LOCUS       c00042_NZ_ADJN..       16595 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_ADJN01000027.1 Peptostreptococcus anaerobius 653-L contig00078,
            whole genome shotgun sequence.
ACCESSION   NZ_ADJN01000027
VERSION     NZ_ADJN01000027
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:18:13
            Original ID  :: NZ_ADJN01000027.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4795
            Orig. end    :: 21390
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16595
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14795:20284]"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15489
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /neighbourhood="10000"
                     /product="proline2aminovalerate"
                     /protocluster_number="1"
     cand_cluster    1..16595
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Proline_reductase and (Pro_racemase or
                     GRDB) and not ACP_syn_III_C)"
                     /kind="single"
                     /product="proline2aminovalerate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16595
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="proline2aminovalerate"
                     /region_number="1"
                     /rules="(Proline_reductase and (Pro_racemase or GRDB) and
                     not ACP_syn_III_C)"
                     /tool="gutsmash"
     CDS             1976..2953
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MSIKKNKFTFICALILILMPITFLACKQDEIVASTDKFDVRLSEV
                     NDNIKLAKFEYNSIFGDDSWKSVVVSSDGSTEQFKKSVIDYLIMSHYKDEENKKNGYSY
                     SEEELNDMLDSAKQNIEEDKIKSNEYKSLNIDDHVLKKYIRDKMIENKNQEEFNKRVKI
                     KEEDIKKYYKDKINEFKEKEFDCYQIWIKNPNDKIKAENAYKDLKKGMDFSTVVKKYSE
                     DENSKNKGGYIGKIKKENLIPELREKALIMRDKEYTGVVKSKDGYFIIKIDNQRNLTKT
                     LDSCRTKIKDDLLEKLYQENNKKIINRIGVKYYKDNIKKIKIQL"
     CDS             3163..4260
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="VNSMNRKVQKFIVALGLVGTLGSCSFADVVVDVSDASSKGKVAID
                     NNPVINEQASDGSIKVVDTKKLSVERIAGKNRYETSYKISEALGEYKNIVIASGEDFPD
                     ALSAGLLASHLKAPILLTEKKSADKYLLDTLNRHKNQQYYIVGGENSVSKNTKESIQAF
                     SKDSIKILAGKNRYETSSKVASMIDKDIFGNDYATDMLAVYNGEDFPDALAATPFLYQN
                     NNDKKTRTPITLAWNPKVKVDSDILQIVFGGESFLPRGNEKLRLAGSNRYKTSVEVAKA
                     FKTVLNKDIDTVIIASGEDYPDALSAGPLASSKNAAILLTEAKGLNPDVKKYIEETKSI
                     KNVIIVGGESTVSAQVEKDLATIAR"
     CDS             4491..5588
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="VNSMNRKVQKFIVALALVGSLGSYSFADVVVDVSDASSKGKVAID
                     NNPVINEQASDGSIKVVDTKKLSVERIAGKNRYETSYKISEALGEYKNIVIANGEDFPD
                     ALSSGILASYLKSPVILTEKNSVNPYLYSALNTHKNQKYYVIGGKSSISEKVMEDIKHF
                     SPDLTSRISGKDRYETAGLVTSKIIREIYNSYGYPDNLAVYDGSDFADAMSATPFMYQY
                     ERNKEKEKPVTVPLPKGYKIDHDKLEVVFGGESFLPKGNEKLRLAGSNRYKTSVEVAKA
                     FKTVLNKDIDTVIIASGEDYPDALSAGPLASSKNAAILLTEAKGLNPDVKKYIEETKSI
                     KNVIIVGGESTVSAQVEKDLATIAR"
     CDS             complement(5686..6999)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RnfC_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_7"
                     /sec_met_domain="SLBB (E-value: 1.3e-05, bitscore: 15.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.3e-39, bitscore:
                     124.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.9e-16, bitscore: 50.1,
                     seeds: 53, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKMIHLLLKQNIGAKNTPVVKVGDEVKRGQLVGTFEGLGAYLHA
                     SVDGKVVDITEDEIIIEANDVQGEDYVKIEKGATIAETVKNAGIVGLGGAGFPAHVKLG
                     TDLGGTGYVLCNAAECEPILSHNMNQLLLEPEKLLRGMKLCMEATNAAHGVFALKEIHP
                     KEIKALEAIIDDERIRIEAMPNMYPMGEERAVVRECLGIELDTDQLPSAANAVVINSET
                     MCAIADAVDDLKPLIEKNITVAGYLNTANSLEIFMNVPIGTRVGDLIDRAGGIFKYGEY
                     GEIIMGGPFTGTSTTVDDYTKKATGGILVTKPYPKGAPKMGLLVCACGGNEARLREIAG
                     YMGSQVVGVEKCKQAIEGKGGALKCERPGHCPGQAAKMLNLKKAGAQEVLISNCTDCTN
                     TVMGVAPKMGIPVHHQTDTILETMGIEKIRFLKDGQKR"
     CDS             7384..9147
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="LFKVPSKENLEDVMQKDFVTADENLKVEDVFEDLITNKKTVITVD
                     RNKNMITGYIGILDIANLVQKKGTSYRQAVLKDIVKKEFIMIDRSYNFRTYTKFLEDEN
                     YMYIVVEDDSVVGYLNAYYVKQNNYPFLNEEFTTLKHIINQVNEGISAIDRDGVVILWN
                     KFMQKRYNITSDEIVGRKMSDYLVDTISERVLTTRQAMSDVYYTKKNMAGTDLYGVVHA
                     FPVFHKEEFVGVVCTEVDVTDASKLSKELELTQEKIKYLEEVKSLSIGEFDKILGKSYP
                     LEKAKNMAKQVAKTNSSIMINGESGTGKEVFARAIHKYSEREGTFIPVNCSAIPQELFE
                     SEFFGYEPGAFTGATKNGKPGIFELANKGTLFLDEIGDMPYNMQAKLLRVLQEREIMRV
                     GGNEIIKIDVRVISASNKDLAAMVKEETFREDLYYRLNVVEINLPSLRERGGDVAILIY
                     EFLEEQCKINNKPFLKISKEALDMLQRYEWKGNIRELKNTMENMVVLSNRDTLEVEDIP
                     VYIRHKVESKEDKETMYPMDLNMAVQILEKNKIQEALEKTSGNRSKAAKILNIPRTTLY
                     YKMDQYGIRDK"
     CDS             10001..11908
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_9"
                     /sec_met_domain="Proline_reductase (E-value: 1.3e-204,
                     bitscore: 668.8, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITNETAKAHANDPAVCCCRFEAGTVVEAANLEDPAIFPDLIDS
                     GLLEIPENALTIGQVLGAKLTQTLDALTPMTTENTEGYALESEEEEEVVEEVAEAPVAA
                     VAPVAQADGVLRIQIAEGKGINLEIPMGAIGGSGVAPSAGVVVPVAEAGAVADEVEETK
                     VLRSLTKKHYKIDKVVFGEKTEIKGTTLTIRNPEEICAEAAATEELVLDLKLDIITPDR
                     YNEYSEAILDLQPIATKEEGELGEGVTRVLDGAVMVLTGTDANGVQIGEFGSSEGAMDT
                     TMMWGRPGAAEFGEIFIKGEVTIKAGTNMERPGPLAAHKAFDYVTQEIREAIKAIEDES
                     LVVDTEVINQYRRAGRKKVVIVKEIMGQGAMHDNLILPVEPVGTLGARPNVDLGNVPVV
                     LSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVMRVMEDEELDLVGVVFVGSPQANSE
                     KFYVSRRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMRGIPVVGVSYCAVQGA
                     LVVGNKYMTHMVDNNKSRQGIENEILENNCLAPEEAHRIVAMLKNAIEGEEVKPAERKW
                     NNNVKLNNIDAIEKALGIEIPLEKNETSLNMTRKRSQLYERADIEAGIVEDTYTPVEGE
                     "
     CDS             11965..12330
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MQEDLRYMSSEKYYEGVIVDVEGGAVTIDLKGRLGQFKIPNRMLI
                     TDYNPQVGQEVGFMLSNPEVLRPEPNEEYIRKMNGQRKIEEKKKFENLTRLEKSILEKT
                     KELEELEKKIKELGLDI"
     CDS             12356..12814
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_11"
                     /sec_met_domain="GRDB (E-value: 1.9e-18, bitscore: 56.8,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKLTTVPGLQSEIYVPITPPPVWTPVTKPLNEMVIALATAAGV
                     HLKTDERFNLAGDTGFRMVPDTATPDDLMVSHGGYDNSDVNRDVNCMFPIERLHELKAE
                     GFIKDVAPMHYTFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAG"
     CDS             12836..13087
                     /locus_tag="ctg42_12"
                     /transl_table=11
                     /translation="VIVQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGE
                     PHNVEMQTGILKATLEQLVSIPSAGKIVPLPFEYHAAI"
     CDS             13218..13976
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_13"
                     /sec_met_domain="Proline_reductase (E-value: 1.2e-66,
                     bitscore: 215.2, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKILRRLVIKPFSINEVKFGKRFGIKGDVLEIVEEKIEELKAS
                     NDLITNIRLEIIKPGDYDREINTIMDIIPISTKVLGGLGEGITHTLSGVYVMLTGVDED
                     GRQMHEFGSSEGNLSEQMIFGRCGTPDVTDYIIHMDVTIKGGLPFDRNLPNACFKACDD
                     FIQEIRAVLKSIDGRLADGSHEFLDKISPGKKKVVLVKQVAGQGAMYDNLLFAQEPSGF
                     EAGTSVIDMCNMPMILSPNEYRDGILRALV"
     CDS             13988..14455
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Proline_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_14"
                     /sec_met_domain="Proline_reductase (E-value: 6.4e-31,
                     bitscore: 97.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIGPSTKETSLHMFRDPLVKVLGEDTDIDFAGIVVVGTPDDNKY
                     KNLVGQRAAAWCEAMRADGVILSADGWGNSHVDYANTFEEIGKRGIPTVGVTFNGVQAK
                     FVVTNKYMDTIVDINKSESGTETEVVGENNVDIIDARKALVFLKLKMRKAK"
     CDS             14482..15489
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Pro_racemase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_15"
                     /sec_met_domain="Pro_racemase (E-value: 2.5e-131, bitscore:
                     427.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFSRSIHAIDSHTAGEATRIIVGGIPNIKGKNMPEKKQWLEDNL
                     DYLRTAVMLEPRGHNDMFGSILTQPTVEEADYGIIFMDGGGYLNMCGHGTIGAMTAAVE
                     TGIVKVTEPITKVVQEAPAGIIRGEVLVENGKAKKVSFQNVPAFLYKRDQEVELPGFGK
                     IKFDISFGGSFFAIVKADQIGLDIVPENAGKLNSLGMQLRDIINAEIPVQHPELPHIKT
                     VDLVEWWSETDTPGATYKNCVVFGQGQVDRSPCGTGTSAKLATLHAKGEFKMGDKFFYE
                     SILGTIFEGEIVGTAKVGEYDAVIPQISGSAYITGFNHFVIDDEDPLKHGFILK"
     CDS             15628..16524
                     /locus_tag="ctg42_16"
                     /transl_table=11
                     /translation="MIVTILLWIFRICIAGTGILMVADIAKHKENLGNTSGAQVGKSIF
                     IGFITNFGDTLGIGSFGPIVALFKLLKVDISDKEIPGTLNVSCAIPVLVEALIFTSAVE
                     VEPITLVALLFAAALGSYIGAGIISKMDEMKIQIVMGVCLFVAAIIMLVTHPALGLFEA
                     GGTAKGLTGIKLIIGIVVNFILGALMTAGVGLYAPCMALIFLLGMDVKAAFPIMMGSCA
                     VLMPTCSVKFIKEQTYNKLVSILIAIGGVVGVFIAYKFFSSVDVNKLKFVIIAVILYTA
                     YTMFSKGMKTKKARAMQ"
ORIGIN
        1 tcaaggatat ttattcattg aaaacaaagc ctcaattgga aaagggagtc tataatgttc
       61 ccatagtttt gaggaatttt gagttaacag aacaaaattc aatgggaaat aatgctatca
      121 tgagtaaggc caaactaatt gtagatgaaa gtggaaaaat aagactaagg tttaacctaa
      181 gaggtctgta ctttatggga gcatatggtc atttgacgaa tttgtggtat tataataata
      241 ctaaggaaga aaatgttgat aaaagtcact tggagtacct gggggaattg accagagtaa
      301 aggtattaaa aactaagaat gaactagatg cagagggtaa tttaagagat tttctaaaaa
      361 gtgttgaaat aaatatagac aagcatgtag ataatcccaa aagatatctt aaagtaaagg
      421 ttgatgcgat ggatatgctt aatggtataa atccatatga aaatttggat gaaaattcta
      481 cgtcacctaa tgccattctt acccttgact ataggtttat tgaaaaagat cctacaaaca
      541 atgaaaatcc gtatagccaa ggtgacgagt tagaacaagc taaaaaagaa gccaaaataa
      601 gtattgataa tttgtcaaaa ttagactcaa atagtaaggc taaatacaag gcagatatag
      661 acaatgccga gtcaaaagaa aaaatcaacg aggtactaaa agaagcaaag tatgccaatg
      721 ataaaattga aaaggatatt gataaatcga aaaaagatgc aaaatctgaa atagacagat
      781 taacagactt atcaagtgat gaaaaaacta attttaaaaa taagattgat tcatctactt
      841 caaaagagtc tatagaagct attgtcaagg aggcaaaaga cctaaacaag aagaaaaagg
      901 ataaaaataa gaaaaaatca gaaaaaatac agaggttgtc aggtgataat agatatgaga
      961 cttctgttga ggtaagcgaa aaaaacttta aatctgtaga tacagttgtt cttgcaagtg
     1021 gtcaaaatat tgctgatgcc ctagttgcat catcatatgc cgatattgaa gaggccccaa
     1081 tactattgac aaataaaaat tctatttcag atgaagttct tgatgagatt gagaggttaa
     1141 aggcggataa ggtagttatt gtaggcggtc aatcctctat ctccagtagt gttgagtcta
     1201 gattaaaaaa agaagatata aaagtaacac gtatatcagg aagggatagg tttgacactt
     1261 ctgataaact atcccaggaa gttagtagac tatctaaaaa atccagccag gctatcctgg
     1321 taaatggata taagaatata gatgctcttt cagtttcatc tctagcaaca aaagaagacc
     1381 tacctatatt attgaatggt agaaatactt taaatatgtc tgtaaaaaat aggttaaaac
     1441 agatgaatgt gaagaaggta tatataattg gtggcaacaa ttccatatca agtgacgtgg
     1501 aaaaagagtt gaatagaatg caaatatcag ttgtaagatt atctggaacg gataggtatg
     1561 aaacatctgc caatattgcc aagtatgcct ataaggactt taatgaggct atagtagcca
     1621 gtggtgaaaa tcctgttgat gcattagcag ctagtacact tacagggaaa aaggaagccc
     1681 caatactatt gacaaataaa aataagattc caaaatcaat taaaaaaatt attgaagata
     1741 tggatatagg aaagattaca atagttggcg gtgaaaacag tattactgat aatgtgatag
     1801 atgatatgga ggacatgtta taagttttta aaactttgat acttccatat gccattttaa
     1861 aaagcaaaat aggaaaaaag atttatttca ataagggctt aagacccata ttgatttaaa
     1921 tcttttttgt tatatatcaa attataggat ttataaaatt ggaggttgat agttcatgag
     1981 tattaagaaa aataaattta cctttatttg tgctcttatt ttaatcttga tgcctattac
     2041 atttttggct tgtaagcagg atgaaatagt tgcaagtact gataaatttg atgttaggct
     2101 aagtgaagtt aatgataata taaagttggc aaaatttgaa tataattcta tttttggtga
     2161 tgatagctgg aagagtgttg tagtttcatc tgacggaagt acggaacaat ttaagaaaag
     2221 cgttatagat tatttaataa tgagtcatta taaggatgaa gaaaataaaa agaatgggta
     2281 ttcatattca gaagaggaat taaatgatat gcttgacagt gctaagcaaa atattgagga
     2341 ggataaaata aaaagcaatg agtataagag tctgaatata gatgatcacg tactaaaaaa
     2401 atatatcaga gacaagatga ttgagaacaa gaatcaagaa gaatttaata aaagggtcaa
     2461 aatcaaagag gaagatataa aaaaatatta taaagacaag ataaatgaat ttaaagaaaa
     2521 ggaatttgat tgttatcaaa tttggataaa gaatcctaat gataaaatta aggcagaaaa
     2581 tgcttataaa gacttaaaaa agggcatgga tttttctact gtagtcaaaa agtattcaga
     2641 agatgaaaac agtaagaata aggggggcta cattggaaaa atcaaaaaag aaaatttgat
     2701 tccggaatta cgtgaaaagg ctttgataat gagggataaa gagtatactg gagtagtaaa
     2761 aagcaaggat ggatatttta taataaaaat tgataaccaa agaaatttaa caaaaacatt
     2821 ggattcttgt agaacaaaaa taaaagatga tttgttagaa aaattatatc aggaaaataa
     2881 taaaaagata attaatagaa ttggtgtgaa atactataag gacaatataa agaaaataaa
     2941 gatacaattg tagggatttc tatcatagca agtattttga ataactttct cgtaagtgta
     3001 acatatgtat tgacaactaa gatattgaca actaagattt tcaataagat atttacaatt
     3061 tataattgag gtgctaaaat taagttgtat ttatgtaggt aaaataataa aacaaatgga
     3121 tttattatag cctaaataat agagattata cttagtagga gcgtgaatag tatgaataga
     3181 aaagtacaaa aatttattgt agcacttgga ttagtgggaa ctcttggatc atgttcattt
     3241 gcagatgtgg ttgtagatgt gtctgatgcg agttcaaaag gtaaagttgc aattgataac
     3301 aacccagtta tcaatgaaca ggcgagtgac ggaagtatta aagttgttga tactaaaaag
     3361 ttgtccgtag agaggatagc aggaaagaat aggtatgaga catcttacaa aataagtgag
     3421 gcactaggtg aatataaaaa cattgtaata gcaagtggag aagatttccc agatgccttg
     3481 tcagcgggtt tattggctag tcatcttaaa gcaccaattt tattgactga aaaaaaatca
     3541 gcagacaagt atttacttga tactttaaac agacataaaa atcagcagta ttacatagtt
     3601 ggtggtgaaa atagcgtatc taaaaacaca aaggaaagca tacaagcatt ctcaaaagat
     3661 agtattaaaa ttttagcagg caaaaatagg tatgaaacgt caagtaaagt tgcttcaatg
     3721 atagataaag atatctttgg aaatgattac gccacagata tgcttgcagt ttataatggg
     3781 gaagatttcc cagatgcctt agctgcgact ccttttctat atcaaaacaa caacgataaa
     3841 aagactcgta ctccaataac tcttgcatgg aatccaaagg ttaaagtaga ttcagatatt
     3901 ctgcaaattg tattcggtgg cgagtcattc cttccaaggg gcaatgaaaa gcttagatta
     3961 gctggttcaa acagatacaa gacatctgtg gaagttgcaa aggcatttaa aactgttcta
     4021 aataaagata tagatacagt gataattgca tcaggtgaag actatccaga tgccctgtca
     4081 gcaggtccgc ttgcatctag caagaatgca gcaattctct taacagaagc taagggatta
     4141 aatccagatg taaagaaata catagaagaa acaaagtcaa taaagaacgt aataatagta
     4201 ggtggagaat caacagtatc agcccaggtg gaaaaggact tagctacaat agcaagataa
     4261 taaaagttta gagagctata tataagacct taataatacc gaagattggc agtaagtcgt
     4321 cttcggtatt ttttatttaa aatatacatt aaaaataggg gattattttc aataagatat
     4381 ttacaattta taatcgaggt gctaaaatta agttgtattt atgtaggtaa aataataaaa
     4441 caaatggatt tattatagct taaataattg agattatact tagtaggagc gtgaatagta
     4501 tgaatagaaa agtacaaaaa tttattgtag cacttgcatt agtgggaagt cttgggtcgt
     4561 attcttttgc agatgtggtt gtagatgtgt ctgatgcgag ttcaaaaggt aaagttgcaa
     4621 ttgataacaa cccagttatc aatgaacagg cgagtgacgg aagtattaaa gttgttgata
     4681 ctaaaaagtt gtccgtagag aggatagcag gaaagaatag gtatgagaca tcttacaaaa
     4741 taagtgaggc actaggtgaa tataaaaaca ttgtaatagc taatggagaa gattttccag
     4801 atgccctatc atcaggaata ttagctagtt atctaaaatc accagttata ttgactgaaa
     4861 agaactcagt aaatccatat ttgtattctg ctttaaatac acacaagaat caaaaatatt
     4921 atgttatcgg tggtaaaagt agtatatctg aaaaagtcat ggaagatatt aaacactttt
     4981 ctccagacct gactagcagg atttctggta aagatagata tgagacagcc ggactagtta
     5041 cttctaagat aattagagag atatataata gctatggtta tccagataat ttagcggttt
     5101 atgatggcag tgattttgca gatgcgatgt ctgcaactcc ttttatgtat cagtatgaaa
     5161 gaaataaaga aaaagaaaaa ccagttaccg ttccgttgcc aaagggttat aagattgatc
     5221 atgataagtt agaagttgta ttcggtggag agtcattcct tccaaagggt aatgaaaaac
     5281 ttagattagc tggttcaaac agatacaaga catctgtaga agttgccaag gcatttaaaa
     5341 ctgtcttaaa taaagatata gatacagtga taattgcatc aggtgaagac tatccagatg
     5401 ccctgtcagc aggtccgctt gcatctagca agaatgcagc aattctctta acagaagcta
     5461 agggattaaa tccagatgta aagaaataca tagaagaaac aaagtcaata aagaacgtaa
     5521 taatagtagg tggagaatca acagtatcag cccaggtgga aaaggactta gctacaatag
     5581 ctagataata aagactgaga tacaagtcaa aagacattaa aaataccgaa gatggggaaa
     5641 aatcatcttc ggtatttatt ttataaaaat tttagttgta taagactatc tcttctgtcc
     5701 atccttcaag aatcttatct tttcaattcc catagtttct aggattgtgt cagtctggtg
     5761 atgaactggt atacccatct taggagcaac acccataact gtgtttgtac agtcagtaca
     5821 gttagagatt agaacttcct gagctccagc cttcttaagg ttaagcatct tagcagcctg
     5881 tccaggacag tgtccaggtc tttcacactt aagtgcgcca cccttacctt cgattgcctg
     5941 cttacacttt tcaacgccta ctacttgaga acccatgtag ccggctattt ctctaagtct
     6001 agcttcgtta ccaccacaag cacatactag aagacccatc tttggagctc cctttggata
     6061 tggcttagta actaatatac cacctgtagc cttcttagtg tagtcatcta cagtagtgct
     6121 agtaccagtg aatggtccac ccattatgat ttcgccgtat tcaccatact tgaatattcc
     6181 accagctcta tctataaggt ctccaactct agtaccgatt ggaacgttca taaatatttc
     6241 tagtgagtta gcagtattta agtaaccagc aactgttata tttttttcta ttaatggctt
     6301 taggtcatca acagcatctg ctatagcgca catagtttca gagtttatta caacagcgtt
     6361 tgcagctgat ggtaactggt cagtatcaag ttcgatacct agacattctc taactacagc
     6421 tctttcttca cccattgggt acatatttgg catagcttcg attctgattc tctcatcatc
     6481 tataattgct tcaagagcct ttatttcctt tggatgtatt tcctttagag cgaatacacc
     6541 atgagcagca ttagtagctt ccatacatag tttcatacct ctaagtagtt tttcaggttc
     6601 taatagtaac tggttcatat tgtgagaaag tattggttca cattctgcag cgttacatag
     6661 tacataccct gtaccaccaa gatcagtacc aagcttaacg tgagctggga aacctgcacc
     6721 accaagacct acaatacctg cattctttac agtttcagct attgtagcac ctttttcgat
     6781 ctttacatag tcttctcctt gaacatcgtt tgcttcaatt atgatttcat cttcagtaat
     6841 atcaacaacc ttaccatcaa cgctggcatg taaataagca cctagtcctt caaatgtacc
     6901 aactagttgt cctcttttaa cttcatctcc aaccttaaca actggagtgt tcttagcgcc
     6961 aatattctgc tttaataata aatgaatcat cttagacata atttgccccc ttaaaaaata
     7021 atagtagtgt tattagctag taatttagta atgtttttgt tttgctagta aacagattga
     7081 atctatcatt ttaaaagtat gcttagcgga aaaatccact cttataagtg tattatacca
     7141 tacaggtaca aaataacaag tacttgtata aaaagatagg tataataaat atttatttac
     7201 tatataaaaa ataagtatag cggagatact gtttgaaaaa aggtgtaaat attaggtata
     7261 gagtaaaaaa ataatttact tggatgatat atattgattt cacaaaaagt ctaccaatat
     7321 gtgatataat ctaatctata gataaaagtt gtgctaatca atgagaaaga gaggtggttg
     7381 taattgttca aagttccttc aaaagaaaat ttagaagatg ttatgcaaaa agactttgtc
     7441 acagctgatg aaaacctcaa agttgaggat gtatttgaag acttaattac aaataaaaag
     7501 acggttataa cggttgatag gaataaaaat atgattacag gctatatagg tatactggat
     7561 atagccaatc ttgttcaaaa aaagggaaca tcatacaggc aagccgtatt aaaagatata
     7621 gtaaaaaaag aatttataat gatagacagg agctataatt ttaggaccta tactaagttt
     7681 ttggaagatg aaaactatat gtacatagta gttgaggatg acagtgtcgt aggatattta
     7741 aatgcctact atgtaaaaca aaataactat cctttcctaa atgaagaatt tactacctta
     7801 aagcatataa taaaccaggt gaatgagggc ataagtgcca tagaccgtga tggggttgtg
     7861 atattatgga ataagtttat gcaaaaaagg tacaacatta catctgatga gatagttggt
     7921 aggaaaatga gtgactatct agtcgacaca atatcggaga gagtacttac aactagacag
     7981 gccatgagcg atgtatacta tacaaaaaag aatatggcag gcactgattt atatggagtt
     8041 gttcatgcct tcccagtatt tcataaagaa gaatttgtag gtgtagtttg tacagaggta
     8101 gatgtaaccg atgccagcaa gctttctaag gagcttgaac ttacacaaga aaaaataaag
     8161 taccttgaag aagtaaaatc tctttcaata ggtgagtttg acaagatttt aggcaagagt
     8221 taccccttag aaaaggctaa aaacatggca aagcaggtag ctaaaaccaa ttcatcaatt
     8281 atgataaatg gagaaagtgg tactggtaag gaagtttttg caagggccat acataagtat
     8341 agtgagagag aggggacatt tatacctgtc aactgtagtg ctataccaca ggaattattt
     8401 gaaagtgagt tttttggata tgaacctgga gccttcactg gagctacaaa aaatggtaag
     8461 ccgggtatat ttgaactggc aaataaagga accttatttt tggacgaaat aggggatatg
     8521 ccttataata tgcaggctaa gcttcttaga gttcttcaag agagggagat aatgagggtt
     8581 ggcggaaatg agattataaa aattgatgta agggttattt cagcttcaaa caaagaccta
     8641 gctgctatgg tcaaggaaga gacatttagg gaggatctct actatagatt gaatgtcgta
     8701 gagataaacc taccatcact tagggagagg ggtggagatg ttgcaatact aatatatgaa
     8761 tttttggaag agcagtgcaa gataaataat aaaccttttt tgaaaatttc aaaagaagcc
     8821 ttggatatgc ttcagagata tgagtggaag ggaaacataa gagaactaaa aaatactatg
     8881 gaaaatatgg tcgttttatc taacagagac actttggaag ttgaagatat acctgtttat
     8941 attagacata aagttgaaag caaagaagat aaggagacta tgtacccgat ggatcttaat
     9001 atggctgtcc aaatactaga aaaaaacaag atacaggaag ctttggaaaa aacatctggt
     9061 aataggtcta aggcggcaaa aattttgaat atacctagga caacattgta ttataaaatg
     9121 gatcaatatg gaattaggga taaatagata taaaaaatac aagtaaaaaa cttttgaagt
     9181 tacagaaaaa aatcttgtaa gtgcatatat atattaaaat ggcaaaagtg tataaaaaac
     9241 agacatatgt tcaaaaaaca gacaaatagt tgtgtagttg taaaataagc ctataaacaa
     9301 gcctataagc ggtgttggag ggcttatttt tttgttttag tgcattttac taattaaaaa
     9361 atgaaaaagt tgtcggttat tagacatata gctttatggt attgtttata tagaaaaact
     9421 ctattaatat aatttggtat atagctaaac ccacttaaat aaacaaagca taatattaaa
     9481 ataaatgaaa tttacactgt ttcgaattgt tggcatggat attgctgtag ttatgtcagt
     9541 aatgtttttg ttaagtgtat atttgtgttt aatattgata ttgttataac ttaatcagta
     9601 ttatagaata caaagccact ttattctata tagctaagta aaatgtatat aattagtcta
     9661 aattaaacat gactattaat tgaaaaatat gcatgataga aaaaaactat caacttacat
     9721 attgaaaatt ttatgaatct attatatatt atgaattaag gaaagtgata tcgataacaa
     9781 attaagaata gactatagag ttgtttactg ttgatattaa caccttaaga acctttagta
     9841 gctaaaggtt ggatgcagaa caaaaagtaa tatagttgtg agtggtttgt ttgtattagg
     9901 gtacattgat aagatgtgtc gcaattttta aaaatcattt caacatattc aactttgtta
     9961 taaattaaat tttaactata tttaaggagg attttttgct atgtcaataa ctaatgaaac
    10021 agcaaaagcc catgctaatg atcctgcagt ttgttgctgt agatttgaag ctggtacagt
    10081 agttgaagct gctaatcttg aagatccagc aatattccca gacctaatcg attctggatt
    10141 attggaaatt cctgagaatg ctttaactat aggtcaggta ttaggagcta agttaactca
    10201 gactctagac gctcttacac caatgactac tgaaaacaca gaaggatatg ctcttgaaag
    10261 tgaagaagag gaagaagtag ttgaagaagt tgctgaagct cctgtagctg cagttgctcc
    10321 tgttgctcag gcagacggag ttctaagaat acagatagct gaaggtaagg gaatcaacct
    10381 tgaaatacca atgggtgcta taggtggttc tggtgttgct ccatctgctg gtgttgttgt
    10441 tccagttgcg gaagctggtg cagttgcaga tgaagtagaa gaaactaagg ttcttagaag
    10501 tcttactaag aaacactaca agattgataa ggtagtattc ggtgaaaaaa ctgaaatcaa
    10561 aggaactaca cttacaataa gaaatccaga agaaatatgt gcagaagctg ctgctactga
    10621 agaactagta ttagatctta agttagacat aataactcca gatagatata atgaatattc
    10681 agaagcaatt cttgaccttc agccaatcgc aactaaagaa gaaggagaac ttggtgaagg
    10741 tgtaacaaga gtgcttgatg gagctgtaat ggttcttact ggtactgatg ctaacggtgt
    10801 tcagataggt gaattcggtt cttcagaagg tgctatggat acaacaatga tgtggggtag
    10861 accaggtgct gctgaatttg gtgaaatatt catcaagggt gaagtaacta taaaggctgg
    10921 tactaacatg gaaagaccag gacctctagc tgctcacaag gcatttgact atgtcactca
    10981 ggaaataaga gaagctataa aggctataga agatgaatct ctagtagttg atacagaagt
    11041 aatcaaccag tacagaagag caggaagaaa gaaagttgtt atagttaagg aaataatggg
    11101 tcagggtgca atgcacgaca acctaatatt accagttgaa ccagttggta cattaggcgc
    11161 tagaccaaac gttgacttag gtaacgttcc agttgttctt tctccactag aagtattaga
    11221 tggtggtatc cacgctctta cttgtatagg acctgcttct aaggaaatgt ctagacatta
    11281 ctggagagag ccattagtta tgagagtaat ggaagatgaa gaactagacc tagtaggtgt
    11341 agtattcgta ggttctccac aggctaactc tgaaaagttc tatgtatcta gaagactagg
    11401 tatgttagta gaagctatgg aagtagatgg tgctgtagtt acaactgaag gatttggtaa
    11461 caaccatata gacttcgcat cacatatcga acagataggt atgagaggta ttccagtagt
    11521 tggtgtatct tactgtgcag tacagggtgc tctagttgtt ggtaacaagt acatgactca
    11581 catggttgac aacaacaagt caagacaggg tatagaaaac gaaatacttg aaaacaactg
    11641 tttagctcca gaagaagcac acagaatagt tgctatgtta aagaatgcta tagaaggcga
    11701 agaagttaag ccagctgaaa gaaagtggaa taacaacgtt aagttaaaca acatagacgc
    11761 aattgaaaag gctctaggta tagaaattcc tctagaaaag aacgaaactt cacttaacat
    11821 gactagaaag agaagtcagt tatacgaaag agcagacata gaagctggta tagtagaaga
    11881 tacttatact ccagttgaag gagaataatc taatatagcg tatagttttg ttcaaaacct
    11941 attacatgaa aggataaaaa tagtatgcaa gaagatttaa gatatatgtc atctgaaaaa
    12001 tactatgaag gcgtcattgt agacgttgaa ggtggcgcag tcacaattga ccttaagggt
    12061 aggttaggac aatttaagat accaaataga atgcttatta ctgactataa tcctcaggtg
    12121 ggtcaagaag tcgggtttat gttaagcaac ccagaggtat tacgtcctga acccaacgag
    12181 gaatacatta gaaaaatgaa tggtcagcgt aaaattgaag aaaagaaaaa atttgaaaat
    12241 ctgactagac ttgaaaaatc aatcttggaa aaaacgaaag aattagaaga gcttgagaaa
    12301 aagataaaag aactaggatt agatatttaa attaatttga agggagaaat tacaaatgag
    12361 tcgtaaactt acaacagttc caggacttca atctgagata tatgttccaa taacacctcc
    12421 tccagtttgg actcctgtta caaagccatt aaacgaaatg gtaatagcac ttgctactgc
    12481 agctggtgta catttaaaga cagatgaaag atttaaccta gctggtgata ctggattcag
    12541 aatggttcca gacacagcta ctccagatga ccttatggta tctcatggtg gatatgacaa
    12601 ctctgacgtt aatagagacg ttaactgcat gttcccaata gagagacttc atgaattaaa
    12661 ggctgaagga tttataaagg acgttgctcc aatgcactac acattcatgg gtggtggtgg
    12721 taaccagcat gtcttcacag aagaaactgg tccagcaatc gctgctaagt taaaagaaga
    12781 gggtgtagat ggcgttgtca tgacagctgg ctgaggtact tgccatagaa ctgccgtgat
    12841 cgtgcagaga gcaatagaag aagctggtat accaactata ataatagcag ctcttcctcc
    12901 agtagttaga cagaatggta ctccaagagc ggttgctcca ttagtaccaa tgggtgctaa
    12961 cgctggtgaa ccacacaacg tggaaatgca gacaggtatc ctaaaggcta cacttgaaca
    13021 gttagtatct ataccatctg ctggtaagat agttccatta ccatttgaat accacgcagc
    13081 aatatagttg aatatttaac attataggtc ttgaacttat ttagtgttta gcttataatg
    13141 acagtaagcc catcctctat aatctaatga tataggggat gtcggtttac ttagtttaat
    13201 taaaggtggt aatgtatatg gaagaaaaga ttttaagaag acttgtaata aaaccgtttt
    13261 ccataaacga ggtgaagttt gggaaaagat ttggaatcaa gggtgatgta cttgaaatcg
    13321 tcgaggaaaa gatcgaagag ctaaaggcat caaatgactt gattacaaat attagactag
    13381 aaatcatcaa acctggagac tatgatagag aaatcaacac tattatggat ataattccca
    13441 tatctaccaa agttcttgga ggattgggtg aaggtataac tcacacactt tctggtgtgt
    13501 atgtaatgct tacaggagtt gacgaagatg gaagacagat gcacgaattt ggttcatctg
    13561 aaggaaatct tagtgaacag atgatatttg gaagatgtgg tactcctgac gtgactgatt
    13621 atattataca tatggacgtt acgattaaag gtgggcttcc atttgacaga aatttaccaa
    13681 acgcatgttt taaagcttgt gacgatttta tacaggagat tagagctgtc cttaagagca
    13741 tcgatggaag acttgccgat ggttctcatg agttcctaga taagataagt cctggtaaga
    13801 agaaggttgt tttggttaag caggttgctg gtcagggtgc aatgtatgac aacttgttat
    13861 ttgcacagga gccaagtggc tttgaagctg gaacatcagt aatagatatg tgtaatatgc
    13921 ctatgatcct atctcctaac gaatacagag atggtatctt aagagcacta gtttaggggg
    13981 tgagactatg ggtataggtc cttcaacaaa ggaaacatca ttacatatgt ttagagatcc
    14041 actagtaaaa gtattaggtg aagatacaga tatagatttt gcaggtatag ttgtagtcgg
    14101 aacacctgat gacaacaaat ataagaactt agttggccag agagctgctg catggtgtga
    14161 agctatgaga gcagatggtg taatccttag cgctgatggc tggggtaact cacacgttga
    14221 ctatgcaaat acatttgaag aaatcggtaa aagaggaata ccaacagtag gtgttacttt
    14281 taacggagtt caggcaaaat ttgttgtaac taataagtat atggatacaa ttgttgacat
    14341 caacaagagc gagtctggta cagagactga ggttgtcggt gaaaacaatg ttgacataat
    14401 agacgcaaga aaggctttag tcttcctaaa gcttaaaatg cgtaaagcaa aataattaat
    14461 aatacactgg aggtactaat tatgaaattt agtagaagta ttcatgcaat cgattctcac
    14521 actgctggtg aagcaacaag aattatagtt ggtggaatcc caaatataaa gggaaaaaat
    14581 atgccagaaa agaagcagtg gctagaagac aatcttgatt atttaagaac tgctgttatg
    14641 cttgagccaa gaggacataa tgatatgttc ggttcaatac taactcagcc tacagttgaa
    14701 gaagctgact acggtatcat attcatggac ggtggcggat accttaacat gtgtggacat
    14761 ggtacaatag gtgctatgac tgcagctgtt gaaacaggta ttgtaaaagt tactgaacct
    14821 ataactaagg ttgttcagga agctccagct ggtataatca gaggtgaagt actagttgaa
    14881 aatggtaagg ctaagaaggt atctttccag aacgtacctg cattcttata caagagagat
    14941 caggaagttg aactaccagg atttggtaag atcaaatttg atatatcttt cggtggaagt
    15001 ttcttcgcta tagttaaggc tgaccaaatt ggtcttgata tagttccaga aaatgcagga
    15061 aagttaaatt ctttaggtat gcagttaaga gacatcataa atgcagaaat accagtacag
    15121 catccagaat taccacacat taagacagta gacctagttg aatggtggtc agaaactgat
    15181 actccaggtg caacttacaa gaactgtgtt gtatttggac agggacaggt tgacagatct
    15241 ccatgcggaa caggaacaag tgctaaactt gctactctac atgctaaggg tgaattcaag
    15301 atgggagaca agttcttcta tgaatcaatc cttggtacaa tatttgaagg tgaaatcgta
    15361 ggtacagcta aggttggaga atacgatgca gttatacctc agatttcagg ttctgcatat
    15421 atcacaggat tcaatcactt tgtaatcgac gatgaagatc cacttaagca tggatttatc
    15481 ttaaaataat agtattaaaa taagcataca tctcctttta ggaggtgtat gcagtaataa
    15541 cataattaaa tatgacgttg ataaatcgcg tttgcctgcg ataaataaat tgagctattt
    15601 tacaattaat tttgggggta ataaagtatg atagttacta tattattatg gatattcaga
    15661 atatgtatag caggtactgg tatactaatg gtagcagaca ttgctaagca taaagaaaat
    15721 ttaggtaaca catcaggagc tcaggttgga aaatctattt tcataggttt tatcactaac
    15781 tttggtgaca ctcttggtat aggttcattc ggtcctatag ttgctctatt caagttatta
    15841 aaggttgaca tcagcgataa ggaaatacca ggtactctaa atgtatcatg tgctattcca
    15901 gtattagttg aagcacttat atttacatca gctgttgaag ttgagcctat cacactagta
    15961 gcattattat ttgcagcagc gcttggttca tacattggtg ctggtataat atctaagatg
    16021 gacgaaatga agattcagat agtaatggga gtttgtctat ttgtagcagc tattataatg
    16081 cttgtaactc acccagctct tggattattt gaagcaggtg gtacagctaa ggggcttaca
    16141 ggaatcaagt taataattgg tatagttgtt aactttatac ttggagctct tatgacagca
    16201 ggtgttggtc tttacgcacc ttgtatggcc cttatattct tactaggaat ggacgtaaag
    16261 gctgccttcc ctataatgat gggttcttgt gcagtactta tgccaacttg ttcagttaag
    16321 tttatcaagg aacagactta caacaagcta gtttctatac ttatagctat aggtggtgtt
    16381 gtcggtgtat tcattgccta taagttcttc tcaagtgtag atgtaaataa gttgaaattc
    16441 gttattatag ctgttatact ttacactgct tacacaatgt ttagtaaggg tatgaagact
    16501 aaaaaagcaa gagctatgca gtaagcttag gcatttttaa gcgaattggt tttaatttaa
    16561 tagtaaaaaa atccctctag gattttctag aggga
//
