LOCUS       NZ_CP075979.1          24758 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP075979.1 Clostridium perfringens strain CPI 18-6 chromosome.
ACCESSION   NZ_CP075979
VERSION     NZ_CP075979.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:44:31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2860835
            Orig. end    :: 2885593
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24758
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2870835:2875593]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14758
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..24758
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24758
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="9"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(141..992)
                     /locus_tag="ctg1_2468"
                     /transl_table=11
                     /translation="MSKKSLIKNVYKKFQDVYNNYEILMSNSFLDDLGGNVSIIFFLFG
                     LIIGSFLNVCIFRIPAGESIAFPPSHCGTCKKQLKPIDLVPVFSYLFLGGKCRYCKSKI
                     SIRYPLIELLTGFLYFYVYKYYGISFLTVKYIVLITFLIVISFIDYDTQDVYAVTTYPA
                     VILGIIFALIEKFYFGENLLNYFMGLVISALVIFLISKLTGAMGSGDIEIHAIAGIFLG
                     WKLAIINIFLSFIIGGIIAVLAILFKQKKKGDYIAFGPAIGISTIILIFFGNIIIPIYF
                     GV"
     CDS             complement(1160..1369)
                     /locus_tag="ctg1_2469"
                     /transl_table=11
                     /translation="MLLAEDAISSSVTNIKITSSNGNVQISGISDDTGKSKLQDLLEDL
                     DKPQSGDSYNVDIENGRKVTVSIV"
     CDS             complement(1370..1582)
                     /locus_tag="ctg1_2470"
                     /transl_table=11
                     /translation="MLLLKASAICGKGNEGKRNKKGGFTLIELTVVLAIMAIILMVIAP
                     NFSYVKDSAKAKVDKQNCAAIERSV"
     CDS             complement(2248..3867)
                     /locus_tag="ctg1_2471"
                     /transl_table=11
                     /translation="MAKTLLFGEEARRSMQAGVDKLANTVKVTLGPKGRNVILDKKFGS
                     PLITNDGVTIAREIELEDAYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLK
                     NVTAGANPILIRNGIKTAVEKAVEEIQKISKPVNGKEDIARVAAISAADEKIGKLIADA
                     MEKVGNEGVITVEESKSMGTELDVVEGMQFDRGYVSAYMVTDTEKMEAVLDNPLVLITD
                     KKISNIQDLLPLLEQIVQAGKKLLIIADDIEGEAMTTLVVNKLRGTFTCVGVKAPGFGD
                     RRKEMLQDIATLTGGVVISDEVGGDLKEATLDMLGEAESVKVTKESTTIVNGRGNSEEI
                     KNRVNQIKLQLEATTSEFDKEKLQERLAKLAGGVAVVKVGAATETELKESKLRIEDALA
                     ATKAAVEEGIVPGGGTAYVNVINEVAKLTSDIQDEQVGINIIVRSLEEPMRQIAHNAGL
                     EGSVIIEKVKNSDAGVGFDALRGEYKDMIKAGIVDPTKVTRSALQNAASVASTFLTTEA
                     AVADIPEKEMPQGAGMGMDGMY"
     CDS             complement(3922..4206)
                     /locus_tag="ctg1_2472"
                     /transl_table=11
                     /translation="MSIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGP
                     GAIVDGKRTEMEVKIGDKVLYSKYAGTEVKFEGEEYTILRQDDILAIVE"
     CDS             4577..5227
                     /locus_tag="ctg1_2473"
                     /transl_table=11
                     /translation="MIKILKDILFSFYLLISSVVFSVILTLNISPVLYSLFIKLNIIPK
                     YNNLSSEEILNDYNNIIHYLNSPQEEVLKFKNFKISPIGEFHFLEVKEIFSSIYLIGLA
                     CLILGIILFIISKKFKLKISFKAFNIFFYEVLFIFLSLILSFYLNFSKVFTLFHKIFFN
                     NDYWIFDPKKDPIINVLPESYFLFLAIFILSLVMILSIISKIFYTLKKHKHLK"
     CDS             5376..5681
                     /locus_tag="ctg1_2474"
                     /transl_table=11
                     /translation="MNKETHICALCERKVPKITEHHLIPREKGGRFDETTWLCVPCHKQ
                     VHALYSNYELAVRLNSLPRLKDDEKIKRYLKFIKKQPGDANVTIKKSKAIRKKGRY"
     CDS             complement(5803..6741)
                     /locus_tag="ctg1_2475"
                     /transl_table=11
                     /translation="MDFKSVEYGENKVILKDAKNFNIKQVFECGQCFRWERTESGSYIG
                     VAFGKVIELAQEGHDVIIYNTNKEDFENIWVDYFDLERDYSKVKEALSWDETLKSAVEF
                     GYGIRILNQDPFELVISFIISARNSIPVISKTIKKISERWGEPIEYKGNTYYSFPTPES
                     LSKASIDDIRETGASFRSKYIWDTTKNIYNCELAKKGILDAPEEEIVEILEKYDLEKIT
                     NMDADGCHKGLQEFMGVGAKVADCIMLFSMKKSSAFPVDVWVKRAMMHFYGADDASLNK
                     IRIFARERFGEYSGFAQQYLFYYARENGIKI"
     CDS             complement(6751..7155)
                     /locus_tag="ctg1_2476"
                     /transl_table=11
                     /translation="MLVEKAREKWDKKHDLNCAECIMYAANEEYNLNLSKETLKVMSSF
                     GGGLAIGNVCGAATGAAGVLGLMFTEDRGHQSPQTRALTQEFMEKFYDKLGYYNCTDLK
                     AKYKKDDDRRCIVMIETAAEVLDEIVRRER"
     CDS             complement(7399..7899)
                     /locus_tag="ctg1_2477"
                     /transl_table=11
                     /translation="MNSKKIVNTIYYIVIFMLVIILVNNFMSKSDSIFKAVGFRTYSIL
                     SGSMEPEINTGDLAIVKSIDAEDVKVGDIITFKYEGKVVTHRVVEKNEEGFITKGDNNN
                     ANDTEIVRGEDLIGKVLFHMPFLGYVTVFLSKPIVISGLMVLIAISILWDTFKVDKKKT
                     IKA"
     CDS             complement(8041..9741)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     326.9; E-value: 1.5e-99)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_2478"
                     /transl_table=11
                     /translation="MLKRFIRYYKPYKKLFILDLLAAFLVSACDLFYPMITRNIINDVI
                     PNKQIKLLFVFAIVLTLIFLIKAGLNYFMQYWGHVVGVRMQADMRRDLFDKLQDMPNKY
                     FDNNKTGVIMSRIINDLLDISELAHHGPEDLFISLVMLVGSFIILCTINVPLTIITFAI
                     IPFLLFYTIHKRNKMKKAFKETRVKTGEVNATIENSISGVRVTKSFGNKSYEMEKFDKS
                     NGIFKKAREHAYKAMAEYFSGMFFLVDMLELIVLIAAGYFTYLGKINVGDFAAYLLYIK
                     MFLQPIRKLINFNEMFQNGMSGFERYEEIMNEENEKEIPNAKELKDVKGKITIKDVTFR
                     YDNKESILENFNLDIEAGKMVALVGPSGGGKTTICNLIPRFYDYESGQIFIDDVDISTV
                     TLKSLRENIGIVQQDVFLFTGTIKENIMYGNPNATDEEVIEAAKNACLHDFIMGLEDGY
                     DTFIGERGVKLSGGQKQRISIARVFLKNPAILILDEATSALDNVTEYEIQKALEELSKD
                     RTTLVVAHRLSTVKNSDEIVVLTDKGIEERGTHEELIKLGGVYSNLHNL"
     CDS             complement(10001..10849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2479"
                     /sec_met_domain="HCDH (E-value: 2.7e-36, bitscore: 121.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1e-70, bitscore: 234.7,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGIN
                     KGLTKLVSKGKITEEDKEAVLSKITGTTDLGLAADCDLVIEAAVENMEIKKQIFAELDK
                     ICKEETILASNTSSLSITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFD
                     KVKAMSEAIGKTPVEVAEAPGFVVNRILIPMINEAIGIYAEGIASVEDIDTSMKLGANH
                     PMGPLALGDLIGLDVCLAIMDVLFKETGDSKYRAHSLLRKYVRAGWLGRKTGRGFYNYN
                     A"
     CDS             complement(10963..11970)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 185.1;
                     E-value: 3.7e-57)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2480"
                     /sec_met_domain="ETF (E-value: 1.7e-55, bitscore: 185.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 2.9e-37, bitscore:
                     124.0, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKADFNGVWVFAEQREGQLQKVSLELLGEGRKIADKLGSKLTAL
                     LIGNKVQNLVEDLSRHGADEVLVVDAPELEHYTTDGYTKAICELANAKKPNIIFIGATF
                     IGRDLGPRVAARLETGLTADCTSLDVDVESGDLLATRPAFGGNLMATIVCPDHRPQMAT
                     VRPGVFEKLPLGENDATVENVEIKFNSNDIRTKIVEIIKEHKDIVDISEANVLVAGGRG
                     IGSEENFKMLKELAEVMNGSIAASRAAVEKGWVDKDYQVGQTGKTVRPNIYVACGISGA
                     IQHAAGMQDSDMIIAINKDANAPIMKIADYAIVGDVNKVVPEFIAQLKAMKEEA"
     CDS             complement(11992..12771)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 179.3;
                     E-value: 2.3e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2481"
                     /sec_met_domain="ETF (E-value: 1.1e-53, bitscore: 179.3,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVVCLKQVPDTTAVKIDPKTGTLIRDGVPSIINPEDKHALEAA
                     LQLKDNNGAEVTVLSMGPPQAKSALREALCMGADKAILITDRAFAGADTLATSKALAGA
                     LKKLEYDIIFAGRQAIDGDTAQVGPEIAEHLNIPQVTYVQGVKVEEDGLLVNRALEDGY
                     ELIKVKAPVLLTAIKELNEPRYMNVKNIFETSDDEILVWSADDIDVDKAELGLKGSPTK
                     VKRSMTKEAKGAGEIVKESPKDSVTYVLGKLKEKHYI"
     CDS             complement(12790..13929)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2482"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.6e-53, bitscore:
                     176.3, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.5e-28, bitscore:
                     94.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.4e-37, bitscore:
                     124.6, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFQLTREQELVKQMVREFAQNEVKPIAAEIDVTERFPMENVKKM
                     AKLGMMGIPFSKEYGGAGGDTLSYILTVEELSKVCATTGVIVSAHTSLCASLIDQFGTP
                     AQKEKYLTPLAKGEKLGAFGLTEPGAGTDAAGQQTTAVLEGDNYILNGSKIFITNGGVA
                     DTFIIFAMTDKSQGTRGISAFIVEKNFPGFSIGKLEEKMGIRASSTTELIMENCVVPKE
                     NLIGREGKGFGIAMKTLDGGRIGIAAQALGIAEGALEEAVAYMKERKQFGRSLSAFQGL
                     QWMVAEMDTKIEAARFLVYKAACLKEEGKPYSIDAARAKLFAADVAMEVTTKAVQLFGG
                     YGYTKEYPVERMMRDAKITEIYEGTSEVQKMVIAGSILR"
     CDS             complement(13976..14758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2483"
                     /sec_met_domain="EC1_2-faecali (E-value: 7.3e-88, bitscore:
                     291.5, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNNVIFEKEGNIGVLTINRPKALNALNSETLKDLDTAIDHIEK
                     QDDIYVVILTGAGDKAFVAGADIAEMKDLNEEEGKEFGLLGNKVFRRLENLDKPVIAAI
                     NGFALGGGCEISMACDIRIATTKAKFAQPEVGLGITPGFGGTQRLPRIVGPGKAKELIY
                     TGDMIKADEALRIGLVNKVVEPENLMEEAMALAKKISNNAPIAVKLCKDAINRGMQVDI
                     DSAVVIEAEDFGKCFATEDQTEGMSAFVERREKNFKNK"
     CDS             complement(15021..15659)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2484"
                     /sec_met_domain="CoA_binding (E-value: 2.3e-27, bitscore:
                     92.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKKGISMAVIKRLPKYHRYLQELMENDVDRISSKELSEKIGFT
                     ASQIRQDLNCFGDFGQQGYGYNVKELYNNIGSILGLTRDYNTVIIGAGNIGQAIANYNS
                     FNRLGFKLKGIFDANPRMFGIKIRDVEIQDVEKLKDFVKENDIEIGIICVPRTNAQKVC
                     NDLVEGGIKGIWNFAPIDLEVPKDIRVENVHLSESMMTLVYLLNHNDVK"
     CDS             complement(16125..18341)
                     /locus_tag="ctg1_2485"
                     /transl_table=11
                     /translation="MKDIKLYLDGLNCANCAGKIEDKVNKLTDVDEAVLNFSTKLLLIT
                     PKEGVSEKELEEKVEKIVLDLEPDVKVLKDKNKIKSSVNTCNDGCCGEGESHKHNNVES
                     HSHSHEHGHSHSHGGNSGIEKKELFRLGIALTLFIIGMIVNLDKMYEFIIFGVAYIIAG
                     GEVLLRAFKNILRGQVFDENFLMAIATIGAFAIGEFPEGVAVMLFYEVGEMFQDYAVNK
                     SRKSISDLMNIRPDFANLIDLNGEEKRVSPESVNVGSIIVVRAGEKVPLDGVVLSGEAT
                     LDVSALTGESLPKEVEAKDDVLAGSINKSGLLKIKVTKSFGESTVSKILDLVENAGNKK
                     SPTEKFITKFARYYTPVVVFSALALAIIPPLVISGESFSPWISRALIFLVVSCPCALVV
                     SIPLGYFAGIGLASKNGILIKGSNYLEALNNVESIVFDKTGTLTKGTFKVRKSESTSKL
                     TNEELLKLGAYAEYYSNHPIAKSIVSEFNEEINKDLISNYEEISGKGIKVDIDGETFLA
                     GNSKLMDMFNIKITPIHEIGTVVYLANEKSELGYIVISDEIKEDSKEAISGLKEIGVKQ
                     TIMLTGDNEKVGDSVAKELGLDKAYCSLLPQNKVEKLEQIFEDKSKGKKVAFVGDGIND
                     APVLARADIGIAMGGVGSDAAIEAADVVIMDDKPSKIIKAIKIAKKTNKIVWQNIIFAL
                     GVKIIILIFGALGMANMWEAVFGDVGVTLIAVINSSRILKNKNL"
     CDS             complement(18357..18716)
                     /locus_tag="ctg1_2486"
                     /transl_table=11
                     /translation="MDNNKIESCNCSYIHEDILSRVKEHLPKEEVLYELAEIFKVFGDS
                     TRIKILCALFEGEMCVCDMAELLGVSQSAVSHQLRVLKQARLVKFRREGKIVYYSLDDD
                     HVKHIFNEGLNHVLE"
     CDS             complement(19062..19682)
                     /locus_tag="ctg1_2487"
                     /transl_table=11
                     /translation="MESKVNEPIYKQIALDIAGRIYNNDIKVGQKIHGRSTLASSYNVS
                     PETVRKAVKLLEDMKVVSSSKGSGVTIISKDNAYNFINRFHSIESVTSLKHDIESLMEE
                     KKAIEKNIGEMIDKIVDYSNRLRYTNPLTPIEIELPKDCTLIGKSVSESKFWQNTQATI
                     VAIRRKGELIISPGPYLKFEKDDNLLVVGEEDILKKIEMFLNK"
     CDS             complement(19770..20348)
                     /locus_tag="ctg1_2488"
                     /transl_table=11
                     /translation="MLMNTHILIAQNILRDVDVDFKISDKNFIYGNVKPDMVSKYKLKK
                     HYLDESFDMIVNKIKKLASLSMYDFKKKFSVSRFSQELGVICHFICDFFCIPHSERWEF
                     KHSMNKHVKYEKELASFAKTYTPSQDDFKIWGNMSVKFFLEEAHKLYRKRESYENDMQY
                     AYFACRSIVKYISDCIARNTKAVYSEAIA"
     CDS             complement(20738..21304)
                     /locus_tag="ctg1_2489"
                     /transl_table=11
                     /translation="MSDRIVDFNELKNKARDKDIDKFESYIYDLYYSVAQGKMSMMELS
                     REITKYMNENNISQEKFLNIQTEMLKRYGFDMGDIEGQMKNLGIDMSNLGIQGGDYENL
                     RKTLSFQEKYKGKVKTSTVTTYFIKNEKNDIELILENNKVLITSPKNIDLQDSELNEFL
                     CSYKKTLSDDLLDIRICENVGQYNY"
     CDS             complement(21533..22603)
                     /locus_tag="ctg1_2490"
                     /transl_table=11
                     /translation="MLYSLILAGGKGTRLYPLSRSSNPKQFLSIHNNGKSFLSNTVDRI
                     RPIIHKDNIYVVTNQEYEDKIRDELKDIREENIFTEPANKETATCIGLSAAKLLKKDKD
                     AVMIVLPSDHYIEGDKSYLQTLEQAVEIADKKRAIVTIGIEPTRPETGYGYIEMGDRVN
                     GHIPTFKIARFTEKPNLEVAKDFLLKGTYLWNSGMFIFRADVILREIEKYIPKMYKCLM
                     EIYQHIGEDDEEEIIKEQYSLIDGISIDFGVMQKTRRSFVIKCDFSWDDIGTFSALSRF
                     LGPNGNNRTSDNVFLEECENCSVFGKEKLIIGFGIKDLVLVDAGDVILVMDKGRDQEIK
                     HLLNSISGKKEFKEYL"
     CDS             complement(22841..24220)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2491"
                     /sec_met_domain="Glyco_hydro_1 (E-value: 2e-119, bitscore:
                     396.4, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYTFPENFWWGAATSGPQSEGRFNKKHDNVFDHWFDINPELFHN
                     GIGPNIASNFYNSYKEDLAMLKEIGLNSFRTSIQWTRLIKDFETGEPDEDGVRFYNGVI
                     DECLANGIDIIMNLHHFDLPVELYDKYGGWESKHVVELFAKFAKTAFSLFGDRVKKWAT
                     FNEPIVIIEGQFLYKWHYPCIVDGKRGLQAAYNIALASARAIEEYRKLGQDGEIGIIVN
                     LTPAYPRSESKEDLRAAEIANAFFNELFLDPATKGEFPKNLVEVLEKDGVMWNSTKEEL
                     EVIKNNTVDFLGVNYYQPRRVKAREEEYVGETWAPEKYFDNYDMPGKRMNPHRGWEIYP
                     KAIYDIAKNVQDNYGNIKWFISENGMGVEGEEKFKNAEGIIEDDYRIEFIIEHLEWLHK
                     AIEEGSNCVGYHLWTPIDCWSWLNSYKNRYGFISLDLETQKKTIKKSGRWIKEVSKNNG
                     F"
ORIGIN
        1 agcttatcct ctgtaagctt tcctgattca attagtatat ctcctaaacg ctttttctga
       61 taactaatca aagaaaatac ctccttttca agttaaaaat ttaactataa aacttaatct
      121 aaactagtat attaaatttt tcacacacca aaatatattg gtattattat gtttccaaaa
      181 aatattaaaa taatagtaga tattcctata gctggtccaa aggctatata atcacctttt
      241 ttcttttgtt taaacaaaat agctaatact gctattattc caccaataat aaatgataaa
      301 aatatattta ttattgctaa tttccaccct aaaaaaattc ctgctatggc atgtatctct
      361 atatctccac tccccatagc tccagttaat ttactaatta aaaatattac taaagctgat
      421 attactaatc ccataaagta atttaataag ttttctccaa aataaaactt ttctattagg
      481 gcaaaaataa tcccaagtat tacagctggg taagtagtaa ctgcataaac atcttgggta
      541 tcgtaatcta taaatgaaat tactatgaga aatgtaatta agactatgta cttaactgtc
      601 aaaaaagata taccataata tttatataca taaaaatata aaaaacctgt aagcaattct
      661 attagtggat atcttataga tattttgctc ttacaatatc tacactttcc acctaaaaac
      721 aaataactaa aaacaggtac taaatctata ggctttaatt gttttttgca tgtaccacaa
      781 tgtgaaggcg gaaatgctat agattcccct gcgggaattc taaaaataca cacatttaaa
      841 aaacttccaa ttattaatcc aaataaaaaa aatattatag acacattgcc tcccaaatca
      901 tccaaaaatg aattactcat taatatttca taattattat aaacatcttg aaattttttg
      961 taaacatttt tgattaagct ttttttgctc attatacgaa taatttattt tttttattca
     1021 tttaatgttt tgtttaatat tatttaataa ataattaaat ataatctttt taaatactaa
     1081 aaataagggc atgtagtaaa ataagtttta ttattatatt ttatacagcc cctatgaaat
     1141 tactttaatt aaagtatatt tatactatag acaccgtaac ttttcttcca ttttctatat
     1201 ctacattata agagtctcca ctttgaggct tatctaaatc ttcaagtaaa tcttgtaact
     1261 tacttttacc cgtatcatca cttattcctg aaatttgtac atttccatta cttgaagtta
     1321 tttttatatt tgtaacacta cttgaaatag catcttctgc caataacatt tacacagatc
     1381 tttcaatagc agcacaattt tgtttatcta cttttgcctt agcgctatcc ttaacatatg
     1441 aaaaatttgg agctataacc attaaaatta tagccataat agctaaaaca acagttaatt
     1501 ctattaatgt gaatccccct ttcttatttc ttttcccttc atttcctttt ccacatattg
     1561 cacttgcttt cagtaataac atttatggtc ctccttttat attttttaaa gttaaatatt
     1621 ttttaacttt agatttatat tagtattatg gacattttta ccatttatat gcacaaaaaa
     1681 agagattctt taaaagaatc tcttttaata tatcatttgt atatttaatc tcttatgtta
     1741 tttcaagtct taagttatct taaatcttta gtttttttaa atcttttgtt tattttaact
     1801 tatttaagta ctctataaat tctttcgtat ctctctaatg tcttttgttt taatagcaaa
     1861 aactattttc aaatttaact catatgtaac tttaatatct ttcgttctat gaattcattt
     1921 gttagtcatt attttatctt tagtatttat aattcttttg tttttcaaaa atcatttgta
     1981 acttatgtat ttataataac acagtttttc ccagttgtct acaaaataat acaatatttc
     2041 ttattttttt taatatatat tttttatacc aattaaaaac ttaaaattaa tacttttaat
     2101 tacaattaat ttctaaataa cctgttttca taaacttttc aatcactttt tcgacattta
     2161 aaccatttta atcatattat gtaattattt tcaataagaa ttaaataaaa aaaggatgac
     2221 ttaactgtca tcctttttat tcttttatta gtacattccg tccattccca tacctgcgcc
     2281 ttgaggcatt tctttttctg gaatatctgc tacagcagcc tctgttgtta agaatgttga
     2341 tgctactgat gctgcatttt gaagagctga tcttgtaacc ttagttggat caactattcc
     2401 agctttaatc atatctttat attctcctct taaagcatca aatcctacac ctgcatcact
     2461 atttttaact ttttctatta taactgaacc ttctagtcct gcattatgag ctatttgtct
     2521 cataggttct tctaaagatc ttacaattat atttatacca acttgttcat cttgaatatc
     2581 agaggttaat tttgcaactt catttattac atttacgtaa gctgttccac cacctggaac
     2641 tattccttct tcaacagctg cctttgtagc tgctaaagca tcctctattc ttagcttact
     2701 ttccttaagc tctgtttcag tggcagctcc aaccttaact actgcaaccc cacctgctaa
     2761 tttagctaat ctttcttgta atttttcttt gtcaaattca gaagtagtag cttctaattg
     2821 taattttatt tggttaactc tatttttaat ctcttctgag tttcctcttc cattaactat
     2881 tgtagtactt tctttagtta ccttaacact ttcagcttct ccaagcatat ctaatgtagc
     2941 ttcttttaaa tctccgccta cttcatcaga tataacaacg ccacctgtta aagtagctat
     3001 atcttgtaac atttcttttc ttctatcacc aaatccaggt gctttaactc caacacaagt
     3061 aaatgttcct cttaatttat taacaactaa tgttgtcata gcttcgcctt ctatatcatc
     3121 agctattatt aaaagttttt tacctgcttg aactatttgc tcaagtaatg gtaataaatc
     3181 ttgtatattg cttattttct tatctgttat taatactaat ggattatcta aaacagcttc
     3241 cattttttca gtatcagtaa ccatataagc tgatacatat cctctatcaa attgcatacc
     3301 ttcaacaaca tctaactcag ttcccattga tttagattct tctacagtta taacgccttc
     3361 atttcctacc ttttccatag catctgcaat tagcttacca attttttcat cagccgctga
     3421 aattgcagca actctagcta tgtcttcttt tccatttaca ggcttagaaa ttttttgtat
     3481 ttcctctaca gctttttcaa ctgcagtttt aattccattt cttattaata taggatttgc
     3541 ccctgctgtt acatttttta atccttctct tataattgct tgagctaata aggtagctgt
     3601 agtagttcca tctcctgcca catcattagt ctttgtagct acttctttta caagttgagc
     3661 tcccatattt tcataagcat cttcaagttc aatttctctt gctattgtaa ccccatcatt
     3721 tgttattaat ggtgatccaa attttttatc taaaataaca tttcttcctt ttggtcctaa
     3781 tgtaacctta acagtgttag ctaatttatc tacacccgct tgcatagatc ttcttgcttc
     3841 ttcaccgaat aataatgttt tagccatatt aatttacctc ccaaatatat tatgaatatc
     3901 taaatcactt atattttaaa actattcaac tattgctagt atatcgtctt gtcttaaaat
     3961 agtatattct tccccctcga acttaacttc tgttcctgca tatttagaat ataatacttt
     4021 atctcctatt ttaacttcca tctctgttct ttttccatca actatcgctc ctggtcccac
     4081 tgcaacaacc tctgcttctt gtggtctttc cttagcagtt ccagtaacta ttataccgct
     4141 tttagtagtt tcttctgctt ctaatctttt aataacaacc ctgtctccaa gtggtttaat
     4201 actcattaaa aaaccctcct taaaaatgct aattaatttt tgtttagcac tcattaatat
     4261 agagtgctaa ttcttactat tatcatataa tttaccagtt gtaaattcaa taactaaatt
     4321 tatttattta gaatatatta ttattatttt ccatgtttaa ggtaatttat cttaagtttt
     4381 ctgctattct tttgaaattt cttcaattta cttttttcat atatatctct atttattact
     4441 tatttccata ttattatctc ttaatacact acatactata aattaatact aaaatttttc
     4501 ttaaaatatg tatttttgtt taatatttaa taaaaaagtc tagaataaat aaaaataatt
     4561 attttaagga gacataatga ttaagatttt aaaagatata ttattttcat tttaccttct
     4621 aataagttca gtagtatttt ctgttatttt aacattaaat atttctcctg tgctctattc
     4681 cctatttatt aagcttaata taatccctaa gtataacaac cttagcagtg aagaaatttt
     4741 aaatgactat aataatataa ttcattattt aaattctccc caagaagaag ttcttaagtt
     4801 taaaaatttt aaaataagtc ctataggaga atttcacttt ctagaagtta aagaaatttt
     4861 ttcttcaatc tatttaatag gattagcttg cttaatttta ggaataattt tatttataat
     4921 atcaaaaaaa ttcaaactaa aaatatcatt taaagctttt aatattttct tctatgaagt
     4981 tttatttata tttcttagtt taatcttaag cttttactta aacttttcaa aagtctttac
     5041 cctatttcat aaaatatttt tcaataatga ttactggata tttgatccta aaaaagatcc
     5101 aataataaat gttttgcctg aatcttattt tttattttta gcaattttca ttttatctct
     5161 agtaatgata ctttcaataa tatctaaaat attttatact ctaaaaaaac ataaacattt
     5221 aaaataaaaa taatatttaa aataaaatag attaatttaa aaattcagca taaatcttct
     5281 taaattttca aactattaaa gtaacggctt ttttaatttt aaatacatat attataatat
     5341 ttataagtat tttaattatt taaggtgtga tgaatatgaa taaagaaact catatatgtg
     5401 ctctttgtga aagaaaagtt cctaaaatca cagaacatca tctcattcct cgtgaaaaag
     5461 gtggaagatt tgatgaaaca acctggcttt gtgttccttg tcataaacaa gtacatgctt
     5521 tatatagtaa ctatgaattg gctgttaggc ttaattctct tccaagactt aaagatgatg
     5581 aaaaaattaa gcgttactta aaattcataa aaaagcaacc tggtgatgct aatgttacta
     5641 taaaaaaatc aaaagctatt cgtaaaaaag gccgttatta acaaaatgta ctatatcaaa
     5701 ataaaactta caaacaatat aaagagaata tctaaataag ctttagaatt ttaatcctta
     5761 gctaaattta gtaatcctct aaatatgttt gtaagttttt tattagatct ttattccatt
     5821 ttctctagca taatagaata gatattgttg agcaaatcca gaatactctc caaatctctc
     5881 tcttgcaaaa attcttattt tatttaatga agcatcatca gctccataaa aatgcatcat
     5941 tgctctctta acccaaacat ctactgggaa tgcagaactt tttttcatag aaaatagcat
     6001 tatacagtct gctacctttg ctcctactcc cataaattct tgaagtcctt tatgacatcc
     6061 atcagcatcc atattagtta tcttttctaa atcatatttt tctaatattt caactatctc
     6121 ttcttctggt gcatctagta ttcccttttt agctaactca cagttatata tatttttagt
     6181 tgtatcccat atatacttac ttctaaatga agctcctgtc tctcttatat catctattga
     6241 agccttagat aggctttctg gagttgggaa tgaataataa gtatttccct tatactctat
     6301 tggttctccc catctttcac ttattttctt tatggtcttt gaaattacag gaatactatt
     6361 tcttgctgat attataaatg aaataacaag ttcaaaagga tcttgattta atattcttat
     6421 tccatatcca aattcaacag cactctttaa tgtttcatcc caagataaag cttcttttac
     6481 ttttgaataa tctctttcta aatcaaaata atcaacccaa atattttcaa aatcttcttt
     6541 gttagtattg tatattatta catcatggcc ttcttgagct aactctataa cctttccaaa
     6601 ggcaactcct atgtatgaac cactttctgt tctttcccat ctaaaacatt gaccacattc
     6661 aaaaacttgt tttatattaa agttttttgc atcttttaat attactttgt tctctccata
     6721 ttctacactt ttaaaatcca ttcttttcac ctatctttct cttcttacga tttcatctaa
     6781 aacctcagct gcagtttcta tcataactat gcatcttctg tcatcatctt ttttgtactt
     6841 agcttttaag tcagtacaat tatagtatcc caatttatca taaaactttt ccataaattc
     6901 ttgtgttaat gctctagttt gtggactctg atgacctcta tcctctgtaa acataaggcc
     6961 taaaacacca gctgccccag ttgctgctcc acatacattt cctattgcta atcctccacc
     7021 aaaagaagac attactttta aagtttcctt tgataaattt aaattatatt cttcatttgc
     7081 agcgtacatt atgcactctg cacaatttaa atcatgtttc ttatcccact tttctcttgc
     7141 tttttcaact aacatattat cctcctaaat aaagttttat tactataaac ttctatcttt
     7201 tagttattat aaataaaaac tttattttta aaaatacata taaataagat taaacttaaa
     7261 acattaatat tttaaataat aaccttatac taataatatt atactaataa aagttattaa
     7321 taaatagtgt ttttatataa tataaaaaga aaaaaacacg gataggtgtt ctttcgaatc
     7381 accctccatg ttattaagct aagcctttat tgtttttttc ttatcaactt taaaagtatc
     7441 ccaaagtatg cttattgcaa ttaggaccat aagtcctgat attactattg gctttgataa
     7501 aaatactgta acatacccta agaaaggcat atgaaataaa acttttccta ttaagtcttc
     7561 tcctctaact atttcagtat cattagcatt attattatca ccctttgtta taaatccctc
     7621 ttcatttttt tcaacaactc tatgggtaac tactttcccc tcatatttaa atgttattat
     7681 atctccaact ttaacatcct cagcatcaat actcttaaca atagctaaat ctccagtatt
     7741 aatctctggt tccatacttc cacttaatat tgaatatgtt ctaaatccaa cagctttaaa
     7801 tattgaatct gacttactca taaaattatt tactaatatt ataactaaca taaaaataac
     7861 tatgtaatat atagtattaa caatcttttt actattcata aattcaccct tgctaaatat
     7921 aaaatataat tctcctatta tatttatatt caaagattat gtaaagtatt cctatataaa
     7981 aataaaaact gtactaaaag caaataaaat tactcttaat acagttttaa ttaaactaaa
     8041 ttataaatta tgaagattac tataaacacc accaagctta ataagctctt catgtgttcc
     8101 tctctcttct attcctttat ctgttaatac aactatctca tcagaatttt taacagttga
     8161 aagtctatga gcaactacaa gggttgttct atctttgctt aattcttcta aagctttttg
     8221 tatttcatat tctgtaacat tatctaaggc tgatgtagct tcatctaaaa ttaatattgc
     8281 tgggttcttt aagaatactc tagctattga aattctttgc ttttgtcctc cagaaagctt
     8341 aacccctctt tcacctataa atgtatcata tccatcttct aagcccataa taaaatcatg
     8401 tagacatgca ttcttagctg cttctataac ttcctcatct gtggcattag gatttccata
     8461 cattatattt tcttttatag ttcctgtaaa taaaaataca tcttgttgaa ctataccaat
     8521 attttctctt aaagatttta aagtaacagt acttatatcc acatcatcaa taaaaatttg
     8581 accactttca tagtcataga atctaggtat aagattacat attgttgtct ttcctccacc
     8641 tgatggacca actaaagcaa ccattttccc tgcttcaata tctaaattga aattctctaa
     8701 aatactctct ttattatcat atctaaaagt aacatctttt attgtaatct ttccttttac
     8761 atccttaagt tcctttgcat taggaatttc tttttcgttt tcctcattca ttatctcttc
     8821 atatctttca aaaccagaca ttccattttg gaacatttca ttgaaattta taagttttct
     8881 aataggctgt aagaacatct ttatatatag taagtatgct gcaaaatccc ctacatttat
     8941 ttttcctaag taagtaaaat atccagctgc tattaaaact ataagttcaa gcatatctac
     9001 aaggaaaaac atccctgaaa aatattcagc cattgcctta taagcatgtt ctctagcttt
     9061 cttaaagata ccattactct tatcaaactt ttccatttca taagacttat tgccgaaaga
     9121 tttagttact ctaactcctg aaatactatt ttctatagta gcatttactt caccagtttt
     9181 aactcttgtc tctttaaatg cttttttcat tttatttctc ttatgaatag tataaaaaag
     9241 taaaaaaggt attatagcaa aagtaataat tgttaaaggt acatttattg tacataaaat
     9301 tataaatgat cctactaaca taactaagga tataaataaa tcctctggcc catggtgagc
     9361 taattctgat atatctagaa ggtcatttat aattctagac ataataactc cagttttatt
     9421 attgtcaaaa tacttattag gcatatcctg tagcttatca aataagtctc ttctcatatc
     9481 agcttgcatt ctaactccaa ctacatgtcc ccaatattgc ataaaatagt ttaagcctgc
     9541 cttaattaag aatattagag taagtacaat tgcaaaaaca aacaataatt ttatctgctt
     9601 atttggaata acatcattaa ttatatttct tgtaatcata ggataaaata aatcacaagc
     9661 tgaaactaaa aatgctgcta ataaatctaa aataaataat tttttatatg gtttataata
     9721 acgtataaat ctttttaaca tactacctcc ttttaatgat aaaaattatt aattaacacc
     9781 aattttcatt cttttaatta taatgaactt tctaaattaa atcaacctga taaaattatt
     9841 taaataaaaa gctttttata aaagaaaaaa gagattgata aaatatcaat ctcttacttt
     9901 acttcaatct cttcctataa tatatacttt aaaatattta ataatatcag atttatacta
     9961 tagaaaattt ataccttata aactttttaa actttcaata ttatgcgttg tagttgtaga
    10021 atcctctacc agtttttcta cctaaccatc ctgctctaac atattttctt aaaagactgt
    10081 gagctctgta tttactgtct ccagtttctt taaataatac gtccattata gctaagcaaa
    10141 catctaatcc tattaaatct cctaaagcta aaggtcccat tggatgatta gctcctaatt
    10201 tcattgaagt atctatatct tcaactgaag ctattccttc tgcatatatt ccaatagctt
    10261 cgtttatcat agggataagt attctattaa ctacaaatcc tggtgcttca gcaacttcta
    10321 ctggagtctt tcctatagct tctgacatag cttttacttt gtcaaaagtt tcttgtgaag
    10381 tagccatacc tcttattact tcaacaagtt tcattattgt tgcagggtta aagaaatgca
    10441 ttcctataac tctatcaggt ctgtttgtag ctgaagctac ttctgttatt gataatgaag
    10501 atgtatttga agctaatata gtttcttctt tacagatttt atctaattca gcgaaaattt
    10561 gttttttgat ttccatattt tcaactgcag cttctataac taaatcacaa tcagcagcca
    10621 atcctaaatc agtagttcca gtgatttttg ataatactgc ttctttatct tcttcagtta
    10681 tttttccttt agaaactaat ttagtaagac ctttattgat tccagctatt cctctatcaa
    10741 caaactcgtc tttgatatct ctaacgataa cttcatatcc tttttgtgca aatgcttgaa
    10801 ctattccagc acccattgta cctgcaccaa ttacaaaaat cttttccata ttaagttcct
    10861 cctaaatact ctctttaatt ggacttttct gacttaacag aaaagcccta caccattaat
    10921 tgaaaaattt tataagttta cccttgttat attatttatt aattaagctt cttccttcat
    10981 agcttttaat tgagctatga attctggaac aactttattt acgtccccaa ctattgcata
    11041 gtcagcaatc ttcattattg gagcattagc atctttattt atagctatta tcatatctga
    11101 atcttgcata ccagcggcat gttgaatagc tcctgatata ccacaagcta catatatatt
    11161 tggtctaaca gtttttcctg tttgtccaac ttggtaatct ttatctaccc atcctttttc
    11221 tactgctgct cttgaagctg cgattgatcc attcataact tctgctaatt ccttaagcat
    11281 tttgaagttt tcttctgaac caatacctct accacctgca actaatacgt tagcttctga
    11341 tatatcaaca atatctttat gttctttaat tatttcaaca atttttgttc ttatatcatt
    11401 agagttgaat tttatttcaa cattttctac agttgcatca ttttctccta gtggaagttt
    11461 ttcaaaaact ccaggtctta ctgtagccat ttgtggtcta tgatctggac atacgattgt
    11521 agccattaag ttaccaccaa atgctggtct tgttgctaat aaatctccac tttcaacatc
    11581 aacatctaaa gatgtacagt cagcagttaa accagtttct aatcttgcag caactcttgg
    11641 acctaagtct cttcctatga atgttgctcc tatgaaaatt atatttggtt ttttagcatt
    11701 agctaattca catatagctt ttgtatatcc atcagttgtg taatgttcta attctggagc
    11761 atcaacaact agtacttcat cagcaccatg tcttgataaa tcttcaacta aattttgaac
    11821 tttatttcct attaataacg ctgttaattt tgatcctaat ttatcagcga tttttctacc
    11881 ttcacctaat aattctaatg aaactttttg taattgacct tctctttgct ctgcaaaaac
    11941 ccaaacgcca ttgaaatctg ctttattcat cttaaatacc tcccataatc cttagatgta
    12001 gtgtttttct tttaatttgc ctagtacata agtaactgaa tctttaggtg attctttaac
    12061 tatttctcct gcacctttag cttctttagt cattgatctc ttaacttttg ttggagatcc
    12121 ttttaatcct aattcagctt tatctacatc tatgtcatca gctgaccata ctaagatttc
    12181 atcatcagat gtttcaaata tatttttaac attcatgtat cttggctcat ttaactcttt
    12241 tatagcagtt aaaagtactg gagctttaac ttttattaat tcatatccat cttctaaagc
    12301 tctatttact aataatccat cttcttcaac tttaacgcct tgaacataag ttacttgagg
    12361 aatatttaaa tgttcagcta tttctggacc aacctgtgca gtatctccat cgatagcttg
    12421 tcttcctgcg aatattatgt catattctaa tttctttaat gctccagcta aagcctttga
    12481 agtagctaat gtatctgcac ctgcaaatgc tctatcagtt ataagaattg ctttatcagc
    12541 tcccatgcat aaagcttctc ttaaagctga tttagcttga ggtggtccca tacttaatac
    12601 agttacttct gctccattat tatcttttaa ttgtaatgca gcttctaaag catgtttatc
    12661 ctctgggttt attattgatg gaactccatc tcttataaga gttcctgttt ttggatctat
    12721 tttaacagct gttgtatctg gcacttgttt taagcaaact actattttca tctcaaagcc
    12781 ctcctaaaat tatcttaata tgcttcctgc gataaccatt ttttgaactt ctgaagttcc
    12841 ttcataaatc tcagttatct tagcatctct catcattctt tctactgggt attccttagt
    12901 atatccatat ccaccgaata attgaactgc cttagttgta acttccatag ctacatctgc
    12961 agcgaataat ttagctcttg cagcatctat agaatatggt ttaccctctt cttttaaaca
    13021 agctgcttta tatactaaaa atcttgcagc ttctatttta gtatccattt ctgctaccat
    13081 ccattgtaat ccttggaatg cagataatga tctaccaaat tgttttcttt ctttcatgta
    13141 agcaacagct tcttctaaag ctccttctgc tatacctaat gcttgagcag cgatacctat
    13201 tctaccaccg tctaaagttt tcattgctat tccaaatcct tttccttctc ttccgattaa
    13261 gttttctttt ggaacaacac agttttccat gattaactca gttgttgaag aagctcttat
    13321 acccattttt tcttctaact taccaattga gaatcctggg aaattctttt caactatgaa
    13381 agctgaaatt cctcttgtac cttgactctt atcagtcata gcaaagatta tgaaagtatc
    13441 tgcaactcca ccattagtta tgaagatttt acttccgttt aagatgtaat tatctccttc
    13501 taatacagct gtagtttgtt gtcctgcagc atctgtacct gctcctggtt cagttaatcc
    13561 aaaagcacct aatttttcac cttttgcaag tggagttaaa tatttttctt tttgagctgg
    13621 agtaccaaat tgatctatta atgaagcaca taatgaagta tgagctgaaa ctataactcc
    13681 tgtagtagca caaacttttg ataattcttc aacagttaag atgtaagata aagtatctcc
    13741 accagctccg ccatattctt tgctaaaagg aattcccatc attcctagtt tagccatttt
    13801 cttaacattt tccataggga atctttctgt tacatctatt tctgcagcta taggcttaac
    13861 ttcattttga gcaaattctc taaccatttg cttaactaat tcttgttctc ttgttaattg
    13921 aaagttcatt tttaattacc ctccttaaat ccacacaacc attttgttta aaaaattact
    13981 tgtttttaaa gttcttttct cttctctcta caaaagcact cataccttct gtttgatctt
    14041 ctgtagcaaa acattttcca aaatcttcag cttctataac tacagctgaa tctatatcaa
    14101 cttgcattcc tctattgatt gcatctttac ataacttaac agctattggt gcattattag
    14161 atatcttctt agctaatgcc attgcttctt ccattaaatt ctctggttca acaaccttat
    14221 ttactaaacc aattcttaaa gcttcatcag cttttatcat gtctcctgtg taaataagtt
    14281 ctttagcctt accaggtcca actattcttg gcaatctttg agttccacca aatcctggag
    14341 ttattcctaa tcccacctca ggttgagcaa acttagcctt tgtagttgct attcttatat
    14401 cacaagccat agaaatttca catccaccac ctaaagcgaa accgtttata gcagcgatta
    14461 caggcttgtc taaattttct aatcttctaa acactttatt acctaaaagt ccaaattctt
    14521 taccctcttc ttcatttaga tctttcattt ctgctatatc agcacctgca acaaatgctt
    14581 tatctccagc acctgttaaa ataacaacat atatatcatc ttgtttttct atatgatcta
    14641 tagcagtatc taagtctttt aaagtttctg agtttagtgc atttaatgcc ttaggtctgt
    14701 taattgttaa aaccccaatg tttccctctt tttcaaagat tacattattt aattccattg
    14761 tatttcctcc ctcatatacc atagcgaata tatggtttta aataacttaa caactaataa
    14821 ctaacaactt aatatttttt atcctatgct tcttccagaa tttattgtta attttgtaac
    14881 aagcaaagac aaaaaaataa ttgaagtact cggtacttca attaaattat aaaacttaaa
    14941 agtaaatttt tcaatatatt tttttgaaaa tctaatacta tttttccata ttaaacaaat
    15001 ttttataaaa taaatccaat ttattttaca tcattgtgat ttaaaagata tactaaagtc
    15061 atcatacttt cacttaaatg tacattctct actcttatat cttttggcac ctcaagatct
    15121 ataggcgcaa agttccatat acctttgatt ccaccttcaa caaggtcatt acataccttt
    15181 tgagcatttg ttcttggaac acagattata cctatttcaa tatcattttc ttttacgaaa
    15241 tcttttaatt tttcaacatc ttgtatctca acatctctta tttttattcc aaacattctt
    15301 ggattagcat caaaaatacc ttttaattta aagcctaatc tattgaaact attgtagttt
    15361 gcaatagcct gccctatgtt accagctccg attataactg tgttataatc tcttgtaagt
    15421 cctaatatac tccctatgtt attgtataac tcttttacat tatatccata tccctgttgc
    15481 ccaaaatctc caaaacaatt aagatcctgt cttatttgag aagcagtgaa gcctattttt
    15541 tcacttaact cttttgaaga tattctatca acatcatttt ccattaattc ttgtaaatat
    15601 ctatggtatt taggcaatct ttttataaca gccatagata tgcctttttt cttttccatt
    15661 ttaatagcac ctctttctaa aattgttctt tttttaaaaa gcaattactt tttagactgt
    15721 attctaaaat caaatgataa aattacaaat ttaaccttct aaaatattac cataccctaa
    15781 aaagtttgtc tatattttaa cattcttttg gtttcactat caaaaatata tgtattaaag
    15841 tgtatttttt acatttaatt gcatttttta tatcattaat taatattatt aaatttatgt
    15901 gattctatta taaactatct ttctaataaa tttctacaaa aaaaataagg cttgcgtggc
    15961 taaaacccta cgtgcacaca agcctattta aacatttcat aatgtttaat ataaaagttt
    16021 aagggaatta tttacaatct ataccctatg cctgaaagta ttcttaccat attaagatag
    16081 caaaaaaact agctcttgtc aacaacatta gacaaatttc acgcctataa atttttattt
    16141 tttaatatcc tacttgaatt tattactgct attaatgtta cacctacatc tccaaataca
    16201 gcttcccaca tattagccat tcctaaagca ccaaatatta atattataat tttaacacct
    16261 aaagcaaaga ttatattttg ccatacaatt ttatttgttt tcttagctat ttttattgct
    16321 tttattatct tacttggctt atcatccatt attaccacat ctgcagcttc tatggctgca
    16381 tctgatccaa ctccacccat agctatccct atatctgccc tagctagtac aggtgcatcg
    16441 ttaattccat ctccaacaaa agcaactttt ttacctttgc tcttatcttc aaaaatttgc
    16501 tctaattttt caactttatt ttgtggtaat aaactacaat atgctttatc taagcctaat
    16561 tctttggcaa cactatctcc aaccttctca ttatctccag ttagcataat tgtttgctta
    16621 actcctattt cttttaatcc acttatggct tctttagaat cctcttttat ttcatctgaa
    16681 ataactatat atcctagctc actcttttca tttgctaaat aaacaacagt acctatttca
    16741 tgaattggag taatttttat attaaacata tccattaatt tggaattacc tgctaagaat
    16801 gtttctccat caatgtctac ttttattcct tttcctgaaa tttcttcata atttgaaatt
    16861 aagtctttgt tgatttcttc attaaactca cttactatag atttagcaat tggatgattt
    16921 gagtaatatt ctgcataagc tcctaacttt aataattctt cattagttaa cttgcttgtg
    16981 ctctctgatt ttctaacttt aaatgtacct tttgttagtg ttcccgtttt atcaaaaact
    17041 atactctcta cattatttag tgcctctaaa tagttacttc cttttattaa aataccattt
    17101 ttagaagcta aaccaattcc agcaaaatat ccaagtggta ttgatactac taaagcacaa
    17161 ggacatgaaa caactaagaa tattaaagct cttgaaatcc atggagaaaa actttctcca
    17221 cttattacta aaggtggaat aattgcaagg gctaaggcag agaatacaac tactggtgta
    17281 taatatcttg caaacttagt tataaatttc tctgttggtg attttttatt tcctgcattc
    17341 tcaactaaat ctaatatttt agaaactgta gattctccaa aactttttgt tacttttatt
    17401 tttaataatc cacttttgtt tattgatcct gctaatacat cgtcttttgc ctcaacttct
    17461 tttggtaaag attctcctgt taatgcagat acatcaagag ttgcctctcc tgataaaact
    17521 actccatcta gaggaacttt ttctcctgct cttaccacta tgattgatcc aacattaacg
    17581 ctttctggag atactctttt ttcctctcca ttaagatcaa ttaaatttgc aaagtctggt
    17641 cttatattca ttaaatcaga tattgatttt cttgatttat ttacagcata gtcttggaac
    17701 atttctccta cttcatagaa aagcattact gctacccctt ctgggaattc tcctatagca
    17761 aaagctccaa ttgtggctat agccatcaag aagttttcat caaatacttg tcctcttaaa
    17821 atattcttaa atgctcttaa aagaacttct ccacctgcta taatataagc tacaccaaat
    17881 ataataaatt catacatttt atctaaatta actatcattc ctattataaa taaggttaaa
    17941 gctattccta gtctaaaaag ttccttcttt tctatacctg agtttcctcc atgactatga
    18001 gaatgcccat gttcatgaga atgtgagtga ctctctacat tattgtgttt atgagattct
    18061 ccttctccac agcatccatc attacatgta ttaactgaag attttatttt atttttatcc
    18121 tttaaaactt tcacatctgg ctctaaatct aaaactattt tttcaacttt ctcttctaat
    18181 tctttttctg aaaccccttc tttaggagtt ataagtaaaa gttttgttga aaaattaagg
    18241 acagcttcat caacatcagt aagtttatta actttatctt caattttccc agcacagttt
    18301 gcacagttta agccgtctaa ataaagcttt atatctttca tgcctaaata cctcctttac
    18361 tctaaaacgt gatttaaacc ttcattgaat atgtgtttaa catgatcatc atctaaagaa
    18421 tagtaaacta tcttaccttc tcttctaaac ttaactagcc tagcttgttt taaaactctc
    18481 aattgatgag acactgctga ttgacttaca cctaatagtt cagccatatc acatacacac
    18541 atttctcctt caaaaagggc acataaaatt tttattcttg ttgaatctcc aaaaacttta
    18601 aatatttctg ctaattcata aagtacttct tcctttggca aatgttcttt taccctactt
    18661 aatatatctt catggatata agaacagtta caactttcta ttttattatt atccatattc
    18721 ttaactccta ttattcattt ttacatatga gcatctgttc atatgttcac ttttattata
    18781 tgtctctttt acaaaaaatg caactaaaaa agggcgtata tcaaaataac tttttataaa
    18841 acttacaaac agtatgaaga gaatatctag atgagcttta gaatttaaat tattacgtag
    18901 aaaatttcac gttaaaaagc tgagactgtt cgaagcgtag caagtttcga agctttagtg
    18961 atattttcga agtaattatt ataaattctt agcgaaatct agtaattctc ggaatatgtt
    19021 tgtaagtttt attattatat tttaatacag ccctttttcc attatttatt taaaaacatt
    19081 tctatctttt ttaatatgtc ttcttctcca actacaagga gattatcatc tttttcaaac
    19141 tttaaatatg gtcctggaga tattataagc tctccttttc ttcttatagc aacaatagta
    19201 gcttgtgtat tttgccaaaa cttcgactct gaaacactct tacctataag agtacaatcc
    19261 tttggtaatt ctatttctat aggtgttaaa ggatttgtat atctaagtct gttagagtaa
    19321 tccactattt tatctatcat ttcacctata tttttttcta tagccttttt ttcttccatt
    19381 aaggattcta tatcatgttt taaagatgtt acactttcaa ttgaatgaaa cctatttatg
    19441 aaattataag cattatcttt tgaaataatt gttactccgc tacccttgct tgatgatact
    19501 actttcatgt cttctaataa tttaacagct tttctaactg tttctggtga tacattgtaa
    19561 ctacttgcta aagttgatct accatgtatc ttttgtccta cctttatgtc attattatat
    19621 atcctacctg caatatctaa agcaatttgc ttatatatag gttcatttac cttactctcc
    19681 atctcatttc ctttctatta taaaaattac tttaatcaat atatataatt gattttaaca
    19741 tattttatca tctaaaggaa atatttgtat taagctatag cttcagaata gactgccttt
    19801 gtatttctag ctatgcaatc acttatatat ttaactatac ttctacatgc aaagtatgca
    19861 tattgcatat cattctcata actttctctt tttctatata acttatgagc ttcttctaag
    19921 aaaaacttca cagacatatt accccatatt ttaaaatcat cctgtgatgg agtatatgtt
    19981 ttagcaaaac tagctaactc tttttcgtat ttaacatgtt tattcatact atgcttaaat
    20041 tcccatcttt cactatgagg aatacagaaa aaatcacata taaagtgaca tataactcct
    20101 agttcctgac taaatctact aactgaaaat ttctttttaa aatcatacat actaagtgat
    20161 gctaattttt ttatcttatt aactatcata tcaaaagatt catctaaata atgcttcttt
    20221 aatttatatt ttgaaaccat atcaggtttt acatttccat atataaagtt tttatcactt
    20281 attttaaaat ctacgtcaac atctctcaat atattttgtg caataagaat atgagtgttc
    20341 attaacataa tttattacct ctaatctctt taaaaaagtt tcttattaat atgatatttc
    20401 atatcaatta aaagtatatt acaaaaacac cttaaattta ttaattaatt attaataaac
    20461 ggtttattta ttgtatgaaa tgcttcctac tctacagttt taacccaatt tacctattta
    20521 attcttaaaa ttattacatt ttaaagataa ttattattta tattccaatt ttgctttttt
    20581 atatcgtaat gcttaagaga agatttcttt taatatttac tctatttaaa ataaatttta
    20641 attttaaaaa aaaactattt ttctataaaa aataaaagtg cctaaaatta aaaagctagg
    20701 aatgaaaaac ttccattcct agcttataaa atacaaatta ataattatat tgtcctacat
    20761 tttcacaaat tcttatatct aaaagatcat ctgaaagagt ttttttgtat gaacataaga
    20821 actcatttaa ttcactatcc tgaagatcta tatttttagg actagttata agaactttat
    20881 tattttctaa aattaactca atatcatttt tttcgttttt aataaaatat gtagtaacag
    20941 tagatgtttt tacttttccc ttatacttct cttgaaaact caaagttttt cttaaatttt
    21001 cataatctcc accttgaatt cctaagttac tcatatctat acctaagttt ttcatttgcc
    21061 cttcaatatc acccatatca aagccatatc tcttaagcat ttctgtttga atatttaaaa
    21121 acttttcttg agaaatatta ttttcattca tatatttagt tatctctcta gaaagctcca
    21181 tcatactcat ttttccttga gctactgaat aatataaatc ataaatatat gactcaaatt
    21241 tatctatatc tttatctctt gccttatttt ttaactcatt aaaatctaca attctatcac
    21301 tcataaaaca atacctccgt aaagttcaaa cttatattat tactataata acataaaaat
    21361 atctttataa catattttaa ggattaaaat tagttatatt ttaattaaat ttaaatttta
    21421 aataatttta tgttttctta actaaattgt agatattaaa agcaactaaa aagtcctata
    21481 tcatacacct aaagtatatg atataggact ttttttacat aagtttataa acttatagat
    21541 attctttaaa ttccttctta ccactaatag aatttaatag atgcttaatc tcttggtccc
    21601 tacctttgtc catgaccaaa ataacatctc ctgcatcaac taatactaga tcttttattc
    21661 caaatcctat tattaatttt tcctttccaa aaacggaaca attctcacat tcctctaaaa
    21721 aaacattatc tgaagttcta ttatttccat taggtcctaa aaatctactt agagctgaga
    21781 aagtacctat atcatcccaa gaaaaatcac attttataac aaaggatctt cttgtttttt
    21841 gcattactcc aaaatctata gatattccat caattaaaga atactgctct tttattattt
    21901 cttcctcatc atcttctcca atgtgttgat atatctccat taaacattta tacatcttag
    21961 gaatatattt ttcaatttct ctcaatataa catcagctct aaatatgaac attccactat
    22021 tccataaata agtccccttt aataagaagt cctttgctac ttctaaatta ggtttctctg
    22081 taaaccttgc tatcttgaag gtaggaatgt gtccattgac tctatcgccc atttctatat
    22141 agccataacc tgtctctggt ctagttggct ctattcctat ggtaacaata gctctcttct
    22201 tatccgcaat ctctacggct tgttccagag tttgaagata acttttatct ccttctatat
    22261 aatggtctga aggcaataca atcataactg catccttatc tttctttaaa agcttagctg
    22321 ctgaaagacc tatacaggtt gcagtttctt tattagcagg ttcagtaaag atattttctt
    22381 ctcttatgtc tttaagttca tctcttattt tgtcttcata ttcctggttt gtcactacat
    22441 aaatattatc tttatggatt ataggtctaa ttctatccac agtattactt aaaaaactct
    22501 tcccattatt gtgtatgcta agaaattgtt tagggtttga acttcttgaa agtggataaa
    22561 gtctagtacc ctttcctcct gctaaaatta atgagtaaag catgttgcct tcaactccgt
    22621 taattgttat agtgtatttt atgtgaaaat atcccattat gtgagtatta aaaaaattta
    22681 aggctttagt ttaagtaaaa ataccataac taaagccttt cctcatttat tcatattaat
    22741 ttattttatt tataatttta taataaaaaa ctttttgcgt aatcatatta acttagaaaa
    22801 tttattttag aactgatcta agctaattaa attcaaagtt ttaaaaacca ttattcttag
    22861 aaacttcttt tatccatctt cctgattttt taatagtttt cttttgagtt tctaaatcta
    22921 atgatataaa tccatatcta ttcttatatg aatttaacca tgaccaacaa tctattggag
    22981 tccataaatg atatcccaca caatttgaac cctcttcaat agccttatga agccattcta
    23041 aatgctctat tatgaattca atcctataat catcttcaat tataccttca gcatttttga
    23101 atttttcttc tccttcaaca cccattccat tttctgaaat gaaccatttt atgttgccat
    23161 agttatcttg cacattttta gctatatcat aaattgcctt aggatatatt tcccatcctc
    23221 tatggggatt cattctcttt cctggcatat cataattatc aaaatatttt tctggagccc
    23281 atgtttctcc aacatattcc tcttctctag ctttaactct tcttggttga tagtagttta
    23341 cccctaagaa atccacagta ttatttttta taacctctaa ttcttcctta gtagaattcc
    23401 acattactcc atctttttct aaaacctcaa ctaagttctt aggaaattct cccttagttg
    23461 ctggatctaa gaataactca ttgaagaaag cattggcaat ttcagccgct cttaaatctt
    23521 cctttgactc acttcttgga tatgctgggg ttaagttaac tattattcct atttctccat
    23581 cttgtcctaa ttttctatac tcttctatgg ctctagcaga agctaatgct atattatagg
    23641 cagcttgaag ccctcttttt ccatcaacta tacaaggata atgccattta tataaaaact
    23701 gtccttcaat aataactata ggttcattaa atgtagccca ttttttaacc ctatcaccaa
    23761 ataaactaaa ggcagtctta gcaaatttcg caaataattc tacgacatgc tttgattccc
    23821 atccaccata tttatcatat aattcaacag gaagatcaaa gtgatgtaaa ttcatgatta
    23881 tatctattcc atttgctaaa cattcatcta ttacaccatt ataaaatctt actccatctt
    23941 catctggctc accagtttca aaatctttaa ttaaccttgt ccattgaatt gaagttctaa
    24001 aggaatttaa tccaatttct tttagcattg ctaaatcttc tttgtaacta ttataaaaat
    24061 ttgatgctat atttggtcct ataccattgt gaaataactc tggatttata tcgaaccagt
    24121 gatcaaatac attatcatgt tttttattaa acctaccttc tgactgaggt cctgaagttg
    24181 cagctcccca ccaaaagttt tctgggaaag tatatttcat gtgaaaaccc cctatacctt
    24241 tgtaaacttt ttctctactt aattgtatat tttaaaaaaa cttttttcta gggttcttat
    24301 atggcttaat tccaaaaaaa gtggttaatt tcaagaaaaa aagatctaag tataacttag
    24361 accttttttc gcaaaccaat attataaata taactgtata aattttaatt taaactcata
    24421 acgtcccctt taaatgacca tacttaataa attctctcaa aattcaataa taaaaataat
    24481 ttctcaatat aaatacccta atatctattc ataagtcgaa agatattcta gcttcttccc
    24541 cgtcgaagct tataaaattc atgtaagaac aatttcttat tcttaagttt aaaataaaat
    24601 ttactcatat tttcaatagt aatcgtacta gaaggctccc ccaaacctta aagcttaaaa
    24661 acttaatctt aaatatgctt atcataccat tattggcttg tcagaagttc atctataaat
    24721 aacaggcatt agtacataga cgtaactttc aaagattg
//
