LOCUS       c00022_NZ_JMTB..       14463 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JMTB01000022.1 Trabulsiella guamensis ATCC 49490
            GTGU.assembly.022, whole genome shotgun sequence.
ACCESSION   NZ_JMTB01000022
VERSION     NZ_JMTB01000022
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:24:36
            Original ID  :: NZ_JMTB01000022.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14463
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14463
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7623:14283]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7624..14283
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..14463
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14463
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(11..256)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MALVKASLTLFGGDTVVVRCSERCHIHLMSAKHRASETQTDILSV
                     QNRENAFLTVPYSGTWNVLIDSHSQSLEHSISYVAA"
     CDS             complement(505..855)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MQRIVIIANGAAYGSESLFNSLRLAIALREQQALDLKLFLMSDAV
                     TAGLRGQKPAEGYNIQQMLEILTAQNVPVKLCKTCTDGRGITTLPLIDGVEIGTLVELA
                     QWTLAADKVLTF"
     CDS             complement(954..1505)
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MMKPILYTALASTLLWSVASQASELFQLQSPAFADNGLMDKKFAG
                     NNSQNANCTGENISPALVWSNLPAQTQSLVLVVHDPEGAKGLGVTHLVAYNIAPSAAGF
                     AENALRDGKGFTGGKNTPGTDRWYGPCPPPGSGAHHYTFTLIATSLPPSLPAGLTREQL
                     FDKVKGHALAATGLIGRFGQ"
     CDS             1674..3089
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MSLLFRRATPLMLSLLLLAGGVEGASSSFMQQAENPFDNNQDNLP
                     DLGLAPVQDDSARHLAEMAKAFGEASMEDNGLTTDEQAKLFALDKLRTEVSGQVNQQLE
                     TLLSPWGNASVALTVDDNGGFSGSHGNWFVPLQDNNRYLTWSQVGVTQQDDGLVSNAGI
                     GQRWIAGDWLLGYNTFYDHQLDENLARGGFGAEAWGEYLRLSANYYQPFNDWSVRSDTR
                     SERMARGYDLTAQARLPFYQHINTSVSLEQYYGDSVDLFHSGTGYHDPMAVSLGVNYTP
                     VPLVTISALHKQGENGVSQNNLGMKLNYRFGVPLKKQLQSSEVAAAKSLRGSRYDSPER
                     SELPVMEYRQRKTLSVFLATPPWDLQPGEAVQLKLQVRSRHGIRALHWQGDTQVLSLTP
                     PVDSESADGWSIIIPAWDYSEGARYEWHLAVVVEDNKGQRVSSNEITLSSTEPLTVFPD
                     SSSSPAWQSQPLE"
     CDS             complement(3090..3740)
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MSNQERATILLIDDHPMLRTGVKQLISMAPDIQVVGEASNGDQGI
                     ELAESLDPDLILLDLNIPGMNGLETLGKLRERTLSGRVVVFSVSNHEEDVVTALKRGAD
                     GYLLKDMEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATSDRDVSQLTPRERDI
                     LKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     CDS             complement(3733..5529)
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MHKRRFTPLTLVNQLVLIVLLSTLIGATGMTISARLVHGVQGSAH
                     AINKAGSLRMQSYRLLASIPLTAEDQILLDNMEATVFSPELEQAAIRDGQVPQLTALQK
                     YWQGELAPGMKKAHNQETVAGDVARFVNRIDQLVYAFDHTTEERIKSVVSTMRWMVLVM
                     VLLLIFTIVWLRARLMHPWQQLLRMARAVSQRDFTQRARISGRNEMATLGMALNNMSEE
                     LAESYAVLEQRVQEKTARLEQKNEILAFLWQSNRRLHSGIPLCERISPVLNDLQALTLL
                     QDIEVRVYDTEDEENHQEFTCHSETSCDEKGCHLCPRDLPSVSRGGSTLKWRLADAHNQ
                     YGILLATLPTGCHMSHDQQQLVDTLVEQLTSTLALDWHQEKQQQLIVMEERATIARELH
                     DSIAQSLSCMKMQVSCLQMRGEALPQESRDLLAQIRNELNTSWAQLRELLTTFRLQLTE
                     PGLRPALEASCIEYSAHFGFNVQLDYQLPPRYVPSHQAIHVLQIVREALSNALKHAQAT
                     EVKVTVYQQENQVKLVVEDNGCGVPDHAERSNHYGLIIMRDRAQSLRGDCQVRRRDNGG
                     TEVVVTFIPEKSLSLQQGDIYE"
     CDS             5842..7233
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_7"
                     /sec_met_domain="MFS_1 (E-value: 7.2e-17, bitscore: 50.8,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHSSVEEKASSAVITDWRPEDPAFWQQNGHRIASRNLWISVPCL
                     LLAFCVWMLFSAVAVNLNKVGFQFSTDQLFMLTALPALSGALLRVPYAFMVPVFGGRRW
                     TAFSTGIMIVPCVWLGFAVQDPSTPFSIFVIISLLCGFAGANFASSMANISFFFPKQKQ
                     GGALGINGGLGNMGVSVMQLVAPLVVSLSMFAFFGSSGAVQPDGSMLYLENAAWVWVPL
                     LVIFTLAAWFGMNDLAASKASLSEQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLA
                     KTQFPDVQILHYAFFGPFIGALARSTGGAISDRLGGTRVTLVNFVVMAIFCALLFLTLP
                     THGEGGNFLAFFAVFMVLFLTAGLGSASTFQMISLIFRKITMERVKAQGGTEERAMREA
                     ATDTAAALGFISAIGAIGGFFIPKAFGASLDLTGSPAGAMKVFLVFYIACVVITWAVYG
                     RKTKK"
     CDS             7624..11367
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_alph_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="Molybdopterin (E-value: 2.1e-192,
                     bitscore: 629.3, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 7.9e-26,
                     bitscore: 79.9, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_alph_N (E-value: 3.8e-20,
                     bitscore: 61.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKV
                     VRSTHGVNCTGSCSWKIFVKNGLVTWEMQQTDYPRTRPDMPNHEPRGCPRGASYSWYLY
                     SANRLKYPLMRKRLMKMWREAKAQHSDPVNAWASIIEDVDKAKSFKQARGRGGFVRSSW
                     QEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYC
                     DLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAI
                     TPDYAEIAKLCDLWLAPKQGTDAAMAMAMGHVMLREFHLDKPSQYFTDYVRRYTDMPML
                     VMLEARDGYYAPGRTLRAADLVDALGQEKNPEWKTVAMDEAGNMTAPNGSIGFRWGDKG
                     KWNLEQRDGTTGEDIQLRLSLLGSHDDIASVGFPYFGGDGTEHFNSVELENILLHKLPV
                     KRVTLADGSVALVTTVYDLTMANYGLDRGLDDENCATSYDELKAYTPAWAEQITGVPRA
                     QIIRTAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWA
                     HYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETLSAQELLSPLAD
                     KSRYSGNLIDFNVRAERMGWLPSAPQLGTNPLRIAAEAEKAGMTPVDYTVKSLKEGTIR
                     FAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTENGIQGVDLGKQGAAKPE
                     EVEWVDNGLDGKLDLVVTLDFRLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSA
                     AVDPAWESKSDWDIYKDIAKKFSEVCIGHLGQEIDVVTLPIQHDSAAELAQPLDVKDWK
                     KGECDLIPGKTAPHIMVVERDYPATWERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRK
                     LNYTKTDGPAKGQPMLNTAIDAAEMILTLAPETNGHVAVKAWAALSEFTGRDHTHLATN
                     KEEEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQD
                     HQWMRDFGESLLVYRPPIDTRSVKVVMGQKSNGNPEKALNFLTPHQKWGIHSTYSDNLL
                     MLTLSRGGPIVWMSEADAKDLGIEDNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQ
                     ERIVNLPGSEITGQRGGIHNSVTRISPKPTHMIGGYAQLAYGFNYYGTVGSNRDEFVVV
                     RKMKNINWLDGEGNDQVQESVK"
     CDS             11364..12899
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_9"
                     /sec_met_domain="Fer4_11 (E-value: 1.2e-40, bitscore:
                     127.4, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00057, bitscore: 10.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 7.8e-33,
                     bitscore: 101.7, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNVE
                     SKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIEDYYEPF
                     DYDYQNLHTAPESKHQPIARPRSLITGQRMEKITSGPNWEEILGGEFEKRAKDQNFENM
                     QKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMC
                     ITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGMPTVCSESCVGRIRYLGVLLYDADAIEN
                     AASTENEKDLYQRQLEVFLDPNDPQVIAQALEDGIPQSVIDAAQQSPVYKMAMDWKLAL
                     PLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTG
                     PVLRALKRMLAMRHFKRAETVDGVNDTRALEEVGLTEAQAQEMYRYLAIANYEDRFVVP
                     SSHRELARDAFPEKSGCGFSFGDGCHGADTKFNLFNSRRIDAIDVTSKTEPHQ"
     CDS             12896..13606
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="Nitrate_red_del (E-value: 3.8e-16,
                     bitscore: 48.9, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIELVIVARLLEYPDAALWQHQQELFDALASSEKLAKAESQKLAV
                     FLRDLTTQDLLDAQATYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYEQHGLQ
                     LDSRELPDHLPLYLEYLGQLSEREAIGGLQDIAPILALLSARLSQRDSRYAVLFDVLLT
                     LASTDIDSDKVAEKIATEARDDTPQALDAVWEEEQVKFFADQACGESEISAHQRRFAGA
                     VAPQYLEISNGGQH"
     CDS             13606..14283
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="Nitrate_red_gam (E-value: 2.2e-81,
                     bitscore: 262.1, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLTMFFFDIYPYIAGTVFLVGSWLRYDYGQYSWRASSSQILDR
                     KGMNMASNLFHFGILGIFAGHFLGMLTPHWMYEAFLPIDVKQKMAMIAGGACGVMTLVG
                     GLMLLKRRLFSPRVRATTTTADILILSLLMIQCALGLLTIPFSAQHMDGSEMMKLVGWA
                     QSVVTFHGGASAHLEGVAFVFRVHLVLGMTLFVLFPFSRLVHIWSAPVEYLTRKYQIVR
                     ARR"
ORIGIN
        1 gccctgaacg ttatgctgcg acgtagctaa tggagtgttc cagcgactgg ctgtggctgt
       61 cgatcagcac gttccacgta ccactgtagg gtacggtcag gaaagcattc tcgcggtttt
      121 gcacgctcag aatgtctgtt tgtgtttcac tggcgcgatg ctttgcgctc atcaaatgaa
      181 tatggcaacg ctccgagcag cgtaccacca ccgtatcccc accaaataac gtcaaacttg
      241 cttttaccag cgccattttc taccccgttg aataaagcca agtgctccct gcgaccgact
      301 cctgagcgtg atgctgttca catttcgctc tctgcataac accaaagggg gagggtggag
      361 atgatgattt tgatcaaatt ttgcggtaaa gattaaacat taatgacatt ccacctgaaa
      421 ccattcagct gacgactgct ttcggcgaaa aaagcgcgtc agctgaaaat ataatgcgga
      481 aaacagacct gcacgcagca aaaattaaaa tgtcagtacc ttatcagccg ccagagtcca
      541 ctgcgccagt tcaacgagcg tgccgatttc cacaccgtca atcagcggca gcgtggtaat
      601 accacgtccg tcagtacagg ttttgcacag ttttaccggc acattctgcg cggtgaggat
      661 ctccagcatt tgctgaatgt tatagccttc ggcgggcttc tgaccacgca gcccggcggt
      721 gacagcatcc gacatcaaaa acaatttcag atccaatgcc tgctgttcgc gtaacgcgat
      781 agccagacgc aggctgttaa aaagcgattc gctaccgtaa gcagcgccgt tagcgataat
      841 cacaatacgt tgcatgatga ctcctgttca acacagtata aggtcacgca atgctacagc
      901 gccgccaggt tgaagccaaa cgctaagacg ccgcatcatg atctgcgaca ggactactgt
      961 ccgaatcggc ctatcagccc ggtcgcggcc agcgcatgtc ctttgacctt gtcgaacaac
     1021 tgctcacgcg tcagccccgc aggaagagaa ggcggcaacg aggtggctat taatgtaaag
     1081 gtatagtggt gtgcgccgct gcccggcggt ggacagggac cataccagcg atcggtaccg
     1141 ggcgtgtttt tgccgccagt aaaccctttg ccgtcgcgca gggcgttttc ggcaaacccg
     1201 gcggcggaag gggcgatgtt ataggccacc agatgagtta cgccgaggcc tttcgcgcct
     1261 tcagggtcgt gtaccaccag taccaggctt tgcgtttgcg caggcaaatt gctccacacc
     1321 agtgcaggag agatattttc cccggtacag ttcgcgttct ggctgttgtt tccggcgaac
     1381 tttttgtcca tcaggccatt atcggcaaag gcgggggatt gtagctgaaa gagttcactg
     1441 gcctgtgatg caacgctcca cagcagcgtg cttgccagcg cggtgtaaag gatgggtttc
     1501 atcatgcagt ctcattaagg aagttatgga ttaactgtag ttgccgcatc gccagaaagg
     1561 tggaaaaaat cctggaattt ggccggtggt cgaatccggg tgaggatcac gctacactca
     1621 cctttcagtt ttgtccgata acaccgtccc attgcttttt attaactaac gtgatgtctc
     1681 ttttattccg ccgtgccacc ccgttgatgt tatcactcct gctgctggcc ggaggcgttg
     1741 agggtgcgtc gtcgtcattc atgcagcagg cggaaaaccc gttcgataat aaccaggaca
     1801 atctccccga tctcggtctt gcccccgtgc aggatgacag cgccaggcat ctggcggaaa
     1861 tggcgaaagc ctttggcgag gccagtatgg aagataacgg tctgaccacc gacgagcagg
     1921 cgaaattgtt tgctctcgat aaactgcgca cggaagtgag cgggcaggtc aatcaacaac
     1981 tggaaacgct gttgtcgccg tggggcaatg ccagtgtggc gctgacggtg gatgataacg
     2041 gcggctttag tggcagccat ggcaactggt ttgtgccatt acaggataac aaccgttatc
     2101 tgacctggag ccaggtcggc gtcacgcaac aggatgacgg tctggtcagc aacgcaggaa
     2161 tcggccagcg ctggatagcg ggtgactggc tgctgggcta taacaccttt tatgatcacc
     2221 agcttgatga aaatctggcg cggggtggtt ttggcgccga ggcatggggt gagtatttac
     2281 ggctgtcggc caactattat caaccgttca acgactggag tgtgcgtagc gacacccggt
     2341 cggagcggat ggcgcgcggg tatgatctca ccgcccaggc gcgtttaccg ttttatcagc
     2401 acatcaacac cagtgtcagt cttgagcaat attacggaga tagcgtagac ctcttccata
     2461 gcggtaccgg ctaccatgac ccgatggcag tatcgctggg ggtaaattat acgccagtgc
     2521 cgctggtgac catcagcgcg ctgcacaaac agggtgaaaa cggcgtcagt cagaataacc
     2581 tcggcatgaa gcttaactac cgctttggcg tgccgctaaa aaaacaactg cagtccagcg
     2641 aagtggcggc agcgaaatcg ctgcggggca gccggtatga cagcccggag cgcagtgagc
     2701 tcccggtaat ggagtatcgt cagcggaaaa cgttgtcggt ctttctggcg acgccgccgt
     2761 gggatttgca gccgggggaa gcggttcaac tgaagctaca ggtgcgcagc cggcatggta
     2821 tcagggcgct acactggcag ggtgatacgc aggtgttaag cctgacgccg ccggttgaca
     2881 gcgagagcgc cgacggctgg agtattatta ttcctgcctg ggattacagc gaaggggcaa
     2941 gatacgaatg gcatctggcg gtcgtggtgg aagacaataa aggccagcga gtctcatcca
     3001 atgagatcac gctgtcgtcg acagaaccgc tgacggtatt ccccgacagc agcagttcgc
     3061 ccgcatggca atcacagcca ctggaatgat tagaagatgc gctcctggtg aacccagact
     3121 gccgcttcca cgcgagattt cagtttcatt tttttcagca tatgcttcac gtggactttg
     3181 acggtgctct cggtgatgtc gaggcggcgg gcgatcattt tgttaggtag cccctgggcg
     3241 atgagcttga gaatatcgcg ctcgcgcggg gtcaactggc tgacgtcacg gtcggaagtc
     3301 gcgcgattgg cgcgcaggct ggcggcaagc acgggggtca gcgcttcgct taacaccatc
     3361 tcaccagcgg cggcctgttg caacgctttc agtagatctt ctggctccat atctttcagc
     3421 agataaccat ctgctccgcg cttgagggcc gtcaccacat cttcttcatg atttgacaca
     3481 ctgaagacca ccacacgacc tgacaacgtt ctttcgcgca gtttgccgag agtttccagg
     3541 ccattcatac ccggtatgtt aaggtcgagc aggatcagat caggatccag cgactcagca
     3601 agttcaatgc cctgatcgcc attgctggct tcgccaacca cctgaatatc cggcgccatg
     3661 ctaatgagtt gttttactcc agtgcgtagc atcgggtgat cgtctattaa caggatggtt
     3721 gcccgttcct gattactcat agatatctcc ttgttgtaac gagagagatt tttcgggaat
     3781 aaaggtcacg acaacttccg ttccaccgtt gtcgcgccgg cgcacctggc aatcgccacg
     3841 caggctttgc gcacggtccc gcatgatgat taaaccgtaa tggttgctgc gttcggcgtg
     3901 atccggtacg ccgcagccgt tatcttccac gaccagtttt acctgatttt cttgttgata
     3961 gacggtcact tttacttcgg ttgcctgagc atgtttaagc gcattgctca gtgcttcgcg
     4021 cacgatttgc agtacgtgga tcgcctgatg cgacggcaca taacgcggcg gtagctggta
     4081 atccagttgt acgttaaaac caaaatgcgc actgtattcg atgcaactgg cttccagggc
     4141 aggacgaagc cctggctcag tcaattgcag gcggaaggtg gttagcagct cgcgcaactg
     4201 cgcccaggag gtgttcagct cattacggat ttgtgccagc agatcccggc tctcttgcgg
     4261 cagggcctca cccctcatct gcagacaact cacctgcatt ttcatgcagg ataacgactg
     4321 cgctatcgag tcatgcagtt cgcgggcgat ggtggcgcgc tcctccatga cgatcaactg
     4381 ctgctgtttt tcctgatgcc agtccagcgc cagtgtcgag gtcagttgtt cgaccagcgt
     4441 atccaccagt tgctgctgat cgtgactcat atggcagccc gtcgggagcg tcgccagcag
     4501 aatgccgtac tgattatgag catccgccag tcgccacttc agggtactcc ctcctctgga
     4561 gacagaaggg aggtcgcggg ggcagagatg gcagcctttt tcgtcgcagc tggtttcaga
     4621 atggcaggta aattcctgat ggttctcttc gtcttcggtg tcatacacgc gcacttcgat
     4681 gtcctgcagc agtgttaaag cctgcagatc attcagcacc ggggaaatac gctcacagag
     4741 tggaataccg gagtgcaggc ggcgattgga ctgccagaga aacgccagaa tttcgttttt
     4801 ctgctccagt cgcgcggttt tttcctgcac gcgttgttcc agcaccgcat agctttccgc
     4861 cagctcttcg gacatgttat tcagcgccat accgagcgtc gccatttcgt tacgcccgct
     4921 gatgcgcgca cgctgggtaa aatcgcgctg actcactgct cgcgccatgc gcaacagttg
     4981 ttgccaggga tgcatcaacc gggcacgcag ccagacgatg gtaaaaatca gcagcaacac
     5041 catcaccagc accatccagc gcatggtcga cactacactt ttaattcgct cttcggtggt
     5101 atggtcaaag gcgtacacca gttggtcgat gcggttgaca aagcgcgcga cgtcgcctgc
     5161 gacagtctcc tggttgtgcg cttttttcat gcccggtgcc agctcgccct gccagtattt
     5221 ttgcagggcg gtcaattgcg gcacctgacc atcgcgaatg gcggcctgtt ccagctcagg
     5281 gctaaaaacg gtggcttcca tgttatcgag taaaatctgg tcttctgcag tcagcggaat
     5341 ggatgccagc aggcggtaac tctgcatgcg cagcgatcca gccttgttaa tggcatgtgc
     5401 gctgccctga acgccatgga ccagacgggc agaaatcgtc atgcctgtcg caccaatcag
     5461 cgtggatagc aggacgatca gcaccagttg attcaccagc gtgagcggtg taaaacgacg
     5521 tttatgcatt gggcaatctg gctcctgagc cggggattta tcccggactt gcgctattgt
     5581 ccggtatccc ccggagtata cccataccca aaaaggatta cctcttaatt gccgtcagaa
     5641 ggtgactcag gaggagaaac acatcgggta gcatcagcca cgtgaaaatc cacacttttt
     5701 taagagtaat tgtctactca ctaaggatta cagtcatttt ccgcgccttt ctgcgccaac
     5761 ttttcctttg atttatatca acttacctgt caccggaaaa actcaatgtt gcaccgttga
     5821 tattcataat cagaggtgtc tatgagtcac tcttccgtcg aggagaaggc aagcagtgcc
     5881 gtcattactg actggcgtcc tgaagatcct gcattctggc agcagaacgg ccatcgcatt
     5941 gcaagtcgaa atctgtggat ttccgtaccg tgcctgctac tggcattttg cgtatggatg
     6001 ttattcagcg ctgtggcagt taatcttaat aaagtcggct ttcagttttc gactgatcag
     6061 ctgtttatgc tgaccgcact gcctgcgctc tcgggagcat tgctgcgtgt accttatgcg
     6121 tttatggttc cggtgtttgg cggtcgtcgc tggacagcat tcagtaccgg tatcatgatc
     6181 gtgccttgtg tgtggttagg ttttgcggtg caggatccgt ccacaccgtt cagcatcttt
     6241 gtcatcatct ctttgctgtg tggttttgcg ggcgccaact tcgcctccag catggcaaac
     6301 atcagcttct tctttccaaa acagaaacag ggcggcgcgc tggggattaa cggcgggctc
     6361 ggcaacatgg gggtgagcgt gatgcagctg gttgcgccac tggtcgtctc gctgtcgatg
     6421 tttgcttttt ttggcagcag tggcgcagta caaccggacg gctccatgct gtatctggaa
     6481 aacgccgcct gggtctgggt gccgctgctg gtgattttca ctctcgcggc ctggtttggc
     6541 atgaacgatc tggcagcgtc gaaagcatcc ctgagcgaac agctgccggt gcttaaacgt
     6601 gggcatttgt ggatcatgag cctgctgtat ctggcgacct tcggctcgtt catcggtttc
     6661 tctgccggct ttgcgatgct ggcgaaaacg cagttcccgg atgtgcagat cctgcattac
     6721 gcgttcttcg gtccgtttat cggcgcactg gcacgttcaa ccggcggcgc tatctctgac
     6781 cgacttgggg gaacccgcgt cacactggtg aacttcgtcg taatggctat cttctgtgcg
     6841 ctgttgttcc tgacgctgcc gacccacgga gaagggggta atttcctcgc cttcttcgcg
     6901 gtctttatgg tgctgttcct gacggccgga ctagggagcg cgtctacctt tcagatgatc
     6961 tcgctgattt tccgcaagat aaccatggag cgtgtgaaag cgcagggggg tactgaagag
     7021 agagcgatgc gtgaagcggc aaccgacacc gctgccgcgc tgggcttcat ctccgccatt
     7081 ggtgctattg gcggcttctt tatcccgaaa gccttcggtg cctcgctgga tcttaccggt
     7141 tctccggcgg gcgccatgaa agtatttctc gtgttctata ttgcctgtgt ggtaatcacc
     7201 tgggcggtat acgggcgtaa aactaaaaaa taaagtgact tcttgattat cctggcgcgg
     7261 gcaaccgcgc ctttttttat ttgtatttag ttacaacata ctaatcgaga taacaacact
     7321 atcaggtctg tgaccccggt aacacaatgt tctgacaggg aggtgatcta ccccttaata
     7381 cccggacgaa ggttaataaa agcaaactgt aagctgaatg ctcataaaaa caatataaat
     7441 caataaatta agaaataaag caacgtacca ctcagggagt atctttcagt ttcaggcgcg
     7501 ttgttaacac aaaccgcctt gatcgttatc aattccaccc atctttcagg acgttacttt
     7561 cgcagcaact taggcaatgt cgacttatca gagagccgtc aggctcctta caggagaaac
     7621 ccgatgagta aattcctgga ccggtttcgc tacttcaagc agaagggcga aacctttgcc
     7681 gatgggcacg gccagcttct taacaccaac cgggactggg aggatggcta ccgtcagcgc
     7741 tggcagcacg acaaagtggt tcgttccact cacggcgtaa actgcacggg atcctgcagc
     7801 tggaagattt tcgtaaaaaa cggtctggtg acgtgggaaa tgcagcagac tgactatcct
     7861 cgtacccgtc cggacatgcc aaaccatgag ccgcgtggtt gcccgcgtgg tgccagttac
     7921 tcctggtatt tgtacagcgc gaaccgcctg aaatatccgc tgatgcgaaa acgtttgatg
     7981 aaaatgtggc gtgaagcaaa agcacagcac agcgatccgg taaacgcctg ggcctctatc
     8041 atcgaagatg tcgacaaagc caaaagcttc aagcaggcac gtggtcgcgg tggtttcgtg
     8101 cgctcctcct ggcaggaagt gaatgaactg attgccgcgt ctaacgtcta taccgtgaaa
     8161 acctacggcc cggatcgtgt tgcaggcttc tcgccgatcc cggcgatgtc gatggtttct
     8221 tatgcctccg gggcgcgcta cctgtctctg attggtggta cctgcctgag cttctacgac
     8281 tggtactgcg acctgccgcc agcatcaccg cagacatggg gtgaacagac cgacgtgccg
     8341 gaatcagccg actggtacaa ctccagctac atcattgcct ggggctctaa cgtgccgcag
     8401 acccgtaccc cggacgccca cttctttact gaagtgcgct acaaaggcac caaaaccgtg
     8461 gcgattacgc cagactacgc ggaaatcgcc aagctgtgtg atctgtggct ggcgccgaag
     8521 cagggtactg atgccgctat ggcaatggcg atgggccacg tcatgttacg tgaattccat
     8581 ctcgataagc ccagccagta cttcaccgac tacgttcgcc gctacaccga catgccgatg
     8641 ctggtgatgc tggaagcgcg agacggttac tatgcgccgg gccgcacgtt gcgcgcggct
     8701 gatctcgttg atgccctggg ccaggagaaa aatccggagt ggaaaacggt cgccatggat
     8761 gaagccggta atatgaccgc tcccaatggc tccatcggtt tccgctgggg tgataaaggc
     8821 aaatggaacc tcgaacagcg tgatggtacc accggtgaag acatccagct gcgcttaagc
     8881 ctgctcggca gccatgacga tatcgccagc gtcggtttcc cgtatttcgg cggtgacggc
     8941 actgagcact tcaacagcgt cgagctggaa aacatcctgc tacataaact gccagtgaaa
     9001 cgtgtgacgt tagccgacgg ctctgtcgcg ctggtgacca ccgtttatga tctgacgatg
     9061 gctaactatg gcctcgatcg tggtctggat gatgaaaatt gcgcgaccag ttatgacgaa
     9121 ctcaaagcgt atacgcctgc gtgggccgag cagatcactg gcgtgccgcg cgcacaaatt
     9181 atccgcactg cccgtgaatt tgccgataac gcggataaga cacatggtcg ttcgatgatc
     9241 atcgttggtg cgggcctgaa ccactggtat cacctcgata tgaactatcg tgggctaatc
     9301 aacatgctga tcttctgcgg ttgcgtcggt cagagcggcg gcggctgggc gcattacgtc
     9361 ggtcaggaaa aactgcggcc acagacgggc tggcagccgc tggcgtttgc ccttgactgg
     9421 cagcgtccgg cgcgtcacat gaacagtacc tcttatttct ataaccactc cagccagtgg
     9481 cgttatgaga cgttatctgc acaggaatta ctgtcgccac tggcggataa atcccgctac
     9541 agcggaaacc tgatcgactt caacgtgcgt gccgaacgca tgggctggtt gccgtcagca
     9601 ccgcagctcg ggactaaccc gctgcgtatc gcggctgagg ccgagaaagc ggggatgacg
     9661 ccggtggatt acaccgtgaa gtccctgaag gaagggacaa ttcgttttgc cgctgagcaa
     9721 ccggaaaacg gcaaaaacca cccgcgcaac ctgtttatct ggcgctcgaa cctgctgggg
     9781 tcgtccggta aaggccatga atatatgctg aaatacctgc tcggcactga gaacggtatt
     9841 cagggcgttg accttggtaa gcagggcgct gcgaagccgg aagaggtgga gtgggtggat
     9901 aacggactcg acggtaagct ggatctggtg gtgacgctgg acttccgcct gtcgagcact
     9961 tgcctctatt ccgacatcgt gctgccgact gcaacctggt acgaaaaaga cgacatgaat
    10021 acctcggaca tgcatccgtt tattcatccg ttgtccgcag cggtcgaccc agcctgggag
    10081 tcgaagagcg actgggatat ctacaaagac attgcgaaga aattctcgga agtctgcatc
    10141 gggcatctgg gtcaagaaat tgacgtcgtg acgttgccga ttcagcacga ttctgccgct
    10201 gaactggcgc aaccactgga tgtgaaagac tggaagaaag gcgaatgcga cctgatcccg
    10261 ggcaaaactg caccgcacat catggtcgtt gagcgtgatt acccggcgac ctgggagcgc
    10321 tttacctcaa tcggtccgtt gatggagaaa atcggcaacg gcggtaaagg cattgcgtgg
    10381 aacacccaga gcgaaatgga tttgctgcgt aagcttaact acaccaaaac tgacggtccg
    10441 gctaaaggcc agccgatgct caatacggcg attgatgcgg cggaaatgat cctcactctg
    10501 gcaccggaaa ctaatggtca tgtggcggtg aaagcctggg cggcgctgag cgaatttacc
    10561 ggtcgcgacc atacccatct ggcaacgaat aaagaagaag agaaaatccg cttccgcgat
    10621 attcaggcac agccgcgcaa aatcatctcc agcccgacct ggtcaggcct ggaagacgag
    10681 cacgtctcct ataacgccgg ttacaccaac gttcacgagc tgatcccatg gcgcacgctg
    10741 tcgggtcgtc agcagttgta tcaggaccat cagtggatgc gcgactttgg cgaaagcctg
    10801 ctggtgtacc gtccaccgat cgacacccgc tcggtgaaag tggtgatggg tcagaaatcc
    10861 aacggcaacc cagagaaggc gctgaacttc ctgacgccgc accagaagtg ggggatccac
    10921 tccacttaca gcgataacct gctgatgctg acgctgtcac gtggcggacc gatcgtctgg
    10981 atgagcgaag ccgatgcgaa agatctgggg atcgaagata acgactggat cgaagtgttc
    11041 aacagcaacg gcgccttaac cgctcgtgcg gtggtcagcc agcgcgttcc ggccgggatg
    11101 accatgatgt atcacgcaca ggaacgcatc gtgaacctac cgggatcgga aattactggt
    11161 cagcgcggcg ggatccacaa ctcggttacc cgcatcagcc cgaaaccgac ccacatgatc
    11221 ggcggctatg cccaactggc ctacggtttt aactactatg gcaccgtagg atctaaccgc
    11281 gatgagttcg tggtggtacg taaaatgaag aacattaact ggttagacgg cgaaggtaat
    11341 gaccaggtac aggagagcgt aaaatgaaaa ttcgttcaca agtcggcatg gtgctgaatc
    11401 tcgataaatg catcggctgc cacacctgct cagtcacctg taaaaacgtc tggaccagcc
    11461 gtgaaggtat ggaatacgcc tggtttaaca acgtcgaaag taagcctggc gtcggattcc
    11521 ccaatgactg ggaaaaccag gagaaatgga agggcggctg gatccgtaaa atcaatggca
    11581 agctacagcc gcgtatgggc aaccgcgcca tgctgctggg taaaatcttc gccaacccgc
    11641 atctgccagg cattgaggac tattacgagc cgtttgatta cgactatcag aatctgcata
    11701 ccgcgccgga aagcaaacac cagccgatcg ctcgtcctcg ttcgttgatc accggtcaac
    11761 ggatggagaa gataaccagc ggcccgaact gggaagagat tctgggtggc gagttcgaaa
    11821 aacgcgccaa agaccagaac ttcgagaaca tgcagaaggc gatgtacggc cagttcgaaa
    11881 acactttcat gatgtatctg ccgcgcctgt gcgagcactg cctgaacccg gcgtgtgtgg
    11941 cgacctgccc gagcggcgct atctataagc gtgaagaaga cggcattgtg ttgatcgacc
    12001 aggacaagtg ccgcggctgg cgtatgtgca ttactggttg cccatacaaa aaaatctact
    12061 tcaactggaa gagcggtaaa tctgagaagt gcattttctg ctatccgcgt atcgaagcgg
    12121 gtatgccgac cgtctgttct gagagctgtg taggccgtat tcgttacctc ggcgtgctgc
    12181 tgtatgacgc ggatgccatt gaaaacgcgg ccagtactga aaacgagaaa gatctgtatc
    12241 agcgtcagct ggaggtgttc ctcgacccga acgatccgca agtgatcgcc caggcgctgg
    12301 aagacggcat cccgcaaagc gtgattgacg cggcgcagca gtctccggtt tacaaaatgg
    12361 cgatggactg gaagctggcg ttaccgctgc acccggaata ccgcacgttg ccgatggtct
    12421 ggtacgtgcc gccattgtca ccgattcagt ctgccgcaga tgcgggtgaa ctcggcagca
    12481 acggcattct gccggacgtt gaaagtctgc gtattccggt gcaatacctg gcgaatctgt
    12541 tgaccgcagg ggataccggg ccggtactgc gagcgctgaa gcgtatgctg gcgatgcgtc
    12601 atttcaaacg cgcagaaaca gtagatggtg tgaacgatac ccgcgcgctg gaagaggttg
    12661 gtctgacgga agcgcaggcg caagaaatgt accgttatct ggcgatcgcc aattacgaag
    12721 accgttttgt ggtcccgagc agccaccgtg aactggcgcg tgacgcgttc ccggagaaaa
    12781 gcggttgtgg gttcagcttt ggcgatggtt gccacggcgc tgatacaaaa ttcaacctgt
    12841 tcaacagtcg ccgcattgat gccatcgatg tgaccagtaa aacggagccg caccaatgat
    12901 tgaactcgtc atcgtcgcgc gtctgctcga atacccggat gctgccttgt ggcagcatca
    12961 acaggagctt ttcgacgcac tcgcgtcgtc agaaaaactg gcaaaagcgg aatcgcaaaa
    13021 actggccgtt ttcctgcgcg atctcactac tcaggattta ctggatgcac aggcgactta
    13081 cagcgagctg ttcgatcgtg gtcgcgccac gtcgctgctg ctgtttgaac atgttcacgg
    13141 tgaatcccgt gaccggggcc aggcgatggt tgacctgatg gcacagtatg agcagcacgg
    13201 tcttcagctc gacagccgcg agctgccgga ccatctaccg ctctatctgg aatatctggg
    13261 gcaactctct gagcgtgagg ccattggcgg cctgcaggat attgcaccga ttctggcgtt
    13321 attgagtgcg cgtctgagcc agcgcgacag ccgctatgca gtgttgtttg atgtactgct
    13381 gacgctggcc agtaccgaca tcgacagcga taaagtggca gagaaaatcg ccacggaagc
    13441 acgtgacgat accccgcagg cgctggatgc cgtctgggaa gaagaacagg tgaagttctt
    13501 tgccgatcag gcctgtggtg aatctgaaat ctctgcgcac cagcgtcgtt ttgcaggcgc
    13561 cgtcgccccg caatatctgg aaatctctaa cggagggcag cactaatgtc attccttact
    13621 atgttcttct tcgacattta tccctacatc gcgggcacgg tttttctggt gggtagctgg
    13681 ttgcgttatg actatgggca atacagctgg cgcgcctctt ccagccagat actcgaccgc
    13741 aagggcatga acatggcgtc caatctgttt cactttggga tcctggggat tttcgccgga
    13801 catttcctgg ggatgctgac gccgcactgg atgtacgagg cgtttctgcc catcgatgta
    13861 aaacagaaaa tggcgatgat cgcgggcggc gcctgcggcg tgatgacgct ggttggtggt
    13921 ctgatgctac tgaaacgccg attattcagc ccgcgagttc gcgctaccac aacaacggcg
    13981 gatatcctga tcctctctct gctgatgata cagtgcgcgc tgggcctgct gacgatcccg
    14041 ttctcggcgc agcatatgga tggcagcgag atgatgaagc tggtcggctg ggcgcaatcc
    14101 gtggtgacct tccacggggg cgcgtcggcg catcttgaag gtgtggcgtt tgtgttccgc
    14161 gtacatctgg tgctggggat gacgctgttt gtgctgttcc cgttctcgcg actggtgcat
    14221 atctggagtg cgccggttga atatctgaca cgtaaatatc agattgttcg cgcacggcgc
    14281 taacacgcct tgaacgccac tgaaccctgc tccggcgggg tttttttatg gcggtttgcc
    14341 ggatggcggc tacgccttac ccggcctaca attcgtggcg gtgtttttgt agccccggta
    14401 agcgtagcgt caccagggaa aacagggtcg caaagccgga tagaatttat tgagaagtga
    14461 tgg
//
