LOCUS       c00248_NZ_CABK..       13669 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTV010000248.1 Actinomyces polynesiensis isolate
            MGYG-HGUT-01480, whole genome shotgun sequence.
ACCESSION   c00248_NZ_CABK..
VERSION     c00248_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:52:02
            Original ID  :: NZ_CABKTV010000248.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13669
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..84
                     /locus_tag="ctg248_1"
                     /transl_table=11
                     /translation="SGGSASGADTSPERDAAEDSTAGGGEG"
     protocluster    1..13669
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9301:13472]"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9302..13472
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
     cand_cluster    1..13669
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /kind="single"
                     /product="Respiratory_glycerol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13669
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Respiratory_glycerol"
                     /region_number="1"
                     /rules="(DAO and Fer2_BFD and FAD_binding_2 and Fer4_8)"
                     /tool="gutsmash"
     CDS             81..2258
                     /locus_tag="ctg248_2"
                     /transl_table=11
                     /translation="MRGIWMLVRRDVARATSNTMAIIVVVGLSVLPSLFTWFNVIASWD
                     PFANVDELTVAVANTDEGYQSDLIPVRLNIGDQVVSDLRANEDFHWVVTTEEDAVDGTK
                     SGEYYAAIVLPPEFSKDMLTFYAPGATRTDITYYTNEKKNALAPKITGQGADRVSAGIN
                     RVFSQTLSEIGVNILSSLSDHLSSDQTKVLLARLESHVGQTSAQLRSAATTADTFSTLI
                     ASSRTLLGSSTRLVEATGQTLDDATGAIGSGLDAAGSLKSTLDSATAGVSAALEVSSQG
                     WADLADKVDAVFAAADQQTTDGVDVLNGMSEQVQAQIDAYEGLRTRLEQDVAPNLPDGA
                     LDPALDALDLAISHQEDVQDALDQAAGKLSSENSGAQATHRELARTIAEAKAAVDKLHD
                     VYDTDLRGQLDQLGVALAAARSAAGDVGTDLDRAASGLTGASDSLAVQLAHAQTVTTSV
                     STDLDAAAETFDRLGTALAEAADTGDLSALQGVLGEDPSSVAASLAAPVGLNRVAVFPV
                     ANFGSAMAPLYTMLALWVGALLMSVSIQVGVHRDTLPDGPDLAPHQKYLGRYGIFGLIG
                     FVQSTLVCLGNLVFVQVQSVHPLLYMLTGWMTSLVFTLTVYTAVVAFGNAGKALCVLLL
                     VVQISTSGGAYPLQLLPEWFQRISIFLPATYSVRAFTAAIAGIYHADYWHSIGTLALFI
                     LPALLLGLVVRKPLISFNRNLAAALESTKLM"
     CDS             2450..3673
                     /locus_tag="ctg248_3"
                     /transl_table=11
                     /translation="VSAGFHDHDPSEAGLRRIASAAQRSGALLTEVRADTTSPDPALED
                     RPVGTFSVFDGLANLGAGQMVPAGLITGVTVRPTHKRRGLLRAMMTLNLAQLAARDVPL
                     ALLTASNAQLYGRYGFQTVVRESRVTVSPGPGFSLRTPTTGRVEVVTMGWLLPRMPQVF
                     DRYHRRMRGSTTRYEGYYEDLYHDPKADRVDGKFVAAVHIDDTDNLDGYVTFEIEGSPA
                     LKVRELVAATPAAELALWDHLNRVELIKEIVAPTVPEDSLLPLALVDQRSMRTTSVSDA
                     LWARVLDPVQVLDARPYTVAARGAHLQVAFAVEDELGHASGAYRVVTAPEGVQVTRLAG
                     PESAPAGPDIPTPVRLTVQALSALAFGSATASDLAGAQMISGAGEGELEVMDALFAPVG
                     RAGFMSHF"
     CDS             complement(3716..5161)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg248_4"
                     /sec_met_domain="Lyase_1 (E-value: 3.3e-104, bitscore:
                     338.0, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.3e-18, bitscore:
                     55.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTRTEEDLLGRREVPADAYYGVHTVRAVENFRISGHTISGEPEL
                     VRGMVMVKKAAALANKELGVLPFDVADAIVAACDEILEHGRCMDQFPVDVFQGGAGTSV
                     NMNTNEVVANLALELAGFDKGRYDVIHPNDDVNKSQSTNDAYPTGFRLAVDVRIDALID
                     EVRALVTAFHAKGEEFEGVLKMGRTQLQDAVPMSLGQEFHGWATNMEEEVTRLHNAQGL
                     LLEVNLGATAIGTRLNTPDGYAHVACEKLAEVSGLPIRSAEDLVEATSDNGAYIAAHSA
                     VKRVAMKVSKICNDLRLLSSGPRAGLKEINLPEMQAGSSIMPAKVNPVIPEVVNQVCFK
                     VMGNDVTVTAAAEAGQLQLNVMEPGLAQAMFESLNLLTNAVATLREKCVVGITANEQRC
                     REYVMNSIGIVTLFNDIIGHHMGDSVGKEAARTGKSVRAVLLERHLLTEEQIDAILTPE
                     NLLHPRYTGRRYGPEDRGLPARG"
     CDS             complement(5454..6350)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg248_5"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-25, bitscore:
                     79.7, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRHTTQLPLAGHTALVTGVSRRRGIGHAVAAALLDMGASVFVHH
                     FARHDHDQRWGADDLDALLEGLGERVAPGARLGEADADLSDAGTVEPLLSAARSLTGSL
                     DILVCNHALSGHDGSILDMDAARLDAHWDTNSRSTLLLTAGFARGLAGGRQCPALPGER
                     TPRPDAGAGAGAARVPLGKVFWMTSGQVHSPMRGEVAYAASKAALAGVTRTVAAELLDL
                     GIVLNTIDPGPVNTGYLDPATTDRGAEQVAELLAATPFGRFGDPSDPAHLIAWLASDEG
                     SWVVGQVLTSDGGFSTV"
     CDS             complement(6361..8301)
                     /locus_tag="ctg248_6"
                     /transl_table=11
                     /translation="VDAADAEVTSVALVVVLAVLAIVLVHRLAPKVGVATPLLLVLLGV
                     GVSFVPAVPAITVEPEWILAGVLPPLLYATAVSLPSMDFRRDFTAIGGLSVFLVLISSL
                     VLGVVFAAVIPGISLSIGIALGAILSPTDAVATSIVRRLGVSPRIVTVLEGESLLNDAT
                     SLVLMRSAIAATAATVPLWQVGGSFLYAVAVAVVFGVAIGKGGLLLRGWLANPVLSTAV
                     SFAVPFLAFLPTEALGASGLVAVATAGLVTGNGAPTHLSPLDRRSEASNWRTVELLLEG
                     AVFLVMGLELFGLVTEVRKEHESLWMALGIATLAVALILVLRALFLVPLLAWLNRRMRR
                     GQELRDAYRELRSHFAPSPTARGDRRGPGARPGVPDPAVPGGRPTTPPRTAAPRGPSLV
                     DLSSLPEPTAWKLKRRFRLAVTQHTAPPRERIARWHRRLSRHSADIDYFTAEPLGAREG
                     TLLVWAGMRGVVTLAAAQSLPAGIPQRALLVLVAFGVAAGTLLVQGSTLPALARALGLA
                     GDTAPPVSDRIALRASLDGAALAALDDPALRRRDGNPYDPGVLHRAHVDVDRMRLSRAE
                     SAATTPDIFAQYRELRLLAIQAQRRALAAARASRSYSSRTLRYALSLLDSEQIEIQARR
                     GPATPSDDEDD"
     CDS             complement(8498..8938)
                     /locus_tag="ctg248_7"
                     /transl_table=11
                     /translation="MVDRLVIPVLRVLLWVLVVLGAGLTVTSLLMETGQDVSYPEMTRA
                     IVFLLFLVPTAAAVLGLVLLRAWRISRRRAASAVGPPGPPPAPSDPSHFDPDTVWSGGV
                     PSGRPTTPPPVLHTPSHPETFAPTPRPTQDDGGAVPADPPTR"
     CDS             9302..10990
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: DAO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer2_BFD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg248_8"
                     /sec_met_domain="DAO (E-value: 3.7e-47, bitscore: 150.9,
                     seeds: 522, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 6.6e-10, bitscore:
                     28.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQVAGARASRPGTSTRAPVLGGIAAAVQDGKEHVVKTIQTDVVVI
                     GGGSTGAGVVRDAAMRGYRTVLVDRADLGQGTTGRFHGLLHSGGRYVVSDPESATECAQ
                     ENAILRRIQAGAVEDTGGMFVTTPVDSEEFADGYVAACRAAKVPVEEISVAEALRREPR
                     LNPGTKRAFAVQDGTVDGWQLVWGAVRSAEAYGAKILTYHRVTAIEHGDGQVRAVVAHD
                     ERAGEDVRIECSFVLNCGGPWAGKIAAMAECHGVDVVPGAGIMIAMNHRLTQSVLNRCI
                     YPADGDILVPVHPVCIIGTTDQKTDDPDHLPIPRAQVQQMFDSGEHMIPGFRHARALHA
                     WAGARPLVRDSRVSASDTRHMARGMHVVDHEERDGVKGLLTIAGGKLTTYRLMAERIVD
                     QMCEQMGEQRECHTADEPVPGSEDHHLYTLGHRLHDVETETKAPGGQQIICECELVTRS
                     MLEKVMDGLGEFTLDDVRRQVRLGMGPCQGGFCASRATGIAHERGDIDAARATGLLRLF
                     MKNRWIGLWPILFGEQVRQCALDNWIYEGTLDLEHLPEPAEEVVR"
     CDS             10987..12234
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 122.5; E-value:
                     8.1e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg248_9"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.3e-38, bitscore:
                     122.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVVVIGAGLAGLAAAVRLQEQGREVALVTKGIGGLQLGQGTVD
                     VLGYTPAPVAEPLAAVDAYRSEHPDHPYGHFPGTEVGDALAWLGSTVGEGLLVGDGQRN
                     FRLPTAVGALRPTALAQPSMVASEPTDGRSYVFVGLRRLKDFYPDLVAANLARQTTPSG
                     EPIRARAVHVDLEVREGEADTSGLNFARALDRPEVRQHLCALVAPLLEDGDTVGFPAVL
                     GVEDTDAWRDIAARLGHDVFEVPLPPPSVPGMRLNERLTRLVKSRSRLIVGSRVLGYEA
                     EDGHVVSVTIKSAGHHRQLRADEFVLATGGFESGALAMDSYGTVTETTFGLPLVGTGGE
                     LVHADYWGTEQPLFRVGVAVDDAMRPLDEDGAPVLDNLHAVGGLLAGATRWREKSGDAI
                     ALVSALRAADSILGSK"
     CDS             12234..13472
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg248_10"
                     /sec_met_domain="Fer4_8 (E-value: 7.9e-14, bitscore: 41.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7e-05, bitscore: 12.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNETILDLESFGLRSSLDACVKCTICETQCPVARVTPLFPGPKF
                     VGPQGERFRDGKLSVDHSIDYCSSCGTCTLVCPQGVKVAEINHHARTAMKEQEGIPLRD
                     KLISRTTLMGMVMTPFAPVANWALDQKPIRYAVEKVIGIHRNAPMPKAQPHTFDHWFKH
                     HTPQPESGTKGQVIFFHGCAGEYFEVETSIHSVQILEHLGYEVLVPKHGCCGLALQSNG
                     LYDDSRKYVSKLTEQLRSVNRDAPIISASGSCAGMLKHEAEEILQMDTPELHDVSTRMW
                     DICEFLLDLHDKGELDEDFERFDVTIPYHAPCQLKSTGIGMPAIHLMELIPGVKVVESD
                     QPCCGIAGTYGLKKEKYDVAQAVGKPVFDFIERVNPELAACDTETCRWQLRTSTGANVV
                     HPIWLLHKAYGLS"
ORIGIN
        1 tccgggggga gcgcgtccgg cgccgacacc tccccggagc gcgacgcggc cgaggactcc
       61 actgcgggag gtggggaggg atgaggggga tctggatgct cgtgcgacgc gacgtcgcgc
      121 gggccacgag caacaccatg gccatcatcg tggtggtggg cctgtccgtc ctgccctcgc
      181 tcttcacctg gttcaacgtc atcgccagct gggacccgtt cgcgaacgtc gacgagctca
      241 cggtggcggt cgcgaacacc gacgagggat accagagcga cctcatcccc gtccggctca
      301 acatcggtga ccaggtcgtg tccgacctgc gggccaacga ggacttccac tgggtcgtca
      361 ccaccgagga ggacgccgtc gacggcacga agtccggcga gtactacgcg gcgatcgtcc
      421 tgccgcccga gttcagcaag gacatgctga ccttctacgc cccgggagcc acccgcaccg
      481 acatcaccta ctacaccaac gagaagaaga acgcgctggc ccccaagatc accggtcagg
      541 gcgccgaccg cgtgtccgcc ggcatcaaca gggtcttctc gcagacactc agcgagatcg
      601 gggtgaacat cctgtcctcg ctgtcggacc acctctccag tgaccagacc aaggtcctcc
      661 tcgcccgact cgagtcccac gtcggccaga cctccgccca actgcgttcc gccgccacga
      721 cggccgacac gttctccacg ctcatcgcct ccagcaggac actcctgggg agctcgaccc
      781 ggctggtcga ggccaccggg cagacgctgg acgacgccac cggggcgatc ggttccggac
      841 tggacgcagc cggctcactg aagtcgaccc tcgactccgc caccgcggga gtctcggcgg
      901 cactggaggt gagctcccag gggtgggcgg acctggctga caaggtggac gcggtcttcg
      961 ccgccgccga ccagcagacc accgacgggg tggacgtcct caacgggatg tcggagcagg
     1021 tgcaggccca gatcgacgcc tacgaggggc tcaggacacg gctcgagcag gacgtggccc
     1081 cgaacctccc ggacggcgcc ctcgacccgg cactggacgc cctcgacctc gccatctccc
     1141 accaggagga cgtccaggac gccctcgacc aggcggccgg gaagctctcc tcggagaact
     1201 ccggtgcgca ggccacccac cgggagctgg cgaggaccat cgccgaggcg aaggccgcag
     1261 tcgacaagct gcacgacgtg tacgacacgg acctcagggg gcagctcgac caactcggtg
     1321 tcgccctcgc cgccgcccgt tccgccgcgg gggacgtcgg cacggacctg gaccgggcag
     1381 cgtcgggcct cacgggcgcc tcggactcgc tggccgtcca gctcgcgcac gcccagacgg
     1441 tcacgacgtc cgtctccacc gacctggacg ccgccgccga gaccttcgac aggctcggca
     1501 cggccctggc ggaggcggcg gacaccggtg acctctccgc gctgcagggc gtcctcgggg
     1561 aggacccgtc ctccgtggcc gcctccctgg ccgcgcccgt gggtctcaac cgggtggccg
     1621 tcttcccggt ggcgaacttc ggcagcgcca tggcgcccct gtacacgatg ctggccctgt
     1681 gggtgggcgc gctgctgatg tccgtgtcca tccaggtcgg cgtccaccgc gacaccctcc
     1741 ccgacgggcc cgacctcgca ccgcaccaga agtacctcgg gcgctacggg atcttcgggc
     1801 tcatcgggtt cgtgcagagc accctggtgt gtctcgggaa cctggtgttc gtgcaggtcc
     1861 agtcggtgca cccgttgctc tacatgctga cgggatggat gacctcactg gtgttcaccc
     1921 tcaccgtgta cacggcggtc gtcgccttcg gcaacgccgg caaggcactg tgcgtgctcc
     1981 tgctggtcgt gcagatctcc acctcggggg gcgcctaccc cctccagctc ctccccgagt
     2041 ggttccagcg catcagcatc ttcctgccgg ccacgtactc ggtgcgggcc ttcaccgccg
     2101 cgatcgcggg gatctaccac gccgactact ggcactcgat cggtacgctc gcgctgttca
     2161 tcctgcccgc gctcctgctg ggcctggtgg tgcgcaagcc gctgatctcc ttcaaccgca
     2221 acctggccgc ggcactggag tccacgaagc tgatgtagtg gaggggctcg gccgggccca
     2281 gcccgcccgg taccatcggc gagtgcccgc aacgttccca gagatccgac agttcacccc
     2341 gcgcctggtc ccgaaccggg atcctcgacc gccgagcccg gaggcggccc ctggaagcgg
     2401 ttccgcagcc acggagcccg atgcgaggac acgagcctgg tgccaggccg tgtctgccgg
     2461 attccatgac cacgacccct ccgaggcggg gctgcgcagg atcgcctcgg cagcacagcg
     2521 ctccggcgcg ctgctgaccg aggtcagggc ggacaccacc agcccggatc cggcgctcga
     2581 ggaccgcccc gtgggaacgt tctccgtctt cgacgggctg gcgaacctcg gcgcgggaca
     2641 gatggttccg gcggggttga tcaccggtgt gaccgtccga ccgacccaca agcgtcgggg
     2701 gctcctcaga gcgatgatga cgctcaatct cgcccagctc gcagcacgtg atgtccccct
     2761 ggcgctcctc acggcgagca atgcccagct ctacggacgc tacggcttcc agacggttgt
     2821 gcgtgagtcg agggtgaccg tgtccccggg acccgggttc tcactgcgca ctcccaccac
     2881 gggtcgcgtc gaggtcgtga ccatgggctg gctcctgccg cggatgcccc aggtcttcga
     2941 ccggtaccac cggcggatgc gcggctcgac gactcgctac gaggggtact acgaggacct
     3001 ctaccacgac ccgaaggccg acagggtgga cggcaagttc gtcgcggccg tccacatcga
     3061 cgacaccgac aacctggacg ggtacgtgac cttcgagatc gagggatccc cggcgctcaa
     3121 ggtccgggaa ctcgtggcgg ccacgcccgc ggcggaactc gccctgtggg accacctcaa
     3181 ccgggtggaa ctcatcaagg agatcgtggc accgacggtc ccggaggact ccctcctccc
     3241 cctggcactc gtcgaccagc ggagcatgcg cacgacctcc gtgtccgatg cgctgtgggc
     3301 acgtgtcctc gacccggtcc aggtgctgga cgcgaggccg tacacggtcg cggcgcgcgg
     3361 ggcgcacctc caggtcgcat tcgccgtcga ggacgagctc ggacacgcct cgggtgccta
     3421 ccgggtcgtc acggcacccg agggcgtgca ggtcacgaga cttgcgggtc cggagtcagc
     3481 tccggctggt cctgacatcc ccacacctgt tcgcctcacg gtccaggcgc tctcggcgct
     3541 ggcgttcggg tccgccacgg cctccgacct cgccggggcg cagatgatca gcggggcggg
     3601 cgagggtgag ctggaggtca tggatgccct gttcgcaccc gtggggcgtg ccggcttcat
     3661 gtcgcacttc tgaggctgcg tgggcggggt cgccctcgtc ggtggacggc ccacctcacc
     3721 cccgcgccgg caggccccgg tcctccggtc cgtagcgtcg cccggtgtag cgggggtgca
     3781 ggaggttctc cggggtgagg atcgcgtcga tctgctcctc ggtgagcagg tggcgttcga
     3841 ggaggaccgc gcgcaccgac ttgcccgtgc gcgccgcctc cttgcccacg gagtcgccca
     3901 tgtggtggcc gatgatgtcg ttgaacaggg tgacgatccc gatggagttc atgacgtatt
     3961 cccggcagcg ctgttcattg gccgtgatgc cgacgacaca cttctcccgc agggtcgcca
     4021 cggcgttggt caacaggttg agggactcga acatcgcctg ggccagaccc ggttccatga
     4081 cgttgagctg cagctgaccg gcctccgcgg cggccgtcac cgtcacgtcg ttgcccatga
     4141 ccttgaagca cacctggttg acgacctcgg gaatgacagg gttgaccttg gcgggcatga
     4201 tcgaggaccc ggcctgcatc tcgggcaggt tgatctcctt gagcccggcg cgcggcccgg
     4261 aggacagcag acgcaggtcg ttgcagatct tggagacctt catcgcgacg cgcttgaccg
     4321 cggagtgtgc tgcgatgtag gcgccgttgt cggaggtcgc ctcgacgagg tcctcggccg
     4381 acctgatcgg cagcccggag acctccgcga gcttctcgca cgccacgtgc gcatagccgt
     4441 cgggggtgtt aaggcgcgtg ccgatggcgg tggcgcccag gttgacctcc aggagcagtc
     4501 cctgggcgtt gtggaggcgg gtgacctcct cctccatgtt ggtggcccag ccgtggaact
     4561 cctggcccag gctcatgggg acggcgtcct ggagctgcgt gcgtcccatc ttgaggacgc
     4621 cctcgaactc ctcgcccttc gcgtggaagg ccgtcacgag cgcacgcacc tcgtcgatga
     4681 gggcgtcgat gcggacgtcg acggccaggc ggaacccggt ggggtaggcg tcattggtgg
     4741 actgggactt gttcacgtcg tcgttggggt ggatgacgtc gtagcgcccc ttgtcgaacc
     4801 cggcgagctc gagggccagg ttggccacga cctcgttcgt gttcatgttg accgaggtcc
     4861 cggcaccgcc ctggaagacg tcgacgggga actggtccat gcacctcccg tgctcgagga
     4921 tctcgtcgca ggcggccacg atcgcgtcgg cgacgtcgaa ggggagcacc ccgagctcct
     4981 tgttggccag tgcggcggcc ttcttgacca tgaccatgcc acgcacgagc tcgggttccc
     5041 cggagatcgt gtgccccgag atccggaagt tctccacggc gcgcacggtg tgcaccccgt
     5101 agtacgcgtc ggcgggcacc tcccgcctgc ccagcaggtc ctcctctgtc ctggtcctca
     5161 tcgctccacc tctccggggc tcccgcccca caacccgccg tgcggacgga ccgggacgcc
     5221 ctcgtccctc tggccccggc acacggtcct gctgccgctc cgggggcact tccgggtgcc
     5281 ggaccactgc cggcaccccg gcgggcgccc accgccctcc gacggtaccc gcaggtccgc
     5341 ccaccacgcg aggggccacg cagcggatcg cggtggacgg cgctggacgg cgctggacgg
     5401 cggtggatcg cagtggacgg cggtccccac gggagcatcc gcgtccgtcc cggtcacacc
     5461 gtcgagaagc cgccgtcgga ggtcagcacc tggcccacca cccatgaccc ctcgtcgctc
     5521 gccaaccagg cgatgaggtg ggccgggtcg gaggggtccc cgaaccgtcc gaagggggtg
     5581 gcggcgagga gctccgccac ctgctccgca ccgcggtcgg tggtcgcagg gtccaggtac
     5641 ccggtgttga cggggcccgg gtcgatggtg ttgagcacga tcccgagatc gaggagttca
     5701 gcggcgacgg tgcgggtcac ccctgccagt gccgccttgg aggccgcata cgcgacctca
     5761 ccgcgcatgg gggagtggac ctggccggag gtcatccaga acacctttcc cagcgggacg
     5821 cgtgctgccc ccgccccggc gccggcgtcc gggcggggcg tccgctcccc gggcagcgcc
     5881 gggcactgcc gccccccggc gagaccacgt gcgaaacccg ccgtcagcag cagcgtcgag
     5941 cgggagttgg tgtcccagtg ggcatccagc cgggcggcgt ccatgtccag gatcgacccg
     6001 tcgtggccgc tgagtgcgtg gttgcagacg aggatgtcga gtgagccggt cagggagcgc
     6061 gccgccgaga gcaggggctc gaccgtcccc gcgtcggaga ggtcggcgtc ggcctctccg
     6121 agtcgcgccc ccggtgccac cctctccccg agcccctcca ggagtgcgtc gaggtcatcc
     6181 gctccccagc gctggtcgtg gtcgtggcgc gcgaagtggt gcacgaagac gctcgcgccc
     6241 atgtccagga gtgccgcggc caccgcgtgg ccgatgcccc gcctccggga gaccccggtg
     6301 acgagggcgg tgtggcccgc gagggggagc tgggtggtgt gccggctcat gttgggcctc
     6361 tcagtcgtcc tcgtcatcgg agggggtggc gggtccgcgc ctggcctgga tctcgatctg
     6421 ttcggagtcg aggaggctca gggcgtaccg cagggtacgc gaggagtagc tccgtgaggc
     6481 gcgcgcggct gcgagggcgc gacgctgcgc ctggatggcg aggagccgca gctcccggta
     6541 ctgggcgaag atgtccggtg tggtggcggc ggactcggcg cgtgacaggc gcatccggtc
     6601 gacgtccaca tgggcacggt ggaggacgcc gggatcgtac gggttgccgt cacggcggcg
     6661 cagggcaggg tcgtcgaggg cggccagtgc ggccccgtcc agtgaggccc gcagcgcgat
     6721 ccggtcggag accggaggtg cggtgtcccc ggccaggccc agggcccgcg cgagtgcggg
     6781 gagcgtggag ccctggacca gcagggtccc tgccgcgaca ccgaaggcga cgagcacgag
     6841 gagcgcgcgc tggggaatcc cggcgggaag ggactgggcg gccgccagcg tcaccacgcc
     6901 ccgcatcccg gcccacacga ggagggtccc ctcgcgggca cccaggggct cggcggtgaa
     6961 gtagtcgatg tcggcggagt gccgcgagag gcggcggtgc cacctggcga tccgttccct
     7021 gggcggggcc gtgtgctggg tcaccgcgag cctgaagcgc cgcttcagct tccacgcagt
     7081 cggctccggg agggagctga ggtccaccag ggaggggcca cgcggtgcgg cagtgcgcgg
     7141 tggggtcgtc ggccggcccc cgggcaccgc cgggtcgggg acgccgggtc gtgccccggg
     7201 gcctctgcgg tccccacgag cggtgggcga gggcgcgaag tgtgagcgca gctcgcggta
     7261 ggcgtcgcgc agttcctgac cacggcgcat gcgccggttc agccaggcca gcagcggcac
     7321 caggaacagc gcgcggagca cgaggatgag ggccacggcc agcgtggcga tgcccagggc
     7381 catccagagg ctctcgtgct ccttgcggac ctcggtgacc aggccgaaga gctcgaggcc
     7441 catgacgagg aacaccgcgc cctcgaggag gagctcgacc gtgcgccagt tggaggcctc
     7501 ggaccggcgg tcgagggggc tcaggtgggt gggagccccg ttgcccgtga ccagtccggc
     7561 agtggccacg gccaccagtc cggaggcacc cagcgcctcg gtggggagga acgccaggaa
     7621 gggcaccgcg aaggagacgg cggtggagag caccgggttc gccagccacc cacgcagcag
     7681 gagcccgccc ttcccgatgg ccacgccgaa cacgacggcg accgccacgg cgtagaggaa
     7741 gctgcccccc acctgccaca ggggcaccgt cgcggccgtg gcggcgatcg cggagcgcat
     7801 gaggaccagc gaggtcgcgt cgttgaggag gctctcaccc tccagcaccg tgacgatgcg
     7861 cggggagaca cccagcctgc gcacgatgga ggtggccacg gcgtcggtcg ggctgaggat
     7921 ggctcccagg gcgatgccga tggacaggct gatgccgggg atgacggcgg cgaagacgac
     7981 gccgagcacg agtgagctga tgagcacgag gaacacggac agtcccccga tggccgtgaa
     8041 gtcccgacgg aagtccatgg agggcaggct gaccgccgtc gcgtagagga ggggaggcag
     8101 gacccccgcc aggatccact cgggctcgac ggtgatggcg gggaccgccg gcacgaagga
     8161 gacaccgact ccgaggagca ccagcaggag gggggtggcc acgccgacct tcggggcgag
     8221 gcggtggacg aggacgatgg cgaggacggc caggacgacg acgagggcga ccgaggtgac
     8281 ctcagcgtcc gctgcgtcca cggcactccc tcccgtgcgc gctgcccgtg cgcgtcactt
     8341 ccccggacac cgtatcccgc gaagggcccg ccccgcccgg tgtgtccgcc gccacgcggt
     8401 ctgccggtcc gctgacccgc gccgtgctgc tccgcgccgt gctgacctgt ggcccgcacg
     8461 tcggtcagtg cgtggggcgg gccagcgcgt cggcaggtca gcgcgtcggc gggtcggcgg
     8521 gcactgcccc gccgtcgtcc tgtgtcggtc ggggcgtggg cgcgaaggtc tcggggtgtg
     8581 agggggtgtg gaggacgggc ggcggggtcg tggggcgtcc ggagggcaca cctccggacc
     8641 agaccgtgtc ggggtcgaag tgcgaggggt cggacggggc cggaggcggg cccgggggac
     8701 cgacggcact ggccgcgcgc ctgcgggaga tccgccatgc gcgcaggagg acgaggccga
     8761 ggacagcggc ggccgtgggt acgaggaaga ggaggaagac gatggccctc gtcatctcgg
     8821 gataggagac gtcctggccg gtctccatca gcagcgaggt cacggtcagg cccgctccga
     8881 gcaccaccag cacccacagg aggactcgca ggaccgggat cacgaggcgg tcgaccatgg
     8941 tcgggacacc ctcctgcggg gtcaggcgcc ggggtgggcg gtgtaccgtc ctcgtcgggg
     9001 tgcacgacgg acgtgcgcgg accccacgct atcccggacc cgcgggcgtt gcagtcggag
     9061 ggcgtggcag tcggagggcg cggcagcgac gtccggtgcg gcggtgacgg gcctggccgc
     9121 cgagggcggg ggagcacccc gcgcgccggt ccggggtcgt cctcaggggg cccgtccgcc
     9181 tgggccattg gtcacgggtg gggcaaactt cgctctcacg tcatcgagat gcacgtttgt
     9241 gcacgcggtg tgggcaattt gtatcgcgca ggtccgtagg ctgaacatgt aggcaatacc
     9301 ggtgcaggtg gcgggtgccc gagcgtccag accagggacc tcgacccggg cgccggtgct
     9361 cggcggcatc gcggccgcag tgcaggacgg gaaggaacac gtggtgaaga cgatccagac
     9421 ggacgtcgtg gtcatcggag gcggttcgac cggcgccggt gtggtccgcg acgcggcgat
     9481 gagggggtac cggacggtcc tggtggaccg ggcggacctc gggcagggca cgacgggccg
     9541 cttccacggc ctcctccact cagggggcag gtacgtggtc tccgacccgg agtcggccac
     9601 cgagtgcgcc caggagaacg cgatcctgcg caggatccag gcaggggcgg tggaggacac
     9661 gggcggcatg ttcgtcacca cccccgtgga ctccgaggag ttcgccgacg gctacgtggc
     9721 cgcctgccgg gccgccaagg tccccgtcga ggagatctcg gtggccgagg ccctgcgtcg
     9781 tgagccgcgt ctgaaccccg gcaccaagcg tgccttcgcc gtccaggacg gcacggtgga
     9841 cggctggcaa ctggtgtggg gcgcggtgcg ctccgccgag gcctacggtg ccaagatcct
     9901 cacctaccac cgcgtgaccg cgatcgagca cggtgacggc caggtccgcg ccgtggtcgc
     9961 ccacgacgag cgcgcggggg aggacgtccg catcgagtgc tccttcgtgc tgaactgcgg
    10021 cggtccctgg gccgggaaga tcgcggccat ggccgagtgc cacggggtcg acgtggtccc
    10081 cggtgcgggc atcatgatcg cgatgaacca ccggctcacc cagtcggtgc tcaaccggtg
    10141 catctacccc gccgacggcg acatcctggt ccccgtccac ccggtgtgca tcatcggcac
    10201 cacggatcag aagaccgacg acccggacca cctgccgatc ccgcgcgcgc aggtccagca
    10261 gatgttcgac tcgggggagc acatgatccc cgggttccgc cacgcccgcg ccctgcacgc
    10321 ctgggccggt gcccgcccgc tggtgcgcga cagccgggtg tcggcctccg acacccgcca
    10381 catggcccgc ggcatgcacg tcgtcgacca cgaggaacgc gacggggtca agggtctgct
    10441 gacgatcgcg ggcggcaagc tcaccaccta ccggctcatg gccgagcgca tcgtggacca
    10501 gatgtgcgag cagatgggcg agcagcgcga gtgccacacc gccgacgaac ccgtcccggg
    10561 gtccgaggac caccacctct acaccctcgg tcaccgcctc cacgacgtcg agaccgagac
    10621 gaaggccccc ggtggccagc agatcatctg cgagtgcgag ctcgtcaccc ggtccatgct
    10681 ggagaaggtc atggacgggc tgggggaatt caccctcgac gacgtgcgtc gccaggtgcg
    10741 cctcggcatg ggcccctgcc agggcgggtt ctgcgcctcg cgcgccaccg gcatcgccca
    10801 tgagcgcggc gacatcgacg ccgcgcgtgc caccggcctg ctgcgactgt tcatgaagaa
    10861 ccgctggatc gggttgtggc ccatcctgtt cggtgaacag gtgcgccagt gcgccctgga
    10921 caactggatc tacgagggca cgctcgacct cgagcacctg cccgagcccg ccgaggaggt
    10981 cgtgcgatga gtgacgtcgt cgtcatcggg gcaggactgg ccggcctggc cgccgccgtc
    11041 cggctccagg agcagggtcg cgaggtcgcc ctcgtgacga aggggatcgg tggcctgcag
    11101 ctgggccagg gcaccgtgga cgtgctgggg tacacccccg cgcccgtggc agagcccctt
    11161 gccgccgtgg acgcctaccg ctccgagcac ccggaccacc cctacgggca cttcccggga
    11221 acagaggtgg gggacgccct cgcgtggctg gggagcacgg tgggggaggg actcctggtc
    11281 ggggacggac agcggaactt ccgtctcccc accgcggtcg gcgccctgcg tccgacggcc
    11341 ctggcccagc cgtccatggt ggccagcgag cccaccgacg ggcgcagcta cgtgttcgtc
    11401 ggtctgcggc gcctcaagga cttctacccg gacctggtgg ccgcgaacct cgcgcgccag
    11461 accacgccct cgggtgagcc gatcagggcg cgcgccgtcc acgtggacct ggaggtccgc
    11521 gagggcgagg cagacaccag cggattgaac ttcgcccgcg ccctcgaccg tcccgaggtc
    11581 cgccagcacc tgtgcgcgct ggtggcaccg ctgctcgagg acggcgacac cgtcgggttc
    11641 ccggcagtgc tcggtgtcga ggacacggac gcctggcgcg acatcgccgc gcgtctcggg
    11701 cacgacgtgt tcgaggtgcc gctgcccccg ccctccgtgc cggggatgcg cctcaacgag
    11761 cgcctcacgc gtctggtcaa gtcgcgctcg cgcctcatcg tggggtcgag ggtgctcggc
    11821 tacgaggccg aggacggaca cgtcgtgtcg gtgaccatca agtccgccgg ccaccaccgc
    11881 cagctgcgcg cggacgagtt cgtcctggcc accggtggtt ttgagtccgg cgctctggcc
    11941 atggactcct acgggacggt gaccgagacc accttcggcc tcccactggt gggcaccggc
    12001 ggagagctgg tgcacgccga ctactggggc accgaacaac ccctcttccg ggtgggcgtg
    12061 gccgtcgacg acgccatgcg tcccctcgac gaggacgggg ctcccgtcct cgacaacctg
    12121 cacgccgtgg gcggactgct cgccggtgcc acgcggtggc gggagaagtc cggcgacgcc
    12181 atcgccctgg tcagcgccct gcgcgcagcc gattcgatcc tcgggagcaa gtgatgagca
    12241 acgagacgat cctcgacctg gagtccttcg ggctgcgttc cagcctggac gcctgcgtca
    12301 agtgcacgat ctgcgagacc cagtgcccgg tcgcccgggt cacgcccctc ttcccggggc
    12361 cgaagttcgt cggcccccag ggggaacgct tccgtgacgg caagctctcc gtggaccact
    12421 ccatcgacta ctgctcctcc tgcgggacct gcaccctggt gtgcccgcag ggggtcaagg
    12481 tcgcggagat caaccaccat gcgcgcaccg ccatgaagga gcaggagggc atcccgctga
    12541 gggacaagct gatctcccga accaccctca tgggcatggt gatgaccccc ttcgcccccg
    12601 tcgcgaactg ggcactcgac cagaagccga tccgctacgc ggtggagaag gtcatcggca
    12661 tccaccgcaa cgcgccgatg cccaaggccc agccccacac cttcgaccac tggttcaagc
    12721 accacacacc ccaaccggag tcgggcacga agggtcaggt catcttcttc cacgggtgcg
    12781 cgggggagta cttcgaggtc gagacctcca tccactccgt gcagatcctc gagcacctcg
    12841 gctacgaggt actggtgccc aagcacgggt gctgcggcct ggccctgcag tccaacggtc
    12901 tctacgacga ctcccgcaag tacgtctcga agctcaccga gcagctgcgc agcgtcaacc
    12961 gggacgcccc gatcatcagc gcctccgggt cctgcgccgg catgctcaag cacgaggccg
    13021 aggagatcct ccagatggac acccccgaac tccacgacgt gtccacccgc atgtgggaca
    13081 tctgcgagtt cctcctggac ctccacgaca agggggagtt ggacgaggac ttcgagcgtt
    13141 tcgacgtgac gatcccgtac cacgccccct gccagctcaa gagcaccggc atcgggatgc
    13201 cggccatcca cctcatggag ctcatcccgg gtgtgaaggt cgtggagtcg gaccagccct
    13261 gctgcggcat cgccggcacc tacggcctca agaaggagaa gtacgacgtc gcccaggcgg
    13321 tgggcaagcc cgtcttcgac ttcatcgagc gggtcaaccc ggagctggcg gcctgtgaca
    13381 cggagacctg ccgctggcag ctgcggacct ccaccggagc gaacgtcgtc cacccgatct
    13441 ggctgctgca caaggcctac ggactgagct gagctgacgg cccctgcccg ggctgggccc
    13501 gggcagggtg tcccggcaca gggatgcctg ccggaggtgg tccggcacac acggcttccc
    13561 actgggtggt gaacctggca ctgagtggcg tacttcgcgc tgagtggtgg acttcccacc
    13621 gaacggtggc cctgtacccc caccactcgg tgggaagtcc accgttcgg
//
