LOCUS       c00010_NZ_CABK..       17283 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTM010000013.1 Anaerosalibacter massiliensis isolate
            MGYG-HGUT-01473, whole genome shotgun sequence.
ACCESSION   c00010_NZ_CABK..
VERSION     c00010_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:40:11
            Original ID  :: NZ_CABKTM010000013.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17283
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17283
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4165:7283]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Fe-ADH, Fe-ADH_2, HBT, Mal_decarbox_Al])
                     and cds(HpaB_N and HpaB) and not (LAM_C or BKACE))"
                     /neighbourhood="10000"
                     /product="aminobutyrate2Butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4166..7283
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Fe-ADH, Fe-ADH_2, HBT, Mal_decarbox_Al])
                     and cds(HpaB_N and HpaB) and not (LAM_C or BKACE))"
                     /neighbourhood="10000"
                     /product="aminobutyrate2Butyrate"
                     /protocluster_number="1"
     cand_cluster    1..17283
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Fe-ADH, Fe-ADH_2, HBT, Mal_decarbox_Al])
                     and cds(HpaB_N and HpaB) and not (LAM_C or BKACE))"
                     /kind="single"
                     /product="aminobutyrate2Butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17283
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="aminobutyrate2Butyrate"
                     /region_number="1"
                     /rules="(minimum(2, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Fe-ADH, Fe-ADH_2, HBT, Mal_decarbox_Al]) and cds(HpaB_N and
                     HpaB) and not (LAM_C or BKACE))"
                     /tool="gutsmash"
     CDS             complement(3..830)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.8e-54, bitscore:
                     177.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFEVTVIGGGPGGYATAIKSAQRGKKTCVIEKENFGGVCLNEGC
                     IPTKTLIKTINVLEEIKRSSEFAIEGLDTKNVKVSMEKLQKRKEMVRKQLVGGTESLLE
                     SNGVEIFNGEASFKDKNTVIVNGKEITSENIIIATGSKTAEARFIERIGETNIITSKEA
                     LELEKIPKSISIIGGGVIGIEFAYIFSKLGTKVTVLELMDRILPMVDEEISNILKRNLE
                     KSGVKIINNARVKSVNENTVHYEFKGKEEFVISEYTLLSIGRTPNTENLNLEAV"
     CDS             complement(845..2161)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 56; E-value:
                     9.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_2"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-17, bitscore:
                     56.0, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 4.1e-81, bitscore:
                     264.9, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVVIMPKLGFNMDEGKLVKWHKSEGDSVSSGEVLFEIHTDKTT
                     MEVEAVTDGIVLRLLVEEGEEMPVFTPIAIIGESGENPDEILRKYNEENGIETDEESGE
                     EEIVEETENIEEVVIDTDLKLTPRARRYVKENSLDINSIKNIEGTGFRGGITEKDIKVS
                     PIAKKLAHKLGLDISTVEGTGVGGKIVKDDVQRKSNILQEDHTKRVKDTIPYSGVRKII
                     GDRLSESKFTAPHLYFSNDVDTTNLTKFRKELNENSDLKISSTDLLVYALGKALKKYPE
                     INASLVGDVIEQYESINIGIAVAGNNGLVVPVVKNIQEKTIQDVAKETKDLISRARVGK
                     LLSEEYNGGTFTISNLGMFGIDSFTAIINPPELAILAVSSINKKPVVKTNEDGEDVILI
                     RPMMNIQLSVDHRIIDGLLAAEFLGYVREILENPIKILM"
     CDS             complement(2183..3157)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="Transketolase_C (E-value: 9.6e-36,
                     bitscore: 115.5, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.7e-57, bitscore:
                     187.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNIMYRDAILEALDEEMARDENVFVMGEDVGTIGGNFKCTAGLL
                     EKYGDLRVKDTPISESGFVGLGIGAAITGLRPVVELMFGDFMMVAMDQICNQAAKITYM
                     SGGQVRVPMVIRMPIGGGRSSAAQHSQSFYAWAAHCPGLKVVVPSTAAEAKGLLKTAIR
                     DNNPVLFFEHKMLYTEKFDLTSDEDYTIPFGQARIVNEGDDITIVATSMMLVKTEKVVK
                     KLKQEGINVELIDPRTLVPFDKETIIKSVEKTGKLLIIDEGHKSYGISGEITMKIMDDI
                     FYSLDAPVKRLGTADVPLPFSPALEFPLIPDEKDIEKAIREMI"
     CDS             complement(3201..4154)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_4"
                     /sec_met_domain="E1_dh (E-value: 7.4e-89, bitscore: 290.6,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDNKKVLAKKFYEVMYRMRRFEEEVFEFYKKGMMPGLAHLYLGE
                     EAIATGACAALDKNDYIASTHRGHGHLVGRGADLNKMMAEILGKKDGYSKGKGGSMHIM
                     ALDKGILGANGIVGGGIPIATGAAYKSKYKESGEVTIAFFGDSASNQGTFHESINMASA
                     WDLPIIYIIENNCFGISVDIRKVTKEHQLSKRSVGYGIEGVTINGNDVFEVYETVSKAV
                     EKARKGGGPTLIECKTYRWQGHHVGDPATYRDKKELETWKAKDPIKNLLKLELIDEREI
                     NEIEEKVENEIKEAVKFAEDSPYAEIEEAYTDVFVD"
     CDS             complement(4166..5464)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminobutyrate2Butyrate: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminobutyrate2Butyrate: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_5"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 5.4e-69,
                     bitscore: 224.1, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 5.1e-34,
                     bitscore: 111.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEWRKIYDSKLVTPEEAVNQIKSGDRVVVGHAVGEPQTLIDAMVE
                     NKDCYEDVEIVHMVAMGKSKYVEKGMEKHFRHNSLFVGSTTREAVKEGRADYIPVFFSE
                     IPSLFRELLPVDVALIQVSSPDEHGYCSFGVSVDYTKEACKRAKLVIVQVNKHMPRTLG
                     DCFIHVSEMDFIVEKDEPIIELIPPKIGKIEKEIGRHCASLINDGDTLQLGIGGIPDAV
                     LSCLYDKKDLGIHSEMFSDGVVDLVNAGVINNSKKTYFKNKMVATFLMGTKKLYDFVNN
                     NPMVEMRSADFVNNPVEIMKNDNIVCINSCVQVDLMGQVVSDSIGSMQISGVGGQVDFV
                     RGASMSKNGKSIIAMSSTVKGKVSKIVPVIDKGAAVTTSRNDVDYIVTEYGIARLKGKN
                     LRQRAEALIEIAHPDFRQELREAYLNKYNIKNS"
     CDS             complement(5489..5773)
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MELRYKIEKIIEKDIRPKLRLHGGDIEIKSLVDKELVIRLTGNCK
                     NCPSAQMTTEDIVERILRENLGSEIGNIKLDSSVDEDLISFAKKILKIN"
     CDS             complement(5820..7283)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminobutyrate2Butyrate: HpaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminobutyrate2Butyrate: HpaB_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_7"
                     /sec_met_domain="HpaB_N (E-value: 1.2e-111, bitscore:
                     365.8, seeds: 158, tool: rule-based-clusters)"
                     /sec_met_domain="HpaB (E-value: 2.4e-77, bitscore: 251.6,
                     seeds: 147, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIKTREEYIESLRKLDLKVYMFGELIENPVDHPIIRPSMNSVAM
                     TYELANQDEYKDLMTAISHLTGEPINRFCHIHQSTEDLVKKVKMQRLMGQKTASCFQRC
                     VGLDAFNAIYSTTYEIDKKYGTDYFERFKEYLKYVQKNDLTVDGAMTDPKGDRGLSPSE
                     QEDPDLYLRVVEVREDGIIVKGAKAHQTGAVNSHEQLIMPTMALKEKDKDYAVSFAVPS
                     DAEGVFMIYGRQSCDTRKLEDGADMDLGNAEFGGHEALVVFDNVFVPNERVFMCKEYDF
                     AGMMVERFAGYHRQSYACKTGVGDVLIGATALAADYNGVPKASHIKDKLIEMIHLNETL
                     WAGALACSYEGIETESGNYLIDLLLANVSKQNVTRFPYEIARLAEDIAGGLMVTMPSEQ
                     DFKDPKIGEYVEKYFAGKTGTSTENRLRILRLIENITLGTAAVGYRTESLHGAGSPQAQ
                     RIMISRQGKLEDKKEMARIIAKVDYSKDK"
     CDS             complement(7574..8998)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MKNNLSTYENLSREDILKILKSRDRELYKFKTLFDHLAEGVYMTD
                     CNTKTLYVNTAYEKLSDNSREHFIGKTIYQVLDEKLIDESGTLLAIKNRKSISIQQKLA
                     NNKIALITSTPIINDKDELEYVVTIVRDITEIMNLREKIIEREREIQKLKSQKERAMNF
                     MYKSHETEIILEQSKKVAKYDSTILITGETGTGKGAMAEYIHKNSNRSDKKFIQLNCAS
                     IPASLIESELFGYEKGAFTGARDSGKIGIFEQAHGGTLFLDEIGELPLSMQSKLLTVLQ
                     DKKIRKIGSDSEIDIDVRIITATNRDLNSMIEAGKFREDLYYRINVVPIHIPPLRDRRE
                     DITALTKEFLREINEKYNIDVDIDSEAFHTMYYYDWPGNVRELKNLIERLFVFAKNNTI
                     TKEDLPQSMLINISNKHRSKDIIPLNEAISKLESELIVKAFEKKGNVRDAAKLLEIHPS
                     TFVRKRQKYIEDGFIK"
     CDS             complement(9636..10085)
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MSFYKEESNIFYIYFQIIKKYKDYMEKSLVEFELTPAEIDVLTFL
                     VNNMDKDITASEISLYRGISKGLVSRAVNLLKDKKIIEPKENCEDGRSVYLKVIDEEDN
                     VVKKVKKINEKFKTQLIKDMDIKDLDLFLKVNNKMLNNIKDIEIE"
     CDS             complement(10678..11760)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MRKLGVSIYPDRSSLEENKKYLDLASKYNFTRVFTNLLSVDMNES
                     HSFNDFKEIVKHASNLGMEVIADVSPAVFKTLDIHYTELKFFKDIGLSGIRLDLGFSGK
                     EESIMSFNPYNLKIEVNMSSGTKYIENIMSHIPNKDNIIGCHNFYPHKYTGLSRKHFME
                     TSSIFKKYGLRTAAFVSSSNGNFGPWPVNEGLPTLEEHRMLPIEVQAKDLFNTELIDDV
                     IVSNCYASDEELKSLEEIDKDILTFKVKLIDGLPKIERKIILEEPHFNRGDVSEYMIRS
                     TESRVKYKDYDFQLINPKDIEKGDILIDSSLYTHYSGELQIALKPMKNSGRTSVVGKIV
                     DKEMYLLDYIKPWQKFKFSL"
     CDS             complement(11753..12082)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MDLEMIIINIINYSGEARSLSMEAMQYGKKGDFEKARHNLNEANK
                     NISKSHKSQTELIQSEARGDKQEVSLLLIHAQDHLMNAITIRDMAKEFIDLYEIISEEK
                     GDINA"
     CDS             complement(12232..14247)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tranf_2_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_12"
                     /sec_met_domain="Glyco_tranf_2_3 (E-value: 4.8e-42,
                     bitscore: 137.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAYYIGLTFVILLILISLDDLIWDIYYLFSPKRKKNNTNIISYKE
                     LTDTVPGLLAIVVAAYREEDVLEDVIENLIDTNHYPNAMYHIFLGVYPNDPDTLEIADT
                     LSKKHKNVHRVIHVLDGPSSKADNINNVIKNILEYENKKDIRFKGIVVHDSEDVVHPYE
                     LLVENYLLNFHKAIQMPVFPLQKMPKLGNIFKNMISGTYADEFAENHYSMLVARNATES
                     FVPSAGTGFVLSREIIDCFCDFNIFPVGSLTEDYKLSLLLKQKGFHLYYALEEVERLKG
                     DGKMAREFIATRSIFPSTYSAVVRQKSRWIYGITMQSFKLRDIFKNKNLSFGSKYSLYK
                     DWKAKFGNILIIPGYSIFIYFILSLFLDIPIIYPKFSLSWYLMLFVTIMMIERQILRGR
                     AVKNVYGYKSTLISILFPPILPFRMVIGNIINFHATLRAWKMHLFKPSTKKRKKKPSWN
                     KTSHEFLEKKVLKTFRRNLGDVLLYKNLISPDELKKSLKKSETNGMRLGETLITEGLVS
                     EEDVIISLCKVNKDIYFKIKPNMVSKEGIEFFGKDFLLQNLIAPIMKTRNTAVFAISNP
                     DDKERIINLLKDKKFEKEVIKFIYSTKEHITNSLEKMDEEYSDQIKFIEKLIEEDILLL
                     DEGIIALRYQNTKKNINETLYDMGFKEQGDRGLVFN"
     CDS             complement(14540..15808)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_13"
                     /sec_met_domain="PTS_EIIC (E-value: 9.5e-58, bitscore:
                     188.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKFMDFMERKFVPVAAKIGGQRHLVAIRDGFASIMPLILAGSMS
                     VLLKNTIFEWITPLQGLIPICDQVWWGSLAIMTLLVVFSVGYNLAKSYEVDPLAAGLIA
                     VGAYFATLPQSHGEAGWGYIHWGYLQATGLFTGLIVALIATEIFVKLIKRDLTIKMPEE
                     VPPAVGRAFAAVIPGTLTMLTFGIVFFIIDKLGGVSLYDVIQESIQKPLEGLSQGVGSA
                     MLAAMLINLFWFFGLHGANILDPVMNALYLPALTANEQAIAAGLEAPNVITRVFFDTYV
                     HLGGSGATLALIIAIFIASKNRKEYREVAKLSAPSGLFQINEPMMFGIPIVLNPILFIP
                     FIITPGILTLIAYIGTATGFAPPTYLVIPWTTPPIIGAFLATGATSASWRAAVLAAINL
                     IVAVLIYLPFVKLADRRREKQTE"
     CDS             complement(15832..16143)
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MLNIMLVCSAGMSTSLLVNKMNKVAKEKRLDVNVVAVAEADVKSN
                     MDKVDVMLLGPQVRYLLPNMKEIMKPKGVPVEVVNTVDYGTMNGEKVLEYALSLAKEV"
ORIGIN
        1 cccaccgcct ctaaatttaa gttttcagta tttggagttc ttcctataga taaaagtgta
       61 tattcactaa taacaaactc ctcttttcct ttaaattcat aatgaactgt attttcattt
      121 acagatttta ctcttgcgtt atttatgatt ttaactccag acttttctaa atttctcttt
      181 aatatattag agatttcttc atcaaccata ggtaatattc tatccatcaa ttccaaaact
      241 gttacttttg ttcctaattt agagaatata tatgcaaatt ctatacctat aactcctcca
      301 cctattatag atatactttt tggtattttt tcaagttcta aagcttcttt acttgttata
      361 atattggttt ctccaattct ctctataaat cttgcttcag ctgttttaga ccctgtagca
      421 attattatat tttcagaagt tatttcttta ccattaacta ttactgtatt tttatcttta
      481 aaacttgctt ctccattaaa tatttctact ccattggatt ctaatagact ttctgttcct
      541 ccaactaatt gttttctaac catctctttt cttttttgaa gtttttccat agataccttt
      601 acatttttag tatctaagcc ttcaattgca aattcactag atctttttat ttcttctaaa
      661 acatttatag tttttattaa agtttttgtt ggaatacatc cttcatttaa acaaactcca
      721 ccaaaatttt ctttttctat aacacaggtt ttcttccctc tttgtgctga tttaatagcg
      781 gtagcgtatc ctcctggacc gccacctatt acagttactt caaaatccat ttttttaccc
      841 cctattacat taaaatttta ataggatttt ctaaaatttc tctaacatat cctaagaact
      901 ctgctgctaa taatccatct ataattctgt gatctactga aagctgtata ttcatcattg
      961 gtcttattaa aatgacatct tctccatctt cattagtttt tacaacaggt tttttattaa
     1021 ttgaacttac tgctaaaatt gctaattctg gtggatttat tatcgctgta aaactatcta
     1081 ttccgaacat tcctaaatta gatatagtaa aagtcccacc gttatattct tcacttaata
     1141 gttttcctac tctagctcta gaaattaaat cttttgtttc ttttgctaca tcttgaatag
     1201 ttttttcttg tatattttta actactggaa caactaatcc attattacct gcaactgcta
     1261 tacctatatt tatactttca tactgttcaa ttacatctcc tactaatgat gcatttattt
     1321 ctggatattt cttaagagct ttacctaaag catagactag taaatctgtt gaagaaattt
     1381 ttaaatcaga gttttcattc aattcttttc taaatttagt taaatttgta gtatctacat
     1441 cattactaaa gtacaaatgt ggagctgtaa atttactttc agataaccta tctcctatta
     1501 tttttctaac acctgaatat gggatagtat ctttaactct cttagtatgg tcttcttgta
     1561 atatattgga ttttctttga acatcatctt taacgatttt tcctcctact ccagttcctt
     1621 ctactgtaga tatatctaat cctaatttat gtgctaattt tttagcaata ggtgatactt
     1681 taatatcttt ttcagttatt ccacctctaa atcctgttcc ttctatattt tttatactat
     1741 ttatatctaa actattttct ttaacatatc ttctagctct tggagtcagt tttaaatctg
     1801 tgtctattac aacttcttct atattttcag tttcttcaac aatttcttct tctccacttt
     1861 cttcatcagt ttctattcca ttttcttcat tatactttct aagtatttca tctggatttt
     1921 ctccactttc tcctattatt gcaataggag taaatactgg catttcttct ccttcttcta
     1981 ctagaagtct aagtactatc ccatctgtta ctgcttcaac ttccatcgtt gttttatctg
     2041 tatgtatctc aaatagtact tcccctgaag atacactatc gccttcactt ttatgccatt
     2101 ttactaactt accttcatcc atattaaagc ctagtttagg cattataact acttctgaca
     2161 tgattattcc tcctcaataa acttatatca tttctcttat tgctttttct atatcttttt
     2221 catctggtat tagtgggaat tctaaagctg gactaaatgg taacggaaca tctgctgtac
     2281 ctaatctctt aactggtgca tctaaagaat agaatatgtc gtccataatt ttcattgtta
     2341 tttctccact tattccataa cttttgtgcc cttcatctat tatcagtaat tttcctgttt
     2401 tttctactga ttttattatt gtttctttgt caaaaggtac taaagttctt ggatctatta
     2461 attctacatt tattccttct tgttttaatt ttttaacaac tttttctgtt ttaactaaca
     2521 tcatagaagt agctacaatt gttatatcat caccttcatt aacaattctt gcctgtccaa
     2581 atggaattgt atagtcttca tctgaagtta aatcaaattt ttctgtataa agcattttat
     2641 gttcaaagaa taatactggg ttattatctc ttattgcagt ttttaaaagt ccttttgctt
     2701 ctgctgcagt agatggaact accactttaa gtcctggaca atgtgccgcc caagcataaa
     2761 atgattgaga gtgttgagct gctgatgatc tacctccacc tattggcatt cttattacca
     2821 tcggtactct gacttgtcca ccagacatat atgttatttt tgcagcttgg ttacaaattt
     2881 gatccattgc taccatcata aaatcaccaa acattaattc tacaacgggt ctcaaccctg
     2941 ttatagctgc tcctatacct agtcctacaa atcctgattc agatattggt gtatctttaa
     3001 ctcttagatc tccatatttt tctaataatc cagcagtaca tttaaagtta ccacctattg
     3061 tacctacgtc ttctcccatt acaaaaacat tttcatctct tgccatttct tcatctaatg
     3121 cttctaaaat tgcatctcta tacattatgt ttctcatgaa attccctcct agttattttt
     3181 aaactaaata caaattttaa ttaatctaca aaaacatctg tatatgcttc ttctatttct
     3241 gcatatggac tatcttcagc aaatttaact gcttctttta tttcattttc cactttttct
     3301 tctatttcat ttatttctct ttcatctatt aattctaact tcaataagtt tttgataggg
     3361 tctttagctt tccaagtctc taattctttt ttatctctat aagttgctgg gtctccaacg
     3421 tgatgtcctt gccatctata tgtcttacat tctattaaag taggtcctcc gccttttcta
     3481 gctttttcaa cagctttaga tacggtttca taaacctcaa aaacatcatt tccatttatt
     3541 gtaactcctt ctattccgta tcctactgat ctttttgata attggtgttc ctttgtaact
     3601 tttctgatgt ctacagatat gccaaaacag ttattttcaa taatatatat tattggcaaa
     3661 tcccaagctg atgccatatt aatactttca tggaaagttc cttgatttga tgcagaatct
     3721 ccaaagaatg ctattgtaac ttctcctgat tctttatatt tagatttgta tgcagcacct
     3781 gtggcaattg ggattcctcc gccaacaata ccatttgctc ctaaaatgcc tttatctaaa
     3841 gccattatat gcatggagcc accttttcct ttagaatatc catctttttt acctagaatt
     3901 tcagccatca ttttattaag atcagcacct cttccaacta ggtggccatg acctctgtga
     3961 gtacttgcta tataatcatt tttatcaaga gctgcacatg cacctgttgc aatagcttct
     4021 tcccctaaat ataagtgtgc taaacctggc atcatacctt ttttataaaa ttcaaatact
     4081 tcttcttcaa atcttctcat tctatacata acttcataaa acttttttgc taataccttt
     4141 ttattgtctt ccattacttc tcctcctagc tattttttat attatattta tttaaataag
     4201 cttctctaag ctcttgccta aaatcaggat gagcaatttc tattaatgct tctgctcttt
     4261 gtcttaaatt cttacctttc aatcttgcta ttccatattc tgtaactata taatctacat
     4321 catttctaga tgttgttacc gctgctcctt tatctataac aggcactatt tttgagactt
     4381 tccctttaac tgtagatgac attgctataa ttgatttccc atttttgctc atgctagcac
     4441 ctcttacaaa atctacttgt ccgcctactc cacttatttg catacttcct atactatctg
     4501 aaactacttg tcccattaaa tcaacttgta cacaagagtt aatacaaaca atattatcgt
     4561 ttttcattat ttccactgga ttgtttacaa aatctgcact tctcatttct accattgggt
     4621 tattattaac aaaatcgtat aattttttag ttcccattaa aaatgtagct accattttat
     4681 ttttaaaata tgttttctta ctattgttta taacgccagc atttacaaga tctactactc
     4741 catcggaaaa catttctgaa tgaattccta aatctttttt atcatataaa caagacaata
     4801 ctgcatctgg aattcctcct attccaagtt gaagtgtatc accatcattt attagactcg
     4861 cacaatgtct tccaatttct ttttctatct ttccgatttt tggaggaata agttctataa
     4921 tcggctcatc tttttcaacg ataaaatcca tttctgatac atgtataaaa cagtcaccta
     4981 aagtcctagg catatgttta tttacttgta ctattactaa tttagccctt ttacatgctt
     5041 ctttagtata atctacagat acaccaaaac tacaatatcc atgttcatct ggtgaactta
     5101 cttgtataag ggctacatct acaggaagta actctctaaa aagacttggt atttctgaga
     5161 agaatacagg tatgtaatct gctctacctt cttttaccgc ttctcttgtt gtacttccta
     5221 caaatagaga attatgtcta aaatgtttct ccattccttt ttctacatat ttagattttc
     5281 ccattgctac catatgaaca atttcaacat cttcataaca atccttattt tctaccatag
     5341 catcaataag ggtttggggt tctcctacag catgtcctac aactactcta tctccagatt
     5401 ttatttggtt tactgcttcc tctggagtta ccaatttact atcataaatt tttctccatt
     5461 ccatatattt caactccata tatttcatct aatttatctt taatattttc ttagcaaaac
     5521 taattaaatc ttcatctact gaactatcta actttatatt tccaatttca ctacctaaat
     5581 tttctcttaa aatcctttcc actatatctt ccgtagtcat ttgggcagaa ggacaattct
     5641 tacagttccc tgtaagtctt ataactaatt ctttatctac aagagatttt atttctatat
     5701 cacctccatg tagccttaac tttggtctaa tatctttttc tattattttt tctattttat
     5761 atctaagttc catgatgtcc tcctgctatt ttaaatttaa tttgggttat attcttagtt
     5821 tatttatctt tactgtaatc taccttagca attattcttg ccatttcttt cttatcttct
     5881 agttttcctt gtcttgatat cattattctt tgggcttgcg gtgagcctgc accgtgtaaa
     5941 gattcagttc tatatcctac agctgcagtt cctaaggtaa tgttttcaat aagtcttaaa
     6001 attctaagtc tattttctgt agatgttcct gttttccccg caaaatattt ttctacatat
     6061 tctcctattt taggatcttt aaaatcttgt tctgatggca ttgtaaccat taatccacct
     6121 gctatatctt cagcaagtct tgctatttca tatgggaatc ttgtgacatt ttgttttgag
     6181 acgtttgcaa gtaaaagatc tattaaatag tttcctgatt ccgtttcaat tccttcatag
     6241 gaacaggcta acgctccagc ccacagagtt tcatttaagt gtatcatttc tattaattta
     6301 tcttttatat gactagcttt tggaacccca ttatagtctg cagctaaagc agtagctcct
     6361 attaacacat ctcctacacc tgttttacag gcatatgatt gtctgtgata tcctgcaaat
     6421 ctttccacca tcatccctgc aaaatcatat tctttgcaca taaatactct ttcatttggc
     6481 acaaatacat tgtcaaatac tactaatgct tcatgtccac caaattctgc atttcctagg
     6541 tccatatctg ctccatcttc taattttcta gtatcacaag attggcgacc ataaatcata
     6601 aatacacctt ctgcatcaga tggtactgca aaagatactg cataatcttt atctttttct
     6661 tttaaagcca tagttggcat tattaattgt tcgtgagaat taactgctcc tgtttgatgt
     6721 gcttttgcac cttttactat tattccatct tctctaactt cgacaactct taagtatagg
     6781 tctgggtctt cttgttcaga tggtgaaagt cctctatctc cttttggatc agtcattgct
     6841 ccatctactg tcaaatcatt tttttgtaca tattttaaat attccttaaa tctttcaaaa
     6901 taatctgttc catatttttt atctatttca tatgtagtag aatagatagc attaaaagca
     6961 tctaatccta cacatctctg aaaacatgac gcagtttttt gtcccatcaa tctttgcatc
     7021 tttacttttt taactagatc ttctgtactt tgatgaatat gacaaaatct gtttattggt
     7081 tctcctgtta aatgagatat agctgtcatt aaatctttat actcatcttg gtttgcaagt
     7141 tcataagtca ttgcaactga attcatagaa ggtcttatta ttggatggtc aactggattt
     7201 tctattaact ctccaaacat ataaaccttt aagtctaatt ttcttaaact ttcaatatac
     7261 tcttctctag ttttaattga catattaata acactccttt tttttattac accttttata
     7321 attgcagata acgtgccaaa tactatttat ttttcaaaaa catttttaga ggtgtaattt
     7381 taaacaaaaa ttcgcattat ttttaaaaaa caataattat tattttaaaa taattgtgtt
     7441 ttttgttgca tttttgcata atattaattg catttggtca tttatttagg ttttaagcta
     7501 atttaaaaga aaatatgcat tactgcaaca ttgttgcagt aatgcatatg ctttaaaatg
     7561 cttttattta aagttatttt atgaaaccat cttcaatgta tttttgtctt tttctaacaa
     7621 aagttgatgg atgtatctcc aatagtttag cagcatctct gacatttcct tttttttcaa
     7681 aagctttaac tataagctct gattctaatt ttgatatagc ttcatttaat ggtattatat
     7741 cctttgatct atgtttattt gaaatgttaa ttaacatact ttgtggtaaa tcctctttag
     7801 taatagtatt attttttgca aatacaaaaa gtctctctat taaatttttt agttctctaa
     7861 catttcccgg ccaatcataa taatacattg tatgaaacgc ctcactatct atatctacat
     7921 ctatattata tttttcattt atttccctta aaaattcttt agtaagagct gttatatctt
     7981 ctcttctatc tcttaacggt ggaatatgta ttggaactac atttattcta taatataaat
     8041 cctctctaaa ttttccagct tcaatcatag aattcaaatc tctattagtt gcagtgataa
     8101 ttctaacatc tatatctatt tcagaatcag atcctatttt tcttattttc ttatcctgta
     8161 gaacagttaa aagtttagac tgcatactaa gaggtaattc tcctatttca tctaaaaata
     8221 aagttccacc gtgtgcttgt tcaaatatgc ctatttttcc agaatctcta gctcctgtaa
     8281 atgctccctt ttcataacca aaaagttccg attcaattaa actagcagga atagatgcac
     8341 aattaagttg tatgaatttc ttgtcacttc tattgctatt tttatgaata tactctgcca
     8401 tagcaccttt cccagttccc gtttctcccg ttattaaaat tgtactatca tattttgcca
     8461 ccttctttga ttgttctaat attatttctg tctcatgtga cttgtacatg aaattcatag
     8521 ctctctcctt ctgagatttt agtttttgaa tctccctttc tctttctatt attttttctc
     8581 gtaaattcat aatttctgtt atatctctta ctatagttac tacatattca agttcatctt
     8641 tatcatttat tattggagta ctagttatta acgctatttt attattagct aatttttgtt
     8701 gaatgcttat agattttcta tttttaatag ccaacaatgt accagattca tctattaatt
     8761 tttcatctaa cacttgatat atagttttac ctataaaatg ttctcttgaa ttatcactta
     8821 atttttcata tgcagtattt acatataaag ttttagtatt gcagtctgtc atatatacac
     8881 cttctgccaa atgatcaaat aatgttttaa atttataaag ttctctatct ctacttttaa
     8941 gtatttttaa aatatcttca cgggataaat tttcgtaagt acttaagtta tttttcatcc
     9001 atatcctcct cttttttgct ttagaaaata aattaaataa tttagtagat gtatttttta
     9061 taataccatt tatagaaaat tctttctatg aaacttatca tataattttt tgtaaaatag
     9121 tataattata ggtaaaaata aaagtttaat taaagataac tttgaattta aattaaatat
     9181 aaataaagaa aattagaaaa gtaattagat cctaaataaa ataggaggta tattttaaaa
     9241 tactcaaaaa tatagacatg ataaaaaaac taaaaaaagt cctaaaacct tcgtttatga
     9301 aagttgtaga acttttgttt attcctacca ttttagtact aaatagaatt gtattactaa
     9361 tttatcttcg atactataac taataatagt tattatttta aaaaaccata tcacaatata
     9421 agatttgatc ttatctcctt ttttataaat aaatatttaa aacattcttt tgaatttata
     9481 aaatagttcc tatcatagat aaatgctata agttgtatat attatagagt aaacttatta
     9541 actgacctat aatagttagt attgctaatg aaaataataa actttttaca ttctctgttt
     9601 ctaatctttt tctctgccat ttctaaaata tctccttatt ctatttctat atcctttata
     9661 ttgtttaaca ttttattatt tacttttaaa aataaatcca aatccttaat atccatatct
     9721 ttaatcaatt gtgttttaaa tttttcattt atctttttta cttttttaac tacattatct
     9781 tcttcatcta tgactttaag atatactgat ctaccatctt cgcaattctc ttttggctca
     9841 attattttct tatctttaag caaattaaca gcacgtgata ccaatccttt tgatattcct
     9901 ctatacaaac taatctcact tgctgtaata tctttatcca tattattaac taaaaatgtt
     9961 aatacatcta tttctgctgg tgttaattca aattctacta atgacttttc catataatct
    10021 ttatattttt ttattatttg aaaataaata taaaaaatat tagattcttc tttgtaaaat
    10081 gacattttat ctccctcttt caatatagtt tacttttaaa ctacatctat tagtatatat
    10141 tatttttagt tcaaaaatca actaaaataa aaaattaacc agacaccttt ctatctaaaa
    10201 gaatttggta taagactttt gcatcaaatt ataagttttt aaatatcaga ttattattct
    10261 gctaattgaa ctaaaactag ttaccaatat tttaaagaaa accttagatt tgatcagtat
    10321 catgttagga gtcatttatc cattgaaaga tactttttac tgtgctttaa aaagtatata
    10381 tgattcgctg aaattattag cttagattta aaaatcttaa aaaatacaat atgatactta
    10441 tatacttctt tacgggaatc atcatgtaac taaatattag ttatcctacc atggaaattt
    10501 aaatttgaat tttgcataac tagagttatt aaaaatccaa aaagcttcat tggacatatt
    10561 taaaatatag tcctacaata cttattgctt atatagctaa tagcttacta ccattaaaac
    10621 ttaaaaatgc atgtcctttg aaggactatg catttttaat atattttatc ctatacatca
    10681 caaagaaaat ttaaattttt gccaaggttt aatataatct aacagataca tttctttatc
    10741 tacaatctta cccactacac tagttctacc actatttttc ataggcttta atgctatttg
    10801 caattctcca gaataatgag tatataagct actatcaatt agtatatctc ccttttctat
    10861 gtccttagga tttattagtt gaaaatcata gtctttatat ttcaccctac tttcagttga
    10921 ccttatcata tattctgaaa catcacctct gttgaaatgt ggttcttcta atataatctt
    10981 tctttctatt tttggtaatc catctattag tttcacttta aaagttaaaa tatccttatc
    11041 tatttcttca agggatttta attcctcatc agaggcataa caattagaca caattacatc
    11101 atctataagc tcagtattga acaaatcctt agcttgaact tcaataggga gcattctatg
    11161 ttcttctaat gttggtaaac cttcgtttac aggccaaggt ccaaaatttc cattagaaga
    11221 tgaaacaaaa gcagcagttc ttagaccata ttttttaaag atactagaag tctccatgaa
    11281 gtgttttctg gacaatccag tatatttatg gggataaaaa ttatgacatc ctatgatatt
    11341 atccttattt ggaatatgac tcattatatt ttctatatat ttagttccac tgctcatatt
    11401 tacctctatt ttcaaattat aaggattaaa gctcataatg ctttcttctt ttccactaaa
    11461 tcccaaatcc aacctaatac cagagagacc tatatcttta aaaaacttta attcagtata
    11521 gtgaatatct aaagttttaa atactgcagg ggaaacatca gctattactt ccatacctaa
    11581 attagatgca tgttttacaa tctccttaaa atcattaaaa gaatgacttt cattcatatc
    11641 aacagataat aaatttgtaa aaactctagt aaagttatac tttgatgcca aatccaagta
    11701 ttttttgttc tcttctaaag atgatctatc tggataaatt gatactccta atttacgcat
    11761 ttatatcacc tttttcctct gagataattt catataagtc aataaattct ttagccatat
    11821 ccctaatagt tatagcattc attaaatgat cttgagcatg aataagtaat aaagatactt
    11881 cttgtttatc tcctctagcc tctgattgaa tcaattccgt ttgactttta tgggatttag
    11941 aaatattttt atttgcctca tttaagttat gtcttgcttt ctcaaaatct ccttttttcc
    12001 catattgcat agcttccata cttaagctcc tagcctcacc actataattt ataatattga
    12061 ttattatcat ctctaaatcc atatcactct ctccttcaat aaattagatg tttccatcct
    12121 attattatat tctgtacttt ttttaccaaa ttaaattaat attattatct ttattataaa
    12181 gattgaattg ttggctccct cattctaaag catatcaaat atattttcct atcaattaaa
    12241 tactagacct ctatcccctt gttctttaaa tcccatatca tatagtgttt cattaatatt
    12301 cttttttgta ttctgatacc ttaaagctat aattccttca tctaggagca aaatatcttc
    12361 ttctattaat ttttctataa attttatttg atctgaatat tcctcatcca ttttttctaa
    12421 agaatttgtt atatgctctt ttgtagaata tataaacttg ataacctctt tttcaaattt
    12481 tttatccttt aataaattta ttattctttc tttatcatca ggatttgaaa tagcaaatac
    12541 tgctgtattt cttgttttca taataggtgc tataaggttt tgtaatagaa aatcttttcc
    12601 aaagaactct atgccctctt ttgaaaccat attaggttta attttaaaat aaatatcttt
    12661 atttacttta cataaagata taattacatc ctcttccgat actaaacctt ctgttattaa
    12721 agtttctcca agccgcattc cattagtttc tgatttttta agagattttt ttaattcatc
    12781 tggtgatatt aggtttttat ataaaaggac atctcctaaa tttcttctaa aggtctttaa
    12841 gacttttttt tctaaaaatt catgactggt tttattccaa ctaggctttt tctttctttt
    12901 tttagtgcta ggtttaaaaa gatgcatctt ccaagctctt aaagtagcat gaaagtttat
    12961 gatattccca ataaccatcc taaagggcaa tataggtggg aacaatatac ttataagggt
    13021 acttttatat ccatatacgt tttttacagc tcttcccctt aaaatttgtc tttctatcat
    13081 cataatagtt acaaataaca tgagatacca tgacaaacta aatttaggat aaattattgg
    13141 aatatctaaa aacaaagaaa gtataaaata tataaaaatt gaataacctg gtataatcaa
    13201 tatatttcca aacttcgctt tccagtcttt atacaaacta tatttagaac caaatgataa
    13261 atttttattt ttaaatatat ctctaagttt aaaagactgc atcgttatcc catatatcca
    13321 cctagacttt tgccttacaa cagcactata agttgatgga aatatacttc tagtagctat
    13381 aaattccctt gccatttttc catctccttt aagtctttct acttcttcta atgcgtaata
    13441 aagatgaaat cccttctgtt taagcaatag tgaaagctta taatcttctg ttaaactccc
    13501 tactggaaat atattgaagt cacagaaaca atctattatt tccctagaaa gcacaaaacc
    13561 tgtacctgct gaaggtacaa aagattcagt agcatttctg gccacaagca tactataatg
    13621 attttctgca aattcgtctg catatgttcc agatatcatg tttttgaaaa tatttcctaa
    13681 cttaggcatt ttttgtagtg gaaatacagg catttggata gccttatgaa aattcaaaag
    13741 ataattctca accaataatt cataaggatg aactacatct tctgaatcat gtactacaat
    13801 acccttaaat ctaatatctt ttttattttc atattctaaa atatttttta ttacattatt
    13861 tatattatca gctttagagc taggtccatc tagcacatga ataactctat gaacattttt
    13921 atgcttttta gatagagtat ctgctatctc taaagtatca gggtcgtttg gatatacacc
    13981 cagaaaaata tgatacattg catttggata atggtttgta tctattaaat tttctataac
    14041 atcttctaat acatcctctt cacgatatgc tgctactaca atggcaagta gaccagggac
    14101 cgtatctgtt agttctttat aagatatgat attagtatta ttctttttcc tctttggact
    14161 gaaaagataa tatatatccc atataagatc atctaaactt attaaaataa gaagaataac
    14221 aaatgtaaga ccaatgtaat aagccacttt atcatcccct tttgatataa caaatataaa
    14281 taatcaaata tattataaaa gtcaatcaag acaatagacc ttttaattct tccatatgag
    14341 ttatcttata aagtattttg cttactttaa aaatgtatag attcatttat agaaacgaga
    14401 aaataattaa taaatagttt tatataaaac attggtaaga agtagagata accctaatta
    14461 acctatactt ttcctatttt tttctctact tcttacatag atgtttctaa atccctttag
    14521 cgttagaaag gattattcac tattcagttt gtttttctct ccgcctatca gctaatttaa
    14581 caaatggtaa atatattaat actgctacta ttaaatttat agctgctaat acagctgctc
    14641 tccaacttgc tgatgtagct cccgttgcta gaaatgctcc tataatagga ggtgtagtcc
    14701 aaggtataac caaataagta ggaggtgcaa aaccagttgc tgttcctata tacgctatta
    14761 aagtcagtat tccaggcgta attataaatg gaataaataa tattggatta agaactatag
    14821 gaattccaaa catcataggt tcattaattt ggaataaccc tgatggtgca gataatttag
    14881 ccacttctct atattctttt ctgtttttag aagcaataaa tatagcaatt attaaagcta
    14941 atgtggctcc cgaaccacct agatggacat aggtatcgaa gaaaactcta gttattacat
    15001 ttggtgcctc taatcctgct gcaattgctt gttcattagc agtaagagca ggtagatata
    15061 atgcattcat tacagggtct aatatattag caccatgtaa tccaaagaac caaaataagt
    15121 taatcagcat agcagctaac attgcagatc caactccctg gcttaaaccc tctaatggtt
    15181 tttgtataga ttcttgtatt acatcatata aacttactcc tcccaattta tctattataa
    15241 aaaatacgat accaaaagta agcatagtaa gtgtacctgg tataactgct gcaaaagccc
    15301 ttcccactgc tggaggaact tcttctggca ttttaattgt taaatctctc tttattaatt
    15361 tcacgaatat ttctgtagca attaatgcta ctattaatcc tgtaaacaac cctgtagcct
    15421 gtaaataacc ccagtgaata tatccccagc cagcctctcc atgagattga ggtaatgtag
    15481 caaaataagc tccaacagca ataagtcccg ctgctaatgg atctacctca taagatttcg
    15541 ccaaattata gcctacagaa aatacaacta ataaagtcat tattgccaat gatccccacc
    15601 atacctgatc acatatagga attaatcctt gtaatggagt aatccattca aatatagtat
    15661 tttttaataa aactgacata gagcctgcaa gtattaaggg cataatactt gcaaatccat
    15721 cacggattgc aactaaatgt ctctgtcctc caatctttgc tgctaccgga acaaactttc
    15781 tctccataaa atccataaac ttttccatac taatccccct tactagtatt tttatacttc
    15841 tttagccaaa cttaaagcat attccagaac cttctcccca ttcatagttc cataatctac
    15901 agtatttacc acttctactg gtactccttt tggtttcatt atctccttca tgtttggtaa
    15961 cagatacctg acttgtggac ctaacaacat aacatctacc ttatccatat tactttttac
    16021 atctgcttct gctacagcta ctacatttac atctagcctt ttttcttttg ctactttatt
    16081 cattttattc accaataggc tagtagacat tcctgctgaa cagaccaaca taatgtttaa
    16141 cataattatc agtcctttcc atataatcta ttatatttct ctactccatc acctcctgta
    16201 tccccctcgc gctatattac aattgcaatt accttgccaa atgtttctat gttcaaaaat
    16261 aaaataaatt aaattatgtt atgatagttc atggatttga ggactaaatt gtatttcgaa
    16321 tttagtgtgt aaaaaaataa attagtgtgt agatgactac acactaatgc acactgattt
    16381 gattggataa gaatgatttt aatatatatc ctatctcatc ttctcctata acaatttcat
    16441 atttattttc tataggagaa aatatttctt tcaaaatctt catatccttc ttatatattt
    16501 tcttgtattc ttctaaatca tcaaatttcc gtggtattac tccttttatc aaattatcta
    16561 ttaaaaaaca tatatggagt actatgccca ttcttacatc tatggatact tttagtccta
    16621 atttatattc tatttcatat aaaatatatc taatttcttt tacgattttc tcacccttta
    16681 catttgataa atgttctgtt aaagattgtg aaatttttag gcacatgtca ttttcttcaa
    16741 aaatattatt taatttatct attccttcat ttgtaaatat atctacagca agaaatactg
    16801 gcgtccaaga tatatctaat gatatagtag atattattgc caatatatta tatttatctt
    16861 tcaatttgtg caatctattt tctaagttat tttcatctat tatatttatg gtaaatatat
    16921 ctatgttttt attagatatt tcttttccaa taatatttgc aatctttttt gaagcaccat
    16981 ctcctgtaaa acaagcagta acaataatat catttatatt gttgtcttct tccaatatat
    17041 tacccctata tttatataca tgtttatttt taaaggcctc cattatttca tctatactat
    17101 atcctactat tgattttctt aaaacctcca aaaccatagg cgtactgacc atttcaatag
    17161 ttcttacttc tatgccagtt tcttcccaaa tcatatctcc aaaagtagtc aaagaaccca
    17221 tatccactaa aataatcaca ccttctccct tatttatttc ctccaccttt cttttagcta
    17281 tga
//
