LOCUS       c00008_NZ_JAHL..       15484 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAHLNC010000008.1 Clostridium senegalense strain N2 O-25_ctg0008,
            whole genome shotgun sequence.
ACCESSION   c00008_NZ_JAHL..
VERSION     c00008_NZ_JAHL..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:41:57
            Original ID  :: NZ_JAHLNC010000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15484
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15484
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[561:5484]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      562..5484
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15484
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15484
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             562..1878
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Fer4_10 (E-value: 2.7e-11, bitscore: 37.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.3e-15, bitscore: 49.2,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.2e-52, bitscore:
                     169.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.8e-42, bitscore: 136.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLFSFKGGIHPPHGKTLSKDKAIEPLLPKKDLVFPMSQHIGAPC
                     EPIVKKGDRVLVGQKIGQATGFVSAPIHSSVSGTVKNVVPMLHPSGKKIMSIVIENDGL
                     YEECEFTPHEDYKSLSKDELLKIINEGGIVGLGGACFPTHVKLSPKQEIDTIIINGAEC
                     EPYLTCDYRLLLEKHAEIIEGLEIIKHMFPKANIYIGIEDNKSDAISILQSALEEYKGI
                     EVKSLKTKYPQGAEKQLIYALTKRAVPTGKLPADVGCIVQNLATIYAIRDVVIKGRPLT
                     DRIVTITGEAVKEPKNLQVKFGTSLTELVDACGGFKEDPVKVLSGGPMMGMSLISLEVP
                     SIKGTSGVLALLKDQADLSEESNCIRCGRCVTACPMWLVPSKLNSLVLRGEFEEFEKNS
                     GLSCIECGACSYICPAKRHLTQSCREGKRVIMNNRKKSK"
     CDS             1894..2835
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.9e-122,
                     bitscore: 399.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKLFTVSSSPHIKSKDSVNTIMRDVVIALMPALIAGVIYLGIG
                     ALVVTIACVVSCVVFEYLFQKITKRPITIKDLSAVVTGILLAYNLPPTAPIWICVVGSA
                     VSIIVVKCFFGGIGQNIVNPALLGRAFLLSAYPGHMTEWTLNGVSTATPLAIAKYGGGS
                     MPSIADAFLGNVGGCIGEISALALLIGFAYLLYRKVITFHIPVAYIGTTLILTLILGFI
                     GRDSFTVNQAIIEMFSGGLMIGAIFMATDYTTSPMTKKGQVIFGVCCGILTTVIRIFGG
                     YAEGVSYSILIMNLFVPIIDKYVKPRAFGEVK"
     CDS             2836..3396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="FMN_bind (E-value: 4.1e-23, bitscore:
                     75.3, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKENFKLGGILLIITAIAGLILSVAHSVTMGPILAKEKEEKVAAM
                     KVILPEAEDFTTVKDVEITEEILGVEAGTKDGKNVGYCINVSSKGYGGPINMMIGISED
                     GKIEGVQILSLSETPGLGSKAKEPEFIDQFKDKEATELSVDKESGSDDKILAISGATIT
                     SKAVTAGVNNAVKLFNENLKGAQ"
     CDS             3399..4016
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.2e-70, bitscore:
                     228.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLTERLKAGIIVENPVFIQVLAMCPTLATTSNVKNAIGMGLAA
                     TAVLIGSNAVIALLRKCIPDKIRIPAFIVIIASFVTLIQFLVQGYLPDLYKELGLFIPL
                     IVVNCIILGRAEAYASKNTVIDSIFDAIGMGLGFTLALTVLASVREILGAGTFYGLQVL
                     PKAYEPAGIMLLAPGAFITLGVLLAILNQYKISSAKKSKLSK"
     CDS             4036..4611
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-61, bitscore:
                     201.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGLFAIFISALLVNNVILSKFLGICSFLGVSKKTETAKGMGLAVV
                     FVMILASIITYIVNKCILIPLDIGYLSTLAFVLVIAALVQFVEIVVKKTNPSLYKALGI
                     FLPLITTNCAVLGIAVLNMDNNYNLIESIVNSAGAALGYMLAIVLLAGLRERMEENTDI
                     PEAFKGLPLALITAGIMAIAFFGFSGLI"
     CDS             4624..5484
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 26.3; E-value:
                     1.5e-08)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_6"
                     /sec_met_domain="Fer4_7 (E-value: 5.6e-09, bitscore: 30.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_9 (E-value: 9.4e-10, bitscore: 32.1,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.4e-09, bitscore: 28.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.8e-07, bitscore: 24.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3.8e-16, bitscore: 52.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.4e-06, bitscore: 19.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIGIKEILFPVLSLGGLGLLFGLLLGYANDKFKVEVDDRIPKVR
                     NCLPGANCGACGFAGCDAYAEAVVNDGAKPNLCNPGGATASAGISEILGVSVETSDPQV
                     AYVKCNGTCDKAKTKSIYYGVKDCNMAMNTPGTGNKSCDFGCLGLGSCVKACKFDALEI
                     VDGIAKVNKENCVACGACVTACPKGVIALVPKESKVRIQCNSNNKGKDVMDACAVGCIG
                     CGLCAKNCPKEAITMVNNLPVIDYSKCVNCGICATKCPKHCIENLRKPANTNKVEPKES
                     ETIKA"
     CDS             5692..6111
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MEQNGVVKRINGDIAEIAFIKKSGCGGNCGSCKSPCPSDTIIIPV
                     ENTLNANIGDTITVSVNNKAFSSMTFWAYVFPTIMTLIGLFGGVFTFKALNISNYELFG
                     AIIGLIFLVVSFLLSSKLNKKSKDGSYDFKMIKKN"
     CDS             6285..6953
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MNIASMIDHTILKADTTLDQVKKICDEAKEYKFKSVCVNSCYTKF
                     VAEQLKDSGVLVCTVVGFPLGAMDSKAKAFETARSIELGANEIDMVINVGALKDKNYDL
                     VLNDIKEVVETAKGKALVKVIIETCLLTDDEKVKACELSVEAGADFVKTSTGFSTGGAN
                     AKDLQLMRKVVGPNIGVKASGGVRTKADVLNAIEAGANRIGASASVAILNDDKSVKSDY
                     "
     CDS             7660..9162
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="LTFLIGLLKLSPVGVLVGLMISGMDVLIAAPLATCWAALMAYLTE
                     KIKFNDLIDCAVDNVKSMQLVFFILMFAYAMAAAFMATGVGAAIVNVALKLGLTARTVA
                     VTSFIVTCILSVATGTSWGTFAACAPIFLWLSHIVDGNVLLTVAATAGGSCFGDNIGLI
                     SDCTVVSSGIQKVEVIDRLKNQGVWSIICLVITAIAFYFLSTYLGLSNASSTNAASAID
                     AIPKEVWGVLQEQRPAAVDLLNQVKLGVPIYMVIPLILVIGAAIKGLSTLSCLFLGIIS
                     SLILGLFAGTTSVPEFLKLVEGGFSEAGQTVIVMMMWVGAFGGIMGKMKAFEPISKLVV
                     SISRNVRQLMFWNGVLSIAGNALLADEMAQIVTIGPIIKEIVDENVEASEEDMYQLRLR
                     NATFSSALGVFGSQIIPWHVYLGFYVAISNAVYPLYTFTPVDFIKYNIMAFVAIISLLL
                     LTFTGLDRFIPYFGIPSEPQVRLKKKSASTDDNYNDELEATS"
     CDS             9530..11017
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="LTFKKIIIGFLKLSPVFLLAGLMMMKMDALMAAPLSTLYAAIIAT
                     ITEKIKFNELVDCAVDNVKSMQLVFFILMFAYAMASAFMSTGVGASIVNLALELGLTAR
                     TVAVTGFLVTSILSIATGTSWGTFAACAPIFLWLSHIVDGNILITVAAIAGGSCFGDNI
                     GLISDTTVVSSGIQNVEVIDRIKHQGVWSLSCLVITAILFYIISLKLPTTVSSGSAAID
                     AIPKEVWGVLQEQKPEAVDLLNQVKSGVPYYMIIPLILVIAAAVKGIPTLACLSIGIIS
                     SLILGTFAGTTNLTDFLALVQGGFEEAGKWVIVMMMWVGAFGGIMARMKAFEPLSRLVV
                     LFSRNVRQLMFWNGVLSIAGNALLADEMAQIVTIGPIIKELVEENVEGDDEAMYKLRLR
                     NATFSDALGVFGSQLLPWHVYLTFYAGIASAVYPLRQFAATDFIKYNIMAFVAVISILL
                     LTLTGLDRFIPLFKLPREPEVKLKKKSLNNDNSISIN"
     CDS             11197..12096
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_11"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 2.3e-31,
                     bitscore: 101.8, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKISKLLPLTLSVAVIGSCAFSYFSYCRQYLPENNEKYEMVMQT
                     IKAEKDKNNKPLEKKEKKAEKMDTNVDNTCIDWWFVPNGNHEAPRLNDKLSFKFEDYDA
                     HCLGDTSKKVLYLTFDEGYENGYTDKILDTLKENDVKAIFFVTLPYIRDNQDIIKRMVD
                     EGHIVGNHSNHHPSMPEVATDESKFNKEFTDVEELFTEITGTEMPKFFRPPMGKYSQRS
                     LAMTKNLGYKTVFWSFAYHDWDINNQPEPEKAKKKILDGLHNGSIMLIHAVSKTNNEIL
                     GDVIKEAKQQGYTFELLE"
     CDS             complement(12146..12406)
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MELKKRMKFIDPETKEVVELEEVDRIELNGNTYLLLAPLDNSDDA
                     YIYKIVNMEGEKYELTEVEDEKEFEAVVAEYDRLFDEEMNE"
     CDS             complement(12602..13945)
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="LFLPKDVEFIIDTLYKKGYEAFVVGGCVRDDILGKKPNDYDITTN
                     AKPNKVKEIFQSLKLKIIETGIQHGTITLVLNNINYEITTYRIEGDYLDNRRPSKVFFT
                     ENLKEDLKRRDFTINAMAYNNYVGLMDFFHGREDLNKGIIRSIGNANDRFNEDGLRMLR
                     AIRFSTQLNFKIEDKTKDAILSRSSLIKNISVERITEELKKILISDIPSKGINELVNLK
                     LMEYIIPEIINLVGFNQQSKYHDKDIYYHTMEVLDNVENNISLRLAALLHDIGKPNTFT
                     LDEKGGHFYFHEAEGAKICRSILERLKFDNKIKKTVVILVKNHMRVIKGNNKYKIKKYI
                     NEVGQENLNLIFSLMIADRLASHKDYRGYDDILNMKSMCNKIITSNEPLKVKDLQITGD
                     DIIRCGIKPGKEIGNILNNLLEKVLKDPSLNERNILINEILIYIKNNK"
     CDS             complement(13997..14878)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_14"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 2.4e-29,
                     bitscore: 95.2, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRKYYNILIIAIAFVVTLFGIINYKNLDEKRLKTTKVFNNNLYK
                     YNKDIYKPKNSKEFIQAVKAKDEDRAVSYYICNEKDEKIVYLTFDDGPSDNTSKILDIL
                     DKYDAKATFFVVGHEDEPSINTYNDIIRRGHAIGNHTYSHDYKYIYNSVENFSQDFDKM
                     QCFIKEKCNYDMEIARFPGGSNNTVSNRYHNDIMIDLSKCLIDKNITYFDWNVDSGDAN
                     GTTMDVDYIIKSTLEGARKFDSPIILMHDAPTKKTTVYALSCIIETLKNEGYEFRALNC
                     DEYVIQFLRAKY"
ORIGIN
        1 tattttttta gaaatcatcc tactttttta ccaaataata tatatttttc tctatgattg
       61 ttaaatttac tacatatttt tttaaatatt aaaatatttt tttaatttta tattaaaata
      121 atttttaaaa ttttgatata aaattatagt tataattcaa attaaagact tttcgtattt
      181 ttcgacattt ttcatctact ttttataata ttaatatttt taccatatat ttcatagcaa
      241 ttttgttgaa atatacagac ttttaaagga ttttaatatt actttttttc tactttacta
      301 tgtattttcc ttttaaattt aatagattta ttttaattgt attaaattta aagctatttt
      361 ttataaaaat taatgtttaa tatttctttt aaaatattaa acattaattt ttataattta
      421 tataaatttg ttaaattttt aatattaggt taaatatttt acaaatcgca taatttgtct
      481 tataatttta attgtataca tacatttaat ttataaatgt taattttttt aactttcaga
      541 atacaaaaag gaggattatt tatgggactt tttagtttca aaggtggtat tcatccacca
      601 catggaaaaa ctctaagtaa agacaaagca attgaacctt tactaccaaa aaaagactta
      661 gtatttccaa tgagccaaca tatcggtgca ccttgtgaac caatagtaaa aaaaggtgat
      721 agggttctag ttggtcaaaa aattggacag gctacaggtt ttgtatctgc tccaattcat
      781 tcaagtgtat caggtacagt taaaaatgtt gtaccaatgc ttcaccctag cggtaaaaaa
      841 atcatgtcaa tcgtaattga aaatgatggt ctatatgagg aatgtgaatt tactccacat
      901 gaagattata aatcactttc aaaagatgaa ctgctaaaaa ttataaacga aggtgggatt
      961 gtgggacttg gcggagcatg tttcccaact catgtaaagc tttcaccaaa gcaagaaata
     1021 gacacaatta ttataaatgg ggctgaatgt gaaccttatt taacttgtga ctatagatta
     1081 ttgcttgaaa aacatgcaga aattatagaa ggcttagaga ttattaaaca tatgttccct
     1141 aaagctaata tttatattgg tatagaagat aacaaaagtg atgcaatatc aattcttcaa
     1201 tctgcacttg aagaatataa aggtattgaa gtaaaaagtt taaaaactaa atatccacaa
     1261 ggtgctgaaa agcaacttat ttacgccctt actaaaagag ctgttccaac tggaaaactt
     1321 ccagctgatg taggttgtat agtacaaaat ttagcaacaa tctacgctat acgtgatgtt
     1381 gttataaaag gaagaccttt aacagataga attgttacta ttactggtga agcagttaaa
     1441 gaacctaaaa atttacaagt taaatttggt acttcattaa ctgaacttgt agatgcttgt
     1501 ggtggattca aagaagatcc agttaaggtt ttatctggtg gaccaatgat gggaatgtca
     1561 cttatatcat tagaagttcc ttcaattaaa ggtacctctg gagtattagc acttttaaaa
     1621 gatcaagcag atctttctga agaatctaat tgtataagat gtggtagatg tgtaacagca
     1681 tgccctatgt ggcttgtacc atctaaatta aatagtttag tcttaagagg agagtttgaa
     1741 gagtttgaaa agaatagcgg actatcttgt atagaatgtg gtgcttgttc ttatatttgt
     1801 cctgctaaaa gacacttaac tcaatcttgt cgtgaaggaa aacgagtaat aatgaacaat
     1861 agaaagaaaa gtaaataatt gaggtgaaaa aatatgtctg aaaagttatt tacagtatca
     1921 tcatctcctc atataaagtc taaagactct gtaaacacta taatgagaga tgttgttatt
     1981 gctttaatgc ctgctctaat tgcaggagtt atatatttag gaattggagc acttgtagtt
     2041 acaattgctt gtgtagtttc ttgcgtagtt tttgaatatt tatttcaaaa aataacaaaa
     2101 cgccctatta ctataaaaga tttaagtgca gttgttacag gaatactttt agcttataat
     2161 cttccaccaa ctgcccctat ttggatttgt gttgtaggaa gtgctgtttc tatcatagtt
     2221 gttaaatgct tctttggagg aattggacaa aatatagtaa accctgcact attaggtaga
     2281 gctttcttat tatctgctta tcctggtcat atgacagaat ggacactaaa tggagtttct
     2341 acagcaacac ctcttgctat tgctaagtat ggtggtggct caatgccttc aattgcagat
     2401 gcatttttag gtaatgtagg cggttgtatt ggtgaaattt ctgcattagc gttacttata
     2461 ggttttgctt atctattata tagaaaagtt attacttttc atattcctgt agcttatata
     2521 ggaactacat taattcttac attaatatta ggatttatag gtagagatag ttttactgtt
     2581 aaccaagcaa ttattgaaat gttctcaggt ggattaatga ttggtgcaat atttatggct
     2641 acagattaca ctacatctcc tatgactaaa aaaggacaag taatctttgg tgtatgttgt
     2701 ggtattttaa ctacagttat tcgtatattt ggtggatatg ctgaaggtgt atcttattca
     2761 atattaatca tgaacttgtt tgtacctata atcgataaat atgttaagcc acgtgctttt
     2821 ggggaggtaa aataagtgaa agaaaatttt aaattaggtg gaatacttct tataattaca
     2881 gcaattgctg gacttatatt atctgttgcc cattcagtta ctatgggacc tattttagct
     2941 aaagaaaaag aagaaaaggt tgcagctatg aaggttatat tacctgaagc tgaagatttt
     3001 accactgtaa aagatgttga aataacagaa gaaattcttg gcgttgaagc tggaactaaa
     3061 gatggtaaaa atgttggcta ctgtataaac gtatctagca aaggatatgg cggacctatt
     3121 aacatgatga ttggtatatc tgaagatggt aaaatcgaag gtgtacaaat tttatcacta
     3181 agcgaaactc caggccttgg tagtaaagct aaagaacctg agtttataga tcaatttaaa
     3241 gataaagaag ctactgaact atctgtggat aaagaaagtg gttctgatga taaaatttta
     3301 gcaatctctg gtgctactat aacatctaaa gctgttacag ctggagttaa taatgctgtt
     3361 aaactattta atgaaaatct gaaaggagcg cagtaatcat gagtaaactt acagaaagat
     3421 taaaagcggg tataattgtt gaaaaccctg tttttataca agttttagct atgtgtccta
     3481 ccctggctac tacaagtaac gtaaaaaatg ccattggtat gggccttgca gcaactgcag
     3541 ttcttatagg atcaaatgca gttatagcac tacttagaaa atgtattcct gataaaatca
     3601 gaataccagc atttatagtt attattgcta gctttgttac tttgattcaa tttttagtac
     3661 aaggatattt acctgattta tataaagagt taggattatt cataccgctt atagttgtta
     3721 actgtataat tcttggaaga gctgaagctt atgcttctaa gaatacagtt attgattcta
     3781 tatttgatgc tattggtatg ggtcttggat ttactttagc attaactgta ttagcttctg
     3841 taagagaaat attaggagct ggaacttttt atggattaca agttctacca aaagcttatg
     3901 aaccagcagg aattatgctt cttgcacctg gtgctttcat aactttagga gtactactag
     3961 ccatattaaa tcaatacaag atttctagtg ctaaaaaatc taaactttca aaataatata
     4021 aagaggtgaa taaatttggg actttttgca atatttataa gtgcgttact tgttaataac
     4081 gtaatcttat caaagttctt aggaatatgt tctttcctag gagtttctaa aaaaactgaa
     4141 actgctaaag gtatggggct tgctgttgta ttcgttatga tacttgcttc aataattact
     4201 tatatagtta ataagtgtat attaatacct cttgatattg ggtatttatc tacactagca
     4261 ttcgtattag ttatagctgc attagttcaa tttgttgaaa tagttgtaaa gaaaactaac
     4321 cctagtcttt ataaagcatt aggtatattc ttaccactta taacaactaa ctgtgctgtt
     4381 ttaggtattg ctgttttaaa catggacaat aactataact taatagaatc tattgttaat
     4441 tctgccggtg cggcacttgg ttatatgctt gcaatagttt tacttgcagg tcttagagaa
     4501 agaatggaag aaaataccga tataccagaa gcgttcaaag gattgcctct tgcattaatt
     4561 acagcaggaa ttatggctat agcattcttt ggattcagtg gtcttatata aggaggcatt
     4621 ttaatggaca ttggaattaa agaaatatta tttcctgtat taagccttgg aggtctcggt
     4681 cttttatttg gtttattact tggatatgct aatgataaat ttaaagttga agtagatgat
     4741 agaataccta aagttcgtaa ctgtctacct ggtgctaact gtggtgcttg tggatttgct
     4801 ggttgtgatg cctatgcaga agcagttgtt aatgatggtg ctaagccaaa tctttgtaat
     4861 cctggcggtg ctacagcttc tgctggtata tctgagattt taggtgtatc tgttgaaact
     4921 tctgatccac aagttgctta tgttaaatgt aacggaactt gtgataaagc taaaacaaaa
     4981 tctatttact acggcgtaaa agattgtaat atggctatga acactcctgg tacaggtaat
     5041 aaatcttgtg attttggatg tttaggctta ggaagttgtg ttaaagcttg taaatttgat
     5101 gctttagaaa tagtagatgg aattgctaag gttaataaag aaaactgcgt ggcttgtggt
     5161 gcttgtgtta ctgcttgtcc taaaggtgta attgctcttg tacctaaaga atctaaagta
     5221 cgtatacaat gtaattctaa taacaaagga aaagatgtta tggatgcttg tgctgtagga
     5281 tgtattggtt gtggcttatg tgctaaaaac tgtcctaaag aagcaattac tatggtaaac
     5341 aacttacctg taattgatta ttctaagtgt gttaactgtg gaatatgtgc tactaaatgt
     5401 ccaaaacatt gtatagaaaa tttacgtaaa ccagcaaaca ctaacaaagt agaacctaaa
     5461 gaaagtgaaa ctattaaagc ttaaaatttt agatagtaaa acttataaaa ccattagaga
     5521 agaatatatc ttctctaatg gttttaattt aaacaatatt tttatgtata tttatagttt
     5581 tttatttttg taaataatca attttttaga aattaacttg gaaacctata atcaactgta
     5641 tttgtatttt acatatattt aatttaatat taaattaagg aggcgaaagt tatggaacaa
     5701 aacggtgtcg taaaaagaat caacggcgat attgctgaaa ttgcttttat aaaaaaatct
     5761 ggatgtggag gaaattgtgg cagttgtaaa tcaccttgcc cttctgatac tattataatc
     5821 cctgtagaaa acacattaaa tgctaatatt ggagatacaa taactgtttc agttaacaat
     5881 aaagcatttt ctagtatgac tttttgggct tatgtatttc caacaataat gactcttatt
     5941 ggtttatttg gaggagtttt tactttcaaa gcattaaata tatcaaacta tgaacttttt
     6001 ggtgctataa ttggtttgat atttttagta gtttcatttt tactttcatc taaattaaat
     6061 aaaaaatcta aagatggcag ttatgatttt aagatgatta agaaaaatta atatctttaa
     6121 aaacataact aattgacata tttttcttta cagtatataa tatattttta aatatactgt
     6181 ataaataaag tatatttttt gttttttaat ataatataaa tatttatgta gttaatatgt
     6241 tatattaatt attattaaat atataatttt tggaggttac caatatgaat attgcatcaa
     6301 tgatcgatca cactatatta aaagctgata ctacattaga tcaagtaaaa aaaatatgtg
     6361 atgaagcaaa agaatataaa tttaaatctg tatgtgttaa ctcttgttac acaaaatttg
     6421 ttgcagaaca attaaaagat tctggagttc tagtttgtac tgttgttggt tttcctctag
     6481 gtgctatgga ttctaaagca aaggcctttg aaactgcaag atctatagaa cttggagcta
     6541 atgaaattga tatggttata aatgtaggag cattaaaaga taaaaactac gatttagttc
     6601 taaatgatat taaagaagtt gttgaaactg ctaaaggaaa agcacttgtt aaagttataa
     6661 tagaaacttg ccttttaact gatgatgaaa aagtaaaagc ttgtgagctt tctgtagaag
     6721 ctggtgctga ttttgttaaa acttcaactg gttttagtac aggtggtgct aatgctaaag
     6781 atttacaact tatgagaaaa gttgtaggtc caaatattgg agttaaagca tctggtggag
     6841 ttagaactaa agctgatgta ttaaacgcta tagaagctgg tgctaataga attggagcta
     6901 gtgcttccgt tgcaatttta aatgatgata aatctgtaaa atctgattat taatatctta
     6961 aatggtatgt tattttatta aaagataaca taccattttt atattttata aatagatttt
     7021 atattaaata tatgtaatta tatatacatt taacaatgtg taaaataatt gtatgtcatt
     7081 catttatttt acacattgtt aaaagtaatt taattttttt gtaaaaataa cttgttaatt
     7141 tactctttat tatttataat aaaaaaagat tttcctaaat aaccattatt tatgaatatt
     7201 atgttaataa aatgttaatt ttatattttt cttatcttca ttttgttaat ttttttacat
     7261 tttcatttaa ttaaacccta ttttttctta taaatattta attaaatggc ttatattgtt
     7321 agattcggta tatattttat aacttttaaa tttaaatata tataaaaaaa tatgatataa
     7381 tagacatata agatttaaaa tttaaataaa tttaaaaatc aattagaatt ttcttgaata
     7441 tacacgtaga ttttttaata tatgtatata aattattaat aaagtattag aattttctca
     7501 aaacattgaa ttgtttattt tttcattcta taatttactt aaacatacaa aattatttca
     7561 aaaaacttat aaatctactt ttttttaatt tttatttatt attttatttt tttagttacc
     7621 atcattataa agatggttaa cgtagagggg gaatttatat tgactttttt aattggactt
     7681 ttaaaacttt caccagttgg agttcttgta ggtttaatga tatctggaat ggatgtttta
     7741 atcgctgcac cacttgcaac ttgttgggca gcattgatgg catacttgac agagaaaatt
     7801 aaatttaatg atcttattga ttgtgctgta gataacgtaa aatcaatgca acttgttttc
     7861 tttatactta tgtttgcata tgctatggca gctgcattta tggctactgg cgtaggtgct
     7921 gctatagtta acgttgcatt aaaattagga ttaacagcta gaacagttgc tgttacaagt
     7981 tttatagtta cttgtatttt atctgttgct actggaacgt catggggtac ttttgccgct
     8041 tgtgcaccta tattcttatg gctttctcat atagttgatg gaaatgtttt attaacagtt
     8101 gctgccactg caggtggttc ttgctttggt gacaatattg gacttatatc tgattgtacc
     8161 gttgttagtt caggtattca aaaggtagaa gttatagaca gacttaaaaa ccaaggtgtt
     8221 tggtctatta tatgtctagt tataactgct atagcattct atttcttaag tacatatctt
     8281 ggactttcaa acgcatcttc tactaatgca gcttcagcta tagatgctat tcctaaagag
     8341 gtatggggtg tgttacaaga acaacgtcct gctgctgtag atttattaaa ccaagttaaa
     8401 ttaggtgttc ctatatatat ggtaattcct ttaattcttg ttataggtgc tgctataaaa
     8461 ggtttatcta cattatcttg tttattctta ggaattattt cttcactaat cttaggatta
     8521 tttgcaggaa ctacttctgt acctgaattt ttaaaattag ttgaaggtgg attctctgag
     8581 gcaggacaaa ctgtaattgt aatgatgatg tgggttggtg cttttggtgg tataatgggt
     8641 aaaatgaaag cctttgaacc tatttctaaa ttagttgttt ctatttcaag aaatgtacgt
     8701 cagcttatgt tctggaatgg tgttctttca atagctggta atgcacttct tgcagatgaa
     8761 atggcacaaa tagttactat tggacctatt attaaagaaa tagttgatga aaatgttgaa
     8821 gctagtgaag aagacatgta tcaattacgt ttaagaaatg ctactttttc aagtgcatta
     8881 ggagtttttg gttctcaaat aataccatgg catgtttatt taggattcta tgtagcaatt
     8941 tcaaatgctg tatatccact atatacattt acaccagttg actttataaa atataatatt
     9001 atggcattcg ttgcaataat ctcattatta cttcttacct ttactggcct tgatagattt
     9061 ataccttatt tcggtatacc aagcgagcct caggttagac ttaaaaagaa atctgcttct
     9121 acagatgaca attataacga tgagttagaa gcaacttcat aatatatgta tgtagagcta
     9181 gcattatata aatgctagct tttttattat tttaatatat aacttttctc tcttatttca
     9241 ttataaaatt acatataaaa attcactttc aacataattc tcctttatta attataggtt
     9301 tataacttta ttaacaaatt gttagaattt tctaaagata ttgaattttt ttttgtatgg
     9361 ccttataatc tacttataac caaaccttgt tttagcatta aatgactagt ttataaatat
     9421 tcatatatat ttaacataaa atatatgaaa tattttaact ctacttttaa ttctaaaaca
     9481 aacatacgct ttaaccaaac tttgacgtta taaaaagggg gagtttatat tgacttttaa
     9541 aaaaattata attggttttt taaaattatc tccagtattt cttttagctg gtttgatgat
     9601 gatgaaaatg gatgctttaa tggcagcacc actttcaact ctttatgcag ctataattgc
     9661 cacaataaca gaaaaaatta aatttaatga acttgttgat tgtgctgtag ataatgtaaa
     9721 atcaatgcaa cttgttttct ttattctaat gtttgcctac gctatggcat ctgcatttat
     9781 gtctactggt gttggtgcat caatagttaa cttagcatta gaacttggtc ttactgctag
     9841 aactgttgct gttacaggat ttttagttac ttcaatactt tcaattgcta caggtacttc
     9901 ttggggaact tttgcagcct gtgctcctat atttttatgg ctttctcaca ttgttgatgg
     9961 caacatactt ataacagtgg cagctatagc tggtggttct tgttttggtg ataatattgg
    10021 tcttatatct gatactactg ttgttagttc cggtatacaa aatgttgaag ttattgatag
    10081 aattaagcat caaggggttt ggtctttaag ctgtttagtt ataacagcaa tcttatttta
    10141 tataatttca ttaaaattac ctacaactgt atcttcagga agtgctgcta tagatgcaat
    10201 tcctaaggaa gtttggggtg tgttacaaga acaaaaacca gaagctgtag atttactaaa
    10261 ccaagttaaa tctggagttc cgtattatat gataatacca ctaattcttg ttatagctgc
    10321 agctgttaag ggtattccaa cacttgcttg tttatctata ggtattatat cctctttaat
    10381 attaggaaca tttgctggaa ctacaaattt aacagacttc ttagctttag ttcaaggtgg
    10441 atttgaggaa gctggtaaat gggttattgt aatgatgatg tgggttggtg cttttggtgg
    10501 tataatggcg agaatgaaag cctttgaacc tctatcaagg cttgtagttt tattttcaag
    10561 aaatgtacgt caacttatgt tctggaatgg tgttctttca atagctggta atgcacttct
    10621 tgcagatgaa atggcacaaa tagttactat tggacctatt attaaagaat tagttgaaga
    10681 aaatgttgaa ggtgatgatg aagctatgta caagcttcgt ttaagaaatg caactttttc
    10741 tgatgcatta ggagtttttg gatctcaact actgccatgg catgtatatt taacttttta
    10801 tgccggcata gcatctgctg tatatcctct tcgtcaattt gcagcaactg attttataaa
    10861 atataatatt atggcctttg ttgcagtaat ctctatactt ttacttactc ttactggcct
    10921 tgatagattt ataccattat ttaaattacc acgtgaacct gaagttaaat taaaaaaaaa
    10981 atcattgaat aatgataatt caatttcaat aaattaaaat tttaatataa tatttttaaa
    11041 aaggtacttg aaattaaaag ttcaagtacc tttttatata aaaaataaac tatactctac
    11101 tttctacttg taaaaaacta atattttctc attgtaataa aattctttaa atctgtgtaa
    11161 actaatatta tattgtgtag aaaggagagc acttaaatga aaaaaataag taaattactg
    11221 ccacttaccc tttcagttgc agttattggt tcttgtgctt tttcatattt ttcatactgc
    11281 agacaatact tacctgagaa taatgaaaaa tatgaaatgg taatgcaaac aataaaagca
    11341 gaaaaggata aaaataataa accacttgag aaaaaagaaa aaaaagctga aaagatggat
    11401 actaatgtag ataacacctg tattgactgg tggtttgttc ccaatggaaa tcatgaagct
    11461 ccacgtctga atgataaatt atctttcaaa ttcgaagatt atgatgcaca ctgtcttgga
    11521 gatacttcta aaaaagtttt atatttaacc tttgatgaag gttatgaaaa tggttatact
    11581 gataaaattc ttgatacttt aaaagaaaat gatgtaaaag caatcttttt tgttacctta
    11641 ccttatatca gagataatca agatatcata aaaagaatgg tagatgaagg tcatattgtt
    11701 ggaaaccact ctaaccatca cccttctatg cctgaagtag ccactgatga aagtaaattc
    11761 aataaagagt ttactgatgt agaagagtta tttactgaaa ttacaggaac tgaaatgcct
    11821 aaatttttta gaccaccaat gggtaaatat tcacaacgta gtttagctat gaccaaaaat
    11881 ttaggttata aaactgtatt ttggagtttt gcttatcatg attgggatat taataatcaa
    11941 cctgaacctg aaaaagcaaa gaaaaaaatt ttagatggtt tacataatgg ttctataatg
    12001 cttatacatg ctgtctctaa aacaaataat gaaattttag gagatgttat aaaagaagca
    12061 aaacaacaag gttatacttt tgaactttta gaatagaaaa aagatgccta tgaaaatgaa
    12121 taaacatttt taggcatctt ttttattatt cgttcatttc ttcatcaaat aatctatcat
    12181 attcagctac tacagcttca aattcttttt catcttcaac ttcagtaagc tcgtatttct
    12241 cgccttccat atttacaatt ttatatatgt aagcatcatc tgagttgtct agtggcgcta
    12301 ataataaata tgtattgcca tttaattcta ttctatctac ctcttctaat tccacaactt
    12361 cttttgtctc tgggtctatg aatttcattc tcttttttaa ttccattttt atttctcctt
    12421 tatgtataaa taatttgaat ataagacaat ttcaataaaa taatagatta aatcatttat
    12481 aaattctata gctttctatt actttttcat acctaacttc ctttttaaat catagtaaca
    12541 attatatact attagtattt atttaacaac gaatttatta caattatgtt aaatcattta
    12601 tctacttatt attttttata taaattaata tttcattaat taatatgttt ctttcattta
    12661 atgaagggtc ctttaaaacc ttttctaaaa gattatttaa aatatttcct atttcttttc
    12721 ctggctttat accacatctt ataatatcgt ctcctgttat ctgtaaatcc ttaactttaa
    12781 gaggttcatt tgatgttata attttattac acatactttt catatttaag atgtcatcat
    12841 atcctctata atctttatgt gatgctaacc tatctgctat cattagtgaa aaaattaaat
    12901 tcagattttc ttgtccaact tcatttatat atttcttaat cttatattta ttattccctt
    12961 ttataactct catgtgattt ttcactaaaa ttactactgt tttcttaatt ttattatcaa
    13021 attttaatct ttctaatata cttctacaaa tttttgctcc ttcagcctca tgaaaataga
    13081 aatgtccacc tttttcatct aaagtaaatg tattaggctt acctatatcg tgaagtaatg
    13141 ctgctaatct caaagaaata ttattttcca cattatctaa cacttccata gtgtgataat
    13201 aaatatcttt atcatgatat ttactttgtt gattaaatcc tacaagattt attatctctg
    13261 ggataatata ttccattagt tttaagttaa ctaattcatt tatcccttta gatggtatat
    13321 cacttattaa aattttcttt aattcttctg taattctttc tacacttata ttttttatta
    13381 atgagcttct actcaatata gcatccttag ttttatcttc tattttaaaa tttagctgtg
    13441 tactaaatct aattgctctt agcattctaa gtccatcttc attaaaacga tcatttgcat
    13501 taccaataga ccttattata cctttattca aatcttctct accatgaaaa aaatccatta
    13561 atcccacata attattataa gccattgcat ttatagtgaa atctcttctt tttaagtctt
    13621 ctttcaaatt ttctgtaaaa aaaactttac taggtcttct attatctaaa tagtcccctt
    13681 caattctata agttgtaatt tcataattaa tattatttaa aactaaggta attgttccat
    13741 gttgaatacc agtttctata atttttaatt ttaagctctg aaaaatttct ttcactttat
    13801 taggtttagc attagtagtt atatcataat cattaggctt tttccctaaa atatcatctc
    13861 taacacaacc acctacaaca aaagcctcat atcctttttt gtataaagtg tctattataa
    13921 attccacatc tttaggtaaa aacaaaaaaa tcccccctat taatcaataa atatatattt
    13981 tattactgat tatttactag tattttgctc ttaaaaattg tattacatat tcatcacaat
    14041 ttaaagctct aaactcatac ccttcatttt taagggtttc tattatacag gacaatgcat
    14101 atactgttgt tttttttgta ggtgcatcat gcattaatat tattggtgaa tcaaattttc
    14161 ttgctccctc taaagtactt ttaattatgt aatctacatc cattgtagtt ccattagcat
    14221 caccagaatc aacattccaa tcaaaatatg ttatattttt atctattaag catttactaa
    14281 gatctatcat tatatcatta tgatatctat tactaaccgt attattgctt ccgcctggaa
    14341 acctagctat ttccatatca taattacatt tttctttaat aaaacattgc attttatcaa
    14401 aatcttgaga aaaattttca acagagttat aaatatattt ataatcatgg ctataagtat
    14461 gattacctat agcatgacct cttcttatta tatcattata tgtgtttata gagggttcat
    14521 cttcgtgacc aacaacaaaa aatgtagctt tagcatcata tttgtctaat atatctaata
    14581 ttttagatgt attatcactt gggccatcat caaaagttaa atatacaatt ttttcatctt
    14641 tttcattgca tatgtaatat gaaacagctc tgtcctcatc ttttgctttt acagcttgta
    14701 taaattcttt gctattttta ggtttatata tatctttatt atatttatat aaattattat
    14761 taaaaacttt agtggttttt aaccttttct catctaaatt tttataattt attattccaa
    14821 ataaggttac tacaaatgct atggcaataa ttaaaatatt ataatatttt cttctcatat
    14881 aatcccttct tttcaaactt tattttttct attaaatatt cttttttagt ttacgtagtt
    14941 tatattaatt tattcttttc atatatgctt aataatataa aaagctatct aagaataaat
    15001 ttacttgtat tcttaaataa ctttctatat attatactaa atgaaaataa taatccctta
    15061 tctttaaata tctgttttta tttgttccaa aatcataata tggaactcta gagcaggatc
    15121 tataatgaat acattgtaat ttttcatcaa aataaaactc tatatcatca tgatatctta
    15181 ataatggtgt tgttgatact gcataaatgt agtcatattc aacccttaat accaatatcc
    15241 ctcctataca gtttaatacc tttactattt tttcttttga ctcttctaag tcccctttaa
    15301 aaggcaaagt ttcaaccctt ttattatggt aaatcgtttc tgttgacact gcacttggcc
    15361 tattaggtat ctcttgtaat cttcccttaa ctacacctaa gtttttaggt tttactatat
    15421 ttctacttat tattgttgat actgatgcta tacctaatcc taataaaatt aaatttcttt
    15481 tttt
//
