LOCUS       NZ_CP014230.1          23273 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP014230.1 Desulfomicrobium orale DSM 12838 chromosome, complete
            genome.
ACCESSION   NZ_CP014230
VERSION     NZ_CP014230.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:59:45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2409872
            Orig. end    :: 2433145
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23273
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2419872:2423145]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13273
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23273
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23273
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="7"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(411..647)
                     /locus_tag="ctg1_2212"
                     /transl_table=11
                     /translation="MGRVHVKDLSLTGAGLLCEGNAPNRGDMLVLRFFLDDDVKTKIEK
                     KIQVESVRGQRVGASFVDEKLFDAALGKYVLSR"
     CDS             1134..3029
                     /locus_tag="ctg1_2213"
                     /transl_table=11
                     /translation="MDVVIRLDRLKALGYVHSRLYGPKKDHPPPLWKLMENSARTSFLL
                     PVLPAFLLWMACCFLPMPAAAAPVEYTVEIPSLPDDLDDLLRSVSDSVALIGSPPDTAG
                     LLRRRMEKDRENFAEALKSRGYFGSEVLASLETTKSPHVIRFHVELGPCFIFDAPALEI
                     IPPDTGLGALLRPLLKSIKAGSGYQAALIPDTETAMLDELRKNGYPSPSTGARRVVADH
                     ATGQVHVRFIIRPGGRAVFGRTHIEGLERLNEEFAARHIAWKEGQLFDIRKVDDTRTEL
                     IRTGLFRSVRIETEHAENADTADMCLSLLEAPRRTVRAGLWYYSDLGPGTSAGWTNRNL
                     FRGGQELHFDAEISRNLNSASAAFVLPAMWHPDQTLGLQAKYQSENTDSYDSVNLAFSG
                     IMRRKFPDHLQLGYGLAYRLSEVKKEDTRRFHLLSAPLIAEYTTVTEPLDPSSGLALSA
                     RAEPFTDLKLRDSSFVSWNIAARSYWPLLKDNSLVLAARGHIGVLAGASRDNVPEDMLL
                     YAGGGGSIRGYAYQYAGDLDEEDKPLGGLSAVDFSAELRLRFSRTFGFVVFGDGGGAFS
                     KRNPLDVSSFFWGAGTGIRYYTPIGPLRLDVAVPLKRRSGVDAPFHFYVSLGQAF"
     CDS             3029..7258
                     /locus_tag="ctg1_2214"
                     /transl_table=11
                     /translation="MFRSKLFRAAKRAAYVMAALTLPACLALLWLFGTAGGRQTLLDLA
                     DAATASENFHLRARGLNLGREWTLESLHLSDASGVWLELHQIRLQPRLRSLLKGHVHLE
                     HCGIVHTILHRLPESEEGATDTETSLPPVRVARVDLDRVELRPEALGQAADLSVRGELE
                     LNPHEGRTNLSIIRLDRSQDALHVSGSFQEHPEQLALDVRMHEAPEGLLHTLLDLEQLS
                     GNATQGVTLSLRGQGSLTDWPLSLSLRLAGALELNATAALKLTEEPEADLRGQVRLGTA
                     LQDTARLTDPDIGFFARLSWLKDELRLTRLRVENAAAAMDGNATWNQAREEMRAAVRIE
                     GRDIAPLLPPDISPGPAALNAMLLFSAEGLRLDADIVAKDWNMSGYRLSAANINASLAR
                     DSGSDWDFRTAFAIHAPELPPDLQAISGTATGKGSGTTWRLDNLEAATRTVSLRASGKL
                     DSNLNSSVTVVMRDFSAASKMAVSGRVAASADGRFTPEGPAFRGRLALHAEGISGLPPE
                     AAQLVGPNPGLHAELFLSPEKMHVRDLKLRGNTRLAGNGTFEPETGAFSSVFDAVFPEL
                     CVADMHLAPGAAAQGQAAGNSTDLGLDLRASAPMFSAGQFHITNATASARITGPHRPEY
                     DLRIRALTEGEPAEFAARVLMDGPAILLRNATLSLPQNKLTVTGTLNTDSNIFQGHGHL
                     DSASLAPLGRLAGQDMDGKLTLCTDFLEEKNRQAVRIEGNGNALSMAGIHIGHAALHGS
                     TALPDPLRSADADLRLGHIHRDSLHLDACRIQARSRNDGVHLVFGLDQNATQSAITGKA
                     LASWDERRLRASLNSLVGTLLGQKLRLAAPVNITVESERTAWTRGELHFGPAVLSGSGN
                     IAANGVDIDASLENMDPALFRLLRDDLPQGDIQARLAVRGAPENPDARMDVRGRNIRIS
                     APGRKDPLTVDVSGHATLNPGRFRSTLTLNGQDGAMTADAELSVPVRGPVTALDIAGDA
                     PLTGRMRGGLDLTLLPHLLLLDDQSLSGRAVMDFRLGGTASTPTLSGTAHVGDGRYENY
                     RSGTRLESISATATARDAEVDFILNATDGRQGTLSAQGSADLKPLSYVCDIRLDRCELV
                     NTDLIRSTADGRLRVWGNGGAAAVNGTLKPDPAYVQLPSDMSGVTRVEVEEINVPGGDT
                     SSGKDSGMPVNLNLRVDVPTRLFVRGRGLDSEWSGRLDITGPQTAPSVRGQMNLLRGRF
                     EFLDRMFDLTKGTISLSGETPPNPFLDILGECRVMDTLIQVRINGPARNFKLALSSAPP
                     LPQDELLSMILFGRSLREISPLQAVRLAQAAAALTGVGGAGMGVFDSIKAALGLQEVDI
                     GRDDEGNTAVGIGGYVGGKYYVRTQSSVSGQDRTKIEIQLSPKISVETEIGSDSRQGGG
                     VNWRKDY"
     CDS             7473..9653
                     /locus_tag="ctg1_2215"
                     /transl_table=11
                     /translation="MAPLLPSWTGSFSGRFFPGTNFIDASFDFDFLNDLPSLYANLRHW
                     LSSMDSVVAVYIGILVLIVLIILYAIQTHRTRVQALRLSLLVHNAPVMIRAHDKRGVPL
                     FWNRECERVTGYPARRIVNNSDSWTLLYPDPALRDKTAAMRKAPARDYTDARNPVTCAD
                     GSTRIITWFSISESHPIPGWYSWETGLDITEQQAAAEALKERDLRQKAILDNIPDVAWL
                     KDRKLRLVAVNRRFCTLMQRTEHALLGRTIMDFWPAEFSGPCAETDRLVLREGRPLWQE
                     ERIPSSSSEEIWHETFRTPIYGTSGEIIGIAGIGRDITEKRKTAQELLLAKQRAEEANK
                     TKSEFLANMSHEIRTPLNGILGMLQLMTSTAMTEEQSTYIRTAITSSRRLSRLLADILD
                     ISKIEAGQLEIIREPFAIRELQEALQDIFQLTANRTGVPLRVRIAEDVPPYLMGDEARL
                     RQIIFNLVGNAFKFTTRGSVSVDIDCLRKTTEHCRLLITVTDTGAGIPGSMQDKIFDSF
                     TQVEGSASRSHAGVGLGLAIVRRLIHLMNANLAISSAPGEGTEICISLPLDIARHYEQR
                     AEAEKAIQTSSSPLRFLVAEDDQINQLAITRLLEKKGHRVHCVANGLTLLEEVKSGAYD
                     MVLMDVQMPGMDGIEATRHIRLLPEFERVRTIPIIALTACAMSGDRERFLRSGMDGYIP
                     KPVDWNILSHVIAVVAEKRRARNVRDLPRPRA"
     CDS             complement(9625..9867)
                     /locus_tag="ctg1_2216"
                     /transl_table=11
                     /translation="MILSSSQIRALKERNDEELRKGRHAKYGYPAHTIQDLLQTLEATK
                     KEKKKWKQLAQDRGRALQEIAALTQGVMPSAGEDL"
     CDS             complement(10001..10990)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2217"
                     /sec_met_domain="IlvN (E-value: 1.6e-76, bitscore: 252.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.8e-65, bitscore: 215.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVYYEKDADLNTLKDKVVAIIGYGSQGHAHAQNLRDSGVRVVVG
                     QRPGGANWQLAREHGFEPVTAAEAAKKADLIQILVQDQYQPKVYEEEILPNLSAGKTLV
                     FGHGFNIHYNQIVPPKDVDVVMIAPKGPGHLVRREFEKGGGVPCLVAVHQDATGQALAK
                     ALAYAAGIGGTRSGVLETSFAEETETDLFGEQAVLCGGVSELVRAGFETLVQAGYQPEI
                     AFFECMHELKLIVDLLYEGGFKKMHHSISDTAEYGDYVTGPRVINAESRKAMRAVLEEI
                     QDGTFARNWILENKAGLPSFLAKRRRSHQHQVERVGDELRSMMAWLKK"
     CDS             complement(11087..11575)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2218"
                     /sec_met_domain="ALS_ss_C (E-value: 6.9e-27, bitscore:
                     90.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRHVLSILVENEPGVLSRVAGLFSGRGFNIESLNVGPTLEPGVSH
                     ITICTIGDEQIIEQIMKQLHKLITVIKVVDLTHQQAVEREIVLMKVGADDAKRAEVLRI
                     ADIFRCKVVDVSPTELTLELTGDRNKIKAVVALLQRFGVKDFVRAGTVAMRRSMQLAD"
     CDS             complement(11585..13273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2219"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.7e-55, bitscore:
                     182.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMLTGARILMECLKREGVDLIFGFPGGAVIDVYDELPNHPFRHIL
                     VRHEQAAVHAADGYARASGKVGVCLVTSGPGATNTVTGIATAYMDSIPLVVITGQVPTH
                     LIGNDAFQEADIVGITRSCTKHNYLVKNVAELAATIKQAFYIARTGRPGPVLIDLPKNV
                     ITASTEFSYPETIHIRSYNPNYSPNRKQLRKAAELIAQAERPAIYAGGGVISSDSAAEL
                     VRLAELCQCPVTTTLMGLGAFPGDHPLWLGMLGMHGTYTANMAVNSCDVLISVGARFDD
                     RVTGRVSAFAAGARIIHIDIDPTSISKNVVVHVPVVADCKLGLQGLIEEADRISGVDWA
                     AKHEKWNAALAEMRAVHPLGYGKTGERIKPQQVVEKIFEISRGEAIITTEVGQNQMWAA
                     QFYTYRKPRTLLTSGGLGTMGYGFPAAIGAQLAFPDRLVVDVAGDGSIQMNIQELATAV
                     SYQVPVKIVILNNGYLGMVRQWQELFYKKNYCSTCLHANPDFVALARAYGAEGFLVEKS
                     EELESTLRAAFAHPGPVVVDVRVEPEENVAPMVPAGAALAEMLLV"
     CDS             complement(13280..13510)
                     /locus_tag="ctg1_2220"
                     /transl_table=11
                     /translation="MEQQDLELIAANLAHDEELRALWEAHVGFEKALERYSGKAALSPA
                     EELEVKEYKKKKLAGKTRIQGLLEKYKRQEG"
     CDS             complement(13522..13839)
                     /locus_tag="ctg1_2221"
                     /transl_table=11
                     /translation="MSGRPVCVVPAKGGWRISVWVQPGAKKTEFAGMHGEHVKIRLQAP
                     AVDNKANTALTFFVAEALGLRPRQVTIESGHGARKKSLVVHAEEEPDWNLFSAGDTANL
                     N"
     CDS             complement(13844..14137)
                     /locus_tag="ctg1_2222"
                     /transl_table=11
                     /translation="MPVFSSLLAAAFYVADSVLTLYFWIVLVSAAMSWINPDPYNPIVR
                     GIRTLTEPVFYRVRKALPFSYAGGMDFSPVVVLLGIKFIQVFMGQLVARMAI"
     CDS             complement(14158..14826)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2223"
                     /sec_met_domain="HAD_2 (E-value: 3.1e-26, bitscore: 89.8,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGRDTPASSPGCGVRPVRGLVFDCDGVLFDTRDVNRFYYNHILE
                     KLGLAPMTAEEEDYSFMHTVDVSLARLVPAELMPRLPEVVGHMTYDEFIDRMIPEPGLG
                     DLLESLQIRGVRMAVNTNRKNSMEKVLERFHLTGFFSPVMTAAKVSRPKPHPEGLLRIA
                     EEWGMPVEHMAYLGDSSVDQDAARGAGVPFWAYKNRGLRAELHVDSFHELRQWLESVGQ
                     "
     CDS             complement(14829..16481)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 379.8; E-value:
                     4.7e-116)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2224"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-114, bitscore:
                     379.8, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 9.1e-16, bitscore:
                     55.9, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKPVLRDMTLGQILDEAVAQYPENEAVVYVDRDFRMTYRDFGAL
                     VDNLAKGLMAMGVGKGEKVAVWATNVPYWVALQFATAKVGAVLLTVNTHYKKAELEYLI
                     RHSECENLVVIDSFRDTDYIQVVYDLLPELRTQERGYLRTEKFPDLKRVFFLGPEKHRG
                     MYSMPELLALSRMTSEEDYRKRQDSLDPHDVVNMQYTSGTTGFPKGVMLTHHNIGNNGF
                     WIGENQRFTSKDRVCLPVPLFHCFGCVLGVLAAVTHGATLVILEGFSPLLVLSAVEEEK
                     CTALYGVPTMFIAVLEHRTFARYDLSSLRTGIMAGSPCPVPVMEKVMDAMHMREVTICY
                     GLTEASPVMTQTRVHDSLAQRTQTVGRAMPEVEVRILDPDTGEEMLPGEQGEVCCRGYN
                     VMKGYFNNPDATAQAIDPDGWLHSGDLGTMDKDGYVTITGRLKDMIIRGGENVYPREIE
                     EFLYRMEGIKDVQVVGVPSRKFGEEVGAFIILKDGFDYAVEDIRDFCRGQISRYKIPKY
                     IAFIDEYPMTASGKIQKYRLRELAAQYFPEAMK"
     CDS             complement(16503..17072)
                     /locus_tag="ctg1_2225"
                     /transl_table=11
                     /translation="MSKEKLGMRVKRFREMNEITLEQLAERTGLSLSFLKSLEEDSVYP
                     SLGPLLKVARGLGVRMGTFLDDELGQDPLVVRLGGRVEDMAMQAQKGSSTDTRYYSLGR
                     GKTDRRMEPFFVELLPVAEAGRKLSTHEGEEFIVVQEGAVEVIYGGETIILSKGDSIYL
                     NSVVPHHVGCSGDAPASIYAVLYFPE"
     CDS             complement(17089..17829)
                     /locus_tag="ctg1_2226"
                     /transl_table=11
                     /translation="MMVHFPWLHPGLIHGPLPEGVVLFDPGVELASEFPRWRPENLPLS
                     GACARRLASEYVDFAQGLSRISDLRPYEAAGLEDFYTDTGMDIRSRLREKAAPEAASAD
                     DRRRRAQVALTLALSREEQFAALHGQEDRLARAQGGFAASLGLEDGDAFADQGVADALI
                     FPRAGSDLPWRGMFGPLLCLVPEGTRFFVSDPDVAGELLSLGLPREAGAGGEDFIHLRV
                     SPHDLEPAGDASLSAVIVVRPSEP"
     CDS             complement(17853..18224)
                     /locus_tag="ctg1_2227"
                     /transl_table=11
                     /translation="MVTNGHTSPIRLSGRGCRHWMGERCLYEEHLNPGLRRNFRCTVLE
                     GWEKILEEHVARSECFGLTAEEAGSIWERMAVCLEERWECPDFRPDGEASGPSCALLAG
                     DLCLLRLPPCTGRCRRYER"
     CDS             18356..18550
                     /locus_tag="ctg1_2228"
                     /transl_table=11
                     /translation="MFGIGIPELLIILVIVLIIFGANKLPEIGAGMGKAIKNFKKATNE
                     PEEIDVTAKSETSDTEKKS"
     CDS             18585..19697
                     /locus_tag="ctg1_2229"
                     /transl_table=11
                     /translation="MRPLLFWKCEKRRVTPISESRMPQARISSQRADPSAESSPEALPF
                     RVRGRLAPSPTGHLHLGNAWSFLLCWLAVRAAGGVLVLRMEDIDPDRSRPEYAAEIMRD
                     LDWLGLDWDEGPPGALYTQSTRLERYAEVLGTFMRDGLAYPCYCTRKELKSMASAPHAE
                     DMGPVYPGTCLGLTDAERRLREREGRRACLRLHGGEDTRFTDLARGPAHFGWAECGGDF
                     PLRRSDGVISYQLAAAVDDADQRITLVVRGRDILPSTPRQMLILRLMKAPLPRYAHVPL
                     LLDHEGERLAKRHQALTLKSLREAGIRPEAVTGYLACRAGLLPRPGSLSPLQLVPFFSW
                     DRLPRHDVRLEPDMLPRLRGLRLATAPCAR"
     CDS             19823..21604
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 373.6; E-value:
                     3.4e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2230"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-112, bitscore:
                     373.6, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 3.3e-20, bitscore:
                     70.1, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDKGISRVWLQHYDKEVSANLSYEHISMYEILARAAERHPERTA
                     LIFNNWRVSYRKLKVLVDLTGTNLRRSGVRPGDRVAIMLPNCPQAVISYWACLRLGAVV
                     VMTNPLYMEKELVHHFNDSGAATLITLDLLWNRIDSLRPRLGLERIFITSISDCLRFPL
                     NLLYMFKSRREHRLPDIPYGSSGVASWKSLLARTAVEPPHPIDPQKDLALLQYTGGTTG
                     VSKGVMLTHANLLCNARQCQAVLHGISEERETGQVILGLLPFFHIYGLTVCVNFGMLIG
                     ATLIPVPKFTPADVLKTISKKRPTIFPCAPSIFVALLQQKNLARYDLSSVRYCISGSAP
                     MPVPVMEKFNKLTGARIVEGYGLTEASPITHLNPLLGVNKNGSIGLPFPDTDAAIVDMD
                     VGSVPLPPGKIGELVIRGPQVMGGYWNRPDETASVLRNGWLYTGDIAYMDEEGYFFIVD
                     RKKDLIITGGYNVYPREIDEVLHEHPAVKEAVSVGINHRTRGEIIKAYIVLREGYTLTK
                     AEVLAFCREKLANYKVPKQVEFRDELPKSIVGKVLRRVIREEEERRGDHDGDCDDELTG
                     DGFEMKENQRGQEDESI"
     CDS             complement(22118..22318)
                     /locus_tag="ctg1_2231"
                     /transl_table=11
                     /translation="MLQYDRSLQVRGQFRLSGRPGQVDAESVGDAFAIGRVGLQAIGDM
                     PDFDLFRGIPMLPERLAATRR"
ORIGIN
        1 ccttccagct ccagaatgat ttcctccgaa tagtttgccg gctgatactg ccctttgagt
       61 tccgcattga attccccatt tttcaggacg atcggagacg gcgcttccca gccgggaaca
      121 ttcttgaatt ccacaagctg caaggcttcg gattgtgcct ctccggcacc ctgccactgg
      181 gtgaccacac gccactgggc gccgttacga gcggcttctt ccggctctat gaccacactc
      241 cgcacgaggc gaggcgagcc gaggggaaaa agttccggct ttatcgcgaa caacatgccg
      301 catccaatgc caaccaaaat caagagcgcc caaagagcgc cgccggtcct cttgcttgaa
      361 tccgaatgtg taccagccac gcgccacact cctcacagat acggattgaa ttatctcgag
      421 agaacgtatt tgccgagcgc agcatcgaac agtttttcgt ccacgaagct ggctccaact
      481 ctttgtcccc gaacggattc cacctgaatt tttttctcta tcttcgtttt tacatcatca
      541 tccagaaaga aacgcagaac aagcatatct ccccgatttg gagcgtttcc ttcacacaga
      601 agcccggcgc ctgtcaggga aagatccttt acatggactc ttcccatact cgtctcctgg
      661 ttcgatgcat ttaacagctc gccctcaaga gaagtttcct tgcggaaata ttgccgaaaa
      721 ttgaaagaaa cagtaaattt tccgctgcat ctggtacatg tcgcaccgac actccagtgg
      781 gcaacatctt ttattttttc cacattgacc tttttttcca acctgcaatg cgggcaagag
      841 aagattaccg aatctttctt gcggataagc acttccactg tcggattgtt actgtcgctc
      901 ataattatca tcatcaggga tttgaaaaac agccgcaaaa aatgcctcaa cggctcaatc
      961 ccgcaggaga gtgccgcaca catccccgca ggccggactc atgataggcg caagcgtttc
     1021 aaatatccag caatctgttg acgatcctga caaaactcaa ggcgcagcgc aatccattca
     1081 ttcaggaccg ccatgggccg cacgccgcac aatcgctgaa ccgacgcgta tcaatggacg
     1141 ttgttatcag actggaccgg ctgaaggctt tgggatatgt ccactcgcgc ctgtacggcc
     1201 cgaaaaaaga ccatcccccg ccgctttgga agctaatgga aaacagcgcc cgaacaagct
     1261 ttctcctccc cgtcctgcct gcttttcttc tgtggatggc atgttgcttc cttccgatgc
     1321 cggcagccgc cgcgcctgtg gagtatacgg tagaaattcc atctctcccg gacgatctgg
     1381 acgatctgct gcgctcggtt tcggacagcg tggcgttgat cgggtctccg cccgatactg
     1441 ccggactgct gcggcggcgc atggaaaaag accgggaaaa cttcgccgag gccctgaaat
     1501 ccagaggtta ctttgggtct gaagtcctgg ccagtctgga aacaacaaaa agcccgcacg
     1561 tcatccgctt tcacgttgaa ctgggcccct gttttatctt cgacgcaccc gcgcttgaaa
     1621 tcattcctcc ggatacgggc ctgggtgccc tgctccgccc gcttctcaaa tccatcaaag
     1681 caggctccgg gtaccaggcc gcgctgatcc cggacacgga aacggccatg ctcgatgaac
     1741 tgcggaaaaa cggctatcct tcgccctcaa ccggtgcgcg gcgggtcgtt gcggaccatg
     1801 ccacgggcca ggtgcacgtg cggttcatca tacgccccgg cggccgggcc gtgtttggcc
     1861 ggacgcatat cgaaggtctg gagcgcctga acgaggaatt cgcggccaga cacattgcct
     1921 ggaaagaagg acagcttttt gacatccgca aagtggacga cacccggacg gagcttatcc
     1981 gcacgggcct tttccgctcg gtgcgcatcg aaacggagca cgcggaaaac gcggacacgg
     2041 ccgacatgtg tctgtcgctg ctcgaagcgc cccggcgtac cgtgcgtgcg gggctgtggt
     2101 attactccga tctcggacca ggcacaagcg caggctggac aaaccgcaat ctgttcagag
     2161 gaggccagga gctgcatttt gacgcggaaa tctcccggaa tctgaacagc gcgagcgccg
     2221 ccttcgtgct tcccgccatg tggcacccgg accagactct cggcctgcag gccaagtatc
     2281 agtccgagaa cacggacagc tacgacagcg tcaatcttgc cttttcaggc atcatgcgcc
     2341 gcaaatttcc ggaccatctg caactgggat acggtctggc ctaccgactg tccgaggtga
     2401 aaaaagaaga cacccggcgc ttccacctgc tttcggcccc gcttatcgcg gaatacacga
     2461 ccgtaacgga gccgctggac ccgtcctcgg gtctggccct gtccgcccgg gcggagccct
     2521 tcacggatct gaaactgcgg gattccagct tcgtttcctg gaatatcgct gcgcggagct
     2581 attggccgct tctgaaggac aactccctcg ttctggccgc ccgcggccac atcggcgtgc
     2641 tggccggggc cagtcgcgac aacgtcccgg aggacatgct tttgtatgcg ggcggaggag
     2701 ggtccatccg cggatacgcc taccagtacg ccggagatct ggatgaggaa gacaagcctc
     2761 tggggggcct gagtgcggtc gatttctcgg cggagctgcg actgcggttc agccggactt
     2821 tcggatttgt cgtcttcggc gatggcggcg gcgcgttctc caaaagaaat ccgctggacg
     2881 tgtcctcgtt tttctggggc gccggaacag gcatccgtta ctacacacct atcggccccc
     2941 tccgtctgga tgtggccgtt ccgctgaaga gacgcagcgg cgtggacgca ccctttcatt
     3001 tttatgtcag cctcgggcag gccttctgat gtttcgaagc aaacttttcc gcgccgccaa
     3061 aagggccgca tatgtcatgg ccgcgctcac gcttccggcc tgcttggccc tgctctggct
     3121 cttcggtacg gcgggcggcc gccagaccct gctcgatctg gccgatgcgg ccacagcctc
     3181 ggaaaatttt catctgcggg cccggggcct gaacctggga agggaatgga cgcttgagtc
     3241 gctgcatctc tccgacgcat cgggagtctg gctggaactg catcaaatcc ggctgcagcc
     3301 aaggctccgg tctcttctga agggacacgt ccatctagag cattgcggca tcgtccacac
     3361 cattctccac cgtcttccgg agtcggaaga gggtgccacc gacacggaaa cgtccctgcc
     3421 gccggtacgc gtcgcgcgag tcgatctgga ccgcgtcgaa ctgcggccgg aagctctggg
     3481 gcaggcggcg gacctgtcgg tccggggcga gctggaactg aacccgcacg aagggcggac
     3541 caatctgtcc atcatccgtc tggaccggtc tcaggatgcc ctgcatgtct cggggagctt
     3601 tcaggaacat ccggaacagc tcgccctgga cgtacgcatg cacgaggccc cggagggcct
     3661 gctgcatacg ctcctcgatc tggaacagct gtccggaaac gccacccagg gagtcactct
     3721 gagtctgcgt ggacaaggta gcctgacaga ctggcccctg tctttgtccc tgcgtctggc
     3781 cggggctctg gagctgaacg ccaccgccgc cctgaaactg accgaagagc cggaagcgga
     3841 cctgcgcgga caggtccggc tgggcacggc attgcaggat acggcccggc tgaccgaccc
     3901 ggacatcggc ttctttgccc gcttatcctg gttgaaggac gaactgcgcc tgacccgcct
     3961 gcgtgtggag aatgcggcgg ccgccatgga tggaaacgcc acatggaacc aggccaggga
     4021 agagatgcgg gccgccgtac gcatcgaagg ccgggacatc gccccgctgc ttcccccgga
     4081 catttctccc ggcccggccg ctttgaatgc catgctcctg ttctcggcgg agggtctgcg
     4141 cctcgacgcg gatattgtgg ccaaggactg gaacatgagc ggataccggt tgagtgctgc
     4201 caacataaat gcttcccttg cgcgcgactc cggcagcgac tgggatttcc gcacagcctt
     4261 cgccatccac gccccggagc tgccgcccga cctgcaggcc atctccggta ccgccacggg
     4321 caagggaagc ggcaccacct ggcggctgga caacctggag gcggcaaccc ggaccgtcag
     4381 cctgcgcgcc agcggcaagc tggattccaa tctgaacagc agcgtcacgg tggtcatgcg
     4441 tgatttttcc gcggcgtcca aaatggccgt ctccggacgc gtggcggcct ccgccgacgg
     4501 ccgtttcact ccagaaggcc cggccttccg tggacggctc gccctccatg cggaaggcat
     4561 ttccggactg ccgccggaag cggcccagct tgtgggtcca aatcccggtc tgcatgcgga
     4621 actgttcctc tctcctgaaa aaatgcatgt gcgcgatctg aaattgcgcg gcaatacccg
     4681 ccttgccgga aacggaacct tcgagccgga gacaggtgca ttctcaagcg tcttcgacgc
     4741 ggttttcccg gaactgtgcg tcgcggatat gcatctcgcc cccggagccg ccgcccaggg
     4801 ccaggccgcc ggcaacagca ctgatctcgg cctggacctc agggccagtg cgcccatgtt
     4861 ttccgccgga caattccaca tcaccaacgc cacggcatcc gccagaatta ccggcccgca
     4921 ccggcccgag tacgatctgc gcatccgggc tctgacggag ggcgaacctg cggaattcgc
     4981 ggcgcgcgtt ctcatggacg gccccgccat tcttctgcgt aacgccacac tgagcctgcc
     5041 ccagaacaaa ctgacggtta caggcactct gaacacggac agcaacatat ttcagggtca
     5101 tggccatctt gacagcgcaa gtctcgctcc tctgggccga ctggccgggc aggatatgga
     5161 cggaaagctc acgctgtgca cggattttct tgaggagaaa aaccggcagg ccgtccgcat
     5221 cgaaggaaac ggcaatgccc tgtccatggc cgggatacat atcggccacg cggccctgca
     5281 cggctccacg gctctgcccg atcctctgcg gagtgcggac gcggacctgc ggctcgggca
     5341 tatccaccgg gattctctgc atctggacgc ctgccggata caggcgcgga gccgcaatga
     5401 cggcgtgcat ctcgtcttcg ggctggacca gaacgccacc cagagcgcga tcactggaaa
     5461 ggccctcgcc tcctgggatg aaagaaggct tcgggcctcc ctgaactccc ttgtgggcac
     5521 gttgctgggt caaaagctcc ggctggccgc acccgtgaac atcaccgtgg agtcggagcg
     5581 taccgcctgg accagaggcg agttgcattt cggaccggcg gttctgtccg gttcgggaaa
     5641 catcgccgca aatggcgtgg acatcgatgc cagccttgaa aacatggacc cggccctgtt
     5701 ccggttgctg cgggatgatc tgccccaggg agatatccag gcgcggctgg ccgtccgggg
     5761 ggctccggaa aatccggatg ccaggatgga tgtgcggggg cggaacatcc gcatatccgc
     5821 tcccggccgg aaagaccccc tcacggtgga tgtttcggga catgcgaccc tgaacccggg
     5881 ccggttcagg agcactttga ctctgaatgg acaggacggt gcgatgaccg cagacgcgga
     5941 actttccgtt cccgtgcgag gtcccgtgac cgctcttgat atcgccggtg acgcacccct
     6001 cacgggacgc atgcggggcg gcctcgacct caccctgttg ccgcatctgc tgctgctcga
     6061 tgatcagtcg ctttccggcc gggcagtcat ggacttccgc ctcggaggga ccgcatccac
     6121 ccccaccttg agcggtacgg cacacgtcgg cgacgggcgc tacgaaaatt accgctccgg
     6181 caccagactc gaatccatca gcgccaccgc cacggcccga gacgcagagg tagatttcat
     6241 tctgaacgct acggatggcc gccaaggcac gctcagtgcc cagggttcgg cagacctgaa
     6301 gcccctttcc tatgtctgcg atattcgcct ggaccggtgc gagctcgtca acacggacct
     6361 gatccgcagc acggcggatg gccgtctgcg cgtgtgggga aacggcgggg cggcggccgt
     6421 aaacggcact ctgaaaccag acccggctta cgtccagctg ccctccgaca tgtccggcgt
     6481 aacccgcgtc gaagtagagg aaatcaacgt tccgggcgga gatacgagca gcggaaaaga
     6541 ctccggcatg cccgtgaacc tgaacctgcg ggtcgacgtg cccacccggc tcttcgtccg
     6601 gggccggggg ctggattcgg agtggtccgg gcggctggac atcaccggtc cgcagacggc
     6661 tccgtcggtc agggggcaga tgaacctgct gcgcggccgc ttcgagtttc tcgatcgcat
     6721 gttcgacctg accaagggaa ccatctcctt aagcggagaa accccgccca atccgtttct
     6781 ggacattctg ggcgaatgcc gggtcatgga taccctgatt caggtccgga tcaacggtcc
     6841 ggccagaaat ttcaaactgg ccctgtcctc cgccccgccg ctgccacagg acgagttgct
     6901 gtccatgatt ctcttcggcc gttccctgcg cgagatatcc ccgctgcaag ccgtccgtct
     6961 ggcccaggct gcggccgccc tgaccggagt cggaggagcg gggatgggtg tcttcgattc
     7021 catcaaggcc gctctggggc tgcaggaagt ggatatcggc agggatgacg aaggcaatac
     7081 ggccgtcggc atcggcggct atgtgggcgg aaaatattat gtgcggaccc aaagcagcgt
     7141 ctccgggcag gacaggacga aaatcgagat tcagctttct ccgaaaatca gtgtggagac
     7201 ggaaatcggc tcggactccc gtcagggtgg cggtgtgaac tggcgcaagg actattgacg
     7261 ggcggaatgt tctggcccgg aattgtcaac cagcgcaaaa aaacataccg ggtgcggaca
     7321 cgtgacgagt tcggacggaa agctcctgcc cggagccgcc cgagattgcc cggaaccact
     7381 gcgcatctgc acgattcgta agcggattcg ggacacgcca taagaacctt ccaacccgga
     7441 cacaaatcgg cggaaacgtg cacgtcctca ccatggcgcc ccttcttccc tcctggacag
     7501 gaagcttttc cggacgtttt tttcccggta ccaattttat cgacgcctcc ttcgatttcg
     7561 attttctgaa cgatctgcct tctctgtacg cgaacctgcg ccactggctg tccagcatgg
     7621 acagcgtcgt agcggtatat atcggcattc tggtcctcat cgtactgatc atcctgtacg
     7681 caatacagac tcacagaacc agagttcagg ctttgcgcct gtcgcttctg gtgcataacg
     7741 ctccggtcat gatccgcgca cacgacaaac gcggcgtccc cctgttctgg aacagggaat
     7801 gcgaacgcgt caccggctat ccggcccgca gaatcgtgaa caattccgac tcctggaccc
     7861 tgctctatcc cgaccccgcg ctgcgggaca aaacagcggc catgcggaaa gcgcccgcac
     7921 gcgactatac cgacgcccgc aatcccgtca cctgcgcgga tggcagcacc cgcatcatca
     7981 cctggttcag catttccgaa agccatccca ttccgggctg gtactcctgg gaaacgggtc
     8041 tggatatcac cgagcaacag gccgccgccg aggccttaaa ggaacgcgac ctgcgtcaga
     8101 aagccattct ggacaatatc ccggacgtgg cctggctcaa ggacagaaag ctccgtctgg
     8161 tcgccgtgaa caggcgtttc tgcaccctga tgcaaaggac cgaacatgcg ctgctcgggc
     8221 ggaccatcat ggatttctgg cccgcggaat tcagcgggcc atgtgcggag acggatcgtc
     8281 tggtactgcg tgaaggccgg ccgctgtggc aggaagaacg gattccgtcc tcttcttccg
     8341 aagaaatctg gcacgaaacc ttccgcactc ccatctacgg cacctccggg gaaatcatcg
     8401 gcatcgccgg cataggccgg gacatcaccg aaaaaagaaa gacggcccag gagctgctcc
     8461 tggccaagca gagagccgaa gaagccaaca agaccaaaag cgaatttctg gccaacatga
     8521 gccacgaaat ccgcacgccg ctgaacggca ttctgggtat gctccagctc atgacatcca
     8581 ccgctatgac cgaagagcag agcacctaca tccgtacggc catcacttct tcccggcgcc
     8641 tgtccaggct tctggcggat attctggata tttccaagat agaggcggga cagctcgaga
     8701 tcatccgcga acccttcgcc atacgcgaac tccaggaagc ccttcaggac atttttcagc
     8761 tcacggcaaa ccggacgggc gtgcccctgc gcgtacgcat cgctgaagat gtgccgccct
     8821 acctgatggg agacgaggcc cggctgcgcc agatcatttt caatctggtc ggcaacgcgt
     8881 tcaaattcac cacccggggc tctgtcagcg tggatatcga ctgcctgcgc aaaaccacgg
     8941 aacactgccg cctgctgatc accgtgacgg atacgggagc cggcattccg ggctccatgc
     9001 aggacaagat tttcgattcc ttcacccagg tcgagggcag tgcgtccaga agtcatgctg
     9061 gcgtcgggct cggactggcc attgtccggc ggctgataca tctcatgaac gcgaatctgg
     9121 ccatttccag cgctccgggg gaaggtacgg aaatatgcat ttccctgccc ttggacatcg
     9181 cgcgtcacta cgagcagcgc gcggaagcgg aaaaagccat acagacttct tccagccccc
     9241 tgagatttct ggtggccgag gacgaccaga tcaatcaact ggccatcacc cggcttctgg
     9301 aaaagaaggg gcaccgggtg cactgtgtgg ccaacggcct gacccttctg gaggaagtca
     9361 aatcgggcgc ctacgacatg gtgctcatgg acgtgcagat gccgggcatg gacggtatcg
     9421 aggccacccg gcacatccgt ctgctgcccg agttcgagcg cgtacggacc atccccatca
     9481 ttgcgctgac cgcctgcgcc atgagcggcg accgggagag attcctgaga agcggcatgg
     9541 acggctatat tccaaagccc gtggactgga acatactgag tcacgtcatc gccgtcgtgg
     9601 cggaaaagcg ccgggcccgg aacgtcagag atcttccccg gccgagggca tgacaccctg
     9661 cgtcagcgcg gctatttcct gcagggcgcg cccccggtcc tgagccagct gcttccactt
     9721 cttcttttcc ttctttgtgg cttccagagt ctgaagcagg tcctgaatgg tatgcgccgg
     9781 atagccgtac ttggcgtgcc tgcccttgcg cagttcctcg tcgttgcgct ccttcagcgc
     9841 cctgatctgg ctggaggaaa gaatcatggc gttttcggcg gctttccggc agcgctgttc
     9901 cgccggagtt tggtgggtgc ggacatggga ttctctcgaa atgcggataa aaacaaaggc
     9961 ggagatgcga acaaagaggg cggtttcaaa ccgccctttc ctattttttc agccaggcca
    10021 tcatgctgcg cagttcgtca ccgacccgct ccacctgatg ctggtggctg cggcggcgct
    10081 tggccagaaa cgacggcagc ccggccttgt tttccagaat ccagttccgg gcgaaggtgc
    10141 cgtcctgaat ttcctccagc acggcgcgca tggccttgcg ggactcggcg ttgatgacgc
    10201 gcggcccggt gacgtaatcg ccgtattcgg ccgtgtcgct gatggaatga tgcatcttct
    10261 tgaacccgcc ctcatacagc agatccacga tgagtttgag ctcgtgcatg cactcgaaaa
    10321 aggcgatttc cggctggtat ccggcctgta ccagggtttc gaatccggcc cggaccagct
    10381 cgctgacgcc gccgcacagg accgcctgct cgccgaacag atccgtctcg gtttcttcgg
    10441 cgaaagaggt ctcgagcacg ccggaacggg tgccgccgat gcctgcggcg taagccaggg
    10501 ccttggccag tgcctggccc gtggcgtcct ggtgaacggc gaccaggcag ggcacgccgc
    10561 cgcccttctc gaactcgcgg cgcaccaggt gccccggccc cttgggcgcg atcatgacca
    10621 catccacatc tttgggcgga acaatctggt tgtaatggat gttgaagccg tgtccgaaga
    10681 ccagggtttt gcccgcggac aggttgggca gaatttcttc ctcgtatact ttgggctgat
    10741 actgatcctg caccagaatc tgaatcaggt ccgccttttt ggccgcttca gccgcggtga
    10801 cgggttcgaa gccgtgctcc cgggccagct gccagttggc cccgcccgga cgctggccga
    10861 ccaccacccg cactccggaa tcgcgcaggt tctgggcgtg ggcgtgacct tggctgccat
    10921 agccgatgat ggccaccacc ttgtccttga gtgtgttcag gtccgcgtcc ttttcgtaat
    10981 acactttcat gactgctccc ttgtcgtaat gaaaacgggc ggtccggccg cgcaacatgc
    11041 cgcccgcccg aaaaaatatt gccggcacaa ttcccgcgcc gggatatcag tccgcaagct
    11101 gcatgctgcg gcgcatggcc acggtcccgg cgcgcacgaa atccttcact ccgaagcgtt
    11161 gcagcagcgc gaccacagcc ttgatcttgt tccggtcccc cgtcagttcc agagtcagct
    11221 ccgtggggct gacatccacc accttgcacc ggaaaatatc ggcgatacgc agcacctccg
    11281 cgcgcttggc gtcgtcggct ccgactttca tcagcacgat ctcccgctcc acggcctgct
    11341 ggtgggtcag atccacaacc ttaatcacgg tgatgagctt gtgcagctgc ttcatgatct
    11401 gctcgatgat ctgttcgtcg ccgatggtac agatggtgat gtgcgaaacg cccggctcca
    11461 gggtcggccc cacgttcagt gattcgatat tgaatccccg gccgctgaaa agacccgcca
    11521 cgcgggacag tacgcccggc tcgttctcca ccagaatgga cagcacatgt ctcacgcgag
    11581 cctcctaaac caaaagcatt tccgccaggg ccgctccggc cggcaccatg ggcgcgacat
    11641 tttcctcggg ctccacgcgc acgtcgacca ccaccggacc gggatgggca aaggccgccc
    11701 gcagggtgga ctccagctct tcggactttt ccaccagaaa gccctcggct ccgtatgctc
    11761 tggccagagc cacaaaatcc ggattggcgt gcagacaggt ggagcagtag ttcttcttgt
    11821 aaaaaagctc ctgccactgc cggaccatgc ccagatagcc gttgttcaga atgacgatct
    11881 tgaccggcac ttgatagctg accgccgtgg ccagctcctg gatgttcatc tggatggagc
    11941 cgtcaccggc cacatccacc accagcctgt cgggaaaggc cagctgcgcg ccgatggccg
    12001 ccgggaatcc gtagcccatg gttccgagcc cgcccgacgt gagcagagtg cgcggcttgc
    12061 ggtatgtgta gaactgtgcg gcccacatct ggttctggcc cacttcggtg gtgatgatgg
    12121 cctcgccccg agaaatctcg aaaatctttt ccaccacctg ctgcggtttg atccgctccc
    12181 cagtctttcc gtagcccagg ggatgaacgg cgcgcatttc cgccagggcg gcgttccatt
    12241 tttcgtgctt ggcggcccag tccacgccgg aaatcctgtc cgcttcctcg atgagcccct
    12301 gaagccccag cttgcagtcg gccacgacgg gcacgtgcac caccacgttc ttgctgatgg
    12361 acgtgggatc gatgtcgata tggatgatcc tggctccggc ggcgaaggcg ctgacccggc
    12421 ccgtgacccg gtcgtcaaag cgggcgccca cggaaatgag cacgtcgcag ctgttcacgg
    12481 ccatgttggc cgtataggtg ccgtgcatgc caagcatgcc gagccacagg ggatggtcgc
    12541 cgggaaaagc cccaagcccc atcagcgtgg tggtcaccgg acactgacag agttccgcca
    12601 agcggaccag ttcggcggcg ctgtcggacg agatgacgcc ccctccggcg taaatggccg
    12661 gccgttcggc ctgggcgatg agttcagcgg ccttgcgcag ctgcttgcgg ttggggctgt
    12721 agttgggatt gtagctgcgg atgtggatgg tctcgggata ggaaaattcc gtggacgcgg
    12781 tgatcacgtt cttgggcagg tcgatgagga cggggcccgg ccgccccgtc cttgctatat
    12841 agaaggcctg tttgatggtc gcggccagct ccgccacatt cttcaccaga tagttgtgct
    12901 tggtgcacga acgggtgatg cccacgatat cggcttcctg aaaggcgtcg ttgccgatga
    12961 gatgcgtggg cacctggccg gtgatcacga ccagcggaat ggagtccatg taggccgtgg
    13021 cgataccggt cacggtattg gtcgctccgg gaccggaagt caccaggcat acgcccacct
    13081 tgcccgatgc cctggcatac ccgtcggccg catgcacggc ggcctgttcg tgacggacca
    13141 ggatatgtct gaacggatga ttcgggagct cgtcgtatac gtcgatgacc gcacctccgg
    13201 gaaaaccgaa aatgaggtca acaccttccc gcttcaggca ttccatcagg atccgggcgc
    13261 cggtgagcat catggccgtc tatccctcct ggcgtttata tttttcgagc agtccctgga
    13321 tgcgggtttt cccggccagt ttcttcttct tgtattcctt cacttccagc tcttccgcag
    13381 gggaaagcgc ggcctttcca gagtagcgtt ccagagcctt ttcaaaaccg acatgcgctt
    13441 cccacagagc cctgagttcc tcgtcgtgcg ccagattcgc cgcaatgagt tcgaggtctt
    13501 gctgttccat aggacgtctc cttagttgag gtttgccgta tctccggcgg aaaaaagatt
    13561 ccagtccggc tcctcttcgg cgtgtacgac cagacttttc ttccgggcgc cgtgtccgga
    13621 ttcgatcgtc acctgacgcg gccgcagacc cagagcctcg gccacgaaaa aagtcagcgc
    13681 ggtgttggcc ttgttgtcca ctgccggagc ctggaggcgg attttcacat gttcaccgtg
    13741 catacccgcg aactccgtct tcttcgcccc cggctgcacc cagacggaaa tccgccagcc
    13801 gcctttggcg ggaacgacgc acacgggacg gccggacatg tctttatatc gccatccggg
    13861 ccacaagctg gcccatgaaa acctgtatga acttgatgcc cagcaggacc accaccgggg
    13921 aaaaatccat gccgcccgcg taagagaaag gcaacgcctt gcggacgcgg taaaagaccg
    13981 gctccgtcag agtgcggatg ccccggacaa tggggttgta cggatcggga ttgatccagc
    14041 tcatggccgc cgacaccagc actatccaga agtacaaagt cagcacgctg tccgccacat
    14101 agaaagccgc cgccagcagg ctggaaaaaa caggcatgaa gtctcctttg caatcgatta
    14161 ttggccaacg ctctcaagcc attgccgcag ttcatggaag ctgtccacat ggagttccgc
    14221 ccgcagtccg cgatttttat acgcccagaa gggcactccc gctcccctgg cggcatcctg
    14281 gtccacgctc gaatcgccga gataggccat gtgttccacg ggcattcccc attcttcggc
    14341 aatgcgcagc aacccctcgg gatggggctt gggccgggac accttggccg ccgtcatgac
    14401 cggggagaaa aacccggtca gatgaaaccg ctccagcacc ttctccatgg agttcttgcg
    14461 gttggtgttc acggccatac gcacgcccct tatctggagg gattcgagca ggtccccgag
    14521 ccccggttcc gggatcatgc ggtcgatgaa ctcgtcatag gtcatgtgcc ccacgacctc
    14581 gggcagtctg ggcatgagct ccgccgggac aagacgggcc agggacacat ccaccgtgtg
    14641 catgaaggag tagtcttctt cttcggccgt catgggggca agccccagtt tttcgagaat
    14701 gtggttataa tagaaacggt tcacgtcgcg cgtgtcgaaa agcacgccgt cgcagtcaaa
    14761 gaccagcccc cggaccggcc ggacgccgca tccgggcgaa gacgccgggg tgtcacgtcc
    14821 gggcatggct atttcatggc ctccgggaaa tactgggccg ccagttcgcg caacctgtat
    14881 ttctgaatct tgccgctggc cgtcatcgga tactcgtcga taaaagcaat atatttcggt
    14941 atcttgtacc gggaaatctg cccccggcag aaatcccgga tatcttccac agcatagtcg
    15001 aagccgtcct tcaatatgat gaaagcgccc acttcctcgc cgaacttgcg gctgggcaca
    15061 cccaccacct ggacatcctt gatgccttcc atgcggtaga gaaattcctc gatctcccgt
    15121 ggatagacgt tttccccgcc gcggatgatc atgtccttca gacggccggt gatggtcacg
    15181 tagccgtcct tgtccatggt gccgaggtcg ccggaatgca gccagccgtc ggggtcgatg
    15241 gcctgggcag tggcatcggg gttgttgaaa tatcccttca tcacgttgta gccccggcag
    15301 cagacttccc cctgctcgcc cggaagcatt tcctcgcccg tatcggggtc gaggatgcgc
    15361 acctccactt ccggcatggc ccggcccacg gtctgggtcc gctgagccag ggagtcgtgc
    15421 acccgggtct gggtcatgac cggcgaggcc tcggtcaggc cgtagcagat ggtcacttcc
    15481 cgcatgtgca tggcgtccat gaccttttcc atgaccggca ccggacaggg cgagccggcc
    15541 atgatgcccg tgcgcaggga cgagaggtcg tagcgggcga aggtgcggtg ttcgagcacg
    15601 gcgatgaaca tggtgggcac tccgtacagg gccgtgcatt tttcctcttc cacggcggac
    15661 agcaccagaa gggggctgaa tccttccaga atgaccagcg tggccccgtg cgtgacggcg
    15721 gccagcacgc ccagcacgca gccgaagcag tgaaacagag ggactggcag gcagacccgg
    15781 tccttggagg tgaaacgctg gttttcaccg atccagaaac cgttgttgcc gatgttgtga
    15841 tgggtcagca tgacgccctt gggaaaaccc gtggtgccgg aggtgtactg catgttcacc
    15901 acgtcgtgcg ggtccagact gtcctgccgc ttccggtaat cctcctcgga agtcatgcgg
    15961 ctcagggcca ggagttccgg catggaatac atgccccggt gcttttccgg gccgagaaag
    16021 aaaacccgtt tcaggtcggg aaatttttcg gtgcgcagat agccccgctc ctgtgtcctg
    16081 agttccggca gcaggtcgta gaccacctga atatagtctg tgtcccggaa ggaatcgatg
    16141 accaccagat tctcgcattc ggaatgtctg atcaggtatt ccagttccgc cttcttgtaa
    16201 tgggtgttca ccgtcagcag caccgcgccg accttggccg tggcgaattg cagagccacc
    16261 cagtacggca cgttggtggc ccacacggcc actttctccc ccttgcccac gcccatggcc
    16321 atgagcccct tggccagatt gtccaccagg gcgccgaaat cccggtaggt catgcggaaa
    16381 tcgcgatcca catagaccac ggcctcattc tccggatact gcgcgacggc ctcgtccaga
    16441 atctgcccca gagtcatgtc gcgtaacaca ggcttgtgca tgcttctccc cctgattgcc
    16501 cgctattccg gaaaatacag taccgcgtag atggaagcgg gcgcgtcacc gctacagccc
    16561 acatggtgcg gcacaacgga gttgagatag atggagtccc ctttggagag aatgatggtc
    16621 tcgccgccat agatgacctc caccgcgccc tcctgcacca cgatgaactc ctcgccctcg
    16681 tgggtggaaa gtttgcgtcc ggcttcggcc acgggcagaa gctccacgaa aaacggttcc
    16741 attctgcggt ccgtcttgcc cctgcccaga gaatagtacc gggtatccgt ggaactgccc
    16801 ttctgggcct gcatggccat atcttccacc cggcccccga ggcgcaccac cagcgggtcc
    16861 tggcccagtt cgtcgtccag aaaggtgccc atgcgcacgc caagaccgcg ggcgacttta
    16921 agaagcggcc ccaaagacgg atatacggag tcttcctcca gggacttcag gaaagaaagg
    16981 gacagaccgg tgcgttcggc cagctgctcc agagtgatct cgttcatctc ccggaagcgc
    17041 ttcacgcgca tgccaagctt ttccttgctc ataaccaccc gctactggtt agggttcaga
    17101 aggccggacc acgatgacgg cggacaggct cgcatcgccg gcaggctcca gatcgtgggg
    17161 agacacgcgc aggtgaatga agtcctcgcc accggcgccc gcttcacggg gcagcccgag
    17221 agagagaagt tctccggcca catccggatc cgaaacgaaa aaccgggttc cctcagggac
    17281 aagacagaga agcggcccga acatgccccg ccagggcaga tcggaacccg cccggggaaa
    17341 aatcagcgcg tcagccacgc cctgatccgc aaacgcatcg ccgtcctcaa ggcccaggga
    17401 tgcggcaaaa cctccctgtg cccgcgccag acggtcttcc tgtccgtgca gggccgcgaa
    17461 ctgctcttcg cgggacaaag ccagagtcag cgcgacctgc gcccgcctgc ggcggtcatc
    17521 ggcggatgcg gcctcgggag ccgccttttc ccgcagcctg gaccggatat ccatgcccgt
    17581 gtccgtgtag aaatcctcca gcccggcggc ttcatagggg cgcaaatccg aaattctgga
    17641 cagtccctgg gcgaaatcca catattcgct cgccagccgc cgcgcgcatg ccccgctcag
    17701 gggcagattt tccggccgcc agcggggaaa ttccgaagcc agttccacgc cgggatcgaa
    17761 cagaacgacg ccctccggca aggggccgtg aatcaggccg ggatgcagcc agggaaaatg
    17821 caccatcatc aagccgttct ccttccgcgt cgtcaacgtt cataccgccg gcaccggccc
    17881 gtacagggcg gcagccgcaa gaggcacaaa tctcccgcaa gcagcgcgca cgaagggccg
    17941 gaagcttcgc cgtctggccg gaaatccggg cattcccagc gttcctcgag gcagaccgcc
    18001 atacgctccc agatgctccc ggcttcctct gcggtgagcc cgaaacattc cgagcgggcc
    18061 acatgttctt ccagaatttt ttcccagccc tcaagcacgg tgcagcggaa attccggcgc
    18121 agaccgggat tgaggtgctc ctcgtacagg cagcgctctc ccatccagtg tctgcaaccc
    18181 cggcccgaca gcctgatcgg gctcgtatgt ccgtttgtga ccatcgcgtt tcagcgtcct
    18241 cgccgcgaag atttcagata cattccatcc gcccgaaaac caagattttt cttcaagttg
    18301 acctcccgaa gtccccgagt gtatagggca ccaaccattc ccgaggaggc aaaacatgtt
    18361 cggcatcggc attccggaac tacttatcat tctggtcatc gtcctgatca ttttcggcgc
    18421 caacaaactg cctgaaatcg gagcgggcat gggcaaggcc atcaagaatt tcaagaaggc
    18481 gaccaacgaa cccgaggaaa tcgacgtcac ggccaaatcc gaaacctccg atacggaaaa
    18541 gaaaagctga ccccggctgg tccgggcgaa tttcaaaggc cgccatgcgg cctttgcttt
    18601 tttggaagtg tgaaaaacgc cgggtaacgc cgatttccga aagcagaatg ccgcaagccc
    18661 gtatctcctc ccaacgcgcc gacccgtcgg cggaaagttc cccggaagcc ctcccttttc
    18721 gcgtgcgcgg gcgtctggcc ccgagcccca cgggacatct gcacctgggt aacgcctggt
    18781 cctttctgct ctgctggctg gccgtcaggg cggccggagg agtcctcgtc ctgcgcatgg
    18841 aagacatcga cccggaccgc tcccgcccgg aatacgcggc ggaaatcatg cgcgatctgg
    18901 actggctggg gcttgactgg gacgaaggtc cgccgggagc tctctacacc cagagcaccc
    18961 gcctcgaacg gtacgccgag gtccttggca cgtttatgcg cgacgggctc gcctatccct
    19021 gctactgtac ccgcaaggag ctgaaatcca tggcctcggc cccgcacgcc gaagacatgg
    19081 ggccggtcta tcccggtaca tgcctgggcc tgaccgatgc ggaacgtcgc ctgcgcgagc
    19141 gggaaggccg ccgggcctgc ctgcgcctgc acggcggaga agatacacgg ttcaccgatc
    19201 tggcacgcgg gccggcgcat ttcgggtggg cggaatgcgg cggagatttc cccctgcgcc
    19261 gttcggacgg cgtcatctcc tatcagctgg ccgcggccgt ggatgacgcg gaccagcgga
    19321 tcacgctggt cgtacgcggc cgggacattc tgcccagcac gccccggcag atgctcattc
    19381 tccgcctgat gaaggccccc cttccccggt acgcccacgt gccccttctg cttgaccatg
    19441 agggcgaacg tctggccaaa cgccaccagg ccctgaccct gaaaagcctg cgggaagccg
    19501 gaatccgccc cgaagccgtg acgggttatc tggcctgccg ggccgggctg ctgccccgcc
    19561 ccgggtccct ctccccgctc cagctggttc cctttttctc ctgggaccgg ctgccccgcc
    19621 atgacgtgcg tctggaaccg gatatgctgc ccagactgcg cggcctccgg cttgccaccg
    19681 ccccttgcgc ccgatagagc ggcgtggcgg aagccacggc tccgcgggtc aaaacgccgc
    19741 gtggcactcc aaccggcgca tcacgccgac tacggccgtc ccgcacgcaa cgcctcaacc
    19801 ggacatcttt cgaggaaaga tcatgatcga caaaggaata agccgcgtct ggctccagca
    19861 ttacgacaag gaagtctcgg ccaatctgag ctacgaacat atcagcatgt acgagatact
    19921 ggcccgcgcg gctgaacgcc atcccgaacg cacggccctg atcttcaaca actggcgcgt
    19981 aagctacaga aagctcaagg ttctggtgga tctgaccggc accaacctga gaagatccgg
    20041 cgtccggccc ggcgaccggg tagccatcat gctccccaac tgtccccagg ccgtcatcag
    20101 ctattgggcc tgtctccggc tcggagccgt ggtggtcatg accaaccccc tgtacatgga
    20161 aaaggagctg gttcatcact tcaacgattc cggggccgcc accctcatca ccctcgatct
    20221 gctctggaat cgcatagaca gcctgcgccc gcgtctgggg ctcgaacgca tcttcatcac
    20281 gtccatatcc gactgtctgc gcttcccgct gaatctgctc tacatgttca aatcccggcg
    20341 tgaacaccgg ctgcccgaca ttccttacgg ctcttccggc gttgcatcct ggaaaagcct
    20401 gctcgcgcgc acggccgtgg agccgcccca tcctattgat ccgcagaaag atctggccct
    20461 gctgcaatac accggcggca ccaccggcgt atccaagggc gtgatgctga cccacgccaa
    20521 tctcttgtgc aacgcgagac agtgccaggc tgtgctgcac ggcatctcgg aagagcggga
    20581 aaccggacag gtcatcctgg gcctgctgcc gttctttcat atttacggcc tgacggtgtg
    20641 cgtcaatttt ggcatgctca tcggcgcgac cctcattccc gtgcccaaat tcacccccgc
    20701 ggacgtgctg aagaccatca gcaaaaagcg cccgaccatc ttcccctgcg ctccgtccat
    20761 attcgtggcc ctgctccagc agaagaatct ggcccgctac gacctgtcct cggtgcgcta
    20821 ctgtatttcc ggctcggccc ccatgcccgt cccggtcatg gaaaaattca acaaactgac
    20881 cggggcgcgc atcgtggagg ggtacggact gaccgaagcc tcgcccatca cgcacctgaa
    20941 tccgctgctc ggggtgaaca agaacggctc catcggcctg ccctttcccg atacggacgc
    21001 ggccattgtg gatatggacg tgggctccgt gcccctgcct ccgggcaaga tcggcgaact
    21061 tgtcatccgc ggcccccagg tcatgggcgg ttattggaac cggcccgatg aaacggcatc
    21121 cgtgctcaga aacggctggc tctacaccgg cgacatcgcc tacatggacg aagagggcta
    21181 tttcttcatc gtggaccgca agaaagatct catcatcacc gggggataca acgtctatcc
    21241 gcgggaaatc gacgaggtcc tgcacgagca cccggccgtc aaggaagccg tgagcgtggg
    21301 catcaaccac cggaccagag gagaaatcat caaggcctat atcgtgctgc gggaaggata
    21361 caccctgacc aaggccgaag tgctggcctt ctgccgggaa aaactggcca attacaaggt
    21421 gcccaaacag gtggagttcc gggacgagct gcccaaatcc attgtgggca aggtcctgcg
    21481 ccgggtcatc cgcgaagaag aggaacgccg gggcgatcac gacggagact gtgacgacga
    21541 actcaccggc gatggttttg aaatgaaaga aaatcagcgc ggacaggagg atgagagcat
    21601 ttagagcatc tcaactttga aatgcggcag cgtgatccgc tgccgtaacc gcgaaacaaa
    21661 tcccgcgccc tgaaattgtc cttgggagga cttttttaga tagtgccgtc aaattatttc
    21721 tgcccacaat gagatacacc tgatttgcac ggcggcaagg aaggagaggc ttcgttttgc
    21781 ataacacgtg gcgatgccac gccatctctt gaggtgaaga aaggcgttcc cgaccaggtg
    21841 ccgtacacgg tacagttctc tgtcatagtc gcgctgttcc ctgcgatttt ttctgggcgg
    21901 gatgacggac tggcagccgg actcaacagc cttgtctgta agttcattgc tgtcatatcc
    21961 gcgaccaggc aaaagcatct ccgcgctcaa gccatcaatc aatgcacacg cttccttgca
    22021 atcagctctg gtaccttctg taacaacaac tctgagcggc atgccatgcg catccacggc
    22081 cagatgtatt ttggtgttga gccccctttt gtacggctca tcgcctagtt gccgccaacc
    22141 gctccggcag catggggatg ccccggaaga ggtcaaaatc cggcatatct ccaattgcct
    22201 gaaggccgac cctgcctatg gcaaaggcgt cgccgacgct ctcggcatcg acctggcccg
    22261 ggcgcccaga taacctgaac tgaccccgaa cctgcagact ccggtcatac tgcagcatga
    22321 ccggagtcct gcgggtctta tgcaatcccc gaactctgcg ggcacctgcc ggagggcctc
    22381 agaatttccc tcacccctcc ataaaggccg ccaccactta ctttccgaac tggcacttgg
    22441 ggtatgtgca tactttgcag gccagacaaa aaccgccttc gcccatgcgg gagagttccg
    22501 cgcgggtgat ttcccgcccg gccagcatac gcggcagcac aagatccaga aatgtcgtct
    22561 tgaaatagag cgcgcaggcg ggcacaccga gaacctgcat ccagccgtcg cggccgggaa
    22621 gcctgcccat gaggctcatg gccccgggca gtaccggaac gccgtgcagc acatccgtca
    22681 gtccggcctc gagcagagcc tgccgggtga cgtcgtcggg gtccacagac agtcctcccg
    22741 tggttaccag caggtccgcg cccgcctcac ggatgtccgc aaccgccgag gcgatagcct
    22801 cccggtcgtc gggggcgatg acggatttga ccaccgtgca gcggtactgc ctggccttgg
    22861 ccgtgatcac gggaatgaac ctgtcctcaa tgacgccctg aaacacttcg gtgccggtca
    22921 ccagaatgcc caccttggcc tgtcgcagcg gcaacacgcg aaagagaggt tcactgccga
    22981 gcacatgcag cgcctccccc agacgttcgg aactgatatg aagcggtatg gcccgcgtgc
    23041 cagccagctt gtcgcccttg gagaccaccg ctccatcctg gcgcgaggcc gccatgatct
    23101 cgggaatcat gttgaaacat cgcatccgct ccacatcgac gcagaacagg ccgtcgatac
    23161 cggccataaa atcgatcttt ccttcgtgcg gaggcagact gtaggtcacc cccagtccgg
    23221 ccatgcgccg ggcgaactgt tccgccgcct cgttctcgtg caccagtcct tcc
//
