LOCUS       NZ_CP101638.1          17360 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP101638.1 Terrisporobacter mayombei strain DSM 6539 plasmid
            pTM1, complete sequence.
ACCESSION   NZ_CP101638
VERSION     NZ_CP101638.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:35:51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4525
            Orig. end    :: 21885
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17360
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14525:20757]"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..16232
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
     cand_cluster    1..17360
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /kind="single"
                     /product="proline2aminovalerate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17360
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="proline2aminovalerate"
                     /region_number="1"
                     /rules="(Proline_reductase and (Pro_racemase or GRDB) and
                     not ACP_syn_III_C)"
                     /tool="gutsmash"
     CDS             complement(1115..2080)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="LGNLPKFHDENLLVGIETSDDAAIYKVSDDLALIQTLDFFTPIVD
                     DPYLFGQIAAANSLSDVYAMGGEPKTALNIVGFPNCLDPKILGRILEGGASKVMESGAI
                     LAGGHSIQDDEPKYGLSVTGFVNPEKIFKNYGSKPGDVIILTKQIGSGLINTAIKADMA
                     EQSQIDEVVTVMTSLNKKAKEVIENYNISACTDITGFGLAGHAMEMASSSKVTFEIDVK
                     KVPYIDGAIEFAKMGLVPAGTYNNKDYISNDVNSENIEESFIDVLYDPQTSGGLLITLP
                     ESEVENIIKDFENKNMDTKVAIIGKVIEKQEKSINLVKNL"
     CDS             3522..4328
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="CbiA (E-value: 1.9e-17, bitscore: 53.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIVSFFNVKGGVGKTTLTILSAIALSKEGSRVLIIDADTQANLT
                     QFLYKVSHSDKTMFDGLADNLSAEELIIKSPCERYKNIDIIPSDLSLSVLSEYLTTKTN
                     REKSVWRWFKSNVNALGDYDYIFVDLSPSYDLIARNFMLCSDSIITPIAYQDIASIRGC
                     ELFYLKYNQDLEDMEMENMAKRAVVINSYTSRKLSTGDIFLEKLNEFEHIKKDLINAKI
                     SDTTVIKNAILSKLDIDDYCRKIKKSHKVREEFKEVINELKERDVL"
     CDS             4328..4732
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="VGLDKFLKDDKKEELILTKKDYKSKVNHIVKNTFEKDDLNLLQIE
                     KESTTNKKVPMSVYFEKDDLDLLKAIAFEKNTTVNKVLMSIIKEPLKTTKVNLPHNFDI
                     NEKAKEYEVNSKKRKVEKKVETRGRKKKIK"
     CDS             complement(4997..5575)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MIYGYCRVSSRSQLDNNSLEIQEREISERYENAIIYKEQISGIKS
                     HRPVFNEILDKLKKGDTLVTTKLDRLCRSTKEGLEIIKNLQEREINIHILNMGLIENSP
                     MGDLIITCLLAFSQFERSMIVERTSSGKELAKINDDYREGRPKKFTKKQISHALKLLET
                     HSYKEVGLMTGISKSTLIRAKREHKSIGI"
     CDS             complement(5776..5976)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MNNGIVKWFNNEKGFGFISVEGGDDVFVHFSAIQTDGFKSLEEGQ
                     RVNFNIVKGARGPQAENVTIL"
     CDS             complement(6184..6453)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MKCIISFKELYGKELEKYEVEGKHSGDVLQAMENKLCSEIEPYNT
                     YSLKNCKNIDKKASKKTLHFKDNEGNMLSYVMEILDARYLKKNI"
     CDS             complement(6612..9344)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MENKDVFKDAVDEIRSLNCLISIMQNYNINLEKDNTGYYTNCVFH
                     NDKTPSLRLSDKGNRAIYHCFGCGEKGDILNFICRMENLDNTTALRRAYDILGRELKYN
                     TISDNKVENFKNFIKTNQSKIIKNKETYNLEEIYIYFDEDKKPLYCKTKYKNLFGKKHF
                     ITKSLIEMDIGYKYGEHEDFEQCKKVLYNLVEIKKVILKDDWIFFVEGEKDVETLRKIN
                     FPATTIYTKKWQNSYNEDLKNAKVAFIGDSGKSGQEFKNFMIEKLKKCCKGLKIIDLPG
                     VEKIGNGKNKDVTDWLESGKTSNELLQIVKKSLNILDKNTLQQDENGIYEIIDKIENEE
                     VKESRRNLTNFKIIDATLYRNEDNNDQIIKLNLKSNHRQSIIEADARECFSDVKIFRRY
                     LGIDYIFYGEIQDLTKLHQWIINYFIKEYISIFTRTGIRKINDEYVLVTNKGILKANGD
                     FDTTGKATNMIHNIDFTNLNILNKDEAERLSKHLFNCNSKENIYNTLGLGAANILNTFA
                     RESSIDNLPILQNLGESKSGKSKVLKILRLLFNDTNPAINLSVSTDFELLKSFDETYLP
                     VFLDDVKISKVSDCKINSLSNHIHAITEEYENTKVTENLTLQKFAYNASLIISGDEEIQ
                     ETAVKSRSNIVWYTISNFTREGKESVEFLCNSEEGKKLIRRFSKSLYFRVLNYYIYGAF
                     DNEYLVTRFKYGFDEKLSLSNSREINTATYTMMGLELIYNTFESLGVEINKIIDLEEVS
                     DIIINNLKSNILEENQNGFKSDYEKILKDINNLIYIPDRKIRLEENVHYKILPNNIHIA
                     FDFKTIYDKLNNYYKQYKNDSEKLLNYNTFTKMISKSTYIADLDPRKHYKSVKIKVLVE
                     NKNGFPDYIIKNKKMFILKIDEVKKLEMDNIFPMDNNEG"
     CDS             complement(9728..9973)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="VQRAIEEAGIPTVIIAALPPVVRQTGTPRAVAPLVPMGANAGEPN
                     NREMQYNIVKDTLVQLHEIQTPGKIVPLAYEYVAKV"
     CDS             complement(10001..10495)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_13"
                     /sec_met_domain="GRDB (E-value: 4.8e-20, bitscore: 62.3,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTICKLSKLKGGKKMSLTVVKGMQSEIFVPITPPSVWAPVTKPLK
                     EMKIALATAAGVHHKDDKRFNLAGDFSFREVRDNMLSKDLMVSHGGYDNGDVNKDINCM
                     FPIDRLHELAAEGFIGGVAPVHIGFMGGGGNQQKFKEETGPEIARILKEEGVDGVLLTA
                     G"
     CDS             complement(10562..10840)
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MKNDKLKYGDKILYMEGVIVEVHDGCVSVDLKGRLGYLKVPMRMF
                     ISDYEIKIGQEVGFNMSFVEQLGDEINEKYISNLMTRNKKIDEMSNK"
     CDS             complement(10857..12695)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_15"
                     /sec_met_domain="Proline_reductase (E-value: 8.9e-197,
                     bitscore: 643.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITAETAKQHANDPAVFCCRAEEGLVIGPANLEDPAIFDELVDS
                     GLLNLDGCLTIGQILGAKLTKTCDSLTPITADVIDAIVETKEEEAVVEEVKEEVKPAPV
                     ATQVQGGRLKIHIGEGKDINIEIPVGGFASQGGAQVVPVGENASVAPAAKEVEKEAKVV
                     RSLTRNHYKITEVKRGPETKIEGTVLYIREGIEEEAVASQKLVNSLKIDIITPDRYNTY
                     SETIMDVQPIATKDGEDELGLGTTRVIDGVVMMVTGTDANGVQIGEFGSSEGILEENIM
                     WGRPGCPEKGEIFIKTEVIIKEGTNMERPGPLAAHAATDFITQEVREALKKLDDELIVD
                     SETFDQVRRPGKKKVVIVKEIMGQGAMHDNLILPMEPVGILGAKPNVDLGNVPVMVSPL
                     EVLDGCIHALTCIGPASKEMSRHYWREPLVLEALHDEEVDLCGVIFVGSPQINSEKFYV
                     SRRVGMMAEALDVDGAFVTTEGFGNNHIDFASHIEQIGMRGIPVVGMSFCAVQGALVVG
                     NKYMTNMVDNNKSEAGIENEVLGCNTLCHEDAIRALSSLKTEMGGEAIAKPEKKWNPNV
                     KDTNIELISNVTGKPVELVENETSLPMSDKRKAKYS"
     CDS             complement(12848..14311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RnfC_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_16"
                     /sec_met_domain="SLBB (E-value: 6.1e-06, bitscore: 16.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.3e-38, bitscore:
                     121.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.7e-16, bitscore: 50.5,
                     seeds: 53, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLQKILLRQHVGAPCEAVVKVGDKVKKGSLIAKPTGLGANIFSS
                     VYGNVSEITEDAIIIERDEEQPEEFIKLEGDDKLQLIKDAGVVGMGGAGFPTAIKLGTK
                     VKYILVNAAECEPLLHHNVDQMVDNTDMTVRGLKYVMEICQAEKGIFALKAKNQKAVDA
                     LVEGTKGDDSLDIHLLPDIYPMGEERAVVREVLGILLQPTDLPSVADAVVINVETLQRV
                     AEAIELRKPCFSKNVTVVGKLNGGTEPHVFMDVPVGTSVKELIERAGGIDGEYGEVIMG
                     GPFTGKACELDAPITKTTGGIIVTQPFEDLKGEKMGLLICACGGNEERMQDLAKKMNAE
                     VVCVQKCKQAADVKGNLKCENPGNCPGQALKVMNIKKAGAKHILIGNCTDCSNTVMGSA
                     PKMNIEVHHQTDTVLKTAGKDVIRYMTASKTVPQLGEEVVEEVLVKAQSVEEPKVETAE
                     TNFASFTDDGGLVINLKEGKDIRVEFVID"
     CDS             14985..15749
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_17"
                     /sec_met_domain="Proline_reductase (E-value: 1.5e-67,
                     bitscore: 218.4, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEINLRRLVIKSYHINEVEFGAENNVFLDGKLTVCKDVLKDLI
                     ESEPLIKDINIQIIKPGDHDRFTNTMMDIIPISTKVLGKIGEGITHTLTGVYVMLTGVD
                     VNGIQTAEFGSSEGNLKEQLFLNRPGTPGDNDYIISFDVTLADGQGQVRPGPTAAHRAC
                     DKFCNEFRAKLKKLNGHKFTERHEFYDKVRPGKKKVVIIKQVAGQGAMYDTQLFSHEPS
                     AMEGGRSIIDMGNVPMIVTPNEYRDGALRCMC"
     CDS             15762..16232
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_18"
                     /sec_met_domain="Proline_reductase (E-value: 8.8e-33,
                     bitscore: 104.1, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIGPSTKETTLHHFRDPLLDVVSNDEDIDLLGIIVVGTPQDNED
                     KLFVGTKAASWAEAMRADGAILSSDGWGNSHVDFANTVEQVATRGIPIVGLTFVGTVAQ
                     FVVVNEYMDTIVDMNKNPEGIESEIVGENEVTELEAKKALALLKLKMRKYGK"
     CDS             complement(17173..17358)
                     /locus_tag="ctg2_19"
                     /transl_table=11
                     /translation="AMAMEKACKSENVPGRLIPVPRQISAGCGLSWLCNKEDKEKVESL
                     INNNNLDFQNIHEIMM"
ORIGIN
        1 tttatcgcat cttcttcgtt taaatactcg tggaatatca tttcaagtat tgttgcagta
       61 aacttatcta tcctaaatgc cctcgtaaga ggatttttct tcatcttatc gatatatttc
      121 ttctttccaa caataattcc agcctgaggg cctcctagga gcttgtctcc tgagaaagaa
      181 actatatcta cacctgcttt tatggaatct tgtacagtag gctcatattc taaaccatac
      241 ttactaagat caactaaaac tccacttcct atatcttcta taactggtat gtctttttct
      301 gttcctaatt tacaaagttc atatatagac acactttcag taaatcctag tattttaaaa
      361 ttacttgtat gaacttttaa gaaggctcct gtattttcag taatagcatc ttcataatct
      421 tccaaatgag ttttatttgt tgttcctatt tcaactaaat ctgccttgga gcttttcatt
      481 acatctggaa ttctaaactt acctccaact tcaacaagtt cacctctaga aactataact
      541 tccttgtttt ctgccataga tgataaaaca agcattacag ccgctgcatt attatttact
      601 gccatggcac cttctgcacc agttatttta caaattaatt tttcaaaatg agagtaacgt
      661 tctcctcttt tgccttcttc caagttatac tccaagttag aatagcttgt cacaacttca
      721 ctaagataat cagcatgttt ttttgaaatt atggctctac ctaagtttgt atgaagtata
      781 gttcctgtac catttataac ctttcttaag ttatatgagt aaactttttg aacattcaaa
      841 gcaatatttt ctactaaatc atttattttt tcttcaatca aagacatatc atcattttct
      901 cttatgaggt ttctaagttt atctatttct tctctaatag catctacaac cacatctcta
      961 tgatattttt ctattagatt tataatttca gttttttcta atagtacatc aactttaggt
     1021 atatttctaa ataacatatt tttattcata tattgttcaa gacctttccc ctttttttac
     1081 tcaaaatccc ttatagtaat ataagtttta actactaaag atttttgact aaattaatac
     1141 ttttttcttg tttttctatt acttttccta ttatagctac tttagtgtcc atatttttat
     1201 tttcaaagtc tttaataatg ttttcaactt cactttctgg taaagtgatt aacagtcctc
     1261 cagaagtttg tggatcatat aatacatcta taaaactttc ttctatattt tcactattta
     1321 catcatttga gatataatcc ttattgttgt atgttcctgc aggtactaga cccattttag
     1381 caaactctat cgcaccatca atgtatggca cttttttcac atctatttca aacgttactt
     1441 tagagctaga tgccatttcc attgcatgtc cagcaagacc aaatcctgtt atatctgtac
     1501 aagcacttat gttgtaattt tctataactt ctttggcttt tttattaaga gaagtcatta
     1561 ctgttacaac ttcatctatt tgagattgtt cagccatatc tgcctttatt gccgtattta
     1621 taagtccact tcctatttgt tttgtaagaa ttattacgtc tcctggcttt gatccataat
     1681 ttttaaatat tttctctgga tttacaaatc ctgttacgct aagtccatac ttaggttcat
     1741 catcttgaat agaatgtcct ccagcaagta ttgcaccaga ttccatcacc ttagaggctc
     1801 ctccttccaa aattcttcca agtattttag ggtctaaaca attaggaaat ccaactatat
     1861 ttaaagcagt tttaggctct cctcccattg cataaacatc acttaaagag tttgccgccg
     1921 ctatttgtcc aaataaatat ggatcatcaa caattggagt aaaaaagtct aacgtttgaa
     1981 tcaaagcaag atcatcactt actttataaa ttgctgcatc atcgctagtt tctataccta
     2041 ctaataaatt ttcatcatga aactttggta aattacccaa aacttgggca agggtcccag
     2101 gacctatttt agccgctcag ccagcagttt ttgtcatatg tgttaatttt atatcttcag
     2161 tcatcatatt tcttccctct tctataaatt attaaatttg tatacaaact tactactttc
     2221 tataatgtta cttatagaaa tattttataa caaaacttaa tctttgcaca ccttatttat
     2281 agttttagta atcttaatac ttaattatta tatataatat ctttatctct tagttcaaac
     2341 aagctattct catatttagc cttcggggat gtctatcccg atgacataga tagaccctat
     2401 agcacgaaat caaaatttct gacttaatac tatagggtct agtcatattt tagccccttt
     2461 ttcagttcta gagccctcag catatccctt gttagactac ctttcggatg taattttgtt
     2521 attattgtat ccatacccaa caactgaaag cattgtacct ctcagtaatt acacgaccta
     2581 atttgcatca ctacaaatta tatggttgcc acctgacctt tttattggat gtcaactcct
     2641 atcacttagg atctttggca caacaaggga aacagcctcc tctaagttgt tgattttttg
     2701 caacggctca actaacctat ctactttttt aagaggttgc aggcattccc tctttttcca
     2761 taaattttca ttttttaagc attaaaaaaa gcctgttctt caattgttga aaaacaggct
     2821 ctaagttcat tagttgttaa ttaaatgtat ataaaaattt tatattatgt acactttttt
     2881 aaaacttcca tctttacaga ttcattaaaa ttttatataa tctaataaga ttatattttt
     2941 gtaaacagaa gttttaaatt tactaactct ttaatactgc tccaacagtt ttaaggttta
     3001 atatatataa gatgctccaa cattttatat atactgtgga tttaagactt ttttttattt
     3061 aatttttcta aacttattct actacgtttt ttttcataat acaagaaaaa aatccttttt
     3121 aatttcaaat aatatatttt tctcaagaat ttccttaaaa tttcaacatt tattcagtat
     3181 ataaatattt tttttacaaa tcagtgttta acattattcc gattatattc gctttttgtt
     3241 gaaaaagttt tagttacata atataatttt atatgaagaa taaattgcgt atacttttta
     3301 atagctttga tagtcaaatc gaccaattgt tttacaaatt gtcaaaccaa tggttttaca
     3361 atttatagta ccaattgtta cacaatttgt aatgcaaatt ataaaaccat tggtttgaca
     3421 attattaaaa taattattta tcatatagct taaccaattg ttcaccaata gtaaaacaaa
     3481 ttgctataca attggttatt ttcacaaaag gagatgagaa agtgaagata gtaagttttt
     3541 tcaatgtaaa gggtggagta ggaaaaacca ctctaacaat tttaagtgct atagctctta
     3601 gtaaagaggg gtctcgcgtt ttaattatag acgcagatac acaggctaac ttaactcagt
     3661 ttctatacaa agtttcacat agtgacaaaa ctatgtttga cggactagct gataatttaa
     3721 gtgcagaaga attaataata aaatcacctt gcgaaagata caaaaacata gatataatcc
     3781 cttcagattt atcattgtct gtacttagtg aatatttaac tacaaaaaca aatcgtgaaa
     3841 aatcagtatg gagatggttc aagtccaatg tgaatgcttt aggtgactat gactacatat
     3901 ttgtagactt atcaccatca tatgatttga ttgcaagaaa ttttatgctt tgttctgatt
     3961 caatcataac tcctattgct tatcaagata tagcaagtat tagaggatgt gagttatttt
     4021 acttaaaata caatcaagat cttgaagata tggaaatgga gaatatggca aaaagagctg
     4081 tagttataaa ctcttatact tcaagaaaac tatctaccgg cgatatattc ttggaaaaac
     4141 taaatgaatt tgagcacata aaaaaagact taattaatgc aaaaatatcc gatacaacag
     4201 taataaaaaa tgcaattctt tctaaattag acatcgatga ttattgcaga aaaataaaaa
     4261 aatctcataa agttagagaa gaatttaaag aagttattaa tgaattaaaa gaaagggatg
     4321 tattatagtg ggactagata aatttttaaa agatgacaaa aaagaagaat taattttaac
     4381 aaaaaaagac tacaaatcta aggtaaatca tatagtaaaa aacacttttg aaaaagatga
     4441 tttaaattta ttacaaatag agaaagaaag cacaactaat aaaaaagttc ctatgagtgt
     4501 ttactttgag aaggacgatt tagatttatt aaaggccata gcttttgaaa aaaacactac
     4561 agtaaataaa gttcttatga gtataataaa agaaccttta aaaactacaa aagtaaattt
     4621 accacataat tttgatataa atgaaaaagc aaaagaatac gaagtgaata gtaagaaaag
     4681 aaaagttgaa aaaaaagttg aaacaagagg cagaaaaaag aaaataaagt aggactttat
     4741 gtcctacttt ttatttttat tattaaatct atttttttca atttattaag taattttaat
     4801 tcatacttag atacgtctat cttatgtttt tttattaatt taactatatt tatttaccat
     4861 ttactctata aaaaatacat agccttaact ttccctcaaa ttttattttg atgttattgt
     4921 aatttaaggt ttaaatattt ttaccaattg tttaaccaat tgtaatacta attgtttaac
     4981 aattggttat ttatttctat attccaatac ttttatgctc tctttttgct ctaattaaag
     5041 tactctttga tatgccagtc ataagtccta cttctttata tgaatgggtc tctagcaatt
     5101 ttaaagcatg tgaaatttgt tttttagtaa actttttagg tcttccctct ctgtaatcat
     5161 catttatttt agccaattcc ttaccagatg aagttctctc aacaatcatg gatctttcaa
     5221 actgagaaaa tgcaagaaga catgtaatta ttaagtcacc catgggggaa ttttctataa
     5281 gtcccatatt taatatatgt atattaattt ctctttcttg taaattctta ataatctcta
     5341 atccttcttt tgtacttcta cataatctat ctaactttgt agtaactaaa gtatctcctt
     5401 tttttagttt atctaatatt tcattaaaca caggtctatg agatttaatt ccactaattt
     5461 gttctttata aataattgca ttttcatatc tctctgaaat ttctctttct tgtatctcta
     5521 aagagttatt atctaactgg cttcttgaac taaccctaca atatccgtat atcattactt
     5581 cccctttcta ctttactgat caaaatacag ccgacttttg acactatatt ttgatactct
     5641 tttatacatt aatataactt atataaaata aaggtgtcaa tatatataag ttatgacacc
     5701 ttttatatga ttatttactt atttaataca acaaaaaaag acacaaattg tgtctttttc
     5761 cacgatacat atatattata atatagttac gttttctgct tgaggacctc tagcaccttt
     5821 aactatatta aagtttactc tttgaccttc ttctaatgat ttaaacccat cagtttgtat
     5881 agctgaaaaa tgtacaaata catcatctcc accttctact gatataaaac caaatccttt
     5941 ttcattgtta aaccatttta ctattccatt attcattaaa aaatactcct ataaacctat
     6001 ttctaggttt tttaatttat ttgtgtatta ctacggatat tattatagca catatgagta
     6061 ataatagata gtatttttta tatttttatt tattttttag gttataaact taaatataag
     6121 tatttagaaa taaaaaagac tgctctttaa agcaatcttc tatatttcat ttaatttcta
     6181 aatctatata ttctttttca aatatcgtgc atctaagatt tccataacat aacttaacat
     6241 attaccttca ttgtccttaa aatgaagtgt tttcttgcta gctttcttgt caatattttt
     6301 gcagtttttt aatgaataag tattatatgg ttcaatttca ctacaaagtt tgttttccat
     6361 tgcttgtaat acgtcaccag agtgttttcc ttctacttca tacttttcta gttccttgcc
     6421 ataaagttct ttaaaactaa ttatacattt cattttctac tcctccttat tgaacaactt
     6481 atatataaat tcaataaata agtaaaaaaa cctttatttc aacaaatttt attatataaa
     6541 tatttaattt tcatccacat tacttatctt taaattataa cttttttgct tttatttaat
     6601 atttcctaca attatccttc attattatcc attggaaata tattgtccat ttcaagtttt
     6661 ttaacctcat ctatttttaa gataaacatc tttttatttt ttataatata atctggaaat
     6721 ccatttttat tttctactaa aacttttatt ttcactgatt tataatgttt tctcggatct
     6781 aagtctgcaa tgtatgttga tttgcttatc attttagtga aagtattata atttaaaagt
     6841 ttttcactat catttttata ttgtttgtag tagttgttta atttatcata aatcgtctta
     6901 aaatcaaaag ctatatgtat attattgggt aaaatcttat aatgaacatt ttcttctaat
     6961 cttatttttc tatctggtat gtaaattaaa ttattaatgt ctttaagtat tttttcataa
     7021 tcactcttaa aaccattttg gttttcttcc aatatatttg attttaagtt gttaattatt
     7081 atgtcagata cttcttccaa gtcgattatc ttattaatct caacgcccaa agattcaaat
     7141 gtattatata taagctctag acccatcatt gtatatgtag ctgtatttat ttcccttgaa
     7201 ttacttaaag atagtttttc atcaaaacca tatttaaacc ttgttactaa atactcatta
     7261 tcaaaggctc cataaatata ataatttaaa actctaaagt ataaactctt tgaaaatctt
     7321 cttatcaatt ttttaccctc ttcactatta cataaaaact ccacagattc ttttccttct
     7381 ctagtaaaat tgcttatggt ataccatact atatttgatc tgctttttac agcagtttct
     7441 tgaatttctt cgtctcctga aattattaaa gatgcattat aagcaaattt ctgcaaagtt
     7501 aaattttcag tgactttggt attttcatat tcttctgtaa tggcatgaat atgattcgat
     7561 agggaattta ttttacaatc gcttaccttt gaaattttca cgtcatctaa aaatacaggt
     7621 aagtaagttt catcaaagga tttaagcagt tcaaaatctg ttgatacaga taaatttatt
     7681 gctggatttg tgtcgttaaa taataacctt aaaattttta gtactttact tttaccactt
     7741 ttactttctc ccaaattttg aagtattggc aaattgtcta tggaagactc tctcgcaaaa
     7801 gtattcaata tatttgcagc tccaagaccc agagtgttat atatattttc ctttgaatta
     7861 caattaaata aatgtttact taatctttcc gcttcatctt tatttaaaat attaaggtta
     7921 gtaaaatcaa tattatgaat catatttgtt gctttccctg tagtatcaaa gtctccattg
     7981 gcttttagta tacctttgtt tgtaacaaga acatattcat catttatttt tcttattcct
     8041 gttcttgtaa atatagatat atattcttta atgaagtaat ttataatcca ttgatgaagt
     8101 tttgttaggt cttgtatttc cccataaaaa atataatcaa ttcctaggta tcttctaaaa
     8161 attttcacat cagaaaaaca ttctcttgca tcggcttcaa taattgactg tctatgattt
     8221 gatttaaggt taagctttat aatttgatca ttattgtctt catttctata taatgtagca
     8281 tctattattt taaagtttgt tagattacgc ctactttctt tcacttcttc attttctatt
     8341 ttatctataa tttcatatat tccattttca tcttgttgta gagtattttt atctaatata
     8401 tttaaagatt tttttactat ttgtaaaagt tcattagatg ttttaccaga ttctaaccaa
     8461 tctgtaacgt ctttgttttt tccattgcct attttttcaa ctcctggtaa atcaattatt
     8521 tttagtccct tacaacactt ttttaatttt tctatcataa agtttttaaa ctcttgcccc
     8581 gattttccgc tgtctcctat gaaagccact ttggcatttt ttaaatcttc attataagaa
     8641 ttttgccatt tttttgtata aatagttgta gctggaaaat ttatttttct taaagtttcc
     8701 acgtcttttt caccttcaac aaagaatatc caatcatctt ttaatattac ctttttaatt
     8761 tctactaaat tataaaggac ttttttgcat tgctcaaaat cttcatgctc tccatattta
     8821 taacctatgt ccatttctat taaagacttt gttataaaat gctttttacc aaataagttt
     8881 ttatatttgg ttttacaata taatggcttt ttatcttcat caaaataaat ataaatttct
     8941 tctaaattat acgtttcttt gttttttatt atttttgact ggtttgtttt tataaaattt
     9001 ttaaagtttt ctactttatt gtcgctgata gtgttgtact tcaactccct acctaagatg
     9061 tcataagctc ttcttaaggc tgttgtatta tctaggtttt ccatcctaca aataaagttt
     9121 aaaatatctc ctttttcccc acatccaaaa caatggtaaa tagctctatt tcctttgtca
     9181 ctgagtctta agcttggtgt tttatcattg tgaaacacac aatttgtata atatccagta
     9241 ttatcttttt ctaaatttat attgtaattt tgcataattg atattaaaca atttaatgat
     9301 cttatttcat ctactgcgtc tttaaaaaca tctttgtttt ccattaagac caccacctaa
     9361 ctgtgtatta ctttgcattt ttcgaggaat ttgttgtacc gtatttgtat atttcaatta
     9421 aacaacctcc tttttaggag ggcttacagt ctcttattag caaaacttaa gagactttta
     9481 tgcccaaatg tttatgttat aatattttat agtgtaaaat attataacat aaacatttac
     9541 aaaatatatt gtaaattaaa cgcttccgaa tcaattcgca atatttaatt tacatattaa
     9601 aattttcaag ttctaatata aatcttattc aaaataaaag attgtaatta cgatgttaaa
     9661 ttatattttt taataaaaaa actgatagga ataaatccta tcagtctttt taacatatat
     9721 gctaatatta aactttagct acatactcgt aagctagtgg aactatctta cctggagttt
     9781 gtatttcgtg taattgaact aaagtatctt taactatgtt gtattgcatt tctctgttgt
     9841 ttggttctcc agcgttagca cccattggaa caagtggagc aactgctctt ggagttcctg
     9901 tttgtctaac tactggtgga agagctgcta ttataactgt tggtatacca gcttcttcaa
     9961 tcgctctctg cactaaaact gcagagcggt ggcaagttcc tcagccagct gtaagaagaa
    10021 caccatcaac gccttcttct tttaatattc tagctatttc tggacctgtt tcttctttga
    10081 atttttgttg gtttccacca ccacccatga atcctatgtg tactggtgca actccaccta
    10141 taaatccttc agctgcaagt tcgtgtaatc tatctattgg gaacatacag tttatatctt
    10201 tattaacgtc tccattatcg tatcctccgt gagataccat aagatctttt gataacatat
    10261 tatctctaac ttctctgaaa gagaaatcac cagctaaatt gaaacgcttg tcatctttgt
    10321 gatgaacacc agctgcagta gcaagagcta ttttcatctc ttttaaaggc ttagttacag
    10381 gagcccatac tgatggtggt gttattggaa cgaatatttc agattgcatt cctttaacta
    10441 ctgttaaact catctttttt ccccctttta atttactcaa tttacaaatc gtcatgtaaa
    10501 tgagcctgag ttaatttact actcaaatct atatttttaa atatacaagt tttgagtaaa
    10561 tctatttatt agacatttcg tcgatttttt tatttctagt cataagattt gaaatatatt
    10621 tttcattaat ctcatcacct aattgttcaa caaagctcat attaaagcct acttcttgac
    10681 caattttgat ttcgtaatcg gaaataaaca ttctcattgg aacttttaag tatcctagac
    10741 gtccctttag atcaacgctt acgcatccat cgtggacttc tacaataaca ccttccatat
    10801 aaagaatttt atcaccgtat tttagtttat catttttcat tatgcgtcag ttcttcctag
    10861 ctatattttg ccttacgctt gtcactcatt ggaagagaag tttcgttttc aactaactca
    10921 actggctttc cagtaacatt agatattaat tctatgttag tgtcttttac gtttggattc
    10981 catttctttt ctggtttagc tattgcttct ccacccattt cagtttttaa tgaagaaaga
    11041 gctcttatag catcttcatg gcataaagtg ttgcatccta atacttcgtt ttctatacca
    11101 gcttctgatt tgttgttatc taccatgtta gtcatatact tgttaccaac aactagagca
    11161 ccttgaacag cacagaatga cataccaact actggtattc ctctcatacc tatttgctct
    11221 atgtgagaag cgaagtctat atggttgttt ccgaatcctt cagtagtaac gaaagcacca
    11281 tcaacatcta aagcttcagc catcatacca actcttcttg atacgtagaa tttctcagag
    11341 tttatttgag gagatccaac aaatataaca ccacataaat ctacttcttc atcatgtaaa
    11401 gcttcaagta ctaatggctc tctccagtaa tgtctagaca tttcttttga agcaggtcct
    11461 atacaagtta atgcatgtat acaaccatct aatacttcaa gtggagatac cataactggc
    11521 acgtttccta agtcaacgtt tggcttagct cctaatattc caactggttc cattggtaat
    11581 attaagttat catgcattgc accttgaccc attatttctt ttactataac aacttttttc
    11641 tttcctggtc ttcttacttg atcgaaagtt tcactatcta ctattaattc atcatcaagt
    11701 tttttaagag cttctcttac ttcttgagtt atgaaatcag tagcagcatg agcagcaaga
    11761 ggtcctggtc tttccatgtt agttccttct ttgattataa cttctgtttt gatgaatatt
    11821 tcaccttttt caggacaacc tggtcttccc cacatgatat tttcttctaa gataccttca
    11881 gatgaaccga attctcctat ttgaacacca tttgcatcag taccagttac catcattaca
    11941 acaccatcta ttactctagt agttccaaga cctaattcat cttcaccatc tttagtagct
    12001 attggttgaa catccattat agtctcagag taagtgttgt atctatctgg agttattata
    12061 tctattttta agctatttac taacttttgg ctagctacag cttcttcttc tataccttct
    12121 ctgatgtata aaacagtacc ttctatttta gtttcaggcc ctcttttaac ttcagttatt
    12181 ttgtagtggt ttctagttaa gcttctaact actttagctt ctttttctac ttctttagct
    12241 gcaggtgcaa cagaagcatt ttcaccaact ggaactactt gagctccacc ttgagaagcg
    12301 aatccaccaa ctggtatttc tatattaatg tcttttcctt cacctatgtg gatttttaat
    12361 cttccacctt gtacttgagt agcaactggt gctggtttta cttcttcttt aacttcttct
    12421 actacagctt cttcttcttt agtttcaact atagcatcta taacatcagc agttattgga
    12481 gttaaagaat cacaagtttt agttaatttt gcacctaata tttggcctat agttaagcaa
    12541 ccatctaagt ttaaaagtcc agaatctact aattcatcga atatagcagg atcttctaag
    12601 ttagcaggtc ctataactaa tccttcttct gctctacagc aaaataccgc agggtcattt
    12661 gcatgttgct tagcagtttc agcagttatt gacataagtt ttccccctta tataataaat
    12721 cattttattt ttataatttg aacatgaaat actaatttat atcaaagaaa tttctttctt
    12781 tgttaacatt taattattta tagaagtatt tttatacttt ctataagttt tcccttattt
    12841 gagaaaatta atctataaca aactctacgc ggatgtcttt tccttcttta aggtttataa
    12901 caagtccacc atcatcagta aatgatgcaa agttagtttc agctgtttct acttttggct
    12961 cttctactga ttgagcttta acaagtactt cttctactac ttcctctcca agttgaggaa
    13021 ctgttttaga agcagtcata tatcttatta catcttttcc tgctgttttt aatacagtat
    13081 ctgtttggtg atgaacttct atattcatct ttggagcaga tcccataact gtatttgaac
    13141 agtctgtaca gtttcctata agtatatgtt tagctccagc ttttttgatg ttcataactt
    13201 ttaatgcttg tcctggacaa tttcctgggt tttcacattt taagttacct ttaacatctg
    13261 ctgcttgctt acatttttga acacaaacaa cttcagcatt cattttttta gctaagtctt
    13321 gcattctttc ttcgttacca ccacaagcac aaattaaaag tcccattttt tcacctttta
    13381 aatcttcaaa aggttgagtt actattattc cacctgtagt tttagttatt ggagcatcta
    13441 attcacaagc tttaccagtg aatggtccac ccatgattac ttctccatac tctccatcta
    13501 ttccgccagc tctctctatt aattctttaa cagaagtacc aactggaaca tccatgaata
    13561 cgtgaggttc agtaccacca tttaatttac caacaactgt aacgttttta gagaaacatg
    13621 gctttctaag ctctattgcc tcagcaactc tttgaagagt ttcaacgttt ataactacag
    13681 catctgctac tgatggtaaa tcagttggtt gaagtaatat tcctaaaact tctcttacaa
    13741 cagctctttc ctcacccatt gggtaaatat ctggaagtaa gtgtatatct aaagaatcat
    13801 cacccttagt accttcaact aaagcatcaa cagctttttg gtttttagcc ttaagtgcga
    13861 atattccttt ttctgcttgg caaatttcca taacatattt aagacctctt acagtcatat
    13921 ctgtattgtc taccatttgg tctacgttat ggtgaagtag tggttcacac tcagcagcgt
    13981 taacaaggat gtattttact tttgttccaa gttttatagc tgttgggaat cctgcaccac
    14041 ccattcctac tacaccagca tcttttataa gttgaagttt gtcatctcct tctaacttaa
    14101 taaactcttc tggttgttct tcatctcttt ctattattat ggcatcttca gttatttctg
    14161 aaacattacc atatacacta gagaatatgt tagcacctag tcctgtaggt ttagctatta
    14221 gagaaccttt ttttacttta tctccaactt taactaccgc ctcacaagga gccccaacat
    14281 gttgtctaag taatatcttt tgtaatccca ttaagttcac cccctaataa tataaagcat
    14341 atatttgaaa ataatttgct tttatcatta aaaaataaaa aaacattaaa tttccttatt
    14401 tttaatattt aatcatatag ttttttttat atgtgttaaa aaaatcacac tgaaaacctt
    14461 ttcacttttt caaaaaaaat attttactgg cgggagaatg tgggaatcga acccacctag
    14521 gatgctacta acaccccaca ctggttttga agaccaggag gcacaccagt tacctatcta
    14581 ctcccattta cgcttcctaa atcattataa catcatttat cgataaatat tataaaatat
    14641 tttcaaatat agacaaaatt tataagattt tttaaaccta taaatattat aacaataaaa
    14701 attcacaaat tcaagaactc aatactagac taaagtctgt ttttataata taaatttttt
    14761 tttccattga aaagtctaat gaataagcct ttttggtaaa ttttgtttgt tattattttg
    14821 tcagttttat aatgtttttt atacataaat aaataatatg acgaaatatg ataaataaaa
    14881 tggttgatag gtcaaaagtt tacacactat aattatattg gaattaacaa ttttataaat
    14941 atgctttatt aatagaattt ttcaatataa aaggaggaga aatcatgagt gaggaaatca
    15001 acctacgtcg ccttgtgatt aagtcatatc acataaacga agtagaattc ggggcagaaa
    15061 ataacgtttt tctagacgga aaacttacag tttgtaaaga tgtgttaaaa gatctaatag
    15121 agtcagagcc tttaataaaa gacataaaca ttcaaataat aaaaccaggg gaccatgata
    15181 gatttacaaa cactatgatg gacattattc caatttcaac taaagtttta ggtaagattg
    15241 gagaaggaat aactcatact ttaactggag tttatgtaat gcttactggt gtagacgtaa
    15301 atggaataca aactgctgaa tttggttctt cagaaggtaa tttaaaagaa caattattct
    15361 taaatagacc aggaactcct ggagacaatg actatataat ttcatttgat gtaactttag
    15421 ctgatggtca aggacaagtt agaccaggac ctactgctgc tcatagagct tgcgataaat
    15481 tctgtaatga atttagagct aagttaaaga aattaaatgg tcacaaattt actgagcgtc
    15541 atgagtttta tgacaaagta agaccaggta agaaaaaagt tgttattata aagcaagtag
    15601 caggacaagg tgctatgtac gatactcaac tattctctca tgaaccaagt gccatggaag
    15661 gtggaagaag tattatagat atgggtaatg tacctatgat tgtaacacca aatgaatata
    15721 gagacggcgc tcttcgctgt atgtgctaag gaggtaaaat tatgggaata ggaccatcta
    15781 ctaaagaaac tactctacat cactttagag atcctctact tgatgttgta agtaatgatg
    15841 aagatataga tttattagga attatagttg ttggaactcc acaagataac gaagataaat
    15901 tatttgtggg aacaaaggct gcgtcttggg ctgaggccat gagagcagat ggagcaatac
    15961 tttcatctga tggttgggga aactctcacg tagactttgc caacactgtt gaacaagttg
    16021 caactagagg aattcctatt gtaggactta cttttgttgg aactgttgct caatttgttg
    16081 ttgtaaatga gtatatggat acaatcgttg acatgaataa aaaccctgag ggaattgaaa
    16141 gtgaaatagt tggggaaaat gaagtaactg aattagaggc taaaaaggct ctcgctttac
    16201 ttaaactaaa aatgagaaaa tacggaaaat aaaacttata aaaaagtgct gtaaattaat
    16261 tttgcagcac ttttttatat ttctgaaata aatacctctt atcttactaa agaatatata
    16321 aactatgccc aagttgtttt atttaaactt ttttattgta aaatctattc atcttatata
    16381 taataccttt tcagtaatgg gcatagtttc cctacaaaaa gtgtagagaa ctaatcttta
    16441 ataggtatac ccccccaggc gcgttaccac cgcgcaagga ttaaagaccc agtacaaaag
    16501 taagtatcct gcctttgtaa tttaatacta tttgccattc cccccggcaa cagacttatt
    16561 ggataccccc gcaaaggaat ttccacccct agctcttttt tgttgtagtg cctagttact
    16621 actttcagcc cttaaaatac tgtactggta tattcttata tgctgtggag actttcaccc
    16681 cagtgtttcg tcgacatccc ctgtaccctg tcgggccatt cggttagtta tccaggtcaa
    16741 acactcttcc ttataaaacc tatcttatat tcagtttttt agcattaaaa aagacctatc
    16801 caactgcttg gataggtcgt attgttcata atctttaaat tattaaattt atcctcttgt
    16861 ataaactagt aaaactagtt ataataatta gtataaattt aataataact atgttttgct
    16921 tatgaggtat ttgttctgaa atactttgta agagttcata gttaaaaggt tacttgtaac
    16981 actaactgtt ggcgcagttg gtactaattc cctctaaggt ttgcagacct tatggaaact
    17041 tgtaatcttt ttttatgcaa ttttttatat gagtctatta tatatccttt tttcttttgt
    17101 gacaatattt tattttatta actaaaaata gcaataattc atttcataaa gaaacaaatt
    17161 attgccactt gtctacatca ttatttcatg tatattttga aaatctagat tattattatt
    17221 tataagactt tctacttttt ctttgtcttc tttgttacaa agccatgaaa gaccacatcc
    17281 tgcagatatt tgtcttggta ctggtattaa tcttcctggt acattttcac ttttgcaggc
    17341 tttttccatc gccattgctc
//
