LOCUS       NC_009495.1            27444 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_009495.1 Clostridium botulinum A str. ATCC 3502, complete
            sequence.
ACCESSION   NC_009495
VERSION     NC_009495.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:43:47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1362233
            Orig. end    :: 1389677
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..27444
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1372233:1379677]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..17444
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
     cand_cluster    1..27444
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /kind="single"
                     /product="Glycine_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..27444
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Glycine_reductase"
                     /region_number="5"
                     /rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /tool="gutsmash"
     CDS             2377..2685
                     /locus_tag="ctg1_1203"
                     /transl_table=11
                     /translation="MCKMITQDSEKVCIGENAIAINGAINIPKGEDREKFFKEFTKWLK
                     NNNCSFFGMTNYVKTEKEAKEKTKEILFDYASEELEKNLENFEDEENVIQLSKFKAL"
     CDS             3347..3550
                     /locus_tag="ctg1_1204"
                     /transl_table=11
                     /translation="MAIKNKLLDIRLSMGYKTQKEFAEFLGIRRVQYNKYENNKEQPAL
                     EALYKISLKLNIKMENIIYLDE"
     CDS             4337..4687
                     /locus_tag="ctg1_1205"
                     /transl_table=11
                     /translation="MLKKDTKDNINSVDEIQKNKAIFINYRRMKYMLTPQEFAQECELS
                     YQQVLQMCKNKEISALKTEGGHFKIPEKELDIFKNSGYVTKEEYLRVIRENEKLKTVIK
                     NCMNLLSATNNL"
     CDS             4971..5717
                     /locus_tag="ctg1_1206"
                     /transl_table=11
                     /translation="MNIKKLFFIFTLVVIVFATACTNKIKETNVRDTNEKPKEETKIID
                     SNGAEKAKLNLEFGAGKLNVDGNEEKLMKGKFIYSKKEWRPEIKYEVKDKEGEITISQP
                     SLNGGNISLNKKEYNEWDINLNEKIPMEIKLNLGAGEFKADLNKINLKELNVEMGVGKL
                     DLDISGNYKNNIKVDIQGGVGEATVYLSKSMGVKIKAEKGVGTINANGFIVEDGNIYKN
                     SQYGKSKNNIDVNIEAGVGAINIKEK"
     CDS             6036..6263
                     /locus_tag="ctg1_1207"
                     /transl_table=11
                     /translation="MIKVYTAEGCPWCTKAKTYLKTKGIAFQELNIEKDEKARDEMVQK
                     SSQRGVPVLDIDGSIIIGFNKPAIDEAINL"
     CDS             complement(6295..7755)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1208"
                     /sec_met_domain="Aldedh (E-value: 1.6e-164, bitscore:
                     545.5, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKNLYVENNLYKNFIGGQWVNSKTNNFIEISSPIDGSLVGKVPS
                     MSKEEVDLAIKNAKKAQSHWNEIPINEKATILLKAANILDEKAEEIADIMTKEIAKDKK
                     SSISEVRRTADYIRFSADTAKNMVGETLPGDSFPGNSKGKISIVNRVPLGVVLAISPFN
                     YPVNLSGSKIAPALMAGNSVVLKPATQGSISALHLVKVFEEAGLPSGVLNTITGKGSEI
                     GDYIVSHPMIDFINFTGSTEVGKRISHISVMKPMLMELGGKDAAIVLEDADLDLAAKNI
                     VSGAYSYSGQRCTAVKRILVLEEIADTLVEKVKERVESLKIGNPLKEQVDIVPLIDDKA
                     ADYVEALMEEANNKGATLLVGGKREGNLIYPTLFDNVTLDMRLAWEEPFAPILPIIRVK
                     DVDEAIRIANESEYGLQASIFTKEINKAFYVAEKLEVGTVQINNKPERGPDHFPFSGIK
                     ASGLGTQGIKYSIEAMSRPKAIVLNINL"
     CDS             complement(7795..8736)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1209"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.1e-45, bitscore:
                     152.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKNKNLDLMIIGAGPAGLSAAIYAARAKLNMILIENGIIGGQV
                     RSSYTVENYPGFKKIEGNRLADLMQEQATDLGATIDEFDMVEKIQLNNNEKIVETSEYI
                     YKPTVLIISTGATARKLPIPSEGKFSGKGIHYCAICDGAMYEGKTVGVIGGGNAALEEA
                     LFLTKFASKVYMIRRYDYFKGEKATLEEVENNSKIEILYNWDLVDVYGSNFIDKALIKN
                     VKTKEEKELKLDGVFGFIGSEPKTELFKEYISLTPKGYIKTNENMETNIKGVYAAGDVR
                     EKQFRQITTAVADGTIAALAAEKYIMEKTREK"
     CDS             9533..9910
                     /locus_tag="ctg1_1210"
                     /transl_table=11
                     /translation="MNNKVIMVTNNKLVSEKFNEKCQVEFILGDVNEVFNTVRDYVHKG
                     HELLTHPLMSSVKPNETPYRTVVISKYYKNVVDMESLNYIEESIHSLEKFQKSCGTPAW
                     NDNILKDFRLIDYDLIYNALN"
     CDS             10001..11287
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: Glycine_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1211"
                     /sec_met_domain="Glycine_reductase (E-value: 7.1e-218,
                     bitscore: 720.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLEIGKIFISDMQFSNETKVKDGVLYISKEELLKEIGTDERIKS
                     IDLEIAKPGDKTRIIPVKDVIEPRVKVEGNGGIFPGFISKVDTVGSGKTNVLKGAAVVT
                     TGKIVGFQEGIIDMSGEGAKYTPFSKTNNLVVVCEPKEGVNQYEHEEIVRTLGFKAATY
                     LGSLAKDITPDETKVYETLPLLEQVKKYPDLPKVVYVYMLQSQGLLHDTYVYGVDAKKI
                     IPTFIYPTEVFDGAIVSGNCVSACDKNPSYVHMNHPVIEDLYEKHGVEYNFLGCVITNE
                     NVYLADKVRSSSYTAKLVEFLGADAVIISEEGFGNPDADLVMNCNKISEKGIKTVLITD
                     EYAGQNGASQSLADSTPKGDAVVTGGNANEVVTLPPMEKIIGHVEVADVIAGGHVGSLK
                     EDGSIEAEIQVITGATSEVGFNYLSAKGY"
     CDS             11320..12363
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1212"
                     /sec_met_domain="GRDB (E-value: 1.2e-177, bitscore: 588.1,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVVHYINQFYAGIGGEDKADYKPEVREEPVGPGTQLNSLFKGE
                     AEIVATVICGDSYFNENIDEAKNTILEMIKKYDADLFIAGPAFNAGRYGVACGTIAKEV
                     EEKLNIKVLTAMYEENPGVDLYKKSLYILKTKKSAVGMRKALPVMAKLALKMGKGEEIG
                     LPEEEGYIERGIRKNYFSDERGSKRAVNLLVKKLKGEEFVTEFKMPVFDRVEPNKAVED
                     ISKCKIAIVTSGGIVPKGNPDHIESSSASKYGKYDIEGLMDLNSETHETAHGGYDPNYA
                     NEDSDRVIPVDVLRKMEKEGKIGSLHRYFYSTVGNGTAVASSKKFGNEIVNQLKEDGVD
                     AVILTST"
     CDS             12427..12621
                     /locus_tag="ctg1_1213"
                     /transl_table=11
                     /translation="VHMCTVVPISLTVGANRIVPTIAIPHPLGNPNLDKEREFELRYKL
                     VEKALKALETEIDEQKVFE"
     CDS             12772..13713
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1214"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.9e-51, bitscore:
                     171.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNVYDLIIIGSGPAGLSAGLYAARARLKTLILERNKAGGQIVIT
                     DEVANYPGSIRDATGASLVARMEEQVDEFGAERKKDNVKEVDFTGKIKIIKGEKEEYKA
                     KSVIIATGAAPRHIGCKGENELIGKGVSYCATCDADFFTDLEVFVIGGGDSALEEALYL
                     TKFARKVTVVHRRDALRGAKSIQEKVFKNPKIEIMWDSVVEEIKGDGIVESAVFKNKKT
                     GEITEYFADEDDGTFGIFVFVGYLPINNLFKDIVTINEAGYIKTNDRMETNIEGIFAAG
                     DIREKSLRQVVTAAADGAIAAVEAYKYVEDTF"
     CDS             13747..14067
                     /locus_tag="ctg1_1215"
                     /transl_table=11
                     /translation="MLVVDKKTFEDEVLKSDGYTLVDYFGDGCVPCEALMPDVEELSQK
                     YEDKVKFCKLNTSKARRLAISQKVLGLPTIILYKDGEKLEEVVKDDATKENIEAMIKKH
                     TL"
     CDS             14153..14284
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1216"
                     /sec_met_domain="GRDA (E-value: 1.6e-19, bitscore: 67.9,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFV"
     CDS             14306..14629
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1217"
                     /sec_met_domain="GRDA (E-value: 4.8e-49, bitscore: 163.6,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LENQKRVKTLTEKHGAENILVILGAAEGEAAGLAAETVTNGDPTF
                     AGPLSNVQLGLRVYHAVEPEFKEEVNEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCK
                     FLD"
     CDS             14724..16262
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1218"
                     /sec_met_domain="ACP_syn_III (E-value: 8.2e-09, bitscore:
                     33.0, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYPVIKGASYILVHTPDMVLHNGTTQTTEKVVNPDSEYLKELPK
                     HLRNFEDVLNYAPNQTYIGNMTPDQLGEIEMPWWDKKIEESSRFGKLGEMMPQDEFIGL
                     MEICDVFDLVVLEKSFVGDVKNKLEKHPLIDENMISKIKEGVAIEEIKKVVDEEGAEGL
                     YNEGTLVGCVKKAHDVDVNLSAHTMLENLVVKASGVLSLLNLIAKNNIDPNSIDYVIEC
                     SEEACGDMNQRGGGNFAKSLAEVAGFTNATGADMRGFCAGPSHSLIAASALVQSGVYDN
                     VVIAGGGASAKLGMNGKDHVKKEMPILEDCLGGFAVLVSKNDGINPILRTDLVGKHTVG
                     TGSSPQAVISSLVTDPLDKAGLKITDVDKYSVEMQNPDITKPAGAGDVPQANYKMIGAL
                     GVKKKHIEKKELKDFIQNHGMSGWAPTQGHIPSGVPYIGFARNDLTEGNLNRVMVVGKG
                     SLFLGRMTNLFDGVSIIIERNTGYKEEEKGISEDKVRKIIAESIKKLASQLVEE"
     CDS             16269..17444
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: FA_synthesis"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1219"
                     /sec_met_domain="FA_synthesis (E-value: 5.4e-70, bitscore:
                     233.7, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSMDNKEVNKIIGKTLLDIAESIEKGDFSRKIVVGITTLGSEHG
                     VENLVKGAEVAAKKHNDIKVVLIGPKVDTELEIVEANEEDKMYNKMEELLDTKYIDAAV
                     TMHYNFPIGVSTVGKVVTPADGKEMFLATTTGTASMNRTEAMIKNAVYGIITAKTMGIK
                     EPNVGILNLDGARQVEKALKELDKNGYKINFANSLRADGGSVMRGNDLLKGTPDVMVTD
                     TLTGNLLMKVFSSYTTGGSYEGFGYGYGPGIGEDYERNILILSRASGVPVVANAIEYAK
                     DLVKGNINKLIKEEFKKANEAKLKDILSSIENKEDKKIKDEEEVPMPTKEIATASISGI
                     DVMDIEDAQKTLWKEGIYAEGGMGCTGPVIKVNDKNYDKAAEILTEKGFIA"
     CDS             17871..18482
                     /locus_tag="ctg1_1220"
                     /transl_table=11
                     /translation="LRLTRDFYAKDARVLAKELLGKVLVREVDGIKLKGKIVETEAYIG
                     AIDKASHAYGGRRTKRTEPLYGKPGIAYVYFIYGKYFCFNIISKTEGEAEGVLIRALEP
                     LENINLISKLRFNKEFEELNNYQRKNITSGPSKLCMAFNINRDNNWEDLCESSSLYVED
                     VFYNDFEIIETVRVGIDYAEEARDFLWRYYIKDNAFVSVK"
     CDS             18548..20773
                     /locus_tag="ctg1_1221"
                     /transl_table=11
                     /translation="MGGSYNLYKIKDISCISKYCNCLQLVFEDLYDLKKYFNENKTLFC
                     NKALYVLINKIIISKIFMEKNNITGELAKKNIKYYALTLDTINLVNLVFDNVDKRFLES
                     IFKDNIKYEYINPSYYSLDKEDFLHYEDNIFYRYNIFLNKIIDEINGFDFIHSSCEIGE
                     IYEKIIAKEYKKSMGIFYTPEYIIDYILENVFYEFSPLENPFVKLIDISAGAGYFIIKA
                     YDKLKKVFTENIQNLQEKYKQNIYTIRKKGQSIKVTGEYYWQKENLHYHIINNCIYAAD
                     IDIYAIQITTINLLLKDTKSYVGKVNVANCDSLIRWEKDFNPTIKFLDNKYKYKTYKIK
                     NKGIEEAVNYKEKEVCNWKTYFKLYKFWRKKFDYIIGNPPWVSLSRKNKKACWKNSLEY
                     YIKNYGQCVHSPNLFEYFIKRALEKTKKDGYLAFVVPINFSRNSQYIQLRNEILNKYEI
                     KNLFFNIAFSGVITDGMVFILKKNKKCFNEIKIKVQGKDEYKIDKNELFSCNEYGFTFN
                     NNDFDEKIKNKILENSSFLSEISDTFTGFIGDCKNIYKENVDKSYIKIYKGKNIKKFIC
                     YSYFYYDFKDENIKGGTKDLKKLKYKGKILVRKTGNEIIAAYDEEGIIIEQSLYGIINL
                     KQNFSHKYILGILNSQLMSWYYKKYLITNKDSTPQLKKYRLNKIPIKNCNKNVQEEVEI
                     LSDKIFQALKNENVKEIDYYYKILNQKVFSIYGIDDIKIIRYIINDK"
     CDS             21209..22420
                     /locus_tag="ctg1_1222"
                     /transl_table=11
                     /translation="MAEYKPMDCESIIKYIKELNLDIFDEKMDLTAKEIGDGNLNLVFR
                     VKDNNTGKSVIIKQALPYLRVAGEGWKLTVDRNRIEAEAMMKQDKACPNSVPKIYYHDK
                     DYNLYVAEDLGSMDILRNGLMNMKKYPKFPDQIGKFLSRNLFYTSDLGLGAVAKKSLVS
                     KFINPELCDITEKLVLTDPYMNAESNDINPEIMDEVKDMWGRKDFRLEVTKLKNIFMTK
                     AEALLHGDLHTGSIFITEDDMRVFDTEFAFYGPYGYDIGLLFANFILNYISWEGREDRS
                     KEEIKEFRKYLLDTIEEIWHEFEIGLKEIWDKDCKEISSTVEGYKEYYINNLLQETIGF
                     SACEVMRRIIGMAHVPDLDVLKDLKQKAKAQRLGLKIGQEMVMRRNKITKIEDLSVFIS
                     QITK"
     CDS             22560..23609
                     /locus_tag="ctg1_1223"
                     /transl_table=11
                     /translation="MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKD
                     MIVRGAPAIGVTAAYGLYFAAKVAPEDKFENFFKYLKEKSSYLDSSRPTAVNLSWALKV
                     MESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGVGILTHCNAG
                     QLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNM
                     AAMVMSQGKIDAVIVGCDRIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINT
                     KTGEDIPIEERNPEEVTSRFGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFK
                     ENLKKLFEK"
     CDS             23633..23743
                     /locus_tag="ctg1_1224"
                     /transl_table=11
                     /translation="MVELLNIKNIKKSFSDVQVLHEINNLGILSPNLLIT"
     CDS             23760..24407
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1225"
                     /sec_met_domain="Aldolase_II (E-value: 1.6e-44, bitscore:
                     149.8, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPT
                     GVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMHLAVYNMREDVKAIVHAHPPASTAF
                     SVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHGALT
                     VGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG"
     CDS             24451..24591
                     /locus_tag="ctg1_1226"
                     /transl_table=11
                     /translation="MPVIEPLCLNFVKSGVMYKLYYNLMVFCFIINYKIKILGIGGKYE
                     T"
     CDS             24581..25375
                     /locus_tag="ctg1_1227"
                     /transl_table=11
                     /translation="MKLKPEIRREKILAEIEKNKTVDIMELSEKLQVSEMTIRRDLKRL
                     ESSEKLLRTYGGATRISEGECKKVIDDPLKGRVLKNKDEKAIIGKYAGELVENDDVIMI
                     DASTTALAICKYIRDKKVTVVTNSISVVTALASFDNITVVVACGILRHSSLSLVGSYVE
                     ESFKKFNIKKSFISAKALSFEAGLTDINAFEVETKKAAMSVSKEVIVLLDHSKLNNISL
                     LKVCETKEISKIIIDGLKEFTVEEEELLNKFKSNGIEVIIAK"
     CDS             25682..26041
                     /locus_tag="ctg1_1228"
                     /transl_table=11
                     /translation="MRNGFVFSLVMALIVAIFAIQNAVAIPIKILFWQINFSLAIIILF
                     SAVIGAVITGITGIKKERGIKKQNKDLLNKIEELEKTNVDLLDRLEKLSSDSKDEHYIK
                     DLEDKEIILDRENKK"
     CDS             complement(26395..27270)
                     /locus_tag="ctg1_1229"
                     /transl_table=11
                     /translation="MENEERLKIGNKVSNITIIVNIILSFIKVLFGIIGHSAATIADGI
                     HSLSDVLSTIAVIIGLKISSKPADKDHPYGHEKLEAVTSKLLATMLFLTALFIGYSGIK
                     VIINKDFSVPSKITIYVAILSIVTKEWMYRYTLKAAKKINSTALEADAWHHRSDSFSSI
                     GTLIGIVGARLKYPILDPIASLVICIFIIKVSIDIYKNSINQLVDHCADEKTINMITEQ
                     IKSIKEVERIDELKTRLHGSKLYVDVEIALDYSLSLKESHSIAEKVHDQIEASNNDIIH
                     CMVHVNPYEE"
ORIGIN
        1 cacatccaaa gagaaccata cctattacac acagtctata taaaaataga ctagttttac
       61 ttccttttaa aaattctatg tttgtttctc catagtagta atttcctatt acagaactaa
      121 aagcaaaaag gaatatacaa atggctataa aagtatttcc ccaggaacct acctgtgaac
      181 ttaatgcagt ttgtgtaagc tgaattcctg ttaagtcact ttttaaatag ctaccagaga
      241 ttaaaactat gaaagaagtt gcgctacata ttaatatagt atctgtaaat acacctaaag
      301 tttgaataag tccttgttta gcagggtgag taacattagc tgttgcagca gcatttggtg
      361 cgctccccat tccagcttca ttagaaaaca atcctctttt aatacccata agtatagcag
      421 ctcctaagct accaccaaca acctgtttta taccaaaagc attttctata ataagagaaa
      481 atatagtagg aatactgcct atatttttta aaataacgaa taaagctact actacataag
      541 ctattgccat tattggaaca ataatttcag ttgctctagc aattctttga acaccaccaa
      601 atataataag agaggtaagg accgctagta ttaatcctat aattaaagtg tttacaccaa
      661 aggcttgttc aaaagctaaa gagatagtgt tagcttgtac agagttaaat acaagaccgt
      721 aacttatagt tattaatata gaaaatatta ttcccatcca ttttttattt aaagcttttt
      781 ccatataata agcaggaccg cccctaaagc catgttcatc ttctacttta tatatttgtg
      841 ctaaagtgct ttcaacaaaa cttgaagcac caccgattag agctataagc cacatccaaa
      901 atacagcacc gggacctcca gaagcaatag ctatagccac accagctaag ttaccagtac
      961 caactcttga agctgtactt atacagaagg cttgaaaaga agaaactcct tttttctttt
     1021 tatgttcttc tctagcggat ttacttgcac cttcccctag taatctaaac atttctttaa
     1081 aatatctaat ttgaacaaat ttagatttaa aggagaagaa taaacctaaa gctattaata
     1141 atgctatcag tatataagac catagataat tgtttaatac tgatataaaa ttttctataa
     1201 aactcatata atttccacct ttccaaatat atttttatgt tattaaatta tttgctttat
     1261 ataaatacat ttaaaattgt atcagaaaat aatatgaata tcaatttaaa gtgtattctg
     1321 aaaaatgaac ttaaaaaatc aaaaaatgcc tcatttaaag gaaagcttta ttacaactaa
     1381 aatagtggaa aattttttat aaaattataa aaaatatata taatataaaa tatattctta
     1441 caaaatatat ttgcattaaa aattgcaaca gtattcaaaa tgttatttta aaataatttt
     1501 atatttataa tatgtttata tttaatgata ttaattataa acatattata aaagagtaaa
     1561 aaaatcccat atttttataa aagcatggga aataaataca attgtctgtg aaagaaaaac
     1621 ttcataaatt taaatttatt atgaaaaaaa ttatataatg ataacttaat tttttataat
     1681 taaaaatatg aaagttttca tttataaaat tcatactgaa tataggagga taatttaaaa
     1741 atattaaaaa tgatattatt aataaaactt tttaaataag agcttcttta taagtttttc
     1801 ttatttgatt tataaaaaaa tataatatat actagttttg ttggtaaata aaaatttacc
     1861 tagaggaact ttataatatt accccaaaaa actcaagaac tacagttata agcgaccctc
     1921 ttgttttaag gttttaaaat attatcttta aagccaaaag agaacttcat aacgtattta
     1981 aagtaaaaag aaacacaatc gtaattgtgt ttctttttac ttttttattt ttaaaaactc
     2041 ctacattgaa ttaaaggagt aaaggagagt tagtataata aggttagtat aaataaatac
     2101 aagggatttt tgcaagagaa ggaaaacctt ctaattatat attatgaata taaacatatt
     2161 attgatatat gtaatttgaa aaaccttgaa aaagtatgga aaagcgtata atttttaaaa
     2221 ataaagacta gtatacatta caaatttaat aatataaaaa tacagtgaaa aaatacggta
     2281 tattagactt tactataatt caatattatt gtaaaatgat gcaaataata aaaattcaac
     2341 acataaatta tatggaaatt tgaagggagt tagattatgt gtaagatgat aacccaagac
     2401 agcgagaaag tctgtattgg ggaaaatgct atagctataa atggagctat aaatatacct
     2461 aagggtgaag atagagaaaa attttttaag gaatttacaa aatggttaaa gaataataat
     2521 tgttcatttt ttggtatgac aaattatgtt aaaacagaaa aggaagcaaa ggaaaaaaca
     2581 aaagaaatat tatttgatta tgctagtgaa gagttagaaa aaaatttaga aaactttgag
     2641 gatgaagaaa atgtaataca attatctaaa tttaaagctt tataaaagtt gagatttctg
     2701 gcatttataa aatatttaaa taatccttag cttgtaattt taaaatagat tagtttatat
     2761 aaaaaataga attaatatat accttaatta tgaatataat ttttatttac ataatatagt
     2821 taagcatttc ataaaaacga atatttttat gaaatgtttt tttattgata tataaattaa
     2881 atattaaatg gagatgttct aaaatattta acacaactat gatacaaatt aaatatatct
     2941 tgggatatct cttgattaat aaagtatata gtaaattatt aatagcttct taaatataaa
     3001 agataaaaca gggggaatat tagtagacga tattttacca aaatcaaata actcttgaac
     3061 tacctcaata aaattttaat tgaataaagg aattttttaa catttatgga atattaaata
     3121 taatggtttt ctataagtta ctcatagacc tccatatgaa aaaagaactc cattttatta
     3181 ctggagttct ttttgtatgg aattttctat atattggtgt agtgttttgg tcatttttat
     3241 tatagccaga tataataatt ttattctttt ttaatataca tttttaaaca tataaaggaa
     3301 ataatattat accttagaat attatgtaat gggaggtatt agatatatgg ctataaaaaa
     3361 taaattgtta gatattagat taagtatggg ttacaaaacg caaaaggaat ttgctgagtt
     3421 tctaggtata agacgtgtcc aatataataa gtatgaaaac aataaagaac aaccagccct
     3481 agaagctcta tataaaatta gtttaaagtt aaatataaaa atggagaata ttatttactt
     3541 agatgaataa tattctttta ttttttatag taatagttca aaataatata ttttagttca
     3601 aaataggaaa tttttatacc aaagaagtat atagtattag taaagaaggg aaaaagaagg
     3661 agcaaaaagt gcctaaagtt aatgtacttt ttaagtaaac aagtaaggac atgaagctgt
     3721 atactactgt aaaagggcag ggagaacaaa gtgaatttct aaaaagagct ctagaatttt
     3781 acattaaata tttagaaaat agatttaaaa aatgatgcga aataaaaaaa taaagcctag
     3841 cagaaggcta gacttattcc aagttgctaa aagtgtgtta cgctacacta catttctagc
     3901 ttattcaaga ggaatgaaaa agttgtgtat tttaggtgca cttatacaaa tgttaatatt
     3961 tgatttacaa attaattaaa tattttgaat gatgtgcgtt gcaattacca tatctgcgct
     4021 gaaccaaaat aacccagaca ttattaaaaa ccttctttca ggtttacttg tttatttata
     4081 gtatctacca ataattaatt tttattcagg aggatttata aaaatttgtg ttatttattt
     4141 tggcactaaa gtagaagatc ttaagaagaa acaaagagtt aaattaatga tgatagtgat
     4201 ttaaaggcaa gaattagatg aatgaaccaa agggaataaa gataatcaac ctgaaataat
     4261 aggaactaga ataagttatg ttcagagtat acttaatgaa gttaataaat taaagaaaaa
     4321 tacagtatta gaacttatgc ttaaaaaaga tactaaagat aatattaatt cagtcgatga
     4381 aatacaaaag aacaaagcta tatttataaa ttataggagg atgaaatata tgttaacacc
     4441 tcaagaattt gctcaagaat gtgagttatc atatcaacaa gttctacaga tgtgtaaaaa
     4501 taaagaaatt agcgctttga aaactgaagg aggacatttt aaaatacctg aaaaagaatt
     4561 agatatattt aaaaatagtg gttatgtaac aaaggaagaa tatctaagag ttattagaga
     4621 gaatgaaaaa ttaaagacag ttattaaaaa ttgcatgaac ttattaagcg ctactaataa
     4681 cttataatat tgttaattta ctaaagcaac ataaataaaa actctagagg attaagcttt
     4741 ggagcttttt atttatgttt ttttattact tttagtacac aaaaaccgta ctaaaaaact
     4801 acggctttta tttaatttca gatgagaaac aaaaaaacgg gaatgcatat aatgaaaatg
     4861 agttatatca atacatgttg ggctatgtta attattgact atcttatgaa tatgatgata
     4921 aaatttttta tatagtaaat ataaatactg aattttaatg gggggataaa atgaatatta
     4981 aaaaactttt ttttatattt acattagtag ttatagtttt tgctacagca tgtacaaata
     5041 aaattaaaga aactaatgta agagatacaa atgaaaagcc taaagaagaa acaaaaatta
     5101 tagattctaa tggggcagaa aaagcaaaac ttaatttaga gtttggagca ggaaaattaa
     5161 atgtagatgg taatgaagaa aagcttatga agggtaaatt tatatatagt aaaaaggagt
     5221 ggagacctga aataaaatat gaagttaaag ataaagaagg agaaatcaca atttctcaac
     5281 cttcattaaa tggaggaaat atatctttaa ataaaaagga atataatgaa tgggatataa
     5341 atttaaatga aaaaatacct atggaaataa aattaaatct aggagcagga gaatttaaag
     5401 cagatttgaa taagataaac ttaaaagaat taaatgttga gatgggagta ggaaagctgg
     5461 acttggatat atcaggtaat tataaaaaca atattaaagt agatatacaa ggtggagttg
     5521 gtgaagcaac tgtatactta tctaaatcta tgggggttaa gataaaagct gaaaaagggg
     5581 taggtacaat taatgctaat ggatttatag tagaggatgg aaatatctat aaaaattctc
     5641 aatatggaaa aagtaaaaat aacatagatg ttaatattga agctggagtg ggagctatta
     5701 atataaaaga aaagtaaaaa aatatttaag ctaggtaaat tatatattta ctgttaagaa
     5761 aaataaatat agattaatat ttaatcaaat tttatgagat atagtaataa ggtcacttta
     5821 ttccattaat aagaaaaaat gattttatta ttataatata aaaagtaatt aatatgaaat
     5881 ataagttatg ctgtatttaa tatataaata aatatgaata aaattatata tataactaaa
     5941 cctatataca taaggagaat actgtgataa aatatagata taaagaagaa taattaaagt
     6001 tatataataa ttattattaa ataggatgtg attatatgat taaagtatat acagcagaag
     6061 gatgcccatg gtgcacaaaa gcaaagacat atttaaaaac aaaaggaata gcatttcagg
     6121 aactaaatat tgaaaaagat gagaaggcaa gagatgaaat ggttcaaaaa tcaagccaaa
     6181 gaggtgtacc tgtattagat atagacggat caattataat aggatttaat aaaccggcta
     6241 tagatgaagc tataaattta taaaataagg aagttgcgat gcaacttcct tattttataa
     6301 atttatattc agaactatag ctttaggtct agacatagct tctatggaat attttatacc
     6361 ttgagtacca agaccggagg ctttaatacc tgagaatggg aaatggtctg gtcctctttc
     6421 tggtttatta ttaatttgaa ctgtacctac ttctaacttt tctgctacat aaaaggcttt
     6481 atttatttct tttgtaaata tagaggcttg gagaccatat tcggattcat tagctattct
     6541 tatagcttca tctacatctt taactcttat tattggaagt attggagcaa agggttcctc
     6601 ccaagctaat ctcatatcta atgtaacatt atcaaataaa gtaggataaa ttaaattacc
     6661 ttctcttttt ccacctacta ataatgtagc ccctttatta ttagcttctt ccattaaagc
     6721 ttcaacgtaa tctgcagcct tatcatctat taaaggaaca atatctacct gttcttttaa
     6781 aggatttcca atttttagag attctactct ttcttttact ttttcaacta gtgtatctgc
     6841 tatttcctct aaaactagta ttctttttac agcagtacat ctttgaccag aataagagta
     6901 ggcaccagat actatatttt tagctgctaa atctagatcc gcatcttcta aaactatagc
     6961 agcatctttt cctcctaatt ccattagcat aggtttcata acagaaatat gggatattct
     7021 ttttcctacc tctgtgcttc cagtaaaatt tataaaatca atcataggat gagaaactat
     7081 ataatcacct atttcactac ctttacctgt aattgtattt aaaactccag aaggcagacc
     7141 agcctcttca aaaactttta ccaaatgaag agcacttatg ctaccctgag tagcaggttt
     7201 taaaactaca ctatttccag ccattaaagc tggagctatt ttagagccag ataagttaac
     7261 gggatagtta aagggagaaa tagctaaaac tacacctaag ggtactctat tgactataga
     7321 tattttccct ttggaatttc ctggaaaaga atctccaggt aatgtttctc ctaccatatt
     7381 ttttgcggta tctgcagaaa atcttatata atcagcagtt ctacggacct ctgaaataga
     7441 acttttttta tccttagcaa tttctttagt cattatatca gcgatttcct cagctttttc
     7501 atctaatata ttagcagctt ttaataggat agttgctttt tcgtttatag gtatttcatt
     7561 ccaatgggat tgagctttct tggcattttt tatagctaag tccacttcct ctttactcat
     7621 ggagggaact ttacctacca aagagccatc tataggagag cttatttcta taaagttatt
     7681 tgttttacta tttacccatt gtcctcctat aaaattttta tataaattgt tttctacgta
     7741 taaattttta aacatataga cacctctaat cttttctttt gtaatatata aatattattt
     7801 ttctcttgtt ttttccataa tatatttttc agcagctaat gcagcaatag ttccatcagc
     7861 tacagcagta gttatttggc gaaattgttt ttctctaaca tctccagcgg cataaacacc
     7921 ttttatattg gtttccatat tttcattagt tttaatatat cctttaggag ttaaagatat
     7981 atattcttta aataattctg ttttaggttc tgaacctata aatccaaaaa ccccatctaa
     8041 ttttaattct ttttcttctt ttgttttaac atttttaatt aaagctttat ctataaaatt
     8101 tgaaccataa acatctacta aatcccagtt gtataatatt tctattttag aattgttttc
     8161 aacttcttct agtgtggctt tttcaccttt aaaataatca tatcttctga tcatatatac
     8221 ttttgaagcg aatttggtta aaaacaaagc ttcttctaag gcggcatttc caccgccaat
     8281 tactccaaca gttttgcctt cgtacatagc accatcgcaa atagcacagt agtgtatacc
     8341 tttcccagaa aacttaccct cactagggat agggagcttt ctagctgtag cgccagtaga
     8401 tataattaag actgttggtt tgtatatata ttctgaagtt tcaactattt tttcgttatt
     8461 atttaattga attttttcta ccatatcaaa ttcatctata gtagcaccaa gatctgtagc
     8521 ttgctcttgc attaaatctg caagacggtt accttcaatt tttttaaatc caggataatt
     8581 ttcaacggta taactacttc taacttgacc accaattatt ccattttcaa ttaaaatcat
     8641 gttaagctta gctctagcag catatatagc agcagataat cctgcaggac ctgctcctat
     8701 aatcattaaa tctaagtttt tatttttttt attcatataa aatcacccct tattaccctt
     8761 atagggtata tattaattat actacttttt ttgtgtttca caatataatt aataaaaatt
     8821 attaataaaa aaatattatt ataaaaataa ataaaatatt attaataggt taaccattta
     8881 aaataaataa aattattata aaatgtaatt aattattaga gtttttaata taaataaaaa
     8941 aacaatataa atatagaaat aaaaagcata aatctgcata agatatcata gcttttatta
     9001 tagaaaaatt tattatcaat aaatttaata aaatttcata aaaatgatgt aataaatgat
     9061 gtaataaatg atgtaataat agaaaatttt tatatggaca taaaaaatct ataaggaata
     9121 cttatagtca ctatttggaa acaaaattca ctattttctg aaaagtatgt aaaataatat
     9181 tgaaatgagg tataatatag ttaaatattt aataaagttt ggatgaaatt ttcgggagat
     9241 taagttttag acttagctat gtagatttta aaataaatat taattctacg tggtatcctt
     9301 ataggatagc cgaaggaact aagtgttatt cccataaata acatgaatat ctcaggcaaa
     9361 tggaccgaaa attgacaaaa ctctggaaag cattacgcac cgaaggagca aaactctcag
     9421 gttaagatac agagataaaa gttatggact tttatctctg tttttttgtg caaataaaaa
     9481 ctttataatt tactaagaaa ttataaaaat aatggacagg gtggtgggct gaatgaataa
     9541 taaggttatt atggtaacta ataacaaact agttagtgaa aagtttaacg aaaaatgtca
     9601 agtagaattt atactaggtg atgtgaatga ggtttttaat acagtgagag attatgtaca
     9661 caaagggcat gaacttttaa ctcatccatt aatgagtagt gtaaagccta atgaaacacc
     9721 ctatagaact gtagttattt caaaatatta taaaaatgta gtggatatgg agtctttaaa
     9781 ttatatagaa gaatctatac attccttaga aaaatttcaa aaatcatgtg gtactcctgc
     9841 atggaatgat aatatcttaa aagattttag attgattgat tatgatctta tatataatgc
     9901 actaaattaa ttttatataa gatttatata aaaattgcta gaatcattta gcagtacaat
     9961 aaagataagg cattaaaaat ttaatttggg ggttgatatt atgcgtttag aaattggaaa
    10021 aatatttata agtgatatgc agttttccaa tgaaacaaaa gttaaagatg gagtcttgta
    10081 tatttctaaa gaagaacttc taaaagaaat tggtaccgac gagagaatta aaagtattga
    10141 tttagaaata gctaagccag gagataaaac tagaattatt ccagtaaaag atgtaataga
    10201 gccaagagtt aaagtagaag gaaatggtgg tattttccca ggctttataa gtaaagttga
    10261 tactgttggt tcaggcaaaa ctaatgtatt aaagggagcc gcagtagtaa ccacaggtaa
    10321 aatagtaggg ttccaagaag gtattattga tatgagtggg gaaggagcta aatatacacc
    10381 tttttcaaaa actaataatt tagttgtagt atgtgaacct aaagaaggag taaatcaata
    10441 cgaacatgaa gaaattgtaa gaactttagg gtttaaagct gctacttatt taggtagtct
    10501 tgcaaaagat attacaccag atgaaactaa ggtttatgaa acattacctt tattagaaca
    10561 agtaaagaaa tatccagacc ttcctaaggt agtatatgtt tatatgcttc aaagccaagg
    10621 acttttacat gatacctatg tatatggagt agatgctaaa aaaataatac caacatttat
    10681 atatccaaca gaagtatttg atggtgccat agttagtgga aattgtgttt cagcttgtga
    10741 caagaatcca agttatgtac acatgaacca tcctgttatt gaagatttat atgagaaaca
    10801 tggagtagaa tataattttt taggttgtgt tataacaaat gaaaacgttt atttggcgga
    10861 taaagttaga tcttcaagtt atacagctaa gttagtagaa tttttaggag cagatgcagt
    10921 aataatttca gaggaaggtt ttggaaatcc agatgcagac cttgttatga attgtaataa
    10981 gataagtgag aaaggtataa aaacagtatt aataacagat gagtatgcag gacaaaatgg
    11041 agcttcacaa tccttagcag attctacacc aaagggtgat gcagtagtta caggaggaaa
    11101 tgctaatgag gttgtaacat taccaccaat ggaaaaaatt attggtcatg ttgaggtagc
    11161 agatgtaatt gcaggtggac atgttggttc tttaaaagaa gatggttcta tagaggcaga
    11221 gattcaagtt attacaggag ctactagtga agttggcttt aactatttaa gtgctaaagg
    11281 ctattaaatt gtagttatat aatcaagggg ggaaaataaa tgattaaagt agttcattat
    11341 ataaatcagt tttatgcggg tattggagga gaagacaaag cggattataa accagaagta
    11401 agagaggaac ctgtaggtcc aggaacacaa cttaattctt tatttaaagg tgaagctgaa
    11461 atagttgcta cggttatttg tggagattca tattttaatg aaaatataga tgaagctaaa
    11521 aacactattt tagaaatgat taaaaaatat gatgcggatt tgtttatagc aggacctgct
    11581 tttaatgccg gaagatacgg agtggcttgt ggaactattg caaaggaagt agaggaaaaa
    11641 ttaaatataa aggttttaac agctatgtat gaagaaaatc caggagtaga tttgtataaa
    11701 aaatctttat atattcttaa aaccaagaaa agtgcagtag gtatgagaaa agcattacct
    11761 gttatggcaa aacttgcatt aaaaatggga aaaggggaag agataggact tcctgaagaa
    11821 gaaggatata tagagagagg cataagaaaa aattacttta gtgatgaaag gggatctaaa
    11881 agagcagtaa atcttcttgt gaaaaaatta aaaggcgaag aatttgttac agagtttaaa
    11941 atgccggttt ttgatagggt agaacctaat aaagctgtag aggatatatc aaaatgtaaa
    12001 attgctattg taacttctgg tggaatagta ccaaagggaa atccagatca tatagaatcc
    12061 tctagtgcat caaaatatgg taaatatgat atagaaggac ttatggattt aaattcagaa
    12121 actcatgaaa ctgcacatgg aggatatgat cctaactatg caaatgaaga ttcagacaga
    12181 gttatacctg tagatgtatt aagaaaaatg gagaaggaag gaaaaatagg atctcttcat
    12241 agatatttct atagtactgt tggaaatggt acagcagtag catcttctaa aaagtttgga
    12301 aatgaaatag taaatcagtt aaaggaagat ggtgttgatg cagttatatt aacttccaca
    12361 tgaggaactt gtactcgttg cggtgcaaca ctagtaaaag aaatagaacg tggaggactt
    12421 ccggttgtgc atatgtgtac agtagttcca atttctctta cagttggtgc taatagaata
    12481 gttccgacta tagcaatacc tcatccactt ggaaatccaa atttagataa agaaagagaa
    12541 tttgaattaa gatataagct tgtagagaaa gcattaaagg cgttagaaac agaaatagat
    12601 gaacagaaag tttttgaata gaagttttaa taaaagtaat tttaagtaaa ttttatatag
    12661 ttcaaagacg atttaatagg tcttaaatag tttcacgtgt taattttatt taaataatta
    12721 gattggtaaa aatataattt ttaagtatta aattgtgggg gggagcaaga tatggacaat
    12781 gtttatgatc ttataattat aggctctggt ccagcaggac tatcagcagg tttatatgct
    12841 gcaagagcta gattaaaaac tttaatatta gagagaaata aagcaggtgg acagatagta
    12901 ataacagatg aagtggctaa ttatccagga tctataagag atgctacagg agcaagttta
    12961 gtagctagaa tggaagaaca agtggatgaa tttggagcag aaagaaaaaa agataatgtt
    13021 aaagaggtag attttactgg caaaataaaa attataaagg gagaaaagga agagtataag
    13081 gcaaaatctg taattatagc tactggtgct gctcctaggc atataggctg caaaggtgaa
    13141 aatgaattaa taggaaaggg agtatcctat tgtgctactt gtgatgctga cttttttaca
    13201 gatttagaag tttttgtaat aggtggagga gattcagctt tagaagaagc cttatatctt
    13261 actaagtttg caagaaaggt aacagtagtt catagaagag atgctctaag aggagctaaa
    13321 tcaatacaag aaaaagtatt taaaaatcct aaaatagaaa ttatgtggga ttctgtagta
    13381 gaggaaataa aaggcgatgg aatagtagaa tctgcagtat ttaaaaataa aaaaacagga
    13441 gaaataactg aatactttgc agatgaagat gatggaactt ttggaatatt tgtttttgta
    13501 ggatatttac ctataaacaa tttatttaaa gatattgtta ctataaatga agcaggatat
    13561 ataaaaacta acgatagaat ggaaacaaat atagagggta tatttgctgc tggtgatata
    13621 agagaaaaat cattaagaca ggtagttact gcagcggcag atggtgctat agcagcagta
    13681 gaagcttata aatatgttga agatactttt taaatataaa aaatttattt gaaaggcggt
    13741 tataaaatgt tagtagttga taagaaaact tttgaagacg aggtattaaa atcagatggt
    13801 tatacgttag tagattattt tggggatggt tgtgttccat gtgaggcttt aatgcctgat
    13861 gtggaggaat tatcacaaaa atatgaagat aaggttaaat tctgcaaatt aaatacttct
    13921 aaggctagaa gacttgctat atctcaaaaa gttttagggc ttccaactat aatcttatat
    13981 aaggatggag aaaaattaga agaagtagtt aaagatgatg ctacaaaaga aaatatagaa
    14041 gctatgataa aaaaacacac actataaaat tttaaagatt atttagtcat ttaaagtgtg
    14101 tatataaata tcaaggaatt taaaatataa ataaattaag ggaggaattt taatgagtct
    14161 atttgaaggg aaaaaagtaa taataattgg agatagagat ggaataccag gtccagctat
    14221 agaaaaatgc atagaaggta caggcgctga agtagttttt tcatccacag aatgctttgt
    14281 ttgaactgcc gccggagcaa tggatttgga aaatcaaaaa agagtaaaaa cattaacaga
    14341 aaaacatggt gctgaaaata tattagtaat tttaggtgca gcagagggag aagcagcagg
    14401 tcttgctgcg gagacagtta ctaatggaga tccaactttt gcaggtccat tgtccaatgt
    14461 ccagttagga ctaagggttt atcatgcggt agaaccagaa tttaaagaag aagtgaatga
    14521 agaagtttat gaggaagaaa taggtatgat ggaaatggtt ttagaggtag atgaaattat
    14581 agaagagatg acagatataa gaacagagtt ttgtaaattc cttgattaaa acagggaaag
    14641 tagataaata aagaattata aaatttaaga ggctgtacta taggtttata atccagcctc
    14701 ctaaatatta ggggggaaaa gctatgaatt atccagtaat aaaaggagca tcatatattt
    14761 tggttcatac tccagatatg gtacttcata atggaactac tcaaactaca gagaaagtag
    14821 ttaatccaga ttctgaatat cttaaagaac ttcctaagca tttaagaaat tttgaagatg
    14881 ttttaaatta tgcacctaac caaacttata taggaaacat gacaccagat cagctaggtg
    14941 aaatagaaat gccttggtgg gataaaaaaa tagaagagag tagtagattt ggcaaattag
    15001 gcgaaatgat gcctcaagat gaatttatag gacttatgga aatatgtgat gtatttgatt
    15061 tagttgtatt agaaaaatcc tttgtagggg atgtaaaaaa taagttagaa aaacatccac
    15121 tcatagatga aaacatgatt tctaaaataa aagagggagt agctatagaa gaaatcaaaa
    15181 aagttgtaga tgaggaaggg gcagaaggct tatataatga aggtacatta gtaggttgcg
    15241 taaagaaagc tcatgatgtg gatgtgaatt taagtgctca tactatgcta gaaaatttgg
    15301 tggtaaaagc ttctggtgta ttatccttat taaatctcat agctaaaaat aacatagatc
    15361 ccaattccat agattatgtt atagaatgct ctgaagaagc gtgtggagac atgaatcaaa
    15421 gaggaggagg aaactttgca aaatctcttg cagaagtagc gggatttact aatgctacag
    15481 gagcggatat gagagggttt tgtgcaggac cgagccattc tctaatagct gcttcagctt
    15541 tagttcaatc cggagtatat gataatgtag ttatagctgg cggaggggca agcgctaagt
    15601 taggtatgaa tggaaaggac catgtaaaaa aagaaatgcc tatactagag gattgcttag
    15661 gtggatttgc tgtattagta agtaaaaatg atgggataaa tccaatactt agaacggatc
    15721 tagtaggaaa acatactgta ggaacaggat cctctccaca ggcagtaata agttctttag
    15781 ttacagatcc attagataaa gcaggattaa aaataactga tgtggataaa tattccgtag
    15841 aaatgcaaaa tccagatata acaaaaccgg caggagcagg ggatgtacca caagcaaact
    15901 ataaaatgat aggtgctcta ggagttaaga aaaaacatat agaaaagaaa gaattaaaag
    15961 attttataca aaatcatggt atgtcaggtt gggcaccaac gcaaggacat attccgtctg
    16021 gagtccctta tataggtttt gctagaaatg atttaacaga aggtaattta aatagggtta
    16081 tggtagtagg aaaaggtagt ttattcctag gacgtatgac aaatttattt gatggggtat
    16141 ctataattat agaaagaaat acaggatata aagaagagga aaaaggaatt tctgaggata
    16201 aagtgagaaa aataattgca gaatccataa aaaaattagc atcacagcta gtagaagaat
    16261 aaggggtgat gtatagtatg gataataaag aagtgaataa aataatagga aaaactcttc
    16321 ttgatattgc agaatctata gaaaagggag actttagtag aaagatagta gtaggaatta
    16381 ctactttagg tagtgaacat ggagttgaaa atttagtaaa aggtgctgaa gtggctgcta
    16441 aaaaacataa tgacataaag gtagttttaa taggacctaa agtggataca gaattagaaa
    16501 tagtagaagc taatgaagaa gataaaatgt ataacaaaat ggaagaatta ttagatacaa
    16561 aatatataga tgcagcagtt actatgcatt acaattttcc tataggggta tcaactgtag
    16621 gaaaggtagt taccccagct gatgggaaag agatgttttt agctacaact acaggaacag
    16681 cttctatgaa tagaacagaa gctatgatta aaaatgcagt atatggaata ataacagcta
    16741 aaactatggg gataaaagag cctaatgtag ggattttaaa tttagatgga gcaagacaag
    16801 tagagaaagc attaaaagaa ttagataaaa atggttataa aataaatttt gctaattctc
    16861 taagagcaga tggtggttca gtaatgagag gaaatgatct tttaaaagga acaccggatg
    16921 ttatggtgac agatactctt acaggaaatc ttttaatgaa agtattttct tcttatacta
    16981 ctggaggaag ttatgaagga tttggctatg gctacggacc aggtatagga gaggattatg
    17041 aaagaaatat cctaattcta tctagggctt caggtgtacc agtggtagct aatgctatag
    17101 aatatgcaaa ggatctagtt aaaggtaata taaataaatt aataaaagaa gagtttaaaa
    17161 aggctaatga ggctaaatta aaggatatat taagctctat agaaaacaaa gaagacaaaa
    17221 aaataaaaga tgaagaagaa gttccaatgc ctacaaagga aatagctaca gcatctatta
    17281 gtgggataga tgtaatggat atagaggatg ctcaaaaaac cctttggaaa gaaggtatat
    17341 atgcagaggg cggtatggga tgcacaggtc ctgtcataaa agtaaatgat aaaaattacg
    17401 ataaggctgc agaaatatta actgaaaaag gttttatagc ttaaaaataa actataaata
    17461 tatttgtgaa aattaaagtg aataagttta tttataaaat tttaaaggtg aatatggtat
    17521 taaaataaaa aagtccattt acatagttta agtaaagtat atttttaaaa agaaatttta
    17581 cttaaactag tagtggactt tttttatatt atttaaaagt attagtatat aaattaaatt
    17641 taatttggac atatgcagaa atactaaaga ttattcatat atttattagg tatattttct
    17701 tatatttact atattaaaat taaatctatt ttacacagat attttatata aaagtttgtt
    17761 ttaaaagtta gtataaagtt aataaccatg ataatataaa aatatatgat taaaatataa
    17821 atatatgaag aaaaatatta ttaaaatgtt gagtcctagg aggaataaaa ttgagattaa
    17881 caagagattt ttatgctaag gatgctagag tattagcaaa agaattatta gggaaagtat
    17941 tagttagaga agtagatggt attaaattga aggggaaaat agtagagaca gaagcttata
    18001 ttggggctat agataaagct tctcatgcct atggtggaag aagaactaaa agaacagaac
    18061 ctctttatgg gaaaccgggt atagcctatg tatattttat atatggtaag tatttttgtt
    18121 ttaatatcat aagtaaaaca gaaggagagg cagaaggggt ccttataaga gctctagaac
    18181 ctttagaaaa tataaatctt atatcaaaat taaggtttaa taaggaattt gaagaattaa
    18241 ataattatca aaggaaaaat ataacttcag gaccttcaaa gctttgtatg gcttttaata
    18301 ttaacagaga taataactgg gaagatttat gtgaaagttc tagcttgtat gtggaggatg
    18361 ttttttataa tgattttgaa attattgaaa cagtaagagt aggaatagat tatgcagagg
    18421 aagctagaga ttttttatgg agatattata taaaagataa tgcttttgtt tctgtaaagt
    18481 aacaagtact ttaaaatata aatatttaaa taaaatagct ttgtataagt gatatggggg
    18541 atgaaatatg gggggaagtt ataatttata taaaataaaa gacatatctt gcataagcaa
    18601 atattgtaat tgtttgcaat tggtatttga ggacttatac gatctgaaaa aatattttaa
    18661 tgaaaataaa actttatttt gtaataaagc tttatatgtg cttattaata aaataataat
    18721 ttcaaagata tttatggaga aaaataatat aacaggtgaa ttggctaaaa aaaatataaa
    18781 atattatgca ttaactttag atactataaa tcttgtaaat ttggtatttg ataatgttga
    18841 taagagattt ttagaatcta tctttaaaga taatataaaa tatgagtata taaatcctag
    18901 ttattatagt ttagataagg aagatttttt gcattatgag gataatatat tctatagata
    18961 caatatattt ttaaataaaa ttatagatga aataaatggg tttgatttta tacatagtag
    19021 ttgtgaaata ggagaaatat atgaaaaaat aatagctaag gaatataaaa aatctatggg
    19081 aatattttat acaccagaat atattattga ttacatattg gagaatgttt tttatgagtt
    19141 ttcaccactg gaaaaccctt ttgttaaatt aatagatata tccgcagggg caggatattt
    19201 tattattaaa gcttatgata agttgaaaaa agtttttaca gaaaatatac aaaatttgca
    19261 agaaaaatat aaacaaaata tttatactat tagaaaaaaa ggacaatcta ttaaagtaac
    19321 tggtgaatat tattggcaaa aagaaaactt gcactatcat ataattaata attgtatata
    19381 tgcagcagat atagatatat acgctatcca aataacaacc ataaatttac ttttaaagga
    19441 tacgaagtct tatgtaggca aggtaaacgt tgccaattgt gatagtctta taaggtggga
    19501 aaaagatttt aatcctacta ttaaattttt agataataaa tataaatata aaacctataa
    19561 aataaaaaat aaaggcattg aagaagctgt taattataaa gaaaaagagg tatgtaattg
    19621 gaaaacatac tttaaactgt ataaattttg gagaaaaaaa tttgattata ttataggcaa
    19681 tcctccgtgg gtttctttat ctagaaaaaa taaaaaagct tgttggaaaa attctttaga
    19741 gtattatatc aaaaattacg gtcagtgtgt acattctcct aatttatttg agtattttat
    19801 aaagagagct ttagaaaaaa caaagaaaga tggatattta gcctttgttg taccaataaa
    19861 ttttagtagg aattctcaat acatacaatt aagaaatgaa atattgaata aatatgagat
    19921 taaaaattta ttttttaata tagctttttc tggagttata acagatggaa tggtatttat
    19981 tttgaaaaag aataaaaaat gttttaatga aataaaaatt aaagtacaag gaaaagatga
    20041 gtataaaata gataaaaatg aacttttttc ctgtaatgag tatggattta catttaataa
    20101 taatgatttt gatgaaaaaa taaaaaataa aattttagaa aactctagtt ttttatcaga
    20161 aataagtgat acatttacag gatttatagg agactgtaaa aatatatata aagagaatgt
    20221 agacaagtct tatattaaaa tatataaagg aaaaaatata aaaaaattta tatgctattc
    20281 ctatttttat tatgatttta aagatgaaaa tattaaaggt ggaacaaaag atttaaaaaa
    20341 attaaaatat aaaggtaaaa tattagttag aaaaacagga aatgaaatta tagcagctta
    20401 tgatgaagaa ggtattataa tagaacagtc attatatgga ataattaatt taaaacaaaa
    20461 ctttagtcat aaatatatat taggtatttt aaattcccag ttaatgagtt ggtattacaa
    20521 aaagtactta ataacaaata aagattctac tccacaactg aagaaatata gattgaataa
    20581 aattcctata aaaaattgca ataaaaatgt tcaagaggaa gtagaaatat tatctgacaa
    20641 aattttccaa gctttaaaaa atgaaaatgt gaaggaaata gactattatt acaaaatatt
    20701 aaaccaaaaa gtgttcagta tttatggtat tgatgatata aaaataataa gatatataat
    20761 taatgataag taaagaaatg tataaatgta tataaaaata aggtttttct aattactatg
    20821 aaatatatat aaatgaaaaa acgttaattt tgaacaaagt aatatgttat tttgttcaaa
    20881 attaattttt tgtctaataa tagttttgca gattgaattt atgtaacaat agtgtttaaa
    20941 aatgaaataa aataacaaaa cataacaaaa atagtgaaaa atattgacga gtaaatgttt
    21001 gcaatggtat cattttcata taccttataa aataaagtta caagatacaa acaaaaatat
    21061 ccaaagatta cttaaaataa gatctcctct tttataaaat acaatataag gatcagtaat
    21121 ctttggatga tttttaagtt tcattaaaat atagattatt atgaatttaa tttaaattaa
    21181 tataaattat ttatgggggg gtatctatat ggcagaatat aagccaatgg attgtgagtc
    21241 aataataaaa tatattaaag agttaaatct agatatattt gatgaaaaga tggatttaac
    21301 tgcaaaagaa attggagatg ggaatttaaa tttagttttt agagttaaag ataataatac
    21361 agggaaatcc gtaattatta aacaagccct tccttattta agagtagctg gagaaggctg
    21421 gaagttaact gtagatagaa acagaattga agctgaagct atgatgaagc aggataaagc
    21481 ttgcccaaac agtgtgccta agatttacta tcatgataag gattacaacc tttatgtagc
    21541 agaagatttg ggaagtatgg acatacttag aaatgggtta atgaatatga aaaaatatcc
    21601 taagttccca gatcaaatag ggaaattcct atcaagaaat ctattttaca cttcagactt
    21661 aggattaggt gcagtagcta agaaatcttt agtttctaaa tttataaatc cagaactatg
    21721 cgatattaca gaaaaattag tgttaactga tccatatatg aatgcagaat caaatgatat
    21781 aaatcctgaa attatggatg aagttaaaga tatgtgggga agaaaagatt ttagattaga
    21841 ggttacaaaa ttaaaaaata tatttatgac aaaagcagaa gcactcctac atggtgatct
    21901 tcatacagga tctatattta taacagaaga tgatatgaga gtttttgata cagaattcgc
    21961 tttttatggt ccctatggat atgatatagg acttttgttt gcaaacttta ttttaaacta
    22021 tatctcttgg gagggcagag aagatagatc aaaggaagag ataaaagagt ttagaaaata
    22081 tttattagat accatagaag aaatttggca tgaatttgaa ataggtttaa aagaaatttg
    22141 ggacaaagat tgtaaagaaa tatcttcaac tgttgaagga tataaagaat attatataaa
    22201 taacttgctt caagaaacta taggttttag tgcttgtgaa gttatgagaa gaataattgg
    22261 aatggctcat gtaccagatt tagatgtttt aaaagattta aagcaaaagg ctaaagctca
    22321 aagattggga ctaaaaatag gacaagaaat ggtaatgaga agaaataaaa taacaaaaat
    22381 agaggatttg tcagtattta tttcacaaat aacaaaataa tttttaagat acttatttgg
    22441 attaaaagta tatagagtac ttaaaaacaa ctgttttata taataagatt ttcaaataaa
    22501 aaaggattag taaagaagaa ataaggtaaa taagataaaa gtaaagagga ggattaaaaa
    22561 tggcagagtt attagctata aaatgggatg ataatagaga taagttaata cttttagacc
    22621 aaacaatatt accaaataaa attgaatata tagaatacga tactgcagaa ggtgtatacg
    22681 attccataaa ggatatgata gttagaggag ctccggctat aggagttaca gcagcttatg
    22741 gtctatattt tgcagcaaaa gtagcaccag aagataaatt tgagaacttc tttaaatatc
    22801 taaaagaaaa atcatcatat ttagactcaa gtagaccaac agctgtaaat ttatcttggg
    22861 ccttaaaggt tatggaaagt aaagctttag aaaataaaga taaagatgtt aaagaaataa
    22921 agagtatatt aagagaagaa gcaaaaagaa ttcatgaaga agatatagaa atatgcaaaa
    22981 ctatagggga aaatcttata actttattaa aggatggagt gggaatatta actcattgta
    23041 atgctggaca acttgctaca tctaaatacg gaacagctac atctcctatg tatcttgcaa
    23101 aggaaaaggg ctggaatttt aaagtctatt cagatgaaac tagaccaagg cttcaaggat
    23161 ccactttaac ggctttagag ttatatgaag caggaataga tgtaactact ataacagata
    23221 atatggcagc tatggttatg tctcaaggta aaattgatgc ggtaatagta ggatgcgata
    23281 gaatagcagc taatggagat actgctaata aaataggaac catgggagtt tcaattttgg
    23341 ctaaatattt tggaatacca atgtatattg ctgcaccaac tccaagtata gatataaata
    23401 caaaaacagg agaagatata ccaatagaag aaagaaatcc agaagaagtt actagtagat
    23461 ttggtgtttg gacagcccca aaaggtgtaa aagtttataa tccaggattt gatgttacac
    23521 cacatgaaaa cataactgca attgttacag aaaagggtat agtatatcct ccttttaaag
    23581 aaaatttaaa gaaacttttt gaaaaataag aggttagaaa ggggctaaaa taatggtaga
    23641 acttcttaat ataaaaaata taaaaaagtc cttttcagat gttcaagtat tacatgaaat
    23701 aaataatttg gggattttat ccccaaattt attaatcact tagtaaagag ggtgacaatt
    23761 tgaataatga aacgtattta aggttacaaa ttgtagaggt aggaaaaaga cttcaacaaa
    23821 gattttttgt agcttcaaat gatggaaata taagtgctaa acttgatgaa aatactatat
    23881 tgattacgcc tacaggggtt aataaaggag aagtaacccc agatcaaata ataaaagtag
    23941 atagagaagg aaatgttata gaaggtcata tgaaggttac atctgaaata aaaatgcatt
    24001 tagctgttta taatatgaga gaagatgtaa aagctatagt tcatgcccat ccaccagcat
    24061 ccacagcttt ttcagtatca aaagaaaaac tagatgatcc tgttattctt ccagaagcag
    24121 ttttttcatt agggaaaata ggatattgtg aatatggaac tccttctact gatgaggttc
    24181 caaaagctat agaaaaagaa attccatata gtgatgtact tttattatct aaccatggag
    24241 ctcttacagt aggtacagat gtaatgcagg cttattacag aatggaaaat ttagaaatgg
    24301 tttcaaaggt aactatttat tcaaaaatga taggaaatat aaaaacttta aatgaactac
    24361 aagttgagaa attaaataaa gtaaaagaag aaaaaggttg ggggtaaatt atagttacca
    24421 cccatagagc tttttaataa ttaggtaaat atgcctgtaa tagaaccatt atgtttaaat
    24481 tttgtaaaaa gtggtgtcat gtacaagtta tactataact taatggtatt ttgttttata
    24541 attaattata aaataaaaat attaggaata ggtgggaaat atgaaactta aacctgaaat
    24601 tagaagagaa aagatattag cagaaataga aaaaaataaa actgtggata taatggaatt
    24661 aagtgaaaaa ttacaggtat cagaaatgac tataagaaga gacttaaaaa gattagaaag
    24721 cagtgaaaaa ttacttagaa cctatggagg agctactcgt atatctgaag gagaatgtaa
    24781 aaaggttata gatgatccct taaagggtag agtattaaaa aataaagatg aaaaggctat
    24841 tataggtaaa tatgcagggg aattagtaga aaatgatgat gttattatga tagatgctag
    24901 tactacagcc ttagcaatat gtaaatatat aagagataaa aaggtaacag tagttacaaa
    24961 ttctataagt gtagtaacag ccttagcttc ttttgataat ataacggtgg tagtagcctg
    25021 tggaatatta cgacatagtt ctttatcttt agtaggctcc tatgtagaag aatcttttaa
    25081 aaaatttaat ataaaaaaat cttttatatc agctaaggcc ttgtcctttg aagcaggact
    25141 tacagatata aatgcttttg aagtagaaac aaaaaaggct gctatgtctg taagtaaaga
    25201 ggttatagtt cttttagatc actctaaact taataatata tcccttttaa aggtttgtga
    25261 aacaaaagaa ataagtaaaa taataataga cggacttaag gagtttacag tggaagaaga
    25321 agaattatta aataaattta aatctaatgg tatagaagta ataatagcta aatgatgtag
    25381 atatattttt tagcatttat gtttgaaaaa gatatatgta ttttatctaa agataaagat
    25441 aagatgggaa cacatattaa gatatatatg cctatagata aaagatattt caaaaataag
    25501 tcttaaaaga ttaattatct aaaagtaaga aagaataata ctaagttcta aatttttaga
    25561 cttagtattg ttctttctta caatttaaat cctttaagtt tgcttaatat aagtaagttg
    25621 atagttatgt aaagattgtt gtatcatata gttattatat aaaataaagg gaggattatt
    25681 tatgagaaat ggatttgtat tttctcttgt aatggcactt attgtagcta tatttgctat
    25741 acaaaatgca gtggcgatac caataaaaat tttattttgg caaattaatt tttctttagc
    25801 aattataatc ttattttcag ctgttatagg agcagttatt acaggtatta cgggtataaa
    25861 aaaagagaga ggtataaaaa aacaaaataa agatctttta aacaaaatag aagagctaga
    25921 aaagactaat gtagatttat tagatagatt agaaaaatta agttcagatt ccaaagacga
    25981 acattacata aaagatctag aggataaaga aataatttta gacagagaaa ataaaaaata
    26041 attttataat atttatttag gataaaaaga gtatatctta gaatgaaata gatttaaatt
    26101 taggctacta gtataaaaaa gaagcttctt aagccaattt atttcgctaa gaagttttaa
    26161 attagagatt ctattaaaaa gtttttacct agctaaggct tatcttgcgg atccatgacc
    26221 agtcacctaa tgttttgtga ggtgactggt caatttttaa atatgccaga ttaagaacta
    26281 tgaaagctta ttcatatatt attacctata ttctttatct ttgctatatt aaaattaaag
    26341 acatattttt gacagctttc aaagttaaat aaggtatctt aagataaaac tttattattc
    26401 ttcataggga tttacatgaa ccatacaatg aataatatca ttgttgcttg cttctatttg
    26461 gtcatggacc ttttctgcta tgctatgaga ttcttttaaa gataagctat aatcaagagc
    26521 aatctctaca tctacataaa gtttgcttcc atgaagccta gtttttaatt catctattct
    26581 ttctacttct ttaatagatt taatttgttc tgttatcata ttaatagttt tttcatcagc
    26641 acagtgatct acaagttgat ttatagaatt cttataaata tctatagaaa ctttaattat
    26701 aaatatacat attactaaag atgctatagg gtctaatatt ggatatttaa gtctagctcc
    26761 aactattcct ataagtgttc ctatagatga gaaagaatct gatctatgat gccaggcatc
    26821 tgcttcaagg gctgtactgt ttattttttt agctgccttt aaagtatatc tgtacatcca
    26881 ttcctttgtg actatggata aaatagcaac ataaatagtt atttttgaag gaacagaaaa
    26941 atctttattt attataacct ttattccact atagcctatg aacaaagcag ttaaaaataa
    27001 catagtagct aataatttag aagttactgc ttcaagtttt tcatgaccat aggggtggtc
    27061 tttatctgca ggtttagaag aaattttaag acctatgatt actgcaatag tgcttaaaac
    27121 atcagagaga gaatgtatac cgtctgcaat agtagcagca ctatgtccta tgattccaaa
    27181 tagtactttt ataaaggaca aaattatatt tactataatg gttatattag aaactttatt
    27241 acctattttt aacctttctt cattttccat ctttccacct cattattaat tgaaaataaa
    27301 catttatatt attatatgct aaacatagca taaatgcaac aaaataaaga tagaaatgct
    27361 ttatcaattg atattaataa ttgaagatta tgtataatga gtatcaatat ttatattata
    27421 tgtttttaat acaataggat taac
//
