LOCUS       c00011_NZ_CABK..       14008 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKTP010000011.1 Clostridium polynesiense isolate
            MGYG-HGUT-01479, whole genome shotgun sequence.
ACCESSION   c00011_NZ_CABK..
VERSION     c00011_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:45:19
            Original ID  :: NZ_CABKTP010000011.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14008
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14008
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5954:11932]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5955..11932
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
     cand_cluster    1..14008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /kind="single"
                     /product="Glycine_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_reductase"
                     /region_number="1"
                     /rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /tool="gutsmash"
     CDS             2..319
                     /locus_tag="ctg11_1"
                     /transl_table=11
                     /translation="YNRYKYYKIIRSRSILPLYKHALKRIKLLGYKKSLWNTDREFVKA
                     INNESLKRTMEELVEFVYEEYYGGLINDSDKRILEQKLEESIKISYKNNIKYYIYRFIL
                     Y"
     CDS             501..1358
                     /locus_tag="ctg11_2"
                     /transl_table=11
                     /translation="MKYKLICTDMDGTLFNSNKEISERTKEAIKKAHQLGVKIVLATGR
                     IYNFAALYADTLGIEAPVISANGAFVRSKNHKDVIYKKVIGLENNMKILAIFNKYGIVP
                     HYYTPDSAFSGELVQAAKVYMERNKLVPEELRVNVNIIKGQDSWEKVFKEHDEEILKCI
                     GMDDDLEKVLKAKEELKKIDGIEVSSSFINNIEINGREVTKGRAVEITAALYDIDREEI
                     ICIGDNENDLSMIEYAGLGVAMGNAEEHVKQKADYVTDTNDEDGVAKVIEKFVINEHIN
                     GNNR"
     CDS             1462..1929
                     /locus_tag="ctg11_3"
                     /transl_table=11
                     /translation="VNLNIVLFQPEIPQNTGNIARTCVLTNSKLHLIKPLGFSLDEKHL
                     KRAGLDYWQYLDLEVHESYEELRSKYPEGVFYLSTTHGSKYYDDVKYNSGDFIIFGRES
                     SGLPQYIKDENGERCIRVPMLQTSTRSLNLSNTVAIVAYEALRQNGFPNMK"
     CDS             1946..2779
                     /locus_tag="ctg11_4"
                     /transl_table=11
                     /translation="MTKIKIITDSTCDLNQELIKKYDIEVIPLIINIGDESYLDGVDID
                     IKTLLHKMDVENASASTSQIIPGRFHEVYKKYVSEGYSIISIHLSSEMSGTYHSACLAK
                     ESFENADINIIDSRNVTSGLGLLVLKAAKLAEEGKTAKEIVSIIEELKPRVKSLLGFES
                     LDNLVRGGRLSKTAGIIGSMLGIKVVLGVVDGNMAVKEKFRGSKKAIKYIIENFEKSGY
                     IPGEPVMLLSIENKDIYEPLKQYLVSNNIEYIDNQVGCTVGIHSGPKACGIFFLS"
     CDS             complement(2810..3673)
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="MNKIIYLIIIMTFLTSCSSRNRVNITDPNQDNTGNYSSEAPLPES
                     PPADENSKLPNEVTGKRNENVAQPEVKPPRTKTEDPSKSSGKPPNSGSSTQTSPSAGGT
                     DSSAGNASNDTPGINAVPETPAPPKDNVNIATGTLPAIPMKYSFDYMEQVENRVLELVN
                     AERAKAGLNPVVFNDKLRQASRYKSNEMLQYNYFSHNSPYTNSPMEVVKGFGHSYNTIG
                     ENIWMMGASNSAALRTSVTAEKIVSSWMNSSGHRANILNNSFTKMGIGIVSGDNGKSYA
                     AQIFTD"
     CDS             4137..4514
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MIEKFFIITNNPLCRDSFKDSYKVNYLEGTVSEVFSAARDYIHKG
                     HILLTHPLLSSIKPNETPYRSILISQASKPGVDMNSLEIMESSIHTLEKFLRDFKTPKW
                     NERILEDFQFIDYDLTLNAIR"
     CDS             4591..5544
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_7"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.5e-53, bitscore:
                     171.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHIYDTIIIGGGPAGLSAGLYAARSKMDTLLIEKGKFGGQTATT
                     AELENYPGSIEECTGPGLIERMRKQAEEFGTSFVKDEIVEVELEGTTKVVKGIKETYKA
                     KTIIIATGAYPRLAGFKNEMELRGRGVSYCATCDADFFTELDVAVIGGGDSALDEAIYL
                     TKFAESVTIIHRRDQFRAAKSIVEKALANPKIKVIYDSIVLEAKGDEILEGLVLKNVKT
                     EEISDLTVDGCFVFVGYLPITEIFKGKIKLTERGDIITDEEMRCSVPGVFAAGDVREKS
                     LRQVITAAADGAIAATTAEKYIEANASLYTEELVLS"
     CDS             5590..5922
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MLELNKDNFESEVLNYSEKPVFVDFWGDKCEICKDLMPGVHELEN
                     KYGDKIKFASLNISSARRLAIGQKVLGLPTMIIYKNGERAKVITPDKISNLADVESFIK
                     EEYDNL"
     CDS             5955..7241
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: Glycine_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_9"
                     /sec_met_domain="Glycine_reductase (E-value: 2.5e-219,
                     bitscore: 717.8, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLELGYIYIKDIQFGDSTRVENGVLYVNKEELLKEVSGDERIKS
                     IDFDIARPGDETRIIPVKDVIEPRVKVNGKGGIFPGFISKVDTVGSGRTHVLKGAAVVT
                     TGSIVGFQEGIIDMSGEGAKYTPFSKNFNLVVICEPVDGILKHDHEEAVRMIGFKAAAY
                     LGKAGAKVEPDDVKAYETLPLLKQVEMYPELPKVVYVYMLQTQGLLHDTYVYGVDAKKI
                     IPTFIYPTEVFDGAIVSGNCVSACDKNPSYVHMNHPVIEDLYERHGKDINFLGCVITNE
                     NVYLADKERSSNMTAKLVEFLGADAVIISEEGFGNPDADLVMNCNKISEKGIKTVLITD
                     EYAGQDGSSQSLADSTPKGDAVVTGGNANEVITLPPMKKVIGHPDAANIIAGGYVGSLR
                     EDGSINAEIQVITGATSEVGFNYITAKGF"
     CDS             7260..7385
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_10"
                     /sec_met_domain="GRDA (E-value: 9.4e-22, bitscore: 67.6,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQNKKVIAIGDRDGIPGPAIEECVKSAGAEVVFASTECFV"
     CDS             7401..7724
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_11"
                     /sec_met_domain="GRDA (E-value: 3.3e-52, bitscore: 166.4,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLEIQQRVKDLTEKYGPENLIVVLGGAEAEASGLSAETVAAGDP
                     TFAGPLAGVELGLGVYHVVEPEIKDECDAAVYDEQCGMMEMVLDVDAIIEEVKAIRDQY
                     SKY"
     CDS             7746..8789
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_12"
                     /sec_met_domain="GRDB (E-value: 2.1e-180, bitscore: 589.5,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLKVVHYINQFYAGIGGEEKADHKPELREGFVGPGMGLNGLLKGE
                     AEIVATIICGDSYFNENMDEAKEEILNYVKQYNPDLFIAGPAFNAGRYGVACGAIAKEV
                     EEKLNIPVLTAMYTENPGVDLYKKSLYIVETKNSAAGMRAALPVMAKLALKIAKGEEIL
                     SPEEEGYIERGIRKNYFASERGSKRAVDMLVKKLKGEEFKTEFKMPVFDRIEANAPIVD
                     MKKAKIALVTSGGIVPKHNPDHIESSSASKYGEYSIEGVQELTEATYETAHGGYDPTYA
                     NTDPNRVLPVDVLRAMEKEGKIGSLHNLFYSTVGNGTAVASSKKFGAEIGEKLKNAGVD
                     AVILTST"
     CDS             8859..9047
                     /locus_tag="ctg11_13"
                     /transl_table=11
                     /translation="MCTVTPISLTVGANRILPTVAIPHPLGNPALSHEEEYELRYKLVD
                     RALKALETEVEGQKIFE"
     CDS             9222..10757
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_14"
                     /sec_met_domain="ACP_syn_III (E-value: 1.1e-12, bitscore:
                     37.9, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFPVIKKASYILVNTPDMILHNGTTLTAERESNPDSELLTKVPE
                     NLRSFEDVVAYAPNQTYIGNTTPEQLSERPRPWHGEKVEGADRFGEFGEIMPQDEFYGL
                     MKVSDVFDLVLLEAGFTEEVRGKFAAHPILNKKADALKAGVDIEEINKLIGNGVAEGLY
                     INGKVVGCVKRAHEFDKNLSSHIIVENLAVKASGVLALMHLVNNSDVKAEEIDYIIECS
                     EEAIGDMNQRGGGNIAKSLGEVAGLKGATGTDMRGFCAGPTHALINAASLVKSGIFKNV
                     VIVGGGATAKLGMNSRDHIKKGLPVLEDCLGGFAVLISENDGVNPVLRTDIIGRHTIGH
                     GASPQAVLEALVLEPLEKAGLKITDIDKYAPEMQTPDITEPAGAGDVPTQNYKMIGALA
                     VKKAQLDRKELPEFVKKHGYPGYAPTQGHIPSGVPIIGHARNRIMQDEMNNFMVIGKGS
                     LFLGRMTNLFDGVSIVVEKNSGVKEVQQEISREEIKQMVADSMKDFAAYLMNK"
     CDS             10772..11932
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: FA_synthesis"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_15"
                     /sec_met_domain="FA_synthesis (E-value: 2.4e-51, bitscore:
                     164.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKDVLQKVIGEVFNEIADNIKDGSYGKKTKIGLTILGSEHGVDV
                     MVKAAEIAKARYPQIDIILIGPRVTEDFTVVEASDAEEGHKKMVELLNSGEIDGCVTQH
                     FEFPIGTSTMGKVVTPAKGNEMIIASTTGTSAINRVEAMVLNSIGGLAVAKANGIKSPK
                     LGILNIEGARKVEIILNELKENGYEIEFSSSQRADGGAVMRGNDLLMGTPDVMVCDSLT
                     GNLLIKVFSSFSTGGNYETTGAGYGPGVGDGYDKVINIVSRASGAPLIAEAIKFCSESA
                     KNNLPALVKKEFEAAKSAGLSSVLEKHLKPKAEVKEEEVKMPPKKVVTYSIAGIDILEL
                     ENACRTLWKEDIYSESGMGCTGPIILVPEEDGKKAEDILVKSGYKA"
     CDS             12250..13410
                     /locus_tag="ctg11_16"
                     /transl_table=11
                     /translation="MPNIIIINYIKWYLKLYLGGVYIMKKRLVAALSAFAVAATVLAGC
                     AKPASEPPKTGGTDTAKKLKVGLVTDQGGANDGSFNESADRGIKNAAKELGIERLNPIE
                     SKQQEQYQPNLKTMAGTADLVVGAGFMMMESMKEISKQVSDKKFLIVDAVVENPNVASF
                     LFKEHEGSFLAGVMAGMLTKTNKIGFIGGKEGDVIGRFESGFIAGVAATNPEAAKGLMP
                     KDAKSHGQFVKYIDDFSDQSKAKEAANMLYNSGADIIFHAAGGAGEGLFKAAQEKKLWA
                     IGVDSDQAITLPAYKDVLLFSMIKKVDAAVLQGIKDLKDNKFPGGKLVNLGIKEDGVGI
                     SETVHANVTAEAKDLAKKAEAQIKEGKIVVPGTLEELLKFQAPALK"
     CDS             13480..14007
                     /locus_tag="ctg11_17"
                     /transl_table=11
                     /translation="MEKVIEMKNITKVFPGTIANDDVNFDLQKGEIHVLLGENGAGKTT
                     LMNVLYGLYQQEKGEIYVKGQLANIKSPKDAIKLGIGMVHQHFMLVHNFTVAQNMVLGY
                     ETKKGIVMDMKVAEEDTKKLSEKYGFNIDPKAVIQDMTVGQQQKVEILKALYRGAEILI
                     LDEPTAVLTPQEV"
ORIGIN
        1 atataataga tataaatact ataagataat tagaagtaga agcatactac ccttgtataa
       61 acatgcttta aaaagaatta agcttttagg atacaaaaaa agtttgtgga ataccgatag
      121 agaatttgtt aaagctatta ataatgaaag cttaaaaaga actatggagg aattggtgga
      181 atttgtatat gaagaatatt acggtggact gataaatgac tcagataaga ggattttgga
      241 gcaaaaactt gaggaatcaa ttaagatttc ctataaaaat aatataaagt attatattta
      301 taggtttata ttatattaaa aagatatcaa tataataata taaaagatga tatttaagca
      361 ttgctctgca atgcttaaat atttatactt ttatatcttt gttcttattt atttaacttt
      421 atttttaaag ataaataata ttatttgata taatataata tggaattata taaaaataat
      481 tttacaaagg agctataaga atgaaataca aattaatatg taccgatatg gacggtacac
      541 tttttaatag taataaagag ataagtgaaa gaacaaaaga ggctataaaa aaggctcatc
      601 agctaggagt gaaaattgta ctcgctaccg gtaggatata taattttgct gctttatatg
      661 cggatacctt agggattgag gcacctgtaa tctccgccaa cggtgcattt gtaaggagca
      721 aaaaccataa agatgtaata tataaaaagg ttatcggact tgaaaataac atgaaaatac
      781 tagcaatttt taataaatac ggtatagtgc ctcattatta tactcctgat tcagcttttt
      841 caggagaact ggtacaggca gctaaagtat acatggaaag aaataaactg gtacctgaag
      901 agttaagggt aaatgttaat attataaaag gtcaggacag ctgggaaaaa gtatttaaag
      961 agcatgacga agagatattg aaatgtatag gaatggatga tgatctagaa aaggttctga
     1021 aggctaaaga ggagctgaag aaaattgatg gtattgaagt ttcaagctcc tttataaata
     1081 atatagaaat taacggtaga gaagtaacta agggaagagc agtggaaata accgctgcat
     1141 tatatgatat agacagggaa gaaataatat gcattggaga taatgaaaat gacctttcta
     1201 tgattgaata cgcaggactt ggagtggcta tggggaatgc agaagaacat gtaaagcaga
     1261 aagccgatta tgtcacagat acaaacgatg aagatggggt tgccaaagtt attgagaagt
     1321 ttgttataaa tgagcatatt aatggaaaca atagataaat aatactagtt taattcaaca
     1381 ttcttatttt gactaaaata tattattatt gtagtatatt taagtaaaga attttatctt
     1441 acttagggtg gaggtatatt tgtgaattta aatatagtat tatttcagcc ggagattcca
     1501 caaaacactg gaaatattgc aagaacatgc gtactgacta actctaagct tcaccttata
     1561 aagcctcttg gatttagtct tgatgagaag catttaaaaa gggcaggact tgattactgg
     1621 cagtatttag atctggaggt acatgaaagc tacgaagagt taagaagtaa gtatccggaa
     1681 ggagtctttt atctttcaac cacgcatgga agcaaatatt atgatgatgt aaaatataat
     1741 tccggagact ttattatttt tggaagagaa tcctcaggtt tacctcagta tattaaagat
     1801 gaaaatggtg aaagatgcat tagagtacca atgctgcaaa caagtacccg ttctcttaat
     1861 ctatctaaca cagtagctat agtagcatac gaagctcttc ggcaaaatgg gtttccaaat
     1921 atgaaataag ggggattatc tttaaatgac aaaaattaaa attattactg acagcacttg
     1981 cgacttaaat caagagttaa tcaaaaagta tgatatagag gtaattcctc ttattataaa
     2041 cataggggat gaaagctact tagacggagt agacatagat attaaaacgc ttctacataa
     2101 aatggatgtg gaaaacgctt ctgcttccac ttctcaaata ataccaggca gatttcatga
     2161 agtgtataaa aaatatgtaa gtgaagggta tagtatcata tccatacatc tttcttcaga
     2221 gatgagcgga acctaccatt cagcttgcct agcaaaagaa agttttgaaa atgctgatat
     2281 taatatcata gattcaagaa atgttaccag cggattagga ttactggtgc ttaaagcagc
     2341 aaaattagca gaggaaggca aaacagcaaa agaaattgta agtattatag aagaattaaa
     2401 accaagagtt aaaagcctat tgggttttga gagcttagac aatttagtgc ggggtggaag
     2461 gttgtcaaaa acagctggaa taataggttc tatgcttgga ataaaggttg tattaggtgt
     2521 agtagatgga aatatggctg ttaaagagaa gttcagaggc agtaaaaaag ctataaagta
     2581 cataatagaa aactttgaga aaagcggata tattccaggg gaacctgtaa tgctcctgag
     2641 catagaaaat aaagatatat atgagcctct gaagcagtat ttagtaagta ataatatcga
     2701 atatatagac aatcaagtag gatgtacagt aggaatacat tcaggtccta aggcctgcgg
     2761 aattttcttt ctttcataaa taaaacagcg gaacactccg ctgctttttt taatctgtaa
     2821 atatttgtgc tgcatagctt tttccgttat ctcctgatac gattccaatc cccattttgg
     2881 taaaactatt atttaatata ttagctctgt gtcctgagga attcatccag ctggatacta
     2941 ttttttccgc agtaacagaa gtccttaggg cagcagaatt tgaggcgccc atcatccata
     3001 tattttctcc tatggtatta tagctgtgtc caaagccttt cacaacttcc ataggggagt
     3061 ttgtataagg agaattatgg ctgaaatagt tatattgaag catctcattt gatttatatc
     3121 tggaagcctg cctgagctta tcattaaaca caacgggatt aagacctgcc tttgctcgct
     3181 ctgcattaac aagctcaaga accctatttt caacctgctc catataatca aagctatatt
     3241 tcattggaat ggctggaagg gtgcctgtag ctatattcac gttatctttt ggaggagctg
     3301 gagtttcagg tactgcatta ataccggggg tgtcgttgga ggcatttccc gctgagctat
     3361 ccgtacctcc tgcagaaggt gaagtctgag tactactgcc ggaattagga ggcttacctg
     3421 aggatttgga gggatcttct gtcttggttc ttggaggttt tacctcaggc tgtgcaacat
     3481 tttcatttct ttttcctgta acctcattgg gaagctttga attttcatca gctggaggcg
     3541 attcaggaag aggggcttca ctgctgtaat tgcccgtatt atcctgatta ggatcagtta
     3601 tattcactct gttcctgctg ctgcatgaag ttaaaaacgt cattataatt attaaataaa
     3661 taatcttatt cataataatc accctgcctt taatagattg atgtaaaaaa atgcattttt
     3721 catttttatt tatttaatta actatatttt tagtttttcc aatgggatgt atttatattt
     3781 ataatagtta aaaatataat aaagttatag atatttttaa aaacatagta tataattata
     3841 aatgaaagtt ttgaaaatgt gatggatgat attctcggga gagaaccttt aagggtggcc
     3901 gaaggaataa gtaatatctg ccaaatatta tgaatctctc aggcgaaagt accgtgaatt
     3961 gacataactc tggaaagcat agcaccgaag gagtaaatct ctcaggttaa aagacagagc
     4021 ataggcgcta gccttgcttt gtcttttttt catgaaaaga taacggtttc atagttaagt
     4081 tttccatgaa agaaaaaaat cattaaaaaa gaataatttt aaataacgga ggaaaaatga
     4141 tagagaaatt cttcattata accaataatc cgctgtgccg ggattctttt aaggattcct
     4201 ataaagtaaa ttacttagaa ggcactgtgt cggaagtttt cagcgcagcc agggattata
     4261 tccataaagg acatattctt ttaactcatc cgcttttaag cagcattaag cctaatgaaa
     4321 ctccttatcg ctcaatactt atatctcagg cttccaagcc tggagtagat atgaactcat
     4381 tagaaataat ggagagttca atacatacat tagaaaaatt tcttagggat tttaaaactc
     4441 caaagtggaa tgaaaggata ttagaggatt ttcaattcat cgactacgat ttaacattaa
     4501 atgcaataag ataactcaag tcctatttgt tataaaatta acaaattctg cgacttttta
     4561 atattaataa tatatttagg aggggaattt atgtctcata tttatgacac aataataata
     4621 ggtggtggac ctgcaggatt atcagctgga ttatatgctg ccagatcaaa aatggatacg
     4681 cttcttatag aaaaaggaaa atttggagga cagacagcaa ctacagctga attggaaaac
     4741 tatccaggat ctatagagga atgtaccgga ccagggctga ttgaaagaat gaggaagcag
     4801 gctgaagaat tcggaacatc ctttgtaaaa gacgaaatag ttgaagttga actggaaggt
     4861 acaactaaag ttgttaaagg aataaaagaa acatacaaag caaaaactat aataatagct
     4921 acaggagcat atccaagact tgccggcttc aaaaatgaaa tggagctgag aggaagaggc
     4981 gtttcctatt gtgctacctg tgatgcagac ttctttactg agcttgatgt tgcagttata
     5041 ggcggaggag attctgcatt agatgaagct atttatctaa ctaaatttgc tgaaagtgta
     5101 actataatac ataggagaga tcagttcaga gctgctaagt caattgttga aaaagcttta
     5161 gctaatccaa agataaaggt tatatatgac tccatagtgc ttgaagctaa aggtgacgaa
     5221 atacttgaag ggttagttct caaaaatgtt aaaacagaag aaataagcga tttgacagtg
     5281 gatggctgct tcgtgtttgt aggatatctt ccaataacag agatatttaa aggtaagata
     5341 aaattaactg aaagaggaga tataattaca gacgaggaaa tgagatgctc ggttcctgga
     5401 gtatttgctg caggagatgt aagggagaaa tccttaagac aggttataac cgcagcagct
     5461 gatggtgcta ttgcagcaac taccgctgaa aagtatattg aggcaaatgc cagtctttat
     5521 actgaagaat tagttttaag ctaacaaatt tataacaata taaaatcatt aagaaaggat
     5581 gggataaaaa tgttagaact gaataaagat aactttgaat cagaagtatt aaattattca
     5641 gaaaagcctg tatttgttga cttctggggt gacaaatgtg aaatctgtaa agatttaatg
     5701 cctggagttc atgagctaga aaacaaatat ggagataaga ttaagtttgc cagcctgaat
     5761 atcagcagcg caagaaggtt agctatagga cagaaggttt taggacttcc aactatgata
     5821 atctacaaaa acggcgaaag agcaaaagta ataactcctg ataaaataag caacctggca
     5881 gatgttgaaa gcttcattaa agaagaatat gacaatctat aattccaaaa taaaatgtta
     5941 aaaggggtgg gaccttgaaa cttgaattag gatacattta tattaaagac attcagtttg
     6001 gagactctac aagagtagaa aacggagttc tttatgtaaa taaagaagag ctattaaaag
     6061 aagtttccgg agatgaaaga ataaaaagca tagactttga tattgcaaga cccggagatg
     6121 aaacaagaat tattcctgta aaggacgtta ttgaacctag agtaaaggta aatggcaagg
     6181 gaggaatatt cccaggtttt ataagcaaag tagatacagt aggttcaggc agaacgcatg
     6241 tacttaaagg tgctgctgtc gttacaacag gaagcatagt aggtttccag gaaggtatca
     6301 ttgacatgag cggagaagga gcaaaataca ctccattctc aaagaacttt aatttagttg
     6361 ttatctgcga gcctgttgat ggaatattaa agcatgacca tgaagaagct gtaagaatga
     6421 ttggctttaa ggctgctgct tatctgggaa aagcaggagc aaaggtagaa cctgatgatg
     6481 ttaaagctta tgagacatta cctcttttaa agcaggttga aatgtatcct gagcttccaa
     6541 aggtagtata tgtatatatg cttcaaactc agggcttact ccacgacact tatgtttatg
     6601 gagtagatgc taagaagata atacctacct tcatataccc tacagaagtt tttgacggtg
     6661 ctattgtaag cggaaactgt gtttctgcct gcgacaaaaa cccaagctac gttcatatga
     6721 atcatcctgt aatagaggat ctttatgaaa gacatggtaa ggacataaac ttcttaggtt
     6781 gtgtaattac aaacgaaaac gtatatcttg ccgataagga aagaagctca aacatgactg
     6841 ctaaattagt agaattctta ggagctgatg cggtaatcat atcagaggaa ggctttggta
     6901 accctgatgc tgaccttgtt atgaactgta ataaaataag cgaaaaaggc attaaaacag
     6961 ttttaatcac tgatgaatat gccggacagg atggaagttc acaatcctta gcagactcca
     7021 cacctaaagg tgatgctgta gttactggag gtaatgctaa tgaagtaata acccttccac
     7081 cgatgaagaa agtaatagga catccagacg cagctaatat aatagccggc ggatatgttg
     7141 gaagcttgag agaagatggc tctataaatg ctgaaataca ggttataacc ggtgctacat
     7201 cagaagttgg ctttaactat atcactgcaa aaggattcta atatatagga ggtaaattta
     7261 tgttacagaa taaaaaagta atagctatag gagatagaga tggaatacca ggaccagcta
     7321 tcgaagaatg tgtaaaaagt gctggtgcag aggtagtatt tgcatctaca gaatgctttg
     7381 tttgaaccgc cgctggcgca atggatctgg agatccaaca aagagtaaaa gacctaactg
     7441 aaaaatatgg tccagaaaat ctaatagttg ttttaggcgg agcagaagca gaagcttcag
     7501 gactttctgc tgaaacagta gctgctggag acccaacttt tgcaggtcct ttagcaggag
     7561 ttgaacttgg attaggagtt tatcatgtag ttgaacctga aattaaggat gaatgtgatg
     7621 ctgctgtata cgacgagcaa tgcggaatga tggaaatggt gcttgatgtt gatgccatca
     7681 tagaagaagt aaaagcaata agagatcaat actcaaaata ctaaacccaa aaggggggat
     7741 aggctttgtt aaaggtagta cattatatta atcaatttta tgctggtata ggtggagaag
     7801 aaaaagcaga ccacaaacca gaattaagag agggcttcgt aggtcctgga atgggattaa
     7861 acggactgtt aaaaggcgaa gctgaaatag tagcaactat aatatgcgga gactcatatt
     7921 tcaacgagaa tatggatgaa gcaaaagaag aaatattaaa ttatgtaaaa cagtacaatc
     7981 cagatttatt tatagcagga cctgcattta atgctggaag atatggagtt gcctgcggtg
     8041 ccatagcaaa agaggttgaa gaaaaattaa acatacctgt acttacagct atgtatactg
     8101 aaaaccctgg cgttgatcta tataaaaaga gtctttatat agttgaaaca aaaaacagcg
     8161 cagcaggaat gagagctgct cttccagtaa tggcaaagtt agctttaaaa attgcaaagg
     8221 gtgaagaaat actttcaccg gaagaagaag gatacattga aagaggaatt agaaagaact
     8281 actttgcatc agaaagaggt tctaagcgtg cagtagatat gcttgttaaa aaattaaaag
     8341 gcgaagaatt caaaactgaa ttcaaaatgc ctgtttttga cagaattgaa gctaatgcac
     8401 caatagttga catgaaaaaa gcaaagattg ctcttgtaac ttccggtggt atagttccta
     8461 aacacaatcc tgatcacata gaatcctcca gtgcttcgaa atatggagaa tacagcatag
     8521 aaggagttca ggaattaact gaagctacct atgaaacagc acatggcggt tatgacccaa
     8581 catatgctaa cacagatcca aacagagtac ttcctgtaga tgttttaaga gctatggaaa
     8641 aagagggaaa aataggatca cttcataact tattctattc tacagtaggt aacggtactg
     8701 cagttgcttc ctcaaagaag tttggagcag agataggtga aaagttgaaa aatgccggag
     8761 tggacgcagt aattttaacg tctacttgag gaacctgtac acgttgcgga gcaacgctag
     8821 ttaaagaaat tgaaagagct ggtttaccag tagttcatat gtgtacagta acacctatat
     8881 ccttgacagt tggagctaac agaatacttc caacagtagc tattccacac ccattgggaa
     8941 atccggcact ttctcatgaa gaggaatatg aattaagata caaattggtt gacagagctt
     9001 taaaagcttt agagactgaa gttgaaggac aaaaaatatt tgaataatta atttttaaac
     9061 acggaaactt acaaaaatac tatgggtaca aggaagggaa ctttacaatt aaacccttac
     9121 aaggtgcttt ccgtattttt gtaaatccgt gtttaataaa gttataagaa tgtttgtata
     9181 attaaaatgt aaaattatta aagtgatatg gaggttttac aatgaatttt cctgttatta
     9241 aaaaagcatc ttatatactt gttaatactc ctgatatgat actgcataat ggaacaaccc
     9301 ttacagctga aagggaaagc aatccggatt cagagttgtt aactaaggta ccagaaaatt
     9361 taagaagctt cgaagatgtt gtggcttatg ctccaaacca aacttacata ggcaacacga
     9421 cacctgaaca attatctgaa agaccaagac catggcatgg cgaaaaggtt gaaggtgctg
     9481 acagatttgg tgagttcggt gaaataatgc ctcaggatga attttacggt cttatgaagg
     9541 tatctgatgt ttttgactta gtactattgg aagcaggatt tactgaagaa gtaagaggaa
     9601 agttcgctgc acatccaata ttaaataaaa aggctgatgc tcttaaggcc ggagttgata
     9661 ttgaagaaat aaacaagctt attggaaatg gtgttgctga aggactatat ataaatggca
     9721 aggttgtagg ctgcgttaaa agagctcatg aatttgataa aaatctttct tctcacataa
     9781 tagttgaaaa cctagctgtt aaagcatcag gagttttagc tttaatgcat ttagtaaata
     9841 acagcgatgt aaaagcagaa gaaattgatt atataattga atgttctgaa gaagctatcg
     9901 gagatatgaa ccaaagaggc ggaggaaata tagctaaatc tttaggtgaa gttgcaggat
     9961 taaaaggagc aacaggtaca gatatgagag gtttctgtgc aggtcctacc catgcactta
    10021 taaatgctgc ctccttagta aaatcaggta tatttaaaaa tgttgttata gtaggcggcg
    10081 gtgctacagc taaacttgga atgaactcaa gagatcacat caaaaaagga cttccggttt
    10141 tagaagactg ccttggaggt tttgcagtac tcataagtga aaatgacggt gttaatcctg
    10201 ttttaagaac agatataata ggtagacata caataggcca tggagcttct ccacaggcag
    10261 ttttagaagc attagttctt gaacctttgg aaaaagcagg actaaaaatt acagatattg
    10321 ataagtatgc tccagaaatg cagacccctg atattactga acctgcagga gcgggagatg
    10381 ttcctactca aaattacaaa atgattggag cccttgcagt aaaaaaagct caattagata
    10441 gaaaagaact tcctgaattc gttaagaagc acggatatcc tggatatgca cctactcaag
    10501 gacatatacc atccggtgta ccaattatag gacacgcaag aaacagaata atgcaggatg
    10561 aaatgaataa ctttatggtt ataggaaaag gaagtttatt cttaggaaga atgacaaatt
    10621 tatttgatgg tgtttcaatt gtagttgaaa agaacagcgg tgttaaagaa gttcagcagg
    10681 agatttccag agaagaaata aagcaaatgg tagctgattc aatgaaagat tttgcagctt
    10741 acttaatgaa taagtaagga gcgtgaaaaa aatggaaaaa gatgtacttc aaaaagtaat
    10801 aggtgaggta tttaacgaaa tagctgacaa cattaaagat ggaagctatg gaaagaaaac
    10861 aaagataggc cttactattt taggctcaga acatggcgta gatgttatgg taaaagctgc
    10921 tgaaatagca aaagcaagat atcctcaaat agacataata cttataggac ctagggtaac
    10981 ggaggatttt acagtagttg aggcttctga tgcagaggaa ggccacaaga aaatggtaga
    11041 gcttttaaac agcggtgaaa ttgatggatg tgtaacccag cattttgagt tcccaattgg
    11101 aacatctacc atgggtaaag ttgttactcc agctaaaggt aatgagatga tcattgccag
    11161 caccaccggt acctctgcaa taaacagagt agaagctatg gttttaaact caataggcgg
    11221 tttggcagtg gctaaagcaa atggtattaa atcaccgaaa cttggaatac taaatatcga
    11281 aggtgcaaga aaggttgaaa taatacttaa cgagctgaag gaaaatggct atgaaataga
    11341 attttcaagc tctcaaagag cagatggagg agctgtaatg agggggaatg acctcttgat
    11401 gggtactcct gacgttatgg tctgcgactc tctaacagga aatcttctta taaaagtatt
    11461 ttcctctttc agtacaggag gtaattatga aactacagga gcgggctatg gacctggagt
    11521 aggagatggc tacgataagg ttataaatat agtttccaga gcatccggag ctcctcttat
    11581 agctgaagca attaaattct gctctgaaag tgcaaagaat aatcttcctg ctttagttaa
    11641 aaaggaattc gaagctgcaa aatccgcagg actttcttct gtacttgaaa aacatttaaa
    11701 gccaaaggca gaggtaaaag aagaagaagt gaagatgcct cctaaaaagg ttgtaaccta
    11761 ttccatagca ggtattgata tacttgaatt agaaaatgcc tgcagaacct tatggaagga
    11821 agacatttat tctgaaagcg gaatgggatg taccggtcca atcatacttg ttccagaaga
    11881 agatgggaaa aaagccgagg atatcttggt aaaatcaggt tataaagctt aattgagtga
    11941 aatactaaca aattatctgt ttactaagtt aaaataattt gtactttatt tctataatta
    12001 agcatatata atgaaataaa gtaaatatta tttcaaaaat atataataat aattgttaaa
    12061 ttgaaataaa aagtacaaaa attttactct ttaattttaa aagatattta aaaaagttaa
    12121 cccttatgct ataattacta aagtaaataa taaatgataa agtttacaat tgatatttcg
    12181 ttcattattt tttaaaataa tgaacgaaat atagtgtttt ctttcatttt tttatttata
    12241 atatatataa tgccaaatat aattattatt aattatatta aatggtactt aaagttatat
    12301 ttaggagggg tttatattat gaaaaaaaga ttagttgcag ctttatcagc ttttgctgta
    12361 gcagctacag tacttgctgg ttgcgctaaa cctgcgtctg agcctccaaa aactggtgga
    12421 acagatacag caaaaaaact taaggttgga cttgtaactg accagggcgg agctaatgat
    12481 ggttccttca acgagtcagc tgacagggga ataaaaaatg ctgctaaaga gcttggaatc
    12541 gaaagattaa atccaatcga atcaaagcag caggaacaat atcaaccaaa ccttaaaaca
    12601 atggctggaa ccgctgattt agtagttggg gcaggattta tgatgatgga atccatgaag
    12661 gaaatttcaa aacaggtttc agacaagaaa ttcttaatag tggatgctgt tgttgaaaat
    12721 ccaaacgtag cttcattctt attcaaagag catgaaggtt ctttccttgc tggagttatg
    12781 gcaggaatgc ttactaaaac caacaaaatc ggttttatag gcggaaaaga aggagacgtt
    12841 attggaagat ttgaatcagg ttttatagct ggtgtagctg caacaaatcc tgaagcagct
    12901 aaaggcttaa tgccaaagga tgcaaaatcc catggtcaat ttgttaaata tatagatgac
    12961 ttctcagatc aaagcaaggc taaagaagca gccaacatgc tttataactc aggagcagac
    13021 attatattcc acgctgctgg cggagccggt gaaggattat tcaaagctgc tcaggaaaag
    13081 aaactttggg ctataggtgt tgactccgat caggctataa cacttccagc ttacaaagac
    13141 gttttattat tctccatgat taaaaaagtt gacgcagcag ttcttcaagg tataaaagat
    13201 cttaaagata acaagttccc aggcggaaag cttgttaact taggtattaa agaagacggt
    13261 gttggtatat ccgagactgt acacgcaaat gtaactgctg aagcaaaaga tttagctaaa
    13321 aaagctgaag ctcaaatcaa ggaaggtaaa atcgtagttc caggaacatt agaagagtta
    13381 ttaaagttcc aagctcctgc tcttaaataa ttgtaggaaa aatgtttaag gctagatgtg
    13441 agagcatcta gcctcttcta taacaggagg agagtaataa tggaaaaagt aattgaaatg
    13501 aaaaatatca caaaagtttt tccaggtact atagcaaatg atgatgtaaa ttttgacctg
    13561 caaaaaggag agattcacgt tcttttggga gaaaacggag caggtaaaac tactctcatg
    13621 aacgttttat acggtcttta tcagcaggaa aaaggggaaa tatatgtaaa aggtcagctt
    13681 gcaaatatta aatctcctaa ggatgctatt aagcttggaa ttggtatggt acatcagcat
    13741 tttatgcttg tgcacaattt caccgttgcc caaaacatgg tgctgggata tgagacaaaa
    13801 aagggtatag taatggatat gaaggtagca gaggaagata ccaaaaagct atctgaaaaa
    13861 tatggcttta atatagatcc taaagctgtt attcaggata tgacagttgg acagcagcag
    13921 aaggtagaaa tattaaaagc tctatataga ggcgcagaaa tactcatact ggatgaacct
    13981 acagcggttc tgacacctca ggaagtta
//
