LOCUS       NZ_HG529332.1          16320 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HG529332.1 Faecalimicrobium dakarense strain FF1, whole genome
            shotgun sequence.
ACCESSION   NZ_HG529332
VERSION     NZ_HG529332.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:16:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16320
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16320
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3950:6320](-)"
                     /cutoff="2000"
                     /detection_rule="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /neighbourhood="10000"
                     /product="Hydroxy-L-proline2proline"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3951..6320)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /neighbourhood="10000"
                     /product="Hydroxy-L-proline2proline"
                     /protocluster_number="1"
     cand_cluster    1..16320
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_proline or cds(PFL-like and
                     Gly_radical)) and Radical_SAM and P5CR_dimer and
                     F420_oxidored)"
                     /kind="single"
                     /product="Hydroxy-L-proline2proline"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16320
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Hydroxy-L-proline2proline"
                     /region_number="1"
                     /rules="((PFL_proline or cds(PFL-like and Gly_radical)) and
                     Radical_SAM and P5CR_dimer and F420_oxidored)"
                     /tool="gutsmash"
     CDS             complement(3..101)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MEIDKNKLTPMMKQYFEVKDRYPDCILFFRLGD"
     CDS             complement(319..1044)
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MKKLDGFQLKIIALVLMLMDHLYFAFPTVFPEWFHPLSRIVAPIF
                     AYLMVEGFFHTRNRFKYNLRLCGWALFMEVGNRLLNIILASKEVGTHNNIFMTLALGLT
                     VLNLIELAKKNNGIKKIGLIVATLLLLTLTIFVEGGMAVIPFILITYLFRENMKKTVIG
                     YTVLSLILFKINFMWYGDIKETLNMLMFNSDFLLILAVPFILAYNGERGLNNKFSKYLF
                     YVFYPLHLWGLAVLQFILK"
     CDS             complement(1183..1974)
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MDHYLFIVEGAHDVALISSILRVLKFRCIKDINKVTKPFNNLLID
                     RFPYEKNSLENYNKIPSFYDKGNQSVCIISADGETKLIKALDNAISKFRLDELDEITKV
                     VIFCDGDLKIREDKISELIKISFPKDNDLEINKNKLIDGFLSLNNVDIINIETEFFVMP
                     NNKDSGRLEQILIEAIKSVDKALLEEVDLFLSNIPNKYKSKWGESNSRYDKTRISCVGN
                     VKNPASSMGLLIGSSKWITSDTVKSCKLLGGIYKYIEETIK"
     CDS             complement(1974..3047)
                     /locus_tag="ctg103_4"
                     /transl_table=11
                     /translation="MPLNIILYKCFEEGYVLPNHIKDIYIQSFKGIKDLKLEDMKSINI
                     LVGDNNSKKTTVLEAVELFERPYDFISHIKRVSRKYNLKTVKYNKIKEMFYNCDLDNEI
                     NINLYIKDKLNRLCINGKEEQLICIDDNGQTNELKDFDRTILRYEFNNESREFIMSDNQ
                     KSFIRPKKQLELLNIGYMMPIDTYMEDSSIEAIDRVIKNGEKQRLIDMLKIFDDNIVDI
                     NFTSDREIYITTNDKLSMSMGSFGDGFKKAIILTSKVIDSENGILLVDEIETGIHKDII
                     GKIFKEIIKNSKLYNTQIIATTHSLEAIGALLEKFDESLNEVAIYRLEEFKGQIYSRRF
                     SGDKAYEIVVQEGGDLR"
     CDS             complement(3118..3924)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) P5CR_dimer"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:NADP oxidoreductase coenzyme F420-dependent
                     (Score: 71.7; E-value: 1.9e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_5"
                     /sec_met_domain="F420_oxidored (E-value: 6.2e-23, bitscore:
                     71.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="P5CR_dimer (E-value: 2.3e-43, bitscore:
                     137.2, seeds: 951, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKSIGFIGSGNMAKAMIGGIVKSGLVNSENIISSDLNEKTLKSI
                     KNEFNINTTTKSDEVVKNSDIVIVAVKPNIYDVVLESVKDFIDSDKIIVTIAAGKTISS
                     IENVIGKDKKIIRTMPNTPALVNEGMSAICPNKNIIDEELEIVKSIFSSFGKAEVVNEY
                     LIDSVIGVSGSSPAYVFMFIEAMADAAVLNGMPRNQAYKFAAQAVMGSAKMVLETGIHP
                     GELKDMVCSPGGTTIEAVKTLENKGFRSCVIDAVTDCIKKSKEMSE"
     CDS             complement(3951..6320)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: PFL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Hydroxy-L-proline2proline: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_6"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-34, bitscore:
                     109.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 1.3e-230, bitscore:
                     757.8, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRGNFDRTKKLRKQSVNGVPHITIERARLITDAYKKYEGSVETP
                     VLRALAFKHYMENRTLCINDGELIVGEKGDCPQGAPTYPELCCHTLEDLDIMNQREIIS
                     FKVDSNVKKIQEEEIIPYWENRQIRKRIMDSMNKEWLECYESGIFTEFMEQRAPGHTVG
                     GGSFYKKGFLDFKKEIKYEIDKLDFINDLDAYDKKSQLEAMDIACDALIIYGKRYADYA
                     RELADKEIDENKKKELLLIAKNCDIVPANKPQTFHQAVQMYWFIHVGVTTELNIWDAFS
                     PGRLDQHLNPFYENDIEEGTLDEDKAKEILECLWIKFNNQPAPPKVGITLKESGTYTDF
                     ANINTGGVTEDGKDGINDVSYLILDVMDEMKLLQPSSNVQISRKTPERFLKRACEVSRK
                     GWGQPAFYNTEAILQELIEAGKSIEDARHGGTSGCVETGCFGKEAYILTGYMNLPKILE
                     ITLNNGIDPMSGKKIGIETGDARNFKSYQDLFEALKAQLHHFVDIKVNGNNIIERIYSK
                     HMPAPLMSVIVDDCIKKGKDYNAGGARYNTKYIQGVGIGTITDSLSSIKYNIFDKAKFT
                     MDELLTALENNFEGNELIYNLVSNKTPKYGNDDDYADELMQQVFNAFYNDVTGRKSPIG
                     GTYRINMLPTTCHVYFGEVMKASANGRLSQKPLSEGISPEKGADTNGPTAVIKSCSKMD
                     HIKTGGTLLNQRFAPSVVEGEDGLDNMANLVRAYFNMDGHHIQFNVFDKNVLLRAQENP
                     DEYKDLIVRVAGYSDHFNNLSRALQDEIINRTEQVF"
     CDS             complement(6326..7237)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_7"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-21, bitscore:
                     67.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNPLIINIQKCSIHDGPGIRTTVFFKGCPLECAWCHNPESQSYA
                     KEVLYNEEKCSRCETCIKKCPNDAIYTQENNVYLEKNKCKLCETCLDYCINNAREMVGT
                     TYKVKELAKEIEKDMMFYEQSNGGVTLSGGEVMAQDIDYIKSIVLACKNKGISVAIDTC
                     GYAKFDNYEKILSYVDLFLYDIKLIDDEKHKKFTGKSNNLVLDNLKKLSEKNANINVRI
                     PLIEGVNVDEGNTEVLKIIEFLKDTNVKEVNLLPYHNIGMHKYKKLYRDYEGLEFKKPD
                     DKKLEEIRSLFELNNFKIKIGG"
     CDS             complement(7251..7811)
                     /locus_tag="ctg103_8"
                     /transl_table=11
                     /translation="LKEDIGLKIKQLRTSKNMTLKDLSEKTNLSIGFLSQLERGLTSIA
                     TDTLQTIAEVFDVELSYFFLKPRVKNKQVVRSYEKEVYNICTFGCIQYNLSNNLDDKQM
                     LPRLVEILPNNTEEDIQPYSHEGEEFIYILEGTLTLFLDEKEYELYPGDSVHFSSLQHH
                     NWANYTNKMVKILVTSTPNPYKK"
     CDS             complement(7970..10384)
                     /locus_tag="ctg103_9"
                     /transl_table=11
                     /translation="MNSIINNIVKSNLKENKLRSIMVMIAVVLTTTLLTSVGIITLTMM
                     QNQKERTIEGYGNAHAYYRKLEEEQVEKLKAHKDVEIFGINGSQIGKFELDESLFGFGY
                     VDENALDLSNKSIIKGTFPTKSNEVLIDKKGLKKLGYSDEVGQTIKIKFHDINKNYTEK
                     DFIVSGIIPLDEGSEANNAHMIIVSKKFMKENNYKTSLRANIRIKNEDKLSRVELEEKI
                     NEVASSLGFKEENTVLNSMYLLWMKPNPTTVLCAVVVCLVIMFSAILVIYNIFYISIIN
                     RIQDFGKLKAIGCTKKQLKQIIIKEGMILSIIAIPLGITLGYIISSLILNNILGLIGEK
                     ATNLSIKTNSSIIIGSAILTLLTVYISLLKPSKIAAKISPVEAMKYIESNNDSKKKNRK
                     GYIDIDVLKLTKANLYRNKKRTLITVLSLSLSGMLIIAASTVMMSINTEQMVKYGLAGD
                     FSFGHKYIGYDFEKEKADFINNNPLNQDFINNIKNIDGVERIDEIREIKVTTPNIGGEM
                     KKVEPELKDVEIDLDGYTDDMLKLAGSDLTSGKFNLEKIKSGEEVLINGSAEHWNGFKV
                     GDIITLTVNEDNKKVDKKVRVQGRTKYHLGGEVITSIDFITNPKYITSISISVDKNKEE
                     SIGKALTNISNEYKKLNYSSYKERLENYEKSFMSTNMMGYSLITIIGVISLVNLINTMI
                     TSILSRKKEIGILQAIGMSDKQLLKMLKLEGVFYTISTLVFSLIFGSAIGYLGYKVMYN
                     TGAEYMIYKFPIVPGLIVVVVMVLVQFVIGYIINKIFNKESLIDRVRYSEN"
     CDS             complement(10377..11060)
                     /locus_tag="ctg103_10"
                     /transl_table=11
                     /translation="MKVLETKSLKKYYGKDENIVKAIDNTSIEINQGEFVAIVGKSGSG
                     KSTLLHMLGGLDRPTSGNVYIDNKDIFSLNDDKLSVFRRRKIGFIFQYYNLIQSLNVWE
                     NIVLPIGLDGRKVDIDFVNDVIKTLGLEDKKESLPNTLSGGQQQRVAIARALAARPAII
                     LADEPTGNLDSKTSDEVMMLLKNMVKKYSQTLVIITHDESIAQMADRVIHIEDGKVIKG
                     GAINE"
     CDS             complement(11124..11960)
                     /locus_tag="ctg103_11"
                     /transl_table=11
                     /translation="MIDNISDYIDNFIKNNYKVEEKLEEDGIFMSLISRTKDLGKKLDI
                     ELNKLNNEKENLKSLITDISHQLKTPLASISLYNSILLEDDISKEDRKTFVIQNEESTK
                     KLHNLIDSLVNISRLESSMIKINPECINIKNTIIKAVKSVYIKAINKNIEINLDEFEDL
                     KVNHDKKWTEEAIFNVLDNAIKYTEDNGNIDIKISQTISYLRIDIKDNGIGINKEELNN
                     LFKRFYRGKEAKDIEGSGVGLYLSRKIVEAQGGSIVASKNIDKGSTFSLLLQKCNN"
     CDS             complement(12026..12367)
                     /locus_tag="ctg103_12"
                     /transl_table=11
                     /translation="MIKSLKQDPLLKSTVVKISLLFLLLTLVLNVFHISQLDALYKEQI
                     NLTRSMVGKLVTYYPKDEANIVNVLKEGNEDLENRGKSVLNKYGYKDNSILKDNKSKVI
                     IYKSIIVFF"
     CDS             complement(12364..13059)
                     /locus_tag="ctg103_13"
                     /transl_table=11
                     /translation="MKNILVLEDDESLNNGISFMLKREGYNVFSTFNIQQAKEFFYNNN
                     INLIISDINLPDGDGLSFCEEIRKISDVFIIFLTALDEEVNIVNGYNIGGDDYITKPFS
                     LIVLISKVNAFMKRINKEESKFKYIVSDEITFYLEELKIIKNNEELILTKNEYKLLKYM
                     MENSQQILTKDQLLECIWECDGQFVYDNAVAVNIKRLRDKVEDDIKSPTYIKNVRGIGY
                     TWAKGCVRK"
     CDS             13242..13577
                     /locus_tag="ctg103_14"
                     /transl_table=11
                     /translation="MKKENYFRKLQKLIWIDIGIFTVVYIIGTIILEIFNIPINSIWAW
                     LILGGIPIFLVISVYTKLMKFPYECQSCQKVFNIKFRDMFTLHAGDSRRLKCPYCHKTT
                     WAKIKID"
     CDS             13596..14129
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_15"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.4e-19,
                     bitscore: 60.2, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEILLKNDKKAIIRKANTKDAQEIINYLNKIGGESDFLTFGENE
                     FNMSLENEEKYINSHEDTNNSIMIVTLVDGKIVSVASITSVQKDRLKHVGSLGISVFSE
                     YWGLGIANEVMTYLINWAKSNSITKKVTLSVREDNYKAINLYKKFGFEEEGNFKSDIFI
                     NDIYYNTISMGLLV"
     CDS             complement(14189..15415)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_16"
                     /sec_met_domain="Peptidase_M20 (E-value: 2.6e-09, bitscore:
                     27.4, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNFNVDTKELNLEEVKNDLIKIIDENKEIYIYASHAIHSNPEIG
                     NKEYFACETLSNLLKENGFEVETNIAGHVTGFIARKKSKTNIGKTIGFLAEYDALPGIG
                     HACGHNIIGVASCAAAIALSQEIDEIGGEVIVFGCPSEEGGENGSAKGSFVKANVFDNV
                     DACLMIHPSNETSVTGNSLAVDPIDFEFIGKPAHAAACPEKGINALDGVIQLFNGINAL
                     RQHVPDDVRIHGIITHGGDAPNIVPEYAKARFYIRAQTRKTLNEVTNKIKSIANGAALS
                     TGASVNIKFFQNQVDNFYVNNKFNELFVSVINELGHEICTERQNGFGSTDAGNVSHVVP
                     TLHPHIKIGPSSLVGHTEEFCKASASKEGDEALIIGAKSLSLTALKLLVDGEVFKEIKE
                     EFENNKYLL"
     CDS             complement(15441..16253)
                     /locus_tag="ctg103_17"
                     /transl_table=11
                     /translation="MKKIFTLLLTIIISIGSLVGCSNTSNDDNKTVKLGVTGEEHEIWD
                     LVKEKLAKEDINLEIISFSDYIRPNLALSEGEIDLNAFQHHAYLENFNAERKLDLVSIG
                     DTVFAPMAIYPGKLKSLDEIKEKSTIAVPNDATNLGRALILLQSVGLIKLKEDVGLLPT
                     LKDIVENTKNIEIKELVATQIPRSLQDIDVAVINSGVAVNAKLSPTEDALFIEDSSLEI
                     SKPYINLIAARSKDKDNEVYKKVVKAYQSQEIKDAINKLFKGESIPAF"
ORIGIN
        1 aaatctccta atctgaaaaa taatatacaa tctggatatc tatctttaac ttcaaagtat
       61 tgtttcatca taggagttaa tttattttta tctatttcca ttagctttac ctccctcatt
      121 tctgttgttt gtaatctatt gtaaaatttt tattatgtat aattttatat agtttatttt
      181 ctattagtct gattaattat tataccataa ctgaaaacta ttattaagag tgtatattaa
      241 atacttaata gttatcttgt tttatataac ttccttatat aaaaaataaa ggatgaagct
      301 atactatagc ttcatccttt attttaatat aaactgcaat acagctaatc cccataggtg
      361 tagtgggtaa aatacataaa atagatattt tgaaaactta ttattaagtc ctctttctcc
      421 attataagct aatataaatg gtactgctaa tataagtaag aaatctgaat taaacattaa
      481 catatttaat gtttctttaa tatctccata ccacataaaa tttatcttaa ataatataag
      541 tgataaaact gtataaccaa taactgtttt tttcatattt tctctaaata aatatgttat
      601 tagtataaat ggtatcacag ccattccgcc ttctacaaat attgttaatg tcagtagtaa
      661 taaagtagct actattaatc ctatcttttt aattccatta ttcttcttag ctaattctat
      721 taaattaagt actgtaagac ctaatgctaa agtcataaat atattattat gagtacctac
      781 ttctttagaa gctaaaatta tgtttaaaag tctatttcca acttccataa ataaagccca
      841 tccacaaagt cttaaattat atttaaacct atttctagta tggaaaaatc cttctaccat
      901 taaataagca aatattggtg caactattct tgataatgga tgaaaccatt ctggaaatac
      961 tgttgggaat gcaaaataca aatggtccat cagcattaat acaagtgcta taatttttaa
     1021 ttgaaatccg tctaattttt tcatattgtc tccttatctc ctatgatttt atgctttaat
     1081 tatataatca tagtataaaa gaagacattt aattgcatta cactgtactt acatttttgt
     1141 aagattaaga aatatttcaa taaaaaatga cctaaattta ggtcatttaa ttgtttcttc
     1201 tatatattta tatatccctc caagtagttt acagcttttt accgtatctg atgttatcca
     1261 tttgctactt cctattaata atcccattga tgaagctgga tttttaacat ttccaacaca
     1321 agatattcta gttttatcat atcttgagtt actttctccc catttacttt tatatttatt
     1381 aggaatatta gataggaata aatccacctc ttctaataaa gctttatcta ctgattttat
     1441 tgcttctatt aatatttgtt ctaaccttcc gctatcttta ttatttggca taacaaaaaa
     1501 ctcagtttct atatttataa tatctacatt atttaatgac aaaaaaccat caattaactt
     1561 atttttgttt atttctaaat cattgtcctt tgggaagcta atctttatta actcacttat
     1621 cttatcttct ctaatcttaa ggtcaccatc acaaaaaatt actactttag taatctcatc
     1681 tagttcatct aacctaaact tgcttatagc attatctaat gctttaatta atttcgtttc
     1741 tccatctgca cttattatac atacactttg atttccttta tcataaaaac taggtatctt
     1801 attataattt tctaaactat ttttttcgta tggaaatctg tctattaata aattattaaa
     1861 aggttttgtt actttattaa tatcttttat acatctaaac tttaataccc taagtatact
     1921 tgatattaat gcaacatcat gagccccttc tactataaaa aggtaatgat ccattatctt
     1981 aaatcaccac cttcttgtac tacgatttca taggccttat ctcctgaaaa tctccttgaa
     2041 tatatttgac ctttgaattc ttccagccta tatatagcta cttcatttag actttcatca
     2101 aatttttcaa gtagagctcc gattgcctct aaactatgag tagttgctat tatctgagtg
     2161 ttatataact tactattttt tattatttct ttaaaaattt ttcctattat gtctttatgt
     2221 attcctgttt ctatttcatc tactaataat attccatttt cagaatctat aactttagaa
     2281 gtaagtatta tagctttttt aaatccatca ccaaaactac ccatactcat acttaattta
     2341 tcattagtag ttatatatat ttctctatca gatgtaaagt ttatatctac tatattatca
     2401 tcaaatattt ttagcatatc tattaatctt tgtttttctc cattttttat aactctatct
     2461 attgcttcta tagaactatc ttccatatat gtatctattg gcatcatata tcctatattt
     2521 aaaagctcta attgcttttt aggccttata aagctttttt ggttatcact cataataaat
     2581 tctctagatt cattattaaa ttcatatcta agtattgttc tatcaaaatc ttttagttca
     2641 ttagtttgac cattatcatc aatacatata agttgttctt cttttccatt tatgcataat
     2701 ctatttaatt tatcttttat atataaattt atgttaattt cattgtctaa gtcacagtta
     2761 taaaacattt cctttatttt attatatttg acagttttta gattgtattt tctgctaact
     2821 ctttttatgt gagatataaa atcatagggt ctttcaaata actcaacagc ttcaagtaca
     2881 gtagtttttt tagaattatt atctccaact aatatattta ttgatttcat atcttctaat
     2941 tttaaatctt ttatcccctt aaaactttgt atataaatat cttttatatg gtttggcaat
     3001 acatatccct cctcaaaaca cttatataaa attatattca ggggcataaa aataagacta
     3061 gtataatata tatctagtct tattttagtt aagtatttag ttattagtta tatatattta
     3121 ttcactcatc tctttcgatt tcttaataca gtctgttaca gcgtctatta cacaacttct
     3181 aaacccttta ttttctagtg ttttaacagc ttctattgta gttcctccag gagagcatac
     3241 catatccttt aactctcctg gatgaatacc tgtttcaagt accatttttg cagatcccat
     3301 tactgcctga gctgcaaatt tataagcttg atttctcggc attccattaa gtactgcagc
     3361 atctgccata gcttctataa acataaatac atatgcaggt gaagatccac taacacctat
     3421 cacagaatct attaaatatt catttactac ttcagctttt ccaaatgagc taaatataga
     3481 tttaactatt tctagttctt catctattat atttttattt gggcatatag cgctcatacc
     3541 ttcatttact aaagcaggcg tatttggcat agttcttatt atttttttat ctttacctat
     3601 aacattttca atagaagata tagtttttcc agctgctata gttactataa ttttatcact
     3661 atctataaaa tcttttacgc tttctaaaac aacatcgtat atattaggtt taactgcaac
     3721 tattactata tcactatttt taacaacctc atctgacttt gtagttgtat ttatattaaa
     3781 ctcattttta atgctcttta gcgttttttc atttaaatct gatgaaatta tattttcaga
     3841 attaactaat cctgatttaa ctattccacc tatcattgct tttgccatat ttccagaacc
     3901 tataaaacca atgcttttat tcattttatc aatctccttt tggcatttta ttagaaaact
     3961 tgctcagttc tatttattat ctcatcttgt aatgctctac ttaagttatt aaaatggtca
     4021 ctataccctg caactcttac tattaagtcc ttgtattcat caggattttc ttgagctctt
     4081 agtaaaacat ttttatcaaa tacattaaat tgtatatgat gtccatccat attaaagtat
     4141 gctctaacta agttagccat attatcaagt ccatcttctc cttctacaac ggatggagca
     4201 aatctttgat taagtagtgt tccacctgtt tttatatgat ccattttaga acatgatttt
     4261 attactgctg taggcccatt tgtatcagcc cctttttctg gtgatatacc ttctgataat
     4321 ggtttttgtg aaagccttcc atttgcacta gctttcataa cctctccaaa atatacatga
     4381 catgtagtag gtaacatgtt tattctatat gttccaccta taggagattt tctacctgtt
     4441 acatcattat agaatgcatt aaatacttgt tgcattaatt catcagcata gtcatcatcg
     4501 tttccatatt taggtgtttt gttagacact aaattataaa ttaattcatt accttcaaaa
     4561 ttattttcaa gtgcagttaa aagttcatcc atagtaaatt tagctttatc aaatatatta
     4621 tatttaatag aagataaact atctgttatt gtacctatac caacaccttg aatatacttt
     4681 gtattgtatc ttgctccacc agcattataa tcttttcctt ttttaataca atcatcaact
     4741 ataacactca taagtggagc aggcatgtgc tttgaatata ttctttctat tatattattt
     4801 ccatttacct ttatatcaac aaagtgatgt aattgagctt ttaaagcttc aaataaatct
     4861 tggtagcttt taaaatttct tgcatctcct gtttctattc caattttttt accgctcatt
     4921 ggatctatac cattatttaa agttatctca agtattttag gtaaattcat atatcctgta
     4981 agtatatatg cctctttccc aaagcatcca gtttcaacac atccactagt accaccatgt
     5041 ctagcatctt ctatactttt acctgcttct ataagttctt gcagtattgc ctctgtatta
     5101 taaaacgctg gttgacccca tccttttcta gatacctcac aagctctctt taagaatctt
     5161 tccggagttt ttctgcttat ttgaacattt gagctcggtt gtaataactt catttcatcc
     5221 attacatcta atataagata acttacatca tttataccat ctttaccatc ttcagttact
     5281 ccaccggtat ttatatttgc aaaatctgta taagttccac tctcttttaa tgttatccct
     5341 accttaggtg gtgctggttg gttattaaat ttaatccata agcattctaa aatttctttt
     5401 gctttgtctt catctaatgt accttcttca atatcatttt cataaaaagg atttaagtgc
     5461 tgatctagtc ttcctggact aaaggcatcc catatattta attcagttgt aactccaaca
     5521 tgtataaacc aatacatttg tactgcttgg tggaaagttt gtggtttatt ggctggaaca
     5581 atatcacaat ttttcgctat taataataat tctttcttct tattttcatc aatttcttta
     5641 tctgctagtt ctctagcata atcagcatat cgttttccat atataattaa agcatcacaa
     5701 gctatatcca ttgcctctag ctgtgatttt ttatcgtatg catctaagtc atttataaag
     5761 tctagcttat ctatttcata tttaatctct ttcttaaaat ctaaaaatcc ttttttgtaa
     5821 aagctacctc caccaacagt gtgaccagga gctctttgtt ccataaattc tgtgaaaatc
     5881 ccactttcat agcactctaa ccattcttta ttcatagagt ccattattct ctttcttatt
     5941 tgacgatttt cccagtatgg tattatctct tcttcttgaa tttttttaac attactatcc
     6001 actttaaaag atattatttc tctttgattc attatatcta agtcttctaa agtatggcaa
     6061 catagctctg gataagttgg tgccccttgc gggcagtccc ctttttctcc tacaataagt
     6121 tctccatcat ttatacataa agttctattt tccatataat gcttaaaagc taaagctcta
     6181 agaactggcg tttcaacact tccttcatat tttttataag catcagttat aagacgagct
     6241 ctttcaatag ttatatgagg tactccattt acactttgtt ttcttagttt tttagttcta
     6301 tcaaaattac ctctatccat tttgattatc cccctatttt aattttaaag ttatttaatt
     6361 caaataaaga cctaatttct tctaactttt tatcatctgg ctttttaaac tctaatcctt
     6421 cataatccct ataaagcttt ttatatttat gcattcctat attatgataa ggtagaagat
     6481 tgacttcttt tacattagta tcttttaaga actctataat ctttaatact tctgtattgc
     6541 cttcatctac atttacacct tctattaaag gtattctcac atttatattt gcattttttt
     6601 cacttaattt tttcaagtta tctaagacta agttgttact ttttcctgta aacttcttat
     6661 gcttttcatc atcaataagt tttatatcat ataaaaataa gtctacataa gaaagtattt
     6721 tttcataatt atcaaattta gcatagccac aagtatctat tgctacactt atacctttat
     6781 ttttgcaagc taatacaata ctttttatgt aatctatatc ttgagccatt acctctcctc
     6841 cagacaaggt aactcctccg ttagattgtt cataaaacat catatccttt tcaatttctt
     6901 ttgctagttc tttaacttta taagtagttc ctaccatttc tctagcatta tttatacaat
     6961 aatctaaaca agtttcacaa agtttacact tatttttttc caaatacaca ttgttttctt
     7021 gtgtgtatat agcatcgttt ggacactttt taatacaagt ctcacatcgg ctacattttt
     7081 cttcattgta aagaacttct tttgcgtaag attgactttc tgggttatgg caccaagcac
     7141 attctagagg acatccctta aaaaacacag ttgttcttat acctggtcca tcatgtatac
     7201 tacatttttg tatattaatt attaatggat tattcataat atcacctata ttatttttta
     7261 tatggatttg gagtggatgt tactaaaatt tttaccattt tatttgtata atttgcccaa
     7321 ttgtgatgtt gtagggaact aaaatgtaca ctatcccctg gataaagttc atactctttt
     7381 tcatctaaaa ataaagttaa tgttccttca agtatataga taaattcttc tccctcatga
     7441 ctataaggct gtatatcctc ttctgtatta tttggtaata tctctaccag cctaggaagc
     7501 atttgtttat catctagatt atttgataaa ttgtattgta tacatccaaa agtgcatata
     7561 ttatacactt ctttttcata gcttctcaca acttgcttat tttttactct tggttttaag
     7621 aaaaaataag ataattctac atcaaatacc tcagctatgg tttgtaaagt atctgtagca
     7681 atacttgtta atcctctttc taattgagat aaaaatccta ttgataagtt tgttttttca
     7741 cttaaatctt ttaatgtcat atttttactt gttcttaatt gttttatttt taaacctata
     7801 tcctctttca atttgatcct cctattttca cttatactat aaatatacta ttcacagtat
     7861 aatatttcca ctatttttta tatatttatg aatttttttt agtattagta aactaattta
     7921 tttagtataa aaaatagtac tacattaatg cagtactatt ttttatattt taattttcac
     7981 tatatcttac tctatctatt aatgattctt tattaaatat tttatttatt atatatccta
     8041 taacaaattg aactaatacc ataactacta caactattaa gcctggaact atcgggaatt
     8101 tataaatcat atattcagca cctgtgttat acattacttt atatccaaga tatcctatag
     8161 cacttccaaa tattaatgaa aatactaaag ttgatattgt ataaaataca ccttctaatt
     8221 taagcatttt taaaagttgt ttatcactca taccaattgc ttgaagtata cctatttctt
     8281 tttttctaga taatatactt gttatcattg tatttataag atttactaaa cttataactc
     8341 ctataatagt tataagggaa tatcccatca tattagttga cataaatgat ttttcataat
     8401 tttctaatcg ctctttatat gaagaataat ttaatttttt atattcattt gatatattag
     8461 ttaaagcttt acctatagat tcttctttat ttttatctac actaattgat attgaagtta
     8521 tatactttgg atttgttata aagtctatgc ttgtaataac ttctcctcct aaatgatact
     8581 ttgttcttcc ttgaactctt acttttttgt ccactttttt attatcttca ttcacagtta
     8641 aagttattat atctcctacc ttaaatccat tccaatgttc tgctgatcca tttattaaaa
     8701 cttcttcccc actttttatt ttttctaagt taaatttacc agaagttaaa tcactacctg
     8761 caagttttaa catatcatca gtataaccat ctaaatctat ttctacgtct ttaagttctg
     8821 gctctacctt tttcatttct ccacctatat tcggagtagt tactttaatt tctcttattt
     8881 catcaattcg ctctacacca tctatatttt ttatattatt tataaagtct tgatttaatg
     8941 gattgttatt tataaagtca gctttttctt tttcaaaatc atatccaata tatttatgtc
     9001 caaatgaaaa atcacctgcc aatccatact taaccatttg ctctgtgttg atactcatca
     9061 taactgttga tgctgcgatt ataagcattc cacttaatga aagtgatagt actgttatta
     9121 atgtacgctt tttatttcta tataaatttg ccttagtaag ttttaataca tctatatcta
     9181 tatagccctt tctatttttc ttcttgctat cattgttact ttcaatgtat ttcatagctt
     9241 caactggtga tatttttgcg gctattttac ttggttttaa taatgatata tatacagtta
     9301 ataatgtaag tattgctgag cctattatta ttgaagaatt agtcttaata cttaaatttg
     9361 ttgctttttc tccaattaat cctaatatat tatttaatat taagctactt attatatatc
     9421 ctaatgtgat tcctaatgga attgcaatta tagataaaat cataccttct tttataataa
     9481 tttgtttcag ttgtttttta gtgcaaccta ttgcttttaa ttttccaaag tcttgtattc
     9541 tatttattat tgatatatag aatatattat aaattacaag tattgcagaa aacataatta
     9601 ccaaacatac tactactgca cataatacag ttgttggatt tggtttcatc cataataaat
     9661 acatactatt taaaactgtg ttttcttctt taaagcctag gctacttgct acttcattta
     9721 ttttttcttc taattcaact cttgataatt tatcttcatt ttttattctt atattcgctc
     9781 ttagacttgt tttataatta ttttctttca taaatttttt agaaactatt atcatgtgag
     9841 cattatttgc ctctgaccct tcatctaaag gtataatccc acttactata aaatcttttt
     9901 ctgtatagtt tttatttata tcatggaatt taatctttat agtttgtcct acttcatcac
     9961 tatatcctaa ttttttaaga ccttttttat caattaatac ttcatttgat tttgttggaa
    10021 atgttccttt tataatagat ttgttcgaaa ggtcaagtgc attttcatct acatacccaa
    10081 atccaaataa agattcatca agctcaaatt ttccaatctg acttccattt attccaaata
    10141 tttctacatc tttatgtgct tttaattttt ctacttgttc ttcttctagt tttctataat
    10201 atgcatgtgc atttccgtac ccttctatag ttctttcttt ctgattttgc atcatagtta
    10261 aagttattat cccaactgat gtaagtaatg tggtcgtaag tactactgct atcattacca
    10321 ttatacttct taatttattt tcctttaaat tgctttttac tatgttatta atgatactat
    10381 tcatttatag caccaccttt tataacctta ccatcttcta tatgaataac tctatctgcc
    10441 atttgagcta tgctttcatc atgagttata ataactaatg tttgagaata ttttttaacc
    10501 atatttttaa gtaacatcat aacttcatca ctagtttttg aatctaagtt acctgttggc
    10561 tcatctgcaa gtattattgc tggccttgct gctagtgccc tagctatcgc aactctttgc
    10621 tgttggccac ctgataatgt atttggtaag ctttcttttt tatcttcaag ccctaaagtt
    10681 tttataacat catttacaaa atctatgtca acttttcttc catcaagccc aataggtaat
    10741 actatatttt cccaaacatt taaactttgt attaaattat aatattgaaa tataaatcct
    10801 attttccttc ttctaaatac acttaattta tcatcattta atgaaaatat atctttatta
    10861 tctatatata catttccact agttggtcta tctagacctc ctaacatatg tagtagcgta
    10921 ctttttccac ttcctgattt acctactatt gcaacgaatt caccttgatt tatttctatt
    10981 gaagtattat ctattgcctt tactatattt tcatcttttc cataatattt ttttaaactt
    11041 ttagtttcta gtactttcat tttcttatcc tccctgtttg ttataactat ataataagag
    11101 attagtcttt cagcataatg tcattaatta ttgcattttt gcaataatag ggagaatgta
    11161 cttcctttat ctatattttt actagctact attgaacctc cttgagcttc tactattttt
    11221 ctacttaagt ataatccaac tccagagcct tcaatatctt tagcttcttt ccctctataa
    11281 aatcttttga ataaattatt tagttcttct ttatttattc ctatcccatt atcttttata
    11341 tctattctta aataacttat agtttgagat atttttatat ctatatttcc attatcctct
    11401 gtatacttta tagcattatc tagtacatta aatatagctt cctctgtcca ttttttatca
    11461 tgatttactt ttaaatcttc aaattcatct aagtttattt ctatattttt atttattgct
    11521 tttatataaa cactcttaac tgcttttata atagtatttt ttatgtttat acactctgga
    11581 tttattttta tcatactcga ttctagcctt gatatgttaa ctaatgagtc tataagatta
    11641 tgtaattttt ttgtactttc ttcattttga attacaaagg tctttctatc ttcttttgat
    11701 atatcatcct ctaaaagtat tgaattatac aagcttatcg atgctagtgg cgtttttaat
    11761 tggtgtgata tatctgttat taatgatttt aaattctctt tttcattatt taatttatta
    11821 agttctatat ctagtttttt acctaaatct ttcgttctag atattaaact cataaatatt
    11881 ccatcttctt cgagtttttc ttctacttta tagttatttt ttataaaatt atcaatataa
    11941 tcagatatat tatctatcat ttttattaat gatttaaaga gtttactaag tagtatcaaa
    12001 ctaagtatta atgctattag tgatactaaa aaaacactat tatagactta taaattatta
    12061 ctttactttt attatcttta agtatgctat tatctttata tccatattta tttagcacac
    12121 ttttacccct gttttctaaa tcttcattac cttcttttaa tacattcact atatttgctt
    12181 catcttttgg gtaatatgtc acaagttttc ctaccataga tcttgttaaa tttatttgtt
    12241 ctttgtaaag agcatctagt tgacttatat gaaatacatt taaaactaat gtaagtaata
    12301 aaaatagtaa actaattttt actaccgtac tttttaataa tgggtcttgc tttagagatt
    12361 ttatcatttt ctaacacatc cttttgccca tgtatatcca attcctctta cattctttat
    12421 ataagttgga ctttttatat catcttcaac tttatccctt aaccttttta tatttacagc
    12481 tactgcatta tcatatacaa attgaccatc acattcccat atacattcaa gtaattggtc
    12541 ttttgttaat atttgctgac tattttccat catatattta agtagcttat attcattttt
    12601 agtaagtatt aactcttcat tatttttaat tatctttaac tcttctaaat aaaatgttat
    12661 ttcatctgat actatatact taaattttga ttcttcttta tttattcttt tcataaatgc
    12721 atttactttt gatattaaca ctattaagct aaaaggcttt gttatataat catcccctcc
    12781 aatgttatat ccatttacta tgtttacttc ttcatcaaga gcagtcaaaa atattataaa
    12841 tacatcactt atttttctta tttcttcaca aaatgatagc ccatccccat caggtaaatt
    12901 tatatctgat attattaaat ttatattatt gttataaaaa aattcttttg cttgttgtat
    12961 attaaatgta gaaaatacat tatacccttc tctttttaac ataaaactta taccgttgtt
    13021 taaagattca tcgtcctcta atactaatat atttttcata tccccctcca aaattttatt
    13081 tattgtcatt tttaattata cttaataaac tctagaaaaa ctatctaata tatgcctttt
    13141 aaaattcata agttattatt tctaacccta tatttaattt cttgcaaata ctttacttta
    13201 tatatacaat tactttaata gcgtatgaag ggattggttt tatgaaaaag gaaaattatt
    13261 ttagaaaact tcaaaagctt atttggatag atattggaat atttacagtg gtttatataa
    13321 tagggactat aatacttgaa atatttaata ttccaattaa tagtatttgg gcatggctaa
    13381 ttttaggtgg catacctatt tttttagtta ttagcgtata tactaagcta atgaaatttc
    13441 cttatgaatg tcaaagctgc caaaaagttt ttaatattaa atttagagat atgtttactt
    13501 tacatgctgg tgatagtaga agacttaaat gtccatattg tcataaaact acttgggcta
    13561 agattaaaat agattaattt atagggggat aaattatgaa agagatttta ttaaaaaatg
    13621 ataagaaagc tataataaga aaagctaata caaaagatgc tcaagaaata attaactatc
    13681 ttaataaaat tggtggtgaa agtgattttt taacttttgg agaaaatgaa tttaatatga
    13741 gtttagaaaa tgaagaaaaa tatataaatt ctcatgaaga tacaaataat tctataatga
    13801 tagttacctt ggttgacgga aaaattgtaa gtgtcgcttc aattacttca gttcaaaagg
    13861 atagacttaa acatgttggt tctcttggga ttagtgtatt tagtgaatac tggggacttg
    13921 gcattgctaa tgaagttatg acttatctaa taaattgggc taaatctaat agtataacta
    13981 aaaaagtaac tttatcggtt agagaagata attataaagc tattaattta tataaaaaat
    14041 ttggatttga ggaagaaggt aattttaaaa gtgatatttt tataaatgat atttactata
    14101 acactattag tatgggacta ttagtttaga ttaattgaaa aatttaaatt taagactatg
    14161 atttttgtat catagccttt tatattattt ataataaata tttattattt tcaaattctt
    14221 cttttatttc tttaaaaact tcaccgtcaa ctaaaagttt taaggctgta agagataaag
    14281 attttgctcc aattattaaa gcttcatctc cttcttttga tgctgatgct ttgcaaaact
    14341 cctctgtatg acctactaaa ctagacggac ctatttttat atgtggatga agcgttggta
    14401 ctacatggct tacatttcca gcatctgtag aaccaaatcc attttgtctt tcagtgcaga
    14461 tttcatgacc tagctcattt ataacactaa cgaaaagttc attaaattta ttgtttacat
    14521 aaaaattgtc cacttgattt tggaaaaatt ttatattaac actggctcct gtacttaatg
    14581 ccgctccatt agctattgat tttattttgt tagtcacttc atttaaagtc tttctagttt
    14641 gtgctcttat ataaaatctg gcttttgcat attcaggtac tatatttggt gcatcacctc
    14701 catgtgttat tattccatgt attctaacat catcaggtac atgttgacga agtgcattta
    14761 ttccattaaa aagttgaatt actccatcaa gtgcatttat tcctttttca gggcaagctg
    14821 ctgcatgtgc tggttttcct ataaattcaa aatctatagg gtcaactgct aagctatttc
    14881 ctgtaactga agtttcattt gatggatgta tcattaaaca agcatcaaca ttatcaaata
    14941 cattagcttt tacaaagctt cctttagcac tgccattttc tccaccttct tcagatgggc
    15001 atccaaatac gattacttct ccgccaattt catcaatttc ttgagataat gctattgctg
    15061 ctgcacaact agctactcca attatattat gtccacaagc gtgaccaata cctggcaaag
    15121 catcatactc tgctaaaaat ccaatagttt tacctatatt ggttttggat tttttcctcg
    15181 ctataaatcc agtaacatga cctgcaatat tagtttctac ctcaaaccca ttttctttta
    15241 gtaaattaga aagtgtttca caagcgaaat attctttatt tcctatctca ggattgctat
    15301 gaatagcatg acttgcatat atatatattt ctttattctc gtctattatc tttattaaat
    15361 cattttttac ttcttctaaa tttaattctt ttgtatctac attgaaattt cccatattat
    15421 ttccccctta tttttattta ttaaaatgct ggtatagatt ctcccttaaa taatttattt
    15481 atagcatctt ttatttcttg tgactggtaa gcctttacta cctttttata aacttcattg
    15541 tccttatctt tacttcttgc tgcaattaaa tttatatatg gctttgatat ttctaagctt
    15601 gaatcttcaa taaataaagc atcctctgtt ggtgacaatt tagcatttac agctactcca
    15661 ctatttataa ctgctacatc aatatcttga agagatctcg gtatttgagt tgctactaat
    15721 tcttttattt caatattttt agtgttttca actatatctt taagagttgg aagtaaacct
    15781 acatcttctt ttaattttat taatcctaca ctttgaagaa gtattaaagc tcttcctaaa
    15841 tttgtagcat catttggaac tgcaattgtt gatttttctt taatttcatc aagcgatttt
    15901 aatttcccag gatatattgc cattggcgca aatactgtgt cacctattga tactaaatct
    15961 aattttcttt ctgcattaaa gttttctaaa taagcatgat gttgaaaagc atttaaatca
    16021 atctcacctt cagaaagtgc tagattaggt cttatataat cagagaaact aataatttct
    16081 aagttaatat cttctttggc taatttttct tttactaaat cccatatttc atgttcttca
    16141 cccgtaactc ctagttttac agttttgtta tcatcattag atgtattact acatcctact
    16201 aaactaccta ttgatattat tattgttaaa agtaatgtaa atattttttt cataataaaa
    16261 ttcccccttt aaattaatga ctaagttttt taagtagtaa atctccaaat ccttgaacaa
//
