LOCUS       NC_008525.1            22094 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_008525.1 Pediococcus pentosaceus ATCC 25745, complete sequence.
ACCESSION   NC_008525
VERSION     NC_008525.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:12:00
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 287575
            Orig. end    :: 309669
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22094
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[297575:299669]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12094
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..22094
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22094
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             789..2123
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_237"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.6e-59, bitscore:
                     197.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 2.5e-14, bitscore:
                     50.2, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYDVVIIGAGPGGLGLAYPLKEAGLEVAVVEENLWGGTCPNRG
                     CDPKKVLLAAIEAKKQNQYLLGNGIKNETQIDWPALMQFEKTFTDPVSRSSRSGLTDAQ
                     IDVYDGHAEFIDHHTLKIDQTTITSEKFVIATGQRPSRLTNIENQEMMQTSTDFLKMDH
                     LPNELALVGGGYIAFELAMIASGAGAKVHIIHHNQRPLKAFPKAYVDDLVDQLKTQGVE
                     VHLGIDLKRVEPKDERFELSDGQGFKQIVDQVFVTAGRKPNDDSLNLEKIGVQTDRGGI
                     VVNEYLETSVDNIYAMGDVVSKALPKLTPVSGFEARYLAKKLTNATQAAIDYPAIPTVV
                     YGMPKLAKVGVELDEAQQHPEQYEIKTAEMTEWFTYRRLQDPFAKISVIHEKSSGKIVG
                     AITMSSEAEHLINDLTMIINQGGLVDQINNQILAYPTEASDLGYM"
     CDS             2180..3340
                     /locus_tag="ctg1_238"
                     /transl_table=11
                     /translation="MEFVGVLVLILVLTLLAGHFAQRMGFPAVVGQLLVGIILGPGILG
                     IIHSDELISVFSEIGVIILMFLAGLESDLKMLKKYIKPALVVAILGVVLPIVLVGGASL
                     LFGVHPMEALFIGVIFSATSVSISVEVLKEYHTLNTKEGATILGAAVADDIIGVLLLGV
                     MIALTSSKSGSNSNVGMAIFYQVLFFIGVYVIGKWVVPMLMRLSDQLFITASRPVMSII
                     ICLGLAWLADVAGLSGAIGAFFAGVAVSLTDEDDEINESIEPIGYAIFIPVFFVSVGLS
                     MNFDGLQTVLGLIVVLTILATITKLFGCGLGARMSGFDLTSSGVIGAGMISRGEMALIT
                     LQIGYGEHLMSETYYSAIVLVIVLVTLIAPFILKDAIKKNKAATHA"
     CDS             3480..6905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_239"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.9e-14, bitscore:
                     48.7, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="HMGL-like (E-value: 7.2e-33, bitscore:
                     111.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 6.6e-69, bitscore:
                     228.3, seeds: 434, tool: rule-based-clusters)"
                     /sec_met_domain="CPSase_L_D2 (E-value: 2.6e-76, bitscore:
                     252.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRILIANRGEIATRIIRATHELGKTAVAIYAKADEFSMHRFKAD
                     EAYQVGEDSDPIGAYLNIDDIIRIAKENNIDAIHPGYGFLSENAVFARAVEAAGIKFIG
                     PRPELLEMFGDKLQAKNAAIKAGVPTIPGTEKPVKDVDDALNFAEQFGYPIFVKSAAGG
                     GGKGMRIVHHQQEMREAFKMAQSEASSSFGDDEIYLERYLVDPIHIEVQVVADEHGEMV
                     HLYERNSSIQRRHQKIIEFAPAVGISATVRDQIRKAALKLLKSVDYSNAATIEFLVEGN
                     QFYFMEVNPRIQVEHTVTEEVTGIDIVQTQIKVAEGQRLHEEIGVPQQAQIEAVGVAIQ
                     ARITTEDPMNNFIPDVGRIQTYRSPGGTGVRLDAGNAFAGAIVTPHYDSLLTKAIVHAP
                     TFDEALVKMDRVLNEFVIAGVKTNIPFLKKLIHHPIFRSELAPTNFVDETPELFDLKAE
                     TPVVTQLLSYIANTTINGYPGLEKQNPVVLTRPVRPHFEAQVPHENAKQILDSKGPDAM
                     INWLLKQKQVLLTDTTMRDAHQSLFATRMRTKDMVEIADQVQKGLPNLFSAEVWGGATF
                     DVAYRFLGEDPWVRLQQLRAKMPNTMLQMLLRGSNAVGYQNYPDNAIDEFIRLAAKNGI
                     DVFRIFDSLNWVPQLEESIQRVRDNGKVAEAAMAYTGDILDTNRTKYNLKYYVDLAQEL
                     QAAGAHIIGIKDMSGILKPQAAYALISELKNHLDVPIHLHTHDTTGNGIFLYSEAIRAG
                     VDVVDVATSALAGTTSQPSMQSLYYALSNNQRQPDLDIQKAEKLDEYWAGIRPYYEGFG
                     TQLNGPQTEIYRIEMPGGQYTNLRQQANAVHLGKRWDEIKEMYATVNQMFGDIPKVTPS
                     SKVVGDMALFMVQNDLTPEMVMNDKGQLSFPESVVNFFRGDLGQPAGGFPKQLQKMILK
                     EQAPLTVRPGALADPVDFDQVRKQATKVLGHQASDEEVMSFIMYPDVMTEYVQRQNEYG
                     PVPLLDTPIFFQGMHIGQRIDLQLGRGKSVIIVLREISEADEAGQRSLFFDINGQSEEV
                     IVYDVNAQVTKAKKIKADPTKAEQIGATMAGSVIEVQVEAGQKVQQGDNLIVTEAMKME
                     TALRAPFDATIKKIYATPEMQIETGDLLIELEKE"
     CDS             6910..8085
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_240"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.6e-64, bitscore:
                     214.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFSKRANQVSPSATLAVSTEAKKMQAAGIDVVNLSTGEPDFATP
                     KAIIKAAMESMESGKASYYTPVGGLPELRQAVATHIKTDTGYDAKMEQVAVTVGAKMGL
                     FETFQALLNEGDEVMIVAPFWVSYEEQVKLAGGSVIAIHPQASDLKTTPSELSRFKTAS
                     TKLLILNTPQNPSGLVYSEEETRAIAQWAVDNNVILVADEIYGKLVYNGAKFSSVMSMG
                     NEIVNNTILIDGVSKAYAMTGWRIGYVVAAPQIIRKILALQGHMTSNPTAVAQYAALEA
                     LRGDQYPVEEMRLAFEKRLNQTFDLMQVIPGFSFDYKPEGAFYLFPDVTEAMKIKGYAT
                     STDLAMALLKEAHVAVVAGEAFGMPGHIRLSYATSQTLLSEAVRRIQNFMN"
     CDS             complement(8139..8864)
                     /locus_tag="ctg1_241"
                     /transl_table=11
                     /translation="MPVGIIINALSVLLGGIFGAIGGRKMSNNFKDGLNMAFGICSMTM
                     GIYAIAPMKNMAAVIFAVIIGTGIGLLIHLGDLINRGAAKMQQLISRFVSSPTGLDQKT
                     FDATLVTVIVLFCASGTGIYGALTEGMNGDATILISKSILDFFTAAIFAANLGYVVSLI
                     AIPQFIIFIILFLMAHSIYPLTNPAMIFDFKAAGGVLMLATGFRMVQLKMFPTADMIPA
                     MVIIMPISWLWMTVILPML"
     CDS             9004..9888
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_242"
                     /sec_met_domain="LysR_substrate (E-value: 1.3e-25,
                     bitscore: 86.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.9e-15, bitscore: 51.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKKLVTFVDLAQTKNYSKTAERIFTTQATVSKHIMALEKEWNV
                     ELFSRAHREINLTDVGKLLLPQVKELLRVEQKIHQTINLQQTQKEQSLVIKGVPSISQY
                     QAFDIITNFAKQNPEIKLKFSESETELLIDSLEQDEADIIFTRTFDKANSKYETIVSEH
                     DYFVLLVPKENPLAKIQQVEIKMLQNESLLLLGDSTKLYTPVISMLKEEGIKPHILYEG
                     RRINLILEMLNQGMGVSIMMNKSFDLTDYPEVVAIPIIPKKTSELIFLKKKSNMTNAVN
                     SFWKFAIAETRLE"
     CDS             10001..11476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_243"
                     /sec_met_domain="gallic_acid (E-value: 4.7e-224, bitscore:
                     740.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQPYDLRKVLEEMKKLPGQYHETDVEIDPDADLAGVYRYIGAG
                     GTVKRPTAEGPTMMFNNVKGFPDSRVLIGLQASRKRVGKILHHDYKTLGQMLNDAVSNP
                     IAPTEVTRAEAPAQEVVHLASDPDFDIRKLLAAPTNTQDDAGPYITMGVVYGHSMDKKQ
                     SDVTIHRMVLEDKDTIGMYIMPGGRHIGAFLKEYEEQNKPMPITINIGLDPAITIGATF
                     EPPTTPLGYNELQVAGALRNEPVQVVPGVEVDALGIARSEWIIEAEIMPNQSMQEDINT
                     NSGYAMPEFPGYNGTANPAVNVIKIKAVTHRKDKPIVQTTIGPSEEHVSMAGIPTEASI
                     LSLVGRAIPGKVLNVYNAPAGGGKLMTIMQIHKENEADEGIQRQAALLAFSAFKELKTV
                     ILVDDDVDIFDWNDVMWTINTRFQADRDIMVLEGMRNHPLDPSELPDYDPARIRVRGMS
                     SKLVLDGTVPYDMRDKFKRAAFKEIADWKKYLD"
     CDS             11498..12094
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_244"
                     /sec_met_domain="Flavoprotein (E-value: 3.2e-26, bitscore:
                     88.7, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVVGISGASGTIYGIRLLEVLHRMPDVETHLVMSRWAKENLA
                     IEDTGYTESQLKDLADFVYSEKNMGATVASGSFIHDGMVIIPASMKTIASVATGLGENL
                     IARAADVTLKEQRQLIVVPRESPFNQIHLENMLKLSKMGVGVIPPIPAFYNNPKTIDDI
                     VNHTVMKILDHLHIQNDVSSRWEGLANARKNNQKK"
     CDS             12066..12509
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MPEKIIKKSSQNKNSFEVNVTQADYTMTAMLERQSLDLLIQIIGG
                     DVAHYGVVMTIDKTGHEETIALPSRPGHVHQENVLIDQVAKAIKPLLQGNAFFVSGMHV
                     NDITPEQMHAAIPMAQTLGEELAKWLEKHPGSKPIVSYAKSNK"
     CDS             12664..13599
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_246"
                     /sec_met_domain="ADH_N (E-value: 1.1e-11, bitscore: 41.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-16, bitscore:
                     57.1, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIAISAYGDVDQLHEEELDIPQIANDEVLVKIKATSINPIDWK
                     ARMGFLKQMYDWQFPVVLGWDLSGIITQVGKDVKHFKVGDEVFARPDIYEDGTKGTYAE
                     YAAVKEDKLALKPSNVSFEAAAAIPLAGLTAWQVIVDRLKIKKGDKVLIQAGAGGVGIF
                     AIQIAKHLGAYVATTASAKNAEFLTNLGADEVIDYHEHQIGEVLNQYDAVFDTVDDLEA
                     GLAILKPTGKLVTIAGRPTQAQQDAQPSATSWWLQPNGKQLAELGDLVAEGEVKVIIDS
                     TFPLTEDGLRAAHERSQTNHARGKIVINVE"
     CDS             13726..14664
                     /locus_tag="ctg1_247"
                     /transl_table=11
                     /translation="MGLLMLGLVAGAVVPFQTAVNSRLRTYVISPFVSSLISFMVGTIF
                     LIVIIVLSGGQLLLTNAQLHAIPWWMYLGGVLGMIGLTTNILLFPILGSVQTVIMPVLG
                     QIMMSMIIDNYGMFGTTRHPLSLMRMVGVLLLIVGVLIVVALPEYLARNSMKRPPEQRV
                     KWKWLWQIFGVLVGGMLAIQAALNGRLGGLLQAPIHAALISFFIGTIMLFLVAVFQGTL
                     KNIRLVVQQKTPWWVWIGGFFGAAYIFLNAYLVPQIGTGTVVVLVLLGQIISSLNIDQF
                     GLLGSMKSSISVAKIAGLIIMIAGVGLIEVM"
     CDS             complement(14681..16984)
                     /locus_tag="ctg1_248"
                     /transl_table=11
                     /translation="LDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQ
                     NAKVNLIEADDRIETHAEIQQQKGLVARAVENEAILKRQIDELSDLQKSPYFGRIDIKD
                     ADEPDIESLYIGISSFADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETELIK
                     KRQFTINHGEIQHMFDTNETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSD
                     LLVVQGVAGSGKTSAILQRIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGER
                     NMRQLTLAEFFSRRLEGMQVQTLFDRFENQHQLTEYEQNLIDFKESQDFIELIQAYEKQ
                     LSTKEIKFTNINYRGEIFFSKEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQE
                     IKQDWVQNQIDQISDEKYHGLVGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFI
                     DSYSQYADFLSQIDLGDFDWQKVAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRK
                     FQYVFVDEMQDYSVAQLMYLKHAFPRAKFTLLGDSEQTLFKDVTEPQILLAKLKQAFHV
                     KRANLITLNRSYRSTAQITNFAAALLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTN
                     LCRDELQQYGTIAILTKNMAESEHVATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGL
                     EFDSVIAYNVSEANFPGRLWRGTLYTIASRAMHQLHLISIGKVSNLITQIKPDQFSFQK
                     SFNITPHKSQKLDE"
     CDS             17321..18349
                     /locus_tag="ctg1_249"
                     /transl_table=11
                     /translation="MTSKKIILTGDRPTGKLHIGHYVGSLKNRVQLQNTGDYETFIMIA
                     DMQALTDNARDPEKIRNSLIQVALDYLAVGIDPAKSTIFVQSQIPALSELTQHYMNLVS
                     VARLERNPTVKTEIKQKAFGQSIPAGFFTYPVSQAADITAFKADTVPVGDDQEPMLEQT
                     REIVRSFNNIYQKEVLVEPEGYFPPKGMGRIPGLDGNAKMSKSLGNAIYLADDEETIQK
                     KVMSMYTDPQHIRVEDPGHIEGNTVFTYLDIFDPDKQKVQELKDQYQAGGLGDVKIKRY
                     LNEVLQNELRPIRERRERYEADIDAVYQILKDGSDKANAVAEQTLKEVRDAIGINYFDH
                     RL"
     CDS             18508..19437
                     /locus_tag="ctg1_250"
                     /transl_table=11
                     /translation="MKNLVIVDLGSNSARMAINSIADDGTFREIKRVKEDSRISEGMGR
                     ERLLRPQAMNRTIAALRRFKEIYEEYPNTEVRGITTAAVRMARNQNDFLNRVKQETGIK
                     LHVLSGDDEAYYDYLGVINSLEVKDCLILDTGGASCELIDVHNGKARNMISIPIGAVSL
                     SERFRLTDVVRADNLFAAEIFVNKQLRDVWWIMDAFNKPIVLLGGANRTLARMNRRHQK
                     ISRINNIHGYRLKTESVNRTFKSLITRNLEARKKMSGLETTRADIIVGGMLPLVMLLQM
                     IDADRVIFSESGVREGIISEYINFRKEE"
     CDS             19443..20675
                     /locus_tag="ctg1_251"
                     /transl_table=11
                     /translation="MIEGYHKLTRQQQLEQLAQETDVDLSELTELAMDSIHQQQIENYL
                     TDFNLPEGIAVNLVVNGQAYVVPMVTEEPSVIAAASYGAKMVQRAGGFSANSRRIMLGQ
                     LLISSAQPAPIIDYVKKQKSHLLKVANAAHPSMQARGGGAKNLRIRQLTATKLSVDLMV
                     DTREAMGANTINSMVEAVKKDLVTQQIDVDMAILSNLADQALTEVTCQIPVNQLGVEVA
                     KKISLASDYAQIDPYRAATHNKGIMNGIDAVVMASGNDWRAIESGAHAYAAQNGQYQGL
                     STWDVVGDQLVGRMELPLPVATVGGSIGINTQAQLNLKLMQIKNAKQLAEVIAAIGLAQ
                     NLAALRAIVSEGIQSGHMRLQAKSLLIEHGATQAELGDAVNRLVQAERIDAKNAQQIIK
                     QLRKKDNDEQS"
     CDS             20662..21618
                     /locus_tag="ctg1_252"
                     /transl_table=11
                     /translation="MSKVEVNDTVKSLLEEVNASFPGEVRIGFGEEQAGFVRHDQAQQF
                     VEEGKMLIKVNDITAPNYTASHELIHMLMILKGFPQLYFQLSTGEKDTDNQLMFLITEL
                     YDVIAHEVVVKEQRRHYLIDDEVEEAFFKGIEDAVEAEDAGKVDGFSTIRLIMMMDAIT
                     FYGNGLANFETRLMDAFPTTYQAAKKIMQELDQRTISNPFDFRRKVVKAFELIDTQLKE
                     WDLPEIHAMEFATLGSVFSERQLRLSVKQLFQIFHSDLHEKAQDTRGFVGLGISDQQNA
                     FVVPTPKDMPSDEYFRELYAKNVKDFFEEMKMPYTIR"
     CDS             complement(21668..22075)
                     /locus_tag="ctg1_253"
                     /transl_table=11
                     /translation="LKKLFTNTIFIQSNLERLSTILKSPQNLSKWVPDINSVSPKDDYF
                     LISRSSSALNNFEKISVTSQDNSIIYTSTGGRLEYELHFDLTNKDDRTLVEQTLLVDET
                     LTKLPLTLLAPIAKHAFHENLSSLERLIAIS"
ORIGIN
        1 aatggtaaga agattaaaga ttacaatctc cgagagctgc gtctgaatgt aggatatgtt
       61 ctacaacaaa ttgcattgtt tcccacgatg accgttgaac aaaatattgc gttaattcct
      121 gaaatgaaac actttaaaaa agaggatata aaaagacggg tagatcaact ccttggtgat
      181 gttgatcttg atcctgaaaa gtatcgaaat cgccacccca gtgatctttc gggtggtgaa
      241 cagcaacgca ttgggatttt acgggcgatt gcttcagaac caccagtcgt cctgtttgat
      301 gaacctttta gtgcgttaga tccattagtg cgaaatcaat tacaagattt ggttttgaag
      361 ttacatcaaa agttgaagaa tacgattata tttgttaccc atgatatgga tgaagcttta
      421 aaactaggag atcgaattgg ggttatgaac gatggtaaat tattgcaagt cgccacccca
      481 aaggaaattg cacagaatcc ggaaaatgct tttgtggaga atttcttctc tgctacggtg
      541 ggtaaaaatc tatataagac acctattgaa aaaattattc gaacgggctt tgaaattcca
      601 gaaccgcatg aggcagaacc aatatctgaa attaatgcta aagatacttt agaaaaagct
      661 tttgcagcaa tggctgaagt agaaatatta aaagtagtag atgaagataa atcaacggtt
      721 aattgggttg accgagcatc attatttagg tatttaagtg aaaccaaaca ttaagggagg
      781 taaattaaat gaaaaagtat gacgttgtga ttattggagc aggacctggt ggattaggat
      841 tagcttatcc tttaaaagaa gcggggttgg aagtggcagt tgttgaagaa aatctttggg
      901 gcggaacgtg tcctaatcga ggatgtgacc ctaaaaaggt tctattagca gcgattgaag
      961 ctaaaaaaca aaatcaatat ttgcttggta atggaattaa aaatgagact caaattgatt
     1021 ggcctgcttt aatgcaattt gaaaaaacat ttacagatcc agtttctaga agcagccgtt
     1081 caggtttaac ggacgctcaa atcgatgttt atgatggaca tgctgaattt attgaccacc
     1141 acaccttgaa gatcgatcaa acaaccatca ccagtgaaaa atttgtgatt gcaacgggac
     1201 aacgccctag tcgattaaca aatattgaaa atcaagagat gatgcagact agtacagatt
     1261 tcttaaagat ggatcatcta ccaaatgaac tggccttggt cggtggagga tatatagcat
     1321 ttgaattggc gatgattgct agtggcgcag gggctaaggt acacattatt catcataatc
     1381 aacgcccatt aaaagctttt cctaaagcat atgtcgatga cttagtcgat caacttaaaa
     1441 ctcaaggagt tgaagttcac ttaggaattg atttaaagcg ggtagaacct aaggatgaac
     1501 ggtttgagtt gagtgatgga caaggtttca agcaaatcgt tgatcaggtt tttgttacag
     1561 ctgggagaaa acccaatgat gatagtttaa atctagaaaa gattggtgta caaactgatc
     1621 gtggtggaat cgtagttaat gaatatttgg aaacatcggt tgataatatc tatgcgatgg
     1681 gggacgttgt ttccaaggcg cttcctaaac tgactccagt atctggattt gaagcccgtt
     1741 atttggctaa aaagctaacg aatgcaaccc aagcagcgat tgattatcca gcaatcccta
     1801 ccgtagtata cggaatgcct aaattggcta aggtaggagt tgaattggat gaggcgcagc
     1861 aacatccaga acaatatgaa ataaagacag cggagatgac agagtggttt acttatcggc
     1921 gtttacaaga tccgttcgct aaaattagtg ttattcatga aaagtccagt ggaaaaattg
     1981 ttggtgcaat tacaatgagt agtgaagcag aacatctaat taatgattta acgatgatta
     2041 ttaatcaagg gggattagta gatcaaatca acaatcaaat cttagcttat cctacggaag
     2101 ccagtgattt aggctatatg tagtatactt aattagtgat tgttataatt tagctttatt
     2161 ttgaaaggaa cgtggtttaa tggagttcgt gggcgtactt gtactaattt tagtactgac
     2221 ccttttagct ggtcattttg ctcaacgaat gggatttcct gcagttgtag gacaattatt
     2281 ggtcggaatt attttagggc ctggaatttt agggattatt cattcagacg aattgatatc
     2341 agtgttttca gaaatcgggg taattatcct gatgtttcta gcaggactag aaagtgatct
     2401 gaaaatgttg aaaaaataca tcaagccggc gctggtagtt gcgatattag gggtagtttt
     2461 acccattgta ttagtcggtg gcgcgagcct tctttttgga gtccatccga tggaagcact
     2521 attcatcggg gtcatctttt cagctacttc agttagtatt tctgtggaag tcttaaagga
     2581 atatcacacc ctaaatacta aagagggggc caccattttg ggggcggctg tagccgatga
     2641 tattattgga gttttattac taggtgttat gattgcgttg actagttcta aatcgggatc
     2701 caattcaaac gtggggatgg ccatctttta tcaagtgtta ttcttcattg gagtatatgt
     2761 gatcggaaaa tgggtggttc cgatgcttat gcgcctttca gaccaactgt ttattacggc
     2821 ttcgcgccca gtgatgtcga ttattatttg tttaggttta gcgtggctgg ctgatgtagc
     2881 cggtttgagc ggagcgatcg gcgcattttt tgcgggagta gccgtttcgt taaccgatga
     2941 agatgatgaa atcaatgaga gcattgaacc aattggttat gctatcttta ttccagtttt
     3001 cttcgttagt gttggtttat caatgaattt tgatggactt caaactgtac tgggactaat
     3061 tgtggtatta actattttag ccactattac caaattattt ggttgtggat taggagctcg
     3121 aatgtcggga tttgatttaa ctagtagtgg ggtaattgga gctggaatga tttcccgtgg
     3181 cgagatggcg ctaattactt tacaaattgg ttatggtgaa catttaatga gtgaaactta
     3241 ttattcagca attgtattag tgattgtttt ggttaccctc attgcaccgt ttattttgaa
     3301 ggatgctatt aagaaaaata aagcagctac tcatgcttaa aaactaaact tagaattttc
     3361 atcaaattct aagtttagtt tttttattta gcaaattaca caacaagacc cgtttaattt
     3421 gatacaatga acattaaata ttgattaaat cacgaacaat ttaattaggg aggtccacta
     3481 tgcaccgtat tttaattgcc aaccgaggcg aaattgcgac ccgaattatt cgggcaacgc
     3541 atgaactcgg aaaaacagct gtagcaattt atgctaaagc ggatgaattt tctatgcatc
     3601 gttttaaagc agatgaagct taccaagttg gtgaagatag tgatccaatt ggagcatatt
     3661 taaatattga tgacattatt cgtattgcaa aagaaaataa tattgatgca attcaccccg
     3721 gctatggatt tttgtcggaa aatgctgtat ttgcgcgagc agttgaagca gctgggatta
     3781 agttcattgg acctcgaccc gaattactag aaatgtttgg tgataaatta caagctaaaa
     3841 atgcagccat taaggccggt gtaccaacta ttccgggaac ggaaaaacca gttaaagatg
     3901 tcgatgacgc gctaaatttt gcagagcaat ttggctatcc tatatttgtt aagtcagcgg
     3961 caggtggcgg tggaaaaggg atgcggattg tacatcatca acaagaaatg cgcgaagcat
     4021 ttaagatggc tcagtcagaa gcttcttcgt cttttggtga cgatgagatt tacctagaac
     4081 gttacttagt tgatccgatc catattgagg ttcaagtagt cgcggatgaa cacggtgaga
     4141 tggttcattt gtatgaacga aattcatcga ttcagcgacg ccatcaaaaa atcattgaat
     4201 ttgctccagc ggtgggaatt tctgccaccg tccgtgatca aataagaaaa gctgctttaa
     4261 aattattgaa gtcggtcgat tatagtaacg ctgcaaccat tgagtttttg gtagaaggta
     4321 atcaatttta ctttatggaa gtgaacccac gaattcaggt tgaacataca gttaccgaag
     4381 aagtcacggg aattgatatt gtgcaaaccc aaattaaggt tgcagaaggc caaagattgc
     4441 acgaagaaat cggtgttcct caacaagccc aaattgaagc tgtgggagtg gcaattcaag
     4501 ctcgaattac cactgaagat ccaatgaata actttattcc agatgtcggt agaatccaga
     4561 cgtatcgttc acctggtgga acaggtgtga gattggatgc tggaaatgcc tttgctggcg
     4621 ccattgtaac tccgcattat gattcacttc tgaccaaggc gattgtccat gcgccaacct
     4681 ttgacgaagc cttggtaaag atggatcggg tgctcaatga atttgtaatt gctggggtta
     4741 aaactaatat cccattttta aagaaattaa ttcatcatcc tatttttaga tcggaattag
     4801 ctccgacaaa ctttgtggat gagacaccag aactctttga tttaaaagct gaaaccccgg
     4861 tagttactca acttttgagt tacattgcta atactaccat caatggttat ccaggcttag
     4921 aaaagcagaa tccagtagtg ttaactcggc cagtccgtcc acattttgaa gcacaagtac
     4981 cgcatgaaaa tgcgaaacag atcttggata gtaagggacc tgatgccatg atcaattggc
     5041 tgttaaaaca aaagcaggtc ttgctaaccg atacgaccat gcgggatgcc caccaatcat
     5101 tatttgctac gcgaatgcgg accaaagaca tggtagaaat tgccgatcaa gtccagaaag
     5161 gtctgcctaa cctattttca gctgaagttt ggggcggtgc gacctttgat gttgcttatc
     5221 ggttcctagg tgaggatcca tgggtaagac tccaacaatt gcgggctaaa atgccaaata
     5281 cgatgctcca aatgctttta cgtgggtcaa atgcagtagg gtatcaaaat tatccagaca
     5341 acgccattga cgaatttatt cgattggctg ccaaaaatgg aattgatgtt ttccgaatct
     5401 ttgattccct taattgggtt ccacagcttg aagaatctat ccaacgggtg cgtgataatg
     5461 gaaaagtggc tgaagcagcc atggcatata ctggcgatat tttagatact aatcgtacta
     5521 aatataattt gaaatattat gtggatttgg ctcaagaact ccaagcagca ggtgctcata
     5581 ttattggaat caaagatatg tcaggaattt taaaaccaca agctgcttat gcattaattt
     5641 cagagttaaa aaatcatctg gatgtgccaa ttcatttgca tacgcacgat actacaggca
     5701 acggcatttt cttatattct gaagcaatac gagctggagt tgatgtggtc gacgttgcca
     5761 cttctgcgct agcgggaacg acttctcagc cttcaatgca gtctctttac tatgcgttgt
     5821 ctaataacca gcgtcaacca gatttagaca ttcaaaaagc ggaaaaacta gatgaatatt
     5881 gggctggaat tcgaccatat tacgaaggat ttggcaccca attaaatgga ccacaaactg
     5941 aaatttatcg aattgaaatg cctggtggac agtataccaa cctgcgccag caagctaatg
     6001 cagttcattt gggtaagcgt tgggatgaga ttaaggaaat gtacgcgacc gtcaatcaaa
     6061 tgtttggcga tattccaaag gttacgcctt cttctaaagt agttggcgat atggcactat
     6121 tcatggtcca aaatgatttg acgcctgaaa tggtaatgaa cgataaggga caattaagtt
     6181 ttcccgaatc agtggtaaac tttttccgtg gtgatttagg acaaccggcg ggtggttttc
     6241 caaaacagct ccaaaagatg attctaaaag agcaagcccc attgacagta cgaccaggag
     6301 ctttagccga tccagttgat tttgatcaag ttcgtaaaca ggcaactaag gttttaggtc
     6361 accaagcaag tgatgaagaa gttatgtcgt ttattatgta tccagatgtg atgaccgaat
     6421 acgttcaacg tcaaaatgaa tatggtccag taccattatt agatactcca atctttttcc
     6481 aaggcatgca tattggtcaa cgcattgatt tacaattggg acgcggaaaa tcggtcatta
     6541 ttgtccttcg agaaattagt gaagcagatg aggcgggcca aaggtcactt ttctttgata
     6601 taaatggaca aagtgaagaa gtgattgttt atgatgttaa tgcgcaggta acgaaagcaa
     6661 agaagattaa agctgatcct actaaagccg aacagattgg agctactatg gcgggttcgg
     6721 tcattgaagt tcaagtagaa gcgggccaaa aggtccagca aggtgataac ttaattgtca
     6781 ctgaggcgat gaaaatggag accgcgttaa gagcaccttt cgacgcgacc attaagaaga
     6841 tttatgctac ccctgaaatg caaatcgaga cgggagattt attgattgaa ctagaaaagg
     6901 agtaatctga tggaattttc gaagcgggct aatcaagtta gtccatcagc aacattagca
     6961 gtttcaactg aggcaaaaaa aatgcaggcg gccggcatcg acgttgttaa tttgagtacg
     7021 ggagaaccgg attttgctac tcctaaggcg attattaaag cggcgatgga aagcatggaa
     7081 tctggtaaag caagttatta cacaccagtc ggagggctcc cagaacttcg ccaagcagtt
     7141 gctacgcaca ttaaaaccga tacaggttat gatgccaaaa tggaacaagt ggcagtaacg
     7201 gtaggggcta aaatggggct gttcgaaact ttccaagctt tattgaatga aggcgatgaa
     7261 gtcatgatcg ttgccccatt ctgggttagt tatgaggaac aggtgaaatt agccgggggt
     7321 tcggtgattg ccatccatcc tcaagctagt gacttgaaaa ctactccttc agaattaagt
     7381 cgttttaaaa cagccagcac aaaattgtta attttaaata cgcctcaaaa tccctcggga
     7441 ttggtatatt cagaagaaga aacacgggcg attgcacaat gggcggtcga taacaacgta
     7501 atattagttg cagatgagat ttacggtaaa ttagtttaca atggggcaaa attcagttca
     7561 gttatgagta tggggaatga aattgttaat aataccattt taatcgatgg ggtttcaaaa
     7621 gcgtatgcaa tgactggatg gcgaattgga tatgttgtag ctgctccgca aattattcga
     7681 aaaatattgg ctttacaagg tcatatgaca tcaaatccga cagcggtagc gcagtatgcc
     7741 gctctggaag ctttgcgtgg agaccaatat ccagtggaag aaatgcgatt ggcatttgaa
     7801 aaaaggttga accaaacttt tgatttaatg caagtaatcc ctggttttag ttttgattat
     7861 aagccggaag gggctttcta tttatttccg gatgttactg aagctatgaa aattaaagga
     7921 tatgccacat ctacggactt ggcgatggct ttactaaagg aagcgcatgt agccgttgtc
     7981 gccggtgaag cgtttggaat gccgggacat attcgacttt cgtatgcgac gagccaaaca
     8041 ttattgagtg aagcagttcg tcggatccaa aattttatga attaattaga gctatataaa
     8101 aagcagatac ctaaccggta cctgcttttt atatggtttt ataacatagg taagataacg
     8161 gtcatccata gccacgaaat gggcataatg atgaccattg ctggaatcat gtcagcagtt
     8221 gggaacatct tcaactgtac cattctaaaa ccagttgcta gcattaaaac tccgcccgca
     8281 gctttgaagt caaaaatcat agctggatta gttaatggat aaatcgaatg agccataaga
     8341 aataagatga taaaaattat aaattgtgga attgcaatta gggaaacaac gtatccaagg
     8401 ttagctgcaa aaattgctgc cgtgaaaaaa tcaaggattg atttcgagat taaaatggtt
     8461 gcatctccat tcataccttc agttaaggcg ccataaatcc ctgtaccact ggcacagaac
     8521 aaaacaatta ctgtaacaag cgtggcatca aaagtttttt gatctagacc agtggggcta
     8581 gatacaaagc gggaaatcaa ttgttgcatt tttgcagctc cgcgattaat taaatctcct
     8641 aaatgaatta agagaccaat tccggtacca atgataacag caaatatgac tgctgccatg
     8701 tttttcatgg gagcaattgc atatattccc atggtcattg aacagattcc aaatgccatg
     8761 tttaatccat ctttaaagtt gtttgacatt tttcgaccgc caattgctcc gaaaattcct
     8821 cctaataaaa ctgaaagagc attaattata attccaactg gcataataaa agcctcctgt
     8881 gcttaattca tttatatagt ttgttaaact cacaagaaag tagtttacag ttttgaaaag
     8941 cacggaacaa ttcaagtttt atggtaaaat attccaaact agaataagtt agaaggaaca
     9001 aagatggata caaagaaact agttacattt gtagatttag ctcaaacgaa aaactacagt
     9061 aaaactgcgg aacgcatttt tacaacccag gcaacagttt caaaacatat tatggctctt
     9121 gaaaaagagt ggaatgtcga attgttttct agggctcatc gagaaataaa tttaacggat
     9181 gtaggaaagc ttttgttacc tcaagtgaag gaattattga gagtagaaca aaagatacat
     9241 caaacgatta atttgcaaca aacccagaag gaacagtcac tggtaatcaa aggagttcct
     9301 tcaatttctc agtatcaagc ctttgatata attaccaatt ttgcaaaaca aaatccggaa
     9361 ataaaattga agtttagtga atcagaaaca gaacttttaa ttgatagttt ggaacaagac
     9421 gaagcggata ttatttttac tagaactttc gacaaagcta attctaaata tgaaactatc
     9481 gttagtgaac atgattattt tgtactacta gttcccaaag agaatccact agcaaaaatc
     9541 cagcaagttg aaattaaaat gcttcaaaat gagtctttat tattattagg tgattcgaca
     9601 aagttgtata ctccagtcat ttcaatgtta aaagaagaag gtatcaaacc ccatattctt
     9661 tacgaaggta ggagaattaa tctaattcta gaaatgctaa atcaaggaat gggagtatca
     9721 attatgatga ataaatcttt tgatttaact gattatccag aagttgttgc aatcccaatt
     9781 attcctaaaa agactagcga gttaatcttt ttgaaaaaga aaagtaatat gaccaatgca
     9841 gtaaattctt tttggaagtt tgcgatagca gaaactcgat tagaataaac taaaacccca
     9901 tatattccat aatggaatgt atggggtttt agtttgaatt gtttcgtcgt caaatttaaa
     9961 tgataatgac cttgtaaaat aatttaagga ggttcgtaag atgaccgaac aaccatatga
    10021 tttaagaaaa gtactcgaag aaatgaaaaa attacctgga caatatcacg aaaccgatgt
    10081 tgaaattgat ccagatgccg atttagctgg tgtatatcgt tatattggag caggcggtac
    10141 agtaaaacgt ccaacagctg aaggaccaac gatgatgttt aataacgtca aaggatttcc
    10201 agatagccgg gttttgattg gacttcaggc ttcgagaaaa cgagtgggaa aaattctaca
    10261 ccatgattat aaaactttag ggcagatgtt aaatgatgca gtttcgaatc caattgctcc
    10321 gacggaagtt acaagagcag aagctcctgc gcaagaagtt gttcatttgg catccgatcc
    10381 cgacttcgat attcgcaagt tattagcagc gccaactaat acacaagatg atgcaggtcc
    10441 atatattaca atgggtgttg tttacggtca tagtatggat aaaaaacaaa gcgatgttac
    10501 catccatcga atggttttag aagacaagga taccattggt atgtacatta tgcctggtgg
    10561 acgccatatt ggggcctttt tgaaagaata cgaagaacaa aataaaccta tgcctatcac
    10621 tattaatatt ggattggatc cggctattac aattggagct acctttgagc cacctacaac
    10681 tccattaggt tataacgaac ttcaagtagc aggagcccta agaaatgaac cagttcaagt
    10741 agtgccaggt gtagaagtcg atgctttagg aatcgctcgt tcagaatgga ttatcgaagc
    10801 tgaaattatg ccaaatcaat caatgcaaga agacattaac acaaattcag ggtatgccat
    10861 gcctgaattt cctggttata atgggactgc taatccggct gttaatgtta taaaaattaa
    10921 agcagtaact catcgtaagg acaaacctat cgttcaaaca actattggac cttcagaaga
    10981 gcacgtttca atggcaggta ttccaacaga agcctctatt ttaagtttag ttggtcgtgc
    11041 tattccagga aaagttttga atgtgtataa tgcgcctgct ggtggtggaa aattaatgac
    11101 gattatgcaa attcataaag aaaacgaagc ggatgaaggt atccaacgcc aagcagcttt
    11161 actagcgttt tctgccttta aagaattaaa gacggttatt ttagtggacg atgatgtcga
    11221 tatttttgat tggaacgatg ttatgtggac cattaatact cgtttccagg ctgatcgaga
    11281 tatcatggta ctggaaggaa tgcgtaacca tccgttagat ccatcagaac taccggatta
    11341 tgatccagcc cgaattcgag ttcgaggaat gagttctaaa ttagtgcttg atggtacagt
    11401 accttatgat atgcgagata aatttaaacg tgcggctttt aaagaaattg cagattggaa
    11461 aaaatattta gattaatgtg gtaagtggag ggaataaatg aagaagattg ttgttggaat
    11521 ttcaggagca agcggaacta tttacggaat tcgattatta gaagtgttgc atcgtatgcc
    11581 agatgtagaa acccatcttg ttatgagtcg ctgggcaaaa gaaaatttag ccattgaaga
    11641 tacaggttat acggaatctc aacttaaaga tttagcagat tttgtatatt ctgagaaaaa
    11701 tatgggtgcc acagttgcca gtgggagttt tatccatgat ggaatggtaa ttattccagc
    11761 cagcatgaaa acaattgctt cggttgcaac agggctaggt gaaaatttaa ttgctagagc
    11821 tgctgatgtg accctgaaag aacagcgaca gctgattgtc gttcctcggg aatcaccatt
    11881 caatcagatt catttagaaa atatgttaaa gctttctaaa atgggggtag gagttattcc
    11941 gcccattcct gcgttttata ataatcctaa aacgattgat gatatcgtta accatacggt
    12001 tatgaaaatc ctagatcatt tgcatattca aaatgatgtt agttcgagat gggagggatt
    12061 agctaatgcc cgaaaaaata atcaaaaaaa gtagtcagaa taagaattcg ttcgaagtta
    12121 acgtaactca ggctgattat actatgacgg ctatgcttga acgccaaagt ttagacttat
    12181 tgattcaaat cattggcgga gacgttgcac attatggtgt tgtaatgaca attgataaaa
    12241 ccggacacga agaaaccatt gcactaccaa gccgcccggg acatgttcat caagaaaatg
    12301 ttttgattga ccaagttgct aaagcaatca aaccattgtt gcaaggtaat gctttttttg
    12361 tatcaggaat gcatgtgaac gatataactc cagaacaaat gcatgctgct attcctatgg
    12421 cccaaacttt aggggaagaa ttagctaagt ggcttgaaaa acatcctggt agtaagccaa
    12481 ttgtgagcta tgctaagagc aataaataat taaaatagaa tcctcagcat tgtttgtttt
    12541 gcaatgttga ggatttttta taagatttgg caataaatga gacttaaatg tagaacttac
    12601 tttttataag tgatatgctt aaaaaatata tattgaattt atctaagtct agggggaaca
    12661 aaaatgaaag caattgcgat tagcgcatat ggtgatgttg accaacttca tgaagaggag
    12721 ttagatattc ctcaaattgc aaacgatgag gtcttggtaa aaattaaagc aactagtatc
    12781 aatccgattg actggaaggc tcgaatggga tttttgaagc aaatgtacga ttggcaattc
    12841 ccagttgttt taggatggga tctttccgga ataattaccc aagtcggtaa agatgttaag
    12901 cattttaaag ttggagatga agtctttgct agacccgata tttatgaaga tgggacgaaa
    12961 gggacatatg cagaatacgc ggcagttaag gaagataaat tagcattaaa gcctagcaat
    13021 gtttcgtttg aagcagcagc tgcaattcca ttagctggac tgactgcatg gcaggtgatt
    13081 gtagatcggt taaagattaa aaagggtgat aaagttttaa ttcaagcagg agctggcgga
    13141 gtcgggattt tcgccattca aattgctaaa catttaggag cctatgtagc cacaacggct
    13201 agcgccaaaa atgcagaatt tttaactaat ttaggggcag atgaagtcat tgactaccac
    13261 gaacaccaaa ttggggaagt ccttaatcag tatgatgctg tttttgatac agttgatgat
    13321 ttagaagcgg gactagcaat tttgaaacca accgggaaat tggtcaccat cgcgggacgc
    13381 ccaacccaag cccaacagga cgctcaacct tcagcaactt cttggtggct ccaaccaaat
    13441 ggcaaacaac tggctgaact aggtgattta gtggctgagg gcgaggtcaa agtaattatt
    13501 gatagtacat ttccacttac tgaagatggg ttacgagcgg ctcacgaacg cagtcaaact
    13561 aaccatgcta gaggaaaaat tgttatcaat gtggaataga aaatgaaaat gtaaaaagtc
    13621 atgacattgt tgcttgtgtc atgatttttt tagtttaaaa taaagttata gtaacgatgg
    13681 aaacgcttta accgaaacta ggatagcgtt gaaaggaagc acataatggg actattgatg
    13741 ttaggattgg ttgcgggtgc ggtagtaccc tttcaaacgg cggttaattc acgattaaga
    13801 acgtatgtta tttcaccatt cgtatcgtct ttgatttctt ttatggtggg aaccatcttt
    13861 ttgatagtaa tcattgtttt aagcggtgga cagctcttat taactaatgc gcaattacat
    13921 gccattccat ggtggatgta tctcggtggt gttttgggga tgattggatt aacaactaat
    13981 attcttttat tccccatttt aggtagtgtt caaacggtga tcatgcccgt tttaggtcaa
    14041 attatgatga gtatgataat tgataactat ggcatgtttg gcaccacacg ccatccactt
    14101 tcgttaatgc gaatggtcgg agttctacta ttgattgtgg gggtattaat tgtggtcgcc
    14161 ttaccagaat atttagcacg gaattctatg aaaagacccc ctgaacaacg agttaagtgg
    14221 aaatggttat ggcaaatttt cggcgtgctt gtgggcggaa tgctcgcaat tcaagcagca
    14281 ttaaatggac gattaggtgg gttattacag gcccctattc acgctgcttt aatatcattt
    14341 tttattggaa caataatgtt attcctggta gctgtattcc aaggaacttt aaaaaatatc
    14401 cggctagttg ttcaacagaa aacaccttgg tgggtttgga ttggcggttt ttttggagca
    14461 gcttatatct ttttaaatgc atatttggta ccacagattg gaactggaac ggtagtagtg
    14521 ctagttttac tgggacaaat tatcagtagt ttaaatattg atcagtttgg cttattagga
    14581 tcgatgaaat cgagcatctc agttgctaag attgcgggct taatcattat gattgctgga
    14641 gtaggattaa ttgaagtaat gtaaacaaaa aactcgacgg ttattcgtcg agtttttgtg
    14701 atttatgagg agtgatgtta aatgattttt gaaaactaaa ttgatcaggc ttaatttggg
    14761 taattaaatt ggatacttta ccaatactaa ttaagtgtag ttgatgcatg gctctggaag
    14821 ctatcgtata taaagttcct cgccacaaac gaccaggaaa attagcttcg gaaacattat
    14881 aggcaattac ggaatcaaac tctaatcctt tagctaaata aatgggtaaa acgacaatac
    14941 ctttgggtaa ggaacggtcg ccatcgttta ataagctcgg ttttaattcg tgaagcaagg
    15001 ttgctacgtg ctcactttca gccatgttct tagttaaaat agcgatggta ccatactgct
    15061 gtaattcatc ccggcaaaga ttggtcatat cgactacggc ttgttgttca ttatcagcaa
    15121 tgattacttt aggtaaatct ccttcacgac taaaagcttg aattttatga ccatcaggta
    15181 gaagtgccgc ggcaaaatta gtgatttggg cggtcgagcg ataactacga tttaaggtaa
    15241 ttaaattagc tcgcttaaca tgaaaagcct gctttagttt tgctaataga atttgtggtt
    15301 cggtaacatc tttgaacagg gtctgctcac tatcacctag taaggtgaat ttagcgcgag
    15361 gaaaagcatg ttttaggtac attaattgtg caactgagta gtcctgcatt tcatcaacga
    15421 atacatattg gaatttacga ttagtaccac ttccagtaat caaatcacgg agaagcatca
    15481 tgggtgccgc atcttccaaa tgaatctgat gaagttcaat tgcatcagtg aaagctttag
    15541 caactttttg ccaatcgaag tcacctaagt cgatttgact caaaaagtcc gcgtattgag
    15601 aataggaatc gatgaaataa ttattaaaga tagcgtcatc gataatttgg aattctttat
    15661 caactatttg gcgaccgata aaatgatttt cctcatcata tgatttaaag tgacgcgtcc
    15721 ccactaatcc atgatatttt tcgtcgctaa tttggtcgat ttgattttga acccaatcct
    15781 gtttaatttc ctgattaact cgtttttgaa gaagtttgat tagcgcattt ttagttttta
    15841 aaagacgttc tttattgctc atactaagag gaaaggtttc aaagatagct tgaatttgtt
    15901 ctttagaaaa gaaaatttcg ccgcggtaat taatattggt aaatttaatt tctttagtag
    15961 aaagttgttt ttcataagct tgaattaatt caataaaatc ctgactttct ttaaagtcaa
    16021 tgaggttttg ctcgtattca gtgagttggt gttgattttc aaaacggtca aataacgttt
    16081 ggacctgcat gccctccaaa cggcggctga aaaattcggc taaggttagt tgacgcatgt
    16141 ttcgttcccc taaactaggt aaaacgtccg aaatataacg gctatacaac ttattaggag
    16201 aaaaaagtac aatttcatca gcatttaatg aagttcggct atgatataaa agaaaggcga
    16261 tacgttgtag gatagcagag gttttaccac taccagccac gccctgaacg actagaagat
    16321 cactataaac atcgcggatt atgtcgtttt gttccttttg gatagtagcg acgatattac
    16381 gcatgtattc gtcattttgt tcgcctaaag ctcgttgaag aagctcgtcg ccaaccgttt
    16441 cgttagtgtc gaacatatgt tgaatttcac catgattgat agtgaattga cgttttttaa
    16501 tgagttcagt ttccatcatg cccgctgggg tatcatattt aacttttccc agagtaccat
    16561 tgtagtaaat gcttgaaata ggagcacgcc aatcgtaaat taggaaatta ccatcccgat
    16621 cagcaaaaga cgaaattcca atgtaaagcg attcaatatc aggttcatca gcatctttaa
    16681 tatcaattcg tccaaagtag ggtgattttt gaagatcgct taattcatca atttggcgtt
    16741 ttaaaattgc ttcattctcg acagctcgag ctaccagccc tttttgctgt tggatttcag
    16801 catgggtttc gatgcggtca tcggcctcaa tcaagttaac ctttgcattt tgtgagtaat
    16861 ttctttcaac ctggctagtt tcttgatggg ctttatgata taaatcttct gtatgttgtt
    16921 tttgttcgtc gattttttca atgacttccg taactcgttg ctgttcttgt tgttgttcgt
    16981 ccaaatcagc cacctccttg attttaatgc ttgaataatt ctaggtggag gaagaatgaa
    17041 agtcaaccga aagaccagct tgtgagataa agttaaactt attttgacaa ggctaacgtt
    17101 tctaatttaa aatgaaagta gtagttaacc actaacagag agagacagtt gttgagaagt
    17161 ctcatggaag gcgaaatgga ttgatgttta acagggcgaa atcccttatc tttcactaga
    17221 gcggtggctt tataatggag tcacaagtta ggtggtaccg cgatttttcg tcctattatt
    17281 catttttgaa tagtaggatt ttttatatct ggaggaaatt atgacatcta aaaaaattat
    17341 tttaactggt gaccgtccca caggaaaact tcatatcgga cactatgttg gttcacttaa
    17401 aaaccgcgtt caacttcaaa atacaggtga ttatgaaact ttcatcatga ttgctgatat
    17461 gcaggcttta actgataatg cccgtgatcc tgaaaaaatc cgtaatagtc taatccaagt
    17521 tgctttagac tatttagcag tgggcattga tccagctaaa tcgacgatct ttgtgcagtc
    17581 acagattcca gcactaagtg aattgactca acattatatg aatttggtta gcgtagctcg
    17641 tttggaacgg aatccaaccg ttaaaactga aattaaacaa aaggcatttg ggcaaagtat
    17701 tccagctggt ttctttactt atccggttag tcaagctgcc gatattacag cctttaaagc
    17761 agatactgta ccagtagggg atgaccaaga acccatgcta gaacagacgc gtgaaattgt
    17821 acgttctttc aacaatatct accaaaaaga agtgctagtt gaaccagaag gatatttccc
    17881 acctaaagga atgggacgaa ttcctggatt agacggaaat gcaaagatgt ctaaatcatt
    17941 gggtaatgct atttatttgg cagatgacga agaaactatc caaaagaaag ttatgtcaat
    18001 gtatactgat cctcaacata ttcgggtaga agatcctggc catattgaag gtaataccgt
    18061 atttacttac ctagacatct ttgatcctga taagcaaaaa gtccaagaac ttaaagatca
    18121 gtatcaagct ggtggattag gagacgttaa aattaaacgt tacttaaatg aagttctcca
    18181 aaacgaatta cgcccaattc gcgagcgtcg ggaaaggtat gaagcagata ttgacgctgt
    18241 ataccaaatt ctaaaagacg gtagtgacaa ggctaacgcg gtcgcagaac agactttaaa
    18301 ggaagttcga gatgccattg gaattaacta ttttgatcac cgactttaat cgtaaaagcc
    18361 atgcttctaa aagaagtgtg gttttttatt aaggattaat gtaaacgttt gtttttattt
    18421 tagttgatag gcgagatgag ctccttttct aatttaggta atggtaaaat aaaaaaggaa
    18481 tatttcaatt taaatgagga caccaggatg aaaaatttgg taatagtaga tttaggatca
    18541 aactccgctc gaatggcaat taattcgatt gctgatgatg gaacctttcg agaaattaag
    18601 cgagttaaag aagattcacg aatttcagaa ggaatggggc gcgagcgtct tttacgtccc
    18661 caagcaatga atcgtaccat tgcagcccta cgtcgattta aagaaattta tgaagaatat
    18721 cctaatacag aagttagagg gattacaaca gcagctgtta gaatggcgcg aaatcagaac
    18781 gattttttaa atcgcgttaa gcaagaaact ggaattaaat tacacgtctt gtctggcgac
    18841 gatgaggcct attacgatta tttaggtgta atcaattcct tggaagttaa ggattgtttg
    18901 atacttgata ctggtggtgc cagctgtgag ctaattgacg tccataatgg aaaagcgcga
    18961 aatatgatca gtattccgat tggcgctgtg tctttatcgg aacggttccg cttaacggac
    19021 gtagttagag cagataattt atttgccgct gaaatttttg tgaataagca actacgagac
    19081 gtttggtgga ttatggatgc tttcaataaa cccattgttc tcttaggcgg agctaatcgg
    19141 acactggccc gaatgaatcg tcgtcaccaa aaaatttcta gaattaataa tatccacggc
    19201 tatcggctca aaactgaatc ggttaaccga accttcaaat cgttaattac gcggaattta
    19261 gaagctcgta aaaaaatgtc tgggcttgaa actacgcgtg cagatattat cgttggtgga
    19321 atgttaccat tggtgatgtt attacaaatg attgacgctg atcgagtaat tttttctgaa
    19381 agtggcgttc gggaaggaat catttcggag tacatcaatt ttagaaaaga ggaatagttt
    19441 taatgataga aggctaccac aaattaacgc gtcaacagca actcgagcaa ttagcgcagg
    19501 aaactgacgt tgatttgtct gaactaactg aattagctat ggactcaatt catcaacaac
    19561 aaattgaaaa ttatctgact gattttaatt taccagaagg aatcgcagtt aatttagtag
    19621 ttaacggtca agcttatgta gttcccatgg taaccgaaga accgtcagta atagcggcgg
    19681 ctagttatgg agctaaaatg gtccagcgag ccggaggatt ttcggcgaat agtagacgga
    19741 taatgttggg ccagttatta attagcagtg cgcaaccagc ccccataatc gattatgtaa
    19801 aaaaacaaaa atcacattta ttgaaggtcg ctaatgcagc ccacccttcg atgcaagctc
    19861 gtggaggtgg cgcaaaaaat ctacgcattc ggcagttaac cgccacgaaa ctgtcagttg
    19921 atttaatggt tgatacgcgc gaagccatgg gagcgaatac gattaattcc atggtagagg
    19981 ctgttaagaa agatttagta acacaacaaa tcgatgttga tatggcaata ttatctaatt
    20041 tagctgacca agctctgaca gaagttacgt gtcaaattcc agtcaaccaa ctgggagtag
    20101 aagtggctaa aaagattagt ttagctagtg attatgcaca aattgaccca tatcgggcag
    20161 caacgcacaa taaagggatt atgaatggaa ttgatgcggt tgtaatggcg tctggtaacg
    20221 attggcgagc cattgagagc ggagcccacg cttatgctgc tcaaaatggt caatatcaag
    20281 gacttagtac gtgggatgta gttggtgatc aactagttgg cagaatggaa ttaccattac
    20341 cagtggcaac cgttggtggt tcgattggga ttaatactca agctcagctg aacttaaaat
    20401 taatgcaaat taagaacgct aaacaattgg cggaagtaat tgctgcgatt ggtttagctc
    20461 agaatctggc cgctttgaga gctattgtgt cagagggaat tcaatcagga catatgcgac
    20521 tacaggctaa atcactttta atagaacacg gagcgactca agcagagcta ggagatgcgg
    20581 ttaaccgatt agtccaagct gaaagaattg atgccaaaaa tgcccaacaa attattaaac
    20641 agctaagaaa gaaggataat gatgagcaaa gttgaagtaa atgatacagt aaaatcgctt
    20701 cttgaagaag ttaatgcaag ttttccagga gaagtacgga ttggttttgg tgaagaacag
    20761 gccggttttg tgcgtcacga ccaagcccag caatttgttg aagaaggtaa gatgttaatc
    20821 aaggtcaatg atattacggc acctaattac actgcttccc atgagttaat tcacatgtta
    20881 atgattttga aaggttttcc acaactttat ttccaattat caacagggga aaaagatacg
    20941 gataatcaat tgatgttttt gattactgag ctttacgatg taatcgccca cgaagttgtc
    21001 gtcaaagaac aacgtcggca ttatttaatc gatgatgagg tggaagaagc tttctttaaa
    21061 gggattgaag atgccgtaga ggctgaggat gctggtaaag ttgacggatt tagtactatt
    21121 cgtctaataa tgatgatgga tgccattacg ttctatggaa atggtttagc gaactttgaa
    21181 acgcggttga tggatgcttt tccaacaacc taccaagctg ctaaaaaaat tatgcaagaa
    21241 cttgaccaac ggaccatcag taatccgttt gatttccgtc gaaaagtagt caaagctttc
    21301 gaattaattg atactcaatt aaaagaatgg gatttaccag aaattcatgc gatggaattt
    21361 gcgacattgg gaagtgtatt tagtgaacgt caacttcgtt tatcagttaa acaattattc
    21421 caaatcttcc attcagattt acatgaaaaa gctcaagata cacgtggatt tgttggttta
    21481 ggaattagcg accaacaaaa cgcctttgtg gtaccaacac ctaaagatat gccaagtgac
    21541 gaatacttcc gtgaattata tgcaaagaat gttaaagact tctttgaaga aatgaagatg
    21601 ccttatacta ttagataaaa taaaaatcct ggactaaagt aattttagtt acaggatttt
    21661 ttgttagtta tgaaattgcg attaatcttt ctaaactaga caggttttca tgaaaggcat
    21721 gtttagcaat aggggccaag agagtcaacg gtagttttgt taaagtctcg tccactaata
    21781 aagtttgttc gaccaaggtt ctgtcgtctt tgttagttaa atcaaagtgt aattcatatt
    21841 ctaaacgtcc accagtgcta gtgtaaatga tagagttatc ctgactagta accgaaattt
    21901 tttcaaaatt atttaatgca gatgaggaac gtgagattaa aaaataatcg tccttaggtg
    21961 atacagagtt aatgtcaggt acccatttgg aaagattttg tggacttttt aaaattgtgg
    22021 ataatctttc tagattagat tggatgaaga tagtattagt aaataatttt ttcaaagtaa
    22081 aaacctcctt tatt
//
