LOCUS       c00030_NZ_CBYM..       15768 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CBYM010000030.1 Clostridium saudiense strain JCC, whole genome
            shotgun sequence.
ACCESSION   NZ_CBYM010000030
VERSION     NZ_CBYM010000030
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:06:27
            Original ID  :: NZ_CBYM010000030.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 25188
            Orig. end    :: 40956
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15768
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[35188:38728](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13540)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15768
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15768
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(964..1719)
                     /locus_tag="ctg30_29"
                     /transl_table=11
                     /translation="MIEVKNISKAYGNKKVVDNVSLNIQEGKITSFIGPNGAGKSTLLS
                     IMSRLLKRDSGEVLLDGKDILSWDNKELAKKIAILRQSNNINIRLTIKELVSFGRFPHS
                     QGNLKEEDYKYIDEAINYMQLKEFEDRYLDELSGGQRQRAYIAMVIAQNSDYIFLDEPL
                     NNLDMKHSVEIMKTLRKLCDELNKTVVIVIHDINFASCYSDYIVALKDGKLVKNGVTEE
                     TIQKEELENIYEIDFHIENINNRNICVYF"
     CDS             complement(1716..2672)
                     /locus_tag="ctg30_30"
                     /transl_table=11
                     /translation="MKTKDKKSIIILTVLALILITSFLFIGVNSVNFKYALYRRIPKIY
                     AMILTGAAIGFSSLIFQTVTNNRILTPSILGIDSLYVLLQTTIVFLLGSSSAIISNGNI
                     NFIITIVSMLLFSSLIYKFIFKKGSKNIFTLLLVGVVCGTLFESLTTFMQVLIDPVEFQ
                     VVQDKMQASFNNINTDLLFVSSIVIILCIGYVYDYLKILDVMSLGRDEAINLGVDYDKM
                     VKKMLIVVVLLTSVATALVGPITFLGLLVVNIARQVISSYKHSTLGIGTILISIVALIG
                     GQLFVEQVMNFGVSVSVIINFIGGIYFIYLVMKERNR"
     CDS             complement(2662..3615)
                     /locus_tag="ctg30_31"
                     /transl_table=11
                     /translation="MKKRYLFIVLIILCIASIFIGVTNININDILTFNIDKIEILLISR
                     LPRLIAIIVAGVGLSISGLIMQQISKNKFVSPTTAATADFAKLGILFCIMIIPGATIMQ
                     KMIVSFVFAGLGTVLFMKMIKAIKIKNIVFVPLIGMMLGKIVGSITTFFAYKYDLVQNI
                     SSWMEGDMSLIMKGSYELLYLSVPMVIIAFLYANKFTIVGMGEDFAINLGLNYNFVINV
                     GLAIVSLICAVTIITVGNIPFLGLIIPNIVSLYSGDNLKKTLYHTALLGPIFLLACDIL
                     GRIIIFPFEMSISLTVGVIGSIIFLYMIVRGTKNED"
     CDS             4001..4180
                     /locus_tag="ctg30_32"
                     /transl_table=11
                     /translation="MAQKLVPEAKNGLSKFKNEVASEMGVPFTDYNGNLTSKQCGSVGG
                     EMVKRMVEQYEKGI"
     CDS             4631..6862
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PFL_acetate2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_33"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-46, bitscore:
                     149.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.5e-295, bitscore:
                     971.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWNDFKTGSWTKSIDVRNFIQTNYTPYEGDDSFLAGATEDTN
                     KLWAEVSELFKKERENGGVLDVDTETISGINEYKPGYIDQAFEKIVGVQTDAPLKRAVM
                     PYGGIRMAENAAKAYGYEVSPRISEIFSKYRKTHNQGVFDAYTSEMRLARKSGVITGLP
                     DAYGRGRIIGDYRRVALYGVDRLIQDKEQQKLSLEVKTIDEDVIRLREEISDQILALKE
                     LKGLAASYGFDISQPATNAKEAIQWLYFGFLGAIKDQNGAAMSLGRTSTFLDIYIERDL
                     RNGVITEEEAQELMDHFVMKLRLVKFLRTPEYNDLFSGDPTWVTESIGGMGLDGRTLVT
                     KNSFRVLNTLYTLGPSPEPNLTVLWSTRLPQGFKDFCSKVSIDTSSVQYENDDLMAPYW
                     GDDYAIACCVSAMRVGKQMQFFGARVNLAKTLLYAINGGKDEKYGMQVGPKTAPLTGEY
                     LDYNEVMDRFDVMTDWLANLYVNTLNVIHYMHDKYSYEKLQMALHDRDVFRTMACGIAG
                     LSVCADSISAIKYAKVKPIRNEEGIAVDFEVEGDFPKYGNDDDRVDEIAAWLVESMMNK
                     IRQNKTYRNAYHTQSVLTITSNVVYGKKTGTTPCGRKAGEPFAPGANPMHGRDCSGSLA
                     SLNSVAKIPYEHSQDGVSNTFSIVPDALGKTPENRIHNLGTMMDGYFSQGAQHLNVNVF
                     NRETLLDAMDHPEEYPQLTIRVSGYAVNFIKLTREQQLDVINRTFHKSM"
     CDS             complement(6916..7752)
                     /locus_tag="ctg30_34"
                     /transl_table=11
                     /translation="MEIIIAIAMLTGVFCYYQNNKIVITNIKLKQKINNKVRIAQISDL
                     HSKEFGKNNYILYKKIIEQKPDIIVATGDLIDSSMKKLDEIIEFCSSINKDIPMYYILG
                     NNEMRCSRVSEIVEKLKKNKICVLENEIESIEVKGNKINILGLEEKRIDEGELFYSKVN
                     SRYGTENIEKIFSRLERLDGIKIVLSHYPENFEYVEEGAYSKYNFDIMFSGHAHGGQFI
                     LPGIGGIFAPGQGLFPKYYKGVYGEKNKLIVSRGLGNSGFPLRLFNRPDLVIVDLI"
     CDS             complement(7934..8401)
                     /locus_tag="ctg30_35"
                     /transl_table=11
                     /translation="MVKVFGIGNILLKDDGIGVRLARNIKRRVDKDNINEIEVFIGETD
                     YLYCLENINDDEFIIILDSTYFGINPGEITFKKLEECDKLISKEITAHETSLLSLVRLE
                     KTNVNGYFIGIEIDSIEYSLELSNILQKRFNSIYDEVYEFIVKIAKELYFL"
     CDS             complement(8410..8640)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NiFeSe_Hases"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_36"
                     /sec_met_domain="NiFeSe_Hases (E-value: 2.5e-26, bitscore:
                     84.0, seeds: 162, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISNYTLIPPSAWNFSPTDRKGLKGTVEQALIGAEINDINAPVEI
                     GRIVRSFDPCLNCAVHVTSNRHKPINIIINS"
     CDS             complement(8641..8934)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NiFeSe_Hases"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_37"
                     /sec_met_domain="NiFeSe_Hases (E-value: 3e-15, bitscore:
                     47.5, seeds: 162, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVMCNKGINMTTIRIDPVTRISGLLNIEVQVENNKIVDAKVSG
                     SQFRGFEKMFEGRPPFDIIRLVPRVCGICSTHHAITSVRAFENAMNITPDLN"
     CDS             complement(9029..9868)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_q6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_38"
                     /sec_met_domain="Oxidored_q6 (E-value: 2.1e-27, bitscore:
                     87.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIFKSDKYIIPIEEIDFWENRIFDKDTKDQKKNKLAMNMINNAI
                     DNVENNRVKKINAIWLETSGCFGEVISLLNSEDPNLIYMLEKFVDMKYFGSIQGDQGEE
                     AYKNIIDNLDTEYIFIVSGAIPTRDNGLYTTVATYKGEKITAMKAVSDISKNARIIITV
                     GTCACFGGPTAAKPNLSKALSVSEFLKRTDIIKIPGCPANPVWVAGILGYIASGGIPEL
                     DSNGRPLVYYDTLIHDICPRRKFFDQGIFAKKFGEKECMFKLGCRGTVTYAYCPVSR"
     CDS             complement(10001..13540)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_39"
                     /sec_met_domain="PFOR_II (E-value: 1.4e-18, bitscore: 58.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.9e-80, bitscore: 259.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.3e-37, bitscore: 120.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.2e-11, bitscore:
                     34.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 4e-11, bitscore: 35.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.3e-08, bitscore: 24.7,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00014, bitscore: 13.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 7.6e-27, bitscore: 84.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKRMMTIDGNTAAAHVAYAFTDVAAIFPITPSTTMAEVVDEWAA
                     QGKKNIFGQTVNVVEMQSEAGAAGTFHGSLQAGALTTTFTASQGLLLMLPNMYKVAGEL
                     LPGVFHVSARAIASQALSIFGDHQDVMAARMTGCVMLAAGSVQEVADLAPVSHLSAIKG
                     RLPFVNFFDGFRTSHEIQKVEVLDYEDYAEMLDREALKEFRSRALTPNNPVTRGTAQNS
                     DIYFQTREASNKFYNDIIPIVEEYMAKMEEKTGRSYGLFNYYGAEDAKEIIVAMGSVTE
                     AIEETIDELNARGEKYGLVKVHLFRPFSVEHLLKVIPQSVEKICVIDRTKEPGCNGEPL
                     YLDVCSAFYGKENAPKIVGGRYGLASKDVTPSDIKAVFDNLKKENSKNFFTVGIEDDVT
                     FTSIPVEDELRIATPGTVRCKFWGLGSDGTVGANKQAIKIIGENTDKYVQAYFAYDSKK
                     SGGVTMSHLRFGDTPIRSTYLIDEADYIACHVQAYVNQYDLLKGLKKGGNFVLNTIWNE
                     EEIERKLPAKMKRYIAENEINFYTVNATKIASEIGLGRRINMIMQSAFFKLAEIIPQEE
                     ATEYLKASIKKAYGKKGDKVVNMNYEAVEAGMNSLVKINVPESWKTATEEAKVETKEVT
                     DFVKNIMNPMNALEGDKLPVSAFNGLEDGTFPAGTAAYEKRGVATDVPEWNMSKCIQCN
                     QCAFVCPHACIRPVLVTDEELAKAPAGFETKKATGKTLAGLNYRIQVSTLDCTGCNNCV
                     DICPAPGKALEMKPLGTQVETEVANWDFSVSKEVSNKEHLTPGKTVKDSQFKQPLIEFS
                     GACAGCGETPYIKLVTQLFGDRMMIANATGCSSIWGGSAPSTPYTKNHEGKGPAWANSL
                     FEDNAEFGYGMFLAADQMRKKIASNMESLISMDIAEEYKEVFKNWLENKDNGELSKVHS
                     REVEAILAENNIENEEAKVLVEEIKERADFLVKRSQWILGGDGWAYDIGYGGLDHVLAS
                     GQDVNVLVFDTEIYSNTGGQSSKSTPAAAMAKLAASGKKTKKKDLGRMMMSYGNVYVAQ
                     VAIGADKNQVVKAMLEAEAHNGPSIIIAYSTCISHGLKKGMGFSIRNMDEAVKAGYWHL
                     YRYNPELKEQGKNPFSLDSKEPQGSFRDFIMDQVRYSAIAKQFPEQAEELFQMTEEHAR
                     QKYAELKKLAEQE"
     CDS             13974..14339
                     /locus_tag="ctg30_40"
                     /transl_table=11
                     /translation="MNKILTFHNDCRLNDRCAKYETCPMILVHKILSGKWKILILWYLS
                     NDTLRFSELKRKLPGTTQKMLTNQLRSLEEDNLIFRKVYPVVPPKVEYGLTDIGKKIIP
                     LLESMYSYGVEYSNTKN"
     CDS             14549..15760
                     /locus_tag="ctg30_41"
                     /transl_table=11
                     /translation="MSNTFKITEDLFWVGALDPNLRIFDIIMETKFGTSYNSYLLKGSD
                     GIALFETVKEKFFDEHLDKIRSIVNLEDINYVVVNHTEPDHAGSVEKILEYAPNATVVG
                     STLAIKYLSEIINKPFKSKVVKDWETLSLGNKTLKFISAPQLHWPDTMYTYVIEDETLI
                     TCDSFGAHYCDERVLKSAIEDSKEDDYIEAYNYYFRMIMGPFKPFMLKALDKIKDLNLK
                     YICPGHGLVLDHTNIEKFVNLYREWCQPTKREKQSIVIPYVTAYGYTEEIAKEIKRGIE
                     ASNFDVDILMYNLVTADMNEVLNEINQCSGLLLGSPTLLSDTLPQIWTILSSLNPVIHK
                     GLPASCFGSYGWSGEALKNINERYKQLKFNVVCEPLGIVFRPSEENLKSAYDFGLEFAN
                     KVLK"
ORIGIN
        1 atctaaataa acaatatttc catttttata agcatctgtt ttttccatta attcattttc
       61 aaataattct tttgctgatg ttgttcctcc tgcaatagca gctctatcaa caacaaataa
      121 ataatctgga tttttttcta ctacatattc aaatgaagcc ttttgtccat gtgttgaccc
      181 ttcaattgtt gtgtcaactg gagtaacacc aaatccgtta tggattattc caaatcttga
      241 ttctgctcca taaacactaa atgcaccatc gttagctaat gcaataaggc cattaatacc
      301 tttttctgtt accttagtat ttaactcttg aatagattct ttaattgtag caagttcttt
      361 ttctacatcc ttttctttac caaaaacttc tcctaatata ttcatattag tttcaaatga
      421 ttctaaataa ttttcattat ttaagcttaa attgatagtt ggtgcaattt tatttaactc
      481 ttcataataa tcagcttgtc taccagaaat tactattaaa tctggagtta attcaaatat
      541 tttttccata tctggttctt ttaaagttcc tatacttgaa tattcttcac tagcatattt
      601 acttaaatat tctggaattc catcttgaac tacacctatt attccttcaa cacctaattt
      661 atctaatgaa tctaatatac cgtaatcaaa tactactact cttttaggat ttttattaac
      721 tgttgtttct cctgactcat gtgtaaccac taaagtttct ccttcagcat taccttcagc
      781 tccaacaaat ttagttatac caaatatacc taaaactata actaataaaa ctactattga
      841 taaaattgtt tttttcttca tccttaaaac actccttgtt tttaatattg atactcatta
      901 tcaatatatt tcttatttaa aggcaaattt aataatttgc cataaaatac acttctcttt
      961 ttattagaaa tatacacaaa tatttctgtt attaatattt tctatatgga agtcaatttc
     1021 atatatattt tctaactctt ccttttgtat agtttcttca gttacaccat ttttcacaag
     1081 tttaccatct tttaatgcaa caatgtaatc tgaatagcaa gaagcaaaat taatatcatg
     1141 tataactatt acaacggttt tatttaattc atcacaaagc tttcttaaag ttttcattat
     1201 ttctactgaa tgcttcatat ctaaattatt taatggctca tcaaggaata tataatcact
     1261 attttgagct attaccattg caatataagc cctttgtctt tgtccaccac tcaattcatc
     1321 taaatatcta tcttcaaatt ccttaagctg catataatta attgcttcat ctatatattt
     1381 ataatcttct tcttttaaat ttccttgtga atgaggaaat ctaccaaagc taactaactc
     1441 tttaattgtt aatctaatat taatattatt agattgtctt aatatagcta tttttttcgc
     1501 taattcttta ttatcccaac ttaaaatatc ttttccatct aataaaactt ctccagaatc
     1561 tcgctttaaa agtctactca ttattgaaag aagagtactt tttccagctc catttggacc
     1621 aatgaaagaa gttattttac cctcttgaat atttaaagat acattatcta ctactttttt
     1681 atttccatag gctttactta tattctttac ttctatcatc tatttctctc cttcattact
     1741 aagtaaatga aataaattcc tccaataaag ttaattatta cacttactga tacaccaaaa
     1801 ttcattactt gttcaacaaa taattgtcca cctatcaatg ctactatgct aattaatata
     1861 gttcctatgc ctaaggtact atgtttgtaa cttgatataa cctgccttgc tatatttact
     1921 acaagtagcc ctaaaaaagt tataggtcca actaatgcag ttgcaactga agttaataaa
     1981 actactacta ttaacatttt ctttaccatt ttgtcatagt ctactccaag atttatagct
     2041 tcatcccttc ctaatgacat aacatctagt atttttaaat aatcataaac atatcctata
     2101 catagtatta ttacaatact tgatacaaat aataaatcag tatttatatt attaaagcta
     2161 gcttgcattt tatcttgtac tacttgaaac tctactgggt ctataagaac ctgcataaat
     2221 gtagttaaac tttcaaataa agtaccgcat accacaccaa ctaataacaa tgtaaatata
     2281 tttttacttc cttttttaaa tataaattta tatattaaac ttgaaaataa aagcatagat
     2341 actattgtaa taatgaaatt tatatttcca ttgcttatta ttgcagatga tgatcctaat
     2401 aaaaacacta tagttgtttg taataataca tatagtgaat ctattcctaa tatactagga
     2461 gttaatattc tattgtttgt aactgtttgg aatattaatg atgaaaaacc gattgctgca
     2521 ccagttaata tcattgcata tattttagga attcttctat ataaagcata tttaaaatta
     2581 acactattta caccaataaa taaaaacgaa gttattaata ttagagctaa aactgttaaa
     2641 attattatac tctttttatc tttagtcttc attttttgtc ccccttacta tcatataaag
     2701 gaaaattata cttcctataa ctcctactgt taaactaatt gacatttcaa atgggaatat
     2761 tattattctt cctaaaatat cacaggcaag taagaatata ggccctaata aagctgtatg
     2821 atatagtgtt ttctttaaat tatctccact atataagctt actatattgg gaattataag
     2881 acctaagaaa ggtatattac caactgtaat tattgtaact gcacaaatta atgaaactat
     2941 tgctaagcct acattaatta caaagttgta atttaatcct aaattaattg caaagtcttc
     3001 ccccattcct acaatagtaa atttatttgc atataaaaat gctataataa ccataggaac
     3061 acttaagtat aataattcat aacttccttt cattattaaa gacatgtccc cttccatcca
     3121 tgatgaaata ttttgaacta aatcatattt atatgcaaag aatgtagtta ttgatccaac
     3181 aatttttcct agcatcatac ctattaaagg tacaaatact atattcttta ttttgattgc
     3241 ttttatcatt ttcataaata gtacagtgcc taatcctgca aaaacaaaag atactatcat
     3301 cttttgcata atcgttgctc ctggaattat cattatacaa aataaaattc ctagcttagc
     3361 gaaatctgct gttgctgctg ttgtaggaga aacaaatttg tttttactaa tttgctgcat
     3421 tattaaaccg ctaatactta atccaactcc tgctacgatt attgcaataa gccttggtaa
     3481 tctactaatt agtaatattt caatcttatc aatattaaaa gttaatatat cattaatatt
     3541 gatattagtt acccctataa atattgaagc aatacataat attattaata caataaataa
     3601 atatcttttc ttcatttgct ttcccccata ttgccttacc ttatctcaaa aaacaataaa
     3661 taattctatt tgaaattatt tattaattga tattaatttt catttatttc ttacacattt
     3721 tatcattcta ttcttctatt gtctaggtat tttttctatt ttttatattt tttattttct
     3781 ttaaaacttt tttagttaat tttgattttt ttctcattga tattgaatat tattacaatt
     3841 tagtaaaagc atattaatta aggtattcgt tatacagaaa taactttttt ggtactattc
     3901 cctacttttt tatagagtat ttaacgcttt tctgcacaac ataatagtgt aaagtaaatg
     3961 attactttat aaataaatat cataaaggag gaactttata atggcacaaa aattagttcc
     4021 agaagcaaaa aatggtttat ctaaattcaa aaatgaagta gcaagcgaaa tgggagttcc
     4081 tttcactgac tacaatggta accttacttc taaacaatgc ggaagtgttg gtggagaaat
     4141 ggttaaaaga atggtagaac aatacgaaaa aggaatctaa aaattgaata aatattatta
     4201 attaggaaaa agagtcttta taatatctta tttaaaatta ataggatatt catatagact
     4261 ctttttaatt aaattttata atatttacaa attaattata atttattgtt aattttttaa
     4321 ctatcatacc tgtatcttaa ttatttttta cattttaata attaattggc taaatttctt
     4381 taatatatat cataactact ccacttcttc cctttgctta tcatgtaata ctatgatatt
     4441 ataatttatg tactatttcg ctatattttt tataataaat ttttttaatt tctatcttga
     4501 aaatttcaaa aattagtgat atagtttaaa tatgccattg ttaaataata attattatta
     4561 tttaattatt gtttaacata aatgacaata cttatatata tttataaaat gttagaaaag
     4621 aggcgctatg atgagagaag aatggaatga tttcaaaaca ggttcatgga caaaaagtat
     4681 tgacgtaaga aactttattc aaactaacta tactccatat gaaggtgatg atagtttctt
     4741 agctggagct actgaagata caaacaagct ttgggctgaa gttagtgaac tattcaaaaa
     4801 agaaagagaa aatggtggag ttttagatgt agatacagaa actatatctg gaatcaatga
     4861 atacaagcct ggttacattg atcaagcttt tgaaaaaatc gttggtgtac aaactgatgc
     4921 tccattaaag agagctgtaa tgccatacgg tggtataaga atggctgaaa atgcagctaa
     4981 agcttatgga tatgaagtaa gcccaagaat atctgaaata ttctctaaat acagaaaaac
     5041 tcacaaccaa ggtgttttcg atgcttatac ttcagaaatg agattagcta gaaaatctgg
     5101 tgttatcact ggtcttccag atgcttatgg tagaggaaga atcataggtg actacagaag
     5161 agttgcttta tacggtgttg atagattaat ccaagataaa gaacaacaaa aattaagctt
     5221 agaagttaaa acaattgatg aagatgtaat cagattaaga gaagaaatat ctgatcaaat
     5281 tcttgcatta aaagaattaa aaggattagc tgctagctac ggatttgata tatctcaacc
     5341 agctactaac gctaaagaag ctatacaatg gttatacttt ggattcttag gagctatcaa
     5401 agaccaaaat ggtgctgcga tgtctttagg aagaacttct acattcttag atatctatat
     5461 tgaaagagat ttaagaaacg gtgttatcac tgaagaagaa gctcaagaat taatggacca
     5521 cttcgtaatg aagttaagat tagttaaatt cttaagaact ccagaataca acgatttatt
     5581 ctcaggagat ccaacttggg ttactgaatc aatcggtggt atgggattag atggtagaac
     5641 tttagttact aagaactcat tcagagtact taacacatta tatactttag gaccatcacc
     5701 agaaccaaac ttaactgttt tatggtcaac tagattacct caaggattta aagatttctg
     5761 ttctaaggtt tctattgata catcatcagt tcaatacgaa aatgatgatt taatggctcc
     5821 atactgggga gatgactatg ctatcgcttg ttgtgtatct gcaatgagag ttggtaagca
     5881 aatgcaattc ttcggtgcta gagttaactt agctaaaact ttactttacg ctataaacgg
     5941 tggtaaagat gaaaagtacg gaatgcaagt tggacctaag actgctccat taactggtga
     6001 atacttagat tacaatgaag ttatggatag attcgatgtt atgactgact ggttagctaa
     6061 cctttacgtt aatacattaa atgttatcca ctacatgcat gacaaatatt catatgaaaa
     6121 attacaaatg gctttacatg acagagacgt attcagaact atggcttgtg gtatagctgg
     6181 tttatcagtt tgtgctgact ctatttctgc aatcaaatac gctaaagtta agccaataag
     6241 aaatgaagaa ggaatagctg tagatttcga agttgagggt gatttcccta aatacggaaa
     6301 cgacgatgac agagttgatg aaattgctgc atggttagtt gaaagcatga tgaataagat
     6361 cagacaaaac aagacttaca gaaatgctta ccacactcaa tcagtattaa caatcacttc
     6421 aaacgttgtt tacggtaaga aaactggtac aactccatgt ggaagaaaag ctggagaacc
     6481 atttgcacca ggagctaacc caatgcacgg aagagactgt agcggatcat tagcatcatt
     6541 aaactcagtt gctaaaatcc cttatgaaca ttcacaagat ggtgtttcta atacattctc
     6601 aatcgttcca gatgcattag gaaaaacacc tgaaaacaga atccataact taggtactat
     6661 gatggatgga tacttctctc aaggtgctca acacttaaac gtaaatgtat ttaatagaga
     6721 aactttatta gatgctatgg atcacccaga agaatatcca caattaacaa tcagagtttc
     6781 tggatatgct gttaacttca ttaaattaac aagagaacaa caattagacg ttataaacag
     6841 aacattccac aaatcaatgt aatttgttta taatattaaa tagagcttat tgcacacgca
     6901 ataagctctt attttttaaa ttaaatcaac aattactaaa tctggtctat taaatagtct
     6961 caatggaaat ccgctattac ccaatcctct actaactatt aatttatttt tttctccata
     7021 tactccttta taatacttag gaaataatcc ttgtcctggg gcaaatattc cacctattcc
     7081 tggtaatata aactgccctc catgtgcatg acctgaaaac ataatatcaa aattatattt
     7141 actataggct ccttcttcta catactcaaa attttcagga taatgtgata gtacaatttt
     7201 tattccatct aatctttcta atctgctaaa tattttttct atattttcag tgccatatct
     7261 gctattaact ttactataaa ataattcacc ttcatctatt cttttttctt ccaatcctaa
     7321 aatattaatc ttatttcctt ttacttctat agattctatt tcattttcta atacacatat
     7381 tttatttttt ttcaacttct ctactatttc acttactcta ctacatctca tttcattatt
     7441 tcctaatata taatacatag gaatgtcttt atttatactg ctacaaaatt caattatttc
     7501 atcaagcttt ttcatacttg aatctatcaa atcccctgtt gcaacaataa tatcaggttt
     7561 ttgttcaata atttttttat ataaaatata attatttttt ccaaactctt tactatgtaa
     7621 atctgatatt tgtgctattc taactttatt atttatcttc tgctttaatt ttatatttgt
     7681 tattacaatt ttattatttt gataataaca aaacactcct gtaagcatag ctatagcaat
     7741 tattatttcc ataaccctat cctcctttaa gttgttagtt ttttatcaag ctataaatag
     7801 taaattgctt atattatatg tattatataa ttaattttct ctcactgtac tttactttaa
     7861 aattaaaaaa tagaaattat atacttaaaa tataatttct attttatatt aaaatctaat
     7921 aatatacttt tttttataaa aaataaagct ctttagctat ttttacaata aattcataaa
     7981 cttcatcata tatagaatta aatcttttct gtaaaatatt tgataattcc aatgaatatt
     8041 ctatactatc tatttctata ccaataaaat agccatttac atttgttttc tcaagcctca
     8101 ccagacttaa gaggcttgtt tcatgtgcag ttatctcttt actaattagc ttatcacatt
     8161 cttctagctt tttaaaagta atttcaccag gatttattcc aaaataagtt gaatctaata
     8221 ttattataaa ttcatcatca tttatgtttt ctaagcaata taaataatca gtttctccaa
     8281 taaaaacttc tatttcatta atattatctt tatctactct cctttttata tttcttgcta
     8341 accttacacc tattccatca tcttttaaaa gaatatttcc tattccaaaa accttaacca
     8401 tagttactcc tatgaattaa ttattatatt tatgggttta tgcctattac ttgtcacatg
     8461 tacagcacaa tttaaacatg gatcaaaact tctaactatt cttcctattt ctactggagc
     8521 atttatatca ttaatctctg ctccaattaa agcttgttca acagttcctt ttaacccctt
     8581 tctatctgta ggtgaaaaat tccatgctga tggaggtatt aatgtataat ttgatatcat
     8641 tcaatttaaa tcaggagtaa tattcattgc attttcaaaa gctcttacag atgtaattgc
     8701 atgatgtgtt gaacatattc cacaaactct tggaactaat cttataatgt caaatggcgg
     8761 ccttccctca aacatttttt caaaacctct aaattggctt ccacttactt tagcatctac
     8821 aatcttatta ttttcaactt gtacttctat attaagtaat ccacttattc ttgttacagg
     8881 atctattctt atagtagtca tatttatccc cttattacac attactagag tcatacttta
     8941 caaaaggttc atagtcatct ggaaatcctg gtgatgcaca tcctatacat gttgtattat
     9001 cttcaatagg ccaattaaaa gtattattct acctacttac tgggcaatat gcataagtga
     9061 cggttcctct acatcccaat ttaaacatgc attctttttc accaaatttt tttgcaaaaa
     9121 ttccttgatc aaaaaatttt cttctagggc atatatcatg tattaaagta tcataataaa
     9181 ctaatggtct tccattacta tcaagttctg gaattccacc agaagctata tatcctaata
     9241 ttcctgctac ccaaactgga ttagccgggc atcctggaat ttttataata tctgttcttt
     9301 tcaaaaattc gcttacactt aaagcctttg ataaatttgg ctttgcagct gtaggccctc
     9361 caaaacatgc acaggttcct acagtaatta ttatacgtgc atttttagaa atatcactca
     9421 cagctttcat agcagttatc ttttcacctt tataagtagc tactgttgta taaagaccat
     9481 tgtcccttgt tggtatagct ccagatacta taaaaatata ttctgtatct aaattatcaa
     9541 ttatattttt ataagcttcc tcaccttgat ctccttgaat acttccaaaa tacttcatat
     9601 ccacaaattt ctccagcata tatataagat taggatcttc tgaatttaaa agtgaaataa
     9661 cttcaccaaa gcaccctgaa gtttctaacc atatagcatt aatctttttt actctgttat
     9721 tttcaacatt atctatggca ttatttatca tattcatagc taatttattt ttcttttgat
     9781 cttttgtatc tttatcaaaa attctatttt cccaaaaatc tatttcttct ataggtataa
     9841 tatatttatc acttttaaat ataaacataa aacctttcct tatttttatt atatttatgt
     9901 ttattttatt tcataataga ataatcaata aaaataaagt taaataaaat aaaaaactgt
     9961 gaaataaatc catatatcgg atttatctca cagttatata ttattcttgt tctgctaact
    10021 tctttaattc tgcatatttt tgtctagcat gttcttctgt catttggaat aattcttccg
    10081 cttgctcagg gaattgctta gcaattgcag agtatcttac ttgatccatt atgaagtctc
    10141 taaagcttcc ttgtggttct ttagaatcta agctaaatgg attctttcct tgttctttta
    10201 attctggatt gtatctgtat aaatgccagt atccagcctt aactgcttca tccatgtttc
    10261 ttatagagaa tcccattccc ttctttaatc catggctgat acaagttgag taagcaataa
    10321 tgattgatgg tccattatga gcttctgctt caagcattgc tttaactact tggttcttat
    10381 cagcaccaat agctacttgt gcaacataaa catttccata agacatcatc attcttccta
    10441 aatctttctt cttagtcttc ttacctgaag ctgctaattt agccatagct gcagcaggag
    10501 ttgatttaga agattgtcca ccagtgttag agtaaatttc tgtatcaaat actaatacat
    10561 ttacgtcttg tcctgatgct aatacatggt ctaatccacc gtatccgatg tcataagccc
    10621 aaccgtctcc tccaaggatc cattgtgatc tcttaacaag gaaatcagct ctttctttaa
    10681 tttcttcaac taatactttt gcttcttcat tttcaatgtt gttttcagct aaaatagctt
    10741 caacttctct tgaatgaact tttgaaagct ctccgttatc tttattttct aaccagtttt
    10801 tgaatacttc tttatattct tcagctatat ccatagaaat taagctttcc atatttgaag
    10861 ctattttctt tctcatttga tcagctgcta agaacatacc gtatccaaac tcagcattat
    10921 cttcaaataa tgagttagcc caagctggtc ccttaccttc atggttcttt gtatatggtg
    10981 ttgaaggtgc tgaacctccc catattgatg aacatccagt tgcattagca atcatcattc
    11041 tatcaccgaa taattgagtt actaacttaa tatatggagt ttctccacaa ccagcacatg
    11101 ctcctgagaa ctcgataagt ggttgtttga attggctatc cttaactgtt ttacctggag
    11161 ttaagtgttc tttgtttgat acttcttttg atactgagaa atcccagttt gctacttctg
    11221 tttctacttg tgttccaagt ggcttcattt ctaatgcctt acctggtgct ggacaaatat
    11281 caacacagtt attacatcca gtacaatcta atgtacttac ttgaattctg tagtttaatc
    11341 ctgctaatgt tttaccagta gctttcttag tttcaaatcc tgctggtgct tttgctaatt
    11401 cttcatcagt tactagaact ggtctaatac atgcatgtgg acaaacgaaa gcacattggt
    11461 tacattgaat acattttgac atattccatt ctggaacatc tgtagcaaca cctctttttt
    11521 catatgctgc agttcctgct gggaatgtac catcttctaa tccattgaat gcacttactg
    11581 gtagtttatc tccttctaaa gcattcatcg gattcattat gtttttgacg aaatctgtta
    11641 cttctttagt ttctactttt gcttcttcag tagcagtctt ccagctttca ggtacattaa
    11701 tcttaactaa tgaattcata ccagcttcaa cagcttcgta gttcatgtta acaaccttat
    11761 cacccttctt accgtaagcc ttcttaattg aagcttttaa gtattctgta gcttcttctt
    11821 gtgggataat ttctgctaat ttaaagaatg cagattgcat tatcatatta attcttctac
    11881 ctaatcctat ttcagaagca atcttagttg cattaactgt atagaagttt atttcatttt
    11941 cagctatgta tctcttcatc ttagctggta attttctttc aatttcttct tcgttccaaa
    12001 ttgtatttaa tacgaagttt ccaccttttt taagaccttt taataaatca tattgattta
    12061 cgtaagcttg cacgtgacat gctatgtaat cagcttcatc aataaggtaa gttgatctta
    12121 ttggtgtatc tccaaatctt aagtgagaca tagttacccc accagatttc tttgagtcat
    12181 atgcaaagta agcttgtacg tatttatctg tattttcacc aataatctta atagcttgct
    12241 tattagctcc tactgtacca tctgatccta atccccagaa cttacatcta actgttcctg
    12301 gtgttgcaat tcttaattca tcttctactg gaattgaagt gaaagtaaca tcatcttcta
    12361 tacctacagt aaagaagttc ttagaatttt ctttctttaa gttatcaaat acagctttga
    12421 tatcagatgg tgtaacatcc ttagaagcta atccataacg tccaccaact atcttaggtg
    12481 cattttcttt tccatagaat gcagaacata catctaagta taatggttca ccattacatc
    12541 ctggttcttt tgttctatca attacacaaa tcttttctac tgattgtggt ataaccttta
    12601 ataaatgctc tacagagaat ggtctgaata aatgaacttt aactaatcca tatttttctc
    12661 ctctagcatt taattcatct atagtttctt ctatagcttc agttactgaa cccatagcaa
    12721 caattatttc tttagcatct tctgctccat agtaattgaa taatccatag cttcttcctg
    12781 tcttctcttc cattttagcc atgtattctt caactattgg aattatgtca ttatagaatt
    12841 tattagaagc ttctcttgtt tggaaataaa tatctgagtt ttgagctgtt cctcttgtaa
    12901 cagggttatt tggagttaac gctctacttc taaattcttt taaagcttct ctatctaaca
    12961 tttctgcata atcttcataa tctaatactt caactttttg aatttcatga gatgttctaa
    13021 atccatcaaa gaagtttaca aaaggtaatc ttcctttaat agctgaaagg tgagatactg
    13081 gagctaagtc agcaacttct tgtactgatc cagctgcaag cataacacat cctgtcattc
    13141 ttgctgccat aacatcttga tgatctccaa atattgataa tgcttgagat gctattgctc
    13201 tagcacttac atggaataca cctggtaata attctcctgc taccttgtac atgtttggta
    13261 acataagtaa tagaccttgt gatgcagtaa aagtagttgt taatgcacca gcttgaagtg
    13321 aaccgtggaa tgtaccagca gctcctgctt ctgattgcat ttctacaaca ttaactgttt
    13381 gtccaaaaat atttttcttc ccttgagcag cccattcatc aacaacttct gccattgtag
    13441 tagatggagt tatagggaat attgcagcta catctgtaaa cgcatatgct acgtgagcag
    13501 cagccgtatt accatcaata gtcatcattc tctttgccat gataatatac cttctttcat
    13561 catcctaaat gtttcttaaa taattataat tgttatttaa taataattat tatacttcat
    13621 ttttattttt tttctagtac ttttcttaga aatattcctt agtataattt tgtaatcttt
    13681 tgtcacttat tagtataata acatactttc atttcttcaa tagaaaacta ccatctttat
    13741 acatttaatt tttaaatagt aattaaaaaa tttttaaatg gttatatatc taagtaatta
    13801 cacttaaact aattaattag atattttgac catacataat attactcttt atgttatttt
    13861 tctacaagaa ggcacttttt ttatatatag tgtcaaaaaa gatactaagt atatagtttt
    13921 atacttggtt ttatgttatt atttatattt gtacgaataa aggaggtgtt atcatgaata
    13981 aaatacttac ttttcataat gattgccgtc ttaatgatcg ttgtgccaaa tatgaaacat
    14041 gtccaatgat acttgttcat aaaatattat ctggtaaatg gaaaatttta attttatggt
    14101 atttaagtaa tgatactcta agatttagcg aattaaaacg aaagttgcca ggtacaacgc
    14161 agaaaatgct aaccaatcaa ttaagaagtt tagaagaaga taatcttata tttagaaaag
    14221 tttatcctgt tgttccacct aaagtagaat atggacttac tgatatcggc aaaaaaataa
    14281 ttcctcttct tgaatctatg tattcatatg gagttgaata ctctaataca aaaaattaaa
    14341 agaaattagc taacagcaaa ttgtaattga gttagctagt ttcttttaat ttataatata
    14401 ttaatatttt attgcaaata ctaaaataaa tctgttaaac cgattcactt gctttgttta
    14461 tttattgaca atagttattg atagattata attattatta tagaccatag aggtatttaa
    14521 taataaataa aaaaaaggag atttttacat gtctaataca ttcaaaataa ctgaagacct
    14581 attttgggta ggagcccttg acccaaacct aagaattttt gacataataa tggaaactaa
    14641 atttggaaca tcttacaact cttatctttt aaagggttct gatggaattg cattgtttga
    14701 aactgtaaaa gaaaaattct ttgatgaaca tttagataaa attcgctcta ttgtgaattt
    14761 agaggatata aattacgttg ttgttaatca tacagaacct gatcatgctg gatcagttga
    14821 aaaaatactt gagtatgctc ctaatgctac tgtagttgga agcactttag ctattaaata
    14881 tttaagtgaa attattaata aacctttcaa aagtaaagta gttaaagatt gggaaacatt
    14941 atctttaggt aataaaactt taaaatttat tagtgcccct caattacatt ggcctgatac
    15001 aatgtacaca tacgtaatag aagatgaaac attaattact tgtgattctt ttggtgctca
    15061 ttattgcgat gaacgtgttt taaaaagtgc aattgaagat agcaaagaag atgactatat
    15121 agaagcttat aattattact ttagaatgat tatgggacca ttcaaacctt ttatgcttaa
    15181 agcacttgat aaaattaagg atttaaactt aaagtacatt tgtcctggac atggattagt
    15241 attagatcat actaatattg aaaagtttgt taatctttat agagaatggt gtcaaccaac
    15301 aaaaagagaa aaacaaagca tagtaatacc atatgttact gcatacggat atactgaaga
    15361 aattgctaaa gaaataaaaa gaggtattga agcttcaaac tttgatgttg atattttaat
    15421 gtataactta gttacagcag acatgaatga agtattaaat gaaattaatc aatgtagtgg
    15481 tttattacta ggttctccta cattattatc tgatacttta ccacaaatat ggactatttt
    15541 atcttcatta aatccagtaa ttcataaagg attaccagca agttgctttg gatcatatgg
    15601 ttggagtgga gaagctctta aaaatattaa cgaaagatat aaacaactta aatttaatgt
    15661 agtatgtgaa ccactaggta tagtatttag acctagtgaa gaaaacttaa aatctgctta
    15721 tgattttgga ttagaatttg caaataaagt tttaaaataa aaaaacaa
//
