LOCUS       NC_014833.1            23953 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014833.1 Ruminococcus albus 7 = DSM 20455, complete sequence.
ACCESSION   NC_014833
VERSION     NC_014833.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:55:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 548154
            Orig. end    :: 572107
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23953
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[558154:562107]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13953
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23953
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23953
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1419..4481)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_492"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 3.4e-11, bitscore:
                     41.5, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFKKLVSGLTSAALSLLMLSGIGVPNANGVLTAKAATANWKFDF
                     GTGGTASGYTGVSASDEYASWRGYGFAQTGNVGNVSAGGNGAGSDAVEFKSDSGSNTFN
                     VDLPKGLYEVKVTVGNAPRCCIKMEGMFQMMNLTGLNASETVKLPVTDGQLNIQAVTGI
                     SNGQRSISAVEITQINTTGVMPKTVWICGDSTVANYYNRSSTQAHGWGQYFGTYASQHG
                     FEVRNMATSGQYAKGFYDGGQFTPIETYGKSGDIYIISIGINDTNYSNKDEYHSTVSTM
                     TQKAKAKGMDVILVKQQGRHADYNRNPKLSGRWFGGELDSVASEENVRVVDLFNAWQDF
                     GFSIGGYDAMTPYYASGDDLHQSLEGAKKLAELMSGLVFETKEPVQMDTSKMYRFKNVN
                     SGLYLEVKNGEAAVGANVQQWSGAQVGDWNTWRLKHKGYNYYEIWSYLGGGSTYLLDVA
                     NGSSANGANIALNTNQNYGAQWFRFFENGDGSYTMVSRCSGDKGAIEVGSALTYEGANI
                     QQWEVNGHNCQKWILEEVQPNDPEPEPEPEPEPEYTNTLTRYPGDANADGKVDMADAVT
                     IKQYLNNSYRYPLCKQGMKNADVDGNGSINDNDVLYIQQYALGMRSFPAPVYENVSVST
                     DPWDGYYFAVDQTWDDAWAEETNSGFTKTSTDIGKSSNTGYINLNNAVGSSLTFKVTAP
                     TSGKYMAYVRFSNGSSSSRDTKVFVNGNTSSYWIQTFASTGAWTTWDALGLVLPLNAGD
                     NTIKFESAGSDGGPNFDYLTITLTDEPVAELYDPNAQEQYIDNTKPALYLAGDSTCMYY
                     NANKQSQQGGPIQGWGYELPKYFSSNVSIYNHAMAGRSSKKFYDEGRFATIVQNLKKGD
                     FVAIQFAINDAGKSYADRYAPLCGNVDNPSSGSYEWYMTSFIKDTKAKGATPILMSCTL
                     GLKAYKNGRFTGSYTEYADACKKLAAKYSVPYVDVNGAMVNYYNSIGYDNAAKLHIDTT
                     HFNETGAPVIAQLIANAIKSANISGLSNYVK"
     CDS             4883..5380
                     /locus_tag="ctg1_493"
                     /transl_table=11
                     /translation="MYKTGDVVMYGTSGICRVAAVEKRDLTGEEQEYYILRNIYSDKNI
                     YYVPVNNEAALGRMHPVCTKSEVDELISHMNSEGLIWIDNDNKRKEEYSRIIKDADKHE
                     IIRLIKTLYLRRRELSENGRRLRSSDENYLGIAEDMLFEEFAYALGIDRCEVVDYIEKH
                     LA"
     CDS             5609..6238
                     /locus_tag="ctg1_494"
                     /transl_table=11
                     /translation="MKVLILNGSPRVNGNTSIAVNELVKTFEKEGIATEVCHIGNKDIR
                     GCIACGKCSAQGRCVFDDAVNEIAAKFEQADGLVVASPVYYASANATLIACLDRLFYSS
                     HFDKTMKVGASVVVARRGGCSSTFDELNKYFTISGMPVASSTYWNSVHGREAGEAEFDA
                     EGMLTMRSLARNMSFLMKSIALGKEKYGLPDGEPWQPTHFIRDDLK"
     CDS             6253..7008
                     /locus_tag="ctg1_495"
                     /transl_table=11
                     /translation="MAEKIVQTAGRDQLGEFAPDFARFNDDILFGENWNNTDIDLKTRS
                     IITVVALMSQGVTDNSIRYHIMNAKNHGVSQAEMAAVITHTAFYAGWPHAWAVFGIAKE
                     VYADNAPALSEKDRFQKELFFPIGEPNPYGDFFVGQSYLAPVSTEQIPIYNVTFEPGCR
                     NNWHIHHAKNGGGQMLICVGGHGWYQEYGREARPLAPGDIVNIPANVKHWHGAAKDSWF
                     AHLAIEIQGEDSSTEWCEAVNDEDYLKLR"
     CDS             complement(7140..7616)
                     /locus_tag="ctg1_496"
                     /transl_table=11
                     /translation="MERTLRQRIKTIKEIKNQHGMSIPQIQDIVAEHGGYVSPRTMYDI
                     FAEGSEEKNFHYQSIAPIYESLIEVYGDDYTTDDVAALKQMLKERNRQVDDLLIQLESK
                     HDEFEKRLSIYEERKNAYERSISLLEKQLDQLDRLLFDRDRMLQQLLDAYIPNQ"
     CDS             7917..8495
                     /locus_tag="ctg1_497"
                     /transl_table=11
                     /translation="MNMVMIEEKEELLSVKLAERLKKDGFFVVAHGTVLEIMNYIFEVK
                     GTGGQPRHNGLRYELPAEYGEDTLYSYIKMTVSTPLERKVEDMTVDTVLSLGISRALRG
                     YSYLAASITMCVACPDKLYSLNKDVYPEIARKYNVDVSCIERSIRHAICKAYSEDPEPM
                     KKLFRRPIRRPKCQELIAECADIIRRIFY"
     CDS             8731..9849
                     /locus_tag="ctg1_498"
                     /transl_table=11
                     /translation="MNNGITEYFEDIELYEEYDGYFCSIPDIITIAILGSICGLRNIHQ
                     IHQWATNDRVSEFLKEKFGIDHVPCYYWILSLLKYVKPESLNRCFADWVYSFMPEKSKS
                     MTISLDGKTVCSTLKMSKIESPLHIISAQVCELGLTLAQRSTDDKSNEIPAVQELLKEP
                     KIKGNIVVADALNCQKETAEIIVKQKADYLLCVKDNHPNLKKDIEDYVQDSSLRDTMQT
                     VSRTEKNRGRVETRTAYVTTDINWLEQKKEWKNLKCIGAIHTEFSTKKGTSSEWHYYLS
                     SREMTAEQLLHHARMEWSVESMHWLLDVHFEEDWCRVENKDVQQCLNMFRKAAINLIKN
                     FKNRNNSKAAISKLMFECLMEPQMISRVIFEN"
     CDS             10001..11638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_499"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-44, bitscore:
                     148.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMTVSQAMVECLKAEEIKVVYGYPGAAICPFYDALLDAEKDIKH
                     VLVRHEANGGHAASGYARISGKPAVCIATSGPGAVNLITAIATAYADSIPIVCITGQVN
                     TDQIGSDVFQEADVTGAAEPFVKHSYLLKDPADVGRVFKEAFYIAGSGRPGPVLIDVPM
                     DVQKMTVDFKYPKKCDIRSYKPTGKGNALQVKRVTEALRTAEKPLICIGGGVFASNAQA
                     EIVELSEKLNIPVITTMMGISVFSDDDPLYVGMIGTHGTKIANYAVNACDTLFLVGARV
                     GDRAVKTPLELEKDTKILHIDIDPAEIGKNIGADLPLVGDAKMVLRQMLEHIDKHPEGN
                     ADHTAWLKQIEDNRTPTEFAKPVKGTVNPKEFLQKLSERMPADVNICADVGQNQIWTSR
                     YHFKKGGRFLTSGGMGTMGYSLPCAIGAKMADESRVTVAVCGDGGFQMNMMELATAVQY
                     GVDVKVVVFTNTRLGMVRELQTKGYNDRQIAVFLDGSPDFVKLAAAYGIPAIRVTDKKS
                     EDKAIEMLAEEKGMLLCEVVVDKDFPTL"
     CDS             11649..12173
                     /locus_tag="ctg1_500"
                     /transl_table=11
                     /translation="MLHYRILSYGSDYDWGLLVGLISLRDAAEIDRQFEKRLNSLEKEE
                     PFADDMSARLMAELDNSRRTGEYAVITPKGKGCITCLSTSIKFGLMVLDSHKDGQPVIT
                     RTGAVNGRVLEWLSEKGDFTLVLTDNECGALREVLALVGNGMADLEYQGQIYSAYDIKA
                     CMEAVAQLSDS"
     CDS             12365..12862
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_501"
                     /sec_met_domain="ALS_ss_C (E-value: 1.9e-25, bitscore:
                     86.5, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTISVLVENHSGVLSRISGLFSRRGFNIESLAVGPTNDESISR
                     ITIVADGDEHTVEQIEKQLNKLIEVIKVKTFGRDEFVARELMIVKVSAPADKRSEIMTI
                     AEITGAKVMDITLTTMTLEICDRYDRLERFEKVIEPYGILEMARTGTVAVERGAEYFSA
                     KK"
     CDS             12928..13953
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_502"
                     /sec_met_domain="IlvN (E-value: 1.2e-78, bitscore: 260.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.2e-62, bitscore: 205.4,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADAKIYYQQDCDLNVLKGKTVAIIGYGSQGHAHALNLKESGIDV
                     VVGLYAGSKSAEKAKKQGLDVLSVADAVKKADVIMILIPDEKQAALYKSEIAPNLTAGK
                     TLMFAHGFNIHFGCIVPPADVNIVMIAPKGPGHTVRSEYQAGKGVPCLIAVEQDATGNA
                     TEIGLAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQCGFETLVEAGYD
                     PRNAYFECIHEMKLIVDLIYQSGFEGMRYSISNTAEYGDYITGPKIITEDTKKAMKKVL
                     SDIQDGSFAKEFLLDMSDAGSQVHFKAMRKLHAEHPSEKVGTEIRKLYSWNNEEDKLVN
                     N"
     CDS             14156..15310
                     /locus_tag="ctg1_503"
                     /transl_table=11
                     /translation="LNDTLYPIMYIEVNLISILLVLVIGRKTAGLSKMVSHRDFVNAIC
                     AMISFFVSDTVCVTMTGGLLPFVPIVLLLFKAIYFISTSAMCFFWFIYYEHIQDSSFAK
                     SKRSVFAASCLVWAMAVVVIINISNGVLFYIDENNKYCRGSMFNLLYLLSYPYVMITFI
                     RSILAIFRRENYAKRNMLRKLALFPLAPAASGIVQYFRPEIPVACATLSLATLELYLEW
                     TDRMISVDPLTMLGNRKQMEYFYKQWQEDSDSDTMFVMMADANKFKSINDIYGHVEGDA
                     ALVRIANAMRTSCREMNRRANIARFGGDEFVIMVCTDDETVISKLRMRLDECLEQMNTA
                     DNSPYELRICVGVAIAKRSSDLEEIIQQADAKLYEEKARLGHVR"
     CDS             15373..16932
                     /locus_tag="ctg1_504"
                     /transl_table=11
                     /translation="MRYYIYGYTDKGSVKGKNEDAVLVNKEVVKEGFREAVLDAPFITA
                     VCDGVGGENAGDVASELCLQQLSEVVYTSNTDLKQVLMAIHGKIKKRSTLDKASANMQT
                     TLCALAVDEEGKGLCVNVGDSRLYRYVNGTIRQLTTDQSYVQYMYNKGEIDYVDEIEPE
                     YRSAIISAMGSPQSDPQIEQTPLANEFGAEPDDMIIITSDGLSDHVSENEFEVGLSMDL
                     PISEKLVALAKLAILNGSTDNVSIIGIKPFFDFEELAALTRHDAVGKTVNVMEMLEDHN
                     ETEEKDELSDILTIDLDAIIGKGKTQREPEKSYEIASAKVPEPEESEETPIVEAPEPEE
                     PDETPIVEALEPEKPDETPIDEASEPEEPDETPIVEAPEPEEIEETPIVEATEPDEPEE
                     TPIVEASEPDEPDETPIVEASEPDEPDETPIVEAPETEESDETSIVEVPEPEEPEETPI
                     VEAPEPEESEEIHNIKEFEPEEHHDMVSREDIELEAHDLFMQAQASLSRLSGLIPKDNK
                     SE"
     CDS             17138..17326
                     /locus_tag="ctg1_505"
                     /transl_table=11
                     /translation="MAYGDYGTYNGGGGYASQADRHLEVDLKCPNCMGERDIDVNNMYL
                     MYSLCISRRAIAVFFCG"
     CDS             17825..23446
                     /locus_tag="ctg1_506"
                     /transl_table=11
                     /translation="MRKSTHRPQYRLLSGFISLICLFTAVLGSVPSVSAASAELPENIQ
                     LFFNKGEDEVDGVVISNDGKTADYTIEGDKQQVNVTLRLSLNKTYEEGRLQIEVPYDAF
                     TDRRGDPFHLSAKADFLNQLASDSSLLRVKEDRSSTDGVIVLENIKASSPHIDLNLHYT
                     IYANQVVDNSVQDYGIKIFDNETQELRSPEKITATFRTHVRDASVLKYTEDEGVQQGCY
                     YAWDDIIETRYHLSEYGIGEAEFNEMLKEYDFIGYRLKTSVEKNQPVVTYIDDQPGGGE
                     VVAVSKKFNYEDTTPLVKVTEGEYAGQWMFEGAASEYLVLVKYPKTVAEKPDAEGKLPR
                     LRNDVTVTYAGVDGDREDITEDSDYITSVWQTMGAVYSGDIWSVVKKAGPDPTGAVDLL
                     RAGSEAALSYEIEGIGHTYKYGAKDNFTYEDGPYWMEVVDDALYVNGLGEDGRELARLQ
                     PDDFYFKTFTMTVEHKVVEAVTLNLDVKKSHYLPINKRKPVEVYVMTADKPGVWQEDWV
                     LSLPAGNSDYVYADADGNTTFEFKHDKVYRIKFVYRDANGDISLRSNVTGVIRGKGPVV
                     KQVLDNMENNHISDFQVFNWDGQMGYNAAGVWENPTDGRTIYTPNDSVKKDLLALDEEL
                     YAGHSDEEGNVKVTTRLSAKNVLTSIDPFCGLSKKSNGVEQKNKKVYTSYYLAAVTGKA
                     LTEKDLRQLVELGAIKGDKEVVFHELLPMGMSVEEVTPMTETLYLSDRPKEYHWDTLWA
                     RNSGHVKPINTEVPDVSIETIDNYKGTHRQYAKITVKYKDLPVVRLGEQSDICYSLGSV
                     LYLKAVADYEELRSTTLDNYAEAQFIGKDGKPVELAGIMAKSDDGTVFETLKDRDGKQA
                     LEDIDGDNDTKKTTVVADMAVDEVTMYYSATTLKKKIKADDYDLDFKDFTQTYAGHNYT
                     YRLQFFSNEGFAKNVVIYDSIEEAYKEPEFDGMPYWKGTLYGVDISEAEEEFGEVKVFV
                     NTDKFYEEIEMATDTLLGKPGLTPDMLTEDNNWYEIDPDNYDNWENVKTIAFKIGEDVK
                     FGSGEDMPHTVCVYLKMKAPDTIHKDQTKTKQVLAYNAPAYYCEKYIQTKWVKDTTIAN
                     VVTIGLKSAVEKFPAISKTFEGDMPEGFTENCEFDIKPLNGAPAPKAYKDGKWGSAIKT
                     VKVAVNGSETAIADDNGSLFFTEPCVLEYEVSEKAGTRNGVTYSGEKYKVVFNVTDIRK
                     DVQYDDNTELTVDTKIYRTHDENGDELDRPAAVQAVTFTNKYAPIPVKVKIPVISKRIK
                     GSERPEEKQFIFSVQPFTTLGGRADVPAPEKTRAVIKGEGTADFGQVEFTEAGQYDYAI
                     YEVNSAYTGYTFDTRGYLVRFTVTDDDGKLKAAAAPLQVLYPETREYEPAEKAEFVNTY
                     TSKPTDTVAFPDVVKMFSGKERPDDKVFSFTISAKDGKDIPMPENDTVTIEGTGKASFG
                     GVKYDAAGVYVYEIKENDLDDSYSGYTKDKTVYTFTVTVTDNDSILSAETKLTKDGAET
                     ASAEFVNDYSPIVAAVVPPVAVKEIKGNDPDADERIFTFELAAAEGESVPMPEKTTATV
                     KGSGEADAFGTIVYNEPGTYRYVVYEKDLDDSYAGYTKDDAVYTMIVNVRDAGGRYKAV
                     YTLEKNGEKVDELRFVNTYQPAPAEVDLEIEKQIEGTTPDEDETFTFELTAKGGAPLPE
                     NTTANVAGTGKVSFDSWSYTEAGIYVYEVREIEGRNPKYTYDEAVYIVTDTVSDEGGVL
                     TVSRTITDFDGIPSDNVVFINRYDDDWDITREEDSSATPAGGEESSESSEDSSENSSEE
                     ESSSRPEDSSKDSSSKSDSSSSTPNTSNPNTGAKSLVGVEIVMLGALVCVMKKRRNSK"
ORIGIN
        1 tcaactgcac aggcaataac acaggcagaa agaccaatta caacaaggca tctgtacagc
       61 ccataaccaa gcccgcattc tacacaggca cccgccagta cgagggtgag ttctttgatg
      121 tcaagaatgt tgagggctac gttacgaatg cctgcaacag cggcgttaca ggcatacagg
      181 gccatggctt cctgaaatac ggcaagaact acaatgctgc tgtcaaggat accgtacata
      241 ccaataaggc aggtcagttt accatgaagc tgagatattc ttctcagtcg gacatagatc
      301 aggttgatct ctatgtgaac ggcaccaagc aggagaccat gcacctttca aacacctacg
      361 gctactccaa ctggaagaca tatgaaaaga cgatcaacct gaaagcaggg gataacaaga
      421 tcgagttcaa gtcaaattcg gctcttccct cctcgctgta catcgataac tttacagtag
      481 acggcgattt tggtgacggc agcggaacta tcatcgtaaa tgaacccgat cccattcagg
      541 gcaggatcgt aagagacctg aaagttgctg atgccgaaaa cgcagatgat tggtcgatag
      601 tatatgatac cacagtgggt tcaagattct atggcgacag agatatcact gtaagcagta
      661 tcccctctta tctgaaaaac agggaaacta tccgcaccgc ctgcgattcc aagctgtatt
      721 cgggtgacga agctgccttt actgtaaatc agaacgcgac agtatatatc gcagttgacg
      781 atcgtgtaaa tcagggactc agctggctgg gcagctggac caagacctcc gataccatga
      841 ctacatccaa tgatgtagtg cttactttgt tccacaaaga cttttcggca ggcagcagtg
      901 ttacccttgg tactaacggt gcgcagggtc tgtctgcaaa ctatatcgtc tttgtgctcc
      961 ctcagggaac ataccagagc gaaacacatg agtatccaaa agtcacaaat atacagtaca
     1021 atacacagta tcaccagttc aaggtaaact ggtcatccgt caagggcgca tcacagtacg
     1081 gtatagcagt taaacttgcg ggcaggtgga aggtgcaggc ttacaccgat gcttacacca
     1141 ctacattcac atcgcctaag ctgaaggcag gcagttccta tcagatggtt atctgcgcca
     1201 aagtgaacgg caattgggat attactgata tcaattccag atcattctat gttaccgtga
     1261 agtgatctat atccgaacag aaaacggcag cctgccatgg ctgccgtttt cgtataatgc
     1321 ttttactata gaaaagccat agtacttctg aaagcgtatc agaggtacta tggctttgat
     1381 cgttataagc taagtgtttt acatcagatc acttttgctt atttcacata gttgctgagt
     1441 cccgagatgt ttgcggactt tatagcattt gctatcagct gtgcgataac gggagcacct
     1501 gtctcattga agtgagtagt atcaatgtgg agcttagctg cattatcgta gccaatggaa
     1561 ttatagtagt tcaccattgc gccgttaacg tcaacgtaag gaacagaata ttttgcggca
     1621 agcttcttgc aggcatcggc atattctgta taagaacctg tgaaacgtcc gtttttgtaa
     1681 gccttcagac cgagagtgca ggacatgagt atgggagttg caccctttgc cttggtgtcc
     1741 tttatgaatg atgtcatata ccactcgtat gatcctgaag acgggttatc tacgttgccg
     1801 cagagaggtg catatctgtc tgcgtagctc tttcctgcat cgtttatagc gaactgtata
     1861 gctacgaagt cacctttctt gaggttctgt actattgtgg caaatctgcc ttcgtcatag
     1921 aattttttag agcttcttcc tgccatggca tgattgtata tgctcacgtt gcttgagaag
     1981 tattttggca gctcgtaacc ccagccctgg ataggaccgc cctgctgtga ctgtttgtta
     2041 gcgttgtagt acatacaggt agaatctcct gcaagataga gcgcaggttt ggtgttgtcg
     2101 atatactgtt cctgagcatt gggatcataa agctcagcaa ctggttcatc ggtgagtgtg
     2161 atcgtcaggt agtcgaagtt gggaccgccg tctgagcctg cagactcaaa ttttatagtg
     2221 ttatcacctg cgttcagggg cagtacaagt ccgagagcat cccatgttgt ccatgcgcct
     2281 gttgatgcaa atgtctgtat ccagtagctg cttgtattgc cgttgacaaa taccttggta
     2341 tctcttgagg atgatgaacc gttggaaaag cgtacataag ccatgtactt gccgctggta
     2401 ggagctgtta ccttaaatgt aaggctgctg ccgacagcat tgttcaggtt tatataacct
     2461 gtatttgagg acttgcctat atcggtggat gtctttgtga atccgctgtt agtttcctct
     2521 gcccatgcat cgtcccatgt ctggtcaact gcgaaatagt atccatccca cggatcagtg
     2581 gaaactgata cattttcata aaccggagcg gggaagctac gcatacccag tgcgtactgc
     2641 tggatataaa gaacatcgtt atcattgatg cttccgttgc cgtcaacatc agcgttcttc
     2701 atgccctgct tacacagagg atatctgtat gagttgttaa ggtactgttt aatagttact
     2761 gcatcagcca tatccacctt tccgtcagcg tttgcgtcgc cgggatagcg tgtaagcgta
     2821 tttgtatact ctggctcggg ctcaggttca ggctcgggct cgggatcatt tggctgtact
     2881 tcttcgagta tccacttctg gcagttatga ccgttgactt cccactgctg gatgttggcg
     2941 ccttcgtatg tcagtgcgct gccgacttct atcgcgcctt tgtcgcctga gcagcgtgat
     3001 accatggtgt agctgccgtc accgttctcg aagaacctga accactgtgc accgtagttc
     3061 tggtttgtgt tgagggcgat attggcaccg ttggctgaac tgccgtttgc aacatcgaga
     3121 aggtatgtgc tgccgccgcc aaggtatgac catatctcat agtaattata gcccttgtgc
     3181 ttcagtctcc atgtgttcca gtctccgacc tgggcaccgc tccactgctg gacatttgca
     3241 ccgacagcag cttcgccgtt cttaacttcg aggtacagac cgctgttaac gttcttgaaa
     3301 cggtacatct tggaggtatc catctgtacg ggctcttttg tttcaaatac aagacccgac
     3361 atcagctcag cgagcttctt tgcaccctcc agactctggt ggagatcgtc accgctggca
     3421 tagtaaggtg tcatagcatc gtaaccgccg atgctgaatc cgaaatcctg ccatgcattg
     3481 aaaaggtcaa cgactcttac attttcctca gaagcgacag agtcaagctc tccgccgaac
     3541 cagcgtccgc tgagcttcgg gtttctgttg tagtcggcgt gacgtccctg ctgttttaca
     3601 aggataacgt ccattccctt ggctttagcc ttttgagtca tagtagatac tgtgctgtga
     3661 tactcatcct tattggaata gttggtatca tttataccta tggagattat gtagatatct
     3721 cctgatttgc cgtaagtttc aatgggagtg aactgtccgc cgtcatagaa ccccttggcg
     3781 tactgtccgc tggtagccat attccttact tcaaaaccgt gctgtgatgc gtatgttccg
     3841 aaatactgtc cccagccgtg tgcctgggta gaacttctgt tatagtagtt ggcaactgtt
     3901 gagtcaccgc atatccatac tgtcttaggc attacgcccg tggtgtttat ctgcgttatc
     3961 tcaacagcag atatggaacg ctgaccgtta cttatgcctg taacagcttg tatattaagc
     4021 tgtccgtctg taacaggaag ttttacggtc tcggaagcgt tgagccctgt gaggttcatc
     4081 atctggaaca taccttccat tttgatacag cacctaggtg cattacccac agtgaccttt
     4141 acctcgtaaa gtcctttagg aagatcaacg ttgaatgtgt ttgaaccgct gtctgacttg
     4201 aactcgactg cgtcgctgcc tgcgccgttt ccgcctgcgg aaacattacc gacatttcct
     4261 gtctgtgcga agccgtagcc tctccaggaa gcatattcgt cagatgccga tacacctgtg
     4321 taccccgagg ctgtaccgcc cgttccgaag tcgaatttcc agtttgcagt cgcggctttc
     4381 gcagtaagca caccgtttgc attcggtaca ccaatacccg aaagcatcag aagcgacaaa
     4441 gctgctgagg tcagaccgct gaccagcttt ttaaatctca tctaaactcc tccttttctt
     4501 aaacagatgc ccaccttata taaagcatca attttatgat ttaattttaa cacaatttat
     4561 tatcattttc aataatattt tgtgcaaact ttattacata tatgcgacct ggagatctga
     4621 agtgaacaaa aacaaagctt ttgagcgtac atcggggtaa aagatactgg gtaaattaag
     4681 ttcttgctac gggtaaatta atcactgctt tgatcggcct gctgtttgag catattgtta
     4741 tatgactgat gctgtgtttt tgtgcaaaac ttcctttgct ttatatcctg taaagtgcta
     4801 aaatagtata tgagaacgtg tagcagttac tgcgtaagtc cggttgcttg cttcacgttt
     4861 tattttttgc gaggtgatac ttatgtataa aacgggcgat gttgttatgt acggtacaag
     4921 cgggatatgt agggtcgcgg ctgtagaaaa acgtgatctt accggagaag aacaggaata
     4981 ctatatactc agaaatatat attccgataa aaatatctat tatgtgccgg taaataacga
     5041 agctgcactt ggcaggatgc acccggtatg tacaaagtct gaggtcgatg aactgatatc
     5101 ccatatgaat tccgaaggat tgatatggat agataatgac aacaagcgca aggaggaata
     5161 cagccgtatc ataaaggatg cggacaagca cgagatcata agactgatca agacccttta
     5221 tcttcgccgc agagaacttt cagaaaacgg caggagactg cgttcttccg atgagaacta
     5281 ccttggtata gcagaagata tgctttttga ggagtttgca tacgctctcg gtatagacag
     5341 gtgcgaggta gtggattata tcgaaaagca tctggcatag gccgtatacg gctgtaaaaa
     5401 ctgatgtgcc gtagatatgc gatggcagaa agacgtattt ttacgtaagc ggacaaatgg
     5461 ggtgtattac gattgacctt tttgacacgg tgtgatataa tttatgtgta taccacttgc
     5521 tgaggaaatg catggaactg cggacgcagg aatacttcct tgaagtggtg cgtgaataat
     5581 aaatatcaag tcgtaaagga gaactataat gaaagtgctg atacttaacg gaagtcctcg
     5641 tgtgaacggc aacacttcca tcgctgtaaa cgagcttgta aagacctttg agaaggaagg
     5701 catagcaact gaggtctgtc atatcggaaa taaggatata agaggctgta tcgcctgcgg
     5761 aaaatgttct gcgcagggac gctgtgtgtt cgatgatgca gtgaatgaga tcgcggcaaa
     5821 gtttgaacag gctgatggtc ttgtagtggc ttcgcctgtg tactatgcat cggcaaatgc
     5881 cacacttatc gcctgtcttg acagactgtt ctacagctcg cattttgata agactatgaa
     5941 ggtaggtgcg agcgtagttg tggcaagacg cggcggctgt tcctcaacgt tcgatgaact
     6001 caataagtat ttcactatct cgggaatgcc tgttgcatca agtacctact ggaacagtgt
     6061 tcacggcaga gaagcaggag aagcggagtt tgatgctgag ggtatgctga caatgagaag
     6121 tctggcaagg aatatgtcgt tcctgatgaa gtctatcgcc ctcggaaaag aaaaatacgg
     6181 actgcctgac ggtgaaccat ggcagcctac tcattttata agagatgatc tgaaataaag
     6241 gagtgatatg taatggcaga aaagatcgta cagacggcag gcagagatca gctgggagaa
     6301 tttgctccgg attttgctcg tttcaatgat gatatcctgt ttggcgagaa ctggaacaac
     6361 actgatatcg acctgaagac aagaagtatc ataactgttg tggcgctgat gtctcagggc
     6421 gttacggata attccatacg gtatcatatc atgaatgcca aaaaccacgg tgtatcacag
     6481 gcggaaatgg cagcggtcat cactcacacc gcattctatg cgggttggcc tcatgcgtgg
     6541 gcggtgtttg gcatagcaaa ggaagtctat gcagataatg cacctgctct ttccgaaaag
     6601 gacagatttc aaaaagaact gttctttccg atcggtgagc cgaatccata cggtgatttc
     6661 tttgtgggac aaagctatct tgcacctgtt tctactgagc agataccgat atacaacgtg
     6721 acttttgaac ccggctgccg caacaactgg catattcatc atgcgaagaa cggaggcggt
     6781 cagatgctta tatgtgtcgg aggtcacggc tggtatcagg agtatggcag ggaagcgcga
     6841 ccgcttgctc ctggagatat agtcaatatc cctgctaatg tcaagcactg gcatggcgcg
     6901 gctaaagaca gctggttcgc acatcttgct atagagatac aaggtgaaga cagcagcaca
     6961 gaatggtgtg aagctgttaa tgatgaagat tatttaaagc tgagatagca tttgtgatcc
     7021 ttagtgctga tatggaacaa agccccctgc aaacgctgtg tttgcagggg gcagtttgtg
     7081 tttatcggta tttggaaagc ggatgacagt tattatctgt tccgctggtg ggatgcctgt
     7141 tattgattcg ggatatatgc atcaagcagc tgctgcagca tcctgtcacg gtcgaaaagc
     7201 agtctgtcaa gctgatccag ctgcttttcc agcagtgaga tagaacgctc ataagcattt
     7261 tttctttcct catatatgga taaacgcttt tcaaattcgt cgtgcttgct ctcgagctgt
     7321 atcagaagat catctacctg acggttgcgt tctttcagca tctgtttgag ggcagccaca
     7381 tcgtctgtgg tgtaatcatc gccgtaaacc tctataagcg attcgtaaat gggagctatg
     7441 gactgataat gaaaattctt ttcctccgag ccctcggcaa atatatcgta catcgtcctt
     7501 ggagatacat atccgccgtg ttcggcaacg atatcctgta tctgcgggat agacatacca
     7561 tgctgattct tgatctcctt gatagtcttg attcgttgtc ttaaagttct ttccataaaa
     7621 tatcctttca aaaacttgca agaaacttgc aggattaatt cattgtcaaa tccctactat
     7681 tcatgtataa ttaatcacga tgctttgcta tttgaacgaa gggtcattca caatatccga
     7741 tttacagctg ttttacaaaa acgagcacag ttaacatttt aacataagtc ggtaaatttg
     7801 tcaaccgctg caaagccttg cataagtctg tggataaact tgcggaattt tctgatctat
     7861 cattgcaaag gacagcagca aaacacatca aactgatcgg taaaggagag gtcataatga
     7921 atatggtcat gatagaagaa aaggaagaac tactttcggt aaaactggct gaaagattga
     7981 agaaagacgg gtttttcgtt gttgcacatg gtactgtact ggaaataatg aactacattt
     8041 ttgaggtaaa gggtacaggc ggtcagccga ggcacaacgg actcagatat gagcttcctg
     8101 cagagtacgg tgaagatacg ctgtacagct atatcaagat gaccgtttcc acaccgctcg
     8161 aaaggaaagt ggaggatatg acagtagata cggtattatc actgggtata tcaagggcgc
     8221 tgaggggata ctcatatctt gcagcttcga taactatgtg tgtagcctgc cccgataagc
     8281 tgtattctct gaacaaggat gtttaccccg agatagcgag aaaatacaat gttgatgtat
     8341 cctgcatcga acgaagcatc cgccatgcta tatgcaaggc ttattcggag gatcccgagc
     8401 ctatgaaaaa actgttcagg cggcctatca gacgtccgaa atgccaggaa ctgatcgccg
     8461 agtgtgccga tatcataagg cggatattct attgacggat caccggaatg gtctgatgca
     8521 aaagccttcc gaggagacgg aaaagcttat ggaaaaatat aaaccgaaat gaccgcccta
     8581 gtccgaggac ggtcatttta tacccgtaag aagaacctgc agcacgccac ggaaatcaat
     8641 tttcaaaaaa tcaggtttca aaagttacat ttatatttca ggttgtacaa attactggac
     8701 agagcacctg gaaaatgata taatataggc atgaataatg gaataaccga gtattttgaa
     8761 gatattgaat tatatgagga atatgacggc tatttttgca gtatccccga tatcattaca
     8821 atagcaattc ttggaagtat ctgtggactt agaaacattc atcagattca tcaatgggcg
     8881 acaaatgaca gagtaagcga attcttaaag gagaaattcg gaatcgatca tgtcccttgc
     8941 tattattgga tattgagcct gctgaaatat gtcaagcccg aatcgctcaa ccgctgtttt
     9001 gcggattggg tctattcatt catgcccgaa aagtccaaaa gtatgacgat ctctcttgac
     9061 gggaaaactg tttgttcgac acttaaaatg agtaagatcg aaagtcctct gcacatcatc
     9121 agcgcacagg tatgcgaact tggattgacc ctggcacaac gcagcacgga cgataaaagc
     9181 aacgagatac ctgcggtgca ggagcttctg aaagaaccga aaataaaggg taatatagtt
     9241 gttgcggatg cactgaactg tcagaaagaa actgctgaga ttatcgtaaa acaaaaggca
     9301 gattatctgc tttgcgttaa ggataatcac ccaaatttga agaaagatat cgaggattat
     9361 gtgcaggaca gttctctcag agacactatg caaacagttt caagaacgga gaaaaaccgt
     9421 ggcagagttg aaacaaggac agcgtatgta acaacagata tcaactggct ggaacagaaa
     9481 aaagagtgga aaaatctgaa gtgcatagga gccattcata ctgagttttc aacgaaaaaa
     9541 ggcacttcga gcgaatggca ctattacctt tcaagccgcg aaatgacagc ggaacagctc
     9601 cttcatcatg caagaatgga atggtcggtt gagtcaatgc actggctgct tgatgttcat
     9661 tttgaagaag attggtgcag agtcgaaaac aaagacgttc agcaatgcct gaatatgttc
     9721 agaaaagctg cgataaattt aatcaagaac tttaaaaatc ggaacaattc taaagccgcc
     9781 atatccaaac ttatgtttga atgtcttatg gagccgcaga tgatttcgag ggtgattttt
     9841 gaaaattgat ttccgtggca gcacgctgcg cagggttgac ttaattatgg aaatatgtta
     9901 taattatata aatttttctt tcgggatcat cacgtatccc gaagagatgc ttttcccgta
     9961 caaaggcgcg ggatacagct tgtgaaggag gtagtctttt atgaaaatga cagtaagtca
    10021 ggcaatggta gagtgcttga aggcagagga gataaaggtc gtctacggct acccgggtgc
    10081 ggctatctgc cctttttatg atgcactgct tgatgctgaa aaggatataa agcacgttct
    10141 ggtaaggcat gaggctaacg gcggtcatgc agccagcggc tatgccagga tatcgggtaa
    10201 gcctgcggtg tgtatcgcaa cttcaggtcc cggtgcggtc aatctgataa ctgccatagc
    10261 tactgcctat gcggattcta taccgatagt ctgtatcaca ggtcaggtaa ataccgatca
    10321 gataggctcc gatgtttttc aggaggctga tgttacgggc gcggcagaac ctttcgtaaa
    10381 gcacagctat ctccttaaag accctgcgga tgtgggcaga gtgttcaagg aagctttcta
    10441 tatcgcaggc tcgggcagac cgggtcctgt tctgatagat gttcctatgg atgtacagaa
    10501 aatgactgtg gatttcaaat atcccaaaaa gtgcgatata cgcagctata agcccaccgg
    10561 caagggaaat gcattacagg taaagcgtgt taccgaagcg ctgagaactg ctgaaaagcc
    10621 acttatatgt atcggcggcg gtgtgttcgc ttcaaatgct caggctgaga tagttgagct
    10681 ttcagaaaag ctgaacatac ctgttatcac taccatgatg ggtatatccg tgttctctga
    10741 cgatgatccc ctttatgtgg gcatgatagg tacacatggt acaaagatag caaattatgc
    10801 tgtaaatgct tgtgacacac tgttccttgt aggcgctcgt gtcggtgaca gagcagtaaa
    10861 aactcctctt gagctggaaa aagataccaa gatactacat atagatatcg accctgccga
    10921 gataggcaag aatatcggtg cagacctgcc gctggtaggt gatgcaaaaa tggtgctccg
    10981 tcagatgctt gagcatatag ataagcaccc tgagggtaat gccgatcata cagcatggct
    11041 gaagcagata gaggataacc gtaccccaac cgagtttgcc aagcccgtca agggtactgt
    11101 caatccgaag gagtttctgc agaagctttc cgagcgtatg cctgcggatg taaatatatg
    11161 cgcagatgtg ggacagaacc agatatggac aagcagatac catttcaaaa aaggcggacg
    11221 tttcctgaca tcgggcggta tgggtactat ggggtattct ctgccctgtg ccataggcgc
    11281 taaaatggca gatgaaagcc gtgtgaccgt ggctgtctgc ggtgacggcg gcttccagat
    11341 gaatatgatg gaacttgcta cggcagtgca gtatggtgtt gatgtcaaag tggtagtatt
    11401 taccaatacc agactcggca tggtaagaga acttcagacc aagggctata acgacagaca
    11461 gatagcagta ttccttgacg gttcacctga ttttgtcaag cttgcagccg cttacgggat
    11521 acctgccata agggtaactg ataagaagtc cgaggacaag gctatcgaga tgcttgcaga
    11581 agaaaaaggt atgctgctgt gcgaggtagt tgttgacaag gatttcccga cgctgtaaga
    11641 ggtgggtcat gctgcattac aggatactga gttacggcag tgactacgat tggggattac
    11701 tggtgggtct gatatctctt cgcgatgcgg cagagataga caggcagttt gaaaaaaggc
    11761 tgaatagtct tgaaaaggaa gaaccctttg ctgacgatat gtccgccagg cttatggcag
    11821 agctggataa ctcacgcaga acaggcgagt atgctgtcat aacgccaaag ggcaagggct
    11881 gtataacctg tctttcaacg tccataaaat tcggactgat ggtgctggac tcacataagg
    11941 acggtcagcc tgtaataaca aggacgggtg ctgtaaatgg cagagtactg gaatggctct
    12001 cggaaaaagg cgattttacc cttgtgctga cggataacga gtgcggtgct ttgcgtgaag
    12061 tactggcgct tgtgggcaac ggtatggctg acctggaata tcaggggcag atctattcgg
    12121 cttatgatat aaaggcgtgt atggaggcag tcgcgcagct ttcagacagc tgatatcgga
    12181 tagtatttgt gtaatattta tatatcagcg ctttatcacg ccataacaag gataatttac
    12241 tgtgataaat gactaaattt atccgttaat aatttagtct gataaattta aagaaatagc
    12301 cacaatatga tagtataata attaagtgtg gaatttattc ccgcaaaaaa acggaggtca
    12361 tgatatgaaa cataccattt ctgttctcgt tgaaaatcac agcggtgtcc tttcaaggat
    12421 atcgggtctt ttttcaagaa gaggattcaa tatcgaaagt ctggcggtag gtcctacaaa
    12481 tgatgaatcc atatccagga tcaccatagt tgcagacggc gacgagcata ccgtcgagca
    12541 gatagaaaaa cagctcaaca agctgatcga ggtcataaag gtcaagacct tcggcagaga
    12601 tgaatttgta gcgcgtgagc ttatgatagt aaaagtcagt gctcctgctg acaagcgcag
    12661 cgagataatg actatcgcag agatcacagg cgctaaggta atggatatca cccttaccac
    12721 catgacgctg gagatatgcg acaggtatga caggctggaa agattcgaga aggtaatcga
    12781 gccttacggc atactcgaaa tggcaaggac aggaactgtc gctgttgaga gaggcgccga
    12841 gtatttcagc gcaaagaagt aaagaagtag attccccttt ttacagggag aaataaatca
    12901 ttccaaatat tttaggagga aattaaaatg gcagatgcaa agatctatta tcagcaggac
    12961 tgcgacctta atgtactgaa gggcaagaca gtcgctatta tcggttacgg ttcacagggt
    13021 cacgctcacg ctctgaacct gaaggagagc ggtattgacg ttgttgttgg tctgtatgca
    13081 ggctccaagt ccgcagaaaa ggctaagaag cagggtctgg acgttctcag cgtagctgac
    13141 gcagtcaaga aggctgacgt tataatgata ctcatccccg atgagaagca ggcagctctg
    13201 tacaagagcg agatcgctcc taacctgaca gcaggcaaga cactgatgtt cgctcacggt
    13261 ttcaatatcc acttcggctg catcgttccc cccgctgatg ttaacatcgt aatgatcgct
    13321 cctaagggac ccggtcacac tgttagaagc gagtaccagg ctggcaaggg tgttccttgt
    13381 cttatcgctg ttgagcagga tgctacaggc aacgctacag agatcggtct ggcttacgct
    13441 ctgggtatcg gcggcgcaag agcaggcgtt ctggagacaa cattcagaac cgaaactgag
    13501 accgacctgt tcggtgagca ggcagttctc tgcggcggcg tatgtgctct gatgcagtgc
    13561 ggtttcgaga ctctggttga ggctggctat gatcccagaa acgcttactt cgagtgcatc
    13621 cacgagatga agctgatcgt tgacctgatc tatcagtccg gtttcgaggg catgagatac
    13681 tccatctcaa acactgctga gtacggcgat tacatcactg gtcctaagat catcactgag
    13741 gataccaaga aggctatgaa gaaggttctt tctgacattc aggacggttc cttcgctaag
    13801 gagttcctgc ttgacatgag cgatgccggt tctcaggtac acttcaaggc tatgagaaag
    13861 ctccacgctg agcatccttc cgagaaggtt ggtacagaga tcagaaagct gtacagctgg
    13921 aacaacgaag aggacaagct ggttaacaac taatcttttg tttctgatta ttacaaaatg
    13981 ctcttccgca tttgcgggag agcatttttt tgatatatat tattacaaat actttgacag
    14041 tttgtgtatt cttaataaag caattaggtt attatccaca aaaaaacact tgacttttaa
    14101 tatcgatata ttatataata tataaggtat agcatgcaaa agggaggtgc agagtttgaa
    14161 cgatactttg tatccaataa tgtacatcga agtaaacctt atatctatat tgttggtcct
    14221 tgtgatagga cgtaagactg ctggactttc aaaaatggtc tcacatcgtg attttgtaaa
    14281 tgctatctgt gcgatgatct ccttttttgt ttcggataca gtgtgtgtta ctatgaccgg
    14341 aggtctcctg ccttttgtgc ctatagtgct gcttttattt aaggcgatct attttatttc
    14401 cacttctgcc atgtgctttt tctggtttat ttattatgaa catatacaag actcgtcatt
    14461 tgccaaaagc aaacgcagtg tttttgctgc atcctgcctt gtttgggcta tggctgtagt
    14521 ggtcattata aatatatcca atggggtgct gttctatatt gatgagaaca ataagtattg
    14581 cagaggaagt atgttcaatc tgctgtacct gctttcgtat ccgtatgtga tgataacttt
    14641 tatacgttca attttagcta tattccgcag ggaaaactat gcgaaacgaa atatgctaag
    14701 aaagctggcg ctgtttccgc tggcacccgc agcttcgggc atagttcagt atttcagacc
    14761 tgaaattcct gtagcctgtg cgacattgtc actggctaca ctggaattat atcttgaatg
    14821 gacggacagg atgatatctg tcgatccttt gacgatgctc ggcaaccgca agcagatgga
    14881 gtacttttac aaacaatggc aggaggactc cgattccgat acgatgtttg taatgatggc
    14941 agatgcaaat aagttcaaaa gcatcaatga tatatacggt catgttgaag gcgatgctgc
    15001 gctggtgcgt atcgcaaatg ctatgcgtac ttcctgccgt gagatgaaca ggagagctaa
    15061 tatcgccaga ttcggcggag atgagtttgt tataatggta tgtaccgatg acgaaacggt
    15121 gatctcaaag ctcaggatga ggttggatga atgtcttgaa caaatgaaca cagccgataa
    15181 ttcaccgtat gaactgagga tctgcgtggg agttgctatc gcaaagcgaa gctcggatct
    15241 tgaggagata atacagcagg cagatgccaa gctctatgaa gaaaaagcaa gacttggcca
    15301 tgtcagataa taggatagta tgatctttag ctgagatcac tttataatgc gtgataattt
    15361 tggggaatgc ttatgagata ctatatatat ggttatacag ataaaggcag cgtaaaggga
    15421 aaaaatgagg acgctgtgct ggtcaataaa gaagtcgtaa aggaaggctt ccgtgaagca
    15481 gtgcttgatg caccgtttat cacggcggtc tgtgacggcg ttggcggaga aaacgcaggc
    15541 gacgttgctt cggagctgtg cctgcagcag ctttcagagg tggtgtatac atcaaatacc
    15601 gatcttaaac aggtgcttat ggcgatccac ggaaagatca aaaaacgcag cacccttgac
    15661 aaggcatcgg ctaatatgca gacgaccctt tgtgcactgg ctgttgacga ggaaggcaaa
    15721 gggctttgtg tgaatgttgg tgacagcaga ctttacaggt acgtcaacgg tactataaga
    15781 cagctgacca cagatcagag ctatgtgcag tatatgtaca ataaaggcga gatcgattat
    15841 gtggatgaga tagagcctga gtacaggagc gcgattattt ctgctatggg aagccctcag
    15901 agtgatccgc agatcgagca gacaccactt gcgaatgaat tcggagcaga gcctgatgac
    15961 atgataatta taacctctga tggtttgtcg gatcatgtca gtgagaatga gtttgaggta
    16021 ggtctttcta tggatctgcc catatctgag aaactcgttg cgcttgcaaa gcttgcgatt
    16081 ctcaatggca gtaccgataa tgtatcaatt ataggtatca agccattctt tgattttgaa
    16141 gaactggcag cactgacaag gcatgatgct gttggcaaaa ctgttaatgt catggagatg
    16201 ctggaagatc acaatgaaac tgaggaaaag gacgagctga gcgatatcct taccatagat
    16261 cttgacgcta taatcggaaa aggaaaaacg cagcgcgaac ccgaaaaatc ttatgagata
    16321 gcatccgcca aagttcccga gccagaggaa tccgaagaaa caccgatagt tgaagccccc
    16381 gagcccgagg aacccgacga aacaccgata gttgaagccc tcgagcccga gaaacccgac
    16441 gaaacaccta tagatgaagc ctccgagccc gaggaacctg acgaaacacc gatagttgaa
    16501 gcccccgagc ccgaggaaat cgaagaaaca ccgatagttg aagccaccga gcccgatgaa
    16561 cccgaagaaa caccgatagt tgaagcctcc gagcccgatg aacccgacga aacaccgata
    16621 gttgaagcct ccgagcccga tgaacccgac gaaacaccga tagttgaagc ccccgagacc
    16681 gaggaatccg acgaaacatc gatagttgaa gttcccgagc ccgaggaacc cgaagaaaca
    16741 ccaatagttg aagctcccga gcctgaggaa tccgaagaaa tacacaacat taaagaattc
    16801 gaaccggagg agcatcatga catggtcagc agggaagata tagaacttga agcgcacgat
    16861 ctgtttatgc aggcgcaggc ttctctctcc agattatcgg gtctcatacc aaaggataat
    16921 aagtctgaat aaacaaaaag gtcattaacg cttctgtctg tatcgggcag aagcgtttta
    16981 tattgttggt tctcaataaa attgtctcaa aaactttggt gaagttattt gttacaaagt
    17041 ggtaaaacct gttgaatttg aaacgaaaat gtgttatcat attatacagt acaaattttt
    17101 aacgcaaagt cctttgtata agaacaggag aagtaaaatg gcttacggag attatggaac
    17161 atataacggc ggcggcggat atgcttcgca ggctgaccgt cacttggaag ttgatctcaa
    17221 atgtccgaat tgcatgggcg agagagatat tgatgtgaat aatatgtacc taatgtacag
    17281 cctgtgtatc agccggcgag caatagcagt attcttttgt gggtaatcgg tttcattttt
    17341 gcgccttggc tgactgtacc gttatggttc ttcaagacga ataggatatc ccgaaaaact
    17401 aagataatag tagtttccat attagtactg cttttcatag ccggggcatc ttcatgataa
    17461 ttataatatg acactccctt tatgggggtg ttttttttac aattatcggt tgcataataa
    17521 ttgcggataa gagaattgat ttttgataaa ttttgtcgct actatgaata aagttagaaa
    17581 ttcgacccga ttaacctata aaatttgatt taaatgacga aaaagttttt gatttatgaa
    17641 taaccgttga caaagcgtgg caggaatggt aacatattaa tatatatggc ttttcgtggc
    17701 cgtatgttat ttttttgagc ttgttatcac cgcaataaat gcagatagca aacctgaaga
    17761 atatagctgt accgatcttt cgggaaaggt gcagctgagt aattaaggag ggggaatgta
    17821 aaaaatgaga aaaagtactc atagaccgca gtacaggctg ctttcgggat ttatatcgct
    17881 gatatgcctg tttacggcgg ttctgggcag tgtgccctca gtgagtgcgg catcagccga
    17941 attgcccgaa aatatccagc ttttctttaa caaaggtgag gatgaagtgg atggcgtggt
    18001 catttcaaat gacggaaaga ccgcggatta taccattgag ggcgataagc agcaggtcaa
    18061 tgttacgctt agactcagcc tgaacaagac ctatgaagaa ggacgtttgc agatagaggt
    18121 gccttatgat gcctttaccg atcgacgcgg cgatcctttc catctgtcag caaaggctga
    18181 ttttcttaat cagcttgctt cggattcttc acttttgagg gtcaaggagg acagatcaag
    18241 tactgacggt gtaatagttc ttgagaatat caaggcttct tcaccgcata tcgaccttaa
    18301 tcttcactat accatctatg caaatcaggt tgtcgataac agtgtacagg attacggtat
    18361 aaagatattc gataatgaaa cacaggaatt acgttcgcct gaaaagatca cagcgacatt
    18421 ccgcacccat gtaagggatg cgtctgttct gaagtatacc gaggacgaag gcgttcagca
    18481 gggctgctac tatgcctggg atgatatcat cgaaaccaga tatcatcttt cagagtatgg
    18541 tataggcgag gctgagttca atgagatgct gaaggagtat gacttcatcg gctaccgcct
    18601 taaaacttcc gtagagaaga atcagcccgt tgttacctat attgacgatc agccgggcgg
    18661 cggtgaagtc gtagcagtat caaagaaatt caactatgag gatactactc ctcttgtaaa
    18721 ggtaactgag ggtgagtatg caggtcagtg gatgtttgaa ggcgcagcat cggagtatct
    18781 ggtgctggta aagtatccca agacagttgc tgaaaagcct gatgctgagg gcaaactgcc
    18841 cagactgaga aatgatgtca ctgtgaccta tgcaggtgtt gacggtgaca gagaggatat
    18901 taccgaagac agcgactata tcacatcagt atggcagaca atgggcgctg tttacagcgg
    18961 tgatatatgg agcgttgtaa agaaagcagg tcccgatccc acaggtgctg tggatcttct
    19021 gagggcaggc agcgaagctg cgctctccta tgagatcgag ggtatcggtc atacatataa
    19081 gtacggtgcc aaggataact tcacctatga ggacggtccc tactggatgg aagtggttga
    19141 tgatgcactt tatgtaaacg gtcttggcga ggacggcaga gaacttgctc gtctgcagcc
    19201 tgatgatttc tacttcaaga ctttcaccat gaccgttgag cataaggtag tagaagcggt
    19261 aacactcaat cttgatgtaa agaaatccca ctatcttcct ataaataaga gaaagcctgt
    19321 tgaggtatat gtcatgactg ccgataagcc gggtgtatgg caggaagact gggtgttatc
    19381 tctccctgca ggcaatagcg attatgtcta tgctgatgca gatggcaata ccacattcga
    19441 gttcaagcac gacaaggtat acaggatcaa gtttgtatac cgcgatgcta acggtgatat
    19501 cagcctgaga tcgaatgtta caggtgttat ccgcggcaag ggacctgttg tcaagcaggt
    19561 gcttgataat atggaaaata accacatcag cgatttccag gtgttcaact gggatggtca
    19621 gatgggttat aatgctgcag gtgtatggga gaaccccacc gacggcagaa caatatatac
    19681 tcccaatgac agtgtcaaga aagatctgct ggctcttgat gaggagctct atgcaggaca
    19741 ttccgatgaa gagggaaatg taaaggtaac taccagactt tccgctaaaa atgtgctcac
    19801 aagcattgat cccttctgtg gactttccaa gaagtcaaac ggtgttgagc agaagaacaa
    19861 gaaggtatat acttcttatt atctcgcagc tgtaacaggc aaagccctga cagagaaaga
    19921 tctcagacag ctggtagagc taggcgctat aaagggcgat aaggaggtcg tattccacga
    19981 gctgctgcct atgggtatga gtgttgaaga agttaccccc atgacagaga ccctttatct
    20041 ttccgacaga cccaaggagt atcactggga tacactgtgg gcgcgtaaca gcggtcatgt
    20101 aaaaccgata aataccgagg tgcccgatgt aagtatcgaa actatcgaca actacaaggg
    20161 aactcacaga cagtatgcaa agatcactgt aaagtacaag gatcttcctg tggtaagact
    20221 tggcgaacag agcgatatct gctactctct cggttctgtg ctgtatctga aggcagtagc
    20281 tgactatgag gagctgagaa gcactactct tgataactat gccgaggcac agttcatagg
    20341 caaagacggc aagcctgtag agcttgcagg tatcatggca aagtcggatg acggcactgt
    20401 ttttgaaaca ctgaaggaca gggacggcaa gcaggcgctt gaagatatcg acggcgataa
    20461 tgatacaaag aaaactacag ttgtagctga tatggcggtg gatgaagtaa ctatgtatta
    20521 ctctgccacc acccttaaaa agaagatcaa ggcagatgac tacgatcttg acttcaagga
    20581 tttcacccag acctatgcag gtcataacta cacctacaga ctccagttct tctccaacga
    20641 gggttttgca aagaatgtgg tgatatatga ttccattgag gaagcttaca aggaacccga
    20701 atttgatggt atgccttact ggaagggtac gctctacgga gtggatatca gcgaggctga
    20761 ggaagagttc ggtgaagtta aggtattcgt aaatacagat aaattctatg aagagatcga
    20821 gatggcaacg gataccttgc ttggcaagcc gggtcttaca cctgatatgc tcaccgagga
    20881 taataactgg tatgagatag atcccgataa ttatgataac tgggaaaatg tcaagaccat
    20941 agcattcaag atcggtgaag atgtaaagtt tggttcaggt gaggatatgc ctcatacggt
    21001 atgcgtatac ctgaagatga aagcacccga cactatccat aaggatcaga caaagaccaa
    21061 acaggtactg gcttacaatg cacccgctta ctactgcgaa aagtacatac agaccaagtg
    21121 ggtcaaggat actactatag caaatgtagt tactataggt cttaaatccg cagttgagaa
    21181 attccctgcg ataagcaaga catttgaggg cgatatgcct gagggattca ctgagaactg
    21241 cgagttcgat atcaagcctc ttaatggtgc acctgcaccc aaggcctaca aggacggcaa
    21301 atggggaagt gccataaaga ctgtaaaggt tgccgtaaac ggttcagaaa cagcaatagc
    21361 cgatgacaac ggcagtctgt tctttaccga accctgtgtt cttgaatacg aagtatccga
    21421 gaaggcaggc acaaggaacg gagttaccta ttctggcgag aagtataagg tagtgttcaa
    21481 tgttaccgat atccgcaagg acgttcagta cgatgacaat accgaactta ctgtagatac
    21541 aaagatctac cgcactcatg atgagaacgg tgatgaactt gacagacctg cagcggtaca
    21601 ggctgtaaca tttacgaata agtatgcacc catacccgta aaggtcaaga ttcctgttat
    21661 atccaagagg ataaagggca gcgaaagacc tgaggaaaag cagttcatat tctcggtaca
    21721 gccctttaca actctcggcg gcagagcaga tgttcctgcg cccgaaaaga caagagcagt
    21781 tatcaagggt gagggcactg ccgatttcgg tcaggtcgaa ttcaccgagg caggacagta
    21841 cgattatgca atatatgaag taaactcagc atatacggga tatacctttg atacaagagg
    21901 gtatctggta agatttaccg ttaccgatga tgacggcaag ctgaaggctg ctgcagctcc
    21961 tctgcaggtg ctgtatcccg aaacaaggga gtatgagccg gctgaaaagg cagagtttgt
    22021 taacacctac acatctaaac ctactgatac agtggcattc cctgatgtag taaagatgtt
    22081 cagcggtaag gaaagacctg atgataaggt attcagcttt acgatctctg caaaggacgg
    22141 caaggacata cctatgcccg agaacgatac cgttaccatt gagggcacag gcaaggcttc
    22201 attcggcggg gtcaaatacg atgcagcagg agtatatgta tatgagataa aggaaaatga
    22261 tctcgatgac agctactcag gctacaccaa ggacaaaaca gtatatacat tcacagttac
    22321 cgttaccgat aacgacagca tcctttcggc tgaaaccaag cttacaaagg acggtgctga
    22381 gacagcatct gcagagttcg ttaacgacta cagtcctata gttgcagctg tagttcctcc
    22441 tgttgctgtc aaggagatca agggcaacga tcccgatgct gacgagcgca tctttacctt
    22501 tgaactggca gcagctgagg gagagtcagt acctatgcct gaaaagacaa ctgcgacagt
    22561 aaagggcagc ggtgaggctg atgctttcgg aaccatcgtc tataatgagc ccggtacata
    22621 ccgttatgtt gtttatgaaa aggatcttga tgacagctat gcaggctata ccaaggatga
    22681 tgctgtatac accatgatcg ttaacgtcag ggatgcaggc ggaagatata aggctgtgta
    22741 tactctggaa aagaacggcg aaaaggttga tgaactcagg ttcgtcaata cttatcagcc
    22801 agctcccgca gaggttgatc ttgagatcga aaagcagatc gagggcacaa ctcccgatga
    22861 ggacgagacc tttacctttg agctgacagc taagggcggc gctccgctgc ctgaaaatac
    22921 aactgccaat gttgcaggca caggcaaggt ttcttttgac agctggtcat ataccgaggc
    22981 aggcatttat gtatatgagg tacgtgagat cgaaggcaga aatccaaagt acacctacga
    23041 tgaagctgta tatatagtaa cagatactgt atccgatgaa ggcggtgtgc tgactgtgag
    23101 caggactatc accgactttg acggtatacc ttccgacaat gtggtattca taaatcgcta
    23161 tgatgatgac tgggatatca caagggaaga ggacagcagt gcgacaccag caggcggaga
    23221 agagtcctcc gaaagttcag aggattcaag tgaaaattcc tccgaggaag agtcttcaag
    23281 cagacccgag gacagcagca aggacagctc ctcaaagtca gacagttctt cttccactcc
    23341 aaatacatca aaccccaata caggtgcaaa gagccttgtg ggcgttgaga tagtgatgct
    23401 tggagcactg gtatgcgtta tgaagaaacg caggaacagc aagtaaaaac agctgagaaa
    23461 aaaataagac acttctgctt caaaagcagg agtgtctttt tgtatgtcgg gtataagtta
    23521 taacaagtac catatgaaca taaaaaaaca ccgttcagat gaatccgaac ggtgatggat
    23581 tgcgggagta ggatttgaac ctacgacctc cgggttatga gcccgacgag ctaccaagct
    23641 gctctatccc gcgatatttt tttgttctct cgttgagtac ttgtctatta tatcataaat
    23701 gaaagtgatt gtcaataggg tttcaaaaga aaaatcaaag tttactttat gttaacattt
    23761 atatgaaatg actttctgtt gttctctgct ttgacgatct tccgtatgcc ctgatatgta
    23821 ataaatgcaa cgatattata caatattaac atttaaacca gcggagcagt cagaacggat
    23881 gagaaagaaa ttgtttcgtt aaataaacaa aatatatgga tgatcggctt ataaagtctg
    23941 ttgccaattg tgc
//
