LOCUS       NZ_CP071093.1          24697 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP071093.1 Fusobacterium vincentii strain THCT14A3 chromosome,
            complete genome.
ACCESSION   NZ_CP071093
VERSION     NZ_CP071093.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:51:42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1672249
            Orig. end    :: 1696946
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24697
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1682249:1686946]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14697
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
     cand_cluster    1..24697
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="chemical_hybrid"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..24697
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /region_number="7"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N, Succ_CoA_lig])
                     and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     protocluster    1..23570
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1682249:1685819](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10001..13570
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
     CDS             complement(227..979)
                     /locus_tag="ctg1_1541"
                     /transl_table=11
                     /translation="MKKLTITMLHILPNRVRLKLSAPIKDTKSFYSNIKNNLKYLEMKY
                     NRRLKTITLNFSPNEIFLQEIIYRTAISFSIENGLLPVKLIEENPYKSISPLSMYALAS
                     ILVSSLNGLINKNDTKLQNSMNMFSMGLTVGSVFEHAYVEIKKRGMFDIEIFPALYLLK
                     SFFTEQKLSLVLIMWLTTFGRHLTISHNMTKLVKVFRMKTEKGYQYTATIVDDNSIENF
                     SDFIHHIFFRKHSNYCQFNEKYVTLSKY"
     CDS             complement(992..2998)
                     /locus_tag="ctg1_1542"
                     /transl_table=11
                     /translation="LSDQNLINLIQNTLNSHIFEICKNEKIEKSSKYVIERKLQEESPK
                     EIVKKIIATAGLLGYNLFFKSKSTVALTGIRKFLNYNTLSTLALAMPVLKNGINSLIKN
                     KRPNADTLSSSAIISSILLGKESAALTIMFLEEVSELLTVYTMEKTRGAIKDMLSVGEN
                     YVWKEISEDNVKRVPIEEIKKDDIIVVQTGEKISVDGKIIRGEALIDQSSITGEYMPIK
                     KSVEDDVYAGTIVKNGNISIIAEKVGDDRTVSRIIKLVEDANSNKADIQNYADTFSAQL
                     IPLNFILAGIVYASTRSLTKAMSMLVIDYSCGIRLSTAVAFSAAINTAAKNGILVKGSN
                     FIEELSKAETVIFDKTGTITEGKPKVQSIEIFDNSISENEIIGLAGAAEEQSSHPLATS
                     IMSEIKDRGIEIPKHNKIKTVVSRGVETKIGKGKEAVTIRVGSKKYMLENNIDLTLAIE
                     AERGIISRSEIGLYVAQDEKIIGLIGVSDPPRENIKKAINRLRNYGVDDIVLLTGDLRQ
                     QAETIASRMSMDSYESELLPEDKAKNILKFQSKGSNVIMIGDGVNDAPALSYANVGVAL
                     GGTRTDVAMEAADITITQDNPLLVPGVIGLSKSTVKTIKENFAMVIGLNTFALVLGATG
                     ILAPIYASVLHNSTTILVVMNSLKLLKYDIKTN"
     CDS             complement(3071..3199)
                     /locus_tag="ctg1_1543"
                     /transl_table=11
                     /translation="MKNDNLLTCEIVHRLRGRIRIKSKAFKYVGNSLKLEIEKHLL"
     CDS             complement(3196..3588)
                     /locus_tag="ctg1_1544"
                     /transl_table=11
                     /translation="MFKNILKKTYLMFNKVKVVHSIPGRIRLLIPSLDKFPEQMKKHES
                     YITAIIKLKNGINSIEYSYLTSKILIEYDKTKLKEQDIVDWLNKIWKIIVDNEEVYQGM
                     SVDEVDKNVKKFYEMLKSELEGRINQ"
     CDS             complement(3598..4095)
                     /locus_tag="ctg1_1545"
                     /transl_table=11
                     /translation="MENKMLLPNFYGIFEVKSATKNRIRVEIDKLKNNNEEIESLKENL
                     RKIAVIKNFKIIKTLGSLTVEFDNSQIDTQFMIGIILKLLNLDKELLKDRKGKIKNTFS
                     SLGKLADITIYNKTKGLFDTKTLIATGLLVYGIKKFKNEMLLPSGATLIWWSYRLLTKN
                     GN"
     CDS             complement(4219..4971)
                     /locus_tag="ctg1_1546"
                     /transl_table=11
                     /translation="MKKIITILMLILSTLSFATKKLYVGTNAEFKPYEYLENNKMVGFD
                     IELMELLGKELGYEIKWQDMSFDGLLPALQMKKIDAVIAGMSATPEREKAVSFSIPYIF
                     FEGGHDVIVNDKSSFKKKEDLKRKTVGVQLGSIQEEFAKDNGSIPKLYNNFTEALLDLQ
                     NQKIDAVIIAEVSGKEYLKTMKGIKKIDTIKDKLPNASIAFRKADAKLAKEFSNTILKI
                     KNNPEYAKLVKKYFPEHYDNFITNLKKK"
     CDS             complement(4987..6165)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1547"
                     /sec_met_domain="Peptidase_M20 (E-value: 3e-07, bitscore:
                     27.2, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNRKEILSELFDKYRNELKDLNEYLYNNPELGMQEYKACTAHIN
                     ILKKYGFEIEKGFANLETAYKASYKKVNGARIAILAEYDALPEIGHGCGHNAYGVTSIA
                     SGILVKELMQKLDLQGEILIIGTPAEETNGAKVDMAKLGIFNDIDVAMSVHPCGETHFR
                     SGKSHAMEALQFTFKGKTAHAAASPHKGINALDGVLNLFNSINALRQQILPSARIHGII
                     SKGGEAANIIPDLAIANFYVRAETLDYLRELVERVKNCAKGAALASGTKLEITNYETSF
                     ANLVTNKKLMELYEKNLKTLGVTDIKDREGFGSTDMGDVSQCCPTIHPNFPLTTKHLVG
                     HTVEFATATIQEETYKGMKEACLAMALSCLDIFEKPEILKEIKEEFYQTFKK"
     CDS             6577..7308
                     /locus_tag="ctg1_1548"
                     /transl_table=11
                     /translation="MDNKKDEKILELVNILKNTKYLVFFGGAGTSTDSGVKDFRGKNGL
                     YKTLYKDRYRPEEVLSSDFFYSHRDIFMEYVEKELNINGLKPNKGHIALVELEKMGILK
                     AVITQNIDDLHQVSGNKNVLELHGSLKRWYCLGCGRTGDRNFSCECGGIVRPDVTLYGE
                     SLNQAIVNEAIYQLEQADTLIVAGTSLTVYPAAYYLRYFRGKNLVIINDMDTQYDGEAS
                     LVIKDNFSYVMNKVVEELKKF"
     CDS             7596..8600
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1549"
                     /sec_met_domain="PTA_PTB (E-value: 1.6e-120, bitscore:
                     399.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLGQVRKKALQANRRIVLPESSDERVIRAASQILKEGLAQVIL
                     VGNQEAIMHSAKAYEVSLSGAKIVDPYNFERFNDYVNKLVELRAKKGMTPEEAKKLLLN
                     NPTFFGAMLIKMGDADGMVSGSSSPTANVLRAAIQVIGTQPGVKTVSSVFIMELSQFKD
                     LFGSILVFGDCSVIPVPTSEQLADIATSAAETAVKIAGINPRVALMTFSTKGSAKHECV
                     DRVIEAGRILRERKVKFRFDDELQADAALVKSVGEIKAPLSDVSGNANVLIFPSLSAGN
                     IGYKLVQRLAGANAYGPIIQGLNAPVNDLSRGCSVEDIVVLTAITSAQACIDC"
     CDS             8658..9854
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1550"
                     /sec_met_domain="Acetate_kinase (E-value: 2.7e-149,
                     bitscore: 493.9, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILVINCGSSSLKYQLINPETEEVFAKGLCERIGIDGSKMEYEV
                     IAKDFEKKLETPMPSHKEALELVISHLTDKEIGVIASVDEVDAIGHRVVHGGEEFAQSV
                     LVNEAVLKAIEVNNDLAPLHNPANLMGIRTCMELMPGKKNVAVFDTAFHQTMKPEAFIY
                     PLPYEDYKELKVRKYGFHGTSHLYVSGIMREIMGNPEHSKIIVCHLGNGASITAVKDGK
                     SVDTSMGLTPLQGLMMGTRCGDIDPAAVLFVKNKRGLTDAQMDERMNKKSGILGLFGKS
                     SDCRDMENAVKEGDERAVLAESVSMHRLRSYIGAYAAVMGGVDAICFTGGIGENSSMTR
                     EKALEGLEFLGVELDKEINSVRKKGNVKLSKESSKVLVYKIPTNEELVIARDTFRLAK"
     CDS             10001..13570
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1551"
                     /sec_met_domain="PFOR_II (E-value: 1.1e-15, bitscore: 54.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5e-80, bitscore: 265.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.4e-32, bitscore: 108.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-13, bitscore:
                     47.9, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.5e-09, bitscore: 35.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.3e-07, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0018, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.7e-20, bitscore: 68.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKMQTMDGNQAAAYASYAFTEVAGIYPITPSSPMAEYTDEWAA
                     KGMKNIFGVPVKLVEMQSEGGAAGTVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGEL
                     LPGVIHVSARSLSAQALSIFGDHQDVYAARQTGFAMLATNSVQEVMDLGGVAHLSALKS
                     RVPFLHFFDGFRTSHEIQKVEVMDYEDLKKLVDWKALEGFRKRALNPEHPVTRGTAQND
                     DIYFQAREVQNKFYDAVPDIVASYMKEISKITGREYKPFNYYGAPDAERIIVAMGSVCE
                     AAQEVIDYLVEKGEKVGLISVHLFRPFSSKYFFDVLPKTVKRISVLDRTKEPGSLGEPL
                     LLDIKALFYSKENAPLIVGGRYGLSSKDTTPAQIKAVFDNLAKDTPKDAFTVGIVDDVT
                     HTSLEVGPAMALADPTTKACLFYGLGADGTVGANKNSIKIIGDKTDLYAQGYFAYDSKK
                     SGGVTRSHLRFGKKPIRSTYLVSRPTFVACSVPAYLHQYDMTSGIKEGGKFLLNCVWTK
                     EEAIKNIPNNVKRDLAKNKARLFIINATALAQEIGLGQRTNTIMQAAFFKLAEIIPFEE
                     AQQYMKDYAKKSYAKKGDEIVQLNYNAIDRGANDIVEIEVDPAWANLEVTPLNEPKETA
                     GCGGCCQPDTEFVKKIVRPVNAIKGYDLPVSAFLGYEDGTFENGTSAFEKRGVAVDVPI
                     WNVDKCIQCNQCSYVCPHAAIRPFLINEDELKAAPNSFATKKAAGKGLDGLVYRIQVSA
                     LDCVGCGSCANVCPANALDMRPIAESLETHEDINTNYLYNNVEYRSDLMALDTVKGSQF
                     SQPLFEFHGACPGCGETPYIKLITQLYGDRMMVANATGCSSIYSGSAPATPYTTNKNGE
                     GPSWASSLFEDNAEYGFGMHVGVEALRSRIQHTMEENMDKVDEDIATLFKDWIANRQYS
                     VRTREVRDILVPKLEALNTDFAKEILDLKQYLVKKSQWIIGGDGWAYDIGYGGLDHVLA
                     SNEDINVLVMDTEVYSNTGGQASKATPTGAVAKFAAAGKPVKKKDLAAIAMSYGHIYVA
                     QVSMGANQQQFIKAVKEAEAHQGPSIIIAYSPCINHGIKKGMSKSQTEMKLATECGYWP
                     IFRYNPSLEKIGKNPLQIDSKEPKWEKYEEYLTGEVRYQTLAKSNPEEAKILFETNKKD
                     AQKRWRQYKRMAALDYSEEKEAE"
     CDS             13741..14697
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1552"
                     /sec_met_domain="Ldh_1_C (E-value: 4.8e-25, bitscore: 85.2,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ldh_1_N (E-value: 4.2e-26, bitscore: 88.6,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQTRKVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAH
                     AIDCMDTISFLPHRAIIRDGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFV
                     PDVVKAGFNGIFVTITNPVDIVTYFVRELSGFPKNRVIGTGTGLDSARLKRILSEVTNI
                     DSQVIQAYMLGEHGDTQVANFSSATIQGVPFLDYMKTHPEQFKGVELSVLEKQVVRTAW
                     DIISGKNCTEFGIGCTCSNLVKAIFHNERRVLPCSAYLDGEYGHSGFYTGVPAIIGSNG
                     VEEILELPLDEREIKGFEDACAVMKKYIEVGKSYKIV"
     CDS             14718..15938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 67.1; E-value: 4.5e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1553"
                     /sec_met_domain="MFS_1 (E-value: 1.4e-19, bitscore: 67.1,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQSKESNIKLLLLGRAVSLFGNTIYLIVLPLYILNITQNLKTTGI
                     FFASINLPTIIISPLIGTLIEKFNKKNIILICDVLTSMLYFILFIYFKNSNSLIFLLIV
                     SLILNIISKFFEIASKVLFSEINTPETLEKYNGLQSFLENAVMIFGPVIGTYLFATFTF
                     NFVLIIISLAYFLSFLQELFIKYEKNTNLSKEKSSFFKDFKEGINYIKSKKIIFNFFIL
                     AMFLNFFIANNDEIINPGILIKKYQISEKLFGFSVACYGLGSVVAGIFIYYNNKFKFLK
                     KLKPLFILNSSLMCLGGLLSIILFKYNHYIYFTIFIFFQFLIGMITTFVNVPLISSFQK
                     NVEIEYQSRFFSILSFFSNGLGPLGVLYAGYLSSYIGADVTYIIDNVAIIIIVFLVFNN
                     IKEAVVN"
     CDS             complement(16040..17059)
                     /locus_tag="ctg1_1554"
                     /transl_table=11
                     /translation="MIARTNEGKIDYKKIIIESGLYLVLFCMLVAIIIKEPTFLSIRNF
                     KNILTQSSVRTIIALGVAGLIVTQGTDLSAGRQVGLSAVISGTLLQSMTNVNKAFPKLG
                     EFSIFTTILIVVVVGVVIASINGIVVATLNVHPFIATMGTMTIVYGINSLYYDKAGAAP
                     ISGFVEKYSKFAQGYIQIGSYTIPYLIIYAAIATLIMWTLWNKTKFGKNVFAVGGNPEA
                     AKVSGVNVVLTLMGIYALSGAYYAFGGFLEAGRIGSATNNLGFMYEMDAIAACVIGGVS
                     FYGGVGRISGVITGVIILTIINYGLTYTGVSPYWQYIIKGIIIVTAVAFDSIKYAKKK"
     CDS             complement(17082..18584)
                     /locus_tag="ctg1_1555"
                     /transl_table=11
                     /translation="MENLKYVLEMENISKEFPGVKALDDVQLKLKPGTVHALMGENGAG
                     KSTLMKCLFGIYEKNSGKILLDGVEVNFKSTKEALENGVSMVHQELNQVLQRNVLDNIW
                     LGRYPMKGFFVDEKKMYNDTINIFKDLDIKVDPKKKVADLPIAERQMIEIAKAVSYKSK
                     VIVMDEPTSSLTEKEVEHLFRIIKKLKESGVGIIYISHKMEEIKMISDEITILRDGKWI
                     STNDVSKISTDQIISMMVGRDLTERFPKKDNKAKEMILQVKNLTALNQPSIQDVSFELY
                     KGEILGIAGLVGSKRTEIVETIFGMRPKEHGEILLHGKSVKNKSPEDAIKNGFALVTEE
                     RRSTGIFSMLDVAFNSVISNLDRYKNKFKLLKNKDIEKDTKWIVDSMRVKTPSYSTKIG
                     SLSGGNQQKVIIGRWLLTEPEVLMLDEPTRGIDVLAKYEIYQLMIDLAKKDKGIIMISS
                     EMPELLGVTDRILVMSNGRVAGIVKTSETNQEEIMELSAKYL"
     CDS             complement(18674..19699)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1556"
                     /sec_met_domain="Peripla_BP_1 (E-value: 5.4e-08, bitscore:
                     29.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGMLLGSIILASALVACGEKKEEAKTDAPTGEKLSIGLTAYK
                     FDDNFIALFRKAFEAEAMAKADTVEVTAIDSQNSVATEKEQIEAVLEKGVKAFAINLVD
                     ASAADGIINLLKEKNIPVVFYNRKPSDEAIASYDKLYYVGIDPNAQGIAQGELIEKLWK
                     ENPDLDLNKDGIIQYVMLTGEPGHPDAVARTKYSISTLNDHGIKTEELHKDTAMWDTAT
                     AKDKMDAWLSGPNGSKIEVVICNNDGMALGAIESMKAAGKVLPTFGVDALPEALVKIEA
                     GEMAGTVLNDAKGQASATFNMVVNLAEGKEPTEGTDLKLDNKVILIPSIGIDKSNVADF
                     K"
     CDS             complement(19894..20841)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 240.2; E-value: 1.1e-73)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1557"
                     /sec_met_domain="ROK (E-value: 3.4e-72, bitscore: 240.2,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHYIGIDLGGTNTKIGVVDSEGNLINSKIIKTHSHQNVDKTLER
                     IWETAKKLILEKEIPLFSVVGIGIGIPGPVKNQSTVGFFANFDWERNLNLKEKMEKLSG
                     IETRIENDANIIAQGEAIFGAAKGKKSSITIAIGTGIGGGIFYNGNLISGMSGVGGEIG
                     HMKVVKDGKTCGCGQNGCFEAYASASSLVKEAQERLKLNEENLLFKEINGNLAELEAKN
                     IFDAARKGDEFSKDLIEYESDYLALGIGNLLNIINPECIVISGGISLAGDEILLPIKEK
                     LKKYTMPPALENLEIKVGVLGNEAGIKGAVALFI"
     CDS             complement(20864..21787)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1558"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-30, bitscore:
                     102.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIYDVVIVGAGPAGLTAGIYAGRGNLSTLILEKEGIGSMIMSH
                     QIDNYPGFHIGASGKEIYDTMKKQALDFGCEIKPATVLGFDPYDEIKIVKTDAGNFKTK
                     YIIIATGLGKIGAKKVKGESKFLGAGVSYCATCDGAFTKGRVVSLVGKGDEIIEEALFL
                     TRYAKEVNIFLTSDDLDCNEELKEAVLSKENVKITKKVKLLEIKGEEFVTELDLEIDGN
                     KETVSTNFVFLYLGTKNNIELYGEFVNLSEAGYIITDETMKTRTDKMYAIGDIREKEVR
                     QVATATNDGVIATTFILKEILKSKKK"
     CDS             complement(21810..22433)
                     /locus_tag="ctg1_1559"
                     /transl_table=11
                     /translation="LRVKCFHLGAYGTNCFLAYDENNIAYFFDCGGRNLKQVYEYIEEH
                     KLNLKYIILTHGHGDHIEGLNDLASHYPEAKVYIGEEDKDFLYNSELSLSDAIFGEVFR
                     FKGELITVKEGDTIGDFKVIDTPGHTIGSKSFYDEKDKILMSGDTLFRRSYGRYDLPTG
                     SLEMLCHSLEKLSKLPDETVVYNGHTDNTTIGEERRFLERVGIL"
     CDS             complement(22635..23429)
                     /locus_tag="ctg1_1560"
                     /transl_table=11
                     /translation="MAEKTQKIGIFDSGLGGTTVLKEMIKSLPNEDYIYYGDNGNFPYG
                     SGKTKNELQKLTERILDFFVKNNCKLVIVACNTASTAAIDYLREKFSLPIIGIVEAGVK
                     IASKNTKNKNIAVISTKFTADSHGYKNKAKMLDSELNVKEIACIEFAQMIESGWDTFDN
                     RKELLNKYLSEIPKNTDTLVLGCTHYPLIRKDIEKNIKIKVVDPAVEIVERATQTLSSL
                     NLLNDKKEKGRIIFFVTGETYHFKPTAEKFLGKEIEIYRIPK"
     CDS             complement(23565..24605)
                     /locus_tag="ctg1_1561"
                     /transl_table=11
                     /translation="MKRELALEFARVTEAAALAAYKWVGRGKKESADQAGVDAMRTMLN
                     RLAIDGEIVIGEGEIDEAPMLYIGEKVGQIYNEEEKDSVTYVDPVDIAVDPVEGTRMTA
                     QGQPNAITVLAVGKKGSFLKAPDMYMEKLIVGPEAKGKIDLSKPLEDNIHAVAKALNKE
                     LKDLMIVVLDKPRHKELIKDLQAMGIKVYALPDGDVAGSILTCMIDSDVDMLYGVGGAP
                     EGVISAAVIRALGGDMQARLKLRSEVKGATLENDKISKFEKLRCEEQGLKVGEILKLDD
                     LAKDDEIIFSATGITGGDLLEGVKRKGNIARTQTLVVRGLSKTIRYINSIHNLDFKDEK
                     ITHLVK"
ORIGIN
        1 gatttaatat taattccttg ttttcttaaa aattcatcaa ccttagcttg atttttctta
       61 tatagataaa aagctactgc tgcgactcca actcctactg ctgcacctac taaatgattt
      121 tttgttattc cgtttccaaa catttttaaa cctcctaaat ttatttttta ttataattat
      181 tatattaata aaatgagtaa gttacattct tagtaacaaa tcatttttaa tatttactta
      241 aagttacata tttttcatta aattgacaat aattactatg ttttctaaaa aatatatgat
      301 gaataaaatc tgaaaaattt tctattgaat tatcatctac aatagttgca gtgtattgat
      361 aacctttttc agttttcatt ctaaaaacct ttacaagttt tgtcatatta tgtgatattg
      421 ttaagtgtct gccaaatgtt gttaaccaca taataagtac caaacttaac ttttgctctg
      481 tgaaaaatga ttttaaaaga tacagagctg ggaagatttc gatatcaaac attcctcgtt
      541 ttttaatttc tacataagca tgttcaaaca ctgaaccaac agttaatccc attgaaaaca
      601 tattcataga attttgcaat tttgtatcat ttttatttat taatccattt aaagaagaaa
      661 ctaatattga cgctaatgca tacatagaca atggagaaat tgatttataa ggattttctt
      721 ctattaattt cacaggtagt aagccatttt ctattgaaaa tgaaattgca gttctatata
      781 tgatttcttg taaaaatatt tcatttggag aaaaatttaa agttatagtc tttaatcttc
      841 tattatattt catttccaaa tattttaaat tatttttaat atttgaataa aaactttttg
      901 tatcttttat aggagcagat aattttagcc taactctatt tggtaatata tgaagcattg
      961 taatagttaa ctttttcatt ttatctcctc tctaattagt cttaatatca tattttaata
     1021 attttaatga attcataaca acaagaatag ttgttgaatt atgtaaaact gatgcataaa
     1081 ttggtgctaa tattccagtt gctcctagta caagagcaaa agtattaagt cctattacca
     1141 tagcaaaatt ttcttttata gttttaactg tgctttttga aagtccgata acacctggaa
     1201 ctaaaagggg attatcttgt gtaatagtta tatcagctgc ttccatagca acatcagttc
     1261 ttgtgcctcc taatgctact ccaacattcg cataagatag ggcaggagca tcatttacac
     1321 catcacctat cataattaca ttagagcctt ttgattgaaa ttttaaaata ttttttgcct
     1381 tatcttctgg taataattct gattcataac tatccattga cattcttgaa gcaatagttt
     1441 ctgcttgttg tcttagatca cctgtcaata gaactatatc atcaacacca taatttctaa
     1501 gtctatttat agctttttta atattttctc ttggtgggtc agaaactcca ataagtccta
     1561 taattttttc atcttgtgct acataaagac ctatttcact ccttgaaata atacctcttt
     1621 cagcttctat tgctaatgtc aagtcaatat tattttcaag catatatttc ttacttccaa
     1681 cccttatagt tacagcttcc ttgcctttac caatttttgt ttcaactcca cggctaacaa
     1741 cagttttgat tttattatgt tttggaattt caattcctct atctttaatt tctgacatta
     1801 ttgaagtagc caatggatga gaagattgtt cttctgctgc tccagcaagt cctattattt
     1861 cattttcaga tatactatta tcaaaaattt ctatactttg tacttttggt ttaccctcag
     1921 tgatagtacc tgttttatca aatattactg tttctgcctt agacaattct tcaataaagt
     1981 tactgccttt aactaaaata ccatttttag cagcagtatt tattgcagct gagaaagcca
     2041 cagctgttga aagtctaata ccacaagaat aatcaataac tagcatactc atagcttttg
     2101 taaggcttct tgtacttgca tagactatac ctgctaagat aaaattcaat ggtataagtt
     2161 gagcagagaa agtatcagca tagttttgta tatcagcttt attagagttt gcatcttcaa
     2221 caagttttat aattcttgaa acagttctgt catctccaac tttttctgca attatactaa
     2281 tattaccatt ttttacaata gtacctgcat agacatcatc ttctactgat ttttttattg
     2341 gcatatactc accagtgatt gaagattggt ctattaatgc ttctcctctt attatctttc
     2401 catcaacact tattttttct cctgtttgta caactatgat atcatctttc ttaatttctt
     2461 ctattggaac tctttttaca ttatcttctg aaatctcttt ccaaacataa ttttctccaa
     2521 cacttaacat atctttaatt gcaccacgag ttttttccat agtgtaaact gttaaaagct
     2581 cagaaacttc ttctaggaac attatagtca gtgctgcact ttcttttcca agaagtatgc
     2641 tactgattat tgcacttgaa cttaaagtat ctgcattagg tcttttattt ttaataagtg
     2701 aatttatacc attctttaaa acaggcatag caagagccaa tgttgacaag gtattataat
     2761 ttaaaaattt tctaattcct gtaagagcta ctgtactttt agatttaaag aataaattat
     2821 atcctaaaag tccagctgtt gcaataattt tttttacaat ttcttttgga gattcttctt
     2881 gtaactttct ttcaattaca tatttagatg atttttcaat tttttcattt ttacatattt
     2941 caaatatatg tgaatttagt gtattttgaa ttaagtttat taaattctga tcactcaaag
     3001 aaacatcctc aaaatatata aggatagttc cagtaattaa acttatttca acacttttaa
     3061 tatatcttac ctacaataaa tgtttttcga tttccaattt taaagaattt ccaacatatt
     3121 taaaagcttt actttttata cgaattcttc ctctaagtct atgaacaatc tcacaagtga
     3181 gtaaattatc atttttcatt ggttaattct cccttctaat tcactcttta acatttcata
     3241 aaatttttta acatttttat ctacttcatc aactgacatt ccttgataaa cttcttcatt
     3301 gtcaactata atcttccaaa ttttatttag ccaatcaact atatcttgct cttttagttt
     3361 tgttttatcg tattctatta aaattttact tgttagataa gaatattcaa tagaatttat
     3421 accatttttt aattttataa tagcagttat atagctttca tgctttttca tttgttcagg
     3481 gaatttatca agtgatggaa taagaagcct tattctacca ggaatactat ggacaacttt
     3541 tactttatta aacattagat aagttttttt caatatattt ttaaacattt cgcctcctta
     3601 atttccattt tttgttaaga gtctatatga ccaccaaatt agagttgccc cacttggtaa
     3661 tagcatttca ttcttaaatt tctttatccc ataaactaaa agtcctgttg ctattaatgt
     3721 tttagtgtca aataagccct tagttttatt atatatagtt atatcagcta gttttccaag
     3781 gctagaaaaa gtattcttaa ttttgccttt tctatctttt aacagctctt tatctaagtt
     3841 taataatttt aaaatgattc ctatcataaa ttgtgtatca atttgtgaat tatcaaattc
     3901 aacagttaaa cttccaagag tttttattat tttaaagttt ttaataactg cgatttttct
     3961 taggttttct tttaaacttt caatttcctc attattattt tttaatttat caatctctac
     4021 tctaattcta ttttttgtag cactttttac ttcaaaaatt ccataaaaat taggtagtaa
     4081 catcttattt tccatatata ctcctttctg taaatatttt tatattcaaa ctatctaata
     4141 ttttatatat aattttgaaa aattttatta ctttgattat aacttattaa ttaaatttat
     4201 gcaagtattt ttttttattt attttttctt taaatttgtt ataaaattat catagtgttc
     4261 agggaaatat tttttaacaa gtttagcata ttcaggatta ttttttattt tcaaaatagt
     4321 atttgaaaat tcttttgcaa gtttagcatc agcttttcta aaagcaatag aagcattagg
     4381 taatttatct tttatagtat caattttttt tattcctttc atagttttta aatattcctt
     4441 accagaaact tctgcaatta taacagcatc aattttttga ttttgtaaat ctaatagagc
     4501 ttctgtaaag ttattatata atttaggaat agatccatta tcttttgcaa attcttcttg
     4561 tatacttcca agttgaacac caacagtttt tctctttaaa tcttcttttt tcttaaatga
     4621 gcttttatca ttaactataa catcatgccc accttcaaaa aatatatatg gtatagagaa
     4681 agatacagct ttttctcttt caggagttgc agacattcct gctataacag catcaatttt
     4741 tttcatttga agagctggta ataaaccatc aaaactcata tcttgccatt taatttcata
     4801 acctaattct tttccaagta attccattaa ttcaatatca aagcctacca ttttattatt
     4861 ttcaagatat tcataaggtt taaattcagc atttgttccc acatataatt ttttagtagc
     4921 aaaagataaa gtagataaga ttaacattaa tatagtaatt atttttttca taattttttc
     4981 tcctttttat tttttaaatg tttgataaaa ttcttcttta atttctttta aaatttcagg
     5041 tttttcaaat atatcaaggc aagataaggc catagctaaa caagcctctt tcattccttt
     5101 atatgtttcc tcttgaatgg ttgcagtggc aaattcaact gtatgtccta ctaaatgttt
     5161 agtagttaat gggaaatttg ggtgaatagt aggacaacat tgacttacat ctcccatatc
     5221 tgttgagcca aaaccttccc tatctttgat atctgtaact cccaaagttt tcaaattttt
     5281 ttcatagagt tccattaatt ttttattagt aacaagattg gcaaaacttg tctcataatt
     5341 tgttatttca agtttagtac cacttgcaag ggctgctccc ttagcacaat ttttaactct
     5401 ttcaactaat tctctcaaat aatcaagtgt ttctgcccta acataaaaat tagcaatagc
     5461 taaatctgga attatattag cagcttctcc acctttggaa ataattccat gtattcttgc
     5521 agaaggtaaa atttgttgcc ttaaagcatt aatagaatta aataaattta aaacaccatc
     5581 aagtgcattt attcctttat gaggtgaagc tgctgcatga gcagtttttc ctttaaaagt
     5641 aaattgaaga gcttccattg catgtgattt tccacttcta aaatgcgttt caccacaagg
     5701 atgaactgac atagctacat caatatcatt aaagatacca agtttagcca tatcaacctt
     5761 agcaccattt gtttcctcag caggtgttcc aataattaaa atctctcctt gtaaatctaa
     5821 tttttgcatt aattctttta ctaaaatacc acttgcaatg cttgtaactc cataggcatt
     5881 atgtccacaa ccatgtccaa tttctggcaa agcatcatat tcagcaagaa tagctatcct
     5941 tgcaccattg acttttttat aacttgcctt ataagctgtc tccaaattag caaagccttt
     6001 ttcaatttca aaaccatatt tctttaaaat atttatatga gcagtacagg ctttatattc
     6061 ttgcatacct agttctggat tattatagag atactcgttt aagtctttta attcattcct
     6121 atatttgtca aaaagttctg ataaaatttc ttttctattg tccatattta cctcctaaaa
     6181 ttttataaaa taaaaaatca gtataacatt gaatgctata ctgattgcta acttatttta
     6241 ttattgaaat attaatatca aaaaatagat atactaaaaa ataaaggtat aaacagccct
     6301 tagcatacaa ttagataagt tattcaattt tatagtaaaa atatttttcc ttatccttgt
     6361 tttgctaaaa aacattatga accctcctaa aatttatttt agctaatata gcatattata
     6421 aaataaaagt caaataaaat tttaaagtat ttttagatat gattttttta attactatta
     6481 aaattgtttt aaattaaaaa taaagttaaa ataactataa aaatatatag aaatttgata
     6541 aaataaaata taaatttaat acgaggaggt aaatttatgg ataataaaaa agatgaaaaa
     6601 attttagaat tagttaatat actaaaaaat acaaaatatt tagttttttt tggaggggct
     6661 ggaacatcaa cagatagtgg tgttaaagat tttagaggaa aaaatggact atataaaaca
     6721 ttatataaag atagatatag gccagaagaa gtattaagtt cagatttttt ttattcacat
     6781 agagatattt ttatggaata tgtggaaaaa gagttaaata tcaatggttt aaaaccaaat
     6841 aaaggacata tagctttggt agaacttgaa aaaatgggta ttttaaaagc tgtcataaca
     6901 caaaatattg atgatttaca ccaagtatct ggaaataaaa atgttttaga attacatggt
     6961 agtttaaaga gatggtattg tttaggttgt ggaagaacag gagatagaaa cttttcctgt
     7021 gaatgtggtg gaatagttag accagatgta acactgtatg gagaaagtct aaatcaagct
     7081 attgttaatg aggctattta tcaattagaa caagcagata ctttaatagt tgcagggaca
     7141 agtttaactg tttatcctgc tgcttactat ctaagatatt ttagaggaaa aaatttagtt
     7201 attataaatg atatggatac tcaatatgat ggagaagcct cattagttat aaaagataat
     7261 ttctcttatg ttatgaataa agttgttgaa gaattaaaaa aattttaaat ttgttaagtg
     7321 taacttaata aggtaaaata aaaattaagt atgtttaaaa taataacaaa agtttaaaaa
     7381 acaaatttca actaaaatat caatataatg aacataaaat tataaaatag taaaataaaa
     7441 tcaaaaaata ttaagccaat aaaaatttat taaaaaataa atgaatttta taataaaaat
     7501 attgcattta atcgtaatca gtgttaatat atacttgata aatttaaaag ataaatttaa
     7561 agctttatct atataaaaac taaggagtga ttataatgag ttttttaggg caagttagaa
     7621 aaaaagcctt acaagcgaac agaagaatag ttttacctga atcaagtgat gaaagagtaa
     7681 taagagcagc ttctcaaatt ttaaaagagg gtttagcaca ggttattctt gtgggaaatc
     7741 aagaagcaat aatgcacagt gcaaaggctt atgaagtttc attaagtggg gcaaaaattg
     7801 tagatcctta taattttgaa agatttaatg attatgtaaa taaattagta gaattaagag
     7861 ctaaaaaagg aatgacccct gaagaagcaa aaaaattatt attaaataat cctacttttt
     7921 ttggagctat gttaataaaa atgggagatg ctgatggaat ggtttcaggc tcttcatcac
     7981 ctactgctaa tgtattgaga gcagctattc aggttatagg tacacaacca ggagtaaaga
     8041 cagtttcatc tgttttcatt atggaattat cacaatttaa agacttattt ggaagtatat
     8101 tggtgtttgg ggattgttca gtaatacctg tacctacatc tgaacaatta gcagatattg
     8161 ccacttcagc agctgaaaca gcagtaaaaa tagcaggaat aaacccaaga gtagcattaa
     8221 tgacattctc aacaaaaggt tcagcaaaac atgaatgtgt tgatagagtg attgaggcag
     8281 gaagaatttt aagagagaga aaagtaaaat ttagatttga tgatgaatta caagcagatg
     8341 ccgccttagt aaaatctgtt ggagaaataa aagctccttt atcagatgta tctggtaatg
     8401 caaatgtatt aattttccct tcattatctg ctggaaatat tggatataaa ttagttcaaa
     8461 gattagcagg agctaatgcc tatggaccaa ttatccaagg attaaatgca ccagtaaatg
     8521 atttatcaag aggttgctca gttgaagata tagttgtatt gacagctatc acatctgctc
     8581 aagcttgtat agattgttaa tcttaactag cataaattaa aataattata taataaaaca
     8641 gatggaggaa aagataaatg aaaatactag taattaattg tggaagctct tcgcttaaat
     8701 atcaattaat aaatccagaa acagaagaag tttttgcaaa aggactttgt gaaagaattg
     8761 gaatagatgg ttctaagatg gagtacgaag ttatagcaaa agattttgaa aaaaaattag
     8821 aaactcctat gccaagtcac aaagaagcat tagagttagt aatatctcat ttaactgata
     8881 aggaaatagg ggttatagct tctgttgatg aagttgatgc aataggacat agagtagttc
     8941 atggtggaga agaatttgca caatcagttt tagttaatga agcagtttta aaagctattg
     9001 aagtaaacaa tgatttagca cctttacata atccagcaaa cttaatggga ataaggactt
     9061 gtatggaact tatgcctggt aagaaaaatg tagctgtatt tgacactgct tttcaccaaa
     9121 ctatgaaacc agaagcattt atatatccat taccttatga agactataaa gaattaaaag
     9181 ttagaaaata tggtttccat ggaacttctc atttatatgt atctggaatt atgagagaaa
     9241 ttatgggaaa tcctgaacat tcaaaaataa ttgtttgtca cttaggaaac ggagcatcaa
     9301 taactgctgt taaagatgga aaatcagttg atacttcaat gggattaaca cctttacaag
     9361 gtttaatgat ggggacaaga tgtggagaca tagatccagc agctgtatta tttgttaaaa
     9421 acaaaagagg acttacagat gctcaaatgg atgaaaggat gaataaaaaa tctggaattc
     9481 ttggattatt tggaaaatct tctgattgta gagatatgga aaatgcagtt aaagaaggag
     9541 atgaaagagc tgtccttgct gaaagtgttt ctatgcatag attaagatca tatataggag
     9601 cttatgctgc tgttatgggt ggagtagatg ctatatgctt tacaggggga attggagaaa
     9661 attcttcaat gacaagagaa aaagcattag aaggtttgga atttttagga gttgaattag
     9721 ataaagaaat aaactcagtc agaaaaaagg gaaatgtaaa attatctaag gaatcttcaa
     9781 aagttttagt atataaaata cctactaatg aagaattagt tatagcaaga gatacattta
     9841 gattagcaaa atagtttata caataaggaa gattatagaa aattaattaa taatattaaa
     9901 acgcttatga tttagatttt aataatcata aagttttaaa taaaatagtg aaataataga
     9961 aattaaacac ataaaaaatt aaaaattagg aggaaactat atggcaaaaa aaatgcaaac
    10021 tatggatgga aaccaagcag cagcttatgc gtcttatgct tttacagaag tggcaggaat
    10081 atatcctata acaccatctt caccaatggc agaatataca gatgaatggg cagcaaaggg
    10141 gatgaaaaac atttttggtg ttcccgtaaa attagtcgaa atgcaatcag aaggaggagc
    10201 tgctggaaca gttcatggtt ctttacaagc tggagcattg acaacaactt atactgcatc
    10261 acaaggatta cttttaaaaa ttcctaatat gtataaaata gctggagaat tattaccagg
    10321 agttatacat gtgtctgcaa gatcattatc tgcacaagca ttatcaatct ttggtgatca
    10381 ccaagatgtt tatgcagcaa gacaaactgg atttgcaatg cttgcaacaa attcagtaca
    10441 agaagtaatg gatttaggtg gtgtagctca cttatcagca ctgaagtcaa gagtaccatt
    10501 tttacatttc tttgatggat ttagaacttc tcatgaaatt caaaaagttg aagtaatgga
    10561 ttatgaagat ttaaagaaat tggtagattg gaaagcatta gaaggattta gaaaaagagc
    10621 attaaatcct gaacatccag taacaagagg tacagcacaa aatgacgata tttacttcca
    10681 agcaagagaa gtacaaaata aattttatga tgctgttcct gatatagttg ctagttatat
    10741 gaaagaaatt tcaaaaatta caggaagaga atataaacca tttaattatt atggagcacc
    10801 agatgcagaa agaataatag ttgcaatggg ttcagtttgt gaagcagcac aagaagttat
    10861 agattactta gtagaaaaag gtgaaaaagt aggtttaata tctgtacatt tatttagacc
    10921 tttttcttct aaatatttct ttgatgtttt accaaaaaca gtaaaaagaa tttcagtttt
    10981 agatagaaca aaagaacctg gttcattagg agaaccttta ttacttgata taaaagcatt
    11041 gttctatagt aaagaaaatg ctccattaat agttggtgga agatatggat tgtcttcaaa
    11101 agatacaact ccagctcaaa taaaagctgt atttgataat cttgcaaaag atacaccaaa
    11161 agatgcattt acagttggta tagtagatga tgtaactcat acttcacttg aagttggacc
    11221 agctatggca cttgcagatc caacaacaaa ggcttgtcta ttctacggat taggagcaga
    11281 tggaacagtt ggagcaaata aaaactctat taaaatcata ggagataaaa cagatttata
    11341 tgcacaaggg tattttgctt atgactctaa aaaatctgga ggagttacta gatctcactt
    11401 aagattcggt aaaaaaccta ttagatcaac ttatttagta tcaagaccaa catttgttgc
    11461 ttgttcagtt ccagcatatt tacaccaata tgatatgaca tctggaatta aagaaggtgg
    11521 aaaattctta ttgaactgtg tatggacaaa agaagaagca ataaaaaata taccaaataa
    11581 tgtaaaaaga gatttagcta aaaataaggc aagattattt attataaatg ccactgctct
    11641 tgcacaagaa attggattag gtcaaagaac aaatacaata atgcaagcag ctttcttcaa
    11701 attggctgaa attatcccat ttgaagaagc tcaacaatat atgaaagact atgctaaaaa
    11761 atcttatgct aaaaaaggtg atgaaatagt tcaacttaac tataatgcga tagatagagg
    11821 agcaaatgat attgttgaaa tagaagttga tccagcatgg gcaaatcttg aagtaacacc
    11881 tttaaatgaa ccaaaggaaa cagctggttg tggtggatgc tgtcaacctg atacagaatt
    11941 cgttaagaaa atagtaagac cagtaaatgc aataaaagga tatgatttac cagtgtcagc
    12001 tttcttagga tatgaagatg gtacttttga aaatggtact tctgcatttg aaaaaagagg
    12061 tgttgcagta gatgttccta tatggaatgt tgataaatgt atacaatgta accaatgttc
    12121 ttatgtatgt ccacatgctg caataagacc attcttaata aatgaagatg aattaaaagc
    12181 tgctccaaat tcttttgcta caaagaaagc agcaggaaaa ggactagatg gattagtata
    12241 tagaattcaa gtatcagctc ttgattgtgt tggttgtgga tcttgtgcta atgtttgtcc
    12301 tgcaaatgct cttgatatga gaccaatagc tgaatcatta gaaacacatg aagatataaa
    12361 tacaaattat ttatataata atgtagaata tagaagtgac ttaatggcac ttgatactgt
    12421 aaaaggttct caattctctc aaccattatt tgaattccat ggagcatgtc ctggttgtgg
    12481 agaaacacct tacattaaat tgataactca attatatgga gatagaatga tggttgcaaa
    12541 tgcaactgga tgttcttcaa tctattctgg ttctgctcct gcaactccat atacaactaa
    12601 taaaaatggt gaaggacctt cttgggcatc ttcattattt gaagataatg ctgaatatgg
    12661 atttggtatg catgtaggag ttgaagcatt aagatctaga attcaacata ctatggaaga
    12721 aaatatggat aaagttgatg aagatatagc tactttattt aaagattgga tagcaaatag
    12781 acaatattct gtaagaacaa gagaagttag agatatactt gttccaaaat tagaagcatt
    12841 aaatacagat tttgcaaaag aaatcttgga tttaaaacaa tatctagtta agaaatctca
    12901 atggataatt ggtggagatg gatgggctta tgatattggt tatggtggac ttgatcatgt
    12961 gcttgcatct aatgaagata taaatgtatt agtaatggat acagaagttt attcaaatac
    13021 tggtggacaa gcatcaaaag ctacacctac tggagcagtt gctaagtttg cagcagcagg
    13081 aaaaccagtt aagaaaaaag atttagctgc aatagcaatg tcttatggac atatctatgt
    13141 agcacaagtt tctatgggag ctaatcaaca acaatttatt aaggctgtta aggaagcaga
    13201 agctcaccaa ggaccatcaa taattattgc atactcacct tgtatcaacc atggtatcaa
    13261 gaaaggtatg tcaaaatctc aaactgaaat gaaacttgct actgaatgtg gatactggcc
    13321 aatatttaga tataatccat cactagaaaa aataggtaag aatcctttac aaatagattc
    13381 taaagaacct aaatgggaaa aatatgaaga atatttaact ggtgaagtaa gataccaaac
    13441 tttagcaaaa tcaaatccag aagaagctaa gattttattt gaaacaaata aaaaagatgc
    13501 tcaaaagaga tggagacaat ataagagaat ggctgcacta gattatagtg aagaaaaaga
    13561 agctgaataa aattaaataa ttgttaagaa tgagagttgt tatgaaatta tttcatagca
    13621 actctttttt actataattt tttcttattt ataattattt aaaagtgatt attgctttat
    13681 aatagttctt tttgttataa tataactagt gaattatttt aaattgaaag gagtttttat
    13741 atgttacaaa caagaaaagt tggaattgtt ggaattggtc atgttggaag tcattgtgcc
    13801 ttatctatgt tattacaagg tgtatgtgat gaaatggttt taatggatat tattccagaa
    13861 aaagcaaaag ctcatgcaat agattgtatg gacactataa gttttcttcc tcatagagct
    13921 attattcgtg atggaggaat tcaagagctt tcaaaaatgg atgtaatcgt aatcagtgtt
    13981 ggaagtttaa caaaaaatga acaaagattg gaagaattaa aaggctcatt agaagctata
    14041 aaaagttttg ttcctgatgt tgtaaaagca ggctttaatg gaatttttgt tacaataact
    14101 aatccagttg atatagtaac ttattttgta agagagcttt caggtttccc taaaaacaga
    14161 gttattggaa caggaacagg tttagatagt gcaaggttaa aaagaatttt aagtgaagtt
    14221 acaaatattg atagccaagt tattcaagca tacatgttag gagaacacgg agatacacaa
    14281 gtagcaaact tttcaagtgc tacaatacaa ggagtaccat ttttagatta tatgaaaacg
    14341 catccagaac aatttaaagg agtagaactt tctgttttag aaaaacaagt agttagaaca
    14401 gcttgggata ttatttctgg aaaaaattgt acagagtttg gaataggttg tacttgctct
    14461 aatttagtga aagcaatttt tcataatgaa agaagagttt taccatgtag tgcttattta
    14521 gatggtgaat atggacattc aggtttctat acaggagttc cagctattat tggaagcaat
    14581 ggagtagaag aaatcttaga gcttccttta gatgaaagag aaataaaagg ctttgaagat
    14641 gcttgtgctg taatgaaaaa atacattgag gttggaaaat cttataaaat agtataaaaa
    14701 tatctatggg ggttaaagtg cagagcaaag aaagtaatat aaaactgtta ttattaggta
    14761 gagcagtatc cttatttgga aatacaattt atctaatagt tttaccattg tatatattaa
    14821 atattactca aaatttaaaa acaacaggta ttttctttgc ttctattaac cttcctacaa
    14881 taattatttc accacttata ggaacattaa tagagaaatt taataaaaag aatataattt
    14941 tgatatgtga tgttctaact tcaatgttat attttatttt attcatatat tttaaaaatt
    15001 ctaattcgtt aattttttta cttatagttt cattaatttt aaatatcatt tcaaaatttt
    15061 ttgagatagc ctctaaggta ttgttttcag aaattaatac ccctgaaaca cttgaaaaat
    15121 ataatggttt acaaagtttt ttagaaaatg cagttatgat ttttggacca gttattggaa
    15181 cttatctatt tgctacattt acttttaatt ttgttttgat aattatatcc ttagcttatt
    15241 ttttatcatt tttacaagag ctatttataa aatatgaaaa aaatactaat ttatcaaaag
    15301 aaaaatcgag tttctttaaa gattttaaag aaggaataaa ctatataaaa agtaaaaaaa
    15361 ttatttttaa tttttttata ttagctatgt ttttaaattt ttttatagca aataatgatg
    15421 agataatcaa tcctggaatt ttaataaaaa aatatcaaat atctgaaaaa ttatttggat
    15481 tttcagttgc ttgctatgga ctaggaagtg tagttgcagg aatttttatt tattataata
    15541 acaaatttaa atttcttaaa aaactaaaac cattatttat attaaatagt tctctaatgt
    15601 gtttaggagg gctcttatct ataatactat ttaagtataa tcattatata tattttacaa
    15661 tttttatatt ttttcaattt ctaattggaa tgataaccac ctttgtaaat gttccattaa
    15721 tatcctcatt tcaaaagaat gttgagattg aatatcaaag tcgttttttc tcaattttat
    15781 cattcttttc taatggatta ggtcccttag gagttttata tgcaggatat ttatcatcat
    15841 atatcggtgc tgatgttaca tatataattg ataatgtagc tattataatt atagtgtttt
    15901 tagtttttaa taatataaaa gaagctgttg taaattaaag taaaaaaaag attactgtga
    15961 agtcctataa tgttgaaaga gcattttgga gctcttgaaa cattataggc tgtcaagtaa
    16021 tcttcatatt tattaacttt tattttttct tagcatattt aatagagtca aatgcaacag
    16081 cagtaacaat tattatacct tttataatat attgccagta tggactaaca cctgtataag
    16141 taagtccata gtttataatt gttaaaatta taactcctgt aataactcct gaaattctac
    16201 caacaccacc atagaacgaa actcctccaa ttacacaggc agcaatggca tccatttcat
    16261 acataaatcc taggttattg gttgcagaac caatacgtcc agcttctaag aaaccaccaa
    16321 aagcataata tgccccagat aatgcatata ttcccataag agttagaaca acatttactc
    16381 ctgatacctt tgcagcttcg ggatttccac caactgcaaa tacattctta ccaaattttg
    16441 ttttattcca taaagtccac ataattaatg ttgcaatagc agcataaata attaaatatg
    16501 gtattgtata cgagcctatt tgtatatagc cttgtgcaaa tttactatat ttttctacaa
    16561 atccagaaat tggagcagct cctgctttat cataataaag agagtttatt ccatacacaa
    16621 tagtcattgt tcccatagta gctataaatg ggtgaacatt taatgttgca acaactatac
    16681 catttatact tgctataact acaccaacca ctacaacaat taatatagtc gtaaatattg
    16741 aaaattctcc taattttgga aatgctttat ttacatttgt cattgattgt aaaagtgttc
    16801 cagatataac agcagaaagt ccaacttgtc tacctgctga taaatcagta ccttgtgtta
    16861 ctataagccc agcaacacca agtgcaataa ttgttcttac agatgattgt gtaagaatat
    16921 ttttaaagtt tcttatactt aaaaaagtag gttcttttat tattattgca acaagcatac
    16981 aaaacaatac aagatatagt ccactttcta taataatttt tttataatct atttttcctt
    17041 cattagttct tgcaatcatt tcttattctc cttcttaatt tttatagata tttagctgat
    17101 aattccatta tttcttcttg attagtttca gatgttttaa caattcctgc aaccctacca
    17161 ttactcataa caagtattct atctgttact cctaaaagtt caggcatttc agaagaaatc
    17221 attataattc ctttatcttt tttagcaaga tctatcatta attgataaat ttcatatttt
    17281 gctaaaacat caatacccct agtaggctca tcaagcataa gaacttctgg ttcagttagt
    17341 agccatcttc caataattac tttttgttga tttccaccag aaaggcttcc aatttttgta
    17401 gagtatgaag gagtctttac cctcatacta tccactatcc atttggtatc tttttctata
    17461 tctttatttt taagaagttt aaatttattt ttatatctat ctaagttaga gataacagag
    17521 ttaaatgcta catctaacat tgaaaatatt cctgtacttc tacgttcttc tgttactaat
    17581 gcaaaaccat tttttatagc atcttctgga cttttatttt ttacagattt accatgtaaa
    17641 agaatttcac catgttcctt tggtctcatt ccaaatatag tttcaactat ttcagttctt
    17701 ttagatccaa caagccctgc tattcctaaa atttcccctt tataaagttc aaaacttaca
    17761 tcttgtatag atggttgatt taaagcagtt aaatttttaa cttgtagtat catttcctta
    17821 gctttattat cttttttagg gaaacgctca gttaaatctc tacctaccat catactaata
    17881 atttggtcag ttgaaatttt tgatacatca ttagttgata tccatttacc atctcttaaa
    17941 atagttattt catcagaaat catttttatt tcttccattt tatgagaaat atagataatt
    18001 ccaactccac tttcttttaa ttttttaata attctaaata gatgttcaac ttccttttca
    18061 gttagtgaag aagtaggttc gtccataact attacttttg atttatatga tactgccttt
    18121 gctatttcta tcatttgtct ttcagcaata ggtaagtctg ctactttctt tttagggtct
    18181 actttaatat ctaaatcttt aaaaatatta atagtatcat tgtacatttt cttttcatct
    18241 acaaaaaaac ctttcatagg atatctccca agccaaatat tatcaagtac atttctttgt
    18301 aaaacttggt ttaattcttg gtgaaccata gaaactccat tttctagggc ttcttttgta
    18361 gatttaaaat taacttccac tccatctaat aaaatttttc cactattttt ttcataaatt
    18421 ccaaataaac atttcatcaa tgttgatttt ccagctccat tttctcccat tagagcatga
    18481 acagttccag gtttcagttt taattgaaca tcatctagtg cttttacgcc aggaaattct
    18541 ttggaaatat tttccatttc taatacatat tttagatttt ccataaatac cctattcctt
    18601 ttcctttatt ttccattttt aaaaaaagga gattgatgta caatctcctt taagattact
    18661 atacaattaa ttcttatttg aagtctgcaa cattagattt atctattcca atactaggaa
    18721 ttaatattac tttattatct aattttaaat cagttccttc agtaggttct tttccttctg
    18781 ctaaattaac taccatatta aatgttgcac ttgcttgtcc ttttgcatca ttaaggacag
    18841 ttcctgccat ttctccagct tctattttaa ctaatgcttc tggtaatgca tcaacaccaa
    18901 atgttggtaa aacttttcca gcagctttca ttgattcaat agctcctaat gccattccat
    18961 cattattaca aataacaact tctatttttg aaccattagg tcctgataac caagcatcca
    19021 ttttatcttt tgcagtggct gtatcccaca tagcagtatc tttatgtaat tcttctgttt
    19081 ttattccatg atcatttaaa gtagaaatag aatatttagt tcttgcaact gcatctggat
    19141 gtccaggttc tcctgttaac attacatatt ggataattcc atctttattt aagtcaagat
    19201 caggattttc tttccataat ttttcaatta attcaccttg tgcaattcct tgtgcattag
    19261 ggtcaattcc aacatagtat aatttatcat aagaagctat tgcttcatca gaaggttttc
    19321 tgttatagaa tacaactgga atattttttt cttttaataa attaataatt ccatcagcag
    19381 cagaagcatc aaccaagtta attgcaaatg cttttactcc tttttctaaa actgcttcta
    19441 tttgttcttt ttcagtagca acactatttt gagagtcaat agcagttact tcaactgtat
    19501 cagctttagc cattgcttca gcttcaaatg cttttctaaa taaagctata aaattatcat
    19561 caaatttata agcagttaga cctattgata atttttcacc tgtaggagca tcagttttag
    19621 cttcttcctt tttttctcca caagcaacta atgctgaggc aagaataatt gaacccaata
    19681 acataccaaa ttttttcata taaataccct cctaaatttt aataaaataa taatttttta
    19741 tttgtattat atattttcat atataataca atatataatt ttttattgtt ctttgtcaat
    19801 agatttttat taaaaataaa taatttttcc atattttaga aaaaatgtat ttttataaga
    19861 caaataattt taactatttt acttaatcaa tatttaaata aaaagtgcca cagctccttt
    19921 tataccagct tcattaccta aaacaccaac ttttatttct aaattttcaa gtgcaggggg
    19981 catagtgtat ttttttaatt tctcttttat tggaagtaaa atttcatctc ctgcaagaga
    20041 aatgcctcca cttataacta tacactcagg atttattata tttaaaagat ttcctattcc
    20101 caaagctaaa tagtcacttt catactctat taaatctttt gaaaattcat ctccttttct
    20161 agcagcatca aaaatatttt ttgcttcaag ttcagctaaa ttcccattga tttctttaaa
    20221 aagtaagttt tcttcattta attttaatct ttcttgtgct tctttaacaa gagagctagc
    20281 tgaggcatag gcttcaaaac aaccattttg accacaacca caagtttttc catctttaac
    20341 taccttcata tgtcctattt ctccaccaac tcctgacata ccagaaataa gatttccatt
    20401 gtaaaaaatg cctccaccta ttcctgttcc tattgcaata gttattgaag atttttttcc
    20461 ttttgcagct ccaaagatag cttcaccttg tgcaattata ttagcatcgt tttcaattct
    20521 tgtttctatt ccacttaatt tttccatttt ttcttttaaa tttagatttc tttcccaatc
    20581 aaaatttgca aagaaaccta ctgtactttg attttttaca ggaccaggta ttcctattcc
    20641 tattcccaca acggaaaaaa gtggaatttc tttttctaat attaattttt ttgcagtttc
    20701 ccaaattctt tctaatgttt tatcaacatt ttgatgagag tgagttttaa taattttgct
    20761 atttattaaa tttccttctg aatcaaccac tcctattttt gtattagttc cacctaaatc
    20821 aataccaata taatgtttca tactagctcc tataattaat attttatttt ttcttagatt
    20881 ttaatatttc tttcaaaata aatgttgttg ctataacccc atcattagtg gcagtagcaa
    20941 cctgtcttac ttctttttct ctaatatctc caatagcata cattttatca gttcttgttt
    21001 tcatagtttc atctgttatt atatatcctg cttcacttaa atttacgaat tctccatata
    21061 attcaatatt attttttgtt cctaaatata agaaaacaaa atttgttgat actgtttctt
    21121 tattaccatc tatttctaaa tctaattctg ttacaaattc ttctcctttt atttctaaaa
    21181 gtttcacttt tttagtaatt tttacatttt cctttgataa aacagcttct tttaattctt
    21241 cattacaatc taaatcatca gaagttaaaa agatatttac ttcctttgca tatctagtta
    21301 aaaataaagc ttcttcaata atttcgtcac cttttccaac taatgaaaca actctacctt
    21361 ttgtaaaagc tccatcacaa gttgcacaat atgaaacacc tgcacctaaa aatttacttt
    21421 ctccctttac tttctttgct ccaatttttc ctagtccagt tgctattata atatattttg
    21481 ttttaaagtt tcctgcatct gtttttacaa tttttatttc atcataagga tcaaaaccta
    21541 aaactgttgc aggttttatt tcacaaccaa aatctaaagc ttgttttttc attgtatcat
    21601 aaatttcttt cccagaagct ccaatatgaa agccaggata attatcaatc tgatgagaca
    21661 ttatcatact tcctattcct tctttttcca aaataagagt agataaattt cctctccctg
    21721 catatattcc agctgttaat ccagcaggac cagctccaac aattacaaca tcatatattt
    21781 tttccattat tttcatctcc ttaaattttt tatagtattc caactctttc taaaaatctt
    21841 ctttcttcac caatagttgt attatctgta tgtccattgt aaacaacagt ttcatcaggt
    21901 aattttgata atttttctaa actatgacat aacatttcta aactaccagt aggtaaatca
    21961 tatctaccat aacttcttct aaatagtgta tctcctgaca ttaaaatttt atctttttca
    22021 tcatagaaac tttttgaacc aatagtatgc cctggagtat ctataacttt aaaatctcct
    22081 attgtatctc cttcttttac tgtaataagt tcacctttaa atctaaaaac ttctccaaaa
    22141 attgcatctg ataaactaag ttctgaatta tataaaaaat ctttatcttc ttctcctata
    22201 tacacttttg cttctggata atgtgaagct aaatcattca atccttctat atgatctcca
    22261 tgtccatgag ttaatattat atattttaaa tttaatttat gttcttctat atattcataa
    22321 acttgtttta aatttctacc tccacaatca aaaaaataag ctatattatt ttcatcataa
    22381 gctaagaaac aatttgttcc ataagctcct aaatgaaagc attttactct caatgttctt
    22441 ctcctttcaa atatttatat tgaacctaat acattataac aaattgaact aaaatagtct
    22501 acctttaaga tttatatttt tagtataaaa atttcaagaa tataaaaaag agaactcttt
    22561 tagaaatttc tattctaaaa aaattctcta ctatttgaca aacaactatt taaaaaaatt
    22621 ctcttattat ttacttattt tggtattcta taaatctcta tttcttttcc taaaaacttt
    22681 tcagcagttg gtttaaaatg atatgtttct cctgtaacaa aaaatataat tctgcctttt
    22741 tcttttttat catttaaaag attaagtgaa cttaaagttt gagtagccct ttcaactatt
    22801 tctactgctg gatctaccac tttgattttt atattttttt ctatatcttt tcttataagt
    22861 ggataatgtg tgcaacctaa tactaaggta tcagtatttt taggaatttc tgataaatac
    22921 ttatttagaa gttcctttct attgtcaaaa gtatcccaac cactttctat catttgtgca
    22981 aactcaatac aagcaatttc tttaacattc aactcactat caagcatttt agctttattt
    23041 ttataaccat gagagtctgc tgtaaattta gttgagatta cagcaatatt cttatttttt
    23101 gtatttttac ttgctatttt tactcctgct tcaacaattc caattatagg taaggaaaat
    23161 ttttctctta aataatcaat agcagcagtt gaagcagtat tacaagctac tattactaat
    23221 ttacaattat ttttcacaaa aaaatctaaa attctttcag ttaatttttg aagttcattt
    23281 ttagtttttc cagagccata agggaaattt ccattatctc cataatatat atagtcttca
    23341 ttgggaagag attttatcat ttcttttagt acagttgttc cacctaaacc agaatcaaat
    23401 atacctattt tttgagtttt ttccgccata ttttttcctt ctttttataa gattataata
    23461 aatacttttt tataatatca tatttttttt ataatatcaa tttatctata aagaaaaata
    23521 taaaaaagct gttgcaatta tgtaacagcc tttcaacttt tatattattt taccaagtga
    23581 gtaatttttt catctttaaa atctaaatta tgtatagaat ttatatatct aattgttttt
    23641 gataaacctc ttacaacaag agtttgagtc ctagcaatat ttcctttcct ttttacacct
    23701 tctaataaat ctccacctgt gataccagta gcagaaaaaa ttatttcatc atcttttgct
    23761 aaatcatcaa gttttaagat ttctccaact tttaatcctt gttcctcaca tcttaatttt
    23821 tcaaatttag atattttatc attttctaga gttgcacctt taacttcact tctaagtttt
    23881 aatcttgctt gcatatctcc acctaaggct cttataacag cagcagaaat aactccctca
    23941 ggagctcctc caacaccata aagcatatcc acatctgaat ctatcataca agtaagtatt
    24001 gaaccagcaa catctccatc tggtagagca taaactttta ttcccatagc ttgtaaatct
    24061 tttattaatt ctttatgtct tggtttatct aaaacaacta tcattaaatc ttttaactct
    24121 ttatttaatg cttttgcaac agcatgaata ttatcttcaa gaggttttga taaatctatc
    24181 ttcccttttg cttctggacc aacaattagt ttttccatat acatatcagg agcttttaaa
    24241 aaacttcctt ttttaccaac tgctaacaca gtaatggcat ttggttgtcc ttgagcagtc
    24301 attctagtcc cttccacagg gtcaacagca atatcaacag ggtcaacata agtaactgaa
    24361 tctttttctt cttcattata gatttgacca actttttctc ctatatataa cataggagct
    24421 tcgtcaattt ctccttctcc tattactatt tctccatcaa ttgcaagtct attaagcata
    24481 gttctcatag catctacacc agcttggtca gctgattctt tctttcctct accaacccat
    24541 ttatatgcag caagtgctgc tgcttctgtg actcttgcaa attccaaagc tagttctctt
    24601 ttcatttttc ctcctcagta ttttcagttt tattattatt tttttcaaca tatttatata
    24661 ttacttcatt ttcttttacc atttggaaca tatttct
//
