LOCUS       c00128_NZ_JADC..       12682 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JADCKK010000069.1 Anaerotignum lactatifermentans strain DSM
            109233 seq69, whole genome shotgun sequence.
ACCESSION   c00128_NZ_JADC..
VERSION     c00128_NZ_JADC..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:16:36
            Original ID  :: NZ_JADCKK010000069.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12682
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12682
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2588:11563]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2589..11563
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="1"
     protocluster    1..12682
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2588:6496]"
                     /cutoff="2000"
                     /detection_rule="(PFL_6_pcresol and (Gly_430_pcre or
                     Gly_radical) and hpdC and Radical_SAM and not NRDD)"
                     /neighbourhood="10000"
                     /product="p-cresol"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      2589..6496
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(PFL_6_pcresol and (Gly_430_pcre or
                     Gly_radical) and hpdC and Radical_SAM and not NRDD)"
                     /neighbourhood="10000"
                     /product="p-cresol"
                     /protocluster_number="2"
     cand_cluster    1..12682
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /detection_rules="(PFL_6_pcresol and (Gly_430_pcre or
                     Gly_radical) and hpdC and Radical_SAM and not NRDD)"
                     /kind="chemical_hybrid"
                     /product="GR_fatty_acids"
                     /product="p-cresol"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..12682
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_fatty_acids"
                     /product="p-cresol"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /rules="(PFL_6_pcresol and (Gly_430_pcre or Gly_radical)
                     and hpdC and Radical_SAM and not NRDD)"
                     /tool="gutsmash"
     CDS             complement(172..1074)
                     /locus_tag="ctg128_1"
                     /transl_table=11
                     /translation="MEEVNVYNTYVTNDENKKIYYLDVDEISDFPDHPYHVIEDESLME
                     LSESIKKYGVMVPLIVRLVDNKYQMVAGHRRKAASILAEQYKVPCIIKELSDEDAIITM
                     VDSNIQRENILPSEKAFAYKMRMDAIKRKGGRPRKNNVVPLAHNFQKKTSRQLIGEQVG
                     ESQDQVRRYIRLTYLIKPILDMVDEKKIALRPAVELSYLSSESQGILLEVMGQLDCTPS
                     HAQAIQLRKLEEESALCFFTIEQLLSEQKGNQKEQLKVPLEKIERYFSPGTSPKTMEKT
                     ILEALEMYYRLKVQERRKK"
     CDS             complement(1297..1572)
                     /locus_tag="ctg128_2"
                     /transl_table=11
                     /translation="MDKPFKIHSKFQPTGDQPQAIEKIADGFQNGLKFQTLVGVTGSGK
                     TFTMANVIEKIQKPTLVIAHNKTLAAQLYNELKEFFPENAVEYFVS"
     CDS             complement(1749..2429)
                     /locus_tag="ctg128_3"
                     /transl_table=11
                     /translation="MHERIWANWQDFVGKLDIYPMIRPYLETSQITIHEVPAKTCISNA
                     ADEGYRIVYILQGSVKVVSLTYRGIRILLDEIGVGSFSGHISRMRGYSFDANIIAETPC
                     VYLEFPDQLFCQLMENPAFALEFYRSTSSRTYQMYRKVFSLTLFTAEENTAMYCLMHPA
                     RLQSYTLDEICEEIGISRRSLCYVLKKWRKEGILKGKEKRDRIADHEQLMQIAEHIRQF
                     YDIP"
     CDS             2589..5270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     p-cresol: Gly_430_pcre"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     p-cresol: PFL_6_pcresol"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Gly_430_pcre"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_6_pcresol"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_4"
                     /sec_met_domain="Gly_430_pcre (E-value: 1.2e-56, bitscore:
                     178.5, seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_6_pcresol (E-value: 0.0, bitscore:
                     1155.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLQEILKARGITDEQLKEVQEQDIPAAAESFQRIMDIYYLLKVT
                     ADMESAYWYNRVWWENDGDLLEVRRSKAVAASLAHSTPTILPYEKLVMNKTKHLRGAFP
                     FPWVCASFFNSLAESLMEEAEAPAENEADSVSVVGAGGGNVTESYGEVISIAKKFGMRK
                     ENIPVLVKVSKYWDGISVEDISTKYAKTLPGFEQFQNIMDSVLVMFDSFAIPQGREVMN
                     YYMPLQYGFDGILELCDEKIAKTMGEAGGDGVLGMSRGYYYAAMKEIVKGLSQWCENYA
                     RKAEDLASCEPDEAYKKNYLEIAQVMHNIAHKRPSTFREALQMTLCLHLGVVNEDPQSG
                     QSIGRLGQVLQPFYEKDIADGTTTEEEVVELLELYRIKITCIECFASAGVSGGVLSSNT
                     FNNLSLGGQNYDGLSAVTPLEYLIIEAGMRAQTPQPTLSILYDEKLPEDFLMKAAACTK
                     LGMGYPAWMNNQVGMNFMLRQYGPEGMDLYDARAWCLGGCLESAPGCFLPLEYNGKVTM
                     IPGGASPTCGTGIHFTGLPKVLELVLTNGVDKRTGKQVFPPHNKKLETFDELLDQWKEY
                     LDISNRIVNKVNNIQMDVWRKYNMPAVNSLLKPDCFKKGQHIGNCGARYNACINFESCG
                     TITFINSLASLKKNVYDTKKYTLEEMTDAMLHNFGFRTAYDTGVFSPDYRESTDDAQKY
                     AEIFADCINAPKYGNADPYADQLLRDYHMYLLHYLPTLESFFGKPEYLCQISVSTHGPQ
                     GFITLATADGRLAGTTYSDGSVSAAPGTDKNGVYALFESATVYDHSQNQNAQMNLKLHP
                     SSVQGVQGTRKLLELVRTYMRKGGFHVQFNVVSSDTLKEAQKTPDQYRDLMVRVAGFTQ
                     YWCEIGKPIQDEVIYRTEYEEV"
     CDS             5287..5553
                     /gene_functions="biosynthetic (rule-based-clusters)
                     p-cresol: hpdC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_5"
                     /sec_met_domain="hpdC (E-value: 8.4e-25, bitscore: 76.3,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHVECINYINLDCEKGMCALSKQIVPIDGNGSDACGHFQAAPVC
                     GNCACFADADKHGIGTCKGFEKENWTYAKCGAFCCEHYKAARG"
     CDS             5510..6496
                     /gene_functions="biosynthetic (rule-based-clusters)
                     p-cresol: Radical_SAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_6"
                     /sec_met_domain="Radical_SAM (E-value: 2.2e-25, bitscore:
                     79.7, seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00049, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVLSAVSTTKQHGGKPMDARGHIFDIQSFSVHDGPGCRTTVFMTG
                     CPLQCRWCANPESWIYGKHLMFAQASCKWDKGCDVCLSVCPTGAITMEPGQPPQVDWNK
                     CKDCHDFPCTSICPNRALKQCVREYTSEELLQILRRDFSSWGSNGGVTFSGGDPITQHD
                     FLIEVLKDCHKLGIHTAIETSAHFPREKFLDVMQYIDFAFIDVKNMDSEAHKAGTSVGN
                     ELILDNIRALKQSGWKGRLVLRQPTICGYNDSEENAKKLISFMKENDLFEINLLKFHRL
                     GQTKWEQLGKTYDYATGGEMTDEAMTALQSLYLDAGIACYIGHHTSF"
     CDS             7002..8426
                     /locus_tag="ctg128_7"
                     /transl_table=11
                     /translation="MGGFFGVTSKQDCVLDIFFGVDYHSHLGTRRGGMVIHSREKGFQR
                     QIHNIENTPFRTKFEKDLIDFQGHSGIGCISDSDPQPLLVRSHLGLYAITTVGVINNAD
                     ELIKNYFSDHGHQFMAMSSGKVNATELIAALINQKDDLVSGILHAQEQIDGSATILILT
                     EDDSIIAARDKMGRLPVLIGKDHEGYCVSFESFAYTKLGYENVYELGPREIVKITPDGY
                     ETLNPAGKDMKICAFLFSYYGYPNSNYEGINVEVMRYKNGEIMAANEKKNGTLPDVDYV
                     AGVPDSGIPHAIGYSKESGKAFARPFVKYTPTWPRSFMPANQKVRNQVAKMKQIPVPEL
                     IEGKKLLFVDDSIVRGTQLRETVEFLYRSHAAEVHMRSACPPIMYSCKYLNFSSNGSDM
                     DLLARRVVQELEGDEGHKHLDEYADASTERGKCMLRSICEKLGFDSLGYQSLDGLLDAI
                     GIDRDKVCTYCWNGKG"
     CDS             8552..9415
                     /locus_tag="ctg128_8"
                     /transl_table=11
                     /translation="MAAKVYFSREITPEKVLELYKMAGKELTGNIAIKLHSGEEGNQNF
                     LKPDFWKPVIDFVGGTVVECNTAYEGERNTTEKHKALLTRHGWDAYFKVDLMDAEGPDM
                     VLEIPKGKQIQKNYVGKHLADYDSMLVLSHFKGHPMGGYGGALKQLSIGVASSFGKAYI
                     HGAGEPEKIWTADHDAFLESMADAASSVVEYFKGNVIYVNVMKNMSVDCDCCAVAEDPC
                     MKDIGILVSLDPIAIDQACLDLVYAADDPGRDHLIERIESRNGVHTIKAAAALGFGSRE
                     YDLVEV"
     CDS             complement(9529..10224)
                     /locus_tag="ctg128_9"
                     /transl_table=11
                     /translation="MNYLNLEEFEKKLGYHFADKHLLLLALTHSSYANENKKGSHENNE
                     RLEFLGDAVLDMVVSEYMYRKFPEMPEGELTKLRAAVVCEGSLAGLSRKLGVGRNLFLG
                     KGEESTGGRNRDSILADAFEAIIGAVCMDGGIEAASTYVMRFMEDQIAQTKTNFRNLDC
                     KTHLQEIIQKISKVPVHYAIVDEKGPDHNKVFVAEVTHEGKVLGQGSGKSKKEAEQNAA
                     NAALEKMKA"
     CDS             complement(10226..10456)
                     /locus_tag="ctg128_10"
                     /transl_table=11
                     /translation="MDETVVMQIIADQLHISADSLREETSFKDIGADSLDLFQIISALE
                     EAYDIEFDNDAAENMKTIGDALDYIRRVVEK"
     CDS             complement(10574..11563)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: FA_synthesis"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_11"
                     /sec_met_domain="FA_synthesis (E-value: 6.6e-105, bitscore:
                     340.3, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQKIIVALDAMGGDLAPVETVKGAVDAVKEMNVLVKLVGREEDV
                     NRELAKYTYPKEKIEVVHAEEVISTDEVPTMAIRKKKNSSMVVGMQLVKNGEADAFVSA
                     GSTGALLTGSLLIVGRLPGVERPVLGTCLPTKNGFTFLVDSGANVDCKAKYLEQFGKMG
                     SVYVENVFGKKNPSVALVNIGAEKEKGDSLTKEAYELLEVSDLNFVGNIEPRNIPFGEA
                     DVIVCDGFVGNTILKFAEGLSKTLVDIIKSEITKGAYKIAAAMLVKPFRNVKKYFDADE
                     VGGAPFIGLKSLVVKAHGSSNAKAFKNAIRQCVLFKEADIVGKIQDKL"
     CDS             11749..12510
                     /locus_tag="ctg128_12"
                     /transl_table=11
                     /translation="MYQIKNLLENDDIRVLTELGPFTVIEYLRDLSVSPANAATAYFAS
                     EMNVRRRQVICDLKKANITLQAGAMQWMVGNVNATTGIKGVGDLFGKAIRGKATGESAI
                     KPEYTGNGTLVLEPTYKYILLEDVADWNGSLILEDGLFLACDSNLTHKAVMRSNLSSAV
                     AGGEGLFNLGLSGSGVVALECPCPREELIEINLQDDVLKIDGNMAIAWSGSLDFTVERS
                     GKTLIGSAASGEGLVNVFRGTGRVLMAPVLD"
ORIGIN
        1 gacggatgtg attaatccaa aaagagcctc gccagaccaa ttactccctt atcataaaaa
       61 aataagtgca gagggtaaag cacaaatgat atgctttatc tcttacactt atatggtact
      121 aaaaagtgcc ctccataaat cgctcggaca gcactttttc tattccaata tttacttttt
      181 tcttctttct tgcactttta atctataata catctctagt gcttctaaaa ttgttttttc
      241 catagttttt ggggaagtcc ccggagaaaa gtatctttct atcttttcca aaggcacttt
      301 taactgctct ttctgattgc ctttttgctc tgacaatagc tgctctatag taaagaaaca
      361 taatgctgat tcttcttcca actttcgcag ctgaattgcc tgtgcatggc ttggtgtgca
      421 gtcaagttgt cccattactt ccagtaatat tccctgactt tcagaagata agtaagagag
      481 ttccacagca ggacgtagag ctattttttt ctcatcaacc atatctaata ttggttttat
      541 caagtatgtt aaacggatat atcgccgaac ctgatcctga ctttctccca cctgttcacc
      601 aatcaactgc ctggaagttt tcttctgaaa attatgtgcc agtggcacaa cattattctt
      661 tcttggtctg ccaccttttc ttttgatcgc atccattcgc attttatatg caaatgcttt
      721 ttccgatggc aatatgtttt ctctttggat atttgaatca accatcgtaa tgatggcatc
      781 ttcatcactt aactccttga ttatgcaggg aaccttgtat tgttctgcca aaatagaagc
      841 tgcttttctt ctatgccctg ccaccatctg atacttgttg tctactaatc taacaatcaa
      901 gggtaccatg acgccatact ttttgatgct ttcggaaagt tccattaaac tttcatcttc
      961 aattacatgg tatggatggt ctggaaaatc agaaatttca tctacatcca aataatagat
     1021 tttcttattt tcatcattcg taacatatgt gttgtaaaca tttacttctt ccatgacaaa
     1081 cactcctcgt catttatagt aatttacatt ccacatagta catttcgaac taagaattcc
     1141 atatcgtgat aacgcatttt tcgacacgaa tcttggtcac taacctctat tttttattga
     1201 gtgttatttg ctccatttcg tccagcaaaa gactatatat agaataaaat tcaacaaaat
     1261 accctatatt ttgtcccttc tacttccata ttcattctaa ctaacgaaat attctacagc
     1321 attttccggg aaaaattcct tcaattcatt ataaagctgg gctgccaatg ttttattatg
     1381 ggcaatgacc agcgtgggtt tctgtatttt ttcaatgacg tttgccatgg taaaggtttt
     1441 cccggaaccc gttaccccca ccaaagtctg aaatttcaat ccattctgaa atccatcggc
     1501 gattttttcg attgcctgtg gctggtcacc agtaggctga aatttggaat gtattttaaa
     1561 tggtttgtcc atgacacacc tccgtttaca caaatcattc tcatgcagtc aagcctctga
     1621 ctgcaaagca ccatataaac atccattttg tttctatgtg ctcatcgact accaaaaagt
     1681 atatcacagt taaatactaa agtatagggg aacagcgaaa atatacaaac atttgttcta
     1741 ttttttcgtt atggaatatc gtaaaactgt cggatatgct ctgcaatctg catcaactgc
     1801 tcatggtcag caattcgatc tcgtttttcc ttacctttta atataccctc ttttctccat
     1861 tttttcagta cgtaacaaag gctgcggcgg ctgatgccga tttcttcgca aatttcatcc
     1921 agcgtatagc tttgcagtct tgcaggatgc atcagacaat acatcgccgt attttcttct
     1981 gctgtaaaaa gcgtcagact aaagactttc cgatacatct gataggtacg gctgctggta
     2041 ctgcggtaaa attccagggc aaacgccgga ttttccatga gctggcagaa aagctgatct
     2101 ggaaattcca gataaacaca aggagtttcc gcaatgatat tggcatcgaa gctataacca
     2161 cgcatacggc tgatatggcc ggaaaagctg cccacgccaa tttcatccag caaaatacgt
     2221 atgccgcgat aggtcaggct gacaactttc acagacccct gcaaaatata aacaatgcga
     2281 tatccctcat cggctgcatt ggaaatacat gtcttggcag gaacttcatg aatggtgatc
     2341 tgacttgttt ccagataagg tctaatcatg gggtatatat ccaattttcc tacaaaatcc
     2401 tgccagttcg cccagattct ctcatgcata tacaaattct tcctttcata tgtttttgat
     2461 tttgtgaata gtttatcata tttttccaaa tagtgcaaat tgcacttaac gaaagcatgt
     2521 atgcctgcca taataaaacc atcatcattc acagaaaggc aggttgaaaa agtttggaaa
     2581 gtaatgagat gaaattacaa gaaatcctca aagcaagagg tatcactgat gaacagttaa
     2641 aggaagtgca ggagcaggat attcccgctg ccgctgagag cttccagcgt atcatggaca
     2701 tctattatct gctgaaagta accgcagata tggaaagtgc ctactggtac aaccgtgtat
     2761 ggtgggaaaa tgacggcgat ctgttggaag tacgccgttc aaaagccgtt gccgcttctc
     2821 tggcacacag cacacctacc attttgcctt atgaaaaact tgttatgaac aagacaaaac
     2881 atctgcgtgg tgccttcccc ttcccttggg tttgtgcaag cttcttcaat tcccttgcgg
     2941 aatccctcat ggaagaagca gaagcgcctg ctgaaaacga agctgactcc gtttctgttg
     3001 ttggcgccgg cggcggcaac gttacagaaa gctatggcga agtcatctcc attgcaaaaa
     3061 aatttggtat gcggaaagaa aacatccctg ttctggtaaa agtatccaaa tactgggacg
     3121 gcatttccgt agaagatatt tccacaaaat atgcaaaaac acttcccggc tttgaacagt
     3181 tccagaacat catggacagc gttctggtta tgttcgactc cttcgcaatt cctcagggtc
     3241 gtgaagttat gaactattac atgcctttgc agtacggttt tgacggcatt ctggaactgt
     3301 gcgatgaaaa aatcgcaaaa accatgggtg aagctggagg cgacggggtt ctgggcatga
     3361 gccgcggcta ctactatgct gctatgaaag aaatcgtcaa aggtctgagc cagtggtgcg
     3421 aaaactacgc acgcaaagca gaagatctgg cttcttgcga accagatgaa gcatacaaaa
     3481 agaattatct ggaaatcgca caggtaatgc acaacatcgc tcacaaacgt ccttctacat
     3541 tccgtgaagc actgcagatg acactgtgtc tgcatctggg cgttgtaaac gaagaccctc
     3601 agtctggtca gtccatcggt cgtctgggtc aggtattgca gcccttctat gaaaaagaca
     3661 tcgctgacgg caccaccaca gaagaagaag ttgtggaact gctggaactg taccgcatca
     3721 agatcacatg tatcgaatgt tttgcttctg ctggcgtatc cggcggcgtt ctttccagca
     3781 acacattcaa caacctgtct ttgggcggtc agaactacga tggtctgtct gcggttacac
     3841 ctttggaata cctcatcatc gaagcaggta tgcgtgcgca gacacctcag cctacccttt
     3901 ccatccttta cgatgaaaag ctgcctgagg acttcctgat gaaagctgcc gcttgtacca
     3961 aactgggcat gggctatcct gcatggatga acaatcaggt gggcatgaac ttcatgctcc
     4021 gtcagtacgg tcccgaaggt atggatctgt atgatgcccg tgcatggtgt ctgggcggct
     4081 gtctggaatc tgcacccggc tgcttcctgc ctctggaata caacggcaaa gtgaccatga
     4141 tccccggcgg cgcttcccct acttgcggca ccggtatcca cttcacaggt ctgccgaagg
     4201 ttctggaact ggtactgaca aacggcgtgg acaaacgtac cggaaaacag gtattccctc
     4261 ctcataacaa gaaactggaa acatttgatg aactgctgga tcagtggaaa gaatatctgg
     4321 acatcagcaa ccgcattgta aacaaagtca acaacattca gatggacgta tggcgcaaat
     4381 acaacatgcc tgccgtaaac tccctgctga aaccggactg cttcaagaaa ggtcagcaca
     4441 tcggtaactg tggcgctcgt tataacgcct gcatcaactt tgaatcctgc ggtaccatca
     4501 cattcatcaa ctctctggcg tctttgaaga aaaacgtata cgacaccaag aaatatacat
     4561 tggaagaaat gacagatgcg atgctgcata acttcggttt ccgcaccgct tatgacaccg
     4621 gcgtattctc tcccgattat cgcgaaagca cagacgacgc tcagaaatac gctgaaatct
     4681 ttgcagactg catcaacgca ccgaaatacg gcaacgcaga tccttatgca gaccagctgc
     4741 tgcgggatta ccacatgtac ctgctgcatt atctgcctac actggagtcc ttctttggca
     4801 aaccggaata tctctgccag atttccgttt ccacccatgg tcctcagggc ttcatcacac
     4861 tggcaacagc cgatggtcgc ttagcaggca ccacatactc cgacggttcc gtatctgccg
     4921 cccccggcac agacaaaaac ggtgtttatg ccctctttga atctgcaacc gtttacgatc
     4981 attctcagaa ccagaatgca cagatgaacc tgaaactgca tccttcttct gttcagggcg
     5041 tacagggcac cagaaaactg ctggaactgg ttcgtactta tatgcgtaaa ggcggtttcc
     5101 acgtacagtt caacgtggta agctccgaca cattgaaaga agcacagaaa acacctgacc
     5161 agtatcgtga cctgatggtt cgtgtagctg gctttacaca gtactggtgc gaaatcggca
     5221 aacccatcca ggatgaggtt atctatcgta ccgaatatga agaagtttaa gtggaggcgt
     5281 gaaaccatga aacatgtaga atgcattaac tatatcaact tagactgtga gaaaggcatg
     5341 tgtgcccttt ccaaacagat cgttcccatt gatggcaacg gcagcgacgc ctgcggtcat
     5401 ttccaggcag cgcccgtatg cggcaactgt gcatgcttcg cagatgcaga caaacacggc
     5461 atcggcacat gcaaaggctt tgaaaaagaa aactggactt atgcaaaatg tggtgctttc
     5521 tgctgtgagc actacaaagc agcacggggg taagcctatg gatgcacgcg gacatatttt
     5581 cgatattcag tccttttctg tccatgacgg acccggctgc cgcaccacag tatttatgac
     5641 aggctgtcct ttgcagtgcc gttggtgcgc aaacccggaa agctggattt acggcaagca
     5701 tctgatgttt gcccaggcat cctgcaaatg ggacaaaggc tgtgacgtat gtctttctgt
     5761 ctgtcccaca ggtgccatca ccatggagcc aggacagccc cctcaggtag actggaacaa
     5821 atgcaaggac tgccatgact ttccctgcac ctccatctgc cccaaccggg cactgaaaca
     5881 gtgtgtgcgg gaatatacca gcgaggaact cctgcaaatc ctccgcaggg atttcagcag
     5941 ctggggcagc aacggtggcg tcacattcag cggcggcgac cccatcacac agcatgattt
     6001 cctcatagaa gtcctcaagg actgtcataa gctgggcatc catactgcca ttgaaaccag
     6061 cgcacatttc cccagagaaa aatttctgga tgtgatgcag tacatcgact ttgcctttat
     6121 cgatgtaaaa aacatggaca gtgaggcaca caaagccgga acaagcgtag gcaatgaact
     6181 gattctggac aacatccgcg ctctgaaaca aagcggctgg aaaggtcgtc tggtgctgcg
     6241 tcagcctacc atctgcggct acaatgacag cgaagaaaac gcaaaaaaac tcatttcctt
     6301 tatgaaggaa aatgatctct ttgaaatcaa cctgctgaaa ttccatcgtt tgggtcaaac
     6361 caaatgggaa cagctgggca aaacatatga ttatgctact ggcggcgaaa tgacagacga
     6421 agccatgacc gcattgcaga gcctttatct ggatgctgga atcgcctgct acattgggca
     6481 tcatacctct ttctgatgtc cactttccat aaactttcat gccgtaacgc tgcataagca
     6541 gtatacagaa caggcaagtg tctttccaat caaatggacg ggacacttgc ctttctgttt
     6601 tttgtgggtg ggataaagtc ttgtccaaac agctgtacac aacggtatac gtggaaaaga
     6661 cattgttcca tctcctcttt ggaaaacatt tttttccatt tttatagata ctctccaatg
     6721 atttttcatt tccggctttt ttcatggttt ctttttgggc aagatttccc ccaccttttt
     6781 aaatcgtcgt catttttccc gaacattatt tcttttggac tttctttcac cgcaaatttt
     6841 cattggaaat cggtttttat gtgaaatctt ccagtgctgt ttttgttgta ttccatcgtt
     6901 ttttcgtata aaatagaaat gatggcatgc acagcatgcc ttatcaattt tggagcaaca
     6961 agagatacca tcatttttta gaatcataag gaggaaccat catgggcggt ttttttggcg
     7021 taacttccaa gcaggattgc gtacttgata tctttttcgg ggtggactat cattctcatc
     7081 tgggcacacg cagaggcggt atggtcatcc acagccggga aaaaggcttc caacgccaga
     7141 ttcacaacat cgaaaacaca ccttttcgta ccaaatttga aaaagatctg atcgattttc
     7201 agggtcattc cggcatcggc tgcatcagcg actccgatcc tcagcccctt ctggtacgtt
     7261 ctcatctggg cttatatgcc atcacaacag tcggtgtcat caacaacgct gatgagctca
     7321 tcaaaaacta cttctctgac catggacacc agtttatggc aatgagctcc ggcaaagtca
     7381 atgccacaga actcatcgcc gcactgatca accagaaaga cgatctggtt tccggtatcc
     7441 tccatgcaca ggaacagatt gacggttccg caaccattct gattctgaca gaagatgatt
     7501 ccatcatcgc tgccagagat aaaatgggca gactgcctgt tcttatcggc aaagaccacg
     7561 aaggctactg tgtttccttc gaatcctttg cctacaccaa actgggctat gaaaacgtat
     7621 atgaacttgg tccccgtgaa atcgttaaga tcacacctga cggctatgaa acactgaatc
     7681 ctgccggcaa ggatatgaag atctgtgcgt tcctgttcag ctactatggc taccccaact
     7741 ccaactacga aggcatcaat gtcgaagtga tgcgttacaa aaacggggaa atcatggcag
     7801 caaacgaaaa gaaaaacggc acactgcctg atgtagacta cgttgcaggc gtgcctgact
     7861 ccggtatccc ccatgccatt ggttattcca aagaaagcgg caaagctttt gcccgtcctt
     7921 ttgtaaaata tacacccacc tggcctcgtt ctttcatgcc cgccaaccag aaagttcgta
     7981 atcaggtagc aaaaatgaaa cagattcccg ttcccgaact gattgaaggg aaaaagctgc
     8041 tgtttgtgga cgactccatc gttcgtggta cacagctgag agaaactgtt gaattcctct
     8101 atcgttctca cgcagcagag gtacatatgc gttccgcatg tcctcccatc atgtatagct
     8161 gcaaatatct gaatttctcc agcaacggct ccgatatgga tctgctggca cgccgcgtcg
     8221 tacaggaact ggaaggcgac gaaggtcata aacatctgga tgaatacgca gacgcttcca
     8281 cagaaagagg caaatgcatg ctccgctcca tctgtgaaaa actgggcttt gactccctgg
     8341 gttatcagtc cctggatggt ctgctggatg ccatcggcat tgaccgtgac aaagtctgca
     8401 cctattgctg gaacggcaaa ggctgatatt tcatactgtc gcaggaaatc tcctgcggca
     8461 gtttttttct gtttttttcc caatcccttg ttattttctt tctactttgt taccataaaa
     8521 aaatacaact gtcataaagg aggttttttc tatggctgca aaagtatact tttcccgtga
     8581 aatcacaccg gaaaaagtcc tggaattata taaaatggct ggcaaagaac tcactggcaa
     8641 tattgccatc aagcttcact ccggtgaaga aggtaatcag aatttcctga aaccggattt
     8701 ctggaaacct gtcatcgact ttgtaggcgg cactgttgtg gaatgcaata ccgcttatga
     8761 aggcgaacgg aacaccactg aaaaacacaa agcgctgctg actcgtcacg gatgggatgc
     8821 ctacttcaaa gtagacctga tggacgcaga aggccctgat atggtgctgg aaatccctaa
     8881 gggcaaacag attcagaaaa actatgtagg caagcatctt gcagactatg attccatgct
     8941 ggtactctcc cacttcaaag ggcaccccat gggcggctac ggcggcgcat tgaagcagct
     9001 ttccatcggt gtggcatctt ccttcggcaa agcctatatc cacggtgcag gggaaccgga
     9061 aaaaatctgg acagcagatc atgacgcatt tctggaatcc atggcagatg cagcatcttc
     9121 cgttgtggaa tacttcaaag gcaatgtaat ctacgtcaat gttatgaaaa acatgtctgt
     9181 ggactgcgac tgctgtgcag ttgctgaaga cccttgcatg aaggatattg gtattctggt
     9241 atccttagac cctattgcca ttgaccaggc ttgtctggac ttggtttatg ccgctgatga
     9301 ccccggtcgt gaccacctta tcgaacgcat tgaaagccgc aacggtgttc ataccattaa
     9361 agccgctgcc gctttgggct ttggttccag agaatacgat ctggtagaag tataaacatt
     9421 ttctcaaaaa caaaagagcc ggctctttct caagagtgtc cggctctttt ttcacgaaaa
     9481 aagcaggtga ttgaaaaaga atatcctttg caatcacctg ctttcttatt atgctttcat
     9541 tttttccaat gctgcattgg ctgcgttctg ttctgcttct tttttgctct tgccgctgcc
     9601 ctgtcccagc accttgcctt cgtgggtcac ttctgccaca aagactttgt tgtggtcggg
     9661 acccttttca tctacaatgg catagtgtac aggaaccttg ctgattttct ggatgatttc
     9721 ctgcaaatgg gtcttgcagt ccagattacg gaaattggtc tttgtctgag caatctggtc
     9781 ttccataaac cgcataacat atgtagaagc ggcttcgata ccgccatcca tacataccgc
     9841 gccaataatg gcttcaaaag catctgcaag gatagaatct ctgtttctgc cgccggtact
     9901 ttcttcccct ttgcccaaaa acagatttct gcctacaccc aattttctgg acagacctgc
     9961 cagagagcct tcacaaacca ctgccgcccg cagtttggtc agttcccctt ccggcatttc
    10021 cgggaatttg cggtacatat attcacttac caccatgtcc agcactgcat cgcctaaaaa
    10081 ttccagtctt tcgttatttt cgtgactgcc ttttttattt tcattggcat aggaactatg
    10141 ggtcaatgcc agcagcagca aatgcttatc cgcaaaatga tatcccagtt ttttttcaaa
    10201 ttcttccaaa ttcaaataat tcatattact tctccactac tcttctgata taatccaacg
    10261 catccccaat ggttttcata ttctccgccg catcgttgtc aaattcgatg tcataggctt
    10321 cctccaatgc agaaatgatc tggaacaagt ccaaagaatc cgcaccgatg tctttaaagg
    10381 aagtttcctc ccgtaaacta tctgcagaaa tatgcagctg atccgcaatg atctgcatta
    10441 caacagtttc gtccatattt tcaacctcct cttttctttt ctgtcaatac tatactctat
    10501 ttccgacatt ttgtcagcag aaatcctgga aaaacagaag ttttttccca ttttgtacac
    10561 aaaattacac tgcttacagt ttatcctgaa ttttccctac aatgtcagct tctttaaaca
    10621 gcacacactg tctgatggcg tttttgaatg ctttggcatt ggaactgcca tgagccttta
    10681 ccacaagaga tttcagaccg ataaaaggcg caccacctac ttcgtctgca tcgaaatatt
    10741 tttttacatt gcggaaaggt tttaccagca tagccgcagc gattttataa gcgcctttgg
    10801 tgatttcaga cttgatgatg tccaccaatg ttttgctcaa gccttcggcg aatttcaaaa
    10861 tggtattgcc cacaaagccg tcgcagacaa tgacatccgc ttccccaaaa ggaatatttc
    10921 taggctcaat attgcccaca aaattcaaat cagatacttc cagaagctca taagcctctt
    10981 ttgtcaggct atcacctttt tccttttcgg caccaatatt caccagtgca acagaaggat
    11041 ttttcttgcc aaatacgttt tctacataaa cggaacccat tttgccaaac tgttccagat
    11101 attttgcttt acagtctacg tttgcaccgc tgtctaccaa gaaggtaaag ccattcttgg
    11161 taggcaggca agtacccaat acgggacgtt ctacgcccgg cagacgacct acaataagca
    11221 gagagcctgt caggagggca ccagtactgc cggcggaaac aaaggcgtct gcctccccat
    11281 ttttcaccag ctgcataccc acaaccatag aggaattttt ctttttgcga attgccatag
    11341 taggcacttc atcagtgctg atgacttctt ccgcatgcac cacttcgatt ttttcttttg
    11401 gatatgtata ttttgccagt tcccgattga catcttcttc tctgcctacc agttttacca
    11461 gcacgttcat ttctttcact gcgtctactg cacctttgac ggtttccaca ggtgccaagt
    11521 ccccgcccat ggcatccagt gcaacgatta ttttctgatc cataattcac catgatcctt
    11581 tctttcaaat tacatgcttt tagtataaac aattccccat aaaattacaa tcccgcaccc
    11641 caatactttt ttcttagcaa cgaagtcatt gctgtatttt acaaaatatg gtaaagtaac
    11701 attgtatgaa tcataatacc ttttatggat gtaaaggagg cattatttat gtatcagatc
    11761 aaaaatcttt tagaaaatga tgacattcgt gttttgacag aattgggacc ttttaccgtc
    11821 attgaatacc tgcgggattt aagtgtttct cctgcaaatg cagctacggc ttatttcgct
    11881 tctgaaatga atgtgcgcag acgtcaggtc atttgtgatt tgaaaaaagc caatatcaca
    11941 ttacaggcag gtgctatgca gtggatggtt ggcaacgtca atgccaccac aggcatcaaa
    12001 ggcgtaggcg accttttcgg caaagccatc cgcggaaaag caaccggtga atctgccatc
    12061 aaacccgaat atactggcaa tggcactttg gtgctggaac ccacttacaa atacattctg
    12121 ctagaagatg tggcagactg gaacggctct ctgattctgg aagatggtct gtttcttgcc
    12181 tgcgactcca atctgacaca caaagccgtt atgcggtcta atctatcctc tgctgtagcc
    12241 ggcggagagg gtttgttcaa ccttggctta agcggcagcg gcgtggtagc gttggaatgc
    12301 ccttgcccca gagaagaatt gattgaaatc aatcttcaag atgacgtact gaaaatcgac
    12361 gggaatatgg caatcgcatg gagcggcagt ctggacttta ctgtagaacg ctccggcaaa
    12421 acgctcattg gttctgcggc ttccggcgaa ggtctggtaa acgtattccg cggcacaggc
    12481 agagtactga tggcacctgt tctggactaa aaagagaaat acatcctatt accttataag
    12541 aaaacaaata tagctggaat ccttaaagtg aactgaaccc aaaaagttag acaatatttt
    12601 caaattaaaa ttgtttaaga agccagaagg gcttgttgtc tgtaaattgc aggtggcaag
    12661 ccctttaact ttgctttgat tc
//
