LOCUS       NZ_CP075979.1          23989 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP075979.1 Clostridium perfringens strain CPI 18-6 chromosome.
ACCESSION   NZ_CP075979
VERSION     NZ_CP075979.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:44:31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 672275
            Orig. end    :: 696264
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23989
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[682275:686264]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13989
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..23989
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..23989
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="3"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     protocluster    1..23145
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[682275:685420]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10001..13145
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             756..1169
                     /locus_tag="ctg1_545"
                     /transl_table=11
                     /translation="MYVAFGNRVLDSEDIKKEIELNTDARVVSDLCKSSKREDIIAFKL
                     SIDMDILRGLMKENSDLKDLNDEELFEDYLDLAEEVAGMIFEYMPEDAILDIRSYKWDM
                     SYNDVKLIMVMAHEDLGIAKVNDVMKRLLRQVD"
     CDS             1480..2595
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     229.6; E-value: 1.6e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_546"
                     /sec_met_domain="Fe-ADH (E-value: 7.5e-69, bitscore: 229.6,
                     seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLSLNTEILGFDTSSEFAKELNLNEKDLVFTNRRIYEGSFKSL
                     DLKCNYVLKDKYNFNEPNDEIIDEIFKDIKNIDFNRVIAIGGGSILDVGKLLALKDVSS
                     TKKLFKRELPIIRDKELIIVPTTCGTGSEVTNISIVEIKSENTKLGLAVDELYADKGVL
                     IPELCKTMPYKAFVYSSIDALIHSIEGFLSPNSTPYTDLFAFKAIEMILSGYKEIIEKG
                     EEYRNTIMDKFLIASNYAGIAFGNAGVGAVHALSYPLGGKYHVPHGEANYQFLMAVLNF
                     YKKNNGDGKISELTKLISSIINAKEEDCYLELENLLNNLIRRKNLKEYGMTIDEIEKFS
                     QSVMKNQQRLLKNNYVSMEIKDMEEIYKSLY"
     CDS             2604..2792
                     /locus_tag="ctg1_547"
                     /transl_table=11
                     /translation="MKFFRMILIAGEVLLVILLLLGIVFKVAECEKKDKSLSNIKEQHV
                     KLDDEQQEKLLYCSIIR"
     CDS             2828..3508
                     /locus_tag="ctg1_548"
                     /transl_table=11
                     /translation="VVLVLTFILFLMIFLIIVDFFAILFRLTGVPIEKARFQVTSLLTG
                     TGFTTKESEIIVQHPTRRKLAIWLMGFSYASTATIISFAVNIITSSVIDVGSIAVIVLF
                     IIFVLFFHKSSLLEKFENKIEKFIVQSKIWDKINSKHLTLITNTKGFGVYEIYLSNKAT
                     LIGKSIRDSDLKSNEIEVLNIDKGDKFVNFPTPDYTFEVCDKVTVYGNVKNIKAMFKHI
                     NEVK"
     CDS             complement(3623..4075)
                     /locus_tag="ctg1_549"
                     /transl_table=11
                     /translation="MDLKALNPNGNAFLVSFTKAKKTYKKFISPTLNDLGLTHNEFEIL
                     VFLQENLEYNTAKDIVEFSGLSKGLISRSIESLLKKEMLSIKKDDKDKRIFRLYISPSA
                     NETLNVLNKVSNRFFKLLLEDLKDEELMFFDEVLNKMIKNLNNLKI"
     CDS             4329..5462
                     /locus_tag="ctg1_550"
                     /transl_table=11
                     /translation="LEFKNNKIKDYIFLSTYIILLIFFFINIKDIMNFLYKFLGILKPF
                     IWGIAIAFILNIPVKLIEKNLGNSKFFKGMKRSFSITLTFLFFILAITLFILFVIPQLL
                     SSISTLMNSIPEYLSQFEKFLEVNAINNSQSQVMMQNIINELLNMWKEILKVTSQIVGT
                     SLGYLLDFTLGITYGVINFFLSLILAIYMLASKEILISQLKLIIYAFVSKNKADRIIEL
                     GKMCNEMFSKFILGQCTEALVIGVLCFIGMIILKMPYALLISVVIGVTALIPVFGAFLG
                     TIPSAFIILIIDPIKALWFIIFIIVLQQLEGNLIYPRVVGSSIGLSALWVMFAMIVGGS
                     LFGIIGMLIGIPIFGVVFKILKRVANRKINEKGIERR"
     CDS             5867..7258
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 86.6; E-value: 5e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_551"
                     /sec_met_domain="MFS_1 (E-value: 2.3e-25, bitscore: 86.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAIKSTDFEVEKGNGRLKHPAGLYLLFFTEMWERFSYYGMRAL
                     LMLYLTASFVTGGLGYDVPSAARIYGAYTFLVYFTPIIGGEIADKFLGQKKSIMLGAAV
                     MILGNLTLFGWQTRWALYLGLGFIIVGNAFFKPNISTIVGQLYEDGDKRKDSAFTIFYM
                     GINLGSLIAPIICGLLAENFFATKSGEVILHYGFRYGFLAAGIGIILGEIIFITLSPKY
                     LAHVGEIKREKNKKDVAKEKKPLTKQEKKRVAVILILASFVVFFWAGFEQAGTTLTLFA
                     ENATNRSLFGWTVPVAFFQSINPLFILILAPLFSKLWFTLANSKRGDLSIPTKMAMGMI
                     VLGCGFLLMVFATMSLGGNVENPAVKASMFWLVGTYLFNTMGELCLSPIGLSMVSSLAP
                     AKYASLLMGVWLASNGVANYLSGFIASFVEKLGALELFGSIAGVSIVLGLVLLLLSKKI
                     TAMME"
     CDS             complement(7420..7635)
                     /locus_tag="ctg1_552"
                     /transl_table=11
                     /translation="MSDNKLKEDLVKVYKEWKDLEKKAGKKIKHHHELKKEEKEDEIQR
                     FSDYAGLSVPITEEMLLYLDEEYFRV"
     CDS             complement(7649..7879)
                     /locus_tag="ctg1_553"
                     /transl_table=11
                     /translation="MGEEKIKKELLDLYSKWRVSEKSFFEKLKLNHDFKKLEKEQIKLI
                     TKKFSEFAKIDTPLTEKEILELEEYYNNTFI"
     CDS             8129..9679
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NIR_SIR_ferr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NIR_SIR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_554"
                     /sec_met_domain="NIR_SIR_ferr (E-value: 3.1e-12, bitscore:
                     43.6, seeds: 171, tool: rule-based-clusters)"
                     /sec_met_domain="NIR_SIR (E-value: 5.2e-33, bitscore:
                     111.2, seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLNDILSKEIEEFREKGHKFLNKEMTVGEFKKASGGMGVYAHR
                     GGKEFMVRLRVPSGVAGLSLLEEAYNWAKKYNLEKIHLTTREAIQLHGISIDAVCDIMQ
                     EGLTKGIYTRGGGGNFPRNVALNPLSGVQIGETFDVTPYALASNAHYMSKIYTYNLPRK
                     IKTAFSNTEEDSAHCTVTDLGFLAVENNGKRAFKLYIGGGLGRNPRTSVEFDELIDEKD
                     VLYCLEAMTNLFVAEGDYKNHGKARIRYIVERMGEEEFKNCFRKHLEEVKAKGGLDLKV
                     EDIKYSKKGEKTNIKHERLIPQKQEGLYTVLFHPVGGQLSLDVLKELIEKIEKIEEVEV
                     RLGMDENLYVRNLNGKEAEAILDFTQGKGGETLAERSVSCIGTPICQMGVLESQKTLRE
                     FVELLKENSIKEGILPRVRFSGCPNSCGMHEIGDIGFAGKKKKVGDVLSNVFELHFGGK
                     LGIGETRLGDYYGDILQDKVPEFLIKVAKAVEAKNSTFEEWIKDNSEEFKAIVEEYNV"
     CDS             10001..10807
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_555"
                     /sec_met_domain="AdoMet_dc (E-value: 2.6e-28, bitscore:
                     95.8, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKEKICLYGFNNLTKTLSFNIYDICYAKTEREKEDYIKYIDEQYN
                     SERLTKILCDVTEMIGAHVLNISKQDYEPQGASVNVLITEEALPVALIDPSCNKGEISY
                     LELRDSVVGHLDKSHLTVHTYPEFHPNNDIISFRVDIDVSTCGKISPLNALDYLIGSFD
                     SDVITIDYRVRGFTRDVDGRKCYIDHDIKSIQDYIDGETLKKYDAMDVNVYQSNIFHTK
                     MMLKDIVLNNYLFNSDPYELSPNDRREIRDRISKEMIEIYGGVNIY"
     CDS             10825..12279
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_556"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.7e-09, bitscore:
                     35.5, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 8e-135,
                     bitscore: 446.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKRLSQENAPIYEALKWYKNQRIVPFDVPGHKQGRGNTELREFLG
                     EDCVSVDVNSMKPLDNLCHPTSVIKDAEELAAEAFGADKAFFMVNGTTSAVQAMIMSVC
                     KDGDKIIMPRNVHRSAINSLIITGVTPVYINPGIHGRLGISLGMAMEDIKKAIKENPDA
                     KAIFVNNPTYYGICSNLREIVKLAHENNMYVLVDEAHGTHFYFDKRLPVSAMEAGADMA
                     AVSIHKTGGSLTQSSMLLMKCNRIKPDYVRTIINLTQTTSGSYLLLSSLDISRRNLALN
                     GEKIFEEVVGIAEYAREEINKIGGYYAFSKEINNGDDIYDFDVTKLTINTLETGLAGIE
                     VYDILRDDYGIQIELGDVANILAIISVGDTRYNIERLVSALSEIKRIHEKDKKDIFDHE
                     YIDPIVKVKPKEAFYAEKKKVLLRESEGLISGEFVMCYPPGIPILAPGELITKETIDYI
                     EYSKKKGSLVTGPEDMEIEYINVLDC"
     CDS             12294..13145
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_557"
                     /sec_met_domain="Spermine_synth (E-value: 1e-61, bitscore:
                     205.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.4e-17,
                     bitscore: 60.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYTEEHTDKVRFSIKVDEQLYSGKSDFQRIDVFKSQEFGTFF
                     TLDGLMMVTEKDEFIYHDMIVHVPMATNPNIKNVLVIGAGDGGTVRELTRYETIEKIDM
                     VEIDKLVVDVCREYLPQTANKLDDPRVSLFFEDGLKFVRSVENKYDLIIVDSTDPFGPG
                     EGLFTREFYGNCFKALKEDGILVNQHESPYYEEYARGMKRAHKRIKECFPVCRVYQAHI
                     PTYPSGHWLFGFASKKYDPLNADIEKWNDLGLKTKYYNTDLHKGCFALPNYVKEMLENV
                     DE"
     CDS             13132..13989
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_558"
                     /sec_met_domain="Arginase (E-value: 2.6e-75, bitscore:
                     250.9, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLMNRNVSTFIGCEAEYYESSIVVFGAPFDSTTSFRPGTRFASQV
                     MRGESWGLESYSPYQDLDLYDFNIFDGGEIELPFGNSEGALALIEDFSTKVVEDGKIPA
                     MIGGEHLVTLGAFKGVFKKYPDVHVIHFDAHSDLREDYLGQKLSHATVIHRVWDLVGDN
                     KIFQFGIRSGEKEEFLWAKDHVYTNKFNCDTLDYALERVKDKPVYVTIDLDVLDPSVFP
                     GTGTPEPGGIQFNELLNSILKLRGLNIVGFDINELSPQYDQTGASTAVACKVLREMLLV
                     ANNK"
     CDS             complement(14305..14568)
                     /locus_tag="ctg1_559"
                     /transl_table=11
                     /translation="LKELFVGYLIVINLVAIILMYIDKQKAKKHQWRISEDTLIGVSII
                     GGGIGALWGMHVFRHKTKHAKFTIGIPLIIAIQALLILYFIR"
     CDS             14777..18298
                     /locus_tag="ctg1_560"
                     /transl_table=11
                     /translation="MKSKKIIATLVASLVISNMGGYLVKANPNVNHKAVIIEDRQAIIE
                     TAIPQSEMTASATSEEGQDPASSAIDGNTNTMWHTKWNGSDALPQSLSVNLGSSRKVSS
                     IAITPRTSGNNGFITKYEIHAINNGVETLVAEGTWEENNLVKTVTFDSPIDAEEIKITA
                     IQGVGGFASIAELNVYEIKGEVDEIANYGNLKITKEEERVNITGDLEKFSSIEEGTIVT
                     RFNMNDTSIQSLIGLSDGNKANNYFSLYVSGGKVGYELRRQEGNGDFNVHHSAEVTFNK
                     GINTLALKIEKGIGAKIFLNGSLVKTVSDPNIKFLNAINLNSGFIGKTDRANGYNEYLF
                     RGNIDFMNIYDKPVSDNYLLRKTGETKAPLEDSLLPDDVYKTQPVDLFYPGYLESRGYR
                     IPALETTKKGTVLASIDVRNNGDHDAPNNNIDVGIRRKEVNGEWEEGKVILDYPGKSAA
                     IDTSLMSATIEENGIEKERIFLIVTHFPEGYGFPNTEGGSGYKEIDGKYYFILKDAQNN
                     EYTVREDGIVYNSEGNETDYVMKNDKTLIQNGEEVGNALLSNSPLKAVGTAHIEMIYSD
                     DDGNTWSEPEDLNPGLKKEWMKFFGTAPGKGIQIKNGEHKGRLVFPIYYTNQNNFQSSA
                     VIYSDDFGETWKLGESPIDTASVSSETVSSGTQLTECQVVEMPNGQLKLFMRNTGSYTK
                     IATSFDGGATWHDEVPEDTSLREPYCQLSVINYSGKINGKDAIIFSNPDASSRVNGSVK
                     VGLINENGTYDNGEPRYEFDWIYNKTVKPGSFAYSCLTELPDGNLGLFYEGEGAGRMAY
                     TEFDLNYLKFNASEDSPSSSVQSIEILDEDLTYNSGEEVSIKVNFNQLVSLIGDRKITL
                     DIGGVDVPLNMVNYEGKSSAIFKGTMPEGINSGSYEIKLKENNALELNTVYNKVSTLNG
                     LDNTGINIQIGELKTTVGNSTLKVNDEVQVGSTFDAILGIEGLNRDTEAYSAEYLFEYN
                     AEAFKLNEITSFSDSLFVKSKEVEPGKVRILVASLGNEIEKDSDLVKVNLTPQISSELE
                     VLGLTTALVGSGDGNTHDLELSSKEVKINEEASGEIVVNPVQNFEIPEINKKNVKLTWN
                     APITTEGLEGYVIYKDGKKLSEVPAESTEFVVSKLNRHTIYNFKVAAKYSNGELSAKES
                     KTIRTAR"
     CDS             18444..19079
                     /locus_tag="ctg1_561"
                     /transl_table=11
                     /translation="MKKKLLGMLLAGTLMVGAVGSYAWFSDKAEVNSGIKLTMGTLDVE
                     VKEHSDGWEIVDETSEIINKNSTKHFKNVRPGDSFQREFYINNTGTLKQNVTVKLNPDI
                     AKKVVATIEGQAVTFDELFNLTFDLEATPLSEEKGSEIKFMLDSVYSEDENANPSTSAV
                     NMKVNLEVDKKGMDDRFNHEGNKFVEIFDFLKDKSVPLVLVEAEQVNK"
     CDS             complement(19192..21861)
                     /locus_tag="ctg1_562"
                     /transl_table=11
                     /translation="MSAIIFMINKSIKIKGMSCAACAARIEKVLGKMDGISKANVNLAT
                     EKLNLEFDENKISFKEIEEKINKLGFSVVRNLKKESFRVSGMSCASCAARIEKVLNKLS
                     GIYNATVNFANESLQVEYDEDEISLEEIKEKVKKLGFELKGNNKSTSFKVEGMTCSACA
                     ARIEKVTSKMDGVESSNVNFANSTLNISFDKDKLSTNDIKAKVEKLGYKLLDASQEDEH
                     EKAKENETKRMKNRLIGSAIFTIPLFIISMGHMVGLHLPNIIDPMHNPLNFALIQLLLT
                     TVVIFICRDFFIHGFKNLFMRSPNMDSLIAIGSGAAYVYGLFAIYHIYIGDHSYAMQLY
                     FESAGTILTLISLGKYLETLTKGKTSDAIKKLMGLAPKTATLLVDGKEKIVSIDDVKVF
                     DLILVKPGEKLPVDGKVVEGYTSIDESMLTGESIPAEKKVGDTVFGASINKNGRIIYEA
                     TKVGKDTVISQIVKLVEDAQGSKAPIAKLADTISGYFVPIVISLAVIASLAWYFSGESK
                     TFALTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKSGEALESTQNLNTVVFD
                     KTGTITEGKPKVTDIICENISKDELLLLAASAEKGSEHPLGEAIVRDAEEKNLELKNVL
                     DFEAIPGKGIKCSIEDKRILLGNYKLMKDKNINLKNLLATSEELALKGKTPMFIAIDEK
                     IAGIIAVADTVKETSKKAIETLQKMGLEVVMLTGDNLKTAKAIAKEVGVDRVIAEVLPQ
                     EKAEKIKSLQDEGKKVAMVGDGINDAPALAIADIGMAIGSGTDIAMESADIVLMKGDIL
                     HVVGAIQLSRQTMKNIKENLFWAFGYNTLGIPVAMGVLHIFGGPLLNPMIGAFAMSFSS
                     VSVLLNALRLKKFKPNYK"
     CDS             22153..22809
                     /locus_tag="ctg1_563"
                     /transl_table=11
                     /translation="MKKLLYITVNSKPEKLSSSKTIGRAFISRFVELNPEFEIEEVDLY
                     KDFIPRLEHKHFSGRSSVVDCETASIDVKTKEEVKRIIELSEQFKNADLYVIAAPLWTL
                     SFPAPLKEYIDCVVQNKITIKVTPEEVKGLLDDKQREMVYIQSSGGEIPWLTKGIFNKG
                     LNYVEDIMKFLGIKKFHQLLVDGTGFSIEEKFKAEDKAVEKIDNVIKDIHFSNKG"
ORIGIN
        1 ctaaagatgc attaaaagtt gctttattct ttggaggatt tcaagcgctt atgcctttaa
       61 taggatgggg agctgggaga tattttgcag attatataaa agcctttgat cattggatag
      121 catttatatt attaagtttc ataggtggaa aaatgatttt tgaagcttta aaagaagatg
      181 atgaagaaaa agctgaggtt gcagtatcaa tggaagttag caaaaataaa gaaagagaat
      241 ttgataatat gaaacgcaaa gaggagctaa gtgctaaaaa tcttacagta ttagctattg
      301 caactagtat tgatgcctta gcagttgggg ttagttttgc attcttaggt atttctatag
      361 ttcaaactat aataataatt ggtattataa cttttatttt atgtttttta ggggtaataa
      421 taggtgaaaa attaggagat atatttaaaa actatgctga aatagtaggt ggagttatat
      481 taattcttat aggtataaat atattattag aacatacagg aattattgaa aagttatttt
      541 cttagtatca taattaaggt aaggatacat atataacttt atcttaggtt gaaacttaaa
      601 atcactattt tttaaacaag agaaaaaata ttacttgtaa taatacatta acaagtgata
      661 taaatatata ggtagatttt agaataataa ttttaattaa atatatttgt gttaaatatg
      721 gtttagagtt ataaacaact aaggaggtaa tttacatgta cgttgcattt ggaaacagag
      781 tgttagatag tgaggacata aaaaaagaaa tagaacttaa tactgatgcc agagttgtaa
      841 gtgatttatg taagagctca aaaagagaag atataattgc ttttaagtta agcatagata
      901 tggatatctt aagaggtctt atgaaagaga attctgatct taaagattta aatgatgaag
      961 agttatttga agattattta gatttagcag aagaggttgc tggaatgata tttgaataca
     1021 tgccagaaga tgctatatta gatataagat catataaatg ggatatgtct tacaatgatg
     1081 taaaattaat aatggtaatg gctcatgaag atcttggaat agctaaggtt aatgatgtta
     1141 tgaagagatt attaagacaa gtagattaat tttaaatggt gcaataaact ttcaaattaa
     1201 tttttataaa ataagtttta tatgaattag ataattaaaa tctataaatg ttatttgttt
     1261 ttctaacatt tatagatttt tttattgtgt ttttaataaa ggaatttatg aaatatttat
     1321 tggaaatact tttggttgta gaaaaaatat aaaatttagt ataataaaat tattaatttg
     1381 ttgtgaataa aaattaaaga ataaatgaag gttttaattc atgtaatttt tataggtacg
     1441 attagttaaa atattttagt gatttagtag gtgattaaga tgaaactttt aagtttaaat
     1501 acggaaatac taggttttga tacttcttct gaatttgcaa aagaattaaa tttaaatgaa
     1561 aaagacctag tttttacaaa cagaagaata tatgaaggaa gttttaaatc tttagattta
     1621 aaatgtaatt atgtcttaaa ggacaaatat aatttcaatg aacctaatga tgaaattata
     1681 gatgaaattt ttaaagatat aaaaaatata gactttaata gagttatagc tattggtggg
     1741 ggatcaattc tagatgtagg taaactttta gctttaaaag acgtaagtag tacaaagaaa
     1801 ctatttaaaa gagaacttcc tataataaga gataaggagc ttattatagt tcctacaact
     1861 tgtggtactg gtagtgaggt aacaaacata tctattgtgg aaataaagag tgaaaatact
     1921 aagttaggtt tagcagtaga cgaactttat gcagataagg gagttttaat tcctgaactt
     1981 tgtaaaacaa tgccttataa agcttttgtt tatagttcta ttgatgcatt aatacatagt
     2041 atagaaggat ttttatctcc aaattctact ccatacacag atttatttgc ctttaaagca
     2101 attgaaatga ttttaagtgg atataaagag ataatagaaa aaggtgaaga gtatagaaat
     2161 actataatgg ataaattttt aattgcaagc aattatgcag gaatagcctt tggaaatgca
     2221 ggagttggtg cagttcatgc cttatcttat cctttaggag gaaaatatca tgttcctcat
     2281 ggagaagcaa attatcaatt tttaatggca gtattaaatt tctacaagaa aaacaatgga
     2341 gatggaaaaa ttagcgaatt aacaaaatta ataagcagta ttataaatgc aaaggaagag
     2401 gattgttatt tagagttaga aaacttatta aataatctta ttagaagaaa aaatttaaaa
     2461 gaatatggaa tgacaattga tgaaattgaa aaattttctc aaagtgtaat gaaaaatcaa
     2521 caaagattac ttaaaaataa ttatgtatct atggaaataa aagatatgga ggaaatttat
     2581 aaatctctat attaggaggc attatgaaat tttttaggat gattttaatt gctggagaag
     2641 ttttgcttgt aattttgttg cttttaggta ttgtgtttaa agtagctgaa tgtgaaaaga
     2701 aggataaaag tttaagtaat attaaagaac aacatgttaa attggatgat gaacaacaag
     2761 aaaaattact atattgtagt attatcagat aataatttta aatagttaat gggaaggaga
     2821 ggtacttgtg gttttagtac ttacatttat tttattttta atgatatttt taataatagt
     2881 agatttcttt gctatattat ttagacttac aggggtgcca atagaaaaag ccagatttca
     2941 agttacatct cttttgacag gaacaggttt tacaacaaaa gaaagtgaga taatagttca
     3001 acatcctact agaagaaagc ttgctatttg gcttatggga tttagttatg ccagtacagc
     3061 aactattata tcttttgcag taaatataat aactagtagt gtcatagatg taggttccat
     3121 agctgtaatt gttcttttta ttatatttgt tttatttttt cataaaagtt ctttactaga
     3181 aaagtttgaa aataaaattg agaaatttat tgttcaatct aaaatttggg acaagattaa
     3241 ttcaaagcac ttaactttaa taactaatac taaaggcttt ggtgtttatg aaatatatct
     3301 ttcaaacaag gcaacactta ttggaaagag cataagagat agtgatctta aatcaaatga
     3361 aatagaagtt ttaaatatag ataaaggtga caagtttgtt aatttcccta ctcctgacta
     3421 tacttttgag gtatgtgata aggtaacagt gtatggaaat gtaaaaaata taaaagctat
     3481 gtttaagcat ataaatgaag ttaaataaca aaatgggcgt atattaaaat aactttttat
     3541 aaaacttaca aacagtattg tttgtaagtt ttatttttta tattttgata caaacccatt
     3601 tttaaaatta tttatagcct aattagattt ttaagttatt tagattttta atcattttat
     3661 ttaaaacttc atcaaaaaac ataagttctt catcttttaa atcttctagt agtaacttaa
     3721 aaaatctatt acttactttg tttaaaacat taagtgtttc attggcagag ggagatatgt
     3781 ataatctaaa tattcttttg tctttgtcat ctttttttat tgatagcatt tcttttttta
     3841 ataagctttc tatagatctt gaaattaatc ccttagaaag accagaaaat tcaactatat
     3901 cctttgcagt attatattct aaattttcct gtaagaaaac taatatttca aattcattat
     3961 gcgttaatcc caaatcattt aatgttggtg aaataaattt tttatatgtt ttttttgctt
     4021 tagtaaaaga aactaaaaaa gcatttccat taggattaag agcttttaaa tccattaacc
     4081 ttcctccttg aatagttcaa ttgtaaactt tatataaatt ataccttaaa ttggtttata
     4141 agtaaactat atatttctta tttaaatcat ataatcatta tacatatgaa aatataattt
     4201 tttaataata tttttcaaag tttaatgtag aaaagattaa tattttttaa ttaagttaat
     4261 aatataagga taaaatagta aaaaattact ataacatatt tataaattta tttaggagag
     4321 gaaaaacatt ggagtttaaa aataataaaa ttaaagatta tattttttta tcaacatata
     4381 taatactttt aatattcttt tttataaata taaaggatat tatgaacttt ctttataagt
     4441 ttttaggaat actaaagcct tttatatggg gaatagccat agcttttatt cttaatattc
     4501 cagtgaaatt aatagagaaa aacttaggaa atagtaagtt ttttaaagga atgaaaagaa
     4561 gtttttcaat aactttaaca tttcttttct ttatattggc tataacatta tttatattat
     4621 ttgtaattcc tcaattatta agtagtattt caactttaat gaatagtatt ccagaatacc
     4681 tatctcaatt tgaaaagttt ttagaggtaa atgcaataaa taattcacag tcacaagtta
     4741 tgatgcaaaa tataattaat gagttactaa atatgtggaa agaaatatta aaggtaacaa
     4801 gtcaaatagt aggaacctcc ttaggatatt tattagactt taccctagga ataacttatg
     4861 gagtaataaa tttcttttta tccttaattt tagctatata tatgctagca agtaaagaaa
     4921 tcttaataag tcaactaaaa cttataatat atgcttttgt tagtaaaaat aaggcagata
     4981 ggattataga actagggaag atgtgtaatg aaatgttttc taaattcata ttagggcagt
     5041 gcacagaggc gttagttata ggagttttat gctttatagg gatgataatt ttaaaaatgc
     5101 catatgcttt attaataagt gtagtaattg gagtaacagc attaatacct gtttttggag
     5161 cctttttagg tacaataccc tcagcattta taatactaat aatagatcct attaaggctc
     5221 tttggtttat tatatttata atagttcttc agcaattaga aggaaatcta atatatccaa
     5281 gggttgttgg aagctctata ggattatctg ccctgtgggt tatgtttgct atgatagttg
     5341 gaggaagttt atttggaata ataggaatgt taataggaat tcctatcttt ggtgtagtct
     5401 ttaaaatctt aaagagagta gctaatagga agataaatga aaagggaatt gaaagaagat
     5461 aatttaagat attcatttta aagcagttta ttataaatag gctgcttttt tattttgatt
     5521 tttttaagga ggtataataa ggaaaaatta ataaagtgat aaaattcgac aattaaactt
     5581 ggtagtttgt taaaatgttt ctattagata tagaagtttt aagtatatgt ttttctataa
     5641 aaaacaattg tgttgttatg atacacatag aaaaatggag tatttaagag gaaatataat
     5701 caaattatta agaaacttgc aataatttgt taagagtaag tttgattaca attaaaaatg
     5761 tatttataat taaaaatgtg ttaacgaaat aataagttta atgataaatt catataaatt
     5821 gataatttga atgaggtcat aattaaaaga gggggatcaa tataaaatgg cagaggcaat
     5881 taaatctact gattttgagg tagaaaaagg caatggacga ttaaagcatc cagcaggact
     5941 atacctttta ttcttcacag aaatgtggga aagatttagt tactatggaa tgagagcttt
     6001 attaatgctt tacttaacag catcatttgt gactggtgga ttaggatatg atgtacctag
     6061 tgcagctaga atatatggag cttatacttt tttagtttac tttacaccaa taattggtgg
     6121 agaaatagca gataagtttt taggacagaa aaaatcaatt atgcttgggg cagcagtaat
     6181 gattttaggt aacttaactt tatttggatg gcaaactaga tgggctttat acttaggatt
     6241 agggttcata atagtaggaa atgctttctt taaaccaaat atatcaacaa tagttggtca
     6301 attatatgaa gatggtgaca agagaaaaga ttcagctttc acaatattct acatgggaat
     6361 aaacttagga tctttaatag caccaataat atgtggatta ttagcagaaa acttttttgc
     6421 tacaaaatca ggagaagtaa tacttcacta tggatttaga tacggattct tagcagcagg
     6481 tataggtata atattaggag aaattatctt tataacttta tctccaaaat acttagcaca
     6541 tgttggtgaa attaaaagag aaaaaaataa aaaagacgtt gcaaaagaaa agaaaccttt
     6601 aactaagcaa gagaagaaga gagttgcagt tatattaata cttgcatcat tcgttgtatt
     6661 cttctgggca ggatttgaac aagcaggtac tactttaaca ttatttgctg aaaatgcaac
     6721 taatagaagt ttatttggat ggacagtacc agtagcattc ttccaatcta taaacccatt
     6781 atttatacta atattagcac cattattctc aaaattatgg tttacacttg ctaatagtaa
     6841 aagaggggat ttatcaatcc caactaagat ggctatgggt atgatagttt taggatgtgg
     6901 attcttatta atggttttcg caactatgtc attaggtgga aatgttgaaa atccagcagt
     6961 taaagctagt atgttctggt tagtaggaac ttacttattt aacacaatgg gagaactttg
     7021 tttatcacca ataggacttt caatggtaag ttcattagca ccagctaaat acgcttcatt
     7081 attaatgggt gtatggcttg ctagtaacgg agtagcaaac tacttatcag gattcatagc
     7141 atcatttgtt gaaaaactag gagctttaga actatttggt tcaatagctg gagtgagtat
     7201 agtattaggt ttagtactat tactattaag caaaaagatt acagctatga tggaataaaa
     7261 tgatattaaa attaaatctc tttaagaaga tttgagtaat taaattagga tatttaagtt
     7321 ttatataaga aaagacacat taataaaata atgtgtcttt tttgtatttt aaaaattttt
     7381 attttaaatt tattttagtt aatttaagtt aagtattttt taaactctaa aatattcttc
     7441 atctaagtat aaaagcattt cttcagttat aggaactgac aatcctgcat agtctgaaaa
     7501 tctttggatc tcatcttctt tttcttcttt ttttagctcg tgatgatgtt taattttttt
     7561 gccagctttc ttttcaaggt ctttccactc tttataaact tttactaaat cttcttttaa
     7621 cttattatcg ctcatgaaaa acatctcctt aaataaatgt attattataa tattcttcta
     7681 attcaagtat ttctttttct gtcaatggtg tatcaatttt agcgaattca gaaaatttct
     7741 ttgttataag ttttatttgc tctttttcta actttttaaa atcatgattt aattttaatt
     7801 tttcaaaaaa gcttttttca gaaactctcc atttactata gagatctaat aactccttct
     7861 ttattttttc ctctcccata aaattcaact ccttataaat tttataaata tattatataa
     7921 taaaaatata tattttaaaa tattgtaaat aaagaaagat ttttgtttat aaaaagtata
     7981 aaatttaatt tagtaaaaaa aataatttta agaaaaaaat ttgatttaaa agatgttttt
     8041 atataagtaa ttacttatat tatatataaa gaaataattg tttactaatg gaatttagag
     8101 gcataaaatt ttagtgaggt gatataaaat gaatacatta aatgatattt tatcaaaaga
     8161 aattgaagaa tttagagaaa aaggacataa gtttttaaat aaagaaatga ctgttggtga
     8221 atttaaaaag gcatcaggag gcatgggagt ttatgcgcac cgtggaggaa aagaattcat
     8281 ggtgagatta agagttccat caggagttgc tggattaagt ttattagaag aagcatataa
     8341 ttgggctaaa aaatataact tagaaaaaat acatttaaca actcgtgaag caatacaatt
     8401 acatggaata tcaatagatg ctgtatgcga cataatgcaa gaagggttaa ctaaaggaat
     8461 atacactaga ggtggtggtg gaaacttccc aagaaacgta gccttaaatc ctttatcagg
     8521 agttcaaata ggagaaactt ttgatgtaac tccttatgca ctagcatcta atgcacatta
     8581 tatgagtaaa atatatactt ataatttacc aagaaaaatt aaaactgcat tttcaaatac
     8641 agaggaggat tcagctcatt gcacagttac agacttagga tttttagctg tggagaataa
     8701 cggtaagaga gcctttaaac tttacatagg tggaggatta ggaagaaatc caagaacatc
     8761 tgttgaattt gatgagttaa tagatgaaaa ggacgtatta tattgtcttg aagctatgac
     8821 taatttattt gtagctgaag gagattataa aaatcacgga aaagctcgta taagatatat
     8881 tgttgagaga atgggcgaag aagagtttaa aaattgcttt agaaaacact tagaagaagt
     8941 gaaagctaaa ggtggattag accttaaggt tgaagatata aaatatagta aaaaaggtga
     9001 aaaaactaat ataaaacatg aaagattaat acctcaaaaa caagaaggat tatatactgt
     9061 tttattccac cctgttggag gacaattaag cttagatgta ttaaaagaat taatagaaaa
     9121 aatagagaaa atagaagaag tagaagtaag attaggtatg gatgaaaatc tatatgttag
     9181 aaatttaaat ggaaaagaag ctgaagctat cttagacttt actcaaggta aaggaggaga
     9241 gactttagct gaaagaagtg tttcttgtat aggtacacca atatgtcaaa tgggagtact
     9301 agaaagccaa aaaactttaa gagagtttgt agaattatta aaagaaaatt caattaagga
     9361 aggaatatta cccagagttc gtttctcagg atgtccaaat tcttgcggta tgcatgaaat
     9421 aggagatata ggattcgctg gtaaaaagaa aaaagttggt gatgttttat caaatgtatt
     9481 tgaattacat tttggtggaa agttaggcat aggtgaaact cgtttaggag attactatgg
     9541 agatatactt caagacaagg ttccagaatt cttaattaag gttgcaaagg ctgtagaagc
     9601 taaaaattca acttttgaag agtggattaa ggataatagt gaagaattta aagctatagt
     9661 tgaagaatat aatgtatagc tgttaacaaa atatttacaa aatccaaaaa aacttaataa
     9721 ataagttttt ttggattttt tgatttttac ttaaaattcc tttgaatagg catatttaaa
     9781 tactttttta gtttatttta ttaaatatta ggtttagtaa tactaagtat tttacttagt
     9841 ttttgttacc gaaatattaa cgatgacctt tgaagatagc ttgaaataag ggttagaaag
     9901 aatttgctat agaaaaaaat aaaatggtga tatataataa attcaaaatt tatatttatg
     9961 cagttaaata agttgtttaa agaaaggatt gatgttaggg ttgaaagaaa agatatgcct
    10021 ttatggtttt aataatctta ctaagacact aagttttaat atttatgata tttgttatgc
    10081 gaaaacagag agagaaaagg aagactatat aaaatatata gacgagcagt ataattctga
    10141 acgtcttaca aagattcttt gtgatgttac agaaatgata ggagctcatg tcctaaatat
    10201 ttcaaaacaa gattatgaac ctcagggagc tagtgtaaat gttcttataa cagaggaggc
    10261 attaccagta gcactaattg acccatcatg taataaagga gaaatttcat atttggagct
    10321 tagggatagt gtagttggac atttagataa aagtcatctt acagttcata cttatccaga
    10381 gtttcatcca aataacgata taatttcttt tagagttgat atagatgtat ctacttgtgg
    10441 aaaaatatct ccattaaatg ctctagatta cttaatcgga agttttgatt cagatgtaat
    10501 aactattgat tatagagtta gaggatttac tagagatgtt gatggtagaa aatgctacat
    10561 agaccatgat ataaaatcta ttcaagatta tatagatgga gagaccctaa aaaaatacga
    10621 tgctatggat gttaatgttt atcaatctaa catattccat acaaagatga tgcttaagga
    10681 tatagtttta aataactatt tatttaattc tgatccatat gaattatctc caaatgatag
    10741 aagagaaata agagatagaa tatcaaaaga gatgattgaa atatacggtg gtgtaaatat
    10801 ttattaagaa aaggagggat ttctgtgaaa agactttctc aagaaaatgc tcctatttat
    10861 gaagcattaa aatggtacaa aaatcaaaga attgttcctt ttgatgtacc aggtcataaa
    10921 caaggaagag gaaatacaga attaagagaa tttttaggtg aagattgtgt ttcagtagat
    10981 gtaaattcaa tgaaaccctt agataatctt tgtcatccaa cttctgtaat aaaggatgca
    11041 gaggaattag cagctgaggc ttttggtgct gataaggcgt ttttcatggt taatggaact
    11101 acatcagctg tacaagccat gataatgagt gtttgtaaag acggagataa gattataatg
    11161 cctaggaatg tgcataggtc tgccataaat tctttaataa taacaggggt aactcctgtg
    11221 tatataaatc caggaattca tggtagactt ggaatttctc tagggatggc aatggaagat
    11281 ataaaaaaag ccattaagga aaatccagat gctaaggcta tttttgttaa taacccaaca
    11341 tactatggaa tttgctctaa tttaagagag atagttaagt tagctcatga aaataatatg
    11401 tatgtcttag ttgatgaagc tcatggaact catttttatt ttgataaaag acttccagta
    11461 tcagctatgg aggcaggggc agatatggca gcagttagca tacataaaac aggaggctca
    11521 ttaactcaga gttctatgct gcttatgaag tgtaatagaa ttaagccaga ttatgtgaga
    11581 acaataataa acttaacaca aacaactagt ggttcttatt tacttttatc ttctttagat
    11641 atttctagaa gaaatttagc cttaaatgga gaaaaaatat ttgaagaggt tgttggaata
    11701 gctgaatatg caagagaaga aataaataag ataggtggtt attacgcttt ctcaaaagaa
    11761 ataaataatg gtgatgatat ttatgatttt gatgtaacta agcttactat aaacacttta
    11821 gaaactggac ttgctggaat agaagtttat gacatattaa gagatgatta tggaattcaa
    11881 atagagcttg gagatgtggc taatattctt gccataatat cagttggaga tactagatat
    11941 aacattgaga gattagtttc agctttaagt gagattaaga gaattcatga aaaagataaa
    12001 aaagatattt ttgaccacga atatatagat cctatagtta aggttaagcc gaaagaggct
    12061 ttttatgctg aaaagaagaa ggttctttta agagaaagtg aaggattaat ttctggagaa
    12121 tttgtaatgt gttatccacc aggaattcca atacttgccc caggagagct tataactaag
    12181 gagactatag attatattga gtattctaag aaaaagggaa gtttagttac aggccctgaa
    12241 gatatggaaa ttgaatatat aaatgtttta gattgttagg aggaatttta attatggaat
    12301 tatggtacac agaagaacat acagacaagg tacgtttttc aatcaaagta gatgaacaac
    12361 tttatagtgg aaagagtgat ttccaaagaa tagatgtttt taaatctcaa gagtttggaa
    12421 ctttcttcac attagatgga cttatgatgg taacagaaaa ggatgaattt atttatcatg
    12481 acatgatagt tcatgttcca atggctacaa atcctaatat aaaaaatgta ctagttatag
    12541 gagctggaga tggtggaact gtaagagaac ttacaagata tgaaactata gaaaaaatag
    12601 acatggttga aattgataag ttagttgttg atgtttgtag agaatattta cctcaaacag
    12661 ctaataaatt agatgatcct agagtaagtt tattctttga agatggatta aaatttgtac
    12721 gttcagttga aaataaatat gacttaataa tagttgattc aacagatcca tttggacctg
    12781 gagaaggttt attcacaaga gaattttatg gaaattgctt taaggcatta aaggaagatg
    12841 gaatacttgt aaatcaacat gaaagcccat actatgaaga gtatgcaagg ggaatgaaga
    12901 gagctcataa gagaataaaa gaatgtttcc cagtatgtag agtttatcaa gctcatatac
    12961 caacttatcc atcaggacat tggctatttg gctttgcatc aaaaaaatat gatccattaa
    13021 atgctgatat agaaaagtgg aatgatttag gattaaaaac taaatattat aacactgatt
    13081 tgcataaagg atgttttgca ttacctaatt atgttaagga gatgctagag aatgttgatg
    13141 aatagaaatg taagcacttt tataggatgt gaagctgaat attatgaatc aagcatagtt
    13201 gtatttggag ctccttttga ttcaacaact tcttttagac caggtactag gtttgcaagc
    13261 caagtgatga gaggagaatc ttggggatta gaaagctata gtccatatca agatttagat
    13321 ctttatgatt ttaatatttt cgatggcgga gaaatagagc ttcctttcgg aaattcagag
    13381 ggagcattag ctttaataga ggatttttca actaaggttg ttgaagatgg gaaaatacca
    13441 gctatgatag gtggagagca tttagtaact ttaggggcat ttaaaggagt atttaaaaaa
    13501 tatcctgatg ttcatgtaat tcactttgat gctcattcag atttaagaga agattattta
    13561 ggtcaaaaac tatctcatgc tactgttata catagagttt gggatttagt aggagataat
    13621 aaaatattcc aatttggaat acgttctggt gaaaaagaag aatttttatg ggcaaaggat
    13681 cacgtttata caaataagtt taattgtgat actttagatt atgccttaga aagggttaaa
    13741 gataaacctg tttatgtaac aatagactta gatgttttag acccatctgt attcccaggt
    13801 acaggaacac cagaaccagg tggaattcag tttaatgagc ttctaaattc aatattaaaa
    13861 cttagagggt taaatattgt gggatttgat attaatgaat tatcaccaca gtatgaccaa
    13921 acaggagcat caacggctgt agcttgtaaa gttttaagag agatgttatt agtagcaaat
    13981 aacaaataga atgattttaa agatagatta gccttagata aatttaggat atggatttaa
    14041 gaactagttt taattttaac tagttcttaa tcaattcagt taagggtata tttagagatt
    14101 tttaaagtta attacaattt atgcaaaata tactttaagt taaatttaat ttagaatttt
    14161 tagagattta aatataaaaa atagaactgt atcaaaagct aataaaaaat ttcttaaatt
    14221 aatgagagag agtatttatt aactctttca aaaatagttt tagaattttt taaaggttaa
    14281 tttgatacag ttctttttgt gtatttatct aataaagtaa agaattaaaa gtgcttgaat
    14341 tgctattatt aaaggaatac ctatagtaaa ttttgcatgt tttgttttat gacgaaagac
    14401 atgcattccc cataatgctc caattcctcc tcctattata gaaacgccta ttaaggtatc
    14461 ttcacttatt ctccattgat gttttttagc tttttgttta tctatataca ttagaattat
    14521 tgccactaaa tttattacaa tcaaataacc tacaaaaagt tctttcaata attacccctc
    14581 ctaatttatt tcattagtat ttattatatg gttcttaact taattataac ttatttctag
    14641 ggaaagttat tattaattag tagataaata taaaatttgg gtagtataaa ttgtatttca
    14701 tacaatttta gtaatattaa agcttattta aacgtataca taatataagg tcattttatt
    14761 ttaaggggga gagctaatga aaagtaaaaa aattatagct acacttgttg caagtttagt
    14821 tatttctaat atgggaggat atttagtaaa ggctaatcct aatgtaaatc ataaggcagt
    14881 tattatagaa gatagacaag ctattattga aactgctatt ccacaatcag aaatgacagc
    14941 tagtgcaact tcagaagagg gccaagatcc agcttcaagt gctattgatg gaaatacaaa
    15001 cactatgtgg catacaaaat ggaatgggag tgatgcgctt ccgcagagtt tatcagtaaa
    15061 cttaggaagt tctagaaaag ttagttctat agctattaca ccaagaacaa gtggaaacaa
    15121 tggatttata actaagtatg aaattcatgc tattaataat ggagtagaaa ctttagttgc
    15181 agaaggaacc tgggaagaaa ataatttagt taaaactgta acttttgatt ctcctattga
    15241 tgcagaagag ataaaaataa ctgcaattca aggtgttggt ggatttgctt caatagcaga
    15301 gttaaatgtt tatgaaatca aaggcgaagt agatgaaatt gctaactatg gaaacttaaa
    15361 aataactaag gaggaagaaa gggtaaatat aactggtgat ttagaaaaat tctcctcaat
    15421 agaagaagga actatagtca ctagatttaa tatgaatgat acctcaattc aaagtttaat
    15481 tggtttaagt gatggaaata aagcaaataa ctatttttca ctttatgtaa gtggaggaaa
    15541 agtaggatat gagcttagaa gacaagaagg aaatggagat tttaatgtac atcacagtgc
    15601 agaggttact ttcaataaag gaataaatac tttagcttta aaaatagaaa agggaatagg
    15661 agctaagata tttttaaatg gttctctggt taaaactgta tcagatccaa atattaaatt
    15721 tttaaatgca ataaatctta atagtggatt tattggtaaa actgatagag caaatgggta
    15781 taatgagtac ttatttagag gaaatataga ttttatgaat atttatgata aaccagtaag
    15841 tgataattat ttgttaagaa aaacaggaga aactaaagca ccattagaag atagtttatt
    15901 gccagatgat gtttataaaa cacaaccagt agacttattc tatcctggat atttagaatc
    15961 aagaggatat agaattcctg ctttagaaac aactaaaaaa ggaacagttt tagcttctat
    16021 agatgttaga aataacggag atcatgatgc tcctaataat aacatagatg taggtataag
    16081 aagaaaagaa gtaaatgggg aatgggaaga aggaaaagta atattagatt atccaggtaa
    16141 atcagcagct atagatactt ctcttatgtc agctactata gaagagaatg gaattgaaaa
    16201 agagagaata tttcttatag taactcattt cccagaaggt tatggattcc ctaatacaga
    16261 gggtggaagt ggatataaag aaattgatgg aaaatattat tttatattaa aagatgctca
    16321 aaataatgaa tatacagtta gagaagatgg aattgtttat aattcagaag gaaatgaaac
    16381 tgattatgta atgaaaaatg ataagaccct tattcaaaat ggagaagaag tcggaaatgc
    16441 tttactaagt aattctccac ttaaggcagt tggaactgct catattgaaa tgatttatag
    16501 tgatgatgat ggtaacacat ggagtgaacc agaggattta aatccaggac ttaagaagga
    16561 gtggatgaaa ttctttggaa ctgcaccagg aaagggaatt caaataaaaa atggagagca
    16621 taaaggtcga ttagtattcc caatatacta tactaatcaa aataatttcc aatcaagtgc
    16681 tgtaatttat agtgatgact ttggtgaaac ttggaagtta ggagaatctc caatagatac
    16741 agcttctgta agctctgaaa cagtttcttc aggaactcag ttaacagagt gccaagtagt
    16801 tgaaatgcca aatggacaac taaaattatt tatgagaaat actggttcat atacaaagat
    16861 tgcaactagt tttgatggag gagcaacatg gcatgatgaa gttccagaag atacttcttt
    16921 aagagagcct tattgtcaat taagtgttat aaattatagt ggaaaaataa atggtaaaga
    16981 tgcaattata ttctcaaacc cagacgcaag tagtagagta aatggaagtg ttaaggttgg
    17041 cttaataaat gagaatggaa cttatgacaa tggagaacca agatatgaat ttgattggat
    17101 ttataataag acagttaagc caggttcatt tgcttattct tgtttaacag agttaccaga
    17161 tggaaaccta ggattattct acgagggtga aggggcaggc agaatggcat atactgaatt
    17221 tgatttaaat taccttaagt ttaatgcttc tgaagattca ccatcatctt cagttcaatc
    17281 aattgaaatt ttagatgaag atttaactta taattctgga gaggaagttt caataaaagt
    17341 aaacttcaat caattagtta gtctaatagg agatagaaaa ataactttag atataggtgg
    17401 agtagacgta ccactaaata tggttaatta tgaaggaaaa agctcagcta tatttaaagg
    17461 aactatgcca gaaggaatta attcgggaag ttatgaaata aagcttaagg aaaataatgc
    17521 tttagaactt aatactgttt ataataaagt ttcaactttg aatggattag ataatacagg
    17581 aattaatata cagattggtg aattaaaaac aactgtggga aattcaaccc taaaggttaa
    17641 tgatgaagtt caagttggct caacatttga tgctatatta ggaattgaag gattaaatag
    17701 agatacagaa gcttattcag cagaatattt atttgagtat aatgcagaag catttaaatt
    17761 aaatgaaatt acttcattta gtgattcttt atttgtaaag agtaaagaag ttgaaccagg
    17821 aaaagttaga atattagtag catctttagg aaatgaaata gaaaaagatt cagatctagt
    17881 aaaagttaac ttaactccac agatttcttc tgaattagaa gttttaggat taacaacagc
    17941 tttagtagga tctggagatg gaaatactca tgacttagaa ctttcaagta aggaagttaa
    18001 aattaatgaa gaagcttcag gagagatagt agtaaatcca gtacaaaatt ttgaaattcc
    18061 agaaataaac aagaaaaatg ttaaattaac atggaatgct ccaataacaa ctgaggggtt
    18121 agagggatat gtaatatata aagatggaaa gaaattatca gaagttccag ctgaatctac
    18181 agagtttgtg gtttcaaaat taaatagaca tactatttac aattttaaag ttgcagctaa
    18241 atattcaaat ggagaacttt cagctaaaga aagtaagact ataagaactg ctaggtaatg
    18301 aataaattta aaattaaatg taaataagta aaaaataagt aatattatgt aatgtaaacg
    18361 aatataaata tttatgtaga ttattaaagt aatcatacat tttgtatata taaaaaattt
    18421 gaaatgtttg ggggagaaat tttatgaaga aaaaattatt aggtatgtta ttagccggaa
    18481 cattaatggt aggagcagtt ggatcatatg cttggttctc agataaagca gaagttaatt
    18541 caggaattaa attaacaatg gggactttag atgttgaagt gaaggaacat agtgatggat
    18601 gggagattgt tgatgaaaca tcagaaataa taaataaaaa ttcaactaaa cactttaaaa
    18661 atgttagacc aggagatagt ttccaaagag agttttatat caataatact ggtacattaa
    18721 agcaaaatgt aacagttaaa ttaaatcctg atatagctaa aaaagtagtt gctacaattg
    18781 aaggtcaagc agttactttt gatgaattat tcaatttaac ttttgattta gaagcaactc
    18841 cattaagtga ggaaaaagga tcagagatta agtttatgtt agattcagtt tacagtgaag
    18901 atgaaaatgc taatccatca actagtgctg taaatatgaa agttaactta gaagtagata
    18961 aaaagggaat ggatgatagg tttaaccatg agggaaataa gttcgttgaa atatttgact
    19021 tcttaaaaga taaatcagtt ccactagtac ttgttgaagc agaacaagtt aataaataat
    19081 attaatttaa aataaaaaac agagtccatt agactctgtt ttttattttg tgattaagga
    19141 ttttaaaggt ttataattta aatttaaata taatatattt aaatttaaag cttatttata
    19201 gtttggtttg aattttttta gtcttaaggc atttaataat actgatactg aactaaagct
    19261 catggcaaag gcacctatca ttggattaag taatgggcct ccaaatatat gaagaactcc
    19321 cattgctact ggaataccta aagtgttgta tccaaaggcc cagaataagt tttcctttat
    19381 atttttcatt gtttgcctgc ttaattgaat agcaccaaca acatgtaata tatcgccttt
    19441 cattagaact atatcagcag actccatagc tatatcagta cctgaaccta tagccattcc
    19501 aatgtcagca atagctaaag caggagcatc atttattcca tcaccaacca tagcgacttt
    19561 tttgccttca tcttgaagag atttaatttt ttctgctttt tcttgaggaa gaacctcagc
    19621 gataactcta tctacaccta cttcttttgc aatagcctta gctgttttta aattatctcc
    19681 tgttaacatt actacttcaa gtcccatttt ttgtagagtt tctatagctt ttttacttgt
    19741 ttctttaaca gtatcagcaa cggcgattat accagctatt ttttcatcaa tagcaataaa
    19801 cataggagtt tttcccttta aagctagttc ttcagaagtc gctaataaat ttttaagatt
    19861 tatattttta tctttcataa gtttatagtt acctaataaa attcttttat cttcaataga
    19921 acatttaatt cctttaccag gtattgcttc aaaatctaaa acatttttta gttcaagatt
    19981 tttttcttca gcatctctaa caatagcttc tccaagagga tgttctgaac ctttttctgc
    20041 tgaggcagct aataaaagga gttcatcttt tgaaatattt tcacaaataa tatctgtaac
    20101 cttaggtttc ccttcagtta tagttcctgt tttatcaaat acgacagtat ttaaattttg
    20161 tgtactttct aaagcttcac cacttttaat aagtattcca ttttcagctc ctttacctgt
    20221 accaaccata atagctgttg gggtagctaa acctaaagca catggacaag caattactaa
    20281 tacagatata aatattgtaa gtgcaaaagt tttactttca ccagagaaat accaagctaa
    20341 acttgcaatt actgctaaag atattactat aggtacaaaa taacctgaaa tagtatcagc
    20401 taatttggca attggagctt ttgatccttg agcatcttct actaacttaa ctatttgaga
    20461 gattacagta tccttaccaa cctttgtagc ttcataaatt attcttccat ttttatttat
    20521 actagctcca aagactgtat ctcctacttt tttttcagca ggaatacttt ctccagttag
    20581 catactttca tcaattgatg tatatccttc taccacctta ccgtctacag gtaatttctc
    20641 acctggctta acaagtatta aatcaaaaac tttaacatca tcaatagata caattttttc
    20701 tttgccatct acaagtagag tagctgtttt aggggctaat cccataagtt tttttattgc
    20761 atcagaagtt ttacctttag ttaaagtttc taagtattta cctaaactta ttaatgtaag
    20821 tattgttcca gcagattcaa aatataactg catagcatag ctatggtcac caatataaat
    20881 gtggtatatt gcaaataatc cataaacata tgcagcacca gatcctatag ctattaagga
    20941 atccatatta ggacttctca taaataaatt cttaaaacca tgtatgaaga aatctctaca
    21001 tatgaagata actacagttg taagaagcaa ttgaataagt gcaaagttta agggattatg
    21061 catcggatct attatattag gtaaatgaag gccaaccata tgtcccattg atattatgaa
    21121 taatggaatt gtgaatattg ctgagccaat aagtctattt ttcattcttt tagtttcatt
    21181 ctcttttgct ttttcatgtt catcttcttg agatgcatct aaaagtttat atcctaattt
    21241 ttctaccttt gcttttatat cattagtaga aagtttatct ttatcgaaag aaatattaag
    21301 agtggaattt gcgaagttaa cattagaact ttcaacacca tccattttac ttgttacctt
    21361 ttcaattcta gctgcacagg ctgaacaagt cattccttct accttaaagg aagtagactt
    21421 attatttcct tttagttcaa agcctagttt ctttactttt tctttaattt cttctaagga
    21481 aatttcatct tcatcatatt caacttgaag gctttcatta gcaaagttaa cagtagcatt
    21541 atatattcca gataatttat ttaaaacttt ctcaattcta gcagcacaag aagcacaact
    21601 cattccagaa actctgaaag attctttctt taagtttcta actactgaga aacctagctt
    21661 atttattttt tcttctattt ctttaaagga tattttattt tcatcaaact ctaaatttaa
    21721 tttttcagtt gccaaattaa cattagcttt tgatatgcca tccattttac ctagaacttt
    21781 ttcgattcta gcagcacaag cggcacaact catacctttt attttaattg atttatttat
    21841 cataaaaatt atagctgaca tattcccttg ttataaagaa aggaataaca gttttcctcc
    21901 ttttaaattt ttacctcccc tagggggtgg ttgtgattca aatatactct ttgatttttc
    21961 ttttgtcaat aataaagtga taagtattat caatgaaatt taagatttat ggtaagtatt
    22021 tttaataata taaacttatt ttggctaaaa aataaaaact tatttaaaat tagataatta
    22081 ttaataaaaa actaaaaaaa tcacaagata agaaaaagaa gttaatttag aaaaattaaa
    22141 tgaggtgagt atatgaaaaa gttactttat attacagtaa actcaaagcc agagaagctt
    22201 tcatcaagta agactattgg aagagctttt ataagtagat ttgtggaact aaatccagag
    22261 tttgaaatag aggaagtgga cttatacaaa gattttattc ctagattaga gcataagcat
    22321 ttttcaggaa gaagttctgt ggtggattgt gagactgcta gtatagatgt aaagacaaag
    22381 gaagaagtaa aaagaataat agaattaagt gagcaattta aaaatgcaga tttatacgta
    22441 atagcagccc ctttatggac actatctttt ccagcaccat taaaagaata catagattgt
    22501 gttgtacaaa acaaaataac aattaaagta acaccagaag aggttaaggg cttgttagat
    22561 gataaacaaa gagaaatggt gtatatacaa tcttcagggg gagaaattcc ttggcttact
    22621 aaagggatat ttaataaagg cttaaactat gttgaagata taatgaaatt cttaggaata
    22681 aaaaaattcc atcaattatt agtggatgga acaggtttta gcatagaaga aaaatttaag
    22741 gctgaagata aggctgttga aaaaatagat aatgtaataa aagacataca ttttagtaat
    22801 aaaggttaaa ataaaagcat tttatttggt taagaaaatt tcatataaaa attaaatttg
    22861 gttatattta aagattgatt tttaggttca taaatatttt aaagagaatt tatcaaagag
    22921 atttattaat aaaacttact agtaaataac atattaattg taagttttat tcatgatctt
    22981 tgataaattc ttttacttta aatatgagaa aaagtatttt aaagacaagg tttctaaatt
    23041 caaaagagaa cgaatgtttg catttcttac ttttatatgt tatacttaac tctcagcttg
    23101 tgggtttaaa tgctgaaatt agaatataga aataaattat ttttataata aaataaagtt
    23161 tagagtttat tctcaggttt aaaaaggtat agaagagaga taaaatattt aaattacaat
    23221 aacggtaaat tgtaattcac ttcgtaaaga ggattttcac ttcaataggt acaaaattat
    23281 tttatactaa tgttttaaaa tttctaaaaa catgataaat ggtataaaaa cataacacct
    23341 aaaatattct taataaatcc agtaaaaaat ttaaaagtat gttattaatt cagtatagtt
    23401 ttacattata ggactattta tttaagattt ataaaaaggt actgcgtgaa aaattaataa
    23461 tatgtatttt catatattat agctaattaa agttgattta gaatgatatt tgattagttt
    23521 aatttttgtt gaaaaaaata gaatatattc atactagttg ttaactcaaa agagaaacta
    23581 gatgattttt aatacttaca attaaacctg tgaattaaag gaaaaaaata aaaattttga
    23641 tatataaata ttaaattatg tctataattt aagtgaaagt tgaattctct atatagggag
    23701 aattcattta aaatgtaaat taaaaggagg atacaaattt gttaatatat aatatttgta
    23761 atgaatttag taaaagtaaa aagaataaaa gaagaactag tacagatgta aagaatattt
    23821 taaatgaggc aaaaaataaa tagattttat tatgtagagc actgttttat ataatggtgt
    23881 ttttttatta ttttaaatac tattttaaaa gcttatgaag atagtaatat agccattaat
    23941 agagactaac atagtattta gtatttaata aattatatga aataaattt
//
