LOCUS       NZ_LR134338.1          23324 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR134338.1 Brevibacillus brevis strain NCTC2611 chromosome 1,
            complete sequence.
ACCESSION   NZ_LR134338
VERSION     NZ_LR134338.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:02:35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4488786
            Orig. end    :: 4512110
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23324
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[4498786:4502110]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13324
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23324
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23324
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="5"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(208..825)
                     /locus_tag="ctg1_4282"
                     /transl_table=11
                     /translation="MEVDLLMSIIEQYGYVAIFFLLWLGIVGLPIPDELVVATGGFLAS
                     IGVLNPWYSFLAGYLGVASGLTIGFLLGKYFGKPILQWLCKTEKTRNAVNRSTGLLEKY
                     GTAALCISYLFPVVRHVVPYLVGLGGMTFRRYAMLSYPIGLVWTIGFYFLGYVFGNNVE
                     AIIEVIRKYGFYALLVIVVVLAVVFFVRKQFMANRAYRAKGE"
     CDS             complement(996..1664)
                     /locus_tag="ctg1_4283"
                     /transl_table=11
                     /translation="MNASEYTGAVEGLLRTHGDSIVAGPMAQYMKNHFPFLGIKSPQRK
                     ELTKQIFRDYGAPENWEQVVRSLWALPAREYQYVALDVLEKSKKRLTPDHLPFVVELIT
                     TKSWWDTVDYLASHATGKLFALHPELIEPNTTAWMDGANMWLQRTAILFQLSYKDKTDQ
                     RLLFSLVERCADSKEFFIQKAIGWALREYAKTNPNAVREFVEATPIASLSRREALKHLS
                     "
     CDS             complement(1703..3481)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4284"
                     /sec_met_domain="Radical_SAM (E-value: 7.7e-16, bitscore:
                     57.5, seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="B12-binding (E-value: 3.4e-21, bitscore:
                     74.1, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILLSTLNAKFIHSSLALRYLRSYAQEAFPSIELVEYTINDVTL
                     NIVADIHKRKPDVVAFSCYIWNIRETLSVIRTLKKICPDVPIILGGPEVTYDADEWMKK
                     HPEIDVICIGEGEQTFLELLQVYQESLQTKQTPRLRDVAGIAYREEEYVRFSMPRAQVE
                     EMDSIPSPYADHLDELNNRVVYFEASRGCPFKCQYCLSSIEDGVRYFSLERVKEDLMRL
                     INHGVKTIKFVDRTFNINKKYALEIFQFLIDNHNGTIFQFEITADILRADVLDFLTENA
                     PPGIFRFEIGVQSTNDETNRLVQRIQRFDRLARTVTQIKDSKKIDQHLDLIAGLPEEDY
                     ASFRKTFNDVFGLRPEELQLGFLKMLRGTGVRARAANHGYVFMDEAPYEILGNNVLSFD
                     DMQKIKRVEDILEKYWNAHRMDYTVEWLLANQFETAFDFFQAFGDYWENQGWSRIGHQL
                     EDLFVRLQKFLHFQQVDGMGHVLSMMKFDFLRNQKHRPRKLWWEDVMDKEEMQQTFAVL
                     TEQRERLRDDFAAHAALEKDYFKHTLTAKVTFDIEKWLETGEIVEGDFILVVYYPYKDE
                     EQNAFAVVKQDVQAAG"
     CDS             complement(3604..4110)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4285"
                     /sec_met_domain="MoCF_biosynth (E-value: 2.9e-32, bitscore:
                     109.9, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQEHKALSPKQVTCMVITVSDTRTEDTDKSGQLMKELLTEAGH
                     SVVLYQIVKDEPVQVIAAIEAGIAHDDVQVILLNGGTGISPRDNTFEAVSGLLDKEMPG
                     FGELFRMLSFTEDIGSAAMLSRAIAGTRKGKMIFSTPGSTGAVRLAMNRLIVPELGHVV
                     RELNR"
     CDS             4285..5727
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4286"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-15, bitscore:
                     55.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPERPYFSFHFHKQSHTPIYVQLAEQLKTAILRGAFLVDGQQLIS
                     LRDMKTISGCSLETVKKAYDHLALEGWLEAVHGKGYYLTQLAKEARLENRLPLTDIPIA
                     SLADSSPRPSEELVKRLRGAFYESLTVLDEPSAKKKIMRTQAAKVFADHLSRRGLPHSP
                     ERLLLFNRSTSGFAFLAQRVMNARDVVYVEEYSYPVFLRLLSQCGITVRPIRMDEEGVC
                     IQALNEEQEHYPANWLLINPHYQFPTGISYSLKRKEELLEWAQNHNVRLIENDHYGDLW
                     FEEPSVPLYQMAAQAKSTIEVYYLHSLSKTLARDLQLGVLMLPSELSNDELERYSQLVS
                     MTGAEPSLLVVEAAVQLLDDPWFYEEFLADRRALFQARFLRLWQERRHALPDHARMFPI
                     TGGLNTWIKWGTPTARATEQEERVVAILREEGLELTGGHAFRVADEPADILRCPAVRFP
                     LAPLEERELKHWLHRLGAALLR"
     CDS             5814..7160
                     /locus_tag="ctg1_4287"
                     /transl_table=11
                     /translation="MIKKIVEKLHLDPPKTLVLGFALIIFLGALLLTLPVATVDGLGLH
                     WLDALFTATSATCVTGLVVVDTGTTFTTFGQLVILSLIQIGGLGFMTFATFFALIMRKK
                     ISLRERLILQESLNQMSIEGIVRLAKMILIFTALTEFIGGVLLSIRFAFDFPLQKAIYF
                     GFFHAISNFNNAGFDLMGEFASLTAYVEDPLVNLVVCLMIILGGIGFIVVSELYDYRHN
                     RRLSLHTKVVLTTTGLLITAGTVLIFILEYNNPKTLQPLSMMGKVLGSFYQSVTPRTAG
                     SNTLNIGDMYQSSLFLIIILMFIGASPGSTGGGIKTTTFATLIGAVIAQVKGKEDVIFF
                     RQRILSHMVYKSLTLTMIALFIVLVMTMVLSITETGARFEMVLFEVTSAFATTGLSMGL
                     TPNLTPLGKALIILTMFAGRLGPLTIAFALAQRKQKEYFRYPKGKITIG"
     CDS             complement(7232..8326)
                     /locus_tag="ctg1_4288"
                     /transl_table=11
                     /translation="MKKNYRIAVLPGDGIGPEIMQEAVKVLTLVGELEGVTFTCEEGRI
                     GGIAIDTDGTPLPEETVTLAKQADAVLLGAVGGPKWDQNPGHLRPETGLLGIRKALGLF
                     ANIRPATMHSSLVDASSLKPEVVSGVDLIVVRELTGGIYFGEKKRYDGPNGEVAEDQCI
                     YHEAEVERIIRVGFDIARKRQKRLVSVDKANVLESSRLWRKVAERVAADYPDVELSHQL
                     VDSCAMQLVREPKQFDVIVTENMFGDILSDQAAMLTGSIGMLSSASLAAGSFGLYEPVH
                     GSAPDIAGKGIANPLATILSVAMMLRLSLGMDEAAAAVENAVWSVLEAGHRTGDIAADR
                     SKAIGTVEMGQLVRDELSKQWQKQ"
     CDS             complement(8406..9944)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4289"
                     /sec_met_domain="HMGL-like (E-value: 7.6e-100, bitscore:
                     332.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTIEIFDTTLRDGEQSPGVNISTNEKVEIALQLEKLGVNKIEAG
                     FAAASPGDQKSVAEVAKRVKNATVVSLARAVKDDMDKAYEALRNAQNASLHVFLATSPI
                     HRQFKLNMSKEEVLARAVEAVTYAKKYFTEVQFSAEDAARTEIDFLAEVVEAVIKAGAT
                     TVNIPDTVGYMTPYQYGNIFRELKKRVPSTDLIRLSCHCHDDLGMAVANSLAAVEGGAT
                     QVEGTINGIGERAGNAALEEVALALETRKDYYQTTTKLNLKEIARTSQLVSRLTGMIVP
                     GNKAVVGANAFAHESGIHQDGVLKEVTTYEIIRPESVGFKSNKLVLGKHSGRHAFKEKL
                     VDLGYHLEQEEVNAAFAAFKVLCDKKKEITDDDILALVDSKMVRGPEAFQLESVQLAYG
                     NISVPTASVRLVRADGSVCEEAACGNGSVDSIYKAIDRATGEEVSLVDYKILSVTHGQD
                     ALGEVFVRLQQGDLIVTGRGVSTDVLEASAIAYVRAVNKIMERRGEPAPVSATI"
     CDS             complement(10001..11023)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4290"
                     /sec_met_domain="IlvN (E-value: 4.1e-77, bitscore: 256.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.5e-66, bitscore: 220.5,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKMYYEADVKQEVLRGKTIAIIGYGSQGHAQAQNLRDSGYKVVV
                     GLRPGKSWDVAAKDGFEVLTVAEATKRADVVQILMPDERQAQVYRDEIAPNLKSGAALC
                     FSHGFNIHYAQIVPPADVDVIMAAPKSPGHLVRRVYQEGFGVPGLIAIYQDATGNAKDL
                     ALAYSSGIGCTKAGVIETSFREETETDLFGEQAVLCGGASELVKAGFDTLVEAGYAPEI
                     AYFECLHELKLIVDLMYEGGLARMRYSISDTAEYGDYSTGRRIITDETRKEMKKVLAEI
                     QDGTFARNWILENQANRPGFTSRRRLESEHGIEVVGEQLRGMMSWINKDTKKEEAKIGQ
                     "
     CDS             complement(11080..11586)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4291"
                     /sec_met_domain="ALS_ss_C (E-value: 2.4e-27, bitscore:
                     93.5, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQHTISVLVNDQPGVLTRVATLFGQRGFNIDSITVGGTEEQGLS
                     RMIISTGGDDRQINQLMKQLHKLIDVISVTNLSENPFVSRELALIKVTASPSQLAELNG
                     IVEPFRAAIVDVGPSSLIVQVTGDTEKIDALLVLLQSYGVIELTRTGSVAMARSIVPAT
                     AAATV"
     CDS             complement(11588..13324)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4292"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-54, bitscore:
                     183.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVEMAELQKKNGIPPIQFGEEVTGAETLLRCLILEQVEYIFGYP
                     GGAVLPIYDSLYGSYFKHILTRHEQGAIHAADGYARATGKPGVCIATSGPGATNLVTGI
                     ATAQMDSVPLVCITGNVAQSLIGTDAFQEANITGITIPITKHSYFVRDIRDLPRIVKEA
                     FHIATTGRPGPVLIDIPKDVANAKAPFTYPDKVEIRGYRASLVPSDEEVQEFVKAVGEA
                     KRPVILAGGGIIAAQAEKELRDFAEKTRIPVINTFMGLGGFPGTHELSLAMPGMHGNYT
                     ANQALLNADCVIGLGARFDDRITMGRTKEFAPKARIVHVDIDPAELGKNVDTAVTVAGD
                     VKSTLAKAIPLAKTCDSEAWISQLKEWQKQYPYKYKKDGDVLKPQAVIELLYNSTDGEA
                     IVTTDVGQHQMWTAQYYKFKHPRSFISSGGLGTMGFGFPAAIGAQIAHPDRTVISVVGD
                     GGFQMTNQELAIVSQYNIPVKVAIVNNQCLGMVRQWQELFYDNRYSQIDLTCSPDFVKL
                     AEAYGVKGLRASTPEEAEAVWAEALAHDGPVVVDFRVAQEENVYPMVASGDTLDQMELG
                     DD"
     CDS             13587..14054
                     /locus_tag="ctg1_4293"
                     /transl_table=11
                     /translation="MRRTLYPFLSIRALCKRGNAHHPRHGLLFKQYFQYCCCQNKVLRL
                     IIARHLGGVNENKKILLDFRPNECSVRNGYTARFLLESGYNKTVKTVLLTASGRYTFMK
                     NVETFFTENWKACPVFATEKERHCRPSPPFRFRFIAGISILLSKSLRLPDE"
     CDS             complement(13999..15099)
                     /locus_tag="ctg1_4294"
                     /transl_table=11
                     /translation="VKQTILPHGIKKAIIVDKWTLSDIECLAIGAFSPLAGFMEEADYH
                     TVVETMRLANGTVWPLPVTLAVDADEHDDLVPGDSILLRGEDGVDYAILRVNSCYVPDK
                     MREAELVFRTVDLAHPGVKKLFEKPNLYVGGPVEVLQKPRPERFSDFYLTPAETRERFR
                     KNGWKTVVGFQTRNPVHRAHEYIQKAALEIVDGLFLNPLMGETKSDDVPAQVRMKSYLA
                     LLENYYPHNRVLLGAFPAAMRYAGPREAVFHALVRKNYGCTHFIVGRDHAGVGDYYGTY
                     DAQHIFSEFAPGELGIQLLFFEHSFYCTACQGMATTKTCPHDKDSHLTLSGTKVREMLR
                     NGITPPPEFTRPEVATILIEGLKSPQ"
     CDS             complement(15120..15821)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4295"
                     /sec_met_domain="PAPS_reduct (E-value: 1.7e-50, bitscore:
                     170.0, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRQKMADEEIQEWASRLEAHAPQDVLVNAVENYAASLILAASF
                     GAEDVVLIDMQHKLAPTIPVFYLDTNIHFAETYDTRDKLQARYSTTFIQVQPQLTLTEQ
                     AEKHGEKLWEREPNLCCEIRKVEPLKRVLSNYQAWITGIRREQSPTRANTKKVEWDEKF
                     NLVKFNPLADWTEAQVWEYIHAHDVPYNPLHDRNYPSIGCRVCTRAVMPGQDSRSGRWA
                     GFEKTECGLHK"
     CDS             complement(16060..16299)
                     /locus_tag="ctg1_4296"
                     /transl_table=11
                     /translation="MRKKWMIMGVTAVVCSALFVPGAFAKDKDDSYSVPPSFVSPGSYA
                     IPTVQTVKVTDTKKTQQIGPSFIFAPAVNEKDEK"
     CDS             complement(16462..16698)
                     /locus_tag="ctg1_4297"
                     /transl_table=11
                     /translation="MRKQKWMMMGITAVVCSAMFVPGAFAKDKDDSYSVTPSIFAPGPH
                     SAPVVQKTDAVAGTQTAGSAFTFTPIVNEKEEN"
     CDS             16949..18001
                     /locus_tag="ctg1_4298"
                     /transl_table=11
                     /translation="MSKLRGVLLSGLLLIPILSGCSQEAKPVEAESGQTQNQPSTQTTT
                     APEPTAETKAKEEAKPEGEAVNFEVVGQPSSDAPADQGDPKATLGGELTINSKTLTIKG
                     SSNLLPGAKVKANVTAKGYNMWGYNDETEVNSDGSFELEVKKPDVKAQMEVELSFTSDQ
                     QSDRIQEAYGKTGEKLTGDYVYQYLDSDKLKYKVATFAYVDPKAQTNTKVPFETPVWDK
                     PSDYGQPAIWIKPSITKNGKSLTVAAKSNFLEGTKISGGLDIPNHVHYGYTDQTEVKPD
                     GSFSLQIPQPDKVKQYYVLIQFIPDDNMWPTVKDAYGEKGEKLKGEFIKIKDSDKKTVN
                     MIEMKIKVDL"
     CDS             complement(18067..18954)
                     /locus_tag="ctg1_4299"
                     /transl_table=11
                     /translation="MRNGFVSTSQKGLNQELLPYQLYQKAKRYGIWNPQDIDFTQDRED
                     YAKMNPEQKEETLGRIAGFLGGEEAVTLDLLPLIMVIAEEGRLEEEMYLTTFLFEEAKH
                     TEFFRLVLDNIGESGDLHHFHDDVYKRIFHEILPNALNRLLTDKSPEAIAEASTVYNMF
                     VEGVLAETGYYAFYEALSKTGLMPGLMQGIGYLKTDESRHISYGTFLLQRLICEHPHIY
                     DVIAKKMDELAPMASHLYDWMDDPQGVSAFGVKVADLQQFAKKQLSVRMEVLARAKGQT
                     IEELYKHTRTTIDV"
     CDS             19174..19860
                     /locus_tag="ctg1_4300"
                     /transl_table=11
                     /translation="MVSPELNMYIDRIEETTFYEEKLVLAVRGFVDLFPFMGAILCNYS
                     TLSQMGEGLWSILDQELCSIRDIRVDMRNMPLIQHAIREQRAVLLDSEAIRQFPPDLVY
                     GAPYALILPISYGPNVLGYAGISWHQDGCSGINHQLVQSLSAYCSMLGKVLATDSLRPK
                     TVKLSRREVEVMQRMSWGESVKEMADWMGISEFTVQDYIKSALKKLGVQNRAQGVADAI
                     RQRIIC"
     CDS             complement(20061..20420)
                     /locus_tag="ctg1_4301"
                     /transl_table=11
                     /translation="MPRVKGGIVTRRRHKKILKLAKGYFGSKHRLFKSANAQVMKSLLY
                     AYRDRRQKKRDFRKLWITRINAQARMNGLSYSRLMHGLKVAGIEVNRKMLADLAVNDKA
                     AFNELATVAKGKLNA"
     CDS             complement(20512..20709)
                     /locus_tag="ctg1_4302"
                     /transl_table=11
                     /translation="MPKMKTNKAAAKRFKKTGSGQLKRDRAFGSHLFANKSTKAKRHLR
                     KAALVSKGDQKRIEQMLTYL"
     CDS             complement(20740..21321)
                     /locus_tag="ctg1_4303"
                     /transl_table=11
                     /translation="VRAQIAFAHFCSFSKLTGVASISKDQMLINEAIRAREVRLIGADG
                     SQLGVVPFREALRIAQEAELDLVNVAPTAKPPVCRIMDYGKFKYEQAKKEKEARKNQKI
                     IELKEVRFSSNIEEHDFQTKLRNVRKFLEDQHKVKCTIRFRGREITHSEIGLGVMERVA
                     AQCEDLATPERKPKIEGRSMIMILAPKAEK"
     CDS             complement(21507..22526)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4304"
                     /sec_met_domain="Radical_SAM (E-value: 9.6e-33, bitscore:
                     112.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEKVLDLRNRPLRDLRISVTDKCNFRCRYCMPAEIFGPDFEFLP
                     QSKLLTFEEITRLTQIFTSLGVGKIRITGGEPLMRRNLPELIRMIRGVEGVQDIAMTTN
                     GSLLTRHAQALKEAGLDRVTVSLDSLDNERFGMLNGRGYQVDAVLEGIRVAADAGLSIK
                     INMVVQRGVNDQDILPMARYFREQGHTLRFIEFMDVGNSNGWRLDQVVPSREIVRMIHE
                     EMPLVATEANYYGEVASRYRYEGSNQEIGLISSVTQAFCSTCTRARLSAEGKLYNCLFA
                     SSGDDLREPVRDGRTDEEIRELIRAIWERRDVRYSEERLSETPGLAKREKVEMSHIGG"
ORIGIN
        1 cagttccgga acccgaaaac ctttttcttt cgccagacgc ttgtctgtct gcatcaggta
       61 ataagcatag ccattcagca gcaaagctcc tgccgccagc acccagatat tcgaattgaa
      121 gtatcctgcc aagaggagga cccagcttat gacgagcacc agcacgaaat tgcggcggtg
      181 ggcagctaat tgttgatggt acatttctta ttctcctttt gcccgatatg cccgatttgc
      241 cataaactgc ttgcgtacga agaataccac agccaataca accacgatca ccagcaaagc
      301 gtagaaaccg tatttgcgga tgacttcgat aatggcttcc acattattac cgaatacata
      361 gccgagaaaa taaaagccga tggtccaaac caatccgatc ggataagaca gcatcgcata
      421 acgacgaaac gtcataccgc caagcccgac caaataaggt acgacatgac ggacaaccgg
      481 aaataagtag ctgatgcaaa gagcagcagt accatacttc tccagcaagc ccgttgatcg
      541 attcacggca ttcctcgttt tctcggtttt gcacagccat tgcaatatcg gtttcccaaa
      601 gtactttcca agtaaaaagc caatcgtcaa tccggaggca acccctaaat accccgctaa
      661 aaaagaatac caagggttta aaacgccgat ggaggcaaga aatcctcctg tagcgacaac
      721 cagctcatcg ggaatcggca aaccgacaat ccctagccaa agcaggaaaa aaatcgctac
      781 gtagccgtat tgctctatga ttgacatcag caggtcgact tccatgaggc aaaatcccct
      841 atcttgccac agtgcggtca tttcttgaca tactagcagc tatggcatcg cacgatatct
      901 gactctatgt attacgtatg aatctcaaaa aaggtacttg tttattttgc aatagatgca
      961 cgtattttat caaccacaga tacaccagga ctctatcatg atagatgttt gagcgcttca
     1021 cgtctggaca ggctcgcgat tggagtcgct tctacaaatt cacgcacggc gttgggattt
     1081 gttttcgcat actctctcaa cgcccagccg attgccttct gaataaaaaa ctctttggaa
     1141 tccgcgcatc tttccaccaa ggaaaaaagc agccgctgat ctgtcttgtc cttgtacgac
     1201 aactgaaata aaatcgccgt tcgttgcagc cacatgtttg ctccatccat ccaggctgtc
     1261 gtattcggct cgatcagttc gggatgcaag gcaaacaatt tgcctgttgc atgggaagcc
     1321 aaataatcca cggtatccca ccacgatttt gtcgtgataa gttcaacaac gaacgggaga
     1381 tggtcagggg tgagacgctt tttggacttc tcgagtacgt caagcgctac atactggtac
     1441 tctcgcgctg gcaaagccca caaggaacga acgacctgct cccaattttc gggagcgcca
     1501 taatcacgaa agatttgttt ggtcagttct ttgcgctgcg gcgattttat tcccagaaaa
     1561 ggaaaatgat ttttcatgta ctgcgccatg gggccagcca caattgaatc gccatgtgta
     1621 cgcaacagtc cctcgacagc ccccgtatac tcgcttgcgt tcatctgcgt ctactccccc
     1681 aactcctctg atatctggtg gtttagcctg ctgcttggac gtcctgcttg acgacagcaa
     1741 aagcattttg ctcttcatct ttgtacggat aatacacgac gagtataaag tcaccctcga
     1801 caatctcacc agtctccaac catttttcta tgtcaaaggt caccttggca gtcagcgtgt
     1861 gcttgaagta atctttttcc aatgcagcat gtgccgcaaa atcatcgcgg agtcgctcac
     1921 gctgctcggt taggacagcg aacgtctgct gcatctcttc cttgtccatg acatcctccc
     1981 accacagctt gcgcgggcga tgcttctggt tgcgcaggaa atcgaatttc atcatgctga
     2041 gcacatgccc cataccgtct acttgctgga aatgcaaaaa cttctgcaag cgcacgaaca
     2101 aatcctctaa ttgatggccg attcggctcc agccttgatt ttcccaatag tcgccaaatg
     2161 cctggaagaa gtcaaaagcc gtttcgaatt gattcgccaa cagccactcc actgtatagt
     2221 ccatccggtg cgcattccag tacttttcca gaatgtcttc tacacgcttg attttttgca
     2281 tgtcatcaaa ggaaaggacg ttgttcccca aaatttcgta aggtgcctca tccataaaaa
     2341 catagccgtg attagccgca cgcgcacgaa cacctgtccc gcgcagcatt ttcaaaaagc
     2401 cgagctgaag ctcttccggg cgtagaccaa acacgtcatt gaaggttttg cggaaggatg
     2461 catagtcttc ctcaggcaaa ccagcgatca agtccagatg ctgatcgatt tttttcgaat
     2521 ccttgatctg tgtcactgta cgcgcaaggc gatcgaagcg ctgaatccgc tgaacaaggc
     2581 ggttggtctc atcattcgtg gactgaaccc caatctcgaa gcggaaaatg cctggcggtg
     2641 cgttctcggt caagaagtcg agtacgtctg cacgcaaaat gtctgccgtg atctcgaatt
     2701 gaaagattgt cccattgtgg ttgtcgatca aaaactgaaa gatttccaac gcatattttt
     2761 tattgatgtt aaatgtgcga tccacgaact tgatcgtttt gacgccgtga ttgatcaaac
     2821 gcatgagatc ttctttcact cgttccagac tgaaatagcg tacgccgtct tcaatcgacg
     2881 acagacagta ttggcatttg aacggacagc cacgggaagc ctcaaaatag acgacgcggt
     2941 tgttcagctc gtccagatgg tccgcgtatg gcgaaggaat gctgtccatc tcttccactt
     3001 gcgcacgcgg catggaaaaa cgaacgtact cctcttcgcg ataagcgatt ccggctacat
     3061 cacgcaggcg tggagtctgc ttggtttgca atgattcctg atacacctgc aaaagctcca
     3121 aaaaggtctg ctccccttca ccaatgcaga tgacatcgat ttcaggatgc ttcttcatcc
     3181 attcgtccgc atcataggtt acctctggtc ccccgaggat aattggaaca tccgggcaaa
     3241 tctttttcaa cgtgcgaatg acactaagcg tctcgcgaat gttccagata taacaggaaa
     3301 atgcaacgac atcgggcttt cgcttgtgta tatctgctac tatatttaac gtcacatcgt
     3361 tgatggtata ctccaccagc tcaatcgaag gaaatgcttc ctgggcatag ctccgcaaat
     3421 agcgcaaagc gagagaggag tgaataaact tggcgtttaa ggtcgatagt aaaatcttca
     3481 tggatgggtc tactctcctt gcaaaattcg gcaccaaaaa accatctgca atcgatggtt
     3541 catggtctga ccgatctttt tcctttcgta acagtaccat acgagactag taacggcaaa
     3601 tcgttaccgg tttaattcgc gcaccacatg ccccagctcc ggcacgatca accgattcat
     3661 cgccagtcgc accgcacctg tcgagcctgg cgtggaaaaa atcattttcc ctttccgcgt
     3721 ccctgcaatc gcacgactga gcatcgctgc cgagccgatg tcttctgtga agctcaacat
     3781 ccgaaacagc tcgccaaatc ccggcatttc cttatcaagc aagccagaaa cagcctcaaa
     3841 ggtattgtct cgaggcgaaa tgccggtacc gccattgaga agaatgactt gaacgtcgtc
     3901 atgtgcgatt cctgcttcga ttgccgcaat gacctgtaca ggctcgtcct taacaatttg
     3961 ataaagtaca acgctgtgac cagcttcagt cagaagctct ttcattaact gtccgctttt
     4021 atctgtatcc tctgtccgag tatcggaaac ggtaatgacc atgcatgtga cttgcttggg
     4081 cgatagcgcc ttgtgttcct gcgtactcat ccgtaatttc ctcatttctt caatatatat
     4141 cttttctcat gataccatgt tcgcgattcc aataccctcg tcgttccggc aacaatttct
     4201 tcactcccta tacccgagat gcttcgcttt cctatataat gctgatgact gctatttttt
     4261 cgacagacaa ggaggcgtgc gcgaatgcca gagcgacctt atttttcttt tcatttccac
     4321 aaacaatcgc acacaccgat ctatgtacaa ctcgctgaac aattaaaaac agcgattctg
     4381 cgtggtgcct ttcttgtaga tggacaacaa ttgatatcgc tgcgagatat gaaaacaatt
     4441 agcggctgct cgttggagac agtcaaaaaa gcatacgatc atcttgcttt ggaaggctgg
     4501 ctggaagctg tgcatggtaa aggctattac ttgacgcagc ttgccaaaga agctcgtttg
     4561 gaaaatcgcc tcccgctcac agatattccg attgcttccc tagctgattc ctcccctcgt
     4621 ccaagcgaag agctggtgaa gcgattacgt ggtgcttttt atgagagcct gaccgtgttg
     4681 gatgaaccgt ccgcgaagaa gaaaatcatg cgaacgcagg ctgccaaggt tttcgctgat
     4741 cacctcagcc gaaggggact gccccactct ccagagcgcc ttctgctttt taacagaagc
     4801 acgagcggct tcgccttcct agcacagcgc gtcatgaatg cgcgtgatgt cgtctacgtg
     4861 gaggagtata gctatcccgt gttcctgcgc ctgctgagcc agtgcggtat tacggttcgc
     4921 ccgattcgca tggatgaaga aggagtttgt attcaagccc tcaatgaaga gcaggagcat
     4981 tatcctgcca attggctatt gataaacccg cattaccaat tccctacagg catcagctat
     5041 tcattgaaac gaaaggaaga gcttctcgaa tgggcacaga atcataacgt acgtcttatt
     5101 gaaaacgatc attatggcga cctttggttt gaagagccga gtgttccgct gtaccagatg
     5161 gctgcgcagg caaaaagcac aatcgaggtc tactatttgc attctttgtc caaaacactg
     5221 gctcgcgatc tgcaattggg cgtgctaatg cttccttctg aattatcgaa tgatgaatta
     5281 gagcgctaca gccagcttgt ttccatgacc ggagcggaac cttccctgct cgtcgtagag
     5341 gcagccgttc aactcctcga tgatccatgg ttttacgaag agtttctggc agatcgacgc
     5401 gccctgttcc aggcccgctt cctgcgactc tggcaggaaa gacggcacgc actccccgat
     5461 cacgcacgga tgttcccaat cacaggcggg ttaaatacgt ggatcaaatg gggcacgcca
     5521 accgcaagag caaccgaaca agaagagaga gtcgtcgcta ttttgcgaga ggaaggtctc
     5581 gaactgactg gcggccatgc ttttcgcgta gcggatgagc ctgccgatat tctgcgatgc
     5641 ccggctgtcc gtttcccgct tgctccactg gaagaacgag agttgaaaca ttggctccac
     5701 cgattgggtg ctgctcttct tcggtaagtt ttccaaggga aatgccatac taacaaatgg
     5761 atttccctat ttccctttca ctagactcga aaaaagccga ggtataacct gctatgatta
     5821 aaaaaatcgt agaaaagctt caccttgatc caccaaaaac gcttgtactt gggtttgcct
     5881 tgattatctt cctgggagcg ctgcttttga cactcccggt cgctactgtg gatggacttg
     5941 gtctgcactg gcttgatgct ctgtttacgg ccacctctgc tacgtgtgta acaggcttgg
     6001 ttgtcgtcga tactggaacg actttcacga cctttggtca actcgtcatt ttatcgctca
     6061 ttcaaattgg cggtctcgga ttcatgacgt tcgctacatt cttcgcattg atcatgcgta
     6121 aaaagatctc cttgcgcgag cgactcatcc tgcaagaatc cctgaatcag atgtcgatag
     6181 aaggtatcgt acgtttagcc aaaatgattt tgatttttac tgcccttact gagtttatag
     6241 gcggggtgct tctctctatt cgttttgcct ttgattttcc tctgcaaaaa gcgatctact
     6301 tcggcttttt ccatgcgatt tctaacttta acaacgctgg ttttgacctt atgggcgagt
     6361 tcgccagctt gacagcctat gtggaggatc cgctcgttaa tctcgtcgtc tgtctgatga
     6421 tcattcttgg cggtattggt ttcatcgtgg tcagtgagtt atacgattat cgtcataacc
     6481 gccgcttgtc attacatacg aaagtcgtac tgacaacaac cggtctcttg attacagcag
     6541 gaacagtgct tatttttatt ttggagtaca acaatccaaa aacgttgcag cccctatcca
     6601 tgatgggcaa agtgctcggc tccttctatc aatcggttac accccgtacg gcaggttcca
     6661 acacattgaa tatcggtgac atgtatcagt cgtcgctttt cctcattatt atcctgatgt
     6721 tcatcggtgc ttcccctggc tcgactggtg ggggtatcaa gacgacgaca tttgccacac
     6781 tgattggtgc agttatcgcc caagtaaaag ggaaagaaga tgtcatcttc ttccggcaac
     6841 gcatcctgtc gcacatggtc tacaaatcgc tgacattgac tatgattgcc ctgttcattg
     6901 tgcttgtcat gacgatggtc ctctctatta ccgaaacagg ggcgcgcttt gagatggtcc
     6961 tgttcgaagt cacctctgct tttgctacaa ctggactatc catgggacta actcctaacc
     7021 taacacccct cggcaaagcg ttgatcattt tgacaatgtt tgctggtcgt ttgggacctc
     7081 tcacaattgc ctttgccctc gcgcagcgca agcagaagga atacttccgt tatccaaaag
     7141 ggaagatcac catcggataa accatataaa aaggataaaa ccctgccaaa gcacccgaag
     7201 gactttggca gggtttcgtt ttgtgtatga tttattgttt ttgccactgt ttggacagct
     7261 cgtcgcgaac cagttgaccc atctctactg tgccaatcgc tttgcttcgg tctgccgcga
     7321 tatcgccagt gcgatgtcct gcttccagta cggaccaaac tgcgttttcc acggctgctg
     7381 ccgcttcatc cataccgagc gagagacgaa gcatcatcgc tacggacaga atggttgcca
     7441 gcggattggc aatgcctttt ccagcaatgt caggggcaga gccatgaacc ggttcataca
     7501 ggccaaagct gcctgctgcc agactcgccg aggacagcat cccaatcgaa ccagtcagca
     7561 tcgctgcctg atcgctcaag atgtcgccaa acatgttttc cgtcacgatg acgtcaaact
     7621 gctttggttc tcgtacgagc tgcatcgcgc aagagtctac caactgatga gacagctcta
     7681 catctggata gtcggccgct actcgctcgg ctaccttgcg ccagaggcgg gagctttcga
     7741 ggacgtttgc cttatcaaca gatacgagac gcttttggcg tttgcgcgca atgtcgaagc
     7801 cgactcgaat gattcgctcg acttccgctt catgatagat gcactggtct tctgcgactt
     7861 caccgtttgg accgtcatag cgttttttct caccgaagta aatccccccg gtcagttcac
     7921 gtacaacgat caagtcaacg ccagaaacga cttctggctt gagggaggac gcatccacca
     7981 gagagctgtg catggtagct gggcgaatgt tggcaaacag accaagcgct ttgcgaatgc
     8041 caagcagccc tgtttctgga cgaagatgcc caggattctg atcccacttc ggtccgccaa
     8101 cggctcccaa gagcacagca tccgcttgct ttgccagcgt taccgtttct tctggcaacg
     8161 gtgttccatc cgtatcgatt gcgataccac cgatccggcc ttcttcacat gtaaaagtaa
     8221 caccttcaag ttcccctacg agtgtaagga ctttaaccgc ttcctgcatg atttctggtc
     8281 caataccgtc tccaggaaga acggcgatgc gatagttttt cttcatcgtt tatcccgctt
     8341 ttctatacgt aatggtttcc gaacgctgct ggttcctatg atcctatcca catttgaccc
     8401 tatctttata tcgttgcact gacgggcgca ggctcgccac gccgctccat gatcttgttg
     8461 actgcccgta cataggcaat ggcgcttgct tccagcacat ctgtactcac accgcgtccc
     8521 gttacaatca gatcgccctg ttgaaggcgt acaaacactt cacccaacgc atcttgcccg
     8581 tgagtaacag aaaggatttt gtaatcgacg agggagactt cttctccggt agcgcggtca
     8641 atcgctttgt agatagaatc aaccgatcca tttccacatg cggcttcttc gcataccgat
     8701 ccgtcggcac gaaccagtcg tacactcgct gtcggaacag aaatgttgcc ataagcgagc
     8761 tgtacggatt ccagctggaa cgcttcaggt ccgcgaacca tcttggagtc gaccaatgcg
     8821 aggatgtcgt catcggtgat ttctttcttt ttgtcgcaca atactttgaa cgctgcaaac
     8881 gctgcgttta cctcttcttg ctccaggtga tagcccagat caaccagctt ttctttgaat
     8941 gcatggcgcc cagagtgctt gccgagaacc agtttgtttg acttgaagcc gaccgattcc
     9001 ggacggatga tttcgtacgt agtgacttct tttaacacac catcctggtg aataccggat
     9061 tcgtgcgcaa aagcatttgc acccacgacc gctttatttc ctggcacgat catcccagtc
     9121 aaacggctca ccagctggct ggtccgtgcg atttctttca aattcagctt ggtcgtcgtc
     9181 tggtagtaat ccttgcgagt ctccaatgca agagccactt cttccagagc tgcatttcca
     9241 gcacgctctc cgattccatt gatggtgccc tccacttgcg tagctccacc ctcgacagca
     9301 gcgagactgt tggcgactgc catcccgagg tcatcgtggc aatggcagct cagacgaatc
     9361 agatcagtag aaggcacgcg ttttttcagt tcacggaaaa tgtttccgta ttgatacggc
     9421 gtcatgtagc caaccgtatc tggaatattt accgtggtag cccctgcctt gattaccgcc
     9481 tctacaacct ctgccaaaaa gtcgatctcg gtacgcgctg catcctctgc ggaaaactga
     9541 acttccgtaa agtacttttt cgcataggta accgcctcca ccgcccgagc aaggacttct
     9601 tccttgctca tgttcagctt gaactgacgg tgaatcggag atgttgcgag aaagacgtgg
     9661 agggaagcgt tttgtgcgtt gcgaagcgct tcgtatgcct tatccatgtc gtcttttacg
     9721 gcccgagcca gactgacgac ggttgcattc ttcacccgtt ttgcaacttc ggccacagac
     9781 ttttggtcac caggagaggc agcagcgaag cccgcctcaa ttttgtttac gcccagcttc
     9841 tcgagttgaa gggcgatctc caccttttcg ttcgtgctaa tattgacgcc cggagactgc
     9901 tccccatcgc gcagtgtcgt atcaaaaatc tcaatggtcc gcatgaactt ttcacctcca
     9961 catttttccc tacattatat atagattttt tacacggcaa ttattggccg attttcgctt
    10021 cttctttttt cgtatctttg ttgatccaag acatcatgcc gcgcagctgc tcccctacta
    10081 cctcgatacc atgctcggat tccaggcggc gacgggaggt gaagccagga cggtttgctt
    10141 ggttttccaa gatccaattg cgagcgaatg taccgtcttg gatttctgcc agtacttttt
    10201 tcatttcttt gcgtgtttca tctgtgatga tgcgacgacc tgtgctgtag tcaccgtact
    10261 cagctgtgtc actgatggag tagcgcatac gagccaagcc accctcgtac atcaggtcaa
    10321 cgatcagctt cagctcatgc aagcactcga agtacgcgat ctcaggagca taacctgctt
    10381 ccaccaatgt atcgaagcct gcttttacca gctcgcttgc gccaccacac aatactgctt
    10441 gctcaccgaa caggtctgtt tctgtctctt cacggaaaga tgtttcgatt acgccagctt
    10501 ttgtgcaacc gataccgctg gagtatgcga gtgcgagatc tttcgcgttg ccagttgcat
    10561 cttggtagat cgcgatcaaa ccaggtacgc cgaagccttc ttggtatacg cgacgaacca
    10621 ggtggcctgg gctttttggc gctgccatga ttacgtctac atcagctggt ggcacgattt
    10681 gcgcgtagtg gatgttgaat ccgtgagaga agcacagtgc agcgccggat ttcaggtttg
    10741 gcgcgatctc gtcgcggtat acttgtgctt gacgttcatc tggcatcagg atttgaacca
    10801 cgtcagcgcg tttggttgct tctgctacag tcaaaacttc aaaaccgtct ttcgctgcaa
    10861 catcccaaga tttccctggg cgcagaccca caactacttt atagccgctg tcgcgcaggt
    10921 tttgtgcttg tgcatgacct tggctaccgt agccgatgat tgcgattgtt ttcccacgca
    10981 gtacctcttg ttttacgtcc gcttcatagt acatttttac catttgtata gcctccctaa
    11041 aaatgtttag tttgaatttt tattctgaaa ttttgcaatt taaaccgttg cagcggctgt
    11101 tgctggaaca atactgcgcg ccatcgctac tgaacctgtt cttgtcagtt caataacgcc
    11161 gtagctttgt aatagaacga gcagcgcatc aatcttttcg gtgtcacccg ttacctgcac
    11221 gatcagtgag ctagggccca catcgacgat cgcggcacgg aacggctcga caattccatt
    11281 taactctgcc agctggctgg gcgatgccgt cactttaatc agtgccagtt cccgtgaaac
    11341 aaaagggttc tcgctgagat tcgtgacgga gatgacatcg atcagcttgt gcaattgctt
    11401 catgagctga ttgatttggc ggtcatctcc cccggttgaa atgatcatcc gggacaggcc
    11461 ctgttcttcc gtgcctccca ccgtaatgct gtcgatgttg aagccgcgtt ggccgaacag
    11521 tgtggccact ctggtcaaaa cgcctggctg gtcgttgacg agtacggaaa tggtatgttg
    11581 ctgcatccta atcgtccccc aattccatct gatctaatgt gtcgcctgat gcaaccatcg
    11641 gatatacgtt ttcttcctgt gctactcgga agtccaccac gactggtcca tcatgcgcaa
    11701 gcgcctctgc ccaaactgct tcggcttcct ccggcgtact tgctcgcaag ccttttacgc
    11761 catatgcttc cgccagcttg acaaaatctg ggctgcacgt cagatcgatt tggctatagc
    11821 gattatcgta gaagagctcc tgccattgac gaaccattcc caagcactgg ttgttcacaa
    11881 tcgctacttt aaccggaatg ttgtattggg agacgattgc cagctcttgg ttggtcatct
    11941 ggaatccgcc atccccaacg acagagatta ccgtgcgatc cgggtgagcg atttgtgcgc
    12001 caattgctgc cgggaagccg aagcccatcg tgccgagacc accggaagag ataaaggaac
    12061 gcgggtgctt gaacttatag tattgagctg tccacatctg gtgttgtcca acatctgttg
    12121 tgacaatcgc ttccccatct gtggagttgt acaagagttc aatgacggct tgtggcttca
    12181 atacgtcgcc atcttttttg tacttgtacg gatattgttt ttgccactct ttcaactggc
    12241 tgatccacgc ttccgaatca caagtttttg cgagcggaat cgcttttgcc agcgtgctct
    12301 ttacgtcgcc cgctactgtt acagctgtgt ctacgttttt ccccagctct gccggatcga
    12361 tgtcgacatg tacgatgcgg gcttttggtg cgaactcctt ggtgcgtccc atcgtgatcc
    12421 ggtcatcaaa gcgtgctccc agaccaatca cacaatccgc atttaagagc gcttggttcg
    12481 ctgtgtaatt tccgtgcatc cctggcattg ccagcgacaa ctcgtgtgtt ccagggaaac
    12541 cgcccaatcc catgaaggtg ttgatcaccg gaatgcgtgt tttttctgca aagtcgcgca
    12601 attctttctc tgcttgagct gcaatgattc ccccgcccgc caaaatgact ggacgcttcg
    12661 cttcgccaac tgcttttaca aactcttgta cttcttcgtc gcttggtacg agtgaagcgc
    12721 ggtagccgcg aatctccact ttatccgggt aggtaaatgg tgccttcgca ttggcgacgt
    12781 cttttggaat gtcgatcaat actgggcccg gacgaccggt cgtcgcgatg tggaaagctt
    12841 ccttcacaat ccgcgggaga tcgcgaatgt cgcggacaaa gtagctgtgc ttcgtaatcg
    12901 ggatggtaat tcccgtaatg tttgcctctt ggaacgcatc ggtaccaatc agcgactgtg
    12961 ccacgttacc tgtgatgcag accagcggaa ccgagtccat ctgagcggtt gcaatccccg
    13021 ttacgaggtt cgttgctccc ggaccggaag tagcgataca tacacccggt ttgcctgttg
    13081 ctcgggcata tccgtcagca gcatggatag cgccttgctc gtggcgagtc aaaatgtgct
    13141 tgaagtagct cccgtacagg gagtcataaa tagggagcac cgcaccgcct ggatagccga
    13201 aaatgtattc gacctgctcc aggatcaaac agcgcagcag cgtttctgct cctgtcactt
    13261 cttccccgaa ctgaatcggt ggaatgccgt tctttttctg caattcggcc atttcaacac
    13321 tcattaacct ctcctcctcc caattctcaa caggtattga aaataactat agacacatag
    13381 aaaaaccctt tcgccccgac acggttttat ttccatgtct tttggggcga aagggttcgc
    13441 ggtaccaccc aactttatcg gcgcctcacg gtcagccgat ctcagccagt cacagcaaat
    13501 gtggactgta acacgttaac gggtgttaag cggtttggcc tactacctgc aaagcaagtt
    13561 tcagctaaac ggctcggagg tgagcaatgc ggcgtaccct atacccgttt ctcagcatca
    13621 gggctctctg taaaaggggt aacgcgcacc atcctcgtca tggcctacta tttaaacaat
    13681 attttcaata ttgttgttgt cagaataaag tgttacgtct gattatagct aggcacctag
    13741 ggggtgtcaa cgaaaacaaa aagattttac tggactttcg tccgaacgaa tgctcagtaa
    13801 gaaatggcta tacggcgcgg tttttgcttg aaagcggata caacaaaacg gtcaaaaccg
    13861 ttttgttgac cgcaagcggt cgctatactt ttatgaaaaa cgtcgagacg tttttcactg
    13921 aaaactggaa agcttgtcca gtttttgcaa cggaaaaaga acggcattgc cgtccctctc
    13981 ctccttttcg gttccgtttt attgcgggga tttcaatcct tctatcaaaa tcgttgcgac
    14041 ttccggacga gtaaattccg gaggtggcgt gatcccgttt ctcaacattt ccctcacttt
    14101 tgttcccgat aaggtcagat gagagtcttt gtcatgcggg cacgtcttgg tcgttgccat
    14161 accttggcat gccgtgcagt aaaagctgtg ctcaaaaaag agcagctgga taccgagctc
    14221 gcctggcgca aactcggaaa agatgtgctg cgcatcatac gtcccgtagt aatcgcctac
    14281 ccctgcgtga tcgcggccga cgataaagtg tgtacaaccg taattttttc gtaccaatgc
    14341 gtggaagacc gcctctcgcg gacctgcata tcgcatggca gccggaaaag cgccgagcag
    14401 tacacggttg tgcggatagt aattttccaa aagggcgaga tagcttttca ttcgtacttg
    14461 tgcaggaaca tcgtctgact tcgtttcccc catcagtggg ttgagaaaaa ggccatcaac
    14521 aatctccaat gccgcctttt gaatatattc atgcgcccgg tgaacgggat tgcgcgtttg
    14581 aaaaccaacc accgttttcc agccattttt tcgaaatcgt tctctcgttt cagccggcgt
    14641 caaataaaaa tcagagaagc gctcaggccg tggcttttgc agtacttcta cggggccacc
    14701 cacgtatagg tttggctttt caaacagttt tttcacacca gggtgagcga gatccaccgt
    14761 acgaaaaacg agctctgcct cacgcatttt atctggcaca tagcagctat tcacccgcaa
    14821 aatcgcataa tccactccat cttccccacg tagcagaata ctgtcgccag gcacaagatc
    14881 atcgtgctca tctgcatcga cagccaatgt cactggcaac ggccacaccg ttccattggc
    14941 tagacgcatc gtttccacga cagtgtggta atccgcctct tccatgaatc cagccaacgg
    15001 cgaaaatgcc ccgatagcaa gacattcgat gtccgacagg gtccatttgt ccacgataat
    15061 ggcttttttg atcccgtgcg gcaagatcgt ttgtttcacg tctttccctc ctgcgctgtt
    15121 catttgtgca gaccgcattc tgtcttttcg aagccagccc accgtcccga ccgagaatct
    15181 tggccaggca tgacagcgcg cgtgcatact cgacagccaa tgcttggata gttccggtcg
    15241 tgcaatggat tgtaagggac atcatgcgca tggatatatt cccacacctg ggcctccgtc
    15301 caatctgcta gcggattgaa tttaaccagg ttgaattttt cgtcccactc cacttttttg
    15361 gtattcgctc gggtaggtga ttgctcgcgg cgaatacctg taatccacgc ctgatagttg
    15421 gacaggacgc gctttaacgg ctctaccttc cgaatctcgc agcaaagatt cggttctctc
    15481 tcccacagtt tttctccgtg tttttctgcc tgctcggtta gcgtcaactg tggctgcact
    15541 tgaataaatg ttgtgctgta tctggcttgc agcttgtcac gcgtatcata cgtttcagca
    15601 aaatgaatgt tggtatcgag gtaaaataca ggaatcgtgg gagccaattt gtgctgcatg
    15661 tcaattaaaa cgacatcttc agcgccaaag ctggcagcta ggatcagact agctgcatag
    15721 ttttccacgg cgttcacaag cacgtcctgc ggcgcgtgag cttccagtcg gcttgcccat
    15781 tcctgtattt cctcatccgc cattttctgg cgattgctca tcagcgaaac tcctctcttg
    15841 ctaggattca cccaccatca tatgcctagt gactggaagt ggcgcatcgt ccacccatat
    15901 ccaactcgcc caaaccaaac cgtcatgacc gtttggttga ccgcaagcgg tcgtatccac
    15961 ttttttgaaa aatgtcgaga tgtttcgatc ccccgatgag aggggacgtt tttcacagaa
    16021 aaaaagccgc cagacatggt ctgacagctt tctgctgcgt tatttttcat ctttttcgtt
    16081 tacagccggg gcgaaaataa acgaaggacc gatttgttgt gtctttttgg tatcggttac
    16141 tttaacggtt tgaacggttg gtatcgcata tgaaccaggg cttacgaagg aaggcggcac
    16201 cgagtaagaa tcatccttgt ctttcgcaaa cgctcctggc acaaacaacg ctgaacaaac
    16261 tactgctgtt acacccatta tcatccattt ttttctcatc tatttctctc tccctatcca
    16321 atgttttcct gtaacgcttt ttattgtatg gcattgggga gtctgcttga cacggacgaa
    16381 agattgtttt tttctcagac ttgaggttta catccacttg gtaccaaaga aaaagcatcc
    16441 tgtacggatg cttgaagccc attagttttc ttctttttcg tttacaattg gagtaaaagt
    16501 aaatgcactt cctgctgttt gcgtgcctgc taccgcatct gttttctgta ctactggagc
    16561 cgagtgcgga ccaggggcga agatagaagg cgtcacggaa tatgagtcat ctttgtcttt
    16621 ggcaaacgcc cctggcacga acatcgctga acaaacaact gctgtaattc ccatcatcat
    16681 ccacttttgt tttctcattt tgatctctct ccctatccaa tgttttcctc ttatggcttt
    16741 attttaaggg atcagccatg ttgtctaaca cggacgggag gttgttttct cctcagacct
    16801 ggggcggatt ctgctttagg accagagcct agttctacag cgaattagca gttctatttt
    16861 cctctttttc aaaatgacag aaagcattta tacaaaatat ggtatgattt tgaattgtgc
    16921 tgattttcat ttgacaggag gtaaccgcat gtccaagctc agaggggtat tgctttctgg
    16981 attgttgctc attccgattc tatcgggctg tagccaggaa gccaagcccg ttgaagccga
    17041 gtccgggcaa acccagaacc agccgtcaac acagactacc actgctcctg aaccgacggc
    17101 agaaacgaaa gcaaaggaag aagccaaacc agagggtgaa gctgtaaact tcgaagtcgt
    17161 tggccagcca tctagcgacg ctccagcaga ccaaggagat ccaaaagcca ctcttggagg
    17221 ggaactcacc atcaactcca agacattgac gatcaaagga tcatccaact tgctccccgg
    17281 tgcaaaagta aaagcaaatg taaccgcaaa aggctataat atgtggggtt ataacgatga
    17341 gacggaggtt aactccgatg gaagctttga actggaggta aaaaagccag acgtgaaggc
    17401 acagatggaa gtcgaattgt ccttcacctc cgatcagcaa agcgatcgaa tccaagaagc
    17461 ctatggtaaa accggcgaaa agctaaccgg tgattacgtg tatcaatacc tcgattctga
    17521 caagttgaaa tacaaagtgg cgacctttgc ctatgtcgac ccgaaagcac agacaaatac
    17581 gaaggtgcca ttcgaaacac ctgtatggga taaaccatct gattatggtc aacctgctat
    17641 ttggatcaag ccgagcataa ccaaaaacgg gaaatcccta accgtagcgg caaaaagcaa
    17701 tttcctggaa gggactaaga taagtggtgg tctcgatatc cctaaccatg tccattatgg
    17761 ctatacagat cagactgagg ttaaaccgga tggatctttt tccctgcaaa tcccccagcc
    17821 tgacaaagtt aagcaatatt acgtccttat tcaattcata ccagacgaca atatgtggcc
    17881 aactgtaaag gatgcctatg gggaaaaagg tgaaaaatta aaaggcgagt tcatcaaaat
    17941 caaagactca gacaaaaaaa cagtcaacat gattgaaatg aagatcaaag tggatctata
    18001 ggcatgaaaa aaagcacccg ttgtggatgc tttcgcggtc gaattcgttc gatcgccttt
    18061 tttttcttac acatcgatcg ttgttcttgt atgcttatac agctcttcaa tcgtctgccc
    18121 ttttgctcgg gcaagtacct ccatgcgcac actcagttgc tttttcgcaa actgctgcaa
    18181 atcagcgacc ttcactccga atgcactcac tccttgtggg tcatccatcc agtcgtacag
    18241 atgacttgcc attggagcca gctcatccat ctttttggca atgacatcgt aaatatgggg
    18301 atgctcacag atcaatcgct gcagcaggaa tgttccgtag ctgatatgcc gcgattcgtc
    18361 tgtctttaaa tacccgattc cttgcattaa accgggcatg agccctgttt tgctgagtgc
    18421 ttcgtaaaac gcatagtagc ctgtctctgc gagcacgcct tccacaaaca tgttgtagac
    18481 agtagaagct tctgcgatgg cttcagggga tttatccgtc agcagacgat tgagtgcatt
    18541 tggcaagatc tcatggaaaa ttcgtttgta cacatcatcg tgaaaatgat gcaagtctcc
    18601 tgactcgccg atattatcga gaaccaaccg aaaaaactcc gtatgcttgg cctcttcaaa
    18661 gaggaaggtc gtcaaataca tttcttcctc caatcgccct tcctctgcta tgaccatgat
    18721 caaaggcaaa agatcgaggg tgacagcttc ttccccacca agaaaaccag caatccgccc
    18781 caaagtttct tccttctgct ccggattcat cttcgcgtaa tcttcacggt cttgcgtaaa
    18841 atcaatgtcc tgcgggttcc aaatgccgta tctcttcgct ttttgataca attggtacgg
    18901 cagcagctcc tgattcaatc ctttttggct ggtcgaaaca aaaccattcc tcatccccat
    18961 ccaacctttc ttttttctca tacgccttct attccgaacg aatgaaagaa gtcacgaaat
    19021 tgttaattta tcccatttcc attctttacg ctccgatcag cggtttgata aaatgaaggc
    19081 gctgtaggtt gattataggt caggctgaac gatcgttcat atccccaaaa atcagggggt
    19141 gttcatcacg caaatggagg tggcaatcac tccatggtca gtccagagct gaacatgtac
    19201 atcgatcgaa tcgaagaaac gacattttac gaggagaaac tggtgcttgc tgtacgcggc
    19261 ttcgtggatc tctttccttt tatgggagcc attctgtgca attactcgac gctcagtcaa
    19321 atgggtgagg gactatggtc gatccttgac caagagttat gctctatccg cgatatacgg
    19381 gtggacatgc gcaatatgcc cctcatccag catgcgatcc gtgaacagag agccgtcctg
    19441 ctagattctg aggcgattcg tcagttcccg cccgatttag tgtacggcgc cccttatgca
    19501 ctcattctcc ccatcagcta tgggcctaac gtactcggct acgccggtat ttcctggcat
    19561 caggatggct gttccggcat caaccatcaa ttggtacaat ccttaagcgc atactgttcg
    19621 atgctgggca aagtattggc aactgactcc cttcgcccta aaaccgtcaa gctctcacgg
    19681 cgagaagtcg aagtcatgca gcggatgtca tggggcgaaa gcgttaagga gatggcggac
    19741 tggatgggaa tcagtgagtt taccgtgcag gattacatca agtccgcctt aaaaaagctc
    19801 ggtgtgcaaa atcgcgcaca aggtgtggcg gacgccataa gacagcgaat catttgttga
    19861 gtagaaatgg aaaaaacaac cgaatgtgat ttcggttgtt tttctttggc tcgtaatcca
    19921 aaactcgaca gtacgtcatt gaattcaaga gcatggcact gtctgactac taccccacgt
    19981 ctgacgaaaa tggattgata atcacaacaa aaaagccgac ctcgccctca atcgggaaga
    20041 tcggctcttc tattcaaaaa ttacgcgttc agtttgcctt tagcaactgt tgccagttcg
    20101 ttgaacgcag ctttgtcgtt aacagccaag tcagccagca ttttgcggtt aacttcgatg
    20161 ccagcaactt tcaggccgtg catcaaacgg ctgtaggaca gaccgttcat gcgagcttgc
    20221 gcgttgatac gagtgatcca cagtttgcgg aaatcacgtt tcttttgacg acggtcacgg
    20281 tatgcataca gcagggattt cattacctgc gcattagcgg atttaaacag gcgatgtttg
    20341 gaaccgaagt atcctttcgc cagcttcagg attttcttat gacgacggcg tgtaacaatg
    20401 ccacctttta ctcttggcat actaaactcc tcctggtctt tccagcatgg cggcctactg
    20461 ctaggcgctt agggagctca tgctgcgtaa tggtgtgtaa taaagaaaaa cttacaggta
    20521 agtgagcatt tgctcaatac gtttttgatc gcctttggaa acgagtgcag ctttgcgcag
    20581 gtggcgctta gctttcgtcg atttgttagc gaacaagtgg ctaccaaacg cacggtcgcg
    20641 cttcaattgg ccgcttccag tctttttgaa acgtttcgca gcagccttgt tggttttcat
    20701 tttaggcatc tgaaaaatcc tcctgtctaa actactatct tacttttccg ctttcggagc
    20761 cagaatcatg atcatgctgc ggccctcgat cttcggcttg cgctcaggcg tagcgagatc
    20821 ttcacactgg gcagctacac gttccataac gcctagtcca atttcggagt gggtgatttc
    20881 acgtccacgg aaacggatcg tacacttcac cttgtgttga tcctccaaga acttgcggac
    20941 gttgcgaagc tttgtttgaa aatcgtgttc ctcgatgtta gaagaaaaac gcacttcttt
    21001 cagctcgata atcttctggt ttttacgcgc ttctttttcc tttttcgcct gctcgtattt
    21061 gaactttcca tagtccatga tacggcatac aggcggcttg gctgtaggag caacgtttac
    21121 cagatccaat tcagcttcct gggcaatgcg caacgcttcc ctaaaaggta cgactcccaa
    21181 ttggctcccg tctgcaccga ttaatcggac ttcacgggca cggatcgctt cgttaattaa
    21241 catttgatcc ttgctaatac ttgccacccc cgtcaatttc gagaaggaac aaaaatgtgc
    21301 gaacgcaatc tgcgcccgca catatctcac ctaagcaatt tcatcagatc cgaggatctt
    21361 tgcgtaagag ttacctgtca acagtcgtat acgacgtcga cccaggtgag aagctgggcg
    21421 cctctgcttg ttctcgaagt atgaagtgtt tatacacgca atttatatta ctaggtagct
    21481 tgggttttgt caaggctaat acctaattat cccccgatat gggacatttc gaccttttca
    21541 cgcttggcga gaccaggtgt ttcacttagg cgttcctccg agtagcgcac gtcacgccgc
    21601 tcccaaatcg cacgtatcag ctcgcgaatc tcttcatccg tgcgtccatc gcggactggt
    21661 tcgcgcaaat catctccgga tgaagcaaag agacagttgt acaattttcc ttctgccgac
    21721 agacgagctc gcgtacaagt ggagcaaaaa gcttgggtca ccgatgagat caacccgatc
    21781 tcctggttcg atccctcata gcgataacga gaagccacct ctccatagta gttcgcttca
    21841 gtcgctacca acggcatctc ttcatggatc atgcgcacaa tttcacggga aggtacgact
    21901 tgatccagtc gccagccgtt actgtttccc acgtccatga attcaataaa tcgaagggtg
    21961 tgcccttgct cacggaagta ccgtgccatc ggtaaaatat cttgatcatt gactcctcgc
    22021 tgtaccacca tgttgatctt gatcgatagc ccggcatctg ctgcaacacg aatcccttcc
    22081 agcacggcat cgacctgata gcctcttcca ttcaacatcc caaagcgctc attatccaag
    22141 ctgtccaggc tgaccgtgac ccgatccaga ccggcttctt ttagtgcttg cgcatggcgg
    22201 gtcaagagag aaccgttggt cgtcatcgca atatcttgaa caccttccac tccacgtatc
    22261 attcgaatca attcaggcaa atttctgcgc attaatggct ctccgccggt aatgcggatt
    22321 ttcccgaccc caagcgaagt aaagatctgg gtcaaacggg taatctcctc aaaggtcagc
    22381 aacttgcttt gcggcaaaaa ctcaaaatcc ggtccaaaaa tttcggcagg catgcaataa
    22441 cgacaacgaa aattacattt atcagtgaca gatattcgta aatctcggag aggacggttc
    22501 cgtaaatcaa gcactttttc tggcatagat gttcactctc cttttatcta taggacgact
    22561 tttttccctt atctttataa tatcgcattt cgacttagta ccagtctatt atcataaatc
    22621 gaaatagcca aattttcaaa cgcaaacagc acattgttca taaatgggac cactttacaa
    22681 aaaaaagagt acgaattcct ccctacattc gtactctttc cgttatgcat tcttatatct
    22741 taaatgtact gatcattctt tccagttcgc gagccatctg attcaaagat tcaaatgaaa
    22801 cagcaaactc ttccatagta gccaattgtc ctttggagga agcagccaga ttttcagcat
    22861 tgtgcgctga aatccttgca atttgggcag tctcgtccac tgatgctgct acttgttccg
    22921 atccagcgga catctgctca gagacagcag atacctcctg aatttgatcg gttatctgtc
    22981 gaatttcttg taagatgcgt tggaaggcct ctcctgactc cagtacagta gacaatccat
    23041 cctgaacatc ttgattgact gaatccatcg agttgaccgc tatggtcgta tctgtttgga
    23101 tctcctgaat gaggttggcg atttgccgtg cagactcatc agattgttca gcgagttttc
    23161 tcacttcatc tgctacgaca gcaaaacctc gtccatgctc tcccgcacgg gcagcttcga
    23221 tggctgcatt gagagcaagc agattcgttt gggaagcaat tcccgtaatc acgtcaataa
    23281 tttgcacaat ttctttggat cgctcaccca attgcttgac tacg
//
