LOCUS       NZ_CP076401.1          25856 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP076401.1 Clostridioides difficile strain S-0253 chromosome,
            complete genome.
ACCESSION   NZ_CP076401
VERSION     NZ_CP076401.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:19:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3574277
            Orig. end    :: 3600133
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25856
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3584277:3590133]"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15856
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
     cand_cluster    1..25856
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /kind="single"
                     /product="proline2aminovalerate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25856
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proline2aminovalerate"
                     /region_number="15"
                     /rules="(Proline_reductase and (Pro_racemase or GRDB) and
                     not ACP_syn_III_C)"
                     /tool="gutsmash"
     CDS             complement(304..1980)
                     /locus_tag="ctg1_3097"
                     /transl_table=11
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITGP
                     TGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGNTGATGANG
                     ITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGATGAT
                     GANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIGATGA
                     TGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGLVGPTG
                     ATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGATGANGVA
                     GPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTGPTGANGA
                     TGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFNSSFINGTN
                     ITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSD
                     VSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     CDS             complement(2358..2897)
                     /locus_tag="ctg1_3098"
                     /transl_table=11
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLKG
                     SFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDITD
                     SALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFDFGD
                     YYRNVPYIFNVTDEDR"
     CDS             complement(3225..4532)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3099"
                     /sec_met_domain="SDH_alpha (E-value: 1.3e-54, bitscore:
                     183.4, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIVE
                     NRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIAED
                     YMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNEPKV
                     SASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQKTGIG
                     VGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTAILPIV
                     AYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGISWLMNGT
                     EKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVPPLNGIVG
                     SSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     CDS             complement(4578..4670)
                     /locus_tag="ctg1_3100"
                     /transl_table=11
                     /translation="MVIEYKTKNIKRYKKYGMYFAINIDKKLFN"
     CDS             complement(4957..6723)
                     /locus_tag="ctg1_3101"
                     /transl_table=11
                     /translation="MIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGVYIDK
                     IGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICDGDSHG
                     VIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKLETLLNN
                     MDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFKKDKSCSF
                     FYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIKLENIIGES
                     VAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIAVNCAAIPDN
                     LLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSKLLRVLQEKEL
                     NKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLPSLRERKEDIPL
                     IIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYSVNMSSSSIITMN
                     VIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDKELTAKALGISRAT
                     LYRKIEKYNIIS"
     CDS             complement(6944..7513)
                     /locus_tag="ctg1_3102"
                     /transl_table=11
                     /translation="VKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIGN
                     LGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVDQF
                     NVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHEVFN
                     IFSRLNFDGMIKESNKLKYIYVGKRR"
     CDS             complement(7697..8332)
                     /locus_tag="ctg1_3103"
                     /transl_table=11
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSDS
                     FDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDEEN
                     KDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFAKNL
                     KVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     CDS             complement(9000..9881)
                     /locus_tag="ctg1_3104"
                     /transl_table=11
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVTG
                     FITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIPVD
                     GVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLPGGG
                     NELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGSCALL
                     MPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIAYTSAT
                     MIMAANKNKKTA"
     CDS             complement(10001..11008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Pro_racemase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3105"
                     /sec_met_domain="Pro_racemase (E-value: 5.7e-131, bitscore:
                     434.1, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEENL
                     DYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAAIE
                     TGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPGVGT
                     VKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLAHIKT
                     VDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGEKFVYE
                     SILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFILK"
     CDS             complement(11028..11501)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3106"
                     /sec_met_domain="Proline_reductase (E-value: 2e-19,
                     bitscore: 67.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNEW
                     KTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGADGL
                     VITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK"
     CDS             complement(11528..11995)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3107"
                     /sec_met_domain="Proline_reductase (E-value: 3.2e-31,
                     bitscore: 106.4, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNEN
                     KTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQAK
                     FVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     CDS             complement(12010..12768)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3108"
                     /sec_met_domain="Proline_reductase (E-value: 1.9e-66,
                     bitscore: 222.2, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKER
                     EELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGADED
                     GNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRACDD
                     FIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKEPSGF
                     EGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     CDS             complement(12848..13093)
                     /locus_tag="ctg1_3109"
                     /transl_table=11
                     /translation="VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPH
                     NIEMQTHILRDTLEQLVAIPSAGKIVPLPYEYKAHV"
     CDS             complement(13121..13573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3110"
                     /sec_met_domain="GRDB (E-value: 5.4e-17, bitscore: 59.8,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVHL
                     KSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAEGF
                     IKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAG"
     CDS             complement(13611..13895)
                     /locus_tag="ctg1_3111"
                     /transl_table=11
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLIT
                     DYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     CDS             complement(13976..15856)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3112"
                     /sec_met_domain="Proline_reductase (E-value: 7.4e-212,
                     bitscore: 700.4, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLEDS
                     GLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAPVS
                     EAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAAEVA
                     PKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVVDMKL
                     EIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQIGEFGS
                     SEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQEIREAL
                     KKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLGAQPNVDL
                     GNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDLVGVVFVGS
                     PQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMRGIPVVGVSF
                     SAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAMLKNAIEGVEVK
                     APERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKDEN"
     CDS             complement(16285..18045)
                     /locus_tag="ctg1_3113"
                     /transl_table=11
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMVI
                     DSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILKNI
                     GILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVILWN
                     KFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVHANPI
                     FYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGKSYKLE
                     KSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPNELFESE
                     FFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEKEIRRVGG
                     DTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKEDIGLLVHSF
                     LEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSKIDVDDVPSY
                     MMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILNIPRTTLYYKI
                     DQYKIDVSKI"
     CDS             complement(18452..20626)
                     /locus_tag="ctg1_3114"
                     /transl_table=11
                     /translation="LKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGEE
                     QSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPSDG
                     QIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQTPDVEKPSDGQMPD
                     GEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKAD
                     EQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYV
                     IKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEA
                     VKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSI
                     NLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGKPSLSNGLT
                     KINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTGEVEISTQQKFKL
                     KSVVKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKN
                     GQEVNFNIGLPTDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVP
                     PTEDAVLNPPVPPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPK
                     TGDETQLMSYVFISVIAICGLAYQCKIKRN"
     CDS             complement(21698..23011)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RnfC_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3115"
                     /sec_met_domain="SLBB (E-value: 0.00042, bitscore: 17.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.8e-37, bitscore:
                     125.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.4e-15, bitscore: 53.2,
                     seeds: 53, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIYA
                     SVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKLNI
                     DLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKHPKA
                     IEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVINVETL
                     TRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKGEYGEI
                     ILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRDIATKMG
                     VTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCTDCSNTVM
                     GSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     CDS             complement(23400..24164)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3116"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 5.7e-38,
                     bitscore: 127.4, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKMP
                     IYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAIDE
                     KGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKAMDI
                     CSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDTIISR
                     LKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     CDS             24455..24658
                     /locus_tag="ctg1_3117"
                     /transl_table=11
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTAREN
                     GYVGGYMTKKLVEMAERQMAGK"
     CDS             24849..25385
                     /locus_tag="ctg1_3118"
                     /transl_table=11
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNYF
                     SLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDSNK
                     ENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKNNAS
                     YMYAEVIDLLIRDIH"
ORIGIN
        1 tattaaatat tatcctattt attggtatat ggaatcatat tgtttattat tttataatct
       61 tttcatcata taaacctatt aaatattatc ctaatttatt ggtatatgaa atcatattgt
      121 ttattatttt atagtctttt catcatataa acctattaaa tattatccta tttattggta
      181 tatgaaatca tattgtttat tattttatag tcttttcatc atataaacct attaaatatt
      241 attctattta ttggtatatg aaatcatatt gtttattatt ttataatctt ttcatcatat
      301 aaactattgt attctataaa ctgatacata tccagctgca gaagtacctg tcgtgcctga
      361 accaaatgta aaacttaaag taacagctgc tgctctagca tcaactaaaa agcttaaact
      421 tacacttaca tctgatgaag taagtgtatt tactgctttt gcaataaagt tattttgagc
      481 tactccatta aagttagtag taattgacat aaatcctgca agtgaaagtg tggcacgtat
      541 accgaaagat acattgtata tccctccaac tgcaagattt atagtactac ttgttggaaa
      601 agttatatta gttccattta taaatgatga attaaatgtc actaatgtat tattcactaa
      661 acttgaagag gacactgtaa attgtgcatt gtttgctgct aacactcctg ttgctccggt
      721 cgctccggtt ggacctgttg ctccatttgc tcctgttgct ccggtcgccc ctgttgctcc
      781 tgtcgctcca tttgctccag ttgggcctgt tggtcctatc gctcctgcta ctccatttgc
      841 tcccgttgct cctactgctc cggttgggcc tgttgctcca tttgcccctg ttgctcctgt
      901 cgctcctgtt gctcctgcta ctccatttgc tccggttgga cctgttggac ctattggacc
      961 tgctactcca ttcgctccgg ttgctcctac tgctcccgtt gggcctgttg ctccatttgc
     1021 ccctgttgct cctgtcgctc cggttggacc tactgctcca tctgctcccg ttgggcctgt
     1081 tgctcctact gctcctgttg gacctattgc cccagctact cctgttgctc ctgtcgctcc
     1141 tgttggacct accaaaccat ttgctccagt tgctccggtt gggcctgttg ggcctaccaa
     1201 accatttgct ccagttgctc cggttgggcc tgttgggcct gttggaccta ccaaaccatc
     1261 tggacctgtt gctcctactg ctcctgttgg acctacctct ccatctgctc ctgttgctcc
     1321 ggttgctcct attgggcctg ttgccccagt tgttcctgtt gctcctgtcg ctcctatact
     1381 tccggttgga cctgttgctc ctgtatttcc tgttgggcct gtagcacctg ttactccatt
     1441 tgctccggtt gctcctgtat ttcctgttgg acctgttatt ccatttgctc cggttgctcc
     1501 ggttgctcca gttagtccgg ttggacctgt tgctccagtt gctcctgtat tccctgttgg
     1561 acctgttatt ccatttgctc cagtcgctcc tgtatttcct gttggtcctg tagagcctgt
     1621 tattccattt gctccagttg ctcctttgtt tcctgttgga cctgttattc catttgctcc
     1681 ggttgctcct gtattccctg tcggacctgt tattccattc gctccagtcg ctcctgtatt
     1741 tcctgttggt cctgtagagc ctgttgttcc atttgctcca gtcgctccca tatttcctgt
     1801 tggtcccgtt attccattcg ccccggttgc tcccgtattt cctgttggac ctgttattcc
     1861 atttgctccg gtcgctccag ttgcacctct aggccccgtc ggtcctgttg gaccagtagc
     1921 acctgttggc cctgttggac ctacatcttg atataaactt ggacctgaaa tatcactcat
     1981 ataattaatc ctcctttttt aaagttagag tattactcta taaatattga gtattactct
     2041 atataattat atgaatcgac aatttcttat gtgataatgt atctatttgc ttatatcaac
     2101 atatatgctt tgattcttga atttcattac ttttttgtaa aatcttttac aattattagt
     2161 actcttttac aattattaat acaattaaaa aactcatttt ccatcaatta tttaaaattt
     2221 ttttattatg ttataaaaaa tagataatta aattgcataa aattaattta atactacttt
     2281 aattactttg taaataaaaa aacctcaaca cgattaataa aaatcatatt aaggcatcca
     2341 caaaattata taattgctta tctatcttca tcagtaacat tgaatatata aggaacattt
     2401 ctataataat caccaaaatc aaacccatat ccaaccacaa acttatcttc tatttcaaat
     2461 ccacaataat ctggcactaa atcgactttt cttctgcttg gtttatccaa aagaacacaa
     2521 cattttaaac tagcaggatt tttagctttt aaatgtttta acacaaaatc catagtaagt
     2581 gcagaatcag taatatcgtc tacaaccaaa acatcatatc ctgctatatc agtagtcaca
     2641 tctgaaacta ctttaaccct tccagtactt tcttcattgt ttccataact agatgtagtc
     2701 ataaaattaa ctctaagtgg taaatttata tttctaacta agtctgcaca aaatataaag
     2761 ctacctttta atagagaaac taccataaga tttttatctt tataatcttt ttctataatt
     2821 gctcctaatt cccttaattt atctttaatt ttttcttctg aatacaatac ttcccatttt
     2881 tttgtttcta tatccataaa aagacctcca attgtaataa tccttcttaa ttttataaga
     2941 gattgctcac tttttcaata ctcttattca atattagtca atattattga gtttttatgt
     3001 tcattcaaca attattaaca atgtatctta tattttaagt agttcatata tccacactaa
     3061 attacatact atatatttta gacaaaaaaa gaaaaaactt gcactaacaa gttttttcta
     3121 ttatacataa atttatacat aatcatattt tattagaggg tactaattaa atttatttat
     3181 gctatttttg ttatacctca taatacaaaa catattataa agtactagtc aactttattc
     3241 atatcattca ttacatttaa gattatctca tctgttatag acataccttt gtcacttact
     3301 ctacctaagt tttgtatact ttgctcaaca cttgaaccaa ctataccatt tagtggtggt
     3361 acaaaacaat cttgcttagc tattatagca ctttgtatag ctgcagatgc tgcagaagat
     3421 aattttaatg cacaaccagc tttcgcaccg tcacatatca ttccacttaa gtcagctatc
     3481 atattttcta tagctccttc tatttgcttt tcagtaccat tcataagcca agagatacca
     3541 gcagttgctc cagtagaagc agcaacacca catccacata cagcagataa tcttcctgta
     3601 tagttcttaa tataaccagt tactagatga gatatagcta aagcttttgc tagtctttca
     3661 tcagattgtg ggaatttttt attataagca acgattggaa gaattgctgt taatccatga
     3721 tttccacttc catttgaact cataacaggc atttttaccc ctgccattct tgcatctgaa
     3781 gctccagcag ttaacatcat tgcataattt ataacatcat tacctaaaag accttcttct
     3841 atagactttt taattccata cccgacacca ataccagttt tttgttttaa tccatattca
     3901 gccatctctt cattcatttt tactccatct agtaaaaatt ctatatcttt aaaatcaatt
     3961 tcttctacat tttttattaa ttcttgtata gttactgtat ccattaaact ttcagctttt
     4021 tctgccgcat catttgaagc tgatactttt ggttcattgt ctaataatac ttctccatct
     4081 ttttctaaga acgtaaaatt atcatgttta gttcttattc tcactttagc aatatgattt
     4141 tttcctttta acacaacttc tataaatact ttctctcttg tatcagcagg tgttattgat
     4201 agtggagtat tatccatata atcctcagct attttaactt cctcttttgt tagagtttct
     4261 aacacactta atccattttc agaatgtcca cctactatac ctagagctgc tgcaattttt
     4321 aatcctaatc tttcagtacc tggtatacct acacacatac catttttata gatactagga
     4381 ctaactaaca tacgattttc aactatttct tctcctaata attcctttgc ctttgcacat
     4441 gctagagcta aggctactgg ttcagtacac cctactgctg gtttaacttc tgcctttaac
     4501 atttccacta attcttttct tatatctctc attatatata aacctcccaa ttaagtttag
     4561 atttagtact caaataatta gttaaataat ttcttatcta tatttatagc aaaatacatg
     4621 ccatattttt tatatctttt tatattttta gtcttatatt ctataaccat tggtatgact
     4681 gcctctattt atgtattttt tttatttgta tagagtattt atattcttta aaatggagaa
     4741 acatatgaca atttcgcaaa aagacaaaaa aaagtctcaa aatgagattc tatatcattt
     4801 tgagacggct caaatatatt attttttaac ttataaaaac cattttttaa ttcataaaaa
     4861 aagattctgc aaaacactta tagtataagt ttaaagcttt ctttaaagtt atgaatttag
     4921 aaaaatttaa attttatata gctttttatt atattactat gaaattatat tgtatttttc
     4981 aatttttcta tataatgtag ctcttgatat tccaagtgct ttagctgtta attctttatc
     5041 ttttttataa tctttatact tatttaaagc ttttattatc tcaatcttct ctagttcatc
     5101 aagtggaatt atcctatcgc ttttaacttc taactcttct acagaggtat tcttaatttt
     5161 ttgaggaatt acattcattg tgattattga agaagaagac atattcacac tatattcaat
     5221 aatattctgc aactctctta tattccctgg ccacttatat tccatcatag catcaacaac
     5281 cctgctatct atgtcaataa catttttatc taattttttt gaatactctt taaccatatg
     5341 cttgattata agtgggatat cttcttttct ctctcttaaa cttggtaatt ttataggtat
     5401 aacatttaat ctataatata aatcttctct aaaagtgcca ttttgaacca ttctttctaa
     5461 atctttattt gtagcagcaa taattcttac atctattgaa acatttgatt tacttccaat
     5521 tttattaagt tccttttctt gtaatactct caataacttt gactgtaaat gcaaactcat
     5581 atctcctatt tcatctaaaa atatacttcc cttatgagct acttcaaaca ttccaagctt
     5641 tccacctttt ttagctccag taaaagctcc ctcttcatat ccaaataatt cactctctaa
     5701 taaattatcc ggtatagcag cacagtttac agctataaaa ggattatcta ctctattgct
     5761 atggttgtgt atggctcttg caaatagctc cttacccgtt ccactttccc cagtaataag
     5821 tactgttgat gttgatttag aagctattag ggcttccttt ttagaatttc ttatagctac
     5881 actttctcca attatgtttt ccaattttat tctataatct ttattcatct tattgtagtt
     5941 ttttatagca tctcttttat ctataaaatc aataacatat ccctttaact cattttttaa
     6001 tactatttta ttgatgttgt atattccctt cgaatcatat ccgtatcttt tataaaaaaa
     6061 actacaggat ttgtccttct taaagttatt tatagaaggt ttctttataa aatctaactc
     6121 gacaaatatg tttttgccag ttatactatc ttttatattg aaaagctctt taaattttga
     6181 attatattta tcaatttttc catccacatc aatagacaca acagctttgt ccatattgtt
     6241 taatagtgtc tctaattttt tcttttctaa ttcaagctca taagttttaa tttgtgcttt
     6301 taatttatta gatattaggt ctgccatttt gcctaaaaag tttataagac cacttttatt
     6361 attttctata atttgtgctt gttcttttgt aaaggctata aggcctataa caccatgaga
     6421 atcgccatca catataatag gacaacacac ctctgcaaac tctacacaag ccccactttt
     6481 atagcattcc ctacatatat cactactctt tgggtcatca attagtattg taatctgttc
     6541 tgtaagtgat tttttaaaag ccgtatattt atctactttc tcacctattt tgtctatata
     6601 tactcctgta cctgcaatcc taaataactc cttatttact atagttacat ctatattgag
     6661 tactgatact atagcttcag ctatattttg aatatcagat tttatatatt ctaaacctat
     6721 cataatcatc attccttatt tttctttagc ataagtattt gtcttatttc tttaagaatc
     6781 aagtatatct tatttaaagt aaattggatt gacatcagga ttacaaagag cataacaatt
     6841 attattaact cataatttat ttccatctaa acatctcctt ataacaaaag actaggctta
     6901 acctagtctt ttatattata tccatattta tattttaact catttatctt ctttttccca
     6961 cataaatata ttttaattta tttgactctt taatcatacc atcaaagttt aatcttgaaa
     7021 atatattaaa tacttcatgt ggatagtgaa tctttgcaac agaaccacaa aatttatgtt
     7081 taagatagtt taacttaact tttaaatttt ttaaatttaa atcctctaat ataacctctc
     7141 cattgccctt taacactctt tgtatttcag atgaagcttt ttcacaatct gtaataacat
     7201 taaattggtc aactattatt atcttgttga actgattatc atcaaatggt agaaactcta
     7261 acttaccttt aactacattg caattttcat tatacactag agaataacag acatcttcat
     7321 aattactatt ctccagtata gttacagaag ttccaagacc tctcaatctc ttgcctaggt
     7381 ttcctatatg accaacaagc aatattttat cacctacatt atactcaatt gtatccaaaa
     7441 aacattctaa ttcatcagat gtatatttag ctttaactgg ctgtttattt atctgacata
     7501 atatgctttt cacaatgctt cacctcttca tttcctcaat tataaattat gtacagatta
     7561 cattataata aatggcgagc aactattcaa gagatatttc attagtattt ttttaaacaa
     7621 tctttataca ttttaatatg atattatacc aaatttatta ggattttatt cataaaaatc
     7681 agtctatttt ttatgtttat tcattgttat tttcatccaa tttttttatt ttcgatatgg
     7741 atacttcata tgccattttt ttgaccacat tattttcatc tatttttttc tcatattctc
     7801 tactttgaac cctaccccaa agctgtattc tatcaccaac ctttagattc tttgcaaatt
     7861 tagcatttct accccaaact attgatggta tataatcaga tttattataa ggtctgttta
     7921 tagcaactaa taaatcggtt atttcccttc ctaaaggtgt cttcctatac acaggttcct
     7981 tacatacata tccatctaaa aatatactat tagggtcttt attttcctcg tctatacttt
     8041 ttatttctct gacaaacact gtaagcacta atctattttt attatttaat gttttgttat
     8101 atgatcttaa ttggcctacg acattgacta aattttgttt atcaaggtca atatcttgga
     8161 gaagtctttc tgatacagtc attggaagta tatcaaaaga atcgcttagt ctgtttattt
     8221 ttattttcat attataaaat ttttctccaa atatctcatg gctaaattct agcttattgt
     8281 ctaactcccc tcttaagttt actacgttat tctcatcttt aacagctatc atattttatc
     8341 cctccacaat tgttaattct tatatttctg gtatcagctt atataataaa tatatttata
     8401 aggaatgtat tttattacaa atctttgatt gctgtttaaa agtttttatt tagttataaa
     8461 tttcatttaa tatttcactt ttataattat aaaattatta tctttttgta ccacatatac
     8521 taattaaact acctatttca gttttgtatt aattataaaa atcctattat ataattaata
     8581 agtcatatat aacttaaatt tattcactct atataagcaa cttcaacgaa ttaaatttat
     8641 tgaaataatt cagatgaata ttgagtcatt ataaacttat ttttcttaat tataagttat
     8701 attagactta ttacaggtta tatttttatt aatctgtatt aatatatgaa catttattga
     8761 acttattgat tataaaattt aaatatttag ctttaaatta tgctttattc tttaaaaata
     8821 caacgttttt tagattaaat ctactaaatc actatatata ttacataatt ggcatgttaa
     8881 ttgctttata ttaatttagt aaataaaaaa ctgccctaaa atattaattc aatattttaa
     8941 agcagtttat aatctttatt attagctgta atatttaata aacactaagt agtctttaac
     9001 taagcagtct ttttgttttt atttgcagcc attatcattg tagcagaagt ataagctata
     9061 actactatta ctaatgcttt taatatatcc attggtagag tttttactat atatgcagct
     9121 acgaaaactc ctattaaacc acatatagct attataactg atgctttttt agtatatgca
     9181 tcttctttta tgaatttcat acttgcaact ggcattaata atgcacaaga acccataact
     9241 attgggaatg caacttttgc agacattcct aagaaataaa ccattgccat acctggagca
     9301 tatagaccta taccagctgt cattaaagct cctagtataa agttacctat tacacctatt
     9361 actaatttag caccagtaag acctaattca tttcctccac ctggtaatac gttaatccaa
     9421 ggatgaccta ataacattaa tattgctgtt aatgctaaag ttacacccat aacaagttgt
     9481 atttttctct cgtccatctt agctattatt cctgcaccta tatatgaacc aactgctgct
     9541 gccacaacca tagatactaa agtaacacca tctactggga taattgatgt aaatatgaat
     9601 gcttctgtaa caactggaat agtatgtgct acgtttaatg taccaggcat ttttttatct
     9661 ggtatattta actttaaagc ctttgacatt gctattgttg gagcaaatga ccctattcct
     9721 aatgtatcaa agaagtctgt tataaatcct gttacagcaa cttttggagt actttgttct
     9781 tctagtttcc cctctttgtt tgctttagct acgtctttac caaacacaac tgcaaagatt
     9841 gctgcgaata ctacatataa tgcctttaag attgctacca taatccatcc tcctattttt
     9901 ttattttttc atatattctg aatcttatag cctaaaagct atagaatagc aaccgacaag
     9961 tggctactat tctattttaa tttcctaatt tatttattac ttatttaaga ataaatccat
    10021 gtttaagtgg gtcttcttca tctattacaa aatgattaaa tccagttata taagcagaac
    10081 cagttatttt aggtactaca gcattgaaat ctgcaacttt agtttcttca actatttcac
    10141 ctttgaataa agttcctaat atactttcat atacgaattt ttctcctact tttaattcac
    10201 ctttagcatg taaagtagct aatttagcac ttgttccagt tccacatgga gatctgtcaa
    10261 cttgaccttg accaaatata actacatttt tgtaagtagc ttctggatga gttggctcat
    10321 catatatttc aactaagtct acagttttta tatgagctaa agttggatgt tgtatttcta
    10381 ttttctcatt tattatatct ctaagtttca tagctagttc agttaattta ccagcatttt
    10441 gaggttcgat ttttaaacct aattgacttg catgtattat agcaaagaag cttccaccaa
    10501 atgatatgtc aaatttaaca gttccaacac ctggtaagtc aacttcaaca ccttctttat
    10561 ataagaaagc tggtacgttt aagaatgata cttctttagc ttttccatct acaactgtaa
    10621 cgtctcctct tattattcct gctggagctt ccataactac atgagttaca ggctctactg
    10681 ctggaactac acctgtttct atagctgctg tcatagctcc tattgtacca tggccacaca
    10741 tgttaaggta tccgccacca tccatgaaga ttattccaaa gtcagcatct gggcaacaag
    10801 gttgagtcat tacagaacca aacatatcat tatgtcctct tggctctaac attatagcag
    10861 ttcttaaata atctagattt tcctctaaat attctttttt ctcaggcata gaatttcctt
    10921 ttatgttagg tattccacct acaactattc tagtcgcttc acctgctgta tgagagtcta
    10981 tagcttgtat acttctgcta aatttcatat caaattcccc cttaggttta ttttgcgtct
    11041 ttacgcattt ttaattttag gaaagccaat gcttttttaa catcaacttc atccatgtga
    11101 ttgtctccaa ctacttctgt ttctatgtag cctgttgtct ttttataatc aattatggta
    11161 gctttatcca aatatggatt ggtaattact aatccatctg ctcccataat agtaagacct
    11221 actgtaggta tatctgattt tacaaactct gctatagcat ttgtaaaatc aatatgctgg
    11281 tttcctgcca tatctaaagt tataatcact ccatcaggtc gcaatgattc aatccatctt
    11341 ccaagtctag ttgctaaaaa tgttttccat tcattgtgct ctgatgtccc aactacaacc
    11401 actcctaaca agtctatgtc agaatcatta tctatcaaat ctagtaacgg gtctctaaat
    11461 atatgaagtg atgtgttttt cattgatgta gaaattccca caaaactcat tcccttactt
    11521 aaatttttta tccatgtttt ctcattttaa gttttaaaaa tgccaaagct tttttagcat
    11581 ctatttcatt tgtgttgttt tctccaacta cttctgtctc aataccttct tttgatttgt
    11641 tcatatcaac tatggtatcc atatattgat tgcttacaac aaacttagct tgagtcccat
    11701 taaatgtaac tccaactaca ggtatatctc tttttcctat ttcctcaaat gtgttagcgt
    11761 agtcaacatg tgagtttccc caaccatctg atgaaactat agctccatct actctcatgg
    11821 cttccagcca agcggccgtt ctttgtccca caaaggtttt attttcattt ccatctggag
    11881 ttcctactac tattactcca agtaaatcta catccttatc actttcaact atgtctaaaa
    11941 gtgggtctct aaagtgatga agagatgttt cttttgttga aggtcctatt cccataatat
    12001 ccacctctct taagtcatag ctctaagggc accatctctg tattcattag gagatataat
    12061 cataggtaca tttcccatat ctataattga tgttcctcct tcaaatccac taggttcctt
    12121 tgagaataac tgattgtcat acatagcacc ttgacctgct atttgtttta ctatgacaac
    12181 cttttttgca tttggtcgaa ttttgtcaaa atattcacga acttgagtag catttcttcc
    12241 gtcttccatt ttcaaagacg ctcttatttc ttgtataaaa tcatcacatg ctctgaatgc
    12301 tgcaagtgga agtgttcttt caaaaggtaa acctcccttt aaagttacat ctacatggat
    12361 tatataatct tcaactgatg gagttccata tctcccaaat accatttggt ctttcaaaat
    12421 tccttctgaa gaaccaaatt catgcatttg atttccatct tcatctgcac cagttaacat
    12481 tacatataca cccgttaaag tatgtgtaat accctctccc agtctgccta aaacttttgt
    12541 tgatattggt ataatgtcca taatagtatt aatttctctg tcataatctc caggttttat
    12601 aatgtctact tttatgtctg ttattaactc ttctctttct tttatttcat ctatacttga
    12661 taaatctatt gtaagtacat ctttctttat agaagttttt gaaccgaaat taacttcatt
    12721 catatgaaac ggttttataa caagtcttct cattattttt tcttccataa tatccacctt
    12781 tgttcttaaa acccctctcc taaccgtgta ggagaagggt tctatatttt caaatataaa
    12841 ttacatttta aacgtgagct ttatattcgt atggtaatgg aactatctta ccagcagatg
    12901 gtattgcaac taattgctct aatgtatctc ttaatatatg tgtttgcatt tctatattat
    12961 gtggttcacc agcattagca cccattggaa ctaatggagc aactgctcta ggagttccgt
    13021 tttgtctaac tactggagga agagctgcta ttattattgt aggtattcca gcttcctcta
    13081 ttgctctctg cacgatcacg gcagttctat ggcaagtacc tcagccagct gtcataacta
    13141 caccgtctac tccctcttcc ttaagtttag cagcgatagc aggaccagtt tcttcagtga
    13201 agacatgttg gtttcctcca ccacccatga atgcatagtg cataggagct actcctttga
    13261 taaatccttc tgcagctaat tcatgtaatc tatctatagg gaacatacag tttatatctt
    13321 tgtttacatc tccattgtca tatccaccat gtgataccat catttcatca actgtagctg
    13381 tattaggtat agctctaaat gtagtatctc ctgctagatt aaatctcttg tcagatttta
    13441 aatgaacacc agctgctgta gctaaagcta tagtcatatc ttttaattct ttagttacag
    13501 gagtccaaac tggaggaggt gttattggaa cgaatatttc agattgaagt ccttgtactg
    13561 ttgtaaggct catatatttc ctctcccttc tattttcaaa cgattattta ttatttttct
    13621 tcttgttttg attgcatttc tgcttgtttt tctttttctc tcctaatatt ttctacatac
    13681 tcttgattag gctctggact taatacctca ggatagctta gcatgaatcc aacttcttga
    13741 cctatcttaa gttcgtagtc agttataagc attctattag gtattttaaa ttgtccaagt
    13801 ctacctttta ggtctatagt cactccaccg cctttgatgt caactataat accttcataa
    13861 aaagtctctg atgagatata ttttaaccta tccattataa ttctacctct ctatactgtt
    13921 ttaaacttgg atctaaattt atgttattgt ctaaatctta gttagtatct aaattttagt
    13981 tttcgtcttt ttcgtatatt tctcttctct tcttactcat tggtagagat tgctcattct
    14041 cttctaatac tattttttct cctgtaactt tttctatagc ttctatgtta tttaatttaa
    14101 catttggatt ccattttctt tcaggagctt taacttctac accttctata gcatttttaa
    14161 gcatagccat tattctaaca gcatcttctg gagctaaagt gttgttagat aatatttcat
    14221 tctctatacc ttgcttagac ttattgttgt ctaccatgtg agtcatgtat ttattaccaa
    14281 caactagagc accttgaaca gctgagaaac ttacaccaac tactggtata cctctcatac
    14341 ctatttgctc tatgtgagat gcgaaatcta tatggttgtt tccgaaacct tcagtagtta
    14401 ctacagctcc atcaacttcc atagcttcaa ctaacatacc taatctctta gatacataga
    14461 atttctcagc atttacttgt ggagaaccaa caaatacaac acctactaaa tctatttctt
    14521 cgtcttccat agctcttatt actaatggct ctctccagta atgtcttgac atttcttttg
    14581 atgcaggtcc tatacaagtt aatgcatgga taccaccatc taatacttca agtggagata
    14641 atacaactgg catgtttcct aagtcaacgt ttggttgagc tcctaatgta ccaactggct
    14701 caactggtaa tattaggtta tcatgcattg caccttgtcc cattatttct tttataacaa
    14761 caactttctt tttaccttct cttctgtatt gctctattac ttcttcatca actactaaag
    14821 agttgtcaac tttctttaat gcttctctta tttcttgagt tacatagtca aatgcacggt
    14881 gagcagctaa aggtcctggt ctttccatgt tagttcctgc ttttattgtt acttgacctt
    14941 tgatgaatat ttcacctttg tcagcagcac ctggtctacc ccacattata gtagtattta
    15001 actcaccttc tgaagaacca aattcaccta tttgaactcc atcttcatct gtaccagtta
    15061 ataccattac agctccatct ataactctag ttatacctga acctaattcg ccttcttctt
    15121 tagtagcgat tggttgtata tctaatacag cttcactgta agtttcatat ttatcaggag
    15181 ttattatttc taacttcata tctacaacta actcttgagt ttcattagct tctttacata
    15241 tttcttctgc gtttctgatg tataaagtag ttccttctat tttagtttca tcagcaaatt
    15301 caactttatc tattttaaag tgttttttag ttaagcttct taaaagtttc ttttcttcaa
    15361 cttttggagc tacttctgct gctgcacttg ccactggagc agcaacgttt gctactggag
    15421 cagcaactcc tgcttgacca gctactgata aaggtatctc taagcttatg ttcttacctt
    15481 cacctatgtg tattttaact gtttcacctg caactcctgt gcttactgga actactgctg
    15541 cttctgatac tggagctgct tcttctactg tttcttctac tacttcttct ttagcctctc
    15601 ctgctttgta tccttctacg ttatctgtag tcattggaga aagtgcatct aaagtttctt
    15661 ttaacttagc tcctagtact tgacctatag ttaatccatt ttctggtatt gttaataatc
    15721 cagaatcctc taagtctgca aatattgctg gatcttctaa gttttctggc gctataattg
    15781 ttcccgcttc aaatctacaa caacaaactg ctgggtcatt tgcatgggct tgagctgttt
    15841 ctaaagttat tgacatagta taaaatacct ccttacatta ttttcttatt tattatttta
    15901 aatctcaatt cctcaacagg taacccctta actgagaaat taagtaaatt aaaacctaca
    15961 taatttgtta tgattaatat tatttttttc tcacttaaag tcactttata ttataagcaa
    16021 ttcctatgcc aacttattaa caaaaagatt ttttctataa tagattcttc atctatcgct
    16081 atttttagcc aaatattata taaatattta tttaaaatat gttatttttt gtatttgtaa
    16141 acattttctc aaacaaaaaa agtgtcaatt aatcaacact ttttcatttt ttttaacaca
    16201 tctatataca caacacttat ataagcgttg gctttactag gttttaaatt aaagtttatc
    16261 attttgtcaa aatttagtca tgtgtcatat tttagacaca tctattttgt attggtctat
    16321 cttataatac aaagttgttc tgggtatatt taatatctta gctgctttag ctttatttcc
    16381 attagacatt ttaagtgcct tggttatatt ctttatttca attttttgag ttgccttcgt
    16441 taaatctaaa ggatactctt cttcttcagt actattattt gtagaatcca tcatataact
    16501 tggtacatca tccacatcta ttttagaatt ttgtgacaat acaacaatat tttcaatcgt
    16561 attttttaat tctctaatat tacctttcca tctataattc tgaaatatat ctattacatc
    16621 tttgctaatt gtaagaacag gcttattatt ttgtttacat atctcctcta aaaagctatg
    16681 aaccaataat cctatgtctt cttttctctc tctaagtgga ggaatcttta tttcaacaac
    16741 atttaatcta tagtataaat cttctctaaa tttttctgcc tttaccattt tactcaaatc
    16801 tttattggta gctgatatta ttctaggatt tatttttatt gtggtatctc caccaactct
    16861 tcttatttct ttttcctgta atactctaag caactttgct tgcatactaa gaggtaaatc
    16921 ggcaatttca tctaaaaata cagttccatc ttttgcaagt tcaaatatac ctattcgacc
    16981 ctttttactt gctcctgtaa acgcacctga ttcataccca aaaaactcac tttcaaataa
    17041 ctcatttggt atggcactac agttaacagg tataaattga ccttttctct cactataatc
    17101 atgaatagct cttgcaaata cttctttacc tgtaccactt tcgccccaaa taaatatgct
    17161 actatttgtt ctagccactt gttttgcaat cgctttcgat ttttccaatt tataactttt
    17221 acctaaaatc ttatcaaaac tacctttaga taaatttttg acttcgttct ttagatattt
    17281 taatgtatca tttacttttt caagttcaag agctaatatc ttagcttctg taacatcaac
    17341 ttctgtacat acaacaccga taaattcttc tttataaaat ataggatttg catgaactaa
    17401 tgcatacata ttttcttttt tatctgtaaa atacaagtca ctcattccaa ctttactatt
    17461 tagtactttt tctgaaatag tattttccaa aaattcattc atcggtcgac caactatatc
    17521 ttcagacttt atatcatacc tttcctccat aaacttattc cacaagataa caacaccttc
    17581 gttatttata gcacaaattc cttctttaat ttgacctata atatacttca aagttaatcc
    17641 ataatcttct aaatgcatat atagatagtc cctaatgtgc tcttgtttta gaactccaat
    17701 aattttatta tctctaagaa caggaagaat ccctatattt tttaatatca ttatatctct
    17761 acattcatct aaggttaaac cttcgttgac atatattaca tccttcttca ttataagttt
    17821 tactggttga ccttcatact ttttatgcat ctcataaaga ttatgtatat ccgtcatgga
    17881 tataatgcct tttaattggt cagatgaatc tattaccatt agagtttttg tgttgctttt
    17941 tatcatttct tttattgcat cttcaattct tgtgtcttcg tctatagttg taaattttgt
    18001 atccattacc tcttctactt tttttacttc tggtatcgaa aacataaagt ccccccttta
    18061 tagtagtacc tcatcaaaac ttatttatat atatttattc tagcatatta taataattat
    18121 ttattaaata attattatta aaatttatta agtaattagc atttaaattt atataatcac
    18181 tttaaaattt ataattaaat ttatacaaat gaaatcaaat gaattatacc cttagtatat
    18241 tattttttca atactatttt caccttcaaa acatttttct attcatcaaa caattaatga
    18301 atgcctgtat ccaatcataa atttaagaat ataattaaaa tatatatttt taaacaaact
    18361 atatttgcat attatattta cataaaaaag ccccaaaatg acttataaat caatttgaga
    18421 ctttttattt taaacttaat aataatctag attaatttct ttttatttta cattgatacg
    18481 ctaatccaca aattgcaatg acactaataa atacatatga cattagctga gtttcatcac
    18541 ctgtttttgg tgattttatt attgtatcat ctcttgatag ttctggagtt ttttccactg
    18601 tatcacttac tgatggtact ggtggattta acactgtatc ctctgttggt ggcactggtg
    18661 gatttagcac tgcatcctcc gttggtggca ctggtggatt taacactgca tcctccgttg
    18721 gtggtactgg tggatttatt attgtatcat ccattggtgg tactggtgga tttattactg
    18781 tatcatctat tggtggtgat ggttttggct tatgtccatt tgtatcatct gttggtggca
    18841 ctggtggatt tacaacatca tctgttggta gacctatatt aaagttaact tcttgaccat
    18901 tttttttctc tattgtataa cttaataaat tttgcttact agatggtaat gaagatgaat
    18961 ggtctttttg tcctaaatca agcactgcct tataatattg aatagctttt ggaaaaatat
    19021 aatcataaga tacagcagaa atattagctt tggcatctgg ttttacaaca ctcttaagtt
    19081 taaatttctg ttgtgttgaa atttctactt cacctgtacc tattatatta ccatctccat
    19141 cataagcagt tactccatct ggtagtctta actttactac accactataa cctactaagg
    19201 ctacagcttc tgtttcataa gtaccatctt catttttttc aaagttaatc ttagttaaac
    19261 cattactcaa actaggtttt cctgtatcat ttggctttaa ctcttcacga cctgctttta
    19321 acaatgcttc taaataagct tttatattta tagctacttc tttcttcttc tgatactcag
    19381 ctctttcctc ttcagttttt gctctttcta taagtttatc acaaaggttt atagaacctt
    19441 gatactgctt aagtctttct tgttcatcca tttgtccaag aataatccaa attgcacttt
    19501 gagtagctga gtaagtcatc aattcatttt cttctccacc taaattaaat tgttgcttat
    19561 atccaaatcc atcaaattca gaacctgcat atagtataga tttaactgct tcttcatttt
    19621 ggttttcttg accattaaaa tcttctgctg gtaaatatgg actctttcca ttactacttg
    19681 gtggtcttaa atgattattg taacaaaatg cagtttgctc tccatcttca ccttctatta
    19741 catatttgtc gtcttttgag cttgctccta caagaccctt tattacatag tcaaaagtta
    19801 aagtctttgt aatatcatca aatcttaaat catgataagg tctatctgaa ccatctattt
    19861 cttttagtaa acaagaattt tttacttttg cttttttgtc ataccataag ctaataaatg
    19921 agtcttctga agtaaaaact tggttaattt ctgattgttc atctgccttt acatcttctt
    19981 catcttccca aaagttatat actattttat ttatttgaga taaagtcata tcaagaattt
    20041 tatcaatatc ttgttttaaa ctcatttcct ctataactat ttcttcttcc aatggttttt
    20101 cttcttctgg agtttgctca tctaatggtt tctccccatc tggcatctga ccatctgatg
    20161 gtttctctac atctggcgtc tgactatctg atgtcttctc tccatctggc atctgaccat
    20221 ctgatggttt ctccccatct ggtatctgac catctgatgg tttctctcca tctggtatct
    20281 gaccatctga tggtttctct ccatctggta tctgaccatc tgatggtttc tccccatctg
    20341 gtatctgacc atctgatggt ttctccccat ctggtacctg accgtctgat ggtttctccc
    20401 catctggtac ttgactgtct gatggtttct ccccatctgg tacctgaccg tctgatggtt
    20461 tctctacatc tggtgtctga ccatttgatt gttcttctcc attaagtatt gtatcattgc
    20521 tagtcacttc gtcagcataa gatactattg gtgtaaatgc agtaaacacc atactaaaag
    20581 caattactaa actgattata cttgattttt taatttttgt tttcaaaatt ctcctgatac
    20641 taaaaacata tattgtattc acttaatata attaaaatta ttaaatatta tatgaatctt
    20701 attcaataat acatctttag tgtgttcaat tagggtcgtt actcctaacc agttctccta
    20761 tgaacttctt aatatttcta ttaagcacag actatatcat tacctaacca taaattaggt
    20821 actccccatt tccccacact tgtaggtacg agatttctct ctagtcgttg aagtttcttc
    20881 ttttcgaagc ttacctgctg attatccatt ttcaaggcac ttaggattta accttatgct
    20941 atctaactaa ttttttctac tttcgtaacc tcaagtgctt attaaatgca cactctatca
    21001 cacttatcct tatttcatga ttatgttgtg gtttagttag ctttaggaac ttccagcaat
    21061 taaaggagtt ttgggcagat atctgccact ctacactcgt tatgaatgca gggagcattt
    21121 caaaaatata tttatatcta tcttctatta attacttatt tatgtattta ttttatatat
    21181 ttttgacaat taaaagttac tcctatttat atttatagca ggttgcacta ctaactccat
    21241 atatctttta agtgcccagg tttaagatat acttcacagt ttctataaat aggtttttta
    21301 atttttcttt tttaactttt taagtgcact tttttaacaa ctcaataaaa tataaattag
    21361 tatcctagat acttatctaa taaaagacaa aaattagttt ttataataaa aaagatacta
    21421 tagagtatct tcaaatatca caaaaacctt ttactctatc ggatagttga cttaatataa
    21481 tatgcatatt aatacaaacc acatacttga gtatcattat ttttgtccaa tattaattgt
    21541 aatagctatt attatcatta tacaatatct agcatatttt gtctattttt tccatttatt
    21601 ttacaatata tatattgccc tcaaaataca ttaaaaaaca tccttagaag taacttttaa
    21661 gttttacttc taaagatgtc taacttctat ttatctatta ttttattttt aatcttacgt
    21721 caccttttat tcttcttatt aatgggtgat taactgttct cattacatgg tcagtaatat
    21781 gatatacacc taattttaat tttggtgcag aacccattac tgtgttacta cagtcagtac
    21841 agtttcctat taatataact tctgctccag ctttcttaaa ttcaatacat ttttgagctt
    21901 gtcctggaca gtgtcctgga ttttcacatt ttaatgcacc tttaatttct tgagcttgtt
    21961 tacatttttg aactgatact atatcagtaa ctcccatttt agttgctata tctctcattc
    22021 tttcttcatt aggtccacat gcacaaacta aaagacccat ttttctcttt tcattaacaa
    22081 atggcatagt aactattata ccaccactag ttttagttat tggagcatct aaagtagtag
    22141 ctttaccagt gaaaggtcct cctaggatta tttcaccata ttcacctttt attccaccag
    22201 ctctttcaat taattctccg acagttgttc caattggcac atcttcaaac actatagatt
    22261 cttttccact gtttaattga ccaactacag ttatattttt agatataact ggtctttttt
    22321 gctcaacagc ctctactatt ctagttagtg tttctacgtt tattactact gcattagcct
    22381 ctgaaggtaa ttgagttggc tcaagtaatt ttcctagaac gtctcttact attgctctct
    22441 cttctcccat tgggtacata tcaactagtt ctgcaacttc tatgttgtct cctggcttta
    22501 ttactttttt gaaagcttct attgcttttg gatgcttact ttttattgct agcatacctt
    22561 ttccagcatt agtaacttcc atagcatatt ttataccttg ataaactatt tctggtcttt
    22621 cttctatttc ttttatatta tgagctaata aaggttcaca ttcagctgca tttgctaata
    22681 ttgttccacc atttaaatct atgtttaatt ttacatgagt agggaatcct gctccaccca
    22741 ttcctactac tccagcttct ttaattaagt caagtatacc ttctcctttt aatggttcaa
    22801 aagtatcttc ttgtacttca tcagcttcaa ttactatcgc ttggtcattt atttcactta
    22861 tttttccact aacactggca taaatatttg cccctaatcc agttggttct gcgattagag
    22921 ttcctttttt tactacatct ccaacactta ctactggctt atctggacca ccaacgtgtt
    22981 gttttaataa aatagaatat agtttgttca actagtacgc ccccttaagt atattaattt
    23041 ttttataagc tgttcaaata atgttaatgc tatttttcta ttataaggtc ttaacatatt
    23101 gtttatttct atagaacata tcgcttatta acaaagcaat ttctatgcca acttttaaac
    23161 aaacttatac cctttggaaa tactgtctta cagcattcat taattcttct aaatttttaa
    23221 acccatcaaa aaaaagtcaa ttattagaca cttttttaat caatttaatc tataattatt
    23281 gatattgcat acatgtataa aaagtgtcaa aaaatagaca ccgtcttttt atcgacactt
    23341 ttctaacata tactatataa tttatcacaa ctttacttaa aatatacatt tattacttat
    23401 taattcttag ttttttgcac tccattggaa tcaactacat aattatcttt atacaacaaa
    23461 tcagatattt tgactagact gtatccatct ttttttagtc gacttattat agtatccaaa
    23521 tagttatcta catcatttat attagcatgg aataaaacta ttgaaccagg ttgagattct
    23581 tttattactt tttcaattac atgatttggt ccaagctcct tccagtctat agaatctaca
    23641 tcccacttaa ttactttata acctaaatca ctacaaatgt ccatagcttt attgtttacg
    23701 tccccaaaag gaggtctaaa taaattagtc ctttttcctg ttatattata tattttttct
    23761 gatgtagttt ctatctcttt tgttatgtct tcttttgata tttccttcaa attggcatga
    23821 gtatttgaat gatttccaat ttcatgtcct ttttcatcta tagcttttac aatttcttca
    23881 ttatcatcca cccaactacc aactaaaaag aaggtagctt ttacattatg tttatctaaa
    23941 atttttaaaa tatcatccat attatcagtt ccccatgcta catcaaaact caaagctatt
    24001 tttttctcat ttgtatcaac tttatatata ggcatttttg aattgtcaga tttagaacat
    24061 atgtatttta ttccataaac aaaaacaaat attaacacta ataataatga aaaaaataaa
    24121 acactatata tcaaagcttt agtcctttta acttctcttt tcatactatt ccccctttga
    24181 aataatttct tctatattta aaatttattt tttttcagct caaaaaagta ctgtaatatt
    24241 taatttataa gacaataact aaaaaaataa aacctatatt gacctaatta aactctctaa
    24301 aatactcatt tatttaattt ttttatattt tttacatttt tacctttatt tttctgtata
    24361 tattattttt attttggaga aattagtatt aacatcacat aaataaaagt gttgttagac
    24421 atcataaact aattatttga ggaggaaatt tactatgtca aattcaaaca gaacagtagt
    24481 tccagaagca aaagctgctt taaaccaaat gaaattagaa atagctaacg aaataggttt
    24541 atctaactat gaaaacatag acaaaggtaa cttaacagct agagaaaatg gatatgttgg
    24601 tggatatatg actaagaaat tagttgaaat ggctgaaaga caaatggctg gaaaataaat
    24661 agtaaatttt gacacctggg tatcaacagg gctgctaatt agcagccctg tttttctata
    24721 tttatttata aaattgtttt tatatgaatt attaaagatt aataatacaa tacaaattgt
    24781 tcttttaatt ttgtacaaat tagtttaata tattatatat agaaatagtt tgacggagga
    24841 tgatatttat gtttgaaaac tcgtctgaag aattagccta tcacaaactt ttaattttat
    24901 atatattaga aaaaattaaa atggatttaa ctaattctca aataactcaa gtagtattag
    24961 agactgagat gatgaattat ttttcattac aacagctttt atctcagctt atggaatcta
    25021 agtttttgac tacatataaa gactctgaca gagaatatta tgctcttact caaagaggcg
    25081 tagaaagtct agaatacttc tttaatcgaa tacctactag tgttactgaa aaaatagaca
    25141 agtatataga ttctaacaaa gaaaatctac tagcagatac tcaagtaaag tctagttttg
    25201 taaaacaaag tgataatgaa tttattgtca accttagagt catagaaaat cagtctaact
    25261 taatagattt aaatctaaat gtttcatcag agaaacaagc aaaacttatt tgcaataact
    25321 ggaaaaataa tgcatcttat atgtatgccg aagttatcga tttacttata agagacatac
    25381 attaaagcct acaaacaaat tatagttgta ggctcttttc ctaccttgat ttcttttatt
    25441 aatttgttat ttgcagtttc ataaactttt actgaatttt cttgtgtatc tgatacaaat
    25501 agtaactttt catctttaga tatttctaat ccttggggaa tcccatttat ttcaatattt
    25561 ccaatgtatc tactcgttgt ataatctaaa attcttacat tattataacc caaatcagca
    25621 acataaactt ttttgccact ataattaaat cttatttcta ctggtaataa aaattcatat
    25681 aatacctttt ttatatccat gcttacttca tctattatta taagctttcc atcaagtgtt
    25741 gatatataca tttctttctt ttgtttatca agttctatat gccaagctct aaagtccata
    25801 tttattttct tttgtatatt tttattaatt gtatctatac atactatcga gtttat
//
