LOCUS       NZ_HE610978.1          23637 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HE610978.1 Oceanobacillus massiliensis str. N'diop strain Ndiop,
            whole genome shotgun sequence.
ACCESSION   NZ_HE610978
VERSION     NZ_HE610978.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:02:39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 698
            Orig. end    :: 24335
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23637
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[10698:14335]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..23637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..23637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(389..1627)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 171.3; E-value: 9.5e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-51, bitscore: 171.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTKKNKGMIIASIGSIPLIMTLGNSMLIPILPEMKSALKLSQMQV
                     SLTITVFSIAAAIFIPLIGYLSDRFSRKLIIIPSLILFGLGGLIAGLGAAVFPHAYIWI
                     LVGRTIQGIGAAGTSPIAMALTGDLFKGGEQSRVLGIYEASNGLGKVLSPILGSILALI
                     VWYFAFFTFPVLSLISALLVWIFIKEKSNRQAPPPFGKYVRGLLSVFKHEGRWLFTTYL
                     AGGTCLFTLFGILFYLSDNLETEYKIDGVLKGLILAIPLLVMVTTSYLTGSKIGKNLER
                     MKRLLLLGFLLKTLSYASLVFLDKLIPFLAVLALSSVGAGLILPCVNSIITGAVGKERR
                     GFVTSLYGSVRFLGVALGPPIFSRLMDWSKTGMFLSIASFTLIVGLLVLLLLHVKGKDG
                     KEQKNTPTRYNYM"
     protocluster    1501..22787
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[12198:13485]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      11501..12787
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             complement(1661..2161)
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MGALNNKPADEPLHSGEVYNLWSYLYSTKGTLVVMQVLINHTGDH
                     DLKVLLEDVLENSFTQEEQQVEALLKDSGIRLPPAPPDRPNVEVQDIPAGARFNDSEIA
                     VLVQKELMAGRMLCSYITGIAIKEDVRSMFSEFNTQKEEYELKLLKVTKEKGWLVSPPI
                     NIK"
     CDS             2357..3310
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MLKKISMFTMFFACVILAGCSLNNSSANSEDEGVIRIGYQKNGPL
                     IILKSLGTLEERLDSLGYTVEWNEFQAGPALVEALNAGSIDFGRTGNSPTIFAQAADTP
                     FVTVAAGRSKYEGSGILVPEDSEIKTAKDLKGKKISFAKGSSSHYLLVKALENAGLSYT
                     DIELVYLSPGDARIAFEQGQTDAMVVWDPYTASTEINMNATLLMNGEGLTTDRDFFIAN
                     EKFAEEHADLIKILEEEIVKSSDWANTNHDALVEMLAPILNIDDASIELAVERRIYGVE
                     KINEEIIQEQQEIADAFFRLDIIPKEINVRDVMDKQ"
     CDS             3331..4095
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 87.5; E-value: 3.1e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 3.9e-26, bitscore:
                     87.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTVLKMSMKKFIPWFFPLLLLVGWQVLSWAGAIPERILPAPTKV
                     LQAGLELSANGELVNHVSISLGRALAGFLIGGIIGFIFGLLNGVFRIADLFFDTSIQML
                     RNIPHLALIPLVILWFGIGETSKIFLVALGVLFPIYINTYHGIKSVDKGLVEMGRAYGL
                     KGITLFFNVILPGAMSSILVGIRFSLGVMWLTLIVSETISAHSGIGYMAMNAREFMQMD
                     VIVLSILLYAFFGKLSDVIARYLEDRLLLWNT"
     CDS             4114..4890
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="LQEAIHQKYIEINELQKNYGERAVLKGLNLHINKGEFVAIVGKSG
                     CGKSTLLRLIAGLEEFNEGSIQLNGEPLKDLNKYARIMFQDGRLLPWKRIIDNVCIGLP
                     RDYRIKAMDALQQVGLADRMNDWPSKLSGGQKQRVALARALVHDPLLLLLDEPLGALDA
                     LTRIEMQELIESLWKQRAFTSILVTHDVEEAVAIADRVILIEDGAISLNQPIRLPRPRQ
                     RTNPAFSMYVEEILEKILSRNPKKISLVKSSKELEM"
     CDS             complement(4894..5169)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MFNLLEKAIVAMALLRIASGSLEILAAFLIMKFNEIEKALIINSI
                     LALIGPMILIISTTIGLYSLADKISFDKMLWIVLGVAFIIYGIKSS"
     CDS             complement(5466..5762)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="LIDANYPLDAKGMVNIREYSQEQLRNIIKASITSLSEAEPFEENW
                     INNEEQILTITREFETWDVYAGELLDGTYATYNAAADYLQQEGFRRLKDEDAE"
     CDS             complement(5759..5929)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MLTFEEKLAIIESFQELKRHDVSLGRVNFHYEDSVMEKKPSYIIF
                     TQTETVSFMLS"
     CDS             6392..7285
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MNFGNVLTAMVTPFNEALEIDFEATGRLVDYLIANGSDGLVVAGT
                     TGESPTLSHNEKLELFEFVVKVADGRIPIIAGTGSNNTRASIELTKEAEATGVDAIMLV
                     SPYYNKPSQEGMYQHFRSIAESTELPVMLYNIPGRSVVNLEPETIVRLSEIKNIVSVKE
                     ASGDLDRTTEIISRTTDDFSVYSGEDSLTLPSLAIGGTGIISVASHIIGNEMQEMMEQY
                     KKGKPDNAAAIHHQLLPVMQALFAAPSPAPVKEALNRLGVDVGGVRLPLIPLSDAERES
                     LYNVIAHLERKEASGY"
     CDS             7688..8245
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXSIVCRNYGVVTSAPEIHCAFRGLALSQGTTCV
                     YFFVPLHRGSQLRSVTGKRRCI"
     CDS             8818..9474
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="LAEKVLFTSESVSEGHPDKIADQISDAVLDAALEQDPFSRVACEV
                     FNTTNTIIVGGEITTTATLDIEKIARDTLIEVGYTNDQFGIDGHTCDVQVLVHTQSPDI
                     AMGVNSSSDTKEIGAGDQGIMFGFATNETDSLMPLPIEMAHTLVKKASSLRKSGSFKWA
                     RPDMKSQVTIDYTVPDAPRIDTILMSIQHDGDFNKKNLRNMLSKISYRKRQGNFV"
     CDS             9516..10004
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="VVGGPHGDAGLTGRKIIVDTYGGAARHGGGAFSGKDCTKVDRSAA
                     YAARYVAKNIVAAGFAGKCEIQLSYAIGVSEPISISLETFHTEKVTHEQLLLAIRKVFN
                     LTPSGIIDMLNLRKPRYKQVAAYGHFGRSDLDLPWERTDKVEELHQAIETAAFAGVGQ"
     CDS             10001..11500
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_14"
                     /sec_met_domain="OKR_DC_1_C (E-value: 3.1e-11, bitscore:
                     39.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.8e-115,
                     bitscore: 380.7, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNNVHDLVASKKTLGEQNEMPLFAALVRYAEQEVTPFDVPGHKM
                     GAQMNPLKEALGEMTLRMDVNSMEELDLLSHPQSVIKKAQKLAAAAFGADHAFFLVNGT
                     TIGILAMIIAVCKPGEAMLVPRNAHKSVMEGIILSGANPIFIQPEIDYHFGISHNVSVS
                     KVKKAIDMHPEAKVMLLTYPTYFGSMTDLSEICRLAHERNITVIVDAAHGAHLGFMPGD
                     LADPISAGADAATISMHKTGGSLTQSSLLLLQNDRIPPQKIQQALNMLQTTSANYLLMS
                     SLDVARRELVLYGSKQYDELKPIVEEAIKTIECASNFEVLKASYVKNQYNQAYDWTKLV
                     IRVNGIGLTGFEVYKLLKEKYNIQVELAEGYVIMAVITSSDSKESIDRLVFALKEIERR
                     FGKQMVVMSTNVTADLVNELVLNPRDAFYAEQESIAIEDAAGRISGDTLMIYPPGIPLV
                     IPGEIISKEVIQQYHYYCETLGNVLTETKEADHITVIKENV"
     CDS             11501..11932
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_15"
                     /sec_met_domain="AdoMet_dc (E-value: 2.5e-42, bitscore:
                     139.1, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLEITALGRHVLIEYYGCPSEIIEDNALIEKFMRGAADYSGATI
                     VESVFHHFNPYGVSGAVIIAESHLTIHTWPEYGFASVDVYTCGDSVNPWKAADYLSEKL
                     QAKKTESFEVPRGMVDKIRQFAEQEIEEVKVKQALEGVN"
     CDS             11933..12787
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_16"
                     /sec_met_domain="Spermine_synth (E-value: 1.9e-48,
                     bitscore: 159.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 8.6e-09,
                     bitscore: 30.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNWYTEQWSGETKFSIAYDKQLYSEKTPFQQIDFYKGNEFGTFFT
                     LDGLMMVNEKDEFIYHDMIVHPAFATNPGIKSVLIIGGGDGGTAREVLRYRIVEKVVMA
                     EIDEQVFRLCQEYLPITASGIEEDSRMELRFEDGLAYVRNTPDQSFDLILVDSTDPISV
                     GEGLFTTEFYKECYRVLNKHGILINQHESPYFAEYAANMKKAHQKIKAIFPITNVYQYH
                     MPTYPSGHWLFGFASKSYDPLQDLQAEAWNKFGLETKYYNTDLHRGAFALPNYVKEALV
                     RDE"
     CDS             12780..13637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_17"
                     /sec_met_domain="Arginase (E-value: 1.2e-75, bitscore:
                     250.2, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKSLNLSTFIGCESSYKEAEIVLFGVPFDGTTSFRPGTRFAMQE
                     IRPDSFGLETYSPYLDKDLEDAAIFDGGDLELPLGNTAKAMDQIHAYTREVLQDGKKFL
                     MVGGEHLVSLPTIQAAYEKYPDLHLIHIDAHTDLREDYLGEKLSHASVIRRCHEFLGDG
                     RIFQFGIRSGLKEEFEWAGTHTYLERFSLATLMEKIQELKDVPVYITIDLDVLDPGIFP
                     GTGTPEPGGITYRELLKAIEQMQQLNQIVAADVVELSPPYDPSGASTAIACKTIRELLL
                     TLTA"
     CDS             13983..15446
                     /locus_tag="ctg3_18"
                     /transl_table=11
                     /translation="MTKTIFEIETLINNRIKEIQNMVADDPYRLHYHLMPQIGLLNDPN
                     GFAYYKGQYHIFYQWNPFETKHGIKYWGHYVSDDLVHWKELPIALAPDQWYDINGCYSG
                     SAVVHEDKLYLFYTGNVMDEEGNREAYQCIAVSEDGINFQKKGPIIHVPEGYTPHFRDP
                     KVYYKAGKWYMVIGAQTSEGKGEAVLYTSPDLESWSFQGPLAGSGHNGLGDFGYMWECP
                     DLFELDGHEVLIICPQGLTPRGYEFNNIFHAGYLAGEVDYHNVSFQHGPFTELDRGFDF
                     YAPQTMMDSKGRRLLIGWMGNAEEGESIHPTTRYEWIHTLTLPRQLEWKNGKLLQYPVV
                     ELESLRENQIEYEDVPVHEGELSLPNIQGSVFELEVTIKSGNPDVFSIKIGQNNQLSYD
                     QSTNTFSLQRMDLADNHAFEKRYCVLEELRSIRLYKDTSSIEVFVNEGEEVFSARIFDY
                     PNEQDINFYANGSLTMDVKKWELKKLKCL"
     CDS             15681..16241
                     /locus_tag="ctg3_19"
                     /transl_table=11
                     /translation="MQTNLYFVRHAHSIYTPDEINRPLSESGIADVKRVAECLFGQRID
                     TVISSPYKRAIQTIEAVAESVDKEIIVMEDFRERQLSETSVDDFQFAVSKLWSNPAFSW
                     KGGESNDTAQDRGIKATFEVLERYMGKNVVIGMHGNLMVLIMNYFDDRFDYTFWRNLTM
                     LDVYKLTFEARKLLFVERLWKQD"
     CDS             complement(16361..17227)
                     /locus_tag="ctg3_20"
                     /transl_table=11
                     /translation="MIEVSGISFSGDNLFAPGSIESIIIRNMKESVTVYAYQSKDELMF
                     EIELRKNIIASARAMEQSDMQFANFANSRCNPMYWDLTDAGGFQLKPNVLPSEAILDIY
                     RNSYLYAFECAVANVIIYYHALLTSIGLQLFNDLFQDLYLYSWHFDPDFGIRSLHSNHF
                     LPGDVVYFNNPDFDPAASWWRGENAVVMGDGTFFGHGLGIMTADRMIESLNSMRKAGST
                     QSAYLANVVTSPSFRHLANLSLNMRGLQSRKIPYIVIHHNESSISCSQYLFYLNMAYNP
                     AAFRNPF"
     CDS             17602..17787
                     /locus_tag="ctg3_21"
                     /transl_table=11
                     /translation="MKRKQQLYPLMAGLAGFGLTFIVTLLIESTHPFLASLVLGFIIFE
                     ISFYYFHSEEKRINEL"
     CDS             17881..18408
                     /locus_tag="ctg3_22"
                     /transl_table=11
                     /translation="MNSTVPKRIHIIGSVGSGKTTLAKELSIMLEIPYYELDNVVWRRC
                     NSGDKRRSEEERDEHLFRIIQSPSWIMEGVHNEDWVSNSFHQADLIIFLDTRYSLRTYR
                     IIKRFFKQKLRLEKSNYRPTLAIFFKMFKWNRHFEEVGKVNFFSKYGMLHDKTAVITNN
                     NGITELFKANNR"
     CDS             18432..18644
                     /locus_tag="ctg3_23"
                     /transl_table=11
                     /translation="VNEKEAPEQKRERLRQEELKKNPIGNAGDAFNSADSGNLADLVGG
                     LGWKGTGLIIAAIIVGLLLYSLFFR"
     CDS             19115..20113
                     /locus_tag="ctg3_24"
                     /transl_table=11
                     /translation="MKKTILTGIKPTGQIHLGNYIGAIKPALELAVEEDYSPIYFVADY
                     HGLTKTIDSEDFRSFSYGIAAAWLALGLNPEKTIFYRQSDVPEIFELNWILSCLASKGL
                     MNRAHAYKAIADNNRKAQKDKDYGVNMGLYNYPILMAADILMFRTGIVPVGKDQIQHVE
                     IARDIAESFNRKYGETFVLPDYNIQEDTAVLPGLDGRKMSKSYHNTIPIFSEQAKLRKL
                     INKIKTDSLPPEVPKDPDKSTIFMLYKEFALPAEVESMRQQFLTGVGWGEAKGQLFHVM
                     NRFLEQPRERYKELMENPETIDKVLKEGADKAREMSVPFLKEIKRKIGFYS"
     CDS             20695..21351
                     /locus_tag="ctg3_25"
                     /transl_table=11
                     /translation="LEKQVVVIGLGRFGRSVCKQLHELGHEVLAIDKKEERVKLASNYS
                     YYAVVANASDESVLKNYGVRNFDHAIIAIGDSIESSILCTLILKDMGVSNVWVKARDLH
                     HQKILEKVGADRIIQPEKEMGVRIANQLDSGKLLDYIELSKDYSIVELIATKKLSGKSL
                     IQLDIRAKYGCTILAIKQDETVNVSPMPEDIISKGDVLVVMGQVNDLKRFEDKGF"
     CDS             21351..22715
                     /locus_tag="ctg3_26"
                     /transl_table=11
                     /translation="MKISLKRFKLTYLSTIRLIVLFYIVAVIFSVVLLGLPFLHHAGEE
                     LSLIDLMFTAVSAISVTGLAVVSTPETFNTAGKIALTFVMQFGGIGIMTLGTIVWVILG
                     KKIGLRGRQLIQIDHNRASLAGSVKLILKILKTILLIELIGTVILSAYFMNYFDSWQEC
                     LLQGYFGAVSATTNAGFDITGSSLELFADDYFVQFVNIILLTLGAIGFPVLIELQNYMR
                     GDHLDGNPRNSFSLFTKLTTLTFFALIAAGAILIVLLEWNGFMADKVWHERLFFSLFQS
                     VTTRNGGLATMDVGEFSSPTLIVLCFLMFIGASPSSVGGGIRTTTFAIMLLAIYNFAKG
                     RTGIKVFGRELEQEDVIGSFMVITTASMLCMIAIITLTYIEPFSLIEIAFEVSSAFGTT
                     GLSLGITPELSTAGKCIIIFLMFVGRIGIFSFLFLIRGKETKENYHYPKEKVIIG"
ORIGIN
        1 tggacagtaa tagcgattac cgttacttcg atttctattg atttctttga acagagttac
       61 attccaaata gaaatttaat attagacctt ttatttggat ctgtatttct cggaaccggg
      121 atagggattc tgattcggca gggtgtctca aatggcggtg tcggagtagt ggctttgatt
      181 atttcctata agagaaaaat ccttccgggg aagcctctat taattgtaaa tggcgctatt
      241 ttcctggtta cggccattgc aatcgacatt aaattaatat ttcttgcttt aatcagtcaa
      301 tatatttcca cgaaaattgt caatcaagta tgtgcgttat catttgtaaa agcatatacg
      361 ttcgggtgga gaaaaaagcc gtagcaggct acatataatt ataacgagtc ggagtgtttt
      421 tctgttcttt tccatctttt ccttttacat gaagcagcaa tagtaccaaa aggccgacaa
      481 ttaatgtaaa ggaggcaatc gataaaaaca taccagtttt tgaccagtcc attaagcggg
      541 aaaaaatggg cggtcccaaa gcaactccca gaaatctcac cgatccgtac agggacgtaa
      601 caaagcctct tctttccttg ccgacagcac cggttatgat gctgttaaca caaggaagta
      661 tcagtcctgc accaacactg cttagtgcaa ggacagccag aaaagggatg agtttgtcca
      721 agaagacaag tgatgcgtaa gatagcgtct taagcaagaa gccaagtagc aataatcgtt
      781 tcattctctc tagattcttg ccgattttac tgccggtaag gtaagaggtc gttaccatga
      841 caagcaaagg gattgccaga ataagtcctt tcagaacacc atcaatttta tactctgttt
      901 ccagattatc ggataagtag aacaagatgc cgaaaagtgt aaaaagacaa gttcctcctg
      961 caaggtatgt ggtaaatagc catctgccct catgtttaaa gacactcaat aggcccctga
     1021 catacttgcc gaatggtggt ggtgcctggc ggttgctctt ttcttttatg aaaatccaaa
     1081 caagtaaagc ggatatcaga ctgagtactg gaaaggtgaa aaaagcaaaa taccatacaa
     1141 ttaaagccaa aatagacccg agtattgggg ataggacctt acccaatccg tttgatgctt
     1201 cataaatgcc cagcacccga ctttgttcgc cacctttaaa taaatctcca gtcaatgcca
     1261 tcgcaatcgg ggaagtccct gctgcaccga tcccttgtat ggtccttcca actagtatcc
     1321 aaatataggc atgaggaaaa acagctgccc ccagaccggc aatcaatcct cctaaaccaa
     1381 acagaatcag ggaaggaata atgattagtt tacgcgaaaa acggtctgag agataaccga
     1441 ttaaaggtat aaaaatggca gcagctatcg aaaagacggt aatggttaag ctcacttgca
     1501 tttgagaaag cttcaatgca gatttcattt caggtagtat tggaataagc atggaatttc
     1561 ccagtgtcat aatcagtggg atagaaccaa tggaggcaat gatcatgcct ttatttttct
     1621 ttgtcacttt ctctccactc ctcaaggtcc attgaataat ttacttaatg ttaatcggcg
     1681 gggaaaccag ccagcctttt tccttcgtaa cttttaataa ctttaattca tactcttctt
     1741 tctgggtgtt gaattcacta aacatggaac gtacatcctc tttaatagca attcctgtta
     1801 tatagctgca taacattctg ccagccatca attctttttg aacaagtaca gctatttcag
     1861 aatcattgaa ccttgcaccg gctggtatgt cctggacttc tacgtttgga cgatctggcg
     1921 gtgctggtgg taaacgaatc ccggagtctt ttaacaatgc ttccacctgc tgttcttcct
     1981 gtgtaaaact attctcaagc acatcctcca aaagtacctt cagatcatga tcaccagtgt
     2041 ggttaatcaa cacttgcatg actactagtg ttccttttgt gctataaaga tatgaccata
     2101 gattatatac ttctcctgaa tgcaatggtt catctgctgg cttattattc aatgctccca
     2161 tatggatacc tccaagtgat tttatctgta taagttttcc taaaaagaaa taaattatcc
     2221 ggtattttta tggtaatcaa ttgaatgaga aagaaggtta gttttaaagt ttcaaacggg
     2281 acaggaacct actttttatt tatacataat ctaaacacag atataaattt catttttgca
     2341 aggatggttt ttggatatgc ttaaaaaaat ttctatgttt acaatgtttt ttgcatgcgt
     2401 tattttagct ggctgcagtt tgaataattc atctgccaac agtgaggatg agggtgttat
     2461 tcggataggt tatcagaaaa atggccctct gatcatttta aagtcattag gaacacttga
     2521 agagagactt gattcacttg gctatacggt agaatggaat gaattccagg caggtccagc
     2581 attggtagaa gctttaaatg caggaagtat agattttgga agaactggga attcaccgac
     2641 aatctttgca caggctgctg atacaccttt tgttacggta gccgccggga gatcaaaata
     2701 tgaggggagc ggtatcttgg taccagagga ttcagaaatc aaaacagcta aagatctgaa
     2761 ggggaaaaag attagttttg ctaaaggatc gagttcccat tatctgcttg taaaggccct
     2821 ggaaaacgcc ggcttaagct atacggatat cgaactagtc tatttgtcgc cgggtgatgc
     2881 gaggattgct tttgaacaag gacagacaga tgcaatggtt gtatgggatc cgtatactgc
     2941 ttcgacggaa atcaatatga atgcaacact tctaatgaat ggtgaagggc ttactaccga
     3001 tagggatttc ttcattgcca atgaaaagtt tgctgaagaa catgcggatt taatcaaaat
     3061 attagaagaa gaaattgtaa aatcatcgga ctgggcaaat acgaatcacg atgcgttagt
     3121 cgaaatgctt gcacccattt taaatatcga tgatgcatca attgaattgg ctgtagagcg
     3181 aaggatttat ggagtagaga aaattaatga agaaatcata caggaacaac aggaaattgc
     3241 tgatgcgttt tttcgactgg atattatccc taaagagata aacgttcggg atgttatgga
     3301 taaacaatag agaaacggag ggtagggcaa atgaaaactg tattaaaaat gtcgatgaag
     3361 aagttcattc cctggttttt ccctctcttg ctgctggtcg gctggcaagt gctgtcgtgg
     3421 gctggagcta ttcccgaaag gatactgcca gcaccaacga aggtattgca ggctggtctg
     3481 gaactttcag ccaacgggga attggtgaac catgtatcca tcagccttgg gagagcgctg
     3541 gcgggattcc ttatcggagg aataatcgga tttatttttg gattacttaa tggggtgttc
     3601 cggattgctg atctgttttt tgacacttcc atacaaatgc tgcggaatat tcctcatctg
     3661 gcccttattc cacttgtaat attatggttt ggaatagggg aaacatcgaa aatatttcta
     3721 gtggcacttg gtgttctttt tccaatctat ataaacacgt atcatggcat caagtcggtt
     3781 gataaaggct tagtggagat gggaagggca tatggactga aaggaattac actgttcttc
     3841 aatgtgatac ttcctggagc gatgtcttct attttagtgg gaatccgttt ttcgcttggg
     3901 gtcatgtggt taacgctgat tgtgtctgag acaatatctg ctcattccgg aattggttac
     3961 atggcaatga acgcaagaga attcatgcag atggatgtta ttgttttgag tatattgctc
     4021 tatgcttttt ttggaaagct atcggatgtc attgcaagat atctcgagga tcgattactt
     4081 ctttggaata cgtaatgaaa tgggggaact aaattgcaag aagctataca tcagaaatat
     4141 attgagatta atgaactgca aaagaattac ggagaacgag ctgttcttaa aggattgaat
     4201 cttcatataa acaaaggaga gttcgttgca atagtaggta agagcggttg cggaaagagt
     4261 accttgctcc gcttgattgc tggattggaa gagtttaatg agggttcgat acagttaaac
     4321 ggcgagccgc ttaaagactt aaataaatac gctcgcatca tgtttcagga tggccgtctg
     4381 cttccgtgga agcgaattat cgataatgtc tgcattggac tgccgagaga ctacagaata
     4441 aaagcgatgg acgcactgca gcaggtgggg cttgcggatc ggatgaatga ttggccatcc
     4501 aaactatccg ggggacaaaa gcaacgagtg gccttggcaa gggcgttggt tcatgatcct
     4561 ttgctgcttt tgctggatga accgctcggg gcccttgatg cacttacaag aattgaaatg
     4621 caggaactga ttgagtccct gtggaaacaa agagcgttta cctctatcct ggtgacccat
     4681 gatgtggaag aggctgttgc cattgcagat cgggtaatct tgattgaaga tggggctatc
     4741 agcctaaatc agccgatacg acttccaaga ccaagacagc ggacgaatcc agctttttcc
     4801 atgtatgtag aagagatact cgagaaaata ttaagtcgta atccgaaaaa aatctcattg
     4861 gtaaaaagct caaaggagtt ggagatgtaa agatcagctg ctctttatcc cgtaaatgat
     4921 gaatgccact cctaaaacaa tccagagcat tttatcaaat gaaattttat ctgctaagct
     4981 gtaaaggccg atggtggtgg atataatcaa gatcatcggt ccaattaatg caagtatact
     5041 gttaataatt aatgcttttt caatttcatt aaacttcatg attaaaaaag cagcgagtat
     5101 ttccaaactt cccgatgcta ttcttagaag tgccatggca acgattgcct tttccaataa
     5161 attaaacatt gttctcctcc tgcatatttc tttctcaaat tatatgcaaa tcctatccat
     5221 aaaaggacaa ctattaagac atcatgaata caaaatcgta tatgtctgta tatattgggt
     5281 gcaggttgat aggattattt gaagtctatt ttccaattat attcatagtc aatgcggagg
     5341 gaatcgggat gggaaataaa gattgtttta aaaaatggag caaaaaaatg tgccatggca
     5401 aatggcacat ttgatcgttt aaatatagca tacgcttcta aaacattatt gatagaacta
     5461 aaggattatt cagcgtcctc gtctttaagg cgtcggaagc cttcctgctg taaataatct
     5521 gccgcagcat tgtaagtggc atatgttcca tccaataact caccggcata aacgtcccat
     5581 gtttcaaatt cacgcgtgat ggtaagtatt tgttcttcat tgttaatcca gttttcttca
     5641 aatggctcag cttcagatag ggaagtgata gatgctttta taatatttcg gagctgttcc
     5701 tgactatatt cgcggatgtt taccatccct ttagcatcaa gtggataatt tgcatcgatc
     5761 aactcagcat aaacgaaacc gtttccgttt gggtgaagat gatatacgac ggttttttct
     5821 ccataacact gtcttcataa tgaaaattga cacgtcccaa tgacacatca tgacgcttaa
     5881 gttcctgaaa tgattcaata attgctagtt tctcttcaaa tgtaagcatg tgacctccga
     5941 gttgatataa tttattaatg caaaactatt ataccactac gatgatgaat aatacgatgg
     6001 gattgtagac attcatcacg tgcgattttg aaatgattgt gtttataggt ttttattgtt
     6061 ataatacacc taacaattga atactttctt attttagata tcttaaggta agggtagagg
     6121 tgcaaaaacc ataagtactc gtgttgaaga gaatgagctc tgacgataca ggaggaaagg
     6181 ggaatttgcc gaagctgatg gtgactcatt atccggaagc tggtgctgtc attcaataga
     6241 tgcaggactg tcatataggt aactatatgg agggctatca agcgtagaac tatagtagac
     6301 gttctaagca gcagcgggtc ctctcgctgg tgctttttat tttggtcctc cacacctatc
     6361 gaaaaaaatc caataaaagg tgtgtgaagt tatgaatttt ggtaatgtat taacggcaat
     6421 ggtaactcct ttcaatgaag ctttggaaat tgactttgag gcaacaggca ggctggtcga
     6481 ttatttaatt gccaatggtt cagatggtct agtggtagca gggacaactg gagaatcgcc
     6541 gacattgagc cataatgaaa aattagagct atttgaattt gttgtcaagg tggcagatgg
     6601 aagaataccg attattgctg gtacgggatc gaacaataca agggcatcca ttgaattgac
     6661 aaaagaagcg gaagcaaccg gtgtagatgc cattatgcta gtttctccat attataataa
     6721 accatcacag gagggcatgt atcagcactt tcgctccatc gctgaaagta cggagttacc
     6781 tgtaatgctt tataatattc ccggccgtag tgtagttaat ttggaaccgg aaacgattgt
     6841 tcgcctgtcg gaaataaaga acattgtgtc agttaaagaa gccagtggtg atcttgatcg
     6901 cacaacggaa atcatcagcc gtacaacgga tgactttagc gtatatagcg gagaggatag
     6961 tctgacatta ccctcacttg caataggtgg cacagggatc atatctgtag cttcccatat
     7021 tatcggcaat gaaatgcagg agatgatgga gcaatataaa aagggcaaac cagataatgc
     7081 cgcagcaatc caccatcagc tcttgccagt gatgcaagca ttgtttgctg ctccgagtcc
     7141 agcccctgtt aaagaagcgt taaatcgact tggagtggat gttggcggag tgcggctgcc
     7201 tcttataccg ctaagtgatg cggagcggga atcactatac aacgtaatag cacatcttga
     7261 aagaaaagaa gcatccggat attgaccaat taagggatag gcttatttgc ctgtcccttt
     7321 ttcaagtgaa tcattccatt gacttataat gacatactcc ttaagcgaat gtttactcat
     7381 atctattaga aaacagcttt taaaaaaagg ctcttttcgt aaatattgtt gttatttcta
     7441 acttcgtatt tgatggaaac tgcgacataa caatatatga ttggtgattt atccccactc
     7501 cggaaataca ctacgctttt cgcgggctcg tgtaagccag agcactgctt gcgattgctt
     7561 ccttgttccc ttgcaccgag gaagcctgtt tcgaagcgtt actggaagac gcaggtgcat
     7621 ctagcggggg cttagcgttt tcagtttttc tgaagacaaa aaagctaaag tgaatttcct
     7681 catttctatg ctgctctnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng tcaattgttt gtagaaatta
     8101 tggtgtggta acctccgctc cggaaataca ctgcgctttc cgcgggctcg cgctaagcca
     8161 gggtactact tgcgtttact tctttgttcc cttgcaccga ggaagccagc tacgaagcgt
     8221 tactggaaaa cgcaggtgca tctagtgggg tcttagcgtc ttcgctttcc cgcaggagtc
     8281 ttcgtgtatt tcctccgcta agatttagct ttctgaatcg aattactgtt attcaattgt
     8341 taagctgatt gattggagcg cagggaagtc gactccagcg ggaaaagcaa cggctgaaga
     8401 tcccgcagga agccgggctt gcttccgagg aagctgaagc gttgcccgcg gaaagcgact
     8461 gcccgtagcg aaaatcggga attgctatta cgtcgcagtt tatatatttt atgaaaaaca
     8521 acaatctttg agaaaacagc ctaaaaaaat aaattgacat gttattcgat ttcgattaac
     8581 attgtcctca gcatgaataa agtctatctt attaatagcc gttgagacga ggggtcgaag
     8641 aaacggtggc aaaccaatct ggatcaaaat ccgaatatgg tgcccaacct gagcacagag
     8701 cattccggtt ctgtgaacaa taagaggata agcagctgat cttaatcgaa gctttcctta
     8761 ggttgtagga gagctttttt tgtgcctaaa aaaggaaatt tttaggaggt tttcgaattg
     8821 gcagagaagg ttttatttac ttctgaatct gtatcggaag gacatccgga taaaatagca
     8881 gatcagattt ctgatgctgt tctggatgca gcacttgagc aggatccttt ttccagggtg
     8941 gcctgcgaag tattcaacac aaccaatacc atcattgtgg gtggagaaat tacaactaca
     9001 gcgactttgg atattgaaaa aatagcacgt gacacattga tcgaagttgg ttatacgaat
     9061 gatcagttcg gaattgatgg acacacttgc gatgtacagg ttctcgtcca cacacaatca
     9121 ccagatattg ccatgggggt aaattcatca agcgatacga aggaaattgg agctggtgat
     9181 caaggtatca tgttcggttt tgcaacaaat gaaacagata gtctgatgcc attaccgatt
     9241 gaaatggcac ataccttggt aaaaaaagct tcctctttaa gaaaaagcgg cagcttcaaa
     9301 tgggcacgtc ccgatatgaa atcacaagta acgattgatt atacggtccc tgatgcgcct
     9361 agaatagata cgattttgat gtccattcag catgatgggg attttaataa aaagaatttg
     9421 agaaatatgt tatcgaaaat atcatacagg aaacggcaag ggaatttcgt ttaaacaaaa
     9481 catttcgtac tttaatcaac ccaacaggaa gattcgtggt aggcggtccg catggtgatg
     9541 cgggattaac tggacgtaaa attattgtcg acacgtacgg aggagctgcc agacatggcg
     9601 gtggggcttt ttctggtaaa gattgtacga aagtcgatcg gtcagcggca tatgctgcac
     9661 gttatgtagc taagaatatt gttgcagctg gttttgccgg gaaatgtgag attcagttat
     9721 cctatgccat tggagtaagt gaaccgatca gcatttcact tgaaacgttt catacggaaa
     9781 aggtgacaca tgagcaattg ctacttgcca tacgaaaagt ttttaactta acgccaagcg
     9841 gtatcattga catgctgaac ctccgcaagc ctcgttacaa acaagttgcc gcatacgggc
     9901 actttggcag aagcgatctt gatcttcctt gggaaagaac cgataaggtg gaggaactac
     9961 atcaggcaat tgaaacggct gcatttgctg gagtcggaca atgatgaaca atgtccatga
    10021 ccttgttgcc agcaaaaaga cattgggaga acagaatgag atgcctttat ttgctgcatt
    10081 ggtacgttat gccgagcagg aggtcacacc gtttgacgta ccaggacata aaatgggggc
    10141 gcaaatgaat cccttaaaag aggctctagg ggaaatgacc ttgcgtatgg atgtgaattc
    10201 aatggaagaa cttgatctat taagccatcc gcaatccgtc attaagaaag cacagaagtt
    10261 ggcagcagcc gcttttggtg cagaccatgc cttttttctc gtcaatggta caacaatcgg
    10321 gatcctggca atgatcattg ctgtttgtaa accgggagaa gcaatgctgg tgcctcgtaa
    10381 tgcccataag tcggtaatgg aagggattat tctcagtggg gcaaatccga tattcattca
    10441 gccggaaatc gattaccatt ttggcatatc ccataatgtt tcagtatcga aggttaaaaa
    10501 agcaatcgac atgcatccag aagcaaaagt gatgctgctt acgtatccga cctattttgg
    10561 ttccatgaca gatctaagtg aaatctgccg tcttgctcac gaaaggaata taacggttat
    10621 tgttgacgcg gcacatggtg ctcaccttgg ttttatgcct ggtgatctgg ctgatccaat
    10681 atcggctggg gcagatgcag caacaatcag catgcataag accggcggtt cgttgacgca
    10741 aagctcatta ctgcttttgc agaatgatag aatcccgcct caaaagattc agcaggcatt
    10801 gaacatgctg caaacaacaa gtgcgaatta cttgctgatg agctcgttgg atgtagcgag
    10861 aagagagcta gtcctatatg gcagtaagca atacgacgaa ttaaagccaa ttgttgaaga
    10921 ggcaatcaaa actatcgaat gtgcatctaa ttttgaagtt ttaaaagcat cttatgtgaa
    10981 gaatcaatac aatcaagcat atgactggac aaaattagtc atccgagtga atgggatagg
    11041 tttaacagga tttgaagttt ataaactatt aaaagaaaaa tataacattc aagtggaatt
    11101 ggcagaaggc tatgtcatta tggcagtaat aaccagttcc gactcaaaag aatcgattga
    11161 tagacttgtt tttgccttaa aagaaattga aagacggttt ggaaagcaga tggtggtcat
    11221 gtccacgaat gtaacggccg atctggtgaa tgaacttgtt ttgaatccac gcgatgcctt
    11281 ctacgcagaa caggaatcga ttgcaatcga agacgcagcc ggcaggatca gcggcgatac
    11341 attgatgatc tatccgcctg gaataccttt agtcattccc ggagagatca tttcaaagga
    11401 agtcattcaa cagtatcatt attattgtga gaccttggga aatgtattga cggaaaccaa
    11461 agaagcggat catattacag ttataaagga gaatgtatag atgggattgg aaattacagc
    11521 attagggaga catgtgttga ttgaatatta tggctgccca agcgaaatta ttgaagataa
    11581 cgccttgatt gagaagttta tgcgcggagc ggcagactat tctggtgcaa ctatagtgga
    11641 gtcggttttc catcatttca atccatatgg agtttccgga gccgtgatta ttgctgaatc
    11701 gcatttgaca atccacacat ggccggaata tggttttgct tctgttgatg tctacacttg
    11761 cggtgattct gtgaatcctt ggaaagcggc agactatctt tctgagaaac tgcaggccaa
    11821 aaaaacagaa tcatttgaag tgcctcgtgg aatggtagat aaaatccgtc aatttgcaga
    11881 gcaggaaatc gaagaagtaa aagtcaaaca agcattagaa ggtgttaatt aaatgaactg
    11941 gtatacggaa caatggagcg gtgaaactaa attttccatc gcatatgata aacaattata
    12001 tagtgaaaaa accccgtttc agcagattga tttttataag ggtaatgagt tcggcacttt
    12061 tttcacgctt gatggcttga tgatggtgaa tgaaaaggat gaattcatct atcatgatat
    12121 gattgtccac ccggcatttg ccacgaaccc tggaattaaa agtgtcctga tcattggcgg
    12181 aggagatggc ggaacggccc gcgaagtatt acgttaccgg atagtggaaa aagtggtcat
    12241 ggctgaaatt gatgagcagg tcttccgtct gtgccaggaa tatttgccga ttactgcaag
    12301 tggtatagaa gaagatagcc ggatggagct gcgttttgag gatggccttg catatgtaag
    12361 aaatacaccc gatcagtcct ttgatttgat tcttgtagac tctacagatc ctatttccgt
    12421 tggagaagga ctcttcacaa cggagttcta taaggaatgc tatcgtgtac tgaataaaca
    12481 tggcatcttg ataaatcagc atgaatcacc atatttcgcc gaatatgcag ccaacatgaa
    12541 aaaggcccat caaaagatta aagcaatatt tccaattaca aatgtttacc aatatcatat
    12601 gccgacatac ccttctggcc attggctgtt cggatttgct tccaagtcct atgatccact
    12661 gcaggatttg caagcagaag cgtggaataa atttggcctg gagacgaaat attataacac
    12721 ggacttgcac cggggagcat ttgctttgcc gaattacgtc aaggaggcac ttgtacgcga
    12781 tgaataaatc attgaatcta agtactttta taggctgtga aagttcttat aaagaagcag
    12841 aaatagtcct gtttggtgtc ccttttgacg gtacaacgag ttttcggccg gggacacggt
    12901 ttgccatgca ggaaatcaga ccagattcat ttggtcttga aacgtattcc ccttatttgg
    12961 ataaggatct ggaagatgca gcaatctttg atggcggtga cttggaattg ccgcttggaa
    13021 atacggccaa agcaatggat cagatccatg cgtatactcg ggaagtattg caagacggaa
    13081 aaaaattcct gatggtgggt ggagagcatt tggtgagtct gccgactatt caagcagcat
    13141 atgaaaagta tccagacttg catttgattc atatcgacgc ccatacggat ttgcgagagg
    13201 actatttggg tgaaaagctc tcccatgcat cggttattcg tcgctgccat gaatttcttg
    13261 gagacggaag gatttttcag tttggaattc gttccggtct gaaggaagaa tttgaatggg
    13321 ctgggaccca tacgtatctg gagcgttttt ctcttgcaac attaatggaa aagatacaag
    13381 agctaaaaga tgtgccagtc tatatcacga ttgatctgga tgttcttgac ccgggcatat
    13441 tcccgggaac tggaaccccg gaaccgggcg gcataaccta ccgggaactg ttgaaagcga
    13501 tcgaacagat gcagcagctg aatcagattg tggctgccga tgtcgttgaa ttgtctccac
    13561 catacgatcc atcaggggca tcgactgcta ttgcgtgcaa aacaataagg gaactcttac
    13621 tgacacttac agcataggac aaaaagtcca ccgtttgact gaatgatggt ggactttttg
    13681 gttcaaaaac gccgtatgat aatagaaata ccaagaaccg aagaactggg catatttcca
    13741 ccagaagtat atatacttac aattagaaat gaagatacta aatacaggct gctattttcc
    13801 cggcagttac aacaaaccct cgggattttt agagaatagc ttaagtttaa ttaaggcgga
    13861 atacggtaat ggaaaaataa gatgcgtatt gtccagaaaa tatcacaaag aagataaaca
    13921 caaaacgatt ggtcactatg catttctggc cgaccttatt ttttaaggag gactttcttt
    13981 taatgacaaa aacgattttt gaaattgaaa cgctaatcaa caatcgaata aaagaaatac
    14041 agaatatggt agcagatgat ccatatcggc tgcattatca tttgatgcct caaatcggac
    14101 tgttgaacga tccgaatggt tttgcctatt acaaggggca atatcacatt ttttatcaat
    14161 ggaatccttt tgaaacaaaa catgggatca agtattgggg acattatgtt tcggatgatc
    14221 ttgtacattg gaaagagctc ccgattgccc tggcacccga tcaatggtat gacataaatg
    14281 gctgctattc tggaagtgcg gttgttcacg aagacaagct gtatttattt tatacaggaa
    14341 atgttatgga tgaggaagga aacagagaag cctatcagtg tatagctgtt tctgaggatg
    14401 gcatcaattt tcagaaaaaa ggacccatca ttcatgtgcc tgaaggctat acacctcatt
    14461 tccgcgaccc aaaggtttat tataaagcag ggaaatggta tatggtaatt ggtgcacaga
    14521 cttcagaagg gaaaggggaa gcagtattat atacttctcc tgaccttgaa agctggagct
    14581 ttcagggccc gcttgcagga agcgggcata atggactcgg cgatttcggc tatatgtggg
    14641 aatgcccgga cttatttgag ctcgacggcc atgaagtcct aattatctgc ccacagggcc
    14701 taactccaag aggctacgaa tttaataata tatttcatgc aggttacctt gcaggggaag
    14761 tagattatca taatgtatcg ttccagcatg gccctttcac agaattggat agaggttttg
    14821 acttctatgc ccctcagacg atgatggatt ccaagggaag aagacttctg ataggctgga
    14881 tgggaaatgc agaggaggga gagtcaattc atcccactac aagatatgag tggatacaca
    14941 ctctgacact tccacgacag ctggaatgga aaaatggcaa actattgcag taccctgtgg
    15001 tggaacttga aagcttgcgt gaaaatcaaa tagagtatga ggacgtacct gtgcatgaag
    15061 gtgaactgtc attgcctaac attcaaggga gtgtttttga attggaagtg actatcaaat
    15121 ctggaaatcc ggatgttttc tccattaaaa tcgggcaaaa taatcaatta agctatgatc
    15181 aatcgactaa caccttttcc ttgcagcgga tggaccttgc tgacaaccat gcattcgaga
    15241 aaaggtattg tgtgctggag gaacttagga gcattcggct ttataaagac acttcatcaa
    15301 ttgaagtgtt tgtgaatgag ggagaagaag tattctcagc aaggattttt gactatccga
    15361 atgagcagga tattaacttt tatgccaatg gcagtctcac aatggatgta aagaaatggg
    15421 agttaaaaaa attaaagtgc ctttaacacg aaccatgtga acaagacaat ggaaatataa
    15481 aaaaatcaaa gaaggacaga ttcgttaatc cgcagaatct gtcctctttt attttgattt
    15541 ccctaattta ctaactattc catttattga tcaaacgttt gatcaataaa aaatataatc
    15601 tctttcatga gcaaaactca tgtttatagt ataattattt catattttat cattgactaa
    15661 ttgtcagggg agcgtgacca atgcaaacca atttatattt tgtaaggcat gcacattcta
    15721 tctatacgcc agatgagata aacagaccgt tgtctgaaag tggcattgct gatgtaaaaa
    15781 gggtagctga gtgtttattc ggacagcgga tagacaccgt aatctcaagc ccatataaaa
    15841 gagccattca aacgattgag gcggttgccg aatcggttga taaagagata atagttatgg
    15901 aagattttag agaaagacaa ctgtctgaga caagcgttga cgatttccag ttcgctgttt
    15961 cgaaactttg gtccaatccg gcattttcct ggaagggcgg agagtctaat gacactgcgc
    16021 aagatagagg cataaaagct acttttgaag tgctggaaag gtatatgggc aagaatgtag
    16081 taattggtat gcatggtaat ttaatggttc tgattatgaa ttattttgat gacagatttg
    16141 attacacttt ctggagaaat ttgacaatgc ttgatgtcta taaattgaca ttcgaggcaa
    16201 ggaaactttt gtttgtcgag cgattatgga agcaagatta agacatacaa tctattcgtt
    16261 cagaaagatc aaatgaagca aaagcttatt gttaatatgg agcttacccg actattaatt
    16321 aaatgaaagt aaatgttttc cttatccatc tcacaataga tcaaaaagga tttcgaaatg
    16381 ccgccggatt gtacgccata ttcaaataga atagatattg actgcaggaa atcgaacttt
    16441 cattatggtg gataacgata tacggaattt tacgtgattg aagcccacgc atattcagag
    16501 aaagatttgc cagatgtctg aaggatggac tcgttacaac atttgccaga taggctgatt
    16561 gcgtactgcc tgcctttctc atgctattca aactctcaat catcctatcc gcagtcataa
    16621 tgcctaaccc atgtccaaaa aaggttccat cgcccataac aactgcgttt tctccacgcc
    16681 accatgaagc tgccgggtca aaatcgggat tgttgaaata tacgacatct ccaggcaaaa
    16741 aatgattcga atgcaggctt cttattccaa aatcagggtc gaaatgccag ctgtataaat
    16801 agagatcttg gaatagatca ttaaacagct gtaagccaat acttgttaaa agcgcatggt
    16861 aataaataat aacatttgcc acagcacatt caaatgcata taggtaactg tttcggtaaa
    16921 tatccagaat tgcttctgat ggcaatacat taggcttcag ctggaagcct cccgcatctg
    16981 tcaaatccca atacatcgga ttacatcttg aatttgcaaa attggcgaat tgcatatcac
    17041 tctgctccat ggctcttgca ctagctatta tattttttcg gagttcaatt tcaaacatta
    17101 attcatcttt ggactgataa gcgtaaaccg ttacgctttc tttcatgttt cggataatga
    17161 tactttcaat gctgccaggg gcaaacaaat tgtctccgct aaagctgatt cctgaaactt
    17221 caatcattta attccctcac tctcaccatt aaaggatcac ttgtgttact acccaatcta
    17281 ttcagttgtc accaaaatgt taaagggccg gaatatagac caattatgaa atgttgtctt
    17341 gattggcgcg acgaaaatgc tgatattttg attgaatatg ctgatgttca cggggaaaat
    17401 gctgatgttc acaaataaat ggctgatgtt cacaagaaaa atgctgatgt tcatatttgg
    17461 caccctacac ttgttccaga cttcctgatt acaatcagaa taacgcctgc taatcatcct
    17521 gtcagtataa aaattttgaa acctttaagt tatgcaatcg tataataagt aaccattgat
    17581 ttatgtaaag gggaatgtgc aatgaaaaga aaacagcagc tgtatccact aatggcagga
    17641 ctggctggat tcggattgac gtttatcgtt acgttgctga ttgaatcaac ccaccctttt
    17701 ttggctagtc tggtgctggg ttttataata tttgaaataa gcttttatta ctttcatagc
    17761 gaagaaaagc ggattaatga actatagcta gctggcttaa tcaatgataa tttcgattat
    17821 tattcattaa gcctattttg tccgcggatt tgcaaataaa tgatagattc aggtggtctt
    17881 atgaacagta ctgtaccgaa aagaatacat attatcggct ctgtcggaag cggcaaaact
    17941 actttggcaa aagaattatc tattatgctg gagataccat attacgaatt ggataatgtg
    18001 gtttggagaa ggtgtaattc cggggacaaa agaagatctg aagaagaaag agatgagcac
    18061 ctatttcgaa tcatacaatc tcctagctgg ataatggaag gggtccataa tgaagattgg
    18121 gtaagcaata gttttcatca agcagatctg attattttct tggatacaag gtattcttta
    18181 agaacttatc ggattatcaa acggtttttc aaacaaaaac tacggctaga gaaatcgaat
    18241 tatagaccaa cattagcaat attttttaaa atgtttaaat ggaaccgaca ttttgaagag
    18301 gtgggaaaag ttaatttctt cagcaagtat ggcatgctcc atgacaagac agctgttatt
    18361 accaataata acggtataac ggaactcttc aaagcaaata atcgatagtt taaacaaagg
    18421 gggaagattg tgtgaacgaa aaagaggctc ccgaacagaa aagggaaaga ttaaggcaag
    18481 aagaattgaa aaaaaatcca attggtaatg cgggcgatgc ctttaacagt gctgatagcg
    18541 gcaatcttgc tgatctggta ggaggtttgg gctggaaagg tactgggtta attattgctg
    18601 caataatagt tggattgctc ttatactctc tcttctttcg ataaggaata aggaaatgta
    18661 agcagaggtt tcttttttcg ttgagaataa tctatagaaa tatagtcctg gcaactgtcc
    18721 tatggtatga gccagaatat tttaatgata ggcactttaa atttagcctt gaccttttat
    18781 tttcgataac atagaattaa ttcaatatca aatgagcgat gatgaagaat agtaggctat
    18841 aagaacggtc aagagagctg gtggttggtg agaaccagta cggaattatt gctgaatggg
    18901 cttttgagct tctgaactga aagagatgag taggttcagc ggaatgtctt accgttaaaa
    18961 gagaccaagt atcgaagcaa gtccaagtac tgtttcggta tggctaagtg cgtttacata
    19021 tgtaaacgaa taaaggtggc accacgggtt actcgtcctt atttttggga tgggtaatcc
    19081 ttttttgtat agattttatc aatggagggg tagtatgaaa aagacgattt tgactggaat
    19141 aaagcctacg ggacagattc atttaggtaa ttatattgga gccattaagc cggcattgga
    19201 gcttgctgta gaggaagatt attcgccaat atatttcgtg gctgattatc atggcctaac
    19261 taaaaccatt gactctgaag acttccgctc cttctcctat ggaatagctg ctgcttggtt
    19321 ggctcttgga cttaatccgg agaaaacgat tttttataga caatccgatg tcccggagat
    19381 atttgaattg aattggatat tgagctgcct tgcatccaaa ggattgatga atagggccca
    19441 tgcctataaa gccattgcag ataacaatag aaaagcgcaa aaggataaag attacggggt
    19501 caatatgggc ttatacaact atcctatatt gatggcagcg gatattttaa tgttccggac
    19561 aggaattgtt cctgttggaa aggaccagat acagcatgta gaaatagcca gggatattgc
    19621 cgaaagtttc aaccgtaagt acggagaaac atttgtttta ccagattata atattcagga
    19681 agatactgca gttttgccgg gattggatgg caggaaaatg agtaaaagct atcataatac
    19741 gattccaatt tttagtgagc aggcgaaatt gcgaaagcta ataaataaaa tcaaaacgga
    19801 ttcgttgccg ccagaggttc cgaaagatcc ggataaatca actattttta tgctctataa
    19861 ggaatttgca cttccggcag aagtcgaaag tatgagacag caatttttga caggtgtagg
    19921 ctggggagaa gcgaaagggc agttattcca tgttatgaat cgatttttgg aacagccgcg
    19981 ggagagatat aaagaactta tggaaaatcc ggaaacaatt gacaaggtat taaaagaagg
    20041 agcagataaa gcgagagaaa tgagtgttcc attcttaaaa gaaattaagc gtaaaatagg
    20101 attttattca taagttcagc aggaaccggg ttctaaattg tgattagatt tcagtctatg
    20161 aaagtgactt atcggaaggc gcagaagaat gacctttcca tccggcacgg ctctaacaac
    20221 taaaataagt gattgacaaa gacgtaaaat gggagtattt tgtgattaat tgaagctgtt
    20281 ttctaaagga ttgttatata cgacggataa tcaaaactgt gagttgaata gtagcccagt
    20341 taatcaatgc tatcagtaat tgtccattat tttacaaatg acggtatggt tgtctgcttc
    20401 gcttttagcg gattttcact caccatacga aaagagcctt cattaactaa aaaattatct
    20461 gagcctttat tcgcttaatc tatttgagcg ggggaaccat atttgataga tataatctat
    20521 ctggggtgaa tcttacctga gtaagaaggg atactctccg tccctaatcc gacagctaac
    20581 ctcgtaggcg ttgaatagtt ttcgagagaa gggtcaatgg caaaagccaa aagaccaatc
    20641 ttatttctga tggtcttttt ctttttggaa tttacttaga aaagaggatg tgtattggaa
    20701 aagcaagtag tcgtaatagg gcttggcaga ttcggaagaa gtgtttgtaa acaattgcat
    20761 gagctgggtc atgaagtact ggccattgat aaaaaagaag agagagttaa acttgcttct
    20821 aattattcct attatgctgt cgttgcaaat gcttcagacg aaagcgtact aaagaactat
    20881 ggagtaagaa acttcgatca cgccatcatt gcgataggag acagtatcga atccagcatt
    20941 ctgtgtacct tgattctcaa ggatatgggg gtaagcaatg tctgggttaa agcaagagat
    21001 ctgcatcatc agaagatact tgaaaaggtt ggagcagatc ggattataca gccagaaaag
    21061 gaaatgggtg tgcgaattgc caatcaactc gattctggaa aactattaga ttatatagag
    21121 ctttccaagg actatagcat tgttgaatta atcgcaacta aaaaattgtc tgggaagtct
    21181 ttgattcaat tggatatccg tgcaaagtat ggttgtacaa tacttgccat taaacaggat
    21241 gaaacggtca atgtttctcc tatgccggaa gatatcattt caaaagggga tgtattggtt
    21301 gtgatgggcc aagtaaatga cttgaaacgt tttgaagata agggattcta atgaaaatat
    21361 ctttaaagag atttaagctt acctacttat caacgattcg acttatcgtt ttattttata
    21421 ttgtcgctgt catattttca gtagtattat tgggtctgcc ttttcttcat catgcaggtg
    21481 aagaactatc gcttattgac ctcatgttca ctgcagtgag tgccatcagt gttacgggac
    21541 ttgctgttgt ttccactcct gaaacattta atactgcagg taagattgcg cttacctttg
    21601 tgatgcaatt tggcggtatt ggaattatga ccctcggaac gatagtttgg gtaatacttg
    21661 ggaaaaaaat aggtttgcga ggaagacagc taattcaaat agatcataac cgagcttcct
    21721 tagcgggctc cgttaagcta attttaaaga tcctaaaaac cattcttcta attgaattga
    21781 tcggtactgt tatactgagt gcctatttca tgaattattt tgattcatgg caagaatgtt
    21841 tactgcaagg atattttggt gcagtaagtg ctactacaaa tgctggattt gatataacgg
    21901 ggtcatcctt agagctcttt gcagacgatt atttcgttca atttgtaaat attatactat
    21961 tgacattagg agctatcgga tttccggtgt taattgaatt gcaaaattac atgcgaggag
    22021 accatttgga tggtaatcca agaaatagct tttccctgtt tacaaagctg accacactta
    22081 ctttttttgc gcttatcgca gctggtgcca ttctaatcgt tctattggaa tggaatgggt
    22141 ttatggctga taaggtatgg cacgaaaggc tattttttag tcttttccaa tctgtgacga
    22201 cgagaaatgg agggcttgct accatggacg taggtgagtt ttcttcaccc acacttatcg
    22261 tgttgtgctt tctcatgttt atcggtgcct cgccaagcag tgtagggggc ggcataagaa
    22321 caactacttt cgctataatg ctgcttgcca tttataattt tgccaaagga agaactggaa
    22381 ttaaggtatt tggacgggaa ttagagcagg aagatgttat tggttcattt atggttatta
    22441 caactgcttc catgttatgt atgattgcaa ttattacact tacttatatt gaaccatttt
    22501 ccctgatcga gattgcattt gaagtttcat cagcattcgg aacaacaggt ttatctctgg
    22561 ggattactcc ggaattaagt actgctggaa aatgcattat tatattttta atgtttgtgg
    22621 gcagaatagg aattttttca ttcttattcc taataagagg taaagaaaca aaagaaaatt
    22681 atcattatcc aaaggaaaag gtaattattg ggtaatttgt agtattgaaa gcaagatgaa
    22741 tcgccgcaaa ggagtggacc tcatgaaacc ttttatactt agtggatcaa ttctcatatt
    22801 ggccggctta attgctgcta cagtgatcta tcatcaaaat tccagagaaa tcacatatcc
    22861 tcaattggga caggccggaa atgtacaaga taatcaagtg tccgatagtg aaccggaagg
    22921 accgcagacc gagcagctgc aaccagtaaa tcgtaatgag gcgattactt acactttgca
    22981 gaacaacgaa ctaaagattt ctttcaataa tggaaatgac tggattagcg tccctgttga
    23041 aaaagatgaa ctatttggcg gggaatataa tggaaacggg caggaattga ttgaaaacag
    23101 ctacattctt agagaagatc tggctgcgtt cttatatgcg gacggcgata actgggagag
    23161 tcaaagaata atgttagtct atacgcggga taaaggacag tcctgggagg agtcagttgt
    23221 tatagaacca tatcctggta ttcgtttcag aaaaattgat tttctgaatg agaattttgg
    23281 ctatgtgatt atttctggtg gccggagcat gtcgcaagaa ggttcaagtg tcttcttaac
    23341 agacgacggc ggccaaagtt ggagagaaac gaacagctcc ggagtaacga gactaatttc
    23401 ttatggggga tttatcgatg aaacgacagg gttcttatct tttgggacta ttaatccaga
    23461 ggaacctgat ctgcatgtta cccaagacgg aggtaataca tggacgaaag cgatcgttaa
    23521 cgttccagag gagtatcagc agatctttgt agcagcggaa acgccagtaa tagaggatga
    23581 ccatttgaca gtactggtta atcaaggccc caatggggat tatgagggcg gactcgt
//
