LOCUS       NC_018664.1            24538 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_018664.1 Gottschalkia acidurici 9a, complete sequence.
ACCESSION   NC_018664
VERSION     NC_018664.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:48:03
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 68659
            Orig. end    :: 93197
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24538
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[78659:83197]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14538
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..24538
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24538
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             652..1236
                     /locus_tag="ctg1_64"
                     /transl_table=11
                     /translation="MIKSCANKVTSFLVSNDAINDEEYEVYSYGFETLLAFIINISVIL
                     LLGLIVGKFVQTLLFLTCYCPIRQFTGGYHANSYRNCLLVFVFIFSINIITLDKLSYMN
                     LNEVIICTTLISYIGICLLAPIEHRYNPLSTRQRKSYKKVAILLTSIVLIFVLLGIKYK
                     PIYEYVLYSASVLVWIFIMLILAIIKKIRRE"
     CDS             1241..1387
                     /locus_tag="ctg1_65"
                     /transl_table=11
                     /translation="MKKYLTSILKYVGSISAFAVSLSANTTSTWISHQPKVPEGVRKFK
                     KIN"
     CDS             complement(2416..3654)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_66"
                     /sec_met_domain="AA_kinase (E-value: 5e-54, bitscore:
                     180.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIIVQKYGGTSVGNVERIFNVAKRIIKTKESGSDVIVVVSAMG
                     DTTDELIEKAKQVTLNPSSRELDMLVSTGEQISISLLSMAINSLGHKAISLTGPQCGVL
                     TTGKHKNARIKEINTQRLKSELSKGNIIIVAGFQGINEKNDITTLGRGGSDTSAVAIAS
                     SIGAKKCEIYTDVDGVYTTDPRLVSTANKIDKISYDEMLELASLGAGVLHPRAVELARK
                     YNMPLIVRSSLNDNPGTEIAEVNSMEKAIVSGVALDKDIAKVSVIEVPDKPGIAFKVFS
                     ALASNGIFFDMIIQNVTRNSVNDITFTVKGDELNEALDVTRKVAEEIGAKEVLYDRSVV
                     KVSIVGTGIAGSADIASSFFQTLYDLGINIGMISTSEIKISCIIEEGKGVEALNALHSK
                     FGLDKVSGKNKAV"
     CDS             complement(3758..4999)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Homoserine_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_67"
                     /sec_met_domain="Homoserine_dh (E-value: 2.7e-57, bitscore:
                     190.9, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVGLLGLGTVGSGVYEILRDKKESLKKATGKNIEISKILVRDK
                     SKDRGLGVDPSILTENVDDILNDSSIDILVEVLGGIELPYEYIIKSLRSGKHVVTANKA
                     VISPYLDELHKLADENNVGLLYEASVAGGIPVIKGLKDIIKINSVSNIKGILNGTTNFI
                     LSKMYDEDLSFDEALSLAHKYGYAEADPTDDIEGFDAARKISILASLGFGAHVGFDDVV
                     CRGITSVSASDIKNFKDLSLVPKLIGSATIAGNECSASVEPLLVDDSAPFASVKDAFNI
                     VSIEGDIVDELQFYGRGAGKNPTANAVVTDILDIVLENYKEYSFTNNTDIKPSGSKLFK
                     GNYYMRVSNVNSDKLLNSINDIGLNHKVISSGHELVILTEKIDSESMESMIAKLNLPKG
                     SFCYLRIESENVNI"
     CDS             5261..6739
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_68"
                     /sec_met_domain="PALP (E-value: 5.3e-15, bitscore: 53.0,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLYYKSTRGDSEKVNSLEAIVKGIANDGGLYVPSYIEKIDMSLN
                     ELSKMNYQELAYYIINKFFPDFSEEELKDCVNSAYDEKFDTKEIAPIVEKSGAYFLELF
                     HGPTLAFKDMALSILPYLLKTSATKLDYLKEIVILTATSGDTGKAALEGFKDVDGIKII
                     VYYPENGVSEVQERQMITQEGKNTYVVGIKGNFDDAQSGVKEAFNNREFNLDLDSEGYV
                     LSSANSINIGRLVPQVVYYFHGYIELLRSGKIKEGDKINVVVPTGNFGNILAAFYAKKM
                     GLPINRFICASNENNVLSDFFKDGVYDRRRELKLTNSPSMDILISSNLERLLYELSGED
                     DENLKELMDKLSQDGIYEVSDRIKVGLKDFYGNFATEEETHSAISKVYKGTDYVMDTHT
                     AVAYSVYEKYKDETGDNTPTIIDSTASPFKFTRSVSDSLGIEIEGKNDFELIKELSNKT
                     GLIIPNSIKDLETREILHKTVCNKDEIKEAIKKY"
     CDS             6758..7642
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_69"
                     /sec_met_domain="GHMP_kinases_C (E-value: 4.6e-06,
                     bitscore: 24.4, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.7e-13,
                     bitscore: 48.1, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEVIVPATSANIGPGFDTLGIALNIYNKFTVEEIEAGLIIEGCE
                     EKYADESNLVYQSMVKCFEKVGYEPKGIKISIETDIPVSRGLGSSATCIVGGIIAANEL
                     AGSPLNKKKILELATEMEGHPDNVAPALFGGMITSVYDEKVYYSKVNIAKGLKFLALIP
                     NFKLSTKKSRSVLPKVVPHSDAIFNVGRVALMISALQNGEFDLLKIGGQDKLHQQYRGA
                     LIDGYDIILEHCKNIGVKGVFLSGAGPTILVAVEEDDNETYKEINKILDTLENKWEIKE
                     LSIDYKGAFFKKV"
     CDS             7668..8114
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MYSIESKYLVIDKDILPDVFEKVLLAKELLRTGEVKEITEAVKKV
                     GISRSTFYKYKDSVFTLDERSMGKKVTLSFLLSHMQGVLSNVLQTISANGGNVLTINQD
                     IPIHDVANVSITFDVSHIKISIEEVIEEVKSIEGVQKLVVVTME"
     CDS             8141..9115
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MKQKRLVALGVFILLLILNTAFSSVENSIYTSKGEWYEEIHTQGS
                     IEQLALLEVDGIIQDTGSGYAGLGTNYNHQTFLKQLEYAFENESIKGVVLKVNSPGGGV
                     LESDEIHRKISLLKKEHKKPVVVYMDGVAASGGYYISAPADKIVANRNTMTGSLGVIME
                     GTNYHQLAENYGVKTDVIKSGAYKDIFSPMKEMTPEERAILQSLVDESYQFFVDVISEG
                     RKLSKERVLEIADGRIYSALQAKELGLIDEIGYLEDAISSAAKLSNADNPTVVKFKQPK
                     WSAFDTVFSYVSKYYNKSLGTNMIEIDKFTKSDRPKLMYLWIQ"
     CDS             9128..9568
                     /locus_tag="ctg1_72"
                     /transl_table=11
                     /translation="MRTYRLAGFWTRFLAYMIDILTIVSISGIILRGYAKEIPFLGISM
                     VSIGIIGFIYFTVMTKLLGQTLGKMIMGIKVVRIDNKELDWITLVYREGIGRFISQLLG
                     LHLGYIWCGFSPRKQTWHDSISDTYVVFIDELTCKHMIEVQE"
     CDS             10001..11113
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_73"
                     /sec_met_domain="GCV_T (E-value: 7.8e-92, bitscore: 304.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 3.2e-22, bitscore: 75.7,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKRTALYEMHKKHGGKLVDYAGWELSSDFAGLGLVAEHQAVRNA
                     VGVFDVSHMGEIEIKGPEASKFAQYLMTNDLDSIGDGQVIYTYFCYEDGGIVEDLLVYK
                     RNDQDLLLVVNGANIDKDVEWINQHASKFDVTVIDSSPQISEVAVQGPKAQATLQKLVN
                     FDLDEIKFFHFKEDVDVAGVKCIVSRTGYTGEDGFEVYFANDDSIKVWEAVFEAGEEFG
                     IQPAGLGCRDTLRFEANLPLYGNELTKDNSPLEAGYGFFVKVNKESDFIGKAALQKQKE
                     EGLKRKVVGFELVDKGIPRHGYPVEVNGKEVGYVTTGYAAPSVGKTIGMAMVDIEYTEL
                     GTELEIVIRKKKAKAKVISRKFLERHNKSK"
     CDS             11225..11605
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_74"
                     /sec_met_domain="GCV_H (E-value: 2.6e-44, bitscore: 147.5,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIVEGLLYSEDHEWIKVEGNVVTIGVTDHAQDQLGEIVYVELP
                     EVDDEFNAGDAFGVIESVKAASDSFLPVSGKIVEVNEALDDEPGLVNEDAYANWIVKVE
                     LSDASELDSLMDAAKYEAFCAE"
     CDS             11727..13073
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_75"
                     /sec_met_domain="GDC-P (E-value: 2.6e-140, bitscore: 465.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRYIPNTDAEKKEMLDSIGVSSIEDLFSDIPSDLRFQGDLNIGK
                     GLSELEVVKHMQDLVSKNKTTEELTCFLGAGTYDHYIPSIVKHLAFRSEFYTAYTPYQP
                     EISQGTLQIIFEYQSMICNLTGMDVTNASMYDGPTACVEAAILACSDAKKDKIIVSKSV
                     NPETREVLKPYLHARNLEIVEVDTENGATNLEQLKSLVDEDTAGVIVQSPNFFGIIEDV
                     EEVEKITRQAKKAKLIMYTDPISLAVLKSPKDMNVDIVVGDAQVLGSPMAFGGPHIGFL
                     AVNSKLVRKIPGRIVGQTEDVDGNRAFVLTLQAREQHIRRYKATSNICSNQGLNAIMTT
                     IYLTTMGKEGLREVALQSTQKAHYAFNELTKSGKYKPLFPGQSFFKEFAVTSDKCAKEV
                     NEGLLKENILGGYELSKDYSELANGLLLAVTEKRTKEEIDKLVSAMEVL"
     CDS             13075..14538
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: Aminotran_5"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_76"
                     /sec_met_domain="Aminotran_5 (E-value: 1.6e-06, bitscore:
                     24.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 3.7e-10, bitscore: 36.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKYDKLIFEVSKEGSKGYSLPQLDVAEVELSDIIPSKYLNEGK
                     IDLPEVGEFEVVRHFTNLSNKNHGLDAGFYPLGSCTMKYNPKINEDMAGLSGFTNIHPY
                     QSEDTVQGALEVMYNLDEKLSEIAGFARTTLQPAAGSHGEYTGLLVIKAYHEKNGDTQR
                     TKIIVPDSAHGTNPSSAQVAGFDIIEIKSNKDGSVNVESLKAALENKEEIAGLMLTNPS
                     TLGLFERNIKEITSLVHEAGGLNYYDGANMNAIMGKVRPGDMGFDVMHYNLHKTMSTPH
                     GCGGPGAGPIGVREDLVEFLPTPVIEKKDDKFVLDYDRPNSIGSIKGYYGNFSVLVRAY
                     TYILTMGAEGLREASESAVLNANYMMNKLKEDYYLPIDQVCKHEFVLGGLQDKSTGVTT
                     MDVAKRLLDFGYHPPTVYFPLIINEAMMIEPTETESKATMDGFIETLITIAKEAKEDPD
                     KLHNAPFTTQVRRVDEAKAAKDLILKYTK"
     CDS             14598..15272
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MELNVLSLGKYNYEKSLELQFDLLKKRQEDKIKDTLILVEHPHVI
                     TLGKNAHKENILVSGEHLKKNGIDLVEINRGGDVTYHGPGQIVGYPIINIKEKKMGIKD
                     FVSKLEEVFIALLNEKYGIIAIRDNINNGVWVDKNKIVALGLAVKRWVTMHGFAFNVGT
                     DLNFFNLIVPCGVQGRGVTTVEKLTGKEVDLEQEKSDLLRYFIEIFNYTSIKEVTIDDL
                     EV"
     CDS             15275..16138
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_78"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-16, bitscore:
                     57.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELKRKPEWLRIEKRKGQNLGYVKGLLNKLSLNTVCEAANCPNR
                     AECFSKKTATFMILGSECSRNCKFCNVTHGKLQEPDPNEPENIAKATEELGLKHVVITC
                     VTRDDLKDGGAGHFAKTIEEIRKRNNDIIIEVLISDLKGRIEDLKVIVDANPDIINHNV
                     ETVPSLYDKVRPMAIYKRSLDVIGNIKKLNPKIFTKSGIMLGLGETEEEVIELFKDLRE
                     VDCDFLTVGQYLPPSSKHVELKEYITPEQFDKYKEEALKLGFKFVASSPLVRSSYKAAD
                     MLEAAK"
     CDS             16237..17541
                     /locus_tag="ctg1_79"
                     /transl_table=11
                     /translation="MIKRIFSVVILSILTTIVSGCSINGSPEDLMRPPKLESNREQVKV
                     ALQEYLPQNAKLVIPPSNDKPSAIKFLDLDGDGKREAIIFYNLDLDENPLRALILKNEN
                     KKWNNKGELKILGQDLDKVFFKDIDGDGGLDIIIGSKVRYSLSKNLNIYSFKNGNIDEL
                     LESTYEHLVVEDLNNDGLAETILLKSNKEQKQVRGELYKYNQGKVEMMDEVNFENISEI
                     NSIKEGYIGENTQGVVISTTGIDKLLKIYILKAEDNSLVNVVEGGFIESEKVPNIEYVL
                     PQDIDKDGIMEFAIPKVQKRNDEQIENPTSWLTEWYSWDGDKSIVLKKINYYDEISNFS
                     FDFPLTWRENIIVTNSKKDTNIISDEEWIKVDYRDNSEKPKRYHLFTIYIYTDEGLKRK
                     DHSKNKEEPVKILEDIDKNYFIVLGDDIKKEKIKN"
     CDS             17608..18309
                     /locus_tag="ctg1_80"
                     /transl_table=11
                     /translation="MSRILVLEDEDDIRAFIVINLKRAGYEVLQAATGEEALDIISTEK
                     NIDISVLDVMLPGIDGFEVCRQIRDKDKTMGIVMLTAKAQELDKISGLSMGADDYILKP
                     FSPAELTARIDALVRRVDLLKGKSNDMKNASSGPFTIDTSARVILKNNREIDLTQIEYM
                     IMKLFIENEDQSLTREEILKSVWGKDYYGDPKIVDVNIRRLRRKIEDNPSDPKYIRTVW
                     GYGYRWRKEED"
     CDS             18278..19714
                     /locus_tag="ctg1_81"
                     /transl_table=11
                     /translation="MDIDGERKKISLQGIKRRWVYNYILIISSVLLLLEGAFIIFIKNY
                     YYDSISQNLSNKVNTATDFYNKYLNNKLDTVGNIAEQLVKDFAHKEQLELQIIDTEGNI
                     VMSSSGFVMYEKVTTGDYKSAIKGQSSNWTGINKETGEKIMSVSSPLKQGKNKVVGVVR
                     YITSLEETDNVIKILIASSLIFIFIMLFLMLVLSMIFSKSIINPLNELNEVAKKMAQGQ
                     FSERVEKRYNDEIGELSDTLNYMAGEIVKTTQLKNEFISSISHELRTPLTSIKGWGETI
                     LTGGLEDKYEAEVGLKIIIKETTRLAQMVEELLDFSRIESGRIFLHLQQIDIVSELSDI
                     VHITKLRGIKDGVTLEYTHQEEIPEIMADQNRLKQVFINILDNAIKFTDSGKKVYVDIY
                     SDEENVIIKIKDEGAGINEEDLPKVKEKFYKGQSKKSGSGIGLAVCDEIIKLHNGTLDI
                     ESTLNVGTVVTITLPLITES"
     CDS             19736..20560
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="MHNKIQIGEMAKLHNISAQTLRYYDKIGLLKPEYMDKDNNYRYYN
                     IEQFAHLDSILFLKELGMSLEQIKEYFKKRDIESVLELLKQRDSDIEKQIKLLKRRQRN
                     LQDKVSMIELYMQKKEYNNYQLKDIPSRNMVHLKSKLSKSKTDFEYGLKTLSKLIGDEI
                     YFFNSMITCVIDKKSIEKGIYDYWSSIGLLFSEHLLENENIETIPAGKYASIVYGGNYD
                     KGKEYYEKLLNWIKEHNLQVVGDSLLITITDSVFSDFEEEYINEIQIPVKKY"
     CDS             20625..21986
                     /locus_tag="ctg1_83"
                     /transl_table=11
                     /translation="MSNKVDLLNDDVRKTFFRYLIPSIGGMLGTSLYVLADTMFVGRGI
                     GSQGLAALNISIPMMNVFNGLGLLFGIGGATALSISRGQNDEDQVNHIFTKAMLMAGLL
                     GIIFTIVRIFFLDELCTFLGASGTTLQMAKDYLGAVMSFSIAFLLNSALTVFVRNDGAP
                     KLAMWGMLSGSIANVILDYVFIFIFGWGMWGAAVATGMSPVISLVILSTHFIRKNNTIK
                     IIKTKLQLNILKRIVANGGSSFIVEISSGIVIFAFNNVILDITGDIGVSAYSIIANLSL
                     VCTAIFTGIGQAIQPIVSINYGARKIERVYESARMAIYWALGLGVVFYMIGILFPNALI
                     SIFNKDNAELADITSRGIRLYFIAFIFMGLNIVMASYIQSTEQARTSMIISLSRGFIFI
                     ILFLAILPKVFGIDGVWLTLPLAEIMTVILSVVCFKSCRDAISYSIKKKRLMVK"
     CDS             22236..22817
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MKINTRDMILISMFAALTAIGAQLRIPTEPIPFTLQVLFCMYSGI
                     LLGSKKGAFSQILYVLLGLAGLPIFAEGNGGPSIIISPTFGYLLGFIACAYVSGKITEN
                     FKDVNIFKIALATVSGLLVVYIVAVPYLYLILTKVMNSPTTLNGVVKTGFLAFLGQDLV
                     KCAIVSATSVLIIPALRKSGYLEVKKEAVH"
     CDS             22819..23796
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_85"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-16, bitscore:
                     57.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFINQIKNKVLEGSNIDYKEALKLISIDNGDIDNLKLLLDGAD
                     QIREKYNGDKVDMCSIMNAKSGKCSEDCKFCAQSGHYTTGINEYSLINYDEAYQRVSEM
                     EQKGVDRFSLVTSGKGVTDEEFSNLLDIYGKLNENTNISLCASHGVISYEQAKKLKDTG
                     INMYHHNIETSKNYYNEICTTHSYEERVGTIRNIKSAGMEVCCGVIIGMGESIEDRLNM
                     MFEIRDLEVDSIPVNVLNPIKGTPLENLEILEPMEILKTIAVYRYIVPKSHIRYAGGRN
                     ALRDKQNVGLRGGANALLVGDYLTTIGSNIDDDKKMILGEGLIY"
     CDS             23965..24444
                     /locus_tag="ctg1_86"
                     /transl_table=11
                     /translation="MKIPTNLKHKPVIVSENYENVDGRYAYNTDTKGLSLGLAQWNDRG
                     KVDISAKVWRHTGDKWSRQSEELPLHRVLDLAILVCRAKLHFRESYKHEKLYDIENPII
                     DRVGLQGDAMTVAVCTENEKIDEDIQLFNQALSDDDELMGERLRTLSRILKEMGY"
ORIGIN
        1 tataaaaaac catattatat gtatacaaaa tatacatatt aatgatgata caattgaaaa
       61 atatattgat agtataaata aagagattag tagctgtgca gatatttaca agacaggaaa
      121 tatgattcta gatattatat taaatgaaaa gaaatcaatt tgtgataaaa atagtataga
      181 gtttatttca gatattaact tttcgatgtg cgattttata gatatggtag atgtatgcag
      241 tatattttct aacatattag ataatgcaat agaagcttgt gaaaagatag atagcaaaac
      301 tatagtcaaa tacataaaaa tcagaggcac catagttaat aaattttttg tcctaaaagt
      361 tgaaaattct aaaattaata atgttattat gaaaggcaat aaagtaataa ctgataaaag
      421 agattctttt ttacatggat taggaataat tagtataaaa agttcggttg aaaagtataa
      481 tggagaaatt gctattgaac acaaaaaaga caaatttatt atgaatatat atattccgtt
      541 gcaataaaag ttaaccagtt atacctaaaa aatgaccagt tgtacaaaat acattgaaga
      601 tattaatgga tgatgttatc ttaagcatga gaagatttaa aggagaagaa aatgattaaa
      661 tcatgtgcta ataaagtaac atctttttta gtttccaatg atgcaataaa tgatgaagaa
      721 tatgaagtgt actcatatgg atttgaaacg ttgttagctt ttataataaa tatatcggtt
      781 atattgttat taggattgat agtaggcaag tttgttcaaa ctttgttatt tttaacttgt
      841 tactgtccaa taagacaatt tacgggtggg tatcatgcaa atagttatag aaactgtctg
      901 ttagtatttg tatttatatt ttcaattaat ataattacat tagataaatt aagctatatg
      961 aatcttaatg aagttataat atgtacaacc cttataagtt atataggaat ttgtctttta
     1021 gctcctattg aacatagata caatccacta agtactagac aaagaaagag ttataaaaaa
     1081 gtggctatac ttttaactag tatagtgctc atatttgtat tattgggtat aaaatataaa
     1141 cctatttatg aatatgtatt atattcagcg tctgtattag tgtggatttt tataatgtta
     1201 attttagcaa ttataaaaaa aataaggagg gaataaagat atgaaaaaat atttaacttc
     1261 tatactaaaa tatgttggat ctatatcagc attcgcggta tcattatctg caaatacgac
     1321 atctacttgg atatcgcatc aacctaaagt tccagaagga gttagaaaat ttaaaaagat
     1381 taattaatat tataaaatag aaggtttcct tactatatat aagttgggaa atcttttatt
     1441 ttatttaaaa tctaatttgg actctctcat tttctataga tgggagacgg ctaacatcaa
     1501 ttcagtaaat actcgatgta tttataaaat tgaatatatg gagttgctat aggaaatgct
     1561 ctatagcata aaatactcaa gcattcgccc ttgtgtagtg agcgaaaacc aagccttgac
     1621 ctacacaagc atcgctatat aatcgcctat tgtggtggtt ctagccaaga acagaaactg
     1681 gtattattat aactgttgga ataataaagg tatctcggac aggattgcta cattggtagt
     1741 attgtccaag gagctcacac tcctgtagat gagagtagtt cacgagttgg agtcaagaat
     1801 ttaatcactt tattaaatca ttatattaga aaccaacctt ctaaagttgc tttctaatat
     1861 aatgtttgca gtagttatac ctaaatcctt tagagctctt ttaaatcttg atttacttct
     1921 aaatcatatc aatgtgaaaa gtatttgttt taatcataga tatcagtata gctatatatt
     1981 ttcagtataa atggaagtac agttttctta ttaaaagata ttaaaccata cgattacaat
     2041 aatttgttac tatcaaatta agtaccaatt aaccatatgt gaaggtgtgt aacaaccagc
     2101 catttatact taagagaaga ctagttgtac taaatatatt gaaaaataaa tatagaatgt
     2161 tatcctagat atgtgggata agggtttatt actataaaat tcatttttag tcttattaag
     2221 actaaagtaa gatgaaacaa ctttcataag gggtggggct acattatagt aaaaatatga
     2281 tatcaataac tttgtgaact aaatagtata gaataaaaag ctacttcaca ggatatcaca
     2341 gaaatcatta tatttttctt aataaaaaat gtttcttgct aggtgtcttt gcaagaaaca
     2401 ttttttatcc tctaattaaa cagctttatt ttttccagac actttatcta gtccaaattt
     2461 actatgaagt gcattaagag cctcaacacc tttaccttcc tctattatac aagagatttt
     2521 gatttcagat gtgcttatca taccgatatt tattcctaaa tcgtatagag tttggaagaa
     2581 agaagatgct atatctgcac ttccagctat accagtacct actatagata ccttaactac
     2641 agatctatca tatagtacct ctttagctcc tatttcttca gcaacttttc ttgtaacgtc
     2701 taaagcttcg ttaagttcat cacctttgac agtaaaagta atatcattta ctgaatttct
     2761 agttacgttt tgtattatca tatcaaagaa tataccatta gaagctaaag cagagaatac
     2821 cttaaaagct ataccaggtt tatcaggaac ctctataact gatactttag ctatatcttt
     2881 atctagtgcc acaccactta ctatcgcttt ttccatagaa ttcacctccg caatttctgt
     2941 cccaggatta tcatttagac tagatctaac tataagaggc atattatact ttctagctaa
     3001 ttctacggct cttgggtgaa gaacacctgc gcctaaactt gctaattcta acatctcatc
     3061 atagctaatc ttatctattt tgttagctgt actaaccaat ctagggtctg tagtatatac
     3121 accatcaaca tctgtatata tctcacactt tttagctcct atagatgatg ctatagcaac
     3181 tgccgaagtg tcagatccac ctctacctag agtagttata tcgttttttt catttatacc
     3241 ttggaaacca gctactataa ttatgtttcc tttactcagt tcacttttaa gtctttgagt
     3301 attaatctcc ttaatacgtg catttttatg cttacctgta gttaaaacac cacattgagg
     3361 tccagtaagt gagatagctt tgtgccctaa agagtttatg gccatagata gaagtgatat
     3421 agatatctgt tctccagtcg aaacaagcat atctaactct ctactagatg gatttagagt
     3481 tacttgcttt gctttctcta taagttcatc agtagtatct cccatagcgg aaaccaccac
     3541 tattacatca ctaccacttt ctttagtttt aataattctc tttgctacat taaatattct
     3601 ttccacattt cctacggatg ttccaccata tttttgaact attatatttt ccatctaaag
     3661 tccgttatgc aaaacctatt tgttcaatgc acttgatttt gccaaaagtt ttactaacgg
     3721 gattcactcc cttctataat atatttttat tacgatgtta tatattaacg ttctcgcttt
     3781 cgattcttaa atagcagaaa cttccctttg gtaaattaag tttagctatc atagactcca
     3841 tactttcaga atctattttt tctgttaata taactagttc gtgtcctgaa gatataacct
     3901 tatgatttaa tccaatatca ttaatactat ttaataactt atcactattt acattggata
     3961 ctctcatata gtaatttcct ttaaataatt tagaaccact tggttttata tcagtgttgt
     4021 tagtaaagct atactcttta tagttttcaa gaactatatc tagtatatca gtaactacag
     4081 catttgcagt aggattttta ccagcacctc taccatagaa ttgtagctcg tctactatgt
     4141 ctccctctat agaaacgatg ttgaaagcat cttttacact agcaaaagga gcagaatcat
     4201 ctacaagtaa tggctctaca gaagccgaac attcattacc agcaatagtg gcactcccaa
     4261 taagtttagg tacaagagat aaatctttaa agttttttat atctgaagca gatacagaag
     4321 ttatacctct acacacaaca tcatcaaaac ctacatgagc tccaaatcct aaagatgcta
     4381 atatagagat ttttctagca gcatcgaaac cttcaatatc atcagttgga tcagcttcag
     4441 catatccgta tttatgagct agagataaag cttcatcaaa acttaaatct tcatcataca
     4501 ttttagataa tatgaagttt gtagttccat ttaatatccc ttttatatta gaaacagagt
     4561 ttatttttat aatgtcttta aggcctttta taacaggtat accgccggca acactagcct
     4621 catataaaag tcctacgtta ttttcatcag ctaatttgtg aagttcatct aagtatggtg
     4681 agataactgc tttattagct gtaactacat gtttaccact tctaagagac ttaatgatat
     4741 attcataagg tagttctata ccacctaaaa cttctactaa tatatctatg ctagagtcgt
     4801 ttaaaatgtc atccacattt tcagttaaaa tactaggatc tacacctaaa cctctatctt
     4861 tgctcttatc tctaactaat attttagata tctcaatatt ttttccagta gcttttttta
     4921 agctttcctt tttatctctc aatatttcat aaaccccaga acccacagtt cccagaccta
     4981 ataaaccaac cttaaccatt accaataacc accctttcgt atataattta ttatccgata
     5041 ttaaaaacct agcgcataaa ataaccactt ttaaatagtt ttcgttaatt aaactttata
     5101 tatcaaagca aatgaacccc gcttagtcac tacttaaata tttcaaagtg taattgtata
     5161 aaaaacactt gtgtttcact gaaaaacatt atatcatata atagacatta atcaataggt
     5221 tttataaata tttttaaaaa aatactcgga ggtaatagat atgagtttat attataaaag
     5281 tactagagga gacagtgaaa aagtaaattc actagaagca atagttaaag gtatagcaaa
     5341 tgatggaggt ttatatgtac cttcatatat agaaaaaata gatatgagct taaatgaatt
     5401 atctaaaatg aactatcaag aattagcata ctatattata aataaattct ttccagactt
     5461 tagcgaggaa gagcttaaag actgtgtaaa tagtgcgtat gatgaaaaat ttgatactaa
     5521 agaaatagca ccaatagtag aaaagtcagg agcttatttt ttagagttat ttcatggtcc
     5581 aacattagca tttaaggata tggcactttc aatactacct tatttattaa aaacatcagc
     5641 tacaaaatta gactatttaa aagagatagt aatacttaca gctacttctg gagatactgg
     5701 gaaagctgca ctagaaggat ttaaagatgt agatggaata aagataatag tttattatcc
     5761 agaaaacgga gttagcgaag tgcaagaaag acagatgata actcaagaag gaaaaaacac
     5821 ttatgtagtt ggaataaaag gaaactttga tgatgctcaa agtggagtaa aggaagcctt
     5881 taacaataga gaatttaatt tagatttaga tagtgaagga tatgtattat cttcagcgaa
     5941 ttctataaat ataggaaggc tagttccaca agtggtatat tacttccacg gatatataga
     6001 gcttttaaga agtggtaaga taaaagaagg agataaaata aacgtagtag ttcctacagg
     6061 aaactttgga aatatattag cagcctttta tgctaaaaaa atgggcttac ctataaacag
     6121 atttatatgt gcatctaatg agaataatgt actatcagac ttctttaaag atggtgtata
     6181 tgatagaaga agggaattaa agcttactaa ttcaccatct atggatatat tgatttcaag
     6241 taacttagaa agactattat atgaattaag cggtgaagat gatgagaatt taaaagaact
     6301 tatggataaa ctttcacaag atggtatata tgaagtttcg gatagaataa aagttggatt
     6361 aaaggatttc tatggtaact ttgcaacgga agaggaaaca cacagtgcaa tatcaaaagt
     6421 atacaaaggt acagattatg taatggatac tcatactgcg gtagcttatt ctgtatatga
     6481 aaaatataaa gatgaaacag gagacaatac tcctacaata atagattcga cagcgagtcc
     6541 atttaagttc acaagaagtg ttagtgattc attaggaata gagatagaag gtaagaatga
     6601 ctttgaactt ataaaagaac tatctaacaa gactggacta ataataccaa attctataaa
     6661 ggatttagaa actagagaaa tcttacacaa aacagtttgc aataaggatg agataaaaga
     6721 agctataaaa aaatattaaa aagttaggtg aaaatttatg atagaggtta tagtaccagc
     6781 aacaagtgct aacatagggc cgggctttga tactttaggg attgcactca atatttacaa
     6841 caagtttaca gtcgaagaaa tagaggcagg attaataata gaaggttgcg aagagaagta
     6901 tgcagatgaa agtaatctag tataccagtc tatggttaag tgctttgaaa aagtaggata
     6961 tgagccaaag ggaataaaaa tatctataga aactgatatt ccagtatcaa ggggattagg
     7021 aagtagcgct acttgtatag taggcggaat aatagctgct aatgaattag ctggatctcc
     7081 cttaaataaa aagaaaatac tagaacttgc aacagagatg gaaggacatc cagacaatgt
     7141 agcacctgca ctatttggag gaatgattac ttccgtatat gacgaaaaag tttattatag
     7201 taaagtaaat atagcaaaag gattaaaatt tttagccctt ataccaaact ttaaactatc
     7261 tactaaaaag tctagatcgg tactcccaaa agttgttcct catagtgatg ctatattcaa
     7321 cgtaggaagg gtagcactta tgatatcagc attacaaaac ggagagtttg atttattaaa
     7381 gataggtggt caggataaat tacaccaaca atatagaggt gctttaatag acggatatga
     7441 cataatactt gaacattgta aaaatatcgg agtaaaagga gtatttctaa gtggagcagg
     7501 cccaactata cttgtagcag tagaagaaga tgataatgaa acttataaag agataaataa
     7561 aattcttgat acattggaga ataaatggga gataaaagaa ttaagtatag actataaagg
     7621 agctttcttt aagaaagttt agattaaaga taggagtaga gtataatatg tattctatag
     7681 aaagtaagta tctagtgata gataaagata tacttcctga tgtatttgag aaggtattat
     7741 tagcaaaaga gcttttaaga acaggtgagg ttaaggagat aacggaagca gttaagaaag
     7801 taggaataag tagaagtact ttctacaaat ataaagatag tgtatttacg ttagatgaaa
     7861 gatctatggg taagaaagtt acactatctt tcttattgag tcatatgcaa ggggtattat
     7921 cgaatgtatt acaaactata tctgctaacg gcgggaatgt attaactatt aatcaagaca
     7981 ttcctataca tgatgtggca aatgtaagca taacttttga tgttagtcac ataaagataa
     8041 gtatagagga agtaatagaa gaagtaaaaa gtatagaagg ggttcaaaag ctagtagtag
     8101 ttactatgga gtagtctcaa caatacaaag ggggagtgaa atgaaacaaa aaaggttagt
     8161 tgcattaggg gtatttatac tattacttat tttaaatact gcgtttagta gtgtagaaaa
     8221 tagtatttac acttctaaag gagaatggta tgaagagata cacactcagg gttcgattga
     8281 acaattagca ctgttagaag ttgacggaat tattcaagac actgggtctg gatatgcagg
     8341 acttggaact aattataatc atcagacatt tttaaaacaa cttgagtatg cttttgaaaa
     8401 tgaaagtata aaaggagttg ttttaaaagt aaattcacct ggaggtggag tattagagag
     8461 tgatgaaatt catagaaaaa taagcttgct gaaaaaagaa cataaaaagc cagtagtagt
     8521 atatatggac ggggttgcag cttctggagg atattatatt tcagcacctg cagataaaat
     8581 agttgcaaat agaaatacta tgacaggttc acttggagtt ataatggaag ggacaaatta
     8641 tcaccaactt gcagaaaact atggggtaaa aacagatgtt ataaaaagtg gggcttacaa
     8701 agatatattt agtcctatga aagagatgac ccctgaagag cgagcaatat tacagtcctt
     8761 agtagatgaa agttatcaat tctttgtaga tgtcatatct gaaggcagaa aattaagtaa
     8821 ggaaagagtg ctagaaatag ctgatggaag aatttatagt gcattacaag caaaagagtt
     8881 aggattaata gatgaaatcg gatacttgga agatgctata tctagtgctg ctaagctttc
     8941 aaatgcagat aatcctacag tcgttaagtt taagcaacct aagtggtccg catttgacac
     9001 tgtatttagc tatgtatcaa aatactataa taagtcatta ggaactaata tgatagaaat
     9061 agataaattt acgaaatcag accgtccaaa gctaatgtat ttatggattc aataaggggt
     9121 ggtaatcatg aggacttata gattagcagg attttggact agatttttgg cttatatgat
     9181 agatatttta accattgtat caatatccgg aataatatta agaggttatg ctaaggagat
     9241 tcctttctta ggcataagta tggtatctat tggtataatt ggctttatat attttacagt
     9301 aatgactaaa ttgctaggtc aaactctggg aaaaatgatt atgggaataa aagtagttag
     9361 aatagacaat aaagagttag actggataac acttgtatat cgtgagggaa ttggcagatt
     9421 tatatctcag cttttaggac ttcacttagg gtatatatgg tgtggtttca gtcctcgaaa
     9481 acagacctgg catgatagta taagcgatac atatgtagtt tttatagatg aactaacttg
     9541 taagcatatg atcgaagttc aagagtagta tcttgaccta aatgtaagga ttgaaataag
     9601 cgtgttaata aattaacaat agttgaaaat ataaaagata tattataaga taatggtgaa
     9661 ataagaaatg taatatagaa ccagatgaag atagtgtgag atatctattg gagatagccg
     9721 aagaagcaat ataaaagtat gccaactttt atagaaactt tcaggcaaaa ggaacgctat
     9781 tggatgggtc tctgaagaga tcgatgtaaa tcgacaccga aggagaaata cacttatgtg
     9841 tagaagctct caggtttgaa aacagaggaa tatataggca gcttaattta cgcgcctcta
     9901 tattcctttt tttataacat agcatgaaat tctgtattta cataataatt acagaagagt
     9961 gggctaaaaa tacacaaaaa tataaggagg taatattata atggctaaaa gaacagctct
    10021 ttatgaaatg cataaaaaac acggtggtaa attagtagat tacgcaggat gggaactatc
    10081 aagtgacttc gcaggactag gacttgtagc agaacatcaa gcagtaagaa atgcagtagg
    10141 tgtattcgat gtttctcaca tgggagaaat cgaaatcaaa ggaccagaag cgtctaaatt
    10201 tgctcaatat ttaatgacaa atgatttaga ttcaatagga gacggtcaag ttatatatac
    10261 ttacttctgt tatgaagacg gaggaatagt tgaagactta ctagtttaca aacgtaatga
    10321 tcaagattta ttattagttg taaatggtgc taacatagat aaagacgttg aatggataaa
    10381 ccaacacgct tctaaatttg atgttacagt tatagatagc tcaccacaaa tatcagaagt
    10441 agcagttcaa ggaccaaaag ctcaagcaac tcttcaaaaa ttagttaact ttgatttaga
    10501 tgaaataaaa ttcttccact tcaaagaaga tgtagacgta gctggagtaa aatgtatagt
    10561 atctagaact ggatatactg gagaagacgg attcgaagta tactttgcaa atgatgattc
    10621 aattaaagtt tgggaagcag tatttgaagc tggagaagaa tttggaatac aaccagcagg
    10681 acttggatgt agagatacat taagattcga agctaactta cctctttatg gaaatgaatt
    10741 aacaaaagat aattcaccat tagaagctgg atacggtttc ttcgttaaag tgaataaaga
    10801 aagcgacttc ataggaaaag cagctcttca aaaacaaaaa gaagaaggat taaaaagaaa
    10861 agtagttgga ttcgaattag tagacaaagg aattccaaga cacggatacc cagttgaagt
    10921 aaatggtaaa gaagtaggat atgtaacaac tggatatgca gctccatcag taggaaaaac
    10981 tataggtatg gctatggttg atatagaata tactgaatta ggaacagaat tagaaatagt
    11041 tataagaaag aaaaaagcta aagcgaaagt tataagcaga aagttcttag aaagacacaa
    11101 taaatcaaaa taatactgtt ataataaatt tgttgagtta gagttgcgct tatagcgact
    11161 catttgctaa aatgattatg cagtaaaaaa aaatacaaac caaacattta aggaggattt
    11221 taaaatgagc aaaatagtag aaggattatt atattcagaa gaccacgagt ggataaaagt
    11281 agaaggaaac gtagtaacaa taggagtaac agatcatgca caagatcaac taggagaaat
    11341 agtatacgta gaattaccag aagttgacga tgagttcaac gctggagatg cattcggagt
    11401 tatagaatca gttaaagctg catcagactc attcttacca gtatcaggaa aaatagtaga
    11461 agtaaacgaa gctttagatg acgaaccagg actagtaaac gaagacgctt acgctaactg
    11521 gatagtaaaa gttgaattat cagatgcttc agaattagat tcattaatgg atgctgcaaa
    11581 atacgaagca ttctgtgcag aataatataa attataagat atagaattct tatcttctat
    11641 tgaaataaga tagaagataa gaatttataa tgtgcttaaa tatatagata aaacgtaatg
    11701 attaaatctt aaacggaggt gtaactatgc atagatatat acctaacact gatgctgaga
    11761 aaaaagaaat gcttgatagc atcggggtaa gttctatcga agacctattc agtgacattc
    11821 ctagtgattt aagattccaa ggagacttaa acattggtaa aggactgtca gaattagaag
    11881 tagtaaaaca catgcaagat cttgtaagta aaaacaaaac tacagaagag ttaacttgtt
    11941 tcttaggagc aggaacttat gatcactata taccatcaat agtaaaacac ttagcattca
    12001 gatcagagtt ctatacagca tacactcctt atcaaccaga aataagtcaa ggaactctac
    12061 aaatcatatt tgaataccaa tcaatgatct gtaacttaac tggtatggac gtaactaatg
    12121 cgtctatgta tgatggacct acagcttgtg tagaagctgc aatactagct tgttcagatg
    12181 cgaaaaaaga taaaattata gtatctaaat cagtaaaccc tgaaactaga gaagttctaa
    12241 agccttattt acatgctaga aacttagaaa tagttgaagt agacactgaa aatggtgcta
    12301 ctaatcttga acaactaaaa tctttagttg atgaagacac agcaggagtt atagtacaaa
    12361 gccctaactt ctttggtatc atagaagatg ttgaagaagt agaaaaaata actcgtcaag
    12421 ctaaaaaagc aaaattaata atgtacacag atccaatatc tttagctgta ctaaaatcac
    12481 ctaaagacat gaacgtagat atagtagttg gagatgctca agttttaggt agccctatgg
    12541 catttggtgg tcctcatata ggtttcttag cggttaattc taaattagtt agaaagatac
    12601 caggtagaat agtaggacaa acagaagatg ttgatggaaa cagagctttc gttcttactc
    12661 ttcaagcaag agagcaacac ataagaagat acaaagctac atcaaatatc tgttcaaacc
    12721 aaggattaaa tgcaattatg actactattt accttacaac tatgggtaaa gaaggactta
    12781 gagaagttgc attacaatct actcaaaaag cacactatgc atttaacgag ttaactaaga
    12841 gcggtaaata caaacctcta ttcccaggtc aatcattctt taaagagttc gcagtaacta
    12901 gcgataaatg tgctaaagaa gtaaacgaag gacttcttaa agaaaacatc ctaggtggat
    12961 atgagttaag taaagactac agtgaacttg caaacggttt acttctagct gttactgaaa
    13021 agagaacaaa agaagaaatc gacaagctag tatctgctat ggaggtgtta taacatggcg
    13081 aacaaatacg ataaattaat atttgaagtg tcaaaagaag gtagcaaagg atatagttta
    13141 cctcagttag acgttgcaga agttgaatta agtgatataa ttcctagcaa atatctaaat
    13201 gaaggtaaaa ttgacttacc agaagtagga gagtttgaag tagtaagaca ctttactaac
    13261 ctttcaaaca aaaaccatgg actagatgca ggattttatc cactaggatc atgtactatg
    13321 aagtacaatc ctaaaataaa tgaagatatg gctggattaa gcggatttac aaacatacat
    13381 ccatatcaat cagaagatac agtacaaggt gcattagaag ttatgtataa ccttgatgag
    13441 aaactttctg aaatagcagg tttcgcaaga acaactcttc agccagcagc gggttcacat
    13501 ggagagtata caggactttt agttataaaa gcataccatg agaaaaacgg agatactcaa
    13561 agaactaaaa taatagttcc agattcagca cacggtacta acccatcttc agctcaagtt
    13621 gctggatttg atataattga aataaaatca aataaagatg gttcagttaa cgtagaaagc
    13681 ttaaaagcag ctttagaaaa caaagaagaa atagcaggac taatgcttac aaacccaagt
    13741 acattagggc tatttgaaag aaatataaaa gaaataacta gcttagtaca tgaagcaggt
    13801 ggactaaact actatgatgg agctaacatg aatgctatca tgggtaaagt aagacctgga
    13861 gacatgggat ttgacgtaat gcactataac ttacacaaaa ctatgtcaac acctcacggc
    13921 tgtggtggac caggagcagg tccaatagga gtaagagaag acttagttga attcttacca
    13981 actccagtta tagagaaaaa agatgacaaa ttcgtattag actatgatag acctaactca
    14041 ataggaagta tcaaaggata ctacggaaac tttagtgtat tagtaagagc atacacttat
    14101 atattaacta tgggagctga aggattaaga gaagctagtg aatcagctgt attaaatgca
    14161 aactacatga tgaacaaact taaagaagat tactatttac caatcgacca agtttgtaaa
    14221 catgagttcg tattaggtgg actacaagac aagtcaacag gagttacaac tatggatgta
    14281 gctaagagat tacttgactt tggataccac ccaccaacag tttacttccc attaataata
    14341 aacgaagcaa tgatgatcga accaactgaa acagaaagta aagcaactat ggatggattc
    14401 atagaaacat taatcacaat agctaaagaa gctaaagaag atccagacaa actacacaac
    14461 gcaccgttta ctacacaagt aagaagagtt gacgaagcta aagcggcaaa agatctaata
    14521 ctaaaatata caaagtaata aaacaggggc tatcgtaaat gattggcccc ttttttattt
    14581 tagaaaagag gataattatg gaactaaatg tactatctct gggaaaatat aattatgaaa
    14641 aaagtttgga acttcaattt gatcttttaa aaaaaagaca agaagataag ataaaagata
    14701 cattaatatt ggtagaacat ccccatgtta taactctagg aaaaaatgct cataaagaaa
    14761 atatattagt ttcaggtgaa catctaaaaa agaatggaat agatttggta gaaataaata
    14821 gaggtggaga tgttacctat catgggccag gtcaaatagt aggatatccc ataataaata
    14881 taaaagaaaa gaaaatggga ataaaagatt ttgtatctaa attggaagaa gtttttatag
    14941 cgttattaaa tgaaaaatat ggtataattg cgataagaga taatataaat aatggcgtat
    15001 gggttgataa gaataagata gtggcattag gattggctgt gaagagatgg gttactatgc
    15061 acggttttgc atttaatgtg ggtactgatt taaacttttt caatcttata gtaccttgtg
    15121 gagtacaagg aagaggtgtt actactgttg aaaaactcac aggaaaagaa gtagatcttg
    15181 aacaagaaaa gtcagaccta ttaagatact ttatagaaat atttaattac actagtataa
    15241 aagaagtaac tatagatgat ttggaggtat agtcatggca gaattaaaaa gaaaaccaga
    15301 atggcttaga atagaaaaga gaaaaggaca aaacttagga tatgtaaagg gattgctaaa
    15361 caaactatct ttaaatactg tatgtgaagc cgctaactgt cctaatagag cagaatgttt
    15421 tagtaaaaag actgctacat ttatgatttt aggaagtgaa tgttcaagaa actgtaagtt
    15481 ttgcaacgtt acacatggaa aactacaaga accagatcct aatgaaccag aaaatatagc
    15541 taaagctaca gaagaattag gactaaaaca cgttgttatt acttgtgtta caagagatga
    15601 cttaaaagac ggtggtgcag gacatttcgc taagacaata gaagagataa gaaaaagaaa
    15661 taatgatata ataatagaag tattaatatc agatcttaag ggaaggatag aagatcttaa
    15721 agtaatagta gatgctaacc cagatataat aaatcataat gtagagaccg ttcctagctt
    15781 atatgataag gtaagaccta tggctatata taaaagatct ttagatgtta taggaaatat
    15841 taagaaatta aatcccaaga tattcacaaa atcaggaata atgcttggtc ttggagaaac
    15901 tgaggaagaa gttatagagc tatttaagga tctaagagaa gtagactgcg actttttaac
    15961 tgtaggacaa tacttacctc catcatcaaa acatgtagaa ttaaaggaat acattactcc
    16021 ggaacaattc gataaatata aggaagaggc gcttaaacta ggatttaaat ttgttgcatc
    16081 tagcccacta gttagaagtt cttataaagc tgctgatatg ctagaggctg ctaagtaaag
    16141 aacaaaggtg tgttaaaagg aaagggaatc ttttactatg aataaaggtt ctcttttctt
    16201 ttaacagctt gaaaatttaa attaaggaga aataaaatga taaaaagaat tttttcagtg
    16261 gtcatattat caatccttac caccatagtt tcaggatgtt ctattaatgg atctccagaa
    16321 gatttgatga gacctcctaa actggaaagt aacagggaac aagttaaagt agcactacaa
    16381 gagtatttac ctcagaatgc aaaactagtt attcctccaa gtaatgataa accaagtgct
    16441 ataaagtttt tagatttaga tggggatgga aagagagagg caatcatttt ttataattta
    16501 gatttagatg aaaatccatt aagggcatta attttaaaaa atgaaaataa gaaatggaac
    16561 aataagggtg agctcaaaat attaggacag gatttagata aagtattttt taaagatata
    16621 gatggagatg gtggcttaga tataattata ggatctaagg taagatactc tttatctaag
    16681 aatttaaata tatatagttt taaaaatgga aatatcgatg agcttcttga aagtacgtat
    16741 gagcatttag tagtagaaga tttaaataat gatggactag ctgaaaccat tcttttaaaa
    16801 tcgaataaag aacaaaagca agtgcgtgga gagctatata agtataatca aggaaaagta
    16861 gaaatgatgg atgaagtaaa ttttgaaaat atctctgaga ttaactctat aaaagaagga
    16921 tatataggcg aaaatactca gggtgtagta ataagcacta caggtattga taagttatta
    16981 aaaatatata tattaaaagc tgaggataat agtttagtaa atgtagtaga aggtggcttt
    17041 atagaaagtg aaaaagtacc taatatagaa tatgtactac ctcaagatat agataaagat
    17101 ggaataatgg aatttgctat tccaaaggta caaaaacgaa atgatgaaca aattgaaaat
    17161 cctactagct ggttaacaga gtggtattca tgggatggtg ataagtctat agtactgaag
    17221 aaaataaact attatgatga aatttcaaat ttttcttttg acttcccact gacatggaga
    17281 gaaaatatta ttgtaactaa ctcaaaaaag gatacaaaca ttataagtga tgaagaatgg
    17341 attaaagtag actatagaga taatagtgaa aaacctaagc gatatcatct atttacaata
    17401 tatatatata cagatgaagg acttaaaaga aaagatcata gtaaaaataa agaagagcct
    17461 gtgaagattt tagaggacat agataagaat tacttcatag ttttaggaga tgacattaag
    17521 aaagaaaaaa taaaaaatta gtgaagaagt tgataaaata atcgaaagct ttaaaatttt
    17581 agagcgatag gctaggaggg tttaggaatg tctagaatat tagtattaga agatgaagat
    17641 gatattaggg cctttatagt tataaatctt aagagggctg gttatgaagt actacaagct
    17701 gcaacaggag aagaagcatt agatataatt tctacagaaa aaaatataga tatttcagta
    17761 ttagatgtca tgttaccagg aattgatgga tttgaagttt gtagacaaat cagagataaa
    17821 gacaaaacta tgggaatagt aatgcttaca gcaaaggcac aggagttaga taagataagt
    17881 ggtctttcta tgggagcgga cgactatata ttaaaaccat ttagtccagc agaattaact
    17941 gctaggatag atgcattggt tagaagagta gacctactca aaggtaaaag taatgacatg
    18001 aaaaatgcat cttcaggtcc atttactata gacacttcag ctagagtaat attaaaaaat
    18061 aatcgtgaga tagatcttac tcaaatagaa tatatgatta tgaagctttt tatagaaaat
    18121 gaagatcaat cattaactag agaagagata ttaaaaagtg tatggggaaa agactactat
    18181 ggagatccta aaatagtaga tgtaaatatt agaagactta gaagaaagat agaagataat
    18241 ccttctgatc cgaaatatat aagaactgtt tggggatatg gatatagatg gagaaaggaa
    18301 gaagattagc ttgcaaggaa taaaaagaag atgggtgtac aactatatac ttataatttc
    18361 aagtgtactt ttattactag agggcgcatt tatcatattt ataaaaaact attattacga
    18421 tagcatatca caaaatttat ctaataaagt taatacagcc acagactttt ataataaata
    18481 tttaaataat aaactagata cagtaggtaa tatagcagaa cagttagtta aagattttgc
    18541 tcataaagag caattagaac ttcaaattat agatacagaa ggaaatatag ttatgagctc
    18601 tagcgggttt gtaatgtatg aaaaagtaac tacaggagac tataaaagtg caataaaagg
    18661 acaatcttca aactggactg gaattaataa agagaccggg gaaaaaataa tgagtgtatc
    18721 tagtccatta aagcaaggaa aaaataaagt tgtaggggta gtaagatata taacatcact
    18781 agaagagaca gataacgtaa ttaaaattct aatagcaagc tctcttatat ttatatttat
    18841 aatgcttttc ttaatgcttg tgctgagtat gatatttagt aaatcaataa taaatccgtt
    18901 aaacgaatta aatgaggtag caaaaaaaat ggctcagggt caattctcag agagggtaga
    18961 gaagcggtat aacgatgaaa ttggagagtt atcggatact ctaaattaca tggcgggaga
    19021 aatagttaaa actactcagc tcaaaaatga atttatatct tcaatatcac atgaactaag
    19081 aactccttta acttcaataa aaggatgggg agagactata cttactggag gtctagaaga
    19141 taagtatgaa gcagaagtag gacttaaaat aattataaaa gaaactacta gattagcaca
    19201 aatggtagag gaattattag acttctcaag aatagaaagc ggaagaatat ttctacattt
    19261 gcaacagata gatatagtaa gtgagttgag tgatatagtt cacataacta agcttagagg
    19321 aataaaagat ggagtaacgt tagaatatac tcatcaagaa gagattccag aaataatggc
    19381 agaccaaaat agattaaaac aagtatttat aaatatatta gataatgcaa ttaagtttac
    19441 tgatagcggc aaaaaagttt atgtagatat atattcagat gaagagaatg taataattaa
    19501 gataaaagat gaaggtgcag gaataaatga agaggatctt ccaaaagtaa aagaaaagtt
    19561 ctacaaagga caaagtaaaa agtcgggaag tggtataggg ctagcagtat gtgatgaaat
    19621 aataaagttg cataatggaa cactagatat agaaagtaca ttaaacgtag gtacagttgt
    19681 tactataact ttacctttga ttactgaaag ttaatattaa aaggttgtgt caaatatgca
    19741 taataaaatt caaattggag agatggctaa actacacaat atatctgcac aaacgttaag
    19801 atattacgat aaaataggtt tactaaagcc tgaatatatg gacaaagata ataattatag
    19861 atactacaat atagagcaat tcgcacacct tgactcaata ctatttttaa aagagttagg
    19921 tatgagtctt gagcaaataa aagaatattt taaaaaaaga gatatagaaa gtgtactaga
    19981 actactgaag caaagggata gcgatatcga gaaacaaata aaattattga aaagaagaca
    20041 aagaaacctt caagataagg tatctatgat agagctctat atgcaaaaaa aagaatataa
    20101 taattatcaa ttaaaagata taccttcaag aaatatggtg catttaaaat ctaagcttag
    20161 taaaagtaag acagattttg aatatggctt aaaaactctt agtaagctaa ttggagatga
    20221 aatatacttc tttaatagta tgataacatg cgttatagat aaaaaaagta tagaaaaagg
    20281 tatatatgat tattggagct ctataggttt actatttagt gaacatttac tagagaatga
    20341 aaatatagaa actataccag ctggtaaata tgcaagtata gtatatgggg gaaactacga
    20401 taaaggaaaa gagtactatg aaaagttgtt aaactggata aaagaacata acttacaagt
    20461 agtaggcgat agtttattaa ttactataac ggattctgta ttttcggact ttgaagaaga
    20521 gtatataaat gagatacaga ttcctgtaaa aaaatattga cattatagtt actataacct
    20581 ttaaaatgtg aattagtata ataatattct agaggtgaag ttatatgagt aataaagtag
    20641 atttattaaa cgatgatgtc cgtaaaactt tttttaggta tttgataccg agtataggtg
    20701 gaatgctagg tacttcacta tatgttttag cagatactat gtttgtagga agaggaatag
    20761 gaagccaggg attggcggca ctaaatatct ctatacctat gatgaatgtg tttaacggat
    20821 taggactttt atttggaatc ggaggggcaa cagctctttc cataagtagg ggacaaaacg
    20881 atgaagatca agtaaatcat atttttacta aggctatgtt gatggctggt ttgctaggaa
    20941 taatatttac aatagttcgt atattttttt tagacgaact atgtacattc ttaggtgctt
    21001 caggaacaac gcttcaaatg gctaaggatt atctaggagc tgttatgtca tttagtatag
    21061 catttttatt aaatagtgct cttacagtgt ttgtgcgtaa cgatggagca cctaaattgg
    21121 ctatgtgggg tatgctttca ggtagtatag cgaatgtaat actagactat gtattcatat
    21181 ttatatttgg ctggggaatg tggggtgcag ctgttgctac aggaatgtct ccagtgataa
    21241 gtttagtgat actaagtacg cactttatta gaaaaaataa tactatcaag attattaaaa
    21301 caaaattaca attaaatata ttgaaaagaa tagttgcaaa tggtggttct agctttatag
    21361 tagagatttc atcaggtatt gttatatttg catttaacaa tgttatactt gacataactg
    21421 gagacattgg tgtatctgct tatagcatta ttgctaacct gtcactagta tgtacagcta
    21481 tattcacagg tataggtcag gcaatacagc ctattgttag cataaactat ggtgctcgta
    21541 aaattgagag agtttatgaa tctgctagga tggctatata ctgggcattg ggtcttggtg
    21601 ttgtatttta tatgatagga atattatttc cgaatgctct tatctcaata tttaataaag
    21661 ataacgcaga acttgcggat ataacatcta ggggaataag actgtatttt atagctttta
    21721 tatttatggg actaaatata gttatggctt catatataca gtctacagaa caggcaagaa
    21781 cttctatgat aatttctctt tctagaggat ttatttttat aattttattc ttagcaatac
    21841 tgccaaaagt atttggtata gatggggtat ggttaacact acctttagca gaaattatga
    21901 cagtaatatt gtcagtagta tgtttcaaga gttgcagaga cgctatttct tatagtataa
    21961 agaaaaagag attaatggtt aaataaacta aagagtctat caaataaaaa aatcatgatt
    22021 ataatattat aatcatgatt tttttatttg ataagaaatt aaagagttaa gtttaataag
    22081 tattatctta aagcaattgt caactatatt gttaacatat gaaaataatg agttgacaat
    22141 aatgcggatt taatataaaa taaagaaaat ttaataaagt gaaagtcaat ttaaaagatg
    22201 aaattattta aaaatgaatg aaaggggaaa gtttaatgaa aataaataca agagatatga
    22261 tacttatatc tatgtttgct gctctcacag ctataggtgc acaattaagg ataccaacag
    22321 agccaatacc atttacgtta caagtactat tttgtatgta ttcgggaata ttattaggat
    22381 ctaaaaaagg agctttttct caaatattat atgtattact aggacttgct ggacttccta
    22441 tctttgcaga aggaaatggt ggcccttcaa ttataattag ccctacattt ggttacttac
    22501 taggatttat agcttgtgca tatgtttcag gtaagattac agagaacttt aaggacgtga
    22561 acatttttaa gatagctttg gcaacagtgt caggcttatt agtagtttat atagttgcag
    22621 taccttacct ttacttaatc ttaactaaag taatgaatag tcctacaaca cttaacggag
    22681 tagtaaaaac aggattttta gcattcttag gtcaggattt agtgaagtgt gctatagttt
    22741 cagctacttc agtattaata attccagcac taagaaaatc aggatactta gaagtgaaaa
    22801 aggaagctgt acattaatat gaaaaatttt ataaatcaaa ttaaaaacaa agtattagaa
    22861 ggtagtaata tagactataa ggaagcgttg aagcttataa gtatagataa tggtgacata
    22921 gataacttaa aattgttact ggatggagca gatcaaataa gagaaaaata taatggtgat
    22981 aaagtagaca tgtgtagtat aatgaatgct aaatcaggga aatgttctga agactgtaaa
    23041 ttctgtgccc aatcaggtca ttatactaca ggaataaatg aatattcatt aataaattat
    23101 gatgaggcat atcagagggt tagcgaaatg gagcaaaagg gagtcgatag attttcacta
    23161 gttacaagtg gaaaaggagt aacggacgaa gaatttagta atctactaga catttatgga
    23221 aagttgaatg aaaacaccaa tataagttta tgtgcttctc atggagtaat atcatatgaa
    23281 caggctaaga aattaaagga tactggaatt aatatgtatc atcataatat agaaactagt
    23341 aagaattatt ataatgaaat atgtaccact cattcttatg aggaaagagt gggaactata
    23401 agaaatataa agagtgctgg aatggaagtt tgttgtggtg taattattgg tatgggagaa
    23461 agtatagaag atagattaaa tatgatgttt gagataagag acttagaagt agattctatt
    23521 ccagtaaatg tacttaatcc tataaaaggt actccattag agaatctaga aatactagag
    23581 cctatggaga tattgaaaac tatagcagta tacagatata tagttccaaa atctcatata
    23641 aggtatgcgg gagggagaaa cgcattaaga gataaacaaa atgttggatt aagaggagga
    23701 gctaatgctc tactggtagg agactactta actaccatag gaagcaatat agatgatgat
    23761 aagaagatga ttttagggga agggttaata tattaaaaat aaatataaga tttatataaa
    23821 atttaaagaa cctatttaaa aggttctttt ttattgtagt ttgctcttaa catataaata
    23881 attgacaaaa ctaattaata gtaataaaat gaatttagta aattagtaat ttagtaaatt
    23941 actaaaaata aggaggtagg aataatgaaa ataccaacta atttaaaaca taaaccggtt
    24001 atagtgtcag aaaactatga aaacgttgat ggaagatatg catataacac ggatacaaaa
    24061 ggtctttcac taggacttgc tcaatggaat gatagaggaa aggtagatat ttcggctaaa
    24121 gtatggagac acacaggaga taaatggtct agacaatcag aggagttacc acttcataga
    24181 gtacttgacc ttgcaatact tgtttgtaga gcaaagcttc actttagaga atcatataaa
    24241 catgaaaaac tatatgatat agaaaatcct attatagata gagtagggct tcaaggagat
    24301 gctatgacag tagctgtatg tactgaaaat gaaaagattg atgaagatat tcaactgttt
    24361 aatcaagccc ttagtgatga tgatgaactt atgggagaaa gactacgtac gttatcaaga
    24421 atattaaaag aaatgggata ttaagctgat ggatagaaaa aagaattgaa agaacaatat
    24481 aagcaaatga ggcctgatat gggaatagtt attattaagt ctagtactga taataaat
//
