcggcatcaa actgactttc aaactgacca tagccagtca gttgatcgtt gatttgagtc
    14941 tcaccgcgaa aacccagacg tgcgtaggta ccgtcagcat cggtgccgtc agtccaggag
    15001 tggaccgctt tcactttgcc gtacaaatca agtttgttgc catctttatt ataaatttcc
    15061 gctgcatgaa cggaagtgac gcctaatgcc atcactgcta ataccactgc tgactttttc
    15121 atatttttac tcacttttaa ttgtgaattt tgctatcaac tttgttatga aggcaggaag
    15181 tcctcataaa aaagccccct gaatatcaag gggagaaatc aataacacac caataaaggc
    15241 aataatgaag tggcaataaa taattcacta ctcggatttc agttaaatcc aggctaagag
    15301 cagatatgtt tactcttgat tctcactctg attaatagag cgatgtaaca ttaacgcctc
    15361 agcgataata tcttgtttac ttttacgggt ttcaaatgcc agcatccgaa catattccca
    15421 tagagaagta tcgacacggg cacttaatag aaccatatct tttgatcggg ttcccctggc
    15481 ttttcggata tcagggtaat ctcgagaggg catcgtcatc atctcctgaa cgcaataaga
    15541 cgcttatggc gatgaaatat gcagtcagtg taaaaacatg tcaacggtaa aaaacattca
    15601 caatcgtaat aaaactgtta ataaatagca gaaaaatgga acgatatttc aagtgaaaga
    15661 taacttgttt atagaataat gtgtaatttt aactttacat atattcgttt ttattcattt
    15721 gattaaaaaa gcatgaatca ttcacatgga taatgatata cagtcaaaac atcattgcag
    15781 ccaataggtt acatgtcgtt attaatgtct acttttacgc aaaccacgtg tttttatgcg
    15841 ctgttatgcc aggcggccct gccctaacca cagcggaaat tactttgatt ctcacttaat
    15901 acagaccagt tttgtctaaa aatacgcacg aaaaggtaaa aataaggtaa atagcgcatt
    15961 ttttcgcaag caaaaataag ttgtttttaa ttgatgaaaa tcaatttaca tcacacaggg
    16021 gcagcgaaaa aaatgatcat tgaagactat ggaaaccatt ttttacatga ggtttaagac
    16081 gtgaaaagaa aggttgctat gcaatgccga gcgggccgga acagcccgcc tgggagaggt
    16141 ggtaaaatca agcgttaact ttatccagcg gccaggagtc aaacagatag ccatcgaagt
    16201 cgatgtcatc aacatttgaa aactccagca ggcgctgttt gacgttttcc agatgctgcc
    16261 acatcgccag cttggccgca cgggcatcct ttttgattaa cgccgccagg atctgtttgt
    16321 ggtcacccat ccactcttta cgatagtggg tatcatcgag atggctatga agctggatcc
    16381 acatagggtt gttctcgcgc cactgccatg actggcggaa cagctccacc agcatgctgt
    16441 tatgcgtggc ctcggcgata gcgagatgga actgcatatc accgctttca gaaccattcg
    16501 gttcgctgga ggccagctcc cgctcttcca gttgcaacgc ctggcgcatt ttgacgatat
    16561 cttcgcgggt ggcctgcagc gcggcaaatt cggcgatgtt gctttccagc agctgtcgcg
    16621 cctggagcag ctcaaacggg cctgcatcat tgcaatgatt cacatccgaa ctgtcgatgg
    16681 tctgcgcatc cgcattgtcg agcacgtaga tcccagcgcc acgacgcacg tccaccagac
    16741 ctttaatttc cagcatgatt aacgcttcgc gcaccaccgt gcgagtgaca ttgagtctct
    16801 cggcgatttc acgctccggc ggcaagcgct caccaggctg gtacggcgtc tggacaatca
    16861 gatcgcggat cattgcaccc acttcctggt agggtctttg ctgagaagtg ttcgatttca
    16921 tcgtgttatg tccgtcagat gcgtcaattc agaatccgga ggctggatga ctgcgcacac
    16981 cttatccggc ctaccaataa cgttttttcg cctgaactat agcatttgcg ggaagccaaa
    17041 aacagaaaac gggtcaacca aattagtatt ttgattgacc cgtcatacct gggaggttat
    17101 tcgtcagcgc ttaacgctgc aacgcactcg cgtgcgccgt gttcacacaa ctgttgatac
    17161 gccgcggtaa ccgtcgcaac aaagtcggtg ttttccgcca gatcatgacc aaaaatgccg
    17221 ctcaacccca gcagcgccgt cacgcgttcg gctccctgga actgttggtt aatgcgctgg
    17281 aattcggcct gcattgggtc gacaacatca atgacctgcc cctgttcatc cacaccgtgg
    17341 gtgtagcgca tccagcccgc gatgcccagt gccagatgac gccagccgct accgttttgc
    17401 agatgcagac gcaccggatc cagcaggcgc tgtggcagtt tctggctgcc gtccatcgca
    17461 atctgccagg tacggtggcg cagagacggg ttgctgaaac gctcgatcag cagcgtcgcg
    17521 taggcgttga gatcggtacc ttccggcatc gacagcgttg gcgcttgctc ctgcatcatc
    17581 agcgcaaacg ccgctttgcg gtatgctgga ttggtcatgg tgtcagcgat ggtttcatag
    17641 ccgccgagat agcccagata agcaaggaaa gagtggctgc cgttgagcat gcgcagtttc
    17701 atcatttcaa acggtactac gtcggcaaca aactgtgcgc cgactttgtc ccagtcaggg
    17761 cgaccgttaa caaagttgtc ttcaatcacc cactggcgga acggttcgca ggcgatagcg
    17821 cacggatcgt aaacgcccaa ctggtcggca atctcctgca acgtttccgg cgttgccgcc
    17881 ggaacaatgc ggtctaccat ggtacacggg aaagtggcgt tcgcttcaat ccactgcgcc
    17941 agctgcgggt cacgcgcctg cgccaggccc agcaccgcga ctttcgccac atgcccattt
    18001 tcacgcacgt tatcgcagga catcacggta aaggccgcca gcccctgctc acgacgcaga
    18061 tgcagcgcct gtacgatgta accaatcgcc gatttcggcg cggccggatt tgccagatcg
    18121 tgtttaatca gtgggttatt gagatctaac tggccgctgg cagcatcggt gcagtagcct
    18181 ttttccgtga ccgtcagcga gacaattgcc gtctgcgggc gtgccatggc ctgtaaaata
    18241 ccatcacaac catcaagctc cgggtgcagg gcttctttca ttgagccgat cactttcagc
    18301 acggtgttgt ccgcgccttt ttccgccacg gtatacagca attgttgctt gcgcaggttt
    18361 tcaatcagta tgcagtcatt acccggcatc aggttaactt cacagatacc ccagtcgctg
    18421 tcggtggttt ccagcagatg gtgggtgtac agcgcctgat gcgcgcggtg aaaagcgccg
    18481 catcccaggt gaacaatgcg ggattgcaga cgagagctgt cccatgcggg gcgcgcaacc
    18541 ggcaggttgc tattggcaat tgtcgttgtc atcgtgaact ccagatcccg tcggaaagac
    18601 caacggtgag aaaagaaaaa agccggccag acaggcgacc ggcaacactg ctttagcggc
    18661 taaagaaagc gcgctggata gccatctcaa cgccacgcac ttccgccagg cctttcaggc
    18721 gaccaatcgc ggagtaacct gggttggttt tctttttcag gtcgtcaagc atctggtgac
    18781 cgtggtccgg gcgcataggg atcagatcct ctttgccctc ggctttacgg cgctgttctt
    18841 cctcaacgat cgctttcacc acttcgtaca tgtcaacgtc gccatttaga tgcgccgctt
    18901 catggaaggt tttcgggtta tcttcacgca gcgtggagcg caaatgggtg aagtaaatgc
    18961 gcgggccaaa ctgtttgatc atgtcgacca ggtcgttatc cgcacgaacg ccgtaggagc
    19021 cggtacacat ggtgaaaccg ttcgccatgc tgttgaccgt atcgaccatc cactgcatat
    19081 cttccacggt ggaaacaatg cgtggcaggc caaggattgg gcgcggcgga tcgtccgggt
    19141 gtaccgccat gcgcacaccg acctcttctg ctaccggaat aatcgccttc aggaagacgg
    19201 caaaattctc acgcagcgca gctttatcga tatccttata gcgttcaaga tgctggcgga
    19261 actggtcgag cgtgtagccc tcttccgcgc ccggtaaacc ggcgatgata ttgcgggtca
    19321 gacgtgcttt gtcttcttcg ctcatggtgg tgaagcgttc attcgcctgc gcaatctctt
    19381 cggcggtgta gtccgcttcc gcgcccggtc gtttgaggat atgcagctca aaggcggcaa
    19441 attcaatttg atcgaaacgc agcgctttgg agccgtccgg caggacgtat tccaggtcgg
    19501 tacgggtcca gtcgagaacc ggcataaagt tgtagcatac ggtacgaatg ccgcactcgg
    19561 ccaggttacg caggctttgc tggtagttgg caatccactg ctgatagttg ccggaacggg
    19621 ttttaatgtc ttcgtggatc ggtacgcttt cgacgaccga ccataccagg cccgcctgct
    19681 caataatggc tttgcgtttc aggatctcat caaccgtcca cacttccccg ttcgggatat
    19741 ggtgcaaggc agtgacaacg cccgttgcac ccgcctgacg cacatccgct aaggtgaccg
    19801 gatcgttagg accataccag cgccatgtct gttccatgtt ttattcctcg tttacgttat
    19861 ggactcgacg atatggcaca taaattcctc cttttggtat tacatgtcaa cctgaagcga
    19921 taaattggtt aaccaaatca cgatatctgc tgaccatacc gctaattaac ggccatacaa
    19981 cccagtatta atgtaaacat gtaacgcaat gtgacatcca tcgcatcata ggttgaccaa
    20041 tatctgtaac atctcaacca aaatcataat agttcaacca aagtaaggta gacgttatat
    20101 gcacgttctc aatattctgt gggttgtatt cagcatcggc ctgatgctgg tgctcaattt
    20161 aagattcaag ataaactcga tggtcgctct gctgttggcg gcactctcgg tcggtatgct
    20221 ggcgggaatg gatttaatgg aactgctgca taccatgaaa tccggttttg gcagcacgct
    20281 gggtgagctg gcgattatcg tggtattcgg ggccgtcatc ggtaagctga tggttgattc
    20341 cggggcagcg catcagattg cccatacgct gctggcgcga ctcggtctac gttacgtgca
    20401 gctgtcggtg atcattattg gtctgatctt cggcctggcg atgttctatg aagtggcgtt
    20461 tattatgctg gcaccgctgg tgatcgtcat tgccgcggaa gcgaagatcc cgttcctcaa
    20521 gctggcgatt cctgcggttg ccgccgccac caccgcccac tcactgttcc caccgcagcc
    20581 gggtccggtc gcgctggtta acgcctacgg cgctgacatg ggcatggttt acatctacgg
    20641 tatcctggtg accattccaa gcgtgatctg cgccggactt atcctgccga aattcctcgg
    20701 caacctcgat cgtccaacgc cgtcattcat gaaggccgac gtaccggttg accagaacaa
    20761 cctgccgtcc ttcggcgtgt ctattctggt gccgctgatc ccggcgatca tcatgatatc
    20821 caccaccatc gccaacatct ggctggtgaa agggacgcag gcgtgggaag tggtcaactt
    20881 cttaggctcc tcgccgattg cgatgtttat cgccatggtt gtcgccttcg tgctgtttgg
    20941 taccgcgcgc ggtcatgaca tgcagtgggt aatgaacgcc tttgaaaacg cggtgaaaag
    21001 catcgccatg gtgatcctga tcatcggcgc gggcggcgta ctgaagcaaa ccattatcga
    21061 taccggcatc ggcgatacca tcggcatgct gatgtcacac ggcaatattt ctccctacat
    21121 catggcgtgg ttgataaccg tgctgattcg tctggcaacg ggtcagggcg tggtctcagc
    21181 catgacggcg gcggggatta ttagcgcagc aatcctcgac ccggcaaccg gtcaactggt
    21241 gggcgtcgac ccggcgttgc tggtgctggc aacagcggct ggctccaaca cgctgaccca
    21301 tatcaacgat gcttcgttct ggctgttcaa aggctacttt gatctgtcgg tgaaggatac
    21361 gctgaaaacc tggggtctgc tggagctggt aaactccgtg gttggcctga taatcgtgtt
    21421 gatcatcagc atgattgcat aacgttgata ccgctctggc ccacagcgcc agagcggttt
    21481 tccatcctgc ctcaacaatc ctcaataatc agatataccg ccttcaccgg accatgcacc
    21541 ccaaccacct tgataagctc aatatccgcc gtcgagctgg gtccactgat gatattaatg
    21601 cacgatggca tacgctcacc ggcctgtgct ttctgatgca gtttttctgc cagctgcgcc
    21661 acgcgcggca gaatggagct tttacgcagc acgaaaatcg aggactccgg caacaggctc
    21721 agggagcgcc cgcgctccgg tgcggaaaac agcaccacgc cgccggactc ggtcaggcca
    21781 tattcggcat acaccacgcc gactttcgcc tgctcggcct gggtaatatt ttcgctacca
    21841 cgcgccggat cccagaccac ggcgttgcat tcctgctgca agcgttcggt gatgcccagc
    21901 tccaccagcc ggctgtcgcc gctcagcac
//
