LOCUS       NC_009495.1            33995 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_009495.1 Clostridium botulinum A str. ATCC 3502, complete
            sequence.
ACCESSION   NC_009495
VERSION     NC_009495.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:43:47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3644627
            Orig. end    :: 3678622
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..33995
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3654627:3668622]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..23995
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..33995
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="interleaved"
                     /product="OD_fatty_acids"
                     /product="porA"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..33995
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="OD_fatty_acids"
                     /product="porA"
                     /region_number="14"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and (minimum(2,
                     [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(545..1204)
                     /locus_tag="ctg1_3304"
                     /transl_table=11
                     /translation="MDNKYNDLFYWENLLLKRENVWGGNFKDIPISPKSLFINTTIIDY
                     EKNIFDNNWAVYPNVESLLGFVKYIFIPTVFFCYTNNTNEEIVTPIVSKEELLGEIKTL
                     CRNENSIVEIEYFIDKAYNLCELNECHLIEELKKYCLEFNRKWEEKTRVFHISIYSSGK
                     EIIQKISKEDDFLEVIEEDIGMPINTLKEITKDLHHNLFMKNNFIKILNNQIGCII"
     CDS             complement(1457..2050)
                     /locus_tag="ctg1_3305"
                     /transl_table=11
                     /translation="MAKIRDPRFKLSRRLGVNIYGHPKAMKRATRENSREGKKLSNYGK
                     QLLEKQKIRSYYGVLEKQFLRYVKKAMKSKERTGDVLLRSLECRLDNIAYRIGFANSIR
                     QARQMVNHGHILVNGSKVNIPSYEVKTGDVITLREKYRKNDEFADNFLALKKFSLPYIE
                     KDYDKFSGVLIKEPERDEIPIDANETLVVELYSK"
     CDS             2496..3668
                     /locus_tag="ctg1_3306"
                     /transl_table=11
                     /translation="MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGF
                     LIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLFTLISGFSALLVGRTLLPSIITSAT
                     HVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDVAIGFQEIITKV
                     IENVVIPLLPLHILGIFANLAYTGEVSTVLKVFWKVFIIILILHWIILIFQFSVGGSIA
                     GKNPFKSLKIQIKGYLTALGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSG
                     STITLTICALSVMLLNGMPISMSQMAGFIAMLGVTMVAAPGVPGGAVMAALGILQSILG
                     FNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKKSDKKHNKNI"
     CDS             complement(3855..4448)
                     /locus_tag="ctg1_3307"
                     /transl_table=11
                     /translation="MNMNMEFFRLINNLANKNSVLDKIMIFFSKDIPYIFMAIVAIVFI
                     LGITKKNCDYRKVAFNTFIIAVINLTISFIIGGVYYVDRPFVHNKVNLLYIHTKNSSLP
                     SDHAIGTMSIALGLRKYNKLLSLILTVFSIIVGFSRVYVEHHYPLDIIGAYIIVFTTNY
                     IYNLKLRNKVESLYEAVEKKLVEKFGFEKICNKI"
     CDS             complement(4681..5127)
                     /locus_tag="ctg1_3308"
                     /transl_table=11
                     /translation="MFIEMELTHEDYKVDIAYDGRGALEKVENTEYQLILLDIMIPGLN
                     GIEVCRRIRQFSCVPIIMLTAKSDVSDKVLGLDVGANDYLTKPFAIEELLARIRVYERE
                     KLVESKFDEIKVKDIVMDNKTHQVGGLAEKLNLQKKNMIFLKSC"
     CDS             5517..5999
                     /locus_tag="ctg1_3309"
                     /transl_table=11
                     /translation="MANLTQKEQLLLQDQKSHEELCIKKYTNYANQSKDPQLKQIFLNN
                     AQEEQEHLNSINQLLSGQIPNVNSQQNNQQQNNQQQQNSQMQSNTGTGLATTNDADLCT
                     DLLATEKYVSSTYDTAIFEFRDPNIRNVLNHIQKEEQQHGEAIYKYMESKGMYNPQ"
     CDS             complement(6205..8031)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3310"
                     /sec_met_domain="SIS (E-value: 4.5e-32, bitscore: 108.4,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYVGFRKASDVIVDGLSKLEYRGYDSAGIAVNDGKEIEFQ
                     KYKGRLNVLSENLESKPMEGTIGIGHTRWATHGVPSDVNSHPHLNMDETIAVVHNGIIE
                     NYMEIKDWLSSEGVKFKSETDTEVIAHLVDHYYEGDLLQAVFKAIKKLRGAYALGVVCK
                     DNPEQLVAVRKDSPLIVGIGENENFIASDVPAILKYTRDVYFLDNGEVVTLEKDKIKIY
                     NEKEEGITKEPFHVMWDVEAASKGGYDHFMIKEINEQPNGIKETLVRRLDENGKIKLDD
                     IKLTKEDLDEINKVYIVACGTAYNAGITGRYAIERFAKIAVETDVASEFRYRNPFIDDK
                     TLIIVVSQSGETADTLAVVREGKEKGARVLAITNVVGSSIAREADDVFYTWAGPEVAVA
                     STKAYTTQLVALYMIALDMGIKRGTITEEFYNDIISELKLIPEKVQKILYQHDDIKEIA
                     KEIKDNEHAFYIGRGLDYNLSLEGSLKIKEISYMHAEAFAAGELKHGTIALIEENTPVV
                     ATMTQTDLFEKSISNIKEVKSRGAHVIAITQEGNKEAEQVADKVIYIPRTNDILQSIIA
                     VVPHQLLAYYVAILKDRDVDKPRNLAKSVTVE"
     protocluster    7295..29871
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3661921:3664498]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      17295..19871
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="2"
     CDS             complement(8634..9311)
                     /locus_tag="ctg1_3311"
                     /transl_table=11
                     /translation="MLILLDTANIESIKNINDIYPLDGVTTNPTIISKEKKDFISILRK
                     IRNVIGEEKMLHVQVIGSKAEDMIEEAVYLNEKIGGNLYIKIPVNEQGIKAMKKLSKEG
                     YKITATAIFTAQQALMAAKAGAEFVAPYVNRIDNLMGDGIKVVSDIVNIFETYNINSKV
                     LAASFKNTEQIHNACLKGAHSVTVNEDLIKQLIYHPLTDLSVDNFVKDWENQYGKNTKT
                     NEV"
     CDS             complement(9330..9977)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3312"
                     /sec_met_domain="HAD_2 (E-value: 6.1e-44, bitscore: 147.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDTIIFDMDGVIIDTEPLSFETSKILLKMYDKDYTEDFHNACMG
                     LSMIEVIRRTISNYDLEEDEDELLKRRNEIYIKIALEKSEPINGLFELLDYIKELNIKC
                     AVATGSNRGIAEILLKKLGIIDYFQFILPGDEMEKSKPDPWSYLEAMKRLGSSSEETII
                     MEDSINGIKSAIAAGCKVIAINSIWEDKSTKEIISFEKDLKGAKNVISTLIK"
     CDS             complement(10001..10786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_fatty_acids: adh_short_C2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3313"
                     /sec_met_domain="adh_short_C2 (E-value: 2.8e-56, bitscore:
                     188.4, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNFKEKTVIITGGAQSLGEYIAYSFAEKGANIVIADINYEQANKV
                     SQNIINKYKVRSIAVKVDVCKEEEVKNLIKNTIDNFSKIDILICNAGVVYSTKVTELPK
                     EKWDNILNVNLTGYFLCAKEAAKEMVKRKQGVIIDINSKSGKKGSLHNCAYSASKFGAI
                     GLTQSLALDLAEDGIRVNAVCSGNLLDSPMWKNGLYEQYAKKLNIPKEKVRQAYIDKVP
                     LKRGCTYEDVSNLVLFLSSKEASYMTGQAVNVTGGQEMR"
     CDS             complement(10806..11171)
                     /locus_tag="ctg1_3314"
                     /transl_table=11
                     /translation="MKTIYNTEVNKLGIMVEEFYGEKMIILFKDNAPEELADYCVLHGR
                     NELNDEIQVGDIFKIDGEEYKVTAVGDEVHKNLRDLGHICVRFDGSTNAELPGSLYLED
                     KEIKEIKEGTVIEVERP"
     CDS             complement(11387..12391)
                     /locus_tag="ctg1_3315"
                     /transl_table=11
                     /translation="MAKYNAIKVSAGNGGFGGPLTIVPTEQRNKIVNITGGVISDVAKK
                     LEELTGCELVDGFKTKVSDDEIACVIIDCGGTLRCGLYPKKGIPTINLMPAGPSGPLAE
                     YIKADIYVSSVKVKNIELADSSQNSENVYEENQQKEEVKKPKYDTTKKITQQSDRGIMT
                     KIGMALGNFVGMLYQAGRDTIDTVIKTILPFMAFVCMLIGIILKSGIGDAFASVLSPLA
                     GSLPGLVLLSAICSFPLLSPFLGPGAVIAQVIGVLIGVEIGKGNIPPHLALPALFAINS
                     QAACDFIPVGLGLAEAEPETVEVGVPSVLYSRFLTGPTSVFIAWLASFGLYAK"
     CDS             complement(12404..12949)
                     /locus_tag="ctg1_3316"
                     /transl_table=11
                     /translation="MDFLTNLAKGFIGLFQEGGNTFVGMAKGIIPTLIMLLVAMNALIR
                     IVGEERIEKLAKKSAANPITRYLILPVIGTFFFCNPMTLSLGKFLPEKYKPSYYAAASY
                     SCHTMNGLFPHINPAELFVFLGIANGITQLGLSTTDLAVRYFLVGIVTNFLRGWITDFT
                     TSYVEKQQNVKLSTKISL"
     CDS             complement(12992..13387)
                     /locus_tag="ctg1_3317"
                     /transl_table=11
                     /translation="MFIKIVIVIGLAWLLQTVLGFLQFKNFNKNFKELRQKGRVVIGKN
                     RGRVKRGSVILIAIDDNCSILESRIMKGITILARFKPMEILNNQNLHSINPNILESLDQ
                     QAALAVQDGIKNYNEYYKTKEEIDSNL"
     CDS             complement(13401..14450)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3318"
                     /sec_met_domain="ADH_N (E-value: 7.6e-34, bitscore: 113.6,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.6e-28, bitscore:
                     97.0, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGKMKAVALHAIKDLRYEEVDIPTIGENDVLVRVKYVGICGSDM
                     PRAMVSGAYHYPTITGHEFSGEVVEIGNNVDDIKVGERIAVAPLIPCGECEFCKKGNFA
                     LCETYEFLGSRNDGGFAEYVRVPKENVLILPEDLDYETAAGIEPASISYQAMSKTGIKV
                     GDTVAVVGCGPIGQFAIQWAKIFGASKVIAVDVLEDKLNLAKELGADIIINSKECNAVE
                     KVLEITNGGVEAVVETAGMKITEEQSVLMCRKLGKVVFLGISHDELRFSEKTFDRIMRG
                     EITLQGSWNSYAAPFPGIAWRTTLDFMEKGQIVFKPMVSHKIKLEELPGYFHKMFNKEI
                     NYNKVLVEI"
     CDS             complement(14485..15456)
                     /locus_tag="ctg1_3319"
                     /transl_table=11
                     /translation="MKYDDRILYKVAQMYYIDNMTQSEIAKRLGQYRTTISRMLKKARE
                     EGIVTINIKNNFDGCFQLEDALEKNFNLKEAIVIPTDEDEVESIRLKKLGQAGSEFLKR
                     ILKDGDILGFAWGKSVGEVANTLKDCKNVSANIVPLVGGPPSDMDNKYHVNTIVSRVSD
                     EFKAKGHYFYAPAITAEKSTKEAIMNDSNFKGILELWDKVNKAIVGIGAPLKGNNLIWS
                     GYFGDEDIQLLKDVDAVGDICSRFFDINGNIVDEKVKDRIISVELEKLKKMKYSIAVAE
                     SSEKAWSILGALNGGFVNVLITNNETAETVLNLHEQFTKNKK"
     CDS             complement(15811..17160)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_IV"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_I"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_III"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3320"
                     /sec_met_domain="PGM_PMM_IV (E-value: 1.9e-15, bitscore:
                     54.5, seeds: 63, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_I (E-value: 9.1e-45, bitscore:
                     149.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_III (E-value: 2.2e-35, bitscore:
                     119.0, seeds: 437, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_II (E-value: 2.2e-17, bitscore:
                     61.3, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILV
                     GMDTRISGDMLESALVAGILSVGAEAICVGVIPTPAIAYLTRKYNADAGVVISASHNPV
                     EYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYIDF
                     AKSTIKGDLKGLKVALDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHP
                     EDLMEYVVKNNCHMGLAFDGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTI
                     VVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKNDYAIGGEQSGHIIFSDYNTTG
                     DGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDT
                     ITKNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK"
     CDS             complement(17295..17825)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3321"
                     /sec_met_domain="POR (E-value: 5.9e-36, bitscore: 121.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASQQIIFAGFGGQGILSMGKFLAYAGMDANMEVSWLPSYGPEMR
                     GGTANCSVVLSDTPVGSPIVTKPDTVVVMNRPSLDKFEDMVVPGGLIIIDSDLVDRMPK
                     RDDVKVIAIPAQSEADKISSKKIANMILLGALVKETGIVTMDEITASLKDHGKEKFFEL
                     NKEALKAGEEYVK"
     CDS             complement(17827..18576)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3322"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.3e-26, bitscore:
                     88.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIVYQPPKALMDVPTHYCPGCTHGVIHKLVGEVIDELGVLDKTI
                     GVAPVGCSVLAYNYFACDMFEAAHGRAPAVATGIKRANPDSVVFTYQGDGDLAAIGTAE
                     IVHIATRGENITTIFVNNCIYGMTGGQMAPTTLPGQVTETTPYGRDTSYAGFPIRVSEM
                     IATLTGACYVERVAVNTVPNILKAKKAIKKAFQNQIDKKGFSLVEVLSICPTNWGLTPQ
                     ESMEWLRENMIPYYPLGVKKDTTEEVK"
     CDS             complement(18576..19646)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3323"
                     /sec_met_domain="PFOR_II (E-value: 2e-21, bitscore: 73.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.1e-53, bitscore: 180.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEKVLMKGNEAIGEAAIQAGCECFFGYPITPQTEVAAYMSKKMP
                     KIGKTFVQAESEISAVNMVYGAAGTGIRCMTSSSSPGISLKSEGLSYIAAAELPCVIIN
                     IVRGGPGLGSIQPAQSDYFQATKASGHGDFNMPVFAPASIQEMVDLIQNAFDVADTYRT
                     PCMVMGDGMLGQMMEPVEFKERSSKELPAKDWAANGLHGRKEHNIINSLYLQPEILEQH
                     NIHLQNKYAKIKENEVRYELYNCDKECDLILVAYGTTSRICKNVVKMAKEEGITLGLIR
                     PITIWPFPFEAFEKTVDLTKHGYLSVEMSCGQMVYDVKLASNGRKPVDFYGRTGGMVPD
                     PSDILEKVKSIVGGAK"
     CDS             complement(19662..19871)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3324"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-09, bitscore: 36.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0022, bitscore: 16.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKVIFREERCKGCGHCIQVCPKKIISFSEKLNVKGYNAATIVDE
                     KKDDCIACASCARICPDCVITVEK"
     CDS             complement(19973..20635)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3325"
                     /sec_met_domain="CbiA (E-value: 1.4e-07, bitscore: 29.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRINIFTGHFGSGKTEIAINYAIKLAKEGKKVALVDIDIVNPYF
                     CSRSLKEEFDKLGIRVIASDSKLMNAELMVVPGEVMAVFNDKSYEVVMDIGGDDQGATV
                     LGQYNKYFNEEDYDMYFVVNNNRPLTSNEKETEDYIKSIEISSRLKVKYLISNTNLSYE
                     TTVDHILKGDEIVLELSKKTGLPYKYIVCRKDFVDDIEGKVHGEIFPIDIYMKPPWR"
     CDS             complement(20898..21968)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_fatty_acids: Butyrate_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3326"
                     /sec_met_domain="Butyrate_kinase (E-value: 5.1e-168,
                     bitscore: 555.8, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYKLLIINPGSTSTKIGVYEDENQILEETLRHSSQEIESYKTIF
                     DQFEFRKEVILNVLKEKNFDVNELDAIVGRGGLLKPIEGGTYRVNDVMIEDLKIGVQGQ
                     HASNLGGIIANEIGKNLNIPAFIVDPVVVDEMKDIARISGMPEIERKSIFHALNQKAVA
                     KRYAKENNKKYEELNLIVTHMGGGASVGTHEKGKVVDVNNALDGEGPFSPERAGGLPVG
                     DLVKLCYSGKYTYEEMKKKISGKGGVVAYLNTNDFREVEERAEKGDKDAKLIVDAFIFQ
                     IAKEIGKNAAVLCGKVDAILLTGGIAYSKAICEGIKGMVSFIAPVVRFPGEDELLALAQ
                     GGLRVLKGEEEAKEYK"
     CDS             complement(21997..22908)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3327"
                     /sec_met_domain="PTA_PTB (E-value: 1.4e-66, bitscore:
                     222.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKSFDEILQKAKSQERRTISVAVAQDKHVLEAIKDAKEQGLVNA
                     ILVGNLEKIKEIAKEIDMKLEDYEIIDENDNRKAALKAVEVVSSGKADMVMKGLIDTAN
                     FLRAVLNKEIGLRTGKIMSHIAVFEVKKLEKLLMITDSAFNMYPGLEEKIDIVKNAVTV
                     AHAIGIENPKVAPICAVEVVNPKMPATLDAATLSKMSDRGQIKGCTIDGPLALDNAISE
                     EAAAHKGIDSPVAGNANIFLMPNIEAGNVMYKTLTYAADCKNGGLLVGTSAPVVLTSRS
                     DSHESKLNAIALAALVASQLKK"
     CDS             complement(22901..23995)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_fatty_acids: Butyrate_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3328"
                     /sec_met_domain="Butyrate_kinase (E-value: 9.9e-137,
                     bitscore: 453.0, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGNDLILVINPGSTSTKIALFNKENPIITDNLFHSLEEINKYDS
                     IYEQKGMREKIIMKWLEEKGVDLNKLVAIVGRGGLLRPMPGGTYKVTKKMLEDLKIGYQ
                     GQHASNLGGVIAYDISKKLNIPSFIVDPVAVDEILDEARISGMPEIKRRSLVHALNIKA
                     VTRKVCKKIDKNFYNSSFVVAHLGGGISVCPIENGKILDVNNANEEGPFSPERTGSLPV
                     GDLIKIAYSSKYPYKELKKKIIGKGGLIAYLDTNDGRLVDRMIEEGNKKAELILEAMAY
                     QIAKEIGSMATVLNGNVDAIILTGGLAYNKRLTTWIKERVEFISPIELVPGEEEMLALV
                     EGAIRILNKEENAKIYEEEVCFND"
     CDS             complement(24096..25694)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3329"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.9e-07, bitscore:
                     26.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRINNLTLEIDEDLNLLKNKVCKKLNISSHYIKDLKILRESID
                     ARRNSIKFNYSVEVSCEDEKRLIKNLKDKNITFEDDEYEEKIVLGTKDMKERSVIVGMG
                     PAGMFAGLMLAKNGYRPIIIERGEAIEERSKTVEKFWNTGILNIESNVQFGEGGAGTFS
                     DGKLTTRIKDKRCSFILEEMVKAGAPKEIIYSGKPHIGTDILKNVVKNIRNTINSLGGE
                     IRFNSKLENVIIKDGKVNAIIVNKEEIPCENLILAIGHSSRDTYEMLYKNNIFMESKAF
                     AIGVRVEHLKEMIDKNQYGKYAGHPRLKAADYRLTYKTKNSNRAVYSFCMCPGGEVVAA
                     ASEEGLLVTNGMSYYSRNKDNSNSAIVVSVTPEDFEGNTPLKGMEFQRYYERLAYKLGG
                     ENYNAPVQLIEDFLKDKNSSKLGAVKPSYKPGYEFKDISECLPNYVIDSLKEGFSSFDN
                     RIKGFASNDAILTGIETRTSAPVRLTRNENLESISLKGLYPAGEGAGYAGGIISAAVDG
                     VKVAENIIKTYSSLN"
     CDS             complement(25696..26976)
                     /locus_tag="ctg1_3330"
                     /transl_table=11
                     /translation="MGKKSKTKNIIVKICCIIASFALWLYIFNIENPIKEQKITVPVNI
                     VNKESMNEMELALVPKEASTVTLIIKGNVKDIYSVKAEDFKVEADLNSFGLKKGENKIP
                     VKVKKSPSNIKIVNEENLWTKITLDKLKSKTVPVKIKVTGTPKEGYAALNPILKQETAT
                     IYGTETYINKVKEVVGNCNIEGKSSEIKTNISLQPKTYDGDIINEISVEPSKVYVEIHL
                     RRIKKVPINMKLSEDISNNKNIESITPLQNEVEISGEEGALQNIKYINTETINVNSIKI
                     GQENIESNLVLPKGVILVNDNNTVKFKVKFKVIEDKKEEEKNKDKEENKEDKIIEKKVT
                     KDINIMNEPKDKEVSLSEPSVTINMKGNKDVIDKINVNNINCYVDLKNVNLGENVVKVI
                     VDMEDNKIDYSSNLDSIKVTVKEKQEE"
     CDS             complement(26946..27794)
                     /locus_tag="ctg1_3331"
                     /transl_table=11
                     /translation="LEFLDIIVNSIKNISIYSILDISVVSYIFYKSYMLIKETRAEQLL
                     KGIILIIILIPISSFLHLTMLSWILTKTLTIGVLSFVIIFQPEIRRALEHIGRSAFTDK
                     HLLQDEEVMGKVIDSIIVAVDNLSKSRTGALIVIEQFTGLGEIINTGTKLDAVVSSALL
                     ENIFVVNTPLHDGATIIRNDRIISAGCFLPLTQNTDINKKLGTRHRAAIGISESSDSIT
                     IVVSEETGMISLAVNGQLTRGYDKEKLKDIMIKIIKKGFDEDSTFRGQVVEWAKKVKQK
                     I"
     CDS             28049..28582
                     /locus_tag="ctg1_3332"
                     /transl_table=11
                     /translation="MKKYFLLDVIIVLTIIIFSSSWNKSIAAFSYMHNYNIDNSEDVQV
                     VNYTNKKIYLTKDDIYLMAQIVQAESESEPFEGKIAVASVILNRTVASGFPKTVESVIR
                     QKNAFSCLNKNGSISKIPDQTSFQAVEEALKGKDPTNNALYFYNPKISTCNWMKNVSKN
                     NKKIIGNHVFFKAN"
     CDS             complement(28974..29876)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3333"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.8e-22, bitscore:
                     75.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFSILHFLGGDIMGKRYDIAIIGSGPAGLEAAINAKIRNKDIII
                     FGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFERINNVYAMGEY
                     FALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGY
                     NKEAEEEANFVSELASKLYYIPMYRSDYELSEKVEVINDKPIEIVGEQHVEKLILKDSE
                     IEADGIFVLKDSISPSQLVPGLEMEDEHIKVDRKMKTNISGCFAAGDCTGKPYQYIKSA
                     GEGQIAALSAVSYLDKQSS"
     CDS             complement(29903..30220)
                     /locus_tag="ctg1_3334"
                     /transl_table=11
                     /translation="MVKEINESIFGEEVLNSEIPVVVDFWATWCGPCKMLAPVVEEVSQ
                     ELGQKVKFVKVNVDENPVISTQYKIASIPTLMTFKAGKAVETLVGFRPKEAIKSAVEKH
                     I"
     CDS             complement(30329..31504)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3335"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.8e-17, bitscore:
                     59.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITIIKNGYVYSPKFLGKKDILIASSSIEGVYDSLDIPKEFGEIK
                     VIDAKENIVTPGFIDSHVHLIGGGGEGGFSTRTPEIQLSHIISSGITTVVGCLGTDGIC
                     RSMEALLAKAKGLEEEGITTYIYTGSYSIPVNNITGCSKSDIMLIDKVIGVGEIALSDH
                     RSSQPSYEDFVKICAEGRVGGLLANKAGIIHVHIGSGKKGIDYLFKVIKDTEIPASQII
                     PTHMGRSEDLFNQGIQYMKKGGVIDLTTSSDPDFLEEGEIKASSGLKRILDSGLDIERV
                     HFSSDGQGSLPRFNEKREYVGLGIGSVHSLYREFKDCVVKEKIKIEDALKVVTSNVADY
                     LMLNNKGYIEKEKDADIVILDKENLEILHVICKGKHLVEDGKVLKKGTFEG"
     CDS             complement(31579..32832)
                     /locus_tag="ctg1_3336"
                     /transl_table=11
                     /translation="MNNEAKSRKIYTKALDNFNNGNIDKALDLCEKSISIDLKNNSAIN
                     LKGLLYYLKGDLISCKNLWKMNYHTNKDTVSYKYLQDAKLDEQFLKKYANAITLIKNND
                     IEGAIDLLKQCEKTDFNRINVCNNLAMCYIKLGKYNNALEYYEKALSIDKNNDISINIK
                     KELYKKGLIKKHKGKKILIAILVISIISSISIYLFNKFNKTKNISEIKNNKITSKENKN
                     KSNIPKKEEAKKTETKKQEIKKEEKIDIQNLNNYIEKKNYIQLYNIYSNYKNKNLDVNS
                     KSVLVKAEKLLKEEGVEYFYNTAMVNTNNKKYKESNDLLLKAYSLGNVNYLYPHIIYLL
                     ATNYEALNNISEAIRYYEIYASSFMKNDYGDLALYKLATLNEKVDDAKSKNYAKKLSQI
                     YPQSMYNNSNIKRIINNN"
     CDS             complement(32860..33600)
                     /locus_tag="ctg1_3337"
                     /transl_table=11
                     /translation="MLKNKKIALILITLIIFSFSIGCTKENKSSVENTKQEEQKVEYNN
                     NDKEEKDKKNNTEAKNEEKKDEKEVSEKTNFSKVEKEEIVDKKFQGENNTEWKESEQKK
                     YSAIVEGKGNNGEEEGIGKVYLKENNTNKLWLLKINEIKDQKSPKFLYWIDDENLLVII
                     GHGYGTVSKGGNLYCINVKNDTITPVYEAKDNKHEVISAEKVKDNSGKTSLILTLNVYE
                     DDNFIKSHKEKITISNDKVKEFIK"
ORIGIN
        1 ttacaaagga tcttctctct tttacatcgt aagctctatt caaccctctt actacagctc
       61 tgaaaccagc tgaagcagtc caaatagtaa atattatact gaaggaaagt aaatttccat
      121 tttgagtata aataatttct tctatagtat ttttcaataa taaataagta ttgcttggca
      181 ttatctcctt taatcccaat aatagatctt cactatgtat aggtaaatat cctattaatg
      241 ttattacaaa cattaggaaa ggaaatactg atataatcaa agcataggcc aactgtgagg
      301 ataatgctaa tacttcatcc tctagaaacc tatttgctag tttttttata ctcttaggta
      361 tgattttaga aagattttta ttcaaagcac taactccttt tagtattttt aatacaatta
      421 tatactatat aaagtaatat tagttagtat atttaaaaat taaagattta tttcaaaata
      481 gatgataaaa aataaaggac tagaaaatct aatcctttat ttttatactt ttatcatgag
      541 attattaaat tatacaacct atttggttgt tcaaaatttt tataaagtta tttttcataa
      601 ataagttatg atgtaaatcc tttgtaattt cttttaaggt atttataggc atacctatat
      661 cttcctctat aacttctaag aaatcatctt cttttgaaat tttttgtatt atttctttac
      721 cactagaata tatactaata tgaaatactc tagttttttc ttcccatttc ctattaaatt
      781 ctaagcaata cttttttaac tcttctatga gatgacattc atttaattca cataaattat
      841 atgctttatc aataaaatat tctatttcaa ctatagaatt ttcatttcta cataatgtct
      901 ttatttcccc tagaagttct tctttagaaa ctataggagt aactatttct tcattggtat
      961 tatttgtata acaaaagaaa actgtaggta taaatatata ttttacaaat cccaaaaggg
     1021 attccacatt tggatataca gcccaattat tatcaaaaat atttttttca taatctatta
     1081 tggtagtgtt aataaaaaga gattttggac ttattggtat atctttaaag tttccacccc
     1141 agacattctc tctctttaga agtaaatttt cccaatagaa aagatcatta tatttgttat
     1201 ccatatagca tacctcttat ataaagtttg tgtaaaaaaa tttttgtgtt acatataaat
     1261 tttatatggt ttttaaattg gtgtataaag ttatttttta agttgtatat tatttttaat
     1321 tgtgtataaa gttgtttccg agttgtgtgt catttttaat tgtgtataaa gtcgcttttg
     1381 agttatgtgt tatttttaat tgcgtataaa gttattttta agttgtgtat tatttttaat
     1441 attaatttgt tcttttctat ttagaatata attctactac tagagtttca tttgcgtcta
     1501 ttggtatttc atctctttca ggttctttaa ttaatactcc tgaaaattta tcataatcct
     1561 tttctatata tggtaggcta aattttttta aagctaagaa attatcagcg aactcatcat
     1621 tttttctata cttctccctt agagttatta catctcctgt ttttacttca taagatggta
     1681 tattaacttt gctaccatta actaatatat gtccatgatt caccatttgt ctagcctgtc
     1741 ttatagaatt agcaaagcct attctatatg ctatattgtc taacctacat tccagacttc
     1801 ttaataaaac gtctccagtt ctttctttac ttttcatagc ctttttaaca tatcttaaaa
     1861 attgcttttc tagaactcca taataagatc ttatcttttg tttctctaaa agttgtttac
     1921 cataatttga tagtttttta ccttccctac tgttttctct tgtggctctt ttcattgcct
     1981 tagggtgtcc ataaatattt actcctaacc ttctagataa cttaaatctt ggatctctta
     2041 tcttagccat ttcttcctcc taatactata ttcttagccg cgataatagt ttttctaaaa
     2101 actatttata ttataccaca aactgaaaat gattttcaat atccaattcg tattttttaa
     2161 atataaacct agtttttaag tagtataatc tattttatta tatatcctaa ctttcaacta
     2221 tctttaattc acatcatcta atggaaattt ttaaaccaat tcgctttagt ataattgcaa
     2281 tagacctata tgtatgatat aatttttgta aaattcaaac aatatcaaca tcatttgaaa
     2341 tctatattca tatctttcta aaatattgtc cttgtttcaa aaattgaatt ttaatattca
     2401 ctaatatcat atataattta aaaattaatt gcatattatt atataattag taattgtatt
     2461 aatcacttaa atatataaaa agggggagaa tatcaatgaa aaaattagga ttaataccca
     2521 aaattattat agccatcatt ttaggtattc taataggtag ctttacacca attcctgtaa
     2581 tacgcatatt tagaactttt agctccatat ttggagaatt tctaggattc cttatacctt
     2641 taataattct gggattcatt gttgccggta tcgctgaact tggacaaggt gctggtaagc
     2701 tattaggaat tactgttggt ttagcttatt tattcacact aatatctggt ttttctgctt
     2761 tattagttgg tagaacatta ttgccatcaa ttattactag tgccactcat gtagaaaaag
     2821 ctaaaaaagc tctggatcct ttctttgaag ttaaaattcc accaatgatg gacgttatga
     2881 ctgcacttat atttgctttt atattagggt taggtattgc aaagatacaa aataaaactc
     2941 taaaggatgt agctatagga ttccaagaaa taataacaaa agtcatcgaa aacgttgtta
     3001 taccactact tccacttcac atattaggca tattcgctaa cttagcttat actggtgaag
     3061 tatcaactgt tttaaaagta ttttggaagg tatttataat tatacttatt ttacattgga
     3121 ttatactaat tttccaattc tcagtaggtg gatctattgc tggtaaaaat ccttttaaat
     3181 cattaaaaat ccaaattaaa ggatatctta ccgctttagg aactcaatct tctgctgcaa
     3241 ctattcctat taatattcaa tgttcagaac aaataggaat tagcaaaggt ataagagatt
     3301 ttgttattcc tttatgtgca actgtccatt tatcaggaag tactattact ttaactatat
     3361 gtgcactatc tgttatgctg ttaaacggta tgcctataag tatgtctcag atggctggat
     3421 ttatagctat gctaggtgta actatggtag cagctcctgg tgttcctgga ggtgcagtaa
     3481 tggcagctct tggcatactt caatcaatat taggctttaa tgaggcttta cttggtttaa
     3541 tgattgctct atacattgct caagatagct ttggtactgc ctgtaatgta tctggggatc
     3601 aggccgtagc aatgattgtg gatgctatac aaaaaaaatc ggataaaaag cataataaaa
     3661 atatttaact aaacaattta tataaaatgg gtgtataaaa atttttactt ctatacaccc
     3721 attttgttag aataagagca attctagccc ttaaaaatac cttttataaa ttaaaataat
     3781 catgaaaaat tatgtataac aatatttaga taacacaagc tatggatttt atgcttatgt
     3841 tatttaatat gattttaaat tttattgcat atcttttcga agccaaattt ttctactaat
     3901 ttcttctcaa ctgcttcata taaactttct actttatttc ttaatttcaa gttataaata
     3961 taatttgttg taaagacaat tatatatgct cctataatat ctaaaggata atgatgttca
     4021 acatatactc ttgaaaatcc tacaataatg gaaaatacag ttaatattaa actaagtaat
     4081 ttattgtact ttctaagtcc taatgctata ctcattgtcc ctattgcatg gtcacttgga
     4141 agagatgaat tttttgtatg tatatataat aaatttacct tattatgaac aaaaggcctg
     4201 tccacataat atacgcctcc aataataaaa cttatagtta gattaattac tgcaataata
     4261 aaagtattaa aagcaacttt tctataatca caattctttt ttgtaattcc taaaataaat
     4321 actattgcaa ctatcgccat aaatatatag ggtatatcct ttgagaagaa aatcattatc
     4381 ttatctaaaa cactattttt atttgctaaa ttatttatta atcgaaaaaa ttccatattc
     4441 atattcatct atttctccta taatatattt tgtatatgtt tcttaataac gatcagaata
     4501 taattatcaa tatttatctt taataacata gcctacacct cttattgtag tataagattc
     4561 tctttagaat cattatcaat tttacttcgt aaacatctac tacattagta tctcctacat
     4621 aatcatagcc ccatacatct tcaattaatc gttctcttgt aagtacaata tttttattaa
     4681 ttaacagctt tttaagaaga tcatattctt tttttgtaag ttcaacttct ctgccagccc
     4741 tccaacttga tgtgttttat tatccatcac aatatctttt actttaattt catcaaattt
     4801 actttctact aacttttctc gttcatatac tcgtattctt gccaataatt cctctattgc
     4861 aaagggttta gttaaataat cattagcccc aacgtcaagt cctaaaactt tgtctgatac
     4921 atcacttttt gcagttaaca ttattatagg tacacaagaa aattgcctaa tccttctgca
     4981 aacttcaatc ccatttaaac ctggtatcat aatatcaaga agtattaact gatattctgt
     5041 attttccact ttctctaaag cccctcttcc gtcataagct atatcaactt tataatcttc
     5101 atgagtaagc tccatttcaa taaacattca catttgctct tcatcttcta ctaaaaggat
     5161 cttaaaattc ttcaaattac cacctcttct ataacaaaat agtgagccat taacccacta
     5221 tataatatac tagcttatac tattatataa tttccattgt ttattcctag tattactccc
     5281 ttataatatc tgagctcctt tatatttgta tgttatatat actaatttaa aaaacgttaa
     5341 aaattagatt aaaattaggt taaaattatg aattattaat aattcattac tttttatatt
     5401 tctcctgaaa attattatat ctcctattta taattttctt aataacttaa actattttgg
     5461 taaaatagga ataatcttta ccttaaaaat aaatgatata tataggaggt gttcatatgg
     5521 caaatttaac tcaaaaagaa caattacttt tacaagatca aaaaagtcat gaagaattgt
     5581 gcattaaaaa atatacaaat tacgcaaatc aatcaaagga tccacaacta aaacagatat
     5641 ttttaaacaa tgcacaggaa gaacaagaac atttaaacag cataaatcaa cttttaagtg
     5701 gtcaaattcc aaatgttaat tcacaacaaa ataatcagca acaaaataac caacaacaac
     5761 aaaattctca aatgcaatct aacactggaa ctggattagc aactacaaat gatgctgatc
     5821 tatgcaccga ccttttagct acagaaaaat atgtttcatc aacttatgat acagctatat
     5881 ttgaatttag agatcctaat attagaaatg ttttaaacca cattcaaaag gaagaacaac
     5941 aacatggaga agctatttat aaatatatgg aaagtaaagg aatgtataat cctcaataat
     6001 taaattatat acttatatga atgaaatcaa gcaaataaaa ttctattgtt ttacgctacg
     6061 tgaaggtcaa taatatatgt aaaacttatt tcataaaaaa agaaaaccag gaataatcct
     6121 gattttcttt ttatttttaa aatgttttct tatatttaaa cgaattttta tatagttaac
     6181 agtaatcgag ggacaaacca tactctattc aactgtaacg gatttagcta agtttcttgg
     6241 cttatctaca tcacggtctt ttagtattgc tacatagtat gctaataatt gatgaggcac
     6301 tactgcaata atactttgta atatatcatt tgttcttggt atataaatta ctttatccgc
     6361 tacttgctct gcttctttat ttccttcctg agttatagca ataacatgtg ctcctcttga
     6421 tttaacttct tttatattag aaatactctt ttcaaataaa tctgtttgag tcattgtagc
     6481 tactactggt gtattttctt caataagagc tatagttcca tgctttaatt caccagcagc
     6541 aaaagcttct gcatgcatat aagatatttc ttttatcttt aatgaacctt ctaatgaaag
     6601 attataatct aatcctcttc ctatataaaa tgcatgttca ttgtctttta tttcttttgc
     6661 tatttctttt atatcatcat gttgataaag tattttttgt actttttcag gtataagttt
     6721 taattcactt attatatcat tataaaattc ttcagttatt gttcctcttt ttatacccat
     6781 atctaatgcg atcatataca atgctacaag ttgagttgta tatgctttag ttgatgcaac
     6841 tgctacttca ggccccgccc aagtataaaa tacatcatct gcttctctag ctatagaaga
     6901 tcctacaaca ttagtaatag ctaaaactct cgctcctttt tcttttcctt ctcttacaac
     6961 tgctaaagta tctgctgttt ctccagattg acttacaaca ataattaatg ttttgtcgtc
     7021 tataaatgga tttctatatc taaactctga agctacatct gtttctacag ctatttttgc
     7081 aaatctttca atagcatatc ttcctgttat tcctgcattg tatgcagttc cacaagcaac
     7141 tatataaact ttatttattt catctaagtc ttcttttgtt agttttatat catctaattt
     7201 tattttacca ttttcatcta atcttctaac taaagtttct tttataccat ttggttgttc
     7261 atttatttct tttatcatga agtggtcata tccaccctta gatgctgctt ccacatccca
     7321 cattacatgg aaaggttctt ttgtgattcc ttcttccttt tcgttgtaaa tttttatttt
     7381 gtctttttct aaagtaacta cttctccatt atctaagaaa tatacatctc tagtatattt
     7441 taaaatagct ggtacatcag atgcaatgaa gttttcattc tctccaattc ctactattaa
     7501 tggactatct tttcttacag ctactaattg ttctgggtta tctttacaaa ctactcctag
     7561 agcataagct cctcttaatt tttttatagc cttaaatact gcttgtaata aatcaccttc
     7621 ataataatgg tcaactaaat gagctattac ttcagtatct gtttctgatt taaattttac
     7681 accttcagaa gacaaccagt cttttatttc catataattt tcaattatac cattgtgaac
     7741 tactgcaatt gtttcatcca tatttaaatg tggatgtgaa ttcacatcag atggcactcc
     7801 gtgagtagcc catcttgtat gacctattcc tatagttccc tccataggct tactttccaa
     7861 attttcactt aaaacattta gtctaccttt atatttttgg aactctattt cctttccatc
     7921 attaacagcg attcctgcag agtcatatcc tctatactct agttttgata atccatccac
     7981 gattacatcg cttgccttcc taaatcctac gtaacctact attccgcaca taaaaaaatc
     8041 ctccttagat tatattaata atttaagaag aaagtcctca ctaaagcttt tttgtaatca
     8101 gaatcacttc taacttttat tatagctttt agggctgtga gatcccatag gatatccgcc
     8161 gaaatttcga tactcctata tcctcgtcaa cttaagtgac actccaaatt ttcaatttgg
     8221 ttagtggaac ttactcagat gctaatctga gtttcctcta tatactccaa attttcaatt
     8281 tggccagtgg aacttactca gatgttaatc tgaatttcct ttataacccc aaattctcaa
     8341 cttgattagt cgaacttact cagatactaa tctgctataa gcacttaagt tctggcgctt
     8401 tcataacttt ttaactttct tcctaataca ttatagcatg ttcattttta tttgttaact
     8461 taatttttta tgaatattat attatatttt cattcaattt ttagttatat ttaatttttt
     8521 agtgaaaata tccctctaaa tttgctagta ttttttcata atattataat atgatgagaa
     8581 cacttaatat tgtacctata aattatacat tactattaaa atgctatttt gagctatacc
     8641 tcattagttt ttgtattctt tccatattga ttttcccaat ccttcacaaa attgtctaca
     8701 cttaaatctg ttaaagggtg atatattaat tgctttatta aatcttcatt tacagttaca
     8761 ctatgagctc cctttaaaca agcattatgg atttgttccg tatttttaaa actagcggct
     8821 aaaactttag aattaatatt ataagtttca aatatattta ctatatcaga aacaacttta
     8881 ataccatctc ccattagatt atctattctg tttacataag gagctacgaa ttctgctcct
     8941 gcttttgctg ccattaaagc ttgttgagct gtaaagattg ctgtagctgt gattttatat
     9001 ccttctttac taagtttttt catagctttt atgccttgct catttactgg tatttttata
     9061 tataaattac caccaatttt ttcatttaaa tatacagctt cttctatcat atcttctgct
     9121 ttagacccta ttacttgaac atgaagcatt ttttcttcac ctataacatt tcttattttc
     9181 cttaatatac ttataaaatc ctttttttct ttagatatta ttgtagggtt agttgtaacc
     9241 ccatctaatg gataaatatc atttatattc tttatagact ctatattagc tgtatctaaa
     9301 agtattaaca tgtaaatctt ccccctttgt tattttatca aagtgcttat tacattttta
     9361 gctcctttta aatccttttc aaaagatatt atttctttgg tgcttttatc ttcccatata
     9421 ctgtttattg caataacttt gcatcctgca gctatagctg actttattcc atttatagaa
     9481 tcttccataa taattgtttc ttcactagag gaacctaacc ttttcatagc ttctaaataa
     9541 gaccaaggat ctggttttga tttttccatt tcatctcctg gtaaaataaa ctgaaaataa
     9601 tctattatac ccaatttttt taacaatatc tccgctattc ctctattact acctgttgct
     9661 actgcacatt ttatatttaa ttcttttata taatctaata attcaaataa accatttata
     9721 ggttctgatt tttctaaggc aatctttata tatatttcat ttctcctttt taataactca
     9781 tcttcatctt cttctaggtc ataattgctt attgtccttc ttatcacctc aatcatacta
     9841 agccccatgc aagcgttatg gaaatcttca gtgtaatctt tatcatacat ttttaataaa
     9901 attttactag tttcaaagga taaaggttct gtgtctatta ttaccccatc catatcaaaa
     9961 attattgtat ctaacataat ttatctccta aaaatatatt ttatctcatt tcttgaccac
    10021 ccgtaacgtt tacagcctgt ccagtcatat atgaagcttc ttttgaactt aaaaataata
    10081 ctagattact tacatcctca taagtacagc ctctttttaa aggtacctta tctatatatg
    10141 cttgtctaac tttttcttta ggtatattta attttttagc atattgttca tataagccat
    10201 ttttccacat aggcgagtct aataaattac ctgaacaaac tgcattaact cttattccat
    10261 cctccgctaa atccaatgct aaactttgag ttaaacctat agctccaaat tttgatgcag
    10321 aataagcaca gttatgcaaa cttccttttt tacctgattt agaatttata tcgataataa
    10381 ctccttgttt tctcttcacc atctcctttg cagcctcttt tgcacataaa aaatatcctg
    10441 ttaaatttac atttaatata ttgtcccatt tttctttagg cagctcagta acctttgtac
    10501 tataaactac tccagcatta caaattaaaa tatctatttt actaaaatta tctattgtat
    10561 tttttataag atttttaact tcctcttctt tacaaacatc aactttaact gctatagatc
    10621 ttactttata tttgtttatt atattttgag atactttatt agcctgttca taatttatat
    10681 ctgcaattac tatattagca cctttttcag caaagctata agcaatatat tctcctaaac
    10741 tttgagctcc tcctgttatt ataacagttt tttctttaaa attcacagta tccctccttt
    10801 tctaactaag gtctttcaac ttctattaca gttccttctt ttatttcttt tatttcttta
    10861 tcttctaaat ataagcttcc tggtaattcc gcatttgtac ttccatcaaa tcttacacaa
    10921 atatgtccta aatcacgtaa attcttatga acctcatctc ctacagcagt cactttatat
    10981 tcttctccat caattttaaa gatatctcct acttgtattt catcatttaa ttcatttctc
    11041 ccatgaagta cacaataatc tgctaattcc tctggagcat tatctttaaa taagattatc
    11101 attttttctc cataaaattc ttctaccata attcctaatt tatttacctc tgtattatat
    11161 attgttttca taatatttcc tcctattttt aaactacttt tattaattta accttttata
    11221 ttattttaat tacatataaa gcaaataata taaattcaat tgtatattta aataacttaa
    11281 atatacaaaa ttattattat gcaaagtaaa aattaattta aattatttaa atataagaat
    11341 aaaagaatgc aatcctttta ttcttatatt ttatttttaa tcaaatctat ttagcatata
    11401 atccaaagct agcaagccat gcaataaata ctgatgttgg gcctgttaaa aatcttgaat
    11461 ataaaacaga tggtactcca acttctactg tttccggctc agcttctgca agtccaagac
    11521 ctactggtat aaagtcacat gctgcttgag agtttattgc aaataatgct ggtaatgcta
    11581 aatgtggtgg tatattacct ttaccaattt caacaccaat taaaacacct ataacttgag
    11641 ctataactgc accaggtcct aaaaatggtg acaataatgg gaatgagcat atagctgata
    11701 gtaatactaa tcctggtaag ctgcctgcca atggagataa tactgatgca aatgcatctc
    11761 ctataccaga ttttaatatt atacctatta gcatacatac aaatgccatg aatggtaata
    11821 tagtttttat gacagtatct atagtatcac ggccagcttg atatagcatt cctacgaaat
    11881 taccaagagc catacctatt ttagtcatta tacctctatc agattgttgg gttatctttt
    11941 tagttgtatc atatttaggt ttcttaactt cttctttttg ttgattttct tcataaacgt
    12001 tttcactatt ttgagaagaa tccgccaatt caatattctt aacctttaca gaagatacat
    12061 atatatctgc ttttatatat tcagctaatg gtccacttgg tcccgctggc attaagttta
    12121 tagttggtat acctttttta ggatataatc cacatcttaa tgtaccaccg caatctatta
    12181 ttacacaagc tatttcatca tctgatacct ttgttttaaa tccgtctacc aattcacagc
    12241 ctgtaagctc ttctaatttt tttgctacgt ctgaaataac tcctccagtt atattaacta
    12301 ttttatttct ttgctctgtc ggaactattg taagggggcc tccaaaaccg ccatttcctg
    12361 cactaacctt tattgcgtta tattttgcca tcaattacac ctcctaaagt gaaatttttg
    12421 tagataattt tacgttttgt tgtttttcta cataagaagt tgtgaaatct gttatccatc
    12481 ctctaaggaa atttgtaact ataccaacta agaaatatct aactgctaaa tccgttgttg
    12541 ataatcctaa ttgtgttata ccatttgcta tacctaagaa tacaaataat tctgctggat
    12601 ttatgtgtgg aaataaacca ttcattgtat gacaagaata tgatgccgct gcataataac
    12661 ttggtttata tttttctggt aaaaattttc ctaaagataa tgtcattggg ttgcagaaaa
    12721 agaatgttcc tattactggt aatattaaat atctagttat tggattagct gcactttttt
    12781 tagctaactt ttctattctt tcttctccaa ctattcttat taaagcattc atagcaacta
    12841 gaagcataat caatgtaggt attattcctt ttgccattcc tacaaaagta tttccacctt
    12901 cttgaaataa acctataaaa ccttttgcta aattagttaa aaaatccata aactcatctc
    12961 ctttttaata aaatattttt tattgactca attataaatt agaatcaatc tcctcctttg
    13021 ttttataata ttcattataa tttttgatcc catcttgtac tgccaaagct gcctgctggt
    13081 ctaaactttc caatatattg ggatttatgc tatggagatt ttgattattc aaaatctcca
    13141 taggcttaaa tctagctaaa atagtaattc ctttcatgat tctgctctca agtatagagc
    13201 aattatcatc aatagcaatc agtattactg aacccctctt tacacgtccc ctatttttcc
    13261 ctattactac tcttcctttt tgtctaagtt ctttaaaatt tttattaaaa tttttaaatt
    13321 gtaaaaaacc taatacagtt tgtagaagcc atgcaagtcc aataacaatt actattttta
    13381 taaacataaa ttcacctcta ctaaatttca accaatacct tattataatt aatttctttg
    13441 ttaaacattt tgtggaaata ccctggtaat tcttcaagtt tgattttatg agataccatt
    13501 ggtttaaata ctatttgtcc tttttccatg aaatctaatg tagttctcca agctattcct
    13561 gggaatggag ctgcatatga attccatgaa ccttgtaatg taatttctcc acgcattatt
    13621 ctatcaaaag ttttttcgct aaatcttaat tcatcatgtg atattcctaa gaatacaacc
    13681 tttccaagtt ttctacacat aagaacagat tgttcttctg taattttcat tcctgcagtt
    13741 tctacaacag cctctactcc accattggta atttctaata ctttttcaac tgcattacat
    13801 tctttactgt ttattatgat atctgcgcct aattctttag ctaagttaag tttatcctct
    13861 aaaacatcca cagctattac ctttgatgca ccaaatatct ttgcccattg aatagcaaat
    13921 tgtcctatag gaccacaacc aacaactgct acagtatcac caacttttat tcctgttttg
    13981 ctcattgctt ggtatgatat agatgctggt tctattcctg ctgctgtttc ataatctaaa
    14041 tcttctggaa gtattaatac gttttctttt ggaactctaa catattctgc aaaaccacca
    14101 tcatttctag aacctaaaaa ttcataagtt tcacataaag caaagtttcc ttttttacag
    14161 aattcacatt ctccacatgg tattaatggt gctactgcta ttctctctcc tacctttata
    14221 tcatctacat tattaccaat ttcaactact tctcctgaaa attcatgtcc tgttattgtt
    14281 ggataatgat atgctccact taccatagct cttggcatat ctgaaccaca tataccaaca
    14341 tatttaactc ttactaatac atcattttcg cctatagtag gtatatctac ttcctcatat
    14401 ctcaaatcct taattgcatg taaagctact gctttcattt ttccttccat tttataagac
    14461 tcccttcaaa gttttaaatt atatttattt tttattttta gtaaattgct catgtaagtt
    14521 tagtaccgtt tctgctgttt cattattagt tattaaaaca tttacaaagc cgccatttaa
    14581 agctcctaaa atagaccaag ctttttctga agattctgct acagctatag aatatttcat
    14641 tttttttaat ttttctaatt ctacacttat tattctatct tttaccttct catcaactat
    14701 gttgccattt atatcgaaaa atcttgaaca tatatctcct actgcatcaa catcttttaa
    14761 cagctgtatg tcttcgtctc caaagtatcc actccaaatt aagttattac ctttaagtgg
    14821 tgctccaatt cctacaatag ccttattaac tttatcccat aattcaagta ttcctttaaa
    14881 attgctatca ttcataattg cttcttttgt agacttctct gctgttattg ctggtgcata
    14941 aaagtaatgc ccttttgctt taaattcatc actaactcta gaaactattg tattaacatg
    15001 atatttatta tccatatcac taggtgggcc tcctactaaa ggtactatgt tagctgatac
    15061 atttttgcaa tctttcaatg tatttgctac ttctccaaca gattttcccc aagcaaagcc
    15121 taatatatca ccatctttta atattctttt taaaaattca cttcctgctt gacctaattt
    15181 tttaagtcta atactctcaa cttcatcttc atctgttggt ataactatgg cttcttttag
    15241 attaaagttt ttttctaggg catcctctaa ttggaaacaa ccatcgaagt tattttttat
    15301 atttatggta acgatgcctt cctctctagc ctttttcaac attctgctta tagttgttct
    15361 atattggccc aatcgttttg cgatttcaga ttgtgtcata ttatcaatat agtacatttg
    15421 tgcaacttta tataaaattc tatcatcata tttcatgagg cattttcaac ctttctcaat
    15481 tttatttgaa gactattaat caaattcccc ttgttatttt atctacaaat tttgcacatt
    15541 tgtgcaactg atgaaatttt gttttattgt tgtatttata atataacaat tttattgttt
    15601 tttcaacaat atataatctt tatttttttg aattatactc tatttattct atttttcttt
    15661 tattttttaa ataatttgta tgatttcatt attttttgaa tattttatta ttttaatttt
    15721 atttattata ataaaaaaca taagggtaat ttataattaa cctaataatt ataaattacc
    15781 cttatgtttt aaaaatataa attaatccta ttattttact ttattctcta ttaatttagc
    15841 taagccatgt gctaatttat caatttcctt ttggttttcc ccttcaagca ttactcttac
    15901 taaaggctct gtaccagaag gtcttataag cactcttcct gagccatcta aattttttgt
    15961 aattgtatct atttcagatt ttatttcttc atccttcaaa taaatatctt tttgatcatt
    16021 aggaacttta gcattaacta aaacttgtgg tagttctttc attatagaac atagttctga
    16081 aaaagtctta ccactttctt ttactatatg agctaattgt agagcagtta caagtccatc
    16141 ccctgtagtg ttataatctg agaatataat atgtcctgat tgttctccac ctattgcata
    16201 atcattttta agcatttctt ctaggacata tctatctcca acttttgttt ttatagtatt
    16261 tatttcttct tttttcatag ctatatctaa tccaagatta ctcattacag taactactat
    16321 tgtatttttc tttaatctac cttgtttttt taattcctta ccacaaatgg ctaatataaa
    16381 gtctccattt atcaaattac ctttttcatc tatggctaga catctatccg catctccatc
    16441 aaaagctaat cccatgtggc aattattttt aactacatac tccataagat cttctgggtg
    16501 tgttgagcca gagtttctat ttatatttat accatcaggt ttgttgttta taacatgaac
    16561 ttctgctcct aattctttaa aagcttctac agatgttata tatgatgctc cattagcaca
    16621 atctaaagct acttttaatc ctttcaaatc accctttata gttgatttag caaaatctat
    16681 gtaatctctt atagcctctc catcttcttc aatctttctt cctatatttt ctccagttaa
    16741 aactggaaca tccttaaaat catctcttat taatgcttgt atactatctt ctaattcatc
    16801 ggataatttg tatccatttt tattaaaaaa ctttatacca ttgtattcta ctggattatg
    16861 tgatgctgaa ataacaaccc ctgcatccgc attatacttt cttgttaagt aagctattgc
    16921 tggtgttggt attacaccta cacaaatagc ttctgctccc acagataata tacctgctac
    16981 taaagcactc tctagcatgt cccctgatat tcttgtatcc atacctacaa gtatcttaga
    17041 tctatgtgtt ccttctgtta atataaaagc tcctgcttta cctaatttat atgctaagtc
    17101 tgctgttaat tccttattag ctattcctct gactccatct gttccgaaca ttctacccat
    17161 gtaattcatc actcctattt tttaaataca catagatatt atattatagt ttactaattc
    17221 taacaatagg aaacataatt gaaaaatata aaaagccagt gaagatattt tctccactgg
    17281 caatatttaa tttattattt tacgtattct tctccagctt taagggcttc tttgtttaat
    17341 tcaaagaatt tttccttacc atgatctttt aatgatgctg ttatttcatc catagtaact
    17401 attcctgttt cttttacaag agctcctaaa agaatcatat tagctatctt tttactactt
    17461 attttgtctg cttcagattg agctggtata gctataactt ttacgtcatc tctttttggc
    17521 attctatcaa ctaagtcaga atctattatt attagtccac ctggaactac catatcttca
    17581 aatttatcta aagaaggtct attcattaca actactgtat ctggtttagt tactattggt
    17641 gatccaactg gtgtatcaga tagaactaca gaacagttag ctgtacctcc tctcatttct
    17701 ggtccataag atggtaacca tgaaacttcc atatttgcgt ccattcctgc ataagctaaa
    17761 aatttaccca ttgataatat accttggcct ccaaaacctg caaatataat ttgttgtgat
    17821 gccatattat ttcacctcct cagttgtatc cttcttaacg ccaagaggat agtatgggat
    17881 catattttcc cttaaccatt ccatagattc ttgaggagtt aatccccagt tagttgggca
    17941 tattgataat acttcaacta aagagaatcc ttttttatct atttgatttt ggaaagcttt
    18001 ctttattgct tttttagctt ttaatatatt tggaactgta tttacagcta ctctttctac
    18061 atagcaagcc ccggttaaag tagctatcat ttctgatact cttattggga atcctgcata
    18121 acttgtatct cttccataag gtgttgtttc tgttacttga cctggcaatg tagtaggcgc
    18181 catttgtcca cctgtcattc catatataca gttatttacg aatattgttg taatattttc
    18241 tcctctagtt gcaatgtgaa ctatttcagc tgtacctatt gcagctaggt ctccatctcc
    18301 ttgataagta aatactactg aatctggatt agctcttttt atacctgttg caactgctgg
    18361 tgctctacca tgagcagctt caaacatatc acaggcaaaa tagttatatg ctaaaactga
    18421 acatccaact ggagcaacac ctattgtttt atctaatact ccaagttcat caattacttc
    18481 tccaactaat ttatgaatta caccatgggt acatcctgga caataatgtg taggaacgtc
    18541 cattaatgct ttaggtggtt gatatactat agccattatt tagcacctcc tactatagat
    18601 ttaacttttt ctaggatatc tgatggatct ggaaccattc cacctgttct tccataaaaa
    18661 tctactggtt ttcttccatt agatgctaat ttcacatcat aaaccatttg tccgcaactc
    18721 atttctacgg atagatatcc atgtttagta aggtctacag ttttttcaaa tgcttcaaat
    18781 gggaaaggcc atattgttat aggtcttatt agccctaatg ttataccttc ttctttagcc
    18841 atttttacaa catttttgca tattcttgaa gttgttccat atgcaactaa tattaaatcg
    18901 cattctttat cacagttgta taactcatat ctaacttcat tttcttttat cttagcatat
    18961 ttattttgta aatgaatatt atgttgttct aatatttctg gttgtaaata taaggagttt
    19021 attatattat gctcttttct tccatgtaac ccattagccg cccaatcttt tgctggaagc
    19081 tctttagatg atctttcttt aaattcaaca ggttccatca tttgtccaag cataccatct
    19141 cccataacca tacaaggtgt cctgtatgta tcagctacat cgaaggcatt ttgtattaag
    19201 tcaaccattt cttgtataga agctggtgca aacactggca tattaaaatc accatgtcca
    19261 cttgcttttg tagcttggaa ataatctgat tgtgctggct gaatacttcc taatcctgga
    19321 cctcctctaa cgatgtttat tataacacat ggtagttctg ctgctgctat atatgaaagt
    19381 ccttctgatt ttaaacttat tcctggtgag cttgaagaag tcatacatct aattcctgtt
    19441 cctgctgcac catacaccat atttacagct gatatttcac tttcagcttg aacaaatgtc
    19501 tttcctattt taggcatttt ctttgacata taagctgcta cttctgtttg tggagtaatt
    19561 ggatatccaa agaaacattc acatcctgct tggatcgcag cttctcctat agcctcatta
    19621 cccttcatta aaactttttc acccattata acccctcctt cttacttttc tactgttatt
    19681 acacaatctg ggcatattct tgcacatgat gcacaagcta tacaatcatc tttcttttca
    19741 tcaactattg tagctgcatt atagcctttt acatttagtt tttctgaaaa gctaattatt
    19801 tttttagggc acacttggat gcagtggcca cagcctttac atctttcttc cctaaatatt
    19861 acttttggca ttataacccc tccttaagtt ttttaataag aatgccttac aagtctatat
    19921 tcagttttta tttattaata aattttaaga ttttgacaat tttaaattta aattatctcc
    19981 aaggcggttt catgtatata tctattggga atatttctcc atgaaccttg ccctctatgt
    20041 catctacaaa atcttttcta cacacaatat atttataagg aagaccagtc tttttagaaa
    20101 gttctaaaac tatctcatca ccttttaata tatgatctac tgtggtttca tatgaaagat
    20161 ttgtatttga tataagatat ttaactttta acctagatga aatttctata gattttatat
    20221 aatcctctgt ttctttttca ttagatgtaa gtggtctatt attattaact acaaaataca
    20281 tatcataatc ttcttcatta aaatatttgt tatattgacc aagcactgtt gccccttgat
    20341 cgtcaccacc tatatccata acaacttcat aacttttgtc attgaaaact gccataactt
    20401 caccaggcac aaccattagc tctgcattca taagtttaga gtcagaagct attactctta
    20461 tgcccaattt atcaaactct tcctttagac ttcttgagca gaaatatgga tttacaatat
    20521 ctatgtctac taaggctact tttttgcctt ctttagctaa ctttatagca taatttatgg
    20581 caatttctgt tttcccacta ccaaaatgtc ctgtgaaaat atttattcta ctcattttaa
    20641 tcactccaaa acagagcatt ttcataaaat gaaacccttt tcacatgtag taaaaaattt
    20701 ttcacactgt atgaaatagc tctttcattt ttcatcttta agtaaattta tagatgaatc
    20761 tgtaacttca ttatatcaca aaaatcacta tagttgtaaa gcaattttct atttttttta
    20821 attgttataa ttttatcata aaaaaaattc tttatttttc taattattct atttatatct
    20881 acattctaag attgacacta tttgtattct ttagcctctt cttctccttt tagtactctt
    20941 aacccacctt gagctaatgc taataactca tcttctcctg ggaatctaac tactggtgct
    21001 ataaaagata ccattccttt tataccctca catatagctt tactatatgc tattcctcct
    21061 gttaataata ttgcgtctac ttttccacat aaaacagcag cattttttcc tatttctttt
    21121 gctatttgaa atataaatgc atcaacaatt aattttgcat ctttatctcc tttttcagct
    21181 ctttcttcaa cttctctaaa atcatttgta tttaaatatg ctactactcc acctttaccg
    21241 cttatcttct ttttcatttc ttcataagtg tacttaccac tgtagcataa tttcactaga
    21301 tctcctactg gaagaccgcc tgctctttct ggtgaaaatg gtccttctcc atctaaagca
    21361 ttatttacat ctactacctt tcctttttcg tgagttccta cagaagcccc tccacccatg
    21421 tgtgtaacta ttaaattaag ctcctcatat tttttattgt tttcttttgc atatctttta
    21481 gcaactgcct tttgatttaa tgcatgaaat atactttttc tctctatttc aggcatacct
    21541 gatattcttg ctatatcctt catttcatca acaactacag gatctactat aaatgcaggt
    21601 atgttaagat tttttcctat ttcattagct attattcctc caagattaga tgcatgttgt
    21661 ccttgaaccc ctatttttaa atcttcaatc atgacgtcat ttactctgta agttccgcct
    21721 tcaataggtt ttaaaagtcc acctctgcct acaatagcat ctaattcatt tacatcaaag
    21781 tttttctctt ttaaaacatt taatataact tcttttctaa attcaaattg atcaaatata
    21841 gttttatagc tttcaatttc ttgtgaagaa tgtcttaatg tttcttccaa tatttgattc
    21901 tcatcttcat atacacctat tttagttgat gttgacccgg gattaattat taacaatttg
    21961 taacccattt taagttcctc cctaaattta agatatttat ttttttagtt ggctagcaac
    22021 taatgctgct aaagctattg catttagttt tgattcatga ctatcacttc ttgaagttaa
    22081 tacaactggt gctgatgttc ctactaataa tccaccattt ttacaatctg ctgcataagt
    22141 taatgtctta tacattacat ttcctgcttc tatgtttggc attaaaaata tattagcgtt
    22201 acctgctact gggctatcta tacctttatg agctgcagct tcttctgata tagcattatc
    22261 taaagctaac ggtccgtcaa ttgtacatcc ctttatttgt cctctatcac tcattttaga
    22321 aagtgtagcc gcatctagtg tagctggcat cttaggatta actacttcta ctgcacaaat
    22381 aggagcaact tttggatttt caataccaat tgcatgtgct accgtaactg catttttaac
    22441 tatatcaatt ttttcttcta accctggata catattaaaa gctgaatctg taatcattaa
    22501 taatttttct aattttttta cctcaaatac tgcaatatga gacattattt tgcctgttct
    22561 taatcctatt tctttgttta aaacagctct taaaaaattc gctgtatcta ttaaaccttt
    22621 cataaccata tctgcttttc ctgatgaaac tacttcaaca gcttttaggg cagccttcct
    22681 gttatcgttt tcatctatta tttcataatc ttctagtttc atatctattt cttttgctat
    22741 ttctttgatt ttttctaagt ttcctacaag tattgcattg acaagtccct gttccttagc
    22801 atcctttata gcttctaata catgtttatc ttgagcaacc gctacagata tagttcttct
    22861 ttcttggctc ttagcctttt gtagtatttc atcaaaactt ttaatcatta aaacacacct
    22921 cttcctcata aattttagca ttttcttctt tatttaaaat tcttattgcc ccttcaacta
    22981 aagctaacat ctcctcttct ccaggtacca attcaattgg agatataaac tcaactcttt
    23041 cttttatcca ggtagtcaat cttttattat aagctaggcc tcctgtaagg attatagcat
    23101 ctacattacc atttaatact gtggccatag aacctatttc ctttgcaatt tgatacgcca
    23161 tagcttctaa aataagttca gcttttttat taccttcctc aatcatccta tctacaagtc
    23221 ttccatcatt tgtatctagg tatgctatta gcccaccttt acctataatc tttttcttta
    23281 gttctttata aggatattta ctgctataag ctatttttat taaatctcct acaggtaaac
    23341 ttcctgtcct ttctggagaa aatggtcctt cttcattagc attatttaca tctaatattt
    23401 ttccattttc aattggacat actgatatac ctccacccaa gtgtgctact acaaaggaac
    23461 tattataaaa gtttttatca atcttcttac aaacttttct tgttacagcc tttatattta
    23521 aggcatgaac taaagacctt ctttttattt caggcatacc agatattcta gcttcatcta
    23581 atatttcgtc tactgctact ggatccacta taaacgaagg tatatttaat tttttagaaa
    23641 tatcataggc tataacccct ccaagattag aagcatgctg tccttgataa cctattttta
    23701 aatcttctag catttttttt gttaccttat aagtaccacc tggcataggg cgtagtaagc
    23761 cacctcttcc tactatagca acaagtttat ttaaatccac acccttctct tctagccatt
    23821 tcattattat tttttctctc ataccttttt gttcatatat tgaatcatat ttatttattt
    23881 cctctagtga atgaaataaa ttatctgtaa ttataggatt ttctttatta aataaagcaa
    23941 ttttagtaga tgtagatcct ggattaatta ctaatataag atcattacca ctcattttaa
    24001 atctcccata tttatattat tctttagctt atactattct ttaacttata ttttatcaaa
    24061 attcatgaac aacgcaatat tttttttaaa agtttttaat ttaacgaact atatgttttt
    24121 attatatttt cagcaacctt tactccatcc accgctgcag aaattatacc tcccgcatat
    24181 ccagcccctt ctcccgctgg atatagtccc ttcaaagata tactttctaa gttttcattt
    24241 ctagttaatc ttactggagc tgatgttcta gtttctattc ccgttaaaat agcatcattg
    24301 ctagcaaatc cttttattct attatcaaag ctagaaaaac cttcttttaa tgagtctatc
    24361 acataattag gtaaacattc cgatatatct ttaaattcat atcctggttt gtaggacggt
    24421 tttactgctc ctaatttaga tgaattttta tcctttaaaa aatcttctat caactgtact
    24481 ggagcattat aattttctcc acccaattta taagctagtc tttcatagta tctttggaac
    24541 tccattccct ttagaggtgt attcccttca aagtcttcag gtgttacaga tacaactata
    24601 gctgaatttg aattatcttt atttcttgaa taataactca taccattagt aactaacaaa
    24661 ccttcttcag aagctgccgc aactacctct ccaccagggc acatgcaaaa actatacact
    24721 gctctattac tatttttagt tttgtaagtt aatctataat ctgcagcttt aagtctagga
    24781 tgccctgcat atttcccata ttgattttta tctatcattt cttttaaatg ctctactcta
    24841 actcctatgg caaaagcctt actttccata aaaatattgt ttttataaag catttcataa
    24901 gtatctctag aactatgtcc tatagctaat attaaatttt cacaaggaat ctcttcttta
    24961 tttactataa tagcatttac ctttccatct ttaattatta cgttttctaa tttactatta
    25021 aatcttattt ctcctcccaa ggaatttata gtattcctta tatttttaac tacatttttt
    25081 aatatatctg ttccaatatg aggcttgcca gaatatatta tctccttggg cgctcctgct
    25141 ttaaccattt cttctaatat aaaagaacac cttttatcct ttattcttgt agtcaacttt
    25201 ccatcagaaa aagtacccgc tcccccttct ccaaattgta cattagattc tatatttaga
    25261 atccctgtgt tccaaaattt ctctacggtt ttacttcttt cttctatagc ttctcctctt
    25321 tctataatta taggcctgta tccattttta gctagcataa ggccagcaaa catgcctgcc
    25381 ggtcccatac ctactataac tgacctttct ttcatatctt tagttcccaa tactattttt
    25441 tcttcatatt catcatcttc aaaagttata tttttatctt ttaaattctt aattaatctt
    25501 ttctcatctt cacaagatac ttcaacagaa taattaaatt ttatagaatt tcttctagca
    25561 tctatagatt ctcttaatat ttttaaatcc tttatataat gtgaagatat atttaatttt
    25621 ttgcaaactt tattctttaa taaatttaag tcttcatcta tttctaaagt caaattatta
    25681 attctcaatg acatattatt cctcctgttt ttcctttact gttactttta tactgtctaa
    25741 attagaacta taatctattt tattatcttc catatctaca ataactttta ctacattttc
    25801 tcctaaatta acatttttta aatccacata acaatttata ttattcacat ttatcttgtc
    25861 tataacatct ttattgcctt tcatatttat agttacacta ggctcactta atgaaacttc
    25921 tttatcttta ggttcattca taatattaat atcttttgta actttcttct caattatttt
    25981 atcttcttta ttttcctctt tatctttatt tttttcttct tcctttttgt cttctataac
    26041 tttaaattta actttaaatt ttacagtatt attatcgttt actaatataa ctccttttgg
    26101 taataccaaa ttactttcta tattttcctg ccctattttt atagagttaa catttatagt
    26161 ttctgtattt atatatttta tattttgtag agccccttct tcaccagaaa tctcaacttc
    26221 attttgtaat ggtgttatag attctatatt tttattgttt gatatgtctt cactaagttt
    26281 catatttatc ggtacttttt taattcttct taaatgtatc tctacatata ctttggatgg
    26341 ctctactgaa atctcattta ttatatctcc atcatatgtt ttgggctgaa gagatatatt
    26401 agtttttatc tctgaagatt taccttctat gttacaattt cctactactt cttttacttt
    26461 gttaatataa gtttctgtac cataaatggt agccgtttct tgttttaaaa ttggatttaa
    26521 agctgcatat ccttctttag gagtacctgt tacttttatt ttaactggta ctgtcttaga
    26581 ctttagctta tccaaagtaa ttttagtcca taaattttct tcatttacta ttttaatgtt
    26641 actagggctt ttcttgactt taacaggtat tttattttcg ccttttttta agccaaaaga
    26701 attcaagtct gcctctactt taaaatcctc tgcttttaca gaataaatat cctttacatt
    26761 accttttatt atcaatgtaa cagtactagc ctcttttggc actaaagcta attccatttc
    26821 attcatactt tccttattta ctatgttaac gggaaccgtt attttttgct cttttattgg
    26881 attctctatg ttaaatatat ataaccacaa agcaaaagaa gctattatac aacaaatttt
    26941 gactattata ttttttgttt tacttttttt gcccattcta ccacctgccc cctaaaagta
    27001 ctgtcttcat caaaaccttt ttttattatt tttatcataa tgtcctttaa tttttcttta
    27061 tcatatcctc ttgttaattg accattaaca gctaaagaaa tcattcctgt ttcttcagac
    27121 actactatag ttatagaatc tgaactttct gatataccta tagcagccct atgtctcgtc
    27181 cctaattttt tatttatatc tgtattttgg gttagtggta gaaaacatcc tgctgatatt
    27241 attctatcat ttcttataat tgtagctcca tcatgtaatg gagtatttac aacgaatata
    27301 ttttctaata gagctgatga taccacagca tctaatttag ttcctgtatt tattatttct
    27361 cctaatccag taaattgttc aataactatt aatgctcctg ttctactttt tgaaagatta
    27421 tctactgcta ctataatgct gtctataact ttacccatta cttcttcatc ctgcaacaaa
    27481 tgtttgtccg taaatgcgct tcttcctata tgttcaagag cccttcgtat ctctggctga
    27541 aaaattataa cgaaggataa aacccctata gttaatgttt ttgttaatat ccaacttaac
    27601 atagttagat gtaaaaaact acttataggt attaatatta ttataagtat tatgcctttt
    27661 aacaattgtt ctgctctagt ctcttttatt agcatataac ttttataaaa aatataagat
    27721 actactgata tatctaatat agaatatata ctaatatttt ttatagaatt aactattata
    27781 tctaaaaatt ccaattataa gtcacccctt aaaataacta tatacctcaa ttatacacta
    27841 tttaattatt tttatatcat agttaaaata attttattat tttctttata ttttcttaag
    27901 tattaaaaaa taatttgtgg ttatactatt attagcctaa gttttttaaa acacggggaa
    27961 accaaatttt ggggtgaatc gtaaaattac gtaggttata ccttttccga acccgtcagc
    28021 taaccccgta ggcaaaagga gtgagaaaat gaaaaaatat tttttattgg atgtaattat
    28081 agttttaact ataattattt ttagttcatc ttggaataaa tccatagctg ctttttctta
    28141 tatgcataat tacaatattg ataactctga agatgttcag gttgtaaact atacaaataa
    28201 aaaaatatat cttacaaaag atgatatata cttaatggct caaatagttc aggctgaaag
    28261 tgaatctgaa ccctttgaag gtaaaatagc agtagcttct gtaattttga atagaactgt
    28321 agcatctgga tttcccaaaa ctgtagaaag tgttataaga caaaaaaatg ccttttcttg
    28381 cttaaataaa aatggatcaa tatctaaaat accagaccaa acaagctttc aggcagtaga
    28441 agaggcttta aaaggaaagg atcctacaaa taacgctctt tatttttata accctaaaat
    28501 atccacctgc aattggatga aaaacgtgtc taaaaataat aaaaaaataa taggtaatca
    28561 tgtatttttt aaagctaatt aaaaaattaa atacttcata tattataaaa aatcaaaagg
    28621 atttagcgca aaattcaaat tgtgtgctaa atcctatttt atttatttgt aaaatatact
    28681 tatatctaag ccagattgaa attttattta aaaataataa aaaaagccct attatttttg
    28741 tctatgaatt aattttatcc gatgactacc cgctctaata ctcccatcgc actctgtgaa
    28801 agcgattcgc accaaatcga agatttggac tctctgcttt tcttcaaagt gggagtaaag
    28861 agcggctacg tccctggata acgatttccc ctaaaggata acgacttcta aggagtagaa
    28921 ctcctaagaa ttctgttaat aagctttagt ggaagtaaaa gctccttcta aagctaagaa
    28981 ctctgtttat ctaaataaga aactgcgctt aatgctgcaa tttgaccttc tcctgcagat
    29041 tttatatatt gatatggttt accagtacaa tcccctgcag caaagcatcc tgatatgtta
    29101 gttttcattt tcctatcaac ctttatatgt tcatcttcca tttctaggcc cggtactaat
    29161 tgtgagggag atatactatc ttttaaaaca aaaataccat ctgcttctat ttctgaatct
    29221 ttaagaatta atttttccac atgttgttct cctactattt ctataggttt atcattaata
    29281 acttccactt tttcacttaa ttcataatct gatctgtaca taggaatata ataaagtttt
    29341 gatgctaatt cgcttacaaa attagcttct tcctcagctt ctttattata tcctattatg
    29401 gcaactgtct tatttttata aagtggtgca tcacaagtag cacaatatcc tacacctttc
    29461 cctaaaaact cctcttcacc ttttaatgct ttcccatact ctactccagt agctaatata
    29521 actgttttag cttcatacat tttttcatta accattagag caaaatattc tcccatagca
    29581 taaacattat ttattctctc aaaagttatt tctattccca tcttatctat atgatctata
    29641 aatttatctt ttagctcatt acctgaaata tcataaaaac caagataatt atttatttta
    29701 ggagccttca caagttttga acttaactcc ttattaccaa atattattat atccttattt
    29761 cttattttag catttatggc tgcttccaac cctgcaggtc cgctacctat tatagctata
    29821 tcatatcttt tccccataat atctcctcct aaaaaatgta aaattgagaa taacattaat
    29881 gctattctca atttatttta tattaaatat gcttttctac tgctgatttt atagcttctt
    29941 ttggtctaaa tccaactaat gtttctactg ctttccctgc tttaaatgtc ataagtgttg
    30001 gtatgctagc tattttatat tgtgttgata taaccggatt ctcatctaca ttaactttaa
    30061 caaattttac tttttgtcct aattcttgag atacttcttc cactacagga gcaagcattt
    30121 tacaaggtcc gcaccatgtt gcccaaaaat ctactactac agggatctct gaatttaata
    30181 cctcttcgcc aaatatgctt tcatttattt ctttaaccat aattaatcac cctccgatat
    30241 acccttatag ggtatgcatt tacttatatt ctaatatata caaatatatt agtcaatagt
    30301 tttaaaatgt attataaaaa tttattattt atccttcaaa tgtgcctttc tttaacactt
    30361 taccatcttc aactaagtgt ttacctttgc aaataacatg tagtatctct aaattctcct
    30421 tatctaatat tactatatct gcatcctttt ctttttctat atatccttta ttatttagca
    30481 tcaaataatc tgctacattt gatgtaacta cttttagtgc atcttctatt tttatttttt
    30541 cttttacaac acaatcctta aattccctat ataatgagtg tactgaacct atacctaaac
    30601 ctacatattc tcttttttcg ttaaatctgg gcaagcttcc ctgtccatct gaagaaaaat
    30661 gaactctttc tatatctaaa ccactatcta atattctttt aagtcctgaa ctagccttta
    30721 tttctccttc ttctaaaaaa tcagggtcag agcttgttgt taaatctata actccacctt
    30781 ttttcatata ttgtatccct tggttaaata aatcttcact tcttcccata tgagtaggta
    30841 taatttgaga tgcaggtatt tctgtatctt ttattacttt aaacaaataa tctattcctt
    30901 ttttaccact accaatgtga acatgaataa ttccagcctt attagctaat aatccgccta
    30961 ctcttccctc tgcgcaaatt tttacaaaat cctcataact aggttgggaa gatctatgat
    31021 ctgacaaagc tatttctcct acacctataa ctttatctat tagcataata tcagactttg
    31081 aacagcctgt gatattatta actggtatgc tatatgatcc agtgtatatg tatgtggtta
    31141 tgccctcttc ttctaatccc ttggctttag ctaacagagc ttccatactt ctacatatac
    31201 catctgttcc taaacatcct actacggtag ttataccaga acttattata tgtgataatt
    31261 gtatttcagg tgttctagtg ctaaatccac cttcaccacc accacctatt aaatgaacat
    31321 gggaatctat aaatcctggt gtaactatat tttccttagc atctataacc tttatttcac
    31381 cgaattcctt tggtatatct aaactatcat ataccccttc tatactacta gaagctatta
    31441 aaatgtcttt ttttcctaaa aatttagggg aatatacata tccatttttt ataattgtta
    31501 tcatctttat tctctcctgt aaaacaaaat tagaactaat attattgttt tacattataa
    31561 ataaaatatt ctaaaatatt aattgttatt tataattctc tttatattgg agttattata
    31621 catagactga ggatatattt gtgataattt tttagcataa ttcttagatt tagcatcatc
    31681 tactttttca tttaatgttg caagtttgta taatgctaag tctccataat catttttcat
    31741 aaaactacta gcatatattt cataatatct tatagcttcg cttatattat ttaatgcttc
    31801 ataatttgta gctaataaat atattatatg tgggtataaa taattcacat tacccaaact
    31861 atatgctttt aagagaagat cattactctc tttatacttt ttattattag tatttaccat
    31921 agcagtatta taaaaatatt ctacaccttc ttcttttaac agcttttctg cttttactaa
    31981 tacactttta ctattaacat ctaaattttt atttttataa tttgaatata tattgtatag
    32041 ttgaatgtaa tttttctttt ctatataatt atttaaattt tgtatatcta ttttttcttc
    32101 cttttttatt tcttgttttt ttgtctctgt tttttttgct tcttcttttt taggtatatt
    32161 ggacttattt ttattttctt ttgatgttat tttattgttt tttatttcac taatattttt
    32221 cgttttatta aatttattaa ataaatatat agaaattgaa gatataatgc taataactaa
    32281 tattgctatt aatatttttt tacctttgtg tttctttatt aagccctttt tatataattc
    32341 cttttttata tttatagata tatcattatt cttatctata gataaagctt tttcataata
    32401 ttctaaagca ttattatatt tacctaattt aatatagcac atagctaaat tattacatac
    32461 atttatacga ttaaaatctg ttttttcaca ttgctttaat aaatctatag ccccttctat
    32521 atcgttattt ttgattaatg taatagcatt tgcatatttt tttaaaaatt gttcgtctag
    32581 tttggcatcc tgtaaatatt tataagatac cgtatcttta tttgtatgat aattcatttt
    32641 ccataaattt ttacaactta ttaaatcacc ttttaaataa tacaataatc cctttaaatt
    32701 tatggcggaa ttattcttta aatctattga tatgcttttt tcacacaaat ctagggcttt
    32761 atctatattt ccattattaa aattgtctaa agccttagta tatatttttc tagatttagc
    32821 ttcattattc atctaaattt cctctcttag ctatagttct tatttaataa attcttttac
    32881 tttatcatta gaaatagtga ttttttcttt atgtgattta ataaaattgt catcttcata
    32941 tacatttaat gttaagatta agcttgtttt ccctgaatta tcctttacct tttctgcaga
    33001 tattacttca tgtttattat cttttgcttc gtatactgga gtaatagtat cattttttac
    33061 atttatacaa tataaatttc cacctttaga aactgttcca tagccatgcc caataataac
    33121 taataaattt tcatcatcta tccaatataa aaatttaggg cttttttgat cttttatttc
    33181 attgattttt aacaaccata atttattagt attgttttct tttaaataaa ctttacctat
    33241 tccttcctct tctccattat ttcctttgcc ttctacaata gctgagtatt ttttttgctc
    33301 actttctttc cattcagtat tattttcccc ttggaacttt ttatctacta tctcttcttt
    33361 ttctacttta gaaaaatttg ttttttctga aacttctttt tcatccttct tttcttcatt
    33421 tttagcttca gtattattct tcttatcttt ctcttcttta tcattattat tatattctac
    33481 cttttgttct tcttgcttag tattttcaac tgatgactta ttctccttag tacatcctat
    33541 tgaaaaacta aaaattatta aggtaattag tattagtgct atcttcttat tttttaacat
    33601 attatcccct ccaaaaatat agatatatct aattatatct aaaaatatca attgtgtaaa
    33661 aaaaactcca tgaaaacata aagttaacat gaagcttttt tattaagaat tcataattat
    33721 tttttttgct gttaaaatag aagatgcact catagaatac tcatctaatc catattctac
    33781 aagagtttct atagcatttt catccccagc catttctcca cacattccac accattttcc
    33841 ttctttatgt gctgcatcta tagtcatctt tattaatctt aatactgctg ggtgcattgg
    33901 atcataaaga tatgatattt tttcattcat tctatctgca gctaatgtat attgtattaa
    33961 atcattagta cctatactaa agaaatctac atatt
//
