LOCUS       NZ_AP019823.1          25274 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP019823.1 Leptotrichia hofstadii strain JCM16775 chromosome,
            complete genome.
ACCESSION   NZ_AP019823
VERSION     NZ_AP019823.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:52:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 499405
            Orig. end    :: 524679
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25274
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[509405:514679]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15274
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..25274
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..25274
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     protocluster    1..24392
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[509405:513797]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10001..14392
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             complement(2017..2685)
                     /locus_tag="ctg1_477"
                     /transl_table=11
                     /translation="MKKLLTFLLLTLSIQLFSANYKVVLKKGVTLSQQEITKNNSEIEI
                     AAKRDYDSIKRAASIGMKSMISRMMGEEIQLPAISQKNSLKFQKKMNELYNNMFDYIMD
                     KNKIDVEKIRYVTNDIVEVTLNIKTPDVTTNLQKYSELMNNNFLNEKEMKNLNNFSEDE
                     IFDKIITKMFSSMKQAFQKTDKYASMKTTIYLEKDNGKWGIAELDEKLKNFREIYKSVN
                     "
     CDS             complement(2766..3080)
                     /locus_tag="ctg1_478"
                     /transl_table=11
                     /translation="MEEKIYTCPLELTQKILSKKWTVIILWLLRHGKVRTKDFKNQIKG
                     SNEKMIIEHLNYLIKEKLIEKREYNVYPKKTEYILSEKGKDLLPILELMQSYGEKYYIK
                     "
     CDS             complement(3164..4483)
                     /locus_tag="ctg1_479"
                     /transl_table=11
                     /translation="MKDLTKGNELKTIIYFSLPILIGNLFQQIYNISDTIIVGNFLGKE
                     SLAAVGSSYQINVLIIAVSIGISLGTSILISQYFGAKDMENLKITANTGFIFSIVLSLI
                     VTTLGFLLSNNILILINVLQKLLLKANIYLKIIFIGVVPTFGYNSLTNTLKGVGDSKTP
                     TYILITSVILNIILDIFFVAVLNSGVAGVAIATVISQFISFFLCLFYIKFKYPNLIFKK
                     YYFNLNFNILKEILIIGMPAMLQQVLISLGFIVIQILVNGFGTDCIAAFISASRIDSFA
                     ELPSINLGQALMTFTAQNYGAKKMDRIIKGGKDSLILGISFSIIISIIIFIFPAFFISI
                     FNRNPEVIFIGNQYLRIISAFYVIFCTMQILNGLLLGYGKSLVPLIASITSFCMFQVPL
                     AILLSKTSLGYNGIWIAAPIGWTAGLLIRVWYFIKISKKI"
     CDS             4818..6923
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gln-synt_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_480"
                     /sec_met_domain="Gln-synt_C (E-value: 8.3e-21, bitscore:
                     71.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENAMKSFGENVFRDSNLKKRVSKAVFKEFKASQLGETELSKETA
                     EVIANAIKDWATKRGATHYCHWFQPLNDLTAEKHDSFLEPTENEELIYKFSGKNLIKGE
                     SDASSFPNGGLRSTFEARGYTIWDTSSYPFIRENKNGVTLYIPTAFISFTGEALDKKVP
                     LLRSMKYISGQALRVLRAFGNKTSNHVFNTLGVEQEYFLVKKDMFEARDDLLLTGRTLF
                     GASAPKGQELSDHYYGKIKEKVINFMSDVDVELWKLGIPSKTRHNEVAPNQFEVAPLFS
                     VANLASDQNQIIMETIEKTALRHDLVALLHEKPFAGVNGSGKHNNWSLGTDDGKNLFSP
                     GKDMKSNTQFLIFVAAVIEAVDRYYPMLRYATATATNDHRLGGHEAPPAIISVFLGDEL
                     TTILSNIAYKKDAPVSESSKVNLSVDVLPAFSMDAGDRNRTSPFAFTGNKFEFRMPGSS
                     STPATSAAVINAMVGKVLSEYADKLEKATEKSFPKVANDIIANAYKKHHRIIFNGNGYS
                     EEWAKEAKKRGLTNEVASNTALRKMIDKDVLELTQEIGMLSEQESVARYNAYADRYVTQ
                     LSIESRTLIDIANKNILPSGLKYSNLLADHIEKNSKYGKAFIKEQEEILKDVLANITSL
                     RKEVKSLEKEINRVRNEKDLGKQTDLAKEKLVTGLEALRVPCDNLEKIINKEYWNFPTY
                     TDLLFKL"
     CDS             7082..8044
                     /locus_tag="ctg1_481"
                     /transl_table=11
                     /translation="MIFLKSLGSIFPIIVMIAIGYILKKRHWFHHTFSENVSKLITNVA
                     LPCSIFYSVLKYLNMDALKEVSNRLIFTFASVIIGYVAAFFVIKLVKMREGRRGVFYNA
                     VVNANTIFIGLPLNMALFGEAASKYYLMYYITNTVSIWTLGYMLLAGDSLEGNKDEKSG
                     FNLKKLLSPPLIAFVIAFIVLLSGIKVITPIVETTKYLGSVVTPLALLYIGIVLADAGL
                     HSIRFDLDTNLALLGRFVFSSIVMIVLLKIAGHFVQLNDLEIKTFVIQSAAPVFAALPI
                     LVNETNGDIGYSTNVVTTSTILFILVVPILMSILNIIHI"
     CDS             8344..8883
                     /locus_tag="ctg1_482"
                     /transl_table=11
                     /translation="VKKIIILLVLLVTGISFSDTCKWIKNPNVYVLKEIELINKSRLIG
                     NVYCDVEHDFMTYYVGIDNLEVGLVYNTRERKELTYENIFKILIDFESDIAKLIPRNIP
                     AKDNQKKPRYYTFRLYAYDAAKKDTFMLFKYILDTKKIDGDWKTYYNNEIFSKTGEKML
                     KTLKDSGYSPTEDIMY"
     CDS             8896..9771
                     /locus_tag="ctg1_483"
                     /transl_table=11
                     /translation="MELILEEDIIYKTKINDFGVEPINKRIITTGEKLIYFNKNKFEKE
                     SGGKVKNCEIIKYIKEKNQLFISSMFFVSTPNGKVYKCDGNKKKIVELVFDTNDSIKVM
                     NFITSGRIVYIEKNCLFSYDVDTEELISAKLARTRKNGNYKIFTSGENVIIKFREDHKH
                     INTINIFENKLKKIFEVKTENNHTYSKIVGLQYFAGTEDGEIEIWNILDQELYNSIKIS
                     DRKITYIEEFEGKYFIGLESGELVITDSKFHILKQEKILKERIVKICVIENEIYVMGCE
                     NRIVKYRMVL"
     CDS             10001..10894
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_484"
                     /sec_met_domain="AdoMet_dc (E-value: 3.9e-29, bitscore:
                     98.2, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIDEIGEEVMNELENNKIKLYGFNNLTKTLSFNIYDICYAETER
                     EQKDYIAYIDEQYNSERLTKILIRVAEMIGAQVLNISKQDYEPQGASVNVLIAEERISP
                     ENIDKSCNQGKPFFEEIGIDSQSMKKGNTSQDTDTVHAHLDKSHITVHTFPEYHPDNSI
                     STFRADIDIATCGEISPLNTLNYLIDSFDSDIITIDYRIRGFTRDISGKKFFTDHNITS
                     IQDYIELEKLKIYDAIDVNVYQSNIFHTKMLIKEIELKNYLFNQDVYEIAPKKRLEITD
                     RLRKEMIEIYSGMNIY"
     CDS             11343..12806
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_485"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2.5e-12, bitscore:
                     44.4, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 4.3e-139,
                     bitscore: 460.7, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKNIDKDRQNKTVLFDALKNHLSNRVVRFDVPGHKGGRGNKEFR
                     DFIGLDAMQMDVNSMKPLDNLCHPTSVIKEAQDIAAEAFGAKEAYFMVSGTTGAVQAMI
                     MATCKAGDKIIIPRNVHRSAINALVICGAIPVYINPGLNKKLGISLGMSINDVKKAIQE
                     NPDAKAILVNNPTYYGICSDLKSIVKLAHENDMFVLVDEAHGAHFYFDENLPISAMEAG
                     ADMAAISMHKTGGSLTQSSILLSGERINADYVRQVINLTQTTSASYLLMTSLDVARKNL
                     AINGRELFEKTVKFAEYARNEINKLGGYYAYGKELIDGDSVYDFDTTKLSVYTKDIGLA
                     GIEVYDILRDDYEIQIEFGDLGNILAIISAGDRGLEIERLISSLAEIKRLYSKDSTGMF
                     DHEYINPDVVLPPQKAFYSEKEMIPIKESAGKISGEFVMAYPPGIPILAPGERITEEII
                     NYIEYAKEKGCLLTGTEDMHVEKINVVLE"
     CDS             12879..13409
                     /locus_tag="ctg1_486"
                     /transl_table=11
                     /translation="MADSRFLKFFNYILLVEGSYSNDKNDKGGETKYGITKERARECGY
                     KGSMKDLTKAMAEKIYEEKYYKARKLDQVRNDKVALSIFDFSVNAGRYGIKKAQEAVNK
                     VYGKNVISVDGAVGPMTLKYLNEVNPAKFLMVYHNLQREYYKSLAKNNVTQNDFLAGWL
                     NRVKVKENYLRNV"
     CDS             13550..14392
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_487"
                     /sec_met_domain="Spermine_synth (E-value: 1.6e-58,
                     bitscore: 194.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 9.5e-18,
                     bitscore: 61.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYTEEHTKNVRFSIKIDKQLVSAKSNFQRIDIFESPEFGRFL
                     TLDGFMMLTEKDEFIYHEMITHVPMAVNPKAKKILVIGAGDGGTVRELVKYEHIERIDM
                     VEIDKMVVDLCREYLPKTANKLEDKRVHIYYEDGLKFVRSKANEYDIVIVDSTDPFGPG
                     EDLFTREFYGNCFNALKEDGILVNQHESPYYEADAKATARANKQLRAVFPFATVYQLHI
                     PTYPSGHWLFGFASKKYNPVKDLKADEWNKFGIETKYYNTELHKGAFALPNYVKDLIK"
     CDS             14423..15274
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_488"
                     /sec_met_domain="Arginase (E-value: 2e-77, bitscore: 257.6,
                     seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNKNIHTFIGCDNEYNESKIAIFGAPFDSTTSFRPGTRFASAVM
                     RNESFGIETYSPYQDKDLEDIKVFDGGDLELSFGNSESTLQDIQDETTEILKDGKIPFM
                     IGGEHSVTLGAVRAVAEKYPDLHIIQFDAHTDLRDEYLGQYYSHASVIRRCWDIVGDDR
                     IFQFGIRSGERDEWKFAKEHLHTTKFNFDGLDEVVEKLKGKPVYFTLDLDVLDPSEFPG
                     TGTPEAGGVTFVELHKAIEKISQLNIVGLDMNELSPVYDQSGQSTALACKLLREILLFI
                     YK"
     CDS             15316..17004
                     /locus_tag="ctg1_489"
                     /transl_table=11
                     /translation="MKKKLPIGISDFKKIIDGNYYYFDKTELIKSIIGEPGEVKLFTRP
                     RRFGKTLNMSMIKYFFDIENKNENKKLFENLKISENEYFEKQGTAPVISISFRNYDESS
                     WGNGFEMIKNTISDLYDEFEFVKENLSARKKEKYDSILFNRATEATWKLSLLDLTKYLY
                     EYYGQKVVVLIDEYDQPIIDSYVKGYYQEAISFFKTFYGVVLKDNNYLEMGIMTGILRV
                     AKENIFSGLNNLRVHTILDNRFTEYFGITESEVEQALKDFDLEFELKDVQRWYNGYLFG
                     DIKVYNPWSIINFLNDEKLKSYWVNTSGNELIKLYLKKLKNEIFDDFSKLLNKKSILRR
                     IDENMTFANLEANYEENIWNLFFHSGYLTLAEEVQDDEEQVYLKIPNEEILKMFSKMFI
                     EVYFENYNSFYNMVYSLKNGDIETFKKELRKILLENVGIFDVSGVYKEQFYHGLMLGII
                     LTLKNEYEITSNNFAGKGRYDLLLKPKNLEKRKEGIILELKVVNAMENLSEDKIFEKLE
                     NECDIALQQIEKKEYASVLKNSGVENVLKIGIAFFGKELAVKFDR"
     CDS             17205..19796
                     /locus_tag="ctg1_490"
                     /transl_table=11
                     /translation="MIDKIKELENLENKYKEIGRINSEIESIIANIKNEAGISREKELL
                     EKNERLAKDLKAFHEKIKVREEEIGRLKNSNAVLIEELKEAKKVRRNGEIDKFQNILAQ
                     KMNVELESGVTRRLSNYAEEMKRKVKMLERNLSHEFSDEADSLRDELKKINGKIGNFLE
                     KSNRKTFENKVFLQEESSVFHNKIKEETALKEGEFLFEREKKRFVFEKLIGLKGFNFLG
                     IISIFLGVFLVFRTQFVKILANNYVKSSASYLLGMFFLFAGEKFYQKNKKHFAVGLIGG
                     GIGILYLTTLLSTLYLKLYPMTAGLFISVILTGLVVILSLRYDSQIIGVLSLIGGYLPY
                     GAYILVNRSNVQIYYVLAYSLILQGIVLGVSWKKDWIYSKIFGFVTGVVNMTGLIYYLN
                     HSIHDKITAFFYIVIFTTAYSFIFLNSHKKENRQSNIIDYVFLSLNLIIKFSLIYSLFD
                     KTTPSWLKAVLVGTVGIIYGFFGDRLKDNKVAKIFYIVALGSFILIIPLIVPEKFVVIA
                     WGVETALLYFFYRKYKNKEMRYGTIAIYLVSLVSNLIVREEKYLLAYIQDLMIISFSFV
                     LYFLIKQKSYKKEVRILNGIFKYLIFAYSIFFINKVIFNVVTSFEAINYGKDALFCILV
                     SLFVLRTVTYRVKKLQDSFSLKFLVIIEIIYLLFMNMYNFFLYISGWSWNIQEEKIPIS
                     YLLSLILLIFVNFYLFIVAKNDIHLCFFKKNEKKPLWILEESIYFLCVANIILRIYEHS
                     GVLILGAGLALDIVGLLLCGYLVWKGFRVPNRNVRRIGLGIGIFFVAKSFLWDFLRFDN
                     SYKLIAYFSMGAILIGTSYIYQTALKKLEQEVKESLSDTDFGKGEKNEENK"
     CDS             19780..20952
                     /locus_tag="ctg1_491"
                     /transl_table=11
                     /translation="MKKINKIILFLFLITIVQLFSSQYFKTIKITGKSAYKQFFLTEDI
                     YENSKNNLGDIRIIDKNGKEIPYVIESGKEQEKHSEKIVARAKIDEVLTKKDKMEFIVK
                     FNSDSSLKDIIGNRLELIPSKNFYTEYTLFGSNNGTDWEQITSGEIYKTPDKSNLTIEF
                     SEKRYEFYKIVTPLDKGNIFSEAILKLSNNEAGKLKTVGTKLDYKIEQEGKNTILKIKS
                     KFLPLKNIVLDVNDEFQRNYTVRSGDNFYAEGVISKVGEKSNLMINLENVPKLSEIIVE
                     IQNGDNSPLKINRVTGNYVPDRIVFRATEGEDYKITFGDENLNKPEYDIAEFADSIKER
                     DEVLVGKLEKSEGNNISKSKDYTVYYNIFIVFIVIVLIGFMVKKIAKNKK"
     CDS             20969..21535
                     /locus_tag="ctg1_492"
                     /transl_table=11
                     /translation="MNIVFILIGILVVLVVMGMGIYNKYIRLKNLNEEGWSGIGVYLQK
                     RLDLIPNLVNTVKGYATHEKETLENVVKLRSQMMSIDTKDIDNIEKIQKLENEMTKTLR
                     SIMMLQENYPDLKANENFLRLQSQLTQIETEIQSSRKYYNGTTRDRNTFVETFPNNIIG
                     GFLGFKKAEFFNAVEGAEKVPEVKF"
     CDS             21579..22916
                     /locus_tag="ctg1_493"
                     /transl_table=11
                     /translation="MEISLTQIMILLIMLVTLAIYSYITWKKFGKDSVDEIISVSEPPK
                     EISAMMTAYINSSQKEMSNYLVYIGLLELISKGFVIIEDYVDLKKYNKVKKNSKMTEDE
                     YEIKKDKKTVEIIDIEKYYRQITKKKYAFNMEKVNDYGCRQWELSEEERMILEFLIEYD
                     KDSILGHKKPIMEQFFKILEVLKEKFDGRGNYTFLYLIGIKSIKRERWDKRLYNSNWKF
                     KTFYIVIIFLFGILLFIFEGMKAIVPSIVLFPIFFWVILLSNILFLILKTKAFPILMRL
                     MISLLIGAFCGIMYFWAGLMLFLFGIAGVLITLATILLVLYFRNIGKFTDRGARVKKDL
                     EGFRMYVKSGEVKKFNDVEELISYFKKILPFSQALKVQKHVVEMVKRSIEISGFNDKKE
                     YIENMLNIFIYKNDKFMKSFGNEILTNEILESARNDALGGNYYEEF"
     CDS             22903..23091
                     /locus_tag="ctg1_494"
                     /transl_table=11
                     /translation="MKSFSNRKWKSIFSISFVFFTLFFFNAKSLIAEANQIMKFNDVDE
                     LAEYFKGILCGCFGSQE"
     CDS             23191..25083
                     /locus_tag="ctg1_495"
                     /transl_table=11
                     /translation="MIFQNKKFSILFIFMVMFLFNSSRLDAVILHSEKIRNYEVTVQIN
                     KNGTLTVNEVIDYQFGEEFKHGIYRYIPLRSKRFGFDVHKSFIKMNWIKRDGEDEEYTK
                     NHFYEGIRYRIGSETELVNLYRTESRYELNYDIYNAVFEKDGIYQVYYNAIGQLWNVPI
                     EQASVIIRFPDGQKIKKNEIEKLEVYTGSYGEKGENYDILENDEEIHISTKELEAKNGL
                     TFMLNLKTDKISPTLADKLKIVYLSNPAIIILPFLLLFLTIYSIVTWNLFGRDPQGKSV
                     IPEFNLPKDISPMFAAYINGERDTVEILNAGIFTLLTKGFIVANRVNGEIKYNKEYKTV
                     YTQETELAEEERMLLDALSSEKNNIFGGEKRIYNKANSIIEILKDKYHKIIYKNNGSFL
                     VPFYCAAPVFIIFIFSQTNFEFFNPFIILYILITLGSFFHRIWITVSKKLLTGLIIIAI
                     LGVSFYQGIEIFVFVAYFVILFITYSKLIGKYTNEGLRKKEYLKGMKMYIKTAEENQIR
                     KFDNVKELIEYFNGILPFAVALGVKSEAIKLMKKTIKIYNFDINESYINSRTHMYAYSN
                     HSFTNAFSRSYSSGKSKIMSEKFSSSKSGSGGGGFFSGGGFSGGGSGGGGGGSW"
ORIGIN
        1 gggagaaggg gtgcctgaca tacctgagag gagaagcgcc tcaaggggaa acaggccgca
       61 gtgaagagtc ccaagcaact gtttaccaaa aacacaggtc tatgctaagc tgaaaggcga
      121 cgtatatggg ctgacacctg cccagtgccg gaaggttaag aggaggagtg agagctccga
      181 attgaagccc cggtgaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
      241 gtcgggtaag ttccgacctg cacgaatggt gaaatgattt gggagctgtc ttggctggag
      301 acctggtgaa gttgtaatgc cggtgaagat accggctacc tgcagtagga cggaaagacc
      361 ccgtggagct ttactgcagt ctggcattgg gttttggctg tgtgtgtata ggatagttgg
      421 gagactgtga agctgaggcg tcagtttcag cagagtcgcc gttggaatac caaccatatg
      481 ccgttgaaat tctaatctgg taacggagac agtgctagat gggcagtttg actggggcgg
      541 tcgcctccaa aagagtaacg gaggcgttca aaggttccct caggctggat ggaaatcagc
      601 ctaggagtgc aaacgcataa gggagcttga ctgcaagact gacgggtcga gcaggcacga
      661 aagtgggagt tagtgatccg gcggttccgt atggaaggac cgtcgctcaa cggataaaag
      721 ctaccccggg gataacaggc tgatacttcc caagagtcca tatcgacgga agtgtttggc
      781 acctcgatgt cggctcgtct catcctgggg ctggagaagg tcccaagggt tgggctgttc
      841 gcccattaaa gaggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
      901 cactgcaggc gcctgaatac tgaaaagatc tgaccttagt acgagaggac cgggttggac
      961 agacctctga tgtaccagtt gtcacgccag tggcacggct gggtagtcac gtctgggacg
     1021 gataaccgct gaaagcatct aagcgggaag ccggctttga gatgagtgtt cgcagtatcc
     1081 atggagaaca catggttgat aggccagggg tgcaagcgca gcaatgcgtt cagctgactg
     1141 gtactaatat tacatctgct ttttagtcaa tcttttactg ctactattta tttcccattg
     1201 ccttagctag gcagtttagt ttttaaagtt tggtgatgct agcagcaggg atacacccgg
     1261 tcacatttcg aacccggcag ttaagtctgc ttacgcctac gatacttgga ttcgtcccgg
     1321 gaaaataggc agttgccaaa cttttttctt ttgcgtgtct ccgtagctca gccggttaga
     1381 gcatctgact gttaatcaga gggccgttgg ttcgagtcca accggggacg ccattttttt
     1441 ttgcaaaatt tcataggagt ttaaggcaga gaggcatgaa gcattgtaca gcatgtcaat
     1501 gaacagagct gctgtaaata tgagggcagc aggttgctgt ggggaatatg ggaaacttgg
     1561 gcagggaagg attaaggcgc tcctgccttt ttttgttttc aagaaagtag atttatgttg
     1621 tggaaggttt atccaaaaga atggaaattt ctaaaagaaa aaacaaatgg tagagtaaat
     1681 gttcctagga gtttccagtg tattctaact tgtcgaaaaa gactgagaat tgtaggaaac
     1741 agaagtgtaa atttacccta attaagtggt aattcaggaa agaaaaataa gagttatgca
     1801 taccgtgacg tattccctaa aatattgaaa ttaatgaaac aagggtactt ctcaaaagat
     1861 ttattagtaa caaaaagaat taaattagaa gacatcgtaa atgaaggatt tgaagcactt
     1921 gtaaaagaaa aaagccaagt taagatttta gtatcaccta aataattaat aaaataaagg
     1981 gctatctgaa tatggatagt ccttttatgt tttttattaa tttacagatt tatatatttc
     2041 tctaaagttt tttagttttt catcaagttc agcaattccc cattttccat tatctttttc
     2101 taaataaatt gttgttttca tagaagcata cttatcggtt ttttggaagg cttgtttcat
     2161 tgaactaaac atttttgtta ttattttatc aaagatttcg tcttctgaga aattatttag
     2221 atttttcatt tctttttcgt ttagaaagtt gttattcatt aattctgaat atttttgtaa
     2281 atttgttgtt acatctggcg tttttatatt taatgttact tcaacaatat catttgtaac
     2341 atatcttatc ttctcaacgt caattttgtt tttatccatt atataatcaa acatattatt
     2401 atataattcg ttcatttttt tctgaaattt aagagaattt ttttgactta ttgcgggtaa
     2461 ttgaatttct tcacccatca ttctggaaat catagatttc attccaattg atgctgctcg
     2521 tttaattgaa tcataatccc ttttagccgc aatctcaatt tcactgttat tttttgtaat
     2581 ttcctgctgt gataaagtaa cgcctttctt tagaacaact ttgtaattag ctgagaatag
     2641 ctggattgaa agtgtcagta gtagaaaagt tagtagtttt ttcataggta atcaactcct
     2701 tttataattt tgtttgtgag tttattttaa catatttttt tgtatttttt tagagagtaa
     2761 aaaatttatt taatataata tttttctcca taactttgca taagttccaa aataggcaat
     2821 aaatcttttc ctttttctga gaggatatat tctgtctttt ttgggtaaac attgtattcc
     2881 cgtttttcta taagtttttc tttgattaaa tagtttaaat gctcaataat cattttttcg
     2941 ttgctgcctt ttatttgatt tttgaaatct tttgttctga cttttccgtg tcttaaaagc
     3001 cataatatga tgactgtcca tttttttgat aatatttttt gagttagttc cagcggacaa
     3061 gtgtaaattt tttcttccat ataaattttc ctttcaataa aattatttga aattttaaaa
     3121 aacaccaaat aatcttgatt ttactataat tcttttattt tttctatatt tttttagaaa
     3181 tttttataaa ataccacact cgaattagca gtcctgctgt ccagcctatc ggtgcggcaa
     3241 tccaaattcc gttatagcct aacgatgttt tggaaagtaa aatggctaga ggcacttgaa
     3301 acatacaaaa tgaagtaata gaggctatta gtggaactaa ggattttccg tagcctagta
     3361 gcaatccatt tagtatttgc attgtgcaga aaattacgta aaatgctgaa attatacgta
     3421 aatattgatt tcctataaaa atcacttcgg gatttcggtt aaatattgaa ataaagaatg
     3481 ctggaaaaat aaaaataata attgagatta tgatggaaaa tgagattcct aaaattaggc
     3541 tatcttttcc acctttaatt attctatcca tttttttggc tccataattt tgggctgtaa
     3601 aagtcatcaa cgcctgtcct aaatttatgg atggcaattc tgcgaaggaa tcaattcggg
     3661 aagcagaaat aaaagctgca atacagtctg ttccaaatcc atttacaaga atttgaatga
     3721 caataaatcc taggctgatt aaaacttgct gtaacattgc tggcattcca ataatcagta
     3781 tttcttttaa aatattaaaa tttaagttga aataatattt tttaaaaatt aaatttggat
     3841 atttaaattt tatgtaaaat aagcaaagaa aaaaggaaat aaactgtgaa ataactgttg
     3901 caattgccac tcctgcaact ccagagttta gtactgctac aaaaaatata tctaaaataa
     3961 tatttaaaat tacggaagta attaagatgt aagtcggtgt ttttgaatca cctacacctt
     4021 ttaacgtatt tgtaagagaa ttgtagccaa aagttgggac aactccaata aaaataattt
     4081 ttaaatagat atttgccttc agtaacaatt tttgcagaac attaattaaa attaaaatat
     4141 tatttgacag taaaaaacct aatgttgtaa caataagaga taaaactatg gaaaaaataa
     4201 atcctgtatt tgccgtgatt ttcaaatttt ccatatcttt tgcaccaaaa tattgggaaa
     4261 ttagaatgct tgtccctaat gaaataccta tcgaaacagc tattataagt acattaattt
     4321 gataacttga gcctacagcc gcaaggcttt cctttcctaa aaaatttccc acaatgattg
     4381 tgtctgaaat attgtaaatc tgctgaaata aatttcctat taaaattggc aaagaaaaat
     4441 aaattattgt tttcagttca tttccttttg ttaagtcttt catttttatt ttttctcctt
     4501 gtttttattt atctgcctgt taattgatat tttaacattt atttcatttg atatgaataa
     4561 catacttttt tgtgagtata gtccgttcac ttaaaataga agtaaaaata tataaaaatt
     4621 agatatagcc taaccttctc cttttatttt aaactagaat tatcatatat tttttttata
     4681 aaaataaaaa aagagaatgg ggaaattttt gtttgactta tattttctca cattgtataa
     4741 taaaatatat ttaaaaaaat gaagagtcta aaaatactgc ttcataataa attgatacgg
     4801 aaaagaggtt aaaatttatg gaaaacgcta tgaaaagctt tggagaaaat gtctttaggg
     4861 acagtaattt gaaaaaaaga gtttccaagg ctgtttttaa agagtttaag gcgtcgcaac
     4921 tgggggaaac tgaattgtcg aaagaaactg ctgaagttat tgcaaacgct attaaggact
     4981 gggcgactaa aagaggagct actcactact gtcactggtt tcagccattg aatgacttga
     5041 cagctgaaaa gcatgattca tttttggaac ctactgaaaa tgaggaactt atttacaagt
     5101 tttctggaaa aaatttgata aaaggcgaat ctgatgcatc ttcatttccg aatggaggac
     5161 ttcgtagcac atttgaagca agaggttaca caatctggga tacgagttca tatccattta
     5221 taagagaaaa taaaaatgga gttacattgt atattcccac agcctttatt tcatttactg
     5281 gtgaagcgtt ggataaaaaa gtacctttat taagatcaat gaaatatata agtggacaag
     5341 cattaagagt cttgcgtgct tttggaaata aaacttctaa tcatgtattt aatactttgg
     5401 gagtagagca ggaatatttt cttgtaaaaa aagatatgtt tgaagcaaga gacgatttat
     5461 tgcttacagg aagaacctta ttcggagctt ctgcacctaa aggacaggaa ttaagcgatc
     5521 attattatgg aaaaattaaa gaaaaagtaa taaactttat gagtgatgtt gacgttgaat
     5581 tatggaaatt aggtattcca tcaaaaacaa gacataatga agtggctcca aatcagtttg
     5641 aagtagcacc attattttca gtagcaaact tggcatcaga tcaaaatcag ataataatgg
     5701 aaactattga aaaaacagcg ttaagacacg atttagtagc attgcttcac gaaaaaccgt
     5761 ttgcaggggt aaatggttca gggaaacata ataactggtc actgggaaca gatgatggca
     5821 aaaatctttt cagtcctgga aaagatatga aatcaaacac acaattttta atttttgtag
     5881 ccgcggtaat agaagctgtt gacagatatt acccaatgtt gagatatgcg actgcaactg
     5941 cgacaaatga tcacagactt gggggacatg aagcgccgcc tgcaattatt tcagttttct
     6001 taggtgatga attgacaaca attttaagca atattgcata taaaaaagat gcacctgtgt
     6061 cagaatcatc aaaagtgaat ttgtcagttg atgtgttgcc tgcatttagt atggatgctg
     6121 gagatagaaa cagaacttcg ccatttgcat tcactggaaa taaatttgaa tttagaatgc
     6181 cgggatcaag ttcgacacct gcaacttctg cggctgtaat aaatgctatg gtaggaaaag
     6241 tgctgtctga atatgcagat aaacttgaaa aagcaactga aaaatcattc ccgaaagtgg
     6301 caaatgacat tattgccaat gcgtataaaa aacatcatag aataattttt aatggaaatg
     6361 gatacagcga agaatgggca aaagaagcta aaaaacgtgg acttacaaac gaagtggctt
     6421 caaatacagc acttagaaaa atgatagaca aagatgtgct agaactaact caggaaattg
     6481 gaatgctctc tgaacaggaa tctgtcgcaa gatacaatgc ctatgcagac agatatgtaa
     6541 cacaattaag catagaatca agaacattaa ttgacattgc aaataaaaat atcttgccat
     6601 ctggattaaa atattcaaat ttattagctg atcatattga aaaaaattca aaatacggga
     6661 aagcgttcat aaaggagcag gaagaaattc taaaagatgt gttagcaaat attacaagct
     6721 tgagaaaaga agtaaaatcg cttgaaaaag aaattaatag agtaagaaat gaaaaagatt
     6781 taggaaaaca gacagatttg gcaaaagaaa aattggtaac aggacttgag gcattaagag
     6841 taccttgtga taatttggaa aaaattatta ataaggaata ctggaatttc ccaacttata
     6901 ctgatttact gtttaagtta taatattgat aaaaagtgca gggactttaa cgagtccttg
     6961 ctttgtttgt ttaaaataat atttttgtag tgaattgttg taaaatcaac tttaaatgtt
     7021 atggaattat tagatttgat tttgaaagaa atgggtatag taaagaaagg aaagtttaaa
     7081 aatgattttt ttgaaatcac tgggaagtat tttccctatt attgttatga ttgcgattgg
     7141 atatattttg aaaaaaaggc actggtttca tcacacattt agtgaaaatg tgtcaaaact
     7201 tattacaaat gtggctttgc cttgttcgat attctattca gtcttgaaat atctaaatat
     7261 ggatgctttg aaggaagtgt caaaccgttt gatttttaca tttgcttcag ttattatcgg
     7321 atatgttgca gctttttttg taataaaatt agtgaagatg agagaaggtc gacgtggagt
     7381 cttttataat gcggtagtaa atgcaaatac gatatttatt ggacttccat tgaatatggc
     7441 actttttgga gaagcagctt ccaaatatta tttaatgtat tatattacaa atactgtatc
     7501 aatttggact ttagggtata tgcttttggc aggtgattca ttagaaggca ataaagatga
     7561 aaaaagtgga tttaatctga aaaagttgtt atcgcctcca cttattgctt ttgtaatagc
     7621 ctttattgta cttttgtcag gcataaaagt aataactcca attgtggaaa ctacaaaata
     7681 tcttggaagc gttgtaacac ctcttgcatt actatatatc ggaatagtgc tggcagatgc
     7741 agggcttcac agtattcgtt ttgatttgga tacaaatttg gctttgcttg gaagatttgt
     7801 attttcatca attgtcatga ttgtgttgtt gaaaattgct ggacattttg tgcagttaaa
     7861 tgatttggaa ataaaaacgt ttgtgataca gtcggcagcg ccagtatttg cagcattgcc
     7921 aattttagtt aatgaaacta atggagatat tggatattcc acaaatgtag ttacaacaag
     7981 tacaatttta ttcatattag ttgttccaat tctgatgagc attcttaata taattcatat
     8041 ataaaatttt aaatttggaa aatcattaat ttgattttct tttttacgta aaaacctgat
     8101 ttttaagttt gattttaaag aggttttaat atacggcttg aaattaataa aaaaatatgg
     8161 taaactttta ttaaagagaa tggataacta aaataaaagt gaaaaaaaag ttatataaat
     8221 aattttaaaa tatttttgaa atatcattat aatacaaaac taaatatatt gaaattttat
     8281 tataatttta ttttttataa aatattaaga ttagtgtaat aattatgaaa tttaggagga
     8341 aaagtgaaaa aaataatcat attgcttgtt ttattggtaa caggaatttc tttttcagat
     8401 acctgcaaat ggataaaaaa tccgaatgta tatgtgctga aggaaataga gcttataaat
     8461 aaatcccgtt taataggaaa tgtctattgt gatgtagagc atgactttat gacatattat
     8521 gttggaatag ataatttgga agtagggctt gtatacaaca cgcgtgagag aaaggaactg
     8581 acatacgaaa atattttcaa aatattaatt gattttgaga gtgacattgc aaaactgatt
     8641 cctagaaata ttcctgcaaa ggataatcag aaaaaaccac gatactatac ttttagactc
     8701 tatgcctacg atgcggctaa aaaagatact tttatgctgt ttaagtatat tcttgataca
     8761 aaaaagatag acggggactg gaaaacttac tataataatg aaatattttc aaagacaggc
     8821 gaaaaaatgc taaaaacatt aaaagacagc ggatatagcc ctacggaaga tatcatgtac
     8881 taactgaggg gaaaaatgga attaatttta gaagaagata taatatataa aactaaaatc
     8941 aatgattttg gagttgaacc gattaataag agaattataa caactggaga aaagctgata
     9001 tactttaata aaaataaatt tgaaaaagaa agcggaggaa aagtaaaaaa ttgtgaaatt
     9061 ataaaatata taaaggaaaa aaatcaattg ttcatttcga gcatgttttt tgtttcgact
     9121 ccaaacggaa aagtgtacaa gtgtgacgga aataaaaaga aaatagtcga acttgtattt
     9181 gatacaaatg atagcataaa agtaatgaat ttcataacaa gcggcaggat tgtctatatt
     9241 gaaaaaaatt gcctattttc ctatgatgtt gacacagagg aacttatctc cgcaaaattg
     9301 gcaagaacta gaaaaaatgg aaattataaa attttcacaa gtggagaaaa cgttataatc
     9361 aaatttaggg aagaccataa acatataaat acaataaata tttttgaaaa taaattaaaa
     9421 aaaatatttg aagtaaaaac ggaaaataat cacacttact caaaaatagt tggacttcaa
     9481 tattttgcgg gaacagaaga tggtgaaata gaaatatgga acattctgga tcaggaactt
     9541 tataattcaa taaaaatttc tgacagaaaa ataacgtaca ttgaagaatt tgaagggaaa
     9601 tattttattg gtttggaaag tggagaattg gtaattacag atagtaaatt tcatatttta
     9661 aagcaggaaa agatactgaa ggaaagaatt gtaaaaatct gtgtaattga aaatgagatt
     9721 tatgtgatgg ggtgtgaaaa taggatagtg aagtatagga tggttttata aaaagatatt
     9781 ttatttatta atcacagtta ttaatttagc tgtgattttt ttttaaaatt cattttgcaa
     9841 ttttaattgt aaaaattgtg tataaatgat ataatttggc gaaaaaataa gtcaaaaaaa
     9901 tgaataaaaa tatgtgaaaa ataaataaat ttttacgact atggaaataa cattttaaaa
     9961 agaaatttaa atcatagatt taaaggattt taagtgcaat gtgaaaattg atgaaatagg
    10021 agaggaagtg atgaatgagt tggaaaataa taaaattaag ctgtatggat tcaataattt
    10081 aacaaagaca ttaagtttta atatttatga tatttgctat gcggaaacag agagggagca
    10141 gaaggactat attgcatata ttgacgagca atataattcg gaaaggctta caaaaatact
    10201 tattcgtgtt gcggaaatga taggggcaca agtcttgaat atatcaaagc aggattatga
    10261 gccacaagga gcctctgtaa atgttttaat tgcagaagaa agaataagtc ctgagaatat
    10321 tgataaatct tgtaatcaag gaaagccgtt ctttgaagaa attgggatag atagccagag
    10381 catgaaaaag ggaaatacaa gtcaagacac cgatacggtt cacgctcatt tggataaaag
    10441 ccatataaca gtgcatactt tcccagaata ccatccagat aattcaattt ccacttttag
    10501 agcggatatt gatattgcaa cttgtggaga aatttcgcca ttaaatacat taaactatct
    10561 gatagacagc tttgattcgg atataatcac gattgattac agaatacgtg gatttacaag
    10621 ggatatttca ggaaagaaat tttttacaga tcacaatata acttctattc aagattatat
    10681 tgagctagaa aagttaaaaa tttacgatgc gattgatgta aatgtatatc agtcaaatat
    10741 ttttcataca aaaatgctta taaaggaaat tgagctgaaa aattatcttt tcaatcagga
    10801 tgtctatgaa attgcaccaa aaaaaaggct ggaaattacg gatagactta ggaaggaaat
    10861 gattgaaatt tatagtggaa tgaatattta ttagagtcat tcaataataa attaagtatt
    10921 cagataagtt attttttata attttatgtc attaagttat ttttattaat attcgttctt
    10981 ttatttatat taatgttttt tcttttttat gtgcaaaggg gaacagtcgc catccccttt
    11041 gcaaacccgg ctcgtctaag catttttttg aaataaaaac gaaactcgtt acgtaaaact
    11101 tcgctcaaac agtcgttttc attccaaaaa aatcacgaca attttaagtt taactacaat
    11161 aactaatttg attaaaataa acattgaaga aaaatttcgt taaaaaaata taaataaaat
    11221 aacaaaaact attttaatca aaattttcta aaataaaaat ttataaagct gaatacttaa
    11281 tataaaattt agaaatttaa aattataata aataaaagta aaaatatgta aggagttaaa
    11341 aaatggggaa aaatattgat aaagatagac agaataagac agttcttttt gatgctttaa
    11401 aaaatcatct ttctaacagg gttgtgagat ttgatgtgcc ggggcataaa ggagggcgtg
    11461 gaaataagga gtttcgggat tttatcggac tggatgcgat gcagatggat gttaattcaa
    11521 tgaagccgct tgataattta tgccatccaa cttcagttat taaagaggct caggatatag
    11581 cggcggaggc ttttggggca aaagaggctt attttatggt aagcgggacg actggggctg
    11641 tacaggctat gattatggca acttgcaagg ctggagataa aatcattatt ccaagaaatg
    11701 tgcatagaag cgctattaat gcactggtaa tttgtggagc gataccagtt tatattaatc
    11761 ccggacttaa caagaaattg ggaatatctc ttgggatgtc gattaatgat gtgaaaaagg
    11821 caattcagga aaatcctgat gcaaaagcaa tattagtgaa taatcctact tattacggaa
    11881 tttgttcaga tttgaaatct attgtaaaac tggcacatga aaatgatatg tttgtgctag
    11941 ttgatgaggc acacggagca catttttact ttgatgaaaa tttaccaatt tcagctatgg
    12001 aagctggagc agatatggcg gcaatcagta tgcataagac aggtggttct ttaacacaaa
    12061 gttcaatttt gttaagtggt gagagaataa acgctgatta tgttcggcaa gttataaact
    12121 tgactcaaac tacgagtgca tcgtatttac ttatgacttc acttgatgtg gcaagaaaaa
    12181 atttggcgat aaatggaagg gagctttttg aaaagacagt taaatttgca gaatatgcca
    12241 gaaatgaaat taataaactg ggtggatatt atgcgtatgg gaaagaactg attgatggag
    12301 attcggttta tgactttgat acgacaaaat tatctgtgta tacaaaagat attgggcttg
    12361 ctggaattga agtttatgat attttgcggg atgattatga aattcagatt gaatttggag
    12421 atttgggaaa tattttggcg ataatttcgg cgggagacag aggcttggaa atagaacggc
    12481 taatatcttc acttgcagaa attaaacggc tttactcaaa agactctaca ggaatgtttg
    12541 atcatgaata tataaaccct gacgttgtac ttcctccaca aaaagccttt tattcagaaa
    12601 aggaaatgat tcccataaaa gaaagtgctg gtaaaataag tggtgaattt gttatggctt
    12661 atccaccagg gataccgata ttagcaccag gagagcgaat tactgaggaa atcataaatt
    12721 atattgaata tgcaaaggaa aagggatgtc tattaacagg gactgaggat atgcatgttg
    12781 agaagataaa tgttgtttta gagtgaaaat ttttgacgta agaacgcaga cagtatctgt
    12841 gaaattccaa ttaaaataaa tgaaagaagg aaacaaaaat ggctgacagc agatttttga
    12901 aattttttaa ttatattttg ctagttgaag gaagctactc taatgataag aatgataaag
    12961 gcggggaaac aaaatacggc attactaagg aacgagctag agaatgtgga tacaaaggta
    13021 gcatgaaaga tttaacaaaa gcaatggcag aaaaaattta tgaggaaaaa tattataagg
    13081 ctagaaaatt ggatcaagtg agaaatgata aagtggcact aagcatattt gatttttcag
    13141 taaatgctgg aagatatgga attaaaaagg ctcaagaggc tgtgaacaag gtttatggta
    13201 aaaatgtaat tagtgtagat ggagcggttg gacctatgac attaaaatat ttaaacgaag
    13261 ttaatccagc taaatttttg atggtttatc ataatttaca gcgtgaatat tacaaatctc
    13321 ttgctaaaaa taatgtaact cagaatgatt ttctagctgg atggctgaac agagttaagg
    13381 ttaaggaaaa ttatttgaga aacgtttaat gagtgcaaga aaatagaata aaattataaa
    13441 caatggaaaa tttgaggaat ttataaaaaa gttttaaagt acaaaacatt ggaaataaaa
    13501 ggttagatat taaaaaaata ggtaatacaa attgaaagga gtgtagcaga tggaattatg
    13561 gtacacagaa gaacatacga aaaatgttcg tttttctata aagattgata agcagttagt
    13621 tagtgcaaaa agtaattttc agagaattga tatttttgag tcgccagaat ttgggcgatt
    13681 tttgacattg gatgggttta tgatgctgac agaaaaggat gagtttattt accatgagat
    13741 gataactcac gttcctatgg ctgtaaatcc taaggctaag aaaatattgg taattggtgc
    13801 tggagatgga ggtactgttc gtgaacttgt aaaatatgaa catattgaga gaattgatat
    13861 ggtggaaatt gacaagatgg ttgtcgacct ttgtcgtgaa tatttaccta agacagcgaa
    13921 taagctggag gataagagag ttcatattta ttatgaggat ggattgaaat ttgtacgttc
    13981 caaggcaaat gaatatgata ttgtaattgt ggattcgaca gatccgtttg ggcctggaga
    14041 agatttattt acaagagaat tttatggaaa ctgctttaat gcactaaaag aggatggaat
    14101 tcttgtgaat cagcacgaga gcccatatta tgaggcagat gctaaagcaa cagcaagggc
    14161 aaacaaacaa ttaagggcgg ttttcccatt tgcgacagtt tatcagttgc atataccgac
    14221 atatccatca ggacattggc tatttggatt tgcttcaaaa aaatacaatc ctgtaaagga
    14281 cttgaaagct gatgaatgga ataagtttgg aatagaaacg aaatattata acacggaatt
    14341 gcataaagga gcttttgctt tgccaaatta tgtgaaagat ttaataaaat aatttagaat
    14401 aaaaactaga aggagaattt atatgagaaa taaaaatata catacattta tagggtgtga
    14461 caatgaatac aatgagagca aaattgctat ttttggagcg ccgtttgaca gtacaacttc
    14521 gtttagacca gggactagat ttgcttcagc agttatgaga aatgagagtt ttggaataga
    14581 aacgtatagt ccttatcaag ataaggattt ggaggatatt aaggtttttg atggaggaga
    14641 tttggaactt tcatttggaa attcggaaag tacgttgcag gatattcagg atgaaacgac
    14701 agaaattttg aaggatggga aaattccgtt tatgattggt ggagagcatt ctgttacgtt
    14761 gggagctgtg agagcagttg ctgaaaaata tccagatttg catattatcc agtttgatgc
    14821 acatacagac ttgagagatg agtatttagg gcagtattat tcgcatgctt ctgtaattag
    14881 aagatgttgg gacattgttg gagatgacag aatttttcag tttggaataa gaagtgggga
    14941 aagagatgaa tggaaatttg caaaggaaca tcttcataca acaaaattta attttgatgg
    15001 acttgatgaa gttgtagaaa aattaaaagg gaaacctgtg tattttacat tggatttaga
    15061 tgtacttgat ccatcggaat ttcctggaac tggaacacct gaagctggag gagttacttt
    15121 tgtggaactt cataaggcaa tagaaaaaat ttcgcagtta aatattgttg ggcttgacat
    15181 gaacgaatta tcgcctgtat atgatcagtc tgggcaatct acagcactag cttgcaaact
    15241 gcttagggaa attttgctgt ttatttataa atagtctagt ttggtattga ccaggtaaaa
    15301 agggaggaat gttaaatgaa gaaaaaactg ccaataggaa tatcagattt taaaaaaata
    15361 atagacggaa attactatta ttttgataaa acagaattga taaaaagcat tataggagaa
    15421 cctggcgaag ttaagctgtt tacacgtccg agaagatttg gaaaaacact taatatgtcg
    15481 atgataaaat atttttttga tattgaaaat aaaaatgaaa ataaaaaact gtttgagaat
    15541 ttaaaaattt ctgaaaatga gtattttgaa aagcagggaa ctgctccagt tatttcgatt
    15601 tcatttagga attatgatga aagtagctgg ggaaatgggt ttgagatgat aaaaaataca
    15661 atttcggatt tatatgatga atttgaattt gtaaaggaaa atttaagtgc gagaaaaaaa
    15721 gaaaaatacg attcaatttt atttaacaga gcaacagaag caacatggaa attatccttg
    15781 ctggatttaa caaaatatct atatgaatat tatggacaaa aagtggtagt gctaatagac
    15841 gagtatgatc agccgataat tgattcatac gtgaaaggct attatcaaga agcaattagc
    15901 ttttttaaaa cattttatgg agttgtccta aaggataata attatctgga aatgggaatt
    15961 atgactggga ttttgagagt tgcaaaggaa aatatatttt ctggattgaa taatttaaga
    16021 gttcatacaa ttctggacaa tagatttaca gaatattttg ggattacgga aagtgaagtt
    16081 gagcaggctt taaaggattt tgatttagaa tttgaactta aagatgtcca acgatggtac
    16141 aatggatatt tgtttggaga tataaaagtt tacaatccgt ggtcgattat taattttctg
    16201 aatgatgaaa aattaaagtc gtactgggta aatacgagtg gaaatgaatt gataaaatta
    16261 tatttaaaaa aactcaaaaa tgagattttt gatgattttt caaaactttt gaataaaaaa
    16321 tccattttaa gaagaataga tgagaatatg acttttgcaa acttggaagc aaattatgaa
    16381 gaaaatatat ggaatttgtt ttttcacagc ggttatttga cattggcaga agaagttcaa
    16441 gatgatgagg aacaagttta tttgaaaatt ccgaatgaag aaatattaaa aatgttttca
    16501 aaaatgttta tagaagtata ttttgagaat tataacagct tttataatat ggtgtattcc
    16561 ttgaaaaatg gagatattga aacttttaag aaggaattaa gaaaaatttt attggaaaac
    16621 gtgggaatat tcgatgtaag cggagtttat aaagagcaat tttatcatgg cttaatgctt
    16681 ggaataattt tgactttgaa aaatgagtat gaaataactt caaataattt tgccgggaaa
    16741 ggcagatatg atttgctttt gaagcctaaa aatctggaaa aaagaaaaga agggattatt
    16801 ttggaattga aggttgtaaa tgcaatggaa aatttgagtg aagataaaat ttttgaaaaa
    16861 ttagagaatg agtgtgatat tgcattacag cagattgaaa agaaagaata tgcttctgta
    16921 ttaaaaaatt ctggagttga gaatgtattg aaaattggga tagcattttt tggaaaagaa
    16981 ttagcagtta aatttgatag ataaattcaa tttatattga accttgttta aataagaatt
    17041 tgttacgaac ttttctaaca aaagatataa accaatattc ttataatagt tgaaaattta
    17101 ttaaatattc actatttaaa tatggaatag tataaaatta taaattattt tgtaaattaa
    17161 aaatatattt ataaaaaatt tgtgagtttt gaggtggttt tacaatgatt gacaaaataa
    17221 aggaattgga aaatcttgag aataagtata aggaaattgg gagaataaat tcggagatag
    17281 aatcaataat tgcaaatata aaaaatgagg ctggaataag cagggaaaag gaacttttgg
    17341 aaaagaatga aagattggcg aaagatttaa aggcatttca tgaaaagata aaagttaggg
    17401 aagaggaaat tggaaggctt aaaaatagta atgcagtgct tattgaggaa ttgaaggaag
    17461 cgaaaaaggt taggagaaat ggtgagattg ataagtttca gaatattttg gcgcagaaga
    17521 tgaatgtgga attggaaagt ggagtgacta gaaggctttc taattatgca gaggaaatga
    17581 agagaaaagt caaaatgctg gaaagaaatc tttctcacga attttcagat gaagctgatt
    17641 ctttaagaga tgaactcaaa aaaattaatg gaaaaattgg taatttttta gagaaaagta
    17701 ataggaaaac ttttgaaaat aaggtatttc ttcaagagga atcttcggtg tttcataata
    17761 agataaaaga agaaacagct ttgaaggaag gggaatttct ttttgaaaga gagaaaaaaa
    17821 gatttgtatt tgaaaaactt attggtttga agggttttaa ctttttaggg ataatatcaa
    17881 tctttttggg agtttttttg gtatttcgga cacagtttgt aaaaattctg gcaaataatt
    17941 atgtaaaaag ttcagcttca tatttgctag ggatgttttt tctttttgct ggagaaaaat
    18001 tttatcagaa aaataagaag cattttgcag ttgggctgat tggtggtgga attgggattc
    18061 tttatttgac tacacttctt tccacgcttt atctcaaact ttatccaatg acagcgggtc
    18121 tttttatatc agtaatactg acagggctag ttgtgattct ttcgttgcga tatgatagcc
    18181 agataattgg agtattgtcg ctgattggtg gatatttacc ttatggagct tatattttgg
    18241 tgaataggag caacgttcag atttattatg ttttggcata ttctttgatt ttgcagggaa
    18301 ttgtgcttgg ggtttcttgg aaaaaggact ggatatacag caagattttt ggatttgtta
    18361 caggtgtagt gaatatgacg gggctgattt attacttaaa tcacagtatt catgataaga
    18421 ttacggcatt tttctacatc gtaattttca caacagcata cagtttcatt ttcctaaatt
    18481 ctcacaaaaa agaaaatcgt caaagcaaca taatcgacta tgtatttcta agtttaaatc
    18541 taattataaa attttcattg atttacagcc tgtttgacaa gacaacacca agctggctaa
    18601 aagccgtatt agtcggaaca gtcggaataa tttacggatt ttttggtgac aggctaaagg
    18661 acaacaaagt tgcaaaaata ttttatatcg tggcattagg aagttttatc ctaattatcc
    18721 cgttaattgt accagaaaaa tttgttgtga ttgcatgggg tgttgaaact gcactattgt
    18781 atttctttta tagaaaatat aaaaataagg aaatgcgata tgggacaatt gcgatttatc
    18841 tagtttcgct ggtaagtaat ttaattgtgc gggaagaaaa atatttactt gcgtatattc
    18901 aggatttgat gataatatct ttttcatttg tgctttattt cctgataaaa caaaagagtt
    18961 ataaaaagga agttaggatt ttaaatggaa tatttaaata tctgattttt gcgtattcaa
    19021 tattttttat aaataaagtt atttttaatg ttgtcacttc atttgaagcg ataaattatg
    19081 gtaaagatgc attattttgt atattagttt cactgtttgt tttaagaaca gtaacgtata
    19141 gagtaaagaa attacaggat agttttagct tgaaattttt agtaataatt gaaataattt
    19201 atttgttatt tatgaatatg tacaactttt tcttatatat ttctggttgg agctggaata
    19261 tacaagaaga gaaaattcca ataagttatc tgctatcttt aattttatta atttttgtaa
    19321 atttttattt gtttattgtg gctaaaaatg atattcattt atgctttttc aagaaaaatg
    19381 agaaaaagcc gttgtggata ctggaagaat caatatattt cctttgtgta gcaaatatta
    19441 ttttacggat atatgaacat tcaggtgtat taattttagg agctggacta gctttggata
    19501 tagttggtct gctattgtgc ggatatttag tctggaaagg atttagagtg ccaaatagaa
    19561 atgttagaag aattgggctt ggaataggaa tattttttgt ggcaaaaagt ttcctttggg
    19621 atttcttacg atttgataat tcctataaat tgattgctta ctttagtatg ggggctattc
    19681 tgattggaac ttcctatatt tatcagacag ctttgaagaa attggagcag gaagtgaaag
    19741 agagtttgag tgacacggat tttgggaaag gtgagaaaaa tgaagaaaat aaataaaata
    19801 atattgtttt tatttttaat aacaattgtt caactttttt ccagccagta ttttaaaact
    19861 ataaaaataa caggaaagtc ggcatacaag caattttttc taacagagga tatttatgag
    19921 aacagtaaaa ataatcttgg agatatacgg ataattgata aaaatgggaa agaaattcct
    19981 tatgttattg aatctggaaa agagcaggaa aagcacagcg aaaaaattgt agcaagggca
    20041 aaaatagatg aagtattgac gaaaaaggat aaaatggaat ttattgtgaa atttaattct
    20101 gacagttcgt taaaggatat aattggaaac aggcttgagc tgattccttc caaaaatttt
    20161 tacaccgaat atactttgtt tggaagtaat aacggtacag actgggaaca gataacttcg
    20221 ggagaaattt ataagacacc tgataagtca aacttgacaa tcgaattttc agaaaaaaga
    20281 tatgaatttt ataaaattgt aacgccgtta gataaaggaa atatctttag tgaagcaatt
    20341 ttgaaattgt caaataatga ggctggaaaa cttaaaactg tagggacaaa attggattat
    20401 aaaattgagc aggaaggaaa aaatacaatt ctgaaaatca agagcaagtt tttgccatta
    20461 aaaaatattg ttctagatgt aaatgatgag tttcagagaa attatactgt gagaagcgga
    20521 gataattttt atgcggaagg ggtaatttct aaagttggag aaaagtcaaa tttgatgata
    20581 aatttagaaa atgttccgaa attgtctgaa ataatcgttg aaatacagaa tggagataat
    20641 tcaccgctca aaataaatag agtaacagga aactatgttc cggacagaat tgtgtttagg
    20701 gctacagaag gggaagatta taaaataacc tttggagatg agaacttgaa taagcctgag
    20761 tacgatattg cagaatttgc tgattcaata aaggaacggg atgaagtttt ggtaggaaaa
    20821 ttggaaaaat cagagggaaa taatatctca aaatcaaaag attacacggt ttattataat
    20881 atttttatag tatttatcgt aatagtcttg attggattta tggtaaaaaa aatagccaaa
    20941 aataaaaaat agaagaggag aatgaattat gaatattgta tttattttaa taggaatttt
    21001 ggtagttttg gttgtaatgg ggatgggaat ttataataag tatattagac tgaaaaatct
    21061 gaatgaggaa ggttggagcg gaataggtgt ttatttgcaa aaaagactgg atttgatacc
    21121 aaatcttgtg aatactgtta aagggtatgc gacgcatgaa aaggaaacgc tggaaaatgt
    21181 ggtaaaattg agaagtcaga tgatgtcaat tgatacaaag gatattgata atattgaaaa
    21241 gattcagaaa cttgaaaatg aaatgacaaa aacattaaga tcaataatga tgttacagga
    21301 aaattatcca gacttgaagg caaatgaaaa ttttttgaga ttgcagtcac aactgactca
    21361 aatagaaaca gaaattcaaa gttcaagaaa atattataat ggcacaacaa gggacagaaa
    21421 tactttcgtg gaaactttcc caaataatat aataggtgga tttttaggat ttaaaaaagc
    21481 tgagttcttt aatgctgtag aaggagcgga aaaagttcca gaagttaaat tttaatttgt
    21541 ttaaagttta gtaaaattat cataaaggaa ataattttat ggaaataagt ttgactcaaa
    21601 taatgatttt attgataatg ttagtaacat tggcgattta tagctatatt acgtggaaaa
    21661 aatttgggaa ggattctgtc gatgaaatta tttcggtatc agagccacct aaagaaattt
    21721 cagcaatgat gactgcttat ataaatagtt ctcagaaaga aatgtcaaat tatctggtat
    21781 atattggatt gctggagttg ataagcaaag gatttgtaat aattgaagat tatgttgact
    21841 tgaaaaaata taataaagtt aagaaaaatt caaaaatgac agaagatgaa tacgaaataa
    21901 aaaaagataa aaaaactgtt gaaattattg acattgaaaa atattataga cagataacca
    21961 agaagaaata tgcattcaat atggaaaaag tcaatgatta tgggtgcagg cagtgggaac
    22021 tttcggaaga ggagagaatg attctggaat ttttaattga atatgataag gacagtattc
    22081 tcgggcataa aaagcctatt atggagcaat tttttaaaat tcttgaagtt ttgaaggaaa
    22141 agtttgatgg gagaggaaac tacactttct tgtatttaat tggaataaag tctataaaaa
    22201 gggaaagatg ggataaaagg ctttataatt caaattggaa gtttaaaaca ttttacatag
    22261 ttataatatt tttgtttgga attttacttt ttatttttga aggaatgaaa gcgattgttc
    22321 catcaattgt tctttttcca atatttttct gggtaatact tttgtcaaat atactttttt
    22381 taattttaaa aactaaagca ttcccaatat tgatgagatt aatgatttct cttttaatag
    22441 gagcattctg tggtattatg tatttttggg caggacttat gttatttctt tttggaatag
    22501 caggagttct cataaccttg gcaacaattt tacttgtact ttattttagg aatattggaa
    22561 agtttacaga tagaggagct agggtaaaaa aggacttgga aggatttagg atgtacgtaa
    22621 aaagcgggga agttaaaaaa tttaatgatg tagaagagtt gatttcatat tttaaaaaga
    22681 ttttaccatt ttcacaagct ttgaaagtgc aaaaacatgt tgtagaaatg gtgaaaagat
    22741 ctatagaaat atcaggattt aatgataaaa aggaatatat tgaaaatatg cttaatatat
    22801 ttatttataa aaatgataaa tttatgaaat cgtttgggaa tgagatattg acaaacgaga
    22861 tattagaaag tgctcgtaat gatgcattgg gaggaaatta ctatgaagag ttttagcaat
    22921 cgaaaatgga agagtatttt ttcaataagt tttgtatttt tcacattgtt tttttttaat
    22981 gcaaaatcat taattgctga agcaaaccag attatgaaat ttaacgatgt agatgagctt
    23041 gcggaatatt tcaaaggtat tttatgcggt tgctttggga gtcaagaata aagctataaa
    23101 attgttagag aatatgataa aggtgtataa tttttaaagt ttactattga aagagtttga
    23161 gaataactaa aaaataagga tagataagat atgatatttc aaaataaaaa attttcaata
    23221 ttatttatat tcatggtaat gtttttattt aattcaagca ggcttgatgc agtaatattg
    23281 catagtgaaa aaataagaaa ttatgaagtt acagtgcaaa ttaataaaaa tggcacgctg
    23341 actgtaaatg aagtgattga ttaccagttt ggcgaagagt ttaagcacgg gatttataga
    23401 tatattcctt tgcgttcaaa aaggtttgga tttgatgttc ataagtcttt tatcaaaatg
    23461 aattggataa agagagacgg agaggatgaa gaatacacaa aaaatcattt ttatgaagga
    23521 ataaggtaca gaataggttc cgaaacagaa cttgtaaatt tgtataggac tgagagcaga
    23581 tatgagctga attacgatat ttataatgcc gtgtttgaaa aagatggaat ttatcaagtg
    23641 tattacaatg ctattggaca gctttggaat gttcctattg aacaggcaag tgttattata
    23701 agatttcctg atgggcaaaa aattaaaaaa aatgaaattg aaaagttgga agtttatact
    23761 ggaagttatg gagaaaaagg tgaaaattat gacattttag aaaatgatga ggaaatacac
    23821 atttcaacaa aagagctgga ggccaaaaac gggcttacat ttatgctaaa tttgaaaacg
    23881 gataaaataa gtccaacttt agcagataag ctaaaaattg tatatctttc caatccagca
    23941 ataataattt tgccattttt attgttattt ttaacaatat attctattgt aacatggaat
    24001 ctttttggaa gagatccgca aggaaaatct gtaattccag aatttaattt gccaaaagac
    24061 atttctccaa tgtttgcggc atatataaat ggtgaaagag acacagtgga aatattaaat
    24121 gcaggaatat ttacattact tacaaaaggg tttatagtag caaatagagt taatggtgaa
    24181 attaaatata acaaggaata caaaactgtg tatacacagg aaactgagct ggctgaagag
    24241 gaaaggatgc tgcttgatgc tctttcttca gaaaagaata atatttttgg tggtgaaaaa
    24301 agaatttata ataaggcaaa tagtattatt gaaatcctga aggataagta tcataaaata
    24361 atttataaaa ataatggaag ttttttagtt ccgttttatt gtgcagctcc tgtttttata
    24421 atttttatat tttcacagac aaattttgag tttttcaatc cttttataat attgtatata
    24481 cttataacat taggctcatt ttttcataga atttggataa ctgttagtaa aaaattgtta
    24541 acagggctaa taattatagc gattttaggt gtatcttttt atcagggaat tgagattttt
    24601 gtttttgtag catattttgt aatactattt attacgtatt caaagttaat tgggaaatat
    24661 acaaatgaag gcttgagaaa aaaagaatac ctgaaaggta tgaaaatgta tataaaaaca
    24721 gcagaagaga atcagataag aaaatttgac aatgtaaagg aattaatcga atattttaat
    24781 ggaatcttgc cttttgcagt agcgcttgga gtaaaaagcg aggcaataaa attaatgaaa
    24841 aaaacaataa aaatatacaa cttcgacata aatgaatctt atataaatag ccgcactcat
    24901 atgtacgctt atagtaatca tagttttacg aacgcatttt caagaagtta tagcagtgga
    24961 aaatcgaaaa ttatgagtga aaaatttagt tcatccaaga gtggctcagg cggaggcggc
    25021 ttctttagtg ggggaggctt ctctggcgga ggttccggtg ggggaggtgg aggaagctgg
    25081 tagaaatact ggcttttttt cttgttgtaa agtattgttt tttagtttat aatattggta
    25141 taaatattat ttttttaaat ttgtgcaaga atacagataa atccaacaga atacaaaaaa
    25201 tgaaagagat gaaatatgaa aagatacgat ttgaaattta aggagcctat taatgaataa
    25261 atcttatatg gtta
//
