LOCUS       c00063_NZ_CABK..       15404 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKSY010000063.1 Nosocomiicoccus massiliensis isolate
            MGYG-HGUT-01449, whole genome shotgun sequence.
ACCESSION   c00063_NZ_CABK..
VERSION     c00063_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:02:46
            Original ID  :: NZ_CABKSY010000063.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9277
            Orig. end    :: 24681
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15404
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19277:21803]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12526
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15404
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15404
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(28..1377)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Shikimate_DH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_9"
                     /sec_met_domain="Shikimate_DH (E-value: 1.1e-44, bitscore:
                     142.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="F420_oxidored (E-value: 5.1e-09, bitscore:
                     27.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVIALSINYRKASVDEREQLNFSDHDIVPALHTLRDQKSILEAV
                     IFSTCNRTELYVVTDQVHTGSYYTRNFLSEYFNIPLETVKNVTELKVNDEAIHHLYRVA
                     AGLDSMVLGETQILGQIRDAFILAQEEHTTGKIFNRLFKEVITIAKRGHSETDISKNAV
                     SMSYAAVELAKKIFTNIQDVKVLVLGAGEMSEETLLNLTSNGVSDVTVVNRNPDNGKQL
                     AERYLGQFRPMDELEDALKDTDIVISSTGAPNFIITEEMIKRVRNVDDERSLILIDIAV
                     PRDIDPNVNNVNNVHHYNVDDLSGIVDDNLKKRKEEAKKIEAMIDTSIQEFLNWVEMQG
                     VRPVIEAMRTKALNIHETTFESITNKLPDLTKREKTIISKHMKSIINQMLRDPITYTKE
                     LADERKGAVQLTELEHIFGIESIVEDIHKRHYESLQAIEKLRKEKQNVRK"
     CDS             complement(1480..2067)
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="MELNPNKIEFLISAVAKEQYPETHLPEIAMAGRSNVGKSSFINAI
                     CGRKNIARISSKPGKTVTLNFYNADNQFVFVDVPGYGYAKQSKKERAKWASMIENYFIH
                     RETLHACVQIIDLRHPPTNDDVLMYDFLKQLDIPTIVVATKSDKLPKSKLQKHVSIIRK
                     ELELEPEDVIIPFSSTEKYNVEKVLDAIEERI"
     CDS             complement(2117..3373)
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="MFKFNEDDQDLTCSFCGKNQDQVQKLIAGSGVYICNECIELCHEI
                     IEEELKDAPQEFLTEIPKPGEIQAALDEYVIGQEKAKRALSVAVYNHYKRINHESDDDV
                     EISKSNIALIGPTGSGKTLLAQTLARTLEVPFAIADATSLTEAGYVGDDVENILLRLIQ
                     AADYDIERAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTVASVPPQG
                     GRKHPNQESIQIDTKDILFILGGAFDGIEEIIKRRIGAKVIGFGSGEENVDTNEELMAL
                     VRPDDLQSYGLIPEFIGRVPIIANLEELDTDALTSILTEPKNALVKQYKRMLELDDVEL
                     EFDDDALIAVAKLAIERKTGARGLRSIIEERMVDIMFDVPSNDNISKVRITKDTIVNET
                     DPLVYDAEGNEIHLNEQSA"
     CDS             complement(3488..4780)
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="MSQTQTWEKKEGNVGTLTITVPAEDFDKALDQAFNKVKKDIQVPG
                     FRKGKIPRQMFEKRFGVESLYQDALDIVLPGAYSKAIDETGIKPVDQPSVDVKEIEKGK
                     DLVLELEVTVEPEVELGEYKGLEGKEIDAEVSEDDVNEQIEALLGQYAELVVKEGEVAE
                     GDVANIDFKGFVDGEAFEGGEMEGHDLEIGSGTFIPGFEDQLIGLKAGEEKDVEVTFPE
                     EYQAEELQGKDATFKVKLNEVKEKEAKELTDEFVKEELEGFEGVETADEVKKQIEEDLK
                     NFKEQEKDYELRESLVVQAAENAKMEIPEAMVESEQQRMLQEYEQRLAQQGLNLELFEQ
                     ISGQTKEDLLEQMKDDAFKRVRTGLTLQAIAQAENIEATEEDVDNELQKLADQFQMAKD
                     DIKKVLGDLSVIENDIKNQKAIEFLVDNRKQ"
     CDS             complement(4858..5862)
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="VIYMNNLTSHPRFIKKIERDLKALYHDNDFDLFIEKFSEYSTIVV
                     HIDITLVEMYYDVLIQKNEYEMMYKYAQLCFRTKEMSRDEAELHLNMILQALFNLELYE
                     ELLEWSNIVTVTGKESGMAASLIQFATHCKHYATEKLKKRNTMTQPNENNDEVFNTIDI
                     DIDEYLNAENPTLVIAAVEHLIDLKDESYGDDVYKLLQSERDMSVASLMVIYLKEIEYD
                     GVIHLEKFGETFDAHISEFKQFEKSAKVEPTIRWIVEDGELRFDHEERIQQAIEIFLNI
                     SLLWYPLKVPFTPKELAKGFISYTKMLNNELPMHSFNGYVADWILKIEKEIHK"
     CDS             complement(5846..6457)
                     /locus_tag="ctg63_14"
                     /transl_table=11
                     /translation="MSKFDEMILVVNRKDLFNDEAHAFNGFLSQSDARFNEITKTLDDY
                     EIKRRGDMEEDESYKQLVSYTIVESDHETLVYKRLTGGGESRLHGLHSIGVGGHMNDIE
                     SEENIKEKMFENAARELQEEIGLEKEDLNAFELIGLINDDTNEVGRVHIGLVFKVNVDK
                     EKVFTNEEDTLQLIWSKREELKELGNYETWSELIIRDLYE"
     CDS             6581..7039
                     /locus_tag="ctg63_15"
                     /transl_table=11
                     /translation="MKFTSKDLAINACIAALYVVLTTINPIGHGMIQVRVSEMLAILPF
                     INRKFIPGMIVGVTVANFFSPLGYIDVLVGVGCAVVSYTISYFIKNLWINVVQYAVVCG
                     LIVSLMLKSVLGIPYWPSVIAIFVSTLIVGMIGAVIFNTLKERLKLVD"
     CDS             complement(7075..7284)
                     /locus_tag="ctg63_16"
                     /transl_table=11
                     /translation="MDKDHIILMINEGLDSMDEEFRDEPYDIYFQPNEGQIYMSVSGMA
                     YDGYDKEAYIIAKIENQEVVNWYI"
     CDS             complement(7585..8064)
                     /locus_tag="ctg63_17"
                     /transl_table=11
                     /translation="MKVLIVSDNHREKTMIEKLPKEIDADLYIHLGDSELSSEDAVLEP
                     YEYVKGNTDYDMSFRTEQLYDGLIYFTHGHLYHVNRDRNLLASKAKALGATYALYGHTH
                     IAKVEKINDVYCINPGSISASRSSEPETYAVLDTEQNNVTFYKRDGEVLKQVELE"
     CDS             complement(8073..8663)
                     /locus_tag="ctg63_18"
                     /transl_table=11
                     /translation="MSKIVIASGNKGKINDFKSIFKQFEVVGIQSILEDFNPVEDGETF
                     KDNALIKALEGAKRTNLPVISDDSGLSVEALEGAPGVRSARFAGDDATDQENNEKLLQL
                     MKDEENRSAYFTSVIAVAFPDGTAYTYEGVVFGEILERPVGTNGFGYDPLFQTLDGKKF
                     GELSTDEKAEISHRKRAIDKLLEDENLFNRLQS"
     CDS             complement(8673..9473)
                     /locus_tag="ctg63_19"
                     /transl_table=11
                     /translation="MNNKAIGVMDSGVGGLTVVKELVRQLPREKIVYFGDSLRCPYGER
                     SKEEVLSFTKEIYNFLNRKDIKLFIIACNTATALAISEIRKMIDIPVIGVIKPGSRRAL
                     QISDNDNILVLSTRGTMLSHKYKSTIQKINKSAIVTEHSCPDFVPLIEAFNYKNADIRD
                     NVIHETLKSVKDTNADTVILGCTHYPLIKQAIDDYFSNEKHIVDSGLETARDVSTLLEF
                     KELLSSKDDEIIHEIYVHGDHQQFEEILNEWMPNFKYTIQSVKL"
     CDS             complement(9466..9909)
                     /locus_tag="ctg63_20"
                     /transl_table=11
                     /translation="MPLNMNSASIEKSLRHLSVQVRLYGREILKEYKLSKIQFIALQWV
                     SDSNGQTIGEVAKKLDLAYSTTTDIIDKLECSGFVRRERGHKDKRVVLVKIEQKGTELL
                     SQVIKKRVQFIDEITGDFTEDEKEMLSTLLKRMIKKSESMSYE"
     CDS             complement(10001..10762)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_21"
                     /sec_met_domain="Fer2_3 (E-value: 1e-32, bitscore: 103.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.1e-12, bitscore: 39.0,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00015, bitscore: 13.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAETIKLKIKRQENPESQSYWEDFEIPYRPNMNVISALMEIQRNP
                     VNAKGEKTTPVTWDMSCLEEVCGACSMVINGNARQSCTALIDQYTQPITLEPMSTFPVV
                     RDLQIDRSRMFDSLKRVKAWVPIDGTYDLGAGPRMPEKQRQVAYELSKCMTCGVCLEVC
                     PNVNDKSDFIGAAPISQVRLFNLHPTGRMNKDERLDALMGKGGVSECGMAQNCVKACPK
                     GIPLTTSIASMQRETTFHMFKSFFGSDHEVE"
     CDS             complement(10781..12526)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 287.3; E-value:
                     7.2e-88)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_22"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-88, bitscore:
                     287.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-44,
                     bitscore: 140.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNKVIVVGGGLAGLMATIKAAESGAQIDLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPYKHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVMFS
                     RTPEGLLDFRRFGGTLYHRTAFAGATTGQQLLYALDEQVRKYEVEGLVTKYEGFEFLGI
                     VKDAEGRARGITAQDIKTGEIRSFGADAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAVYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPHYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFTGDDP
                     RKVPMKIFPAVHYSMGGLYVDYDQMTNIPGLFAAGECDYSQHGANRLGANSLLSAIYGG
                     MVAGPNAIDYVNSLETTYEELDSAIFDEAVKVEEDRWENILNMKGEENAYQLHRELGEL
                     MTNNVTVVRENAKLVETDKEIVKLMERYQNINMDDTKQWSNQAAFFTRQLWNMLVLARV
                     ITIGALNRNESRGAHYKPEFPDRNDEEWLKTTKAYYEGPTEAPRFEYEDVDVSLIPPRV
                     RDYTK"
     CDS             complement(12540..13151)
                     /locus_tag="ctg63_23"
                     /transl_table=11
                     /translation="VSKQDSSFFVRRLHSLLGVVPLGVFLVQHLIINNFATRGPEAFNT
                     AAGFMGNLPFVLVLETFVIYLPILFHGIYGVYIAFTAKNNVGQYGTYRNWMFLIQRITG
                     IIAFVFIAIHVYQTRFQVLLGAEVNFDMMADILGSPFWFVFYVVGVLAVVFHFANGLWS
                     FMITWGITQSPKSQQIMSYVAIIVFVIVGFIGVQTLFAFI"
     CDS             complement(13244..15028)
                     /locus_tag="ctg63_24"
                     /transl_table=11
                     /translation="MEKDSQLKLKLSVLPKEPGCYLMKNKRDEIIYVGKAKNLRNRVRS
                     YFTGAHDEKTMRLVSDIVDFDFVITDSEVESLLLENTLIKKHQPRYNILLKDDKSYPFI
                     KITNERHPRLLVTRTVNKRTGKYFGPYPNAYSAHETKRLLDRIYPLRKCDTMPDRLCLY
                     YHIGQCLGPCVYEVTKAENDKMIQGITNFLNGDTESVISELENKMQNAAESLEFERAKE
                     YRDLIHHINATMEKQNMLTSDMTARDVFGFYTYKGWMAVSVLLIRNGKLIEKKAEMFAM
                     NDTVDEEFNRFVFQFYELDSNLKPKEVHLPVSIDPSILNKALPMKIITPKRGGKREMVD
                     LACKNAEVAIKSRFEIIARDERRTTEAIETLGDVLNIETPRHIEAFDNSNIQGADPVSA
                     MVTFIDGKPDKKSYRKYKIRTVEGPDDYESMREVIRRRYSRVLREGLPLPDLIIVDGGI
                     GQMNAAKSILRDELGVFIPVAGVKKDDKHNTAELLYGEGAEIVPLNKTSQTFYLLQRIQ
                     DEVHRFAISFHRNTRKKTAFRSALDDIKGLGPKRKQAMLRAFGSVENMRTKSVEDFQRI
                     GIPQNVSEAIVEKLNNNS"
     CDS             complement(15083..15403)
                     /locus_tag="ctg63_25"
                     /transl_table=11
                     /translation="NTMAIYDVNDSDFKEKISEGVKLVDFWAPWCGPCKMIAPVLEEVA
                     TEVEGKADILKVNVDDNQATAADYGVMSIPTLILMKDGEEVDKVVGFQPKEQLVSLIEK
                     HL"
ORIGIN
        1 ccgactacaa ctgttttcat gattggccta ctttctcaca ttttgttttt cttttcttag
       61 tttttcaatc gcttgtaacg attcataatg tcttttatga atatcttcaa cgatagattc
      121 aataccaaaa atatgttcca gctctgttaa ctgtactgcg cctttacgtt catccgcgag
      181 ttctttcgtg tacgtaatag ggtcacgtaa catttggtta ataatacttt tcatatgttt
      241 agatataatc gtcttttcac gtttagttaa atctggtaac ttatttgtga tgctttcaaa
      301 cgtcgtttca tgtatgttta atgctttcgt acgcattgct tcgattacag gacgtacacc
      361 ttgcatttca acccaattta aaaattcttg aattgatgtg tctatcatcg cttcaatttt
      421 tttcgcttct tcttttctct tttttaaatt atcatcgaca attccactta aatcatcgac
      481 gttataatga tggacgttat ttacattatt aacatttgga tcgatatcac gcggtacagc
      541 gatatcaata agtatgagcg aacgctcatc atcgacgtta cggactcttt taatcatttc
      601 ttcagtaatg ataaagttcg gtgcacctgt acttgagatg acgatatctg tatctttaag
      661 tgcatcttct aattcatcca tcggtctaaa ttgacctaaa taacgttctg cgagttgttt
      721 gccgttatct gggttacggt ttacaactgt aacatcactc acaccattag acgttaagtt
      781 taataacgtt tcttctgaca tttctcccgc accgagtacg agaactttaa catcttgaat
      841 atttgtaaaa atcttcttag cgagttctac cgctgcatat gacatagaca cggcgttttt
      901 agaaatatct gtttcactat gtccgcgttt tgcgattgtg ataacttctt tgaataatcg
      961 attaaaaatt ttccctgtcg tatgttcttc ttgtgcgagt ataaacgcat ctctaatttg
     1021 acctaaaatt tgcgtttcac cgagcaccat tgaatctaac cctgcagcaa ctcggtataa
     1081 gtgatgaatt gcttcatcat tcacttttaa ctctgtcacg tttttaactg tttctagtgg
     1141 tatgttgaaa tactcactta aaaagtttct cgtgtaataa gatcccgtat gcacttgatc
     1201 tgtcacgaca tataattctg ttcggttaca cgttgaaaaa attaccgctt ctaatatact
     1261 tttttgatca cgtaacgtat gaagtgctgg tacgatatcg tgatcactaa aattaagttg
     1321 ttcgcgttca tctacgcttg cttttctata gtttatacta agtgcaatga catgcattta
     1381 gactgcccct tacttaccga ttaaatattt gtttacttat ataatagtat caaatatagg
     1441 accttctttg agtgttttgg ctcaatgttc aataatttgt tagattctct cctcaattgc
     1501 atcgagcact ttttctacat tgtacttctc agttgaagaa aatgggataa tgacgtcttc
     1561 aggttctaat tctaattctt ttctaataat tgatacgtgt ttttgtaatt tacttttagg
     1621 taatttatct gatttcgttg ctacgacaat cgttggtata tcgagttgtt ttaaaaagtc
     1681 atacattaaa acgtcatcgt ttgtcggcgg atgacgtaga tcgataattt gaacacacgc
     1741 atgcaacgtt tctctatgaa taaaataatt ctctatcata gatgcccatt tcgcacgttc
     1801 ttttttagat tgttttgcgt aaccataacc aggaacgtcg acaaacacga attgattatc
     1861 cgcattataa aagtttaacg tcactgtttt acctggttta cttgaaattc tcgcgatatt
     1921 tttacgtcca catatcgcat tgataaaact cgatttaccg acgtttgaac gccctgccat
     1981 cgctatttct ggtaaatgtg tttcaggata ttgttctttt gctactgccg atattaaaaa
     2041 ttcaatttta tttggattta attccattta ctccacctct aaaaaaaggc cgtcttgtaa
     2101 aagacagcct aataaattat gcactctgtt catttaagtg aatttcgtta ccctcagcat
     2161 catatactaa aggatctgtt tcattcacaa tcgtatcttt cgtaattcta actttagaaa
     2221 tattatcatt tgacggtacg tcaaacataa tgtctaccat acgctcttcg ataattgaac
     2281 gtaatccacg tgcacctgtc tttctttcaa tcgcaagttt cgcgaccgca atgagtgcat
     2341 cgtcatcaaa ctctagctca acatcgtcga gttcaagcat gcgcttatat tgcttcacta
     2401 acgcattttt tggctctgtt aaaattgaag tcagtgcgtc tgtatcgagc tcttctaagt
     2461 tcgctataat cggtacacga ccaataaact caggaattaa cccatagctt tgtaagtcgt
     2521 ccggacgaac taatgccatt aactcttcat tcgtatcgac attttcttcg ccgctaccaa
     2581 atccaattac tttcgcacca atacggcgtt taataatctc ttcaatacca tcaaacgctc
     2641 caccgaggat gaacagaata tctttcgtat cgatttgaat cgactcttgg ttcggatgtt
     2701 tacggccacc ttgtggtggt acactcgcaa ctgttccttc taaaatttta agtaatgctt
     2761 gttgtacccc ttcaccggaa acatcgcgtg taattgacgt attttcactt ttacgagcaa
     2821 tcttatcgat ttcatcgacg taaataattc ctttttcagc acgctcaata tcataatccg
     2881 ctgcttgaat taaacggagt aaaatatttt caacgtcatc tccaacgtaa cccgcttcag
     2941 ttaaacttgt cgcatccgca atcgcaaatg gcacttctaa tgtgcgtgca agtgtttgtg
     3001 cgagtaacgt tttacctgaa cctgttggtc caattaaagc gatgttactt ttagatattt
     3061 caacatcgtc atcactttca tggttaatac gtttatagtg gttatacacc gccacactaa
     3121 gtgcgcgctt tgctttttct tgtccgatga catactcatc aagcgctgcc tgaatttcac
     3181 ctggctttgg aatttcagtt aaaaactctt gtggtgcgtc ttttaattct tcttcaatta
     3241 tttcgtgaca taattcaata cactcattac aaatgtatac gccacttcct gcgatcagtt
     3301 tttgaacttg atcttggttt ttaccacaga aactacatgt tagatcttga tcatcttcgt
     3361 taaatttaaa catgtataca ccgacctttc gctcttacgt atattactat actataccga
     3421 ctctttcaaa taaattgtat tgataaaaaa actctataca catccatgta tagagctttt
     3481 tttgatttta ttgttttctg ttatctacta agaactcaat tgctttttgg tttttaatgt
     3541 cattttcaat gacagataaa tcaccaagaa cttttttgat gtcgtctttc gccatttgga
     3601 attggtccgc taacttttgt aattcgttat cgacatcttc ttcagtcgct tcaatgtttt
     3661 cagcttgtgc aattgcttgt aaagttaaac cagtacgtac acgtttaaac gcgtcgtctt
     3721 tcatttgctc gagtaagtct tctttcgttt gaccagagat ttgctcgaat aactctaagt
     3781 ttaacccttg ttgagcaaga cgttgttcgt attcttgaag cattctttgt tgttcacttt
     3841 caaccattgc ttcaggaatt tccattttcg cattttcagc tgcttgaaca acgagagatt
     3901 ctcttaattc gtaatctttt tcttgttctt taaagttctt taagtcttct tcgatttgtt
     3961 ttttaacttc gtcagctgtt tctacgcctt caaaaccttc taattcttct ttaacaaatt
     4021 cgtcagtcag ttcttttgct tctttttctt ttacttcgtt taattttact ttaaacgttg
     4081 cgtctttacc ttgaagttct tctgcttgat actcttctgg gaaagtaact tctacgtctt
     4141 tttcttctcc agctttaaga ccgattaact gatcttcaaa tccaggaatg aatgtaccac
     4201 taccgatttc aaggtcgtga ccttccattt ctccgccttc aaatgcttct ccatcaacga
     4261 agcctttgaa gtcgatgttt gcaacgtcac cttcagcaac ttcgccttct tttacgacaa
     4321 gctcagcata ttgaccgagt aacgcttcga tttgttcgtt tacatcgtct tcagatactt
     4381 cggcatcgat ttctttacct tcaagtcctt tgtattcacc gagctctact tctggctcta
     4441 cagttacttc taattcaagt actaaatctt tgcctttttc gatttcttta acatcaacgc
     4501 taggttgatc gactggttta atacctgttt catcaattgc tttgctataa gcgcctggta
     4561 aaacgatatc taaagcgtct tgatataatg attcaacgcc aaagcgtttt tcgaacattt
     4621 gacgaggaat tttacctttt ctaaatccag gtacttgaat atcttttttt actttgttga
     4681 atgcttggtc taaagcttta tcaaaatctt cagcaggcac tgtaattgtt aatgtaccta
     4741 cgtttccttc tttcttttcc caagtttgtg tttgagacat aatcatttcc tccgttattt
     4801 tacattttaa ttaacctatt cattgtaaca taatcgattt ttcaataaaa gtatcgacta
     4861 cttatgaatt tctttttcaa tttttagtat ccaatccgcc acataaccat taaacgaatg
     4921 catgggtaat tcgttattta acatttttgt atacgatata aacccttttg ctagttcttt
     4981 aggtgtgaac ggcactttaa gaggatacca tagtaagcta atgtttaaaa atatttcaat
     5041 cgcttgttgt atgcgttctt cgtggtcaaa gcgaagctcg ccgtcttcga cgatccaacg
     5101 aatcgtcggt tcgacttttg cagatttctc aaattgttta aattcactaa tatgtgcatc
     5161 aaacgtttca ccaaattttt ctagatgaat gacaccgtca tactctattt cttttaaata
     5221 aatgaccatg agtgatgcta cactcatatc tctttccgat tgaagtaatt tataaacatc
     5281 atcaccatat gactcatctt ttaaatcgat taaatgctca accgcagcga tgacaagtgt
     5341 cggattttcg gcgtttaaat actcatctat atcaatatct atcgtattaa acacttcatc
     5401 attattttca tttggttgcg tcatcgtatt tcttttcttt aatttttccg tcgcataatg
     5461 tttacaatgt gtcgcaaatt gtataagtga ggctgccata ccactctctt tacctgtcac
     5521 agtaacgata tttgaccatt caagtaattc ttcgtataac tctaaattaa ataacgcttg
     5581 aaggatcatg ttcagatgaa gttccgcttc atcacgtgac atttctttcg ttcgaaaaca
     5641 aagttgtgcg tatttataca tcatttcata ttcatttttt tgaattaaca catcataata
     5701 catttcgact aaagtaatat ctatatgaac gactattgtg ctatattccg aaaacttttc
     5761 tatgaataaa tcaaaatcat tatcatgata gagtgctttt aaatcacgtt caattttttt
     5821 aataaaccgt gggtgtgacg ttaagttatt catataaatc acgaatgatg agttcactcc
     5881 acgtttcgta gtttcctaac tcttttaact cttctctttt tgaccatata agttggagcg
     5941 tgtcttcctc attcgtaaat actttttctt tgtctacatt cactttaaat acgagtccaa
     6001 tatggacacg tccgacttca tttgtatcat cgttaattaa accgattaat tcaaacgcgt
     6061 ttaagtcttc cttttctaag ccaatttctt cttgtagttc acgcgctgcg ttttcaaaca
     6121 ttttttcttt aatgttttct tcagattcaa tatcgttcat atgtccaccg acaccgattg
     6181 aatgaagtcc atgtaaacga gattcaccgc cacctgttaa acgtttataa acgagcgttt
     6241 catgatcact ttcaacaatc gtatatgaca cgagctgttt atatgactcg tcttcttcca
     6301 tatctccacg gcgtttaatt tcatagtcat ctagcgtctt cgtaatttca ttaaaacgtg
     6361 catcagattg acttaaaaaa ccgttaaacg catgtgcttc atcattaaat aaatcttttc
     6421 tatttactac taaaatcatt tcatcgaatt tactcatcta tatactccta atcttttact
     6481 gtcttcatta tactatagta atttttaatg tgttttgcta taatttcaca ttgaaacagg
     6541 ttcgaaaact tccctgtata aaaaactaag gagaattaca atgaaattta cttcaaagga
     6601 tcttgcaatt aatgcatgta tcgctgcttt gtatgtcgtc ttaacgacaa ttaacccaat
     6661 cggtcacgga atgatacaag tccgcgtgtc agaaatgctc gcaatacttc cgtttataaa
     6721 ccgaaaattt atacctggaa tgatcgtagg tgtaacagtt gcaaacttct tttcaccact
     6781 cgggtatatc gacgttctcg tcggggtcgg atgtgcggtt gtttcgtata caatcagcta
     6841 cttcattaaa aacttatgga taaacgtcgt acaatacgca gttgtatgtg ggcttatcgt
     6901 atcacttatg ctgaaatccg tattagggat accatactgg ccatcagtca tcgcgatatt
     6961 cgtatcgaca ttaatcgttg gtatgatcgg tgcagtcata tttaatacac tcaaagaaag
     7021 actaaaatta gtagattaat ataagcagta aagcacccat attttgggtg ctttttaaat
     7081 ataccaattc acaacttctt ggttttcaat tttcgcgatt atatatgcct ctttatcgta
     7141 accgtcatat gccataccac ttacagacat ataaatttgc ccttcattcg gctgaaaata
     7201 aatgtcataa ggttcatctc taaattcttc atccatacta tctaagcctt cattaatcat
     7261 taaaataata tgatctttat ccatacgtaa actcctttat atgtttttta atacgtgtat
     7321 atcgtatacc caacataatc agtaaagtat tcttaaatta cgcataaata aagatattaa
     7381 agaaaataaa aaagcctgta acttaaaagt tacaggcttt aattacgtcc tgggagggat
     7441 tcgaaccccc gaccgatggc ttagaaggcc attgctctat ccagctgagc taccaggacc
     7501 tatcaatgaa cacaataacc attatagtaa atgccacgtc taaatgtcaa catgtttttt
     7561 tataattata cgtgtttcat tgatttactc gagttcaact tgttttaaca cttctccatc
     7621 tctcttataa aacgttacgt tattttgttc agtgtctaat actgcatatg tttctggctc
     7681 agaacttctt gaagcggata ttgatcctgg gtttatacag taaacgtcat taattttttc
     7741 aactttagcg atatgcgtat gaccgtataa tgcatatgta gcaccgagtg ctttcgcttt
     7801 tgaagcgagt aggtttcggt cacggtttac atggtataaa tggccgtgtg taaaataaat
     7861 aagaccatca tacaattgtt cagttctaaa actcatatca taatccgtat ttcctttaac
     7921 atactcatac ggttctagta cagcatcttc tgatgacagt tcactatcac cgagatggat
     7981 gtatagatca gcatctattt ctttaggcaa tttttcaatc attgtttttt ctctatggtt
     8041 atcactgacg attaatactt tcattatttc acctaacttt gaagtctatt aaataagttt
     8101 tcatcttcta ataacttatc gatggcacgt tttcgatgtg aaatctcagc tttttcatcc
     8161 gttgataact caccaaattt tttaccatct aacgtttgaa agagcgggtc gtaaccaaat
     8221 ccattagtgc caacaggtct ttctaatatt tcaccgaata caacgccctc atacgtatac
     8281 gctgttccat ccggaaatgc gaccgcaata acagaagtaa agtatgcgga tctgttttct
     8341 tcatctttca ttagttgtaa taacttttcg ttattttctt gatctgtcgc gtcatctcca
     8401 gcaaaacgtg cagatctaac gcctggtgca ccctctaacg cttctactga taatcctgaa
     8461 tcgtcactga ttacaggtaa attcgtacgt tttgcgcctt ctaatgcttt tattaatgca
     8521 ttatctttaa acgtttcacc atcttctaca ggattaaaat cttctaaaat agattgaatc
     8581 ccaacgactt cgaactgttt aaaaattgat ttgaaatcat taattttacc tttattacca
     8641 cttgcaatta ctattttact cataaaatac tcctataatt taactgattg aattgtatat
     8701 ttaaaattcg gcatccattc gtttaaaatc tcttcgaatt gttgatgatc accgtgaacg
     8761 taaatctcgt gtatgatctc atcatctttt gaactgagta gctctttaaa ctctaataac
     8821 gtactgacgt ctctcgcagt ctctaatcca gagtcgacga tatgcttttc atttgaaaaa
     8881 taatcatcaa tcgcctgttt gattaacgga tagtgagtgc acccgagaat tactgtatct
     8941 gcatttgtgt ctttaacgct ctttaatgtc tcgtgaatta cattatctcg tatatcagca
     9001 tttttataat taaatgcttc gataagcggt acaaaatctg gacacgaatg ctctgtgacg
     9061 attgctgatt tattaatctt ttgtatcgtc gacttatatt tatgtgaaag catcgtacct
     9121 ctcgtagata atacgagaat attatcattg tctgaaattt gtaatgcacg tctagatccc
     9181 ggtttaataa caccgatgac tgggatatct atcatttttc taatttcaga aatagcgaga
     9241 gcagtcgctg tgttacaagc aatgataaac agctttatat ctttacgatt taaaaaatta
     9301 taaatttctt tcgtgaacga taatacctct tctttcgagc gctcaccata cggacatctt
     9361 aaactatccc caaaataaac aatcttttct ctcggtagtt ggcgtacgag ttcttttaca
     9421 actgttaaac caccgactcc agaatccatg acgccgattg ccttattatt catatgacat
     9481 cgactcactt tttttaatca ttcgtttaag caaagtggat aacatttctt tctcatcttc
     9541 agtaaaatca cccgtaattt catcgatgaa ctgtacgcgc tttttaataa cttgagacaa
     9601 tagttccgta cctttttgtt caatttttac gagaacgaca cgtttatctt tatgaccacg
     9661 ctctctacgt acaaaaccac tacattcgag tttgtctata atatctgtcg ttgtcgaata
     9721 cgcaagatct aactttttag cgacctctcc gatcgtctga ccattagaat cactcaccca
     9781 ttgtagtgcg ataaattgaa tttttgataa tttatattct tttaatattt cacgaccata
     9841 cagccttact tgcaccgata aatgcctcaa tgatttttca atcgatgcac tattcatatt
     9901 taaaggcata cttatcccca ccttaaccta tatggctata ttatacatga attaaaaatt
     9961 gaaataaaaa aagatgtgtc gaaacacatc tttttgtata ttattctact tcatggtcac
    10021 taccaaagaa tgatttaaac atatggaatg tcgtttctct ttgcatagat gcgatagaag
    10081 ttgttaatgg aatacctttt ggacatgctt taacacaatt ttgtgccata ccacattcag
    10141 atactccacc tttgcccatt aacgcatcta atctttcgtc tttgttcata cgtcctgttg
    10201 gatgtaagtt aaatagacgc acttgtgaaa tcggtgctgc accgataaag tcagatttgt
    10261 cgtttacgtt tggacacact tctaaacata caccacatgt catacattta gaaagttcat
    10321 atgcaacttg acgttgcttt tcaggcatac gaggacctgc accaagatcg tatgtaccat
    10381 cgattggtac ccaagctttc acacgtttta agctatcgaa catacgtgag cggtcaattt
    10441 gtaagtctct aacgactggg aatgtgctca tcggttctaa cgtgattggt tgcgtgtact
    10501 ggtcaattag cgcagtacat gattggcgtg catttccgtt aataaccatt gaacacgcac
    10561 cacaaacttc ttctaaacaa ctcatgtccc aagtgactgg tgttgttttt tctcctttag
    10621 cgttcacagg gtttctttga atctccataa gcgcactgat gacgttcata tttggtctgt
    10681 aaggaatttc aaagtcttcc cagtagcttt gtgattctgg gttttcttgg cgtttgattt
    10741 ttaatttaat agtttctgcc attttaatac tcctctcaga ttacttagta tagtcacgta
    10801 cgcgtggtgg gatcaggctt acatcaacgt cttcatattc aaaacgtggt gcttctgttg
    10861 gcccttcgta atacgctttt gtagttttta gccattcttc atcgttacgg tcagggaatt
    10921 ctggtttgta gtgtgcacca cgagattcgt tacggtttaa tgcaccgatt gtaatcacac
    10981 gtgctaacac taacatgttc cataattgtc ttgtgaagaa tgctgcttgg ttactccact
    11041 gctttgtatc gtccatatta atgttttgat atctttccat taatttaacg atttctttat
    11101 ctgtttcaac taattttgcg ttttctctaa caactgttac gttgtttgtc attaactcac
    11161 caagttcacg gtgtaattga tatgcgtttt cttcaccctt catgttaagg atgttttccc
    11221 agcgatcttc ttcgactttt actgcttcat cgaaaattgc actatctaac tcttcgtaag
    11281 tcgtttctaa agagttcaca tagtcgatcg cattaggtcc agcaaccata ccaccgtaaa
    11341 ttgctgataa taatgagttc gcgcctagtc ggtttgcacc gtgttgtgaa taatcacact
    11401 cacctgctgc aaatagacca gggatgtttg tcatttgatc gtaatctaca tataatccac
    11461 ccattgagta gtgtactgct gggaagattt tcatcggaac tttacgtgga tcgtctccag
    11521 taaatttctc atagatttcg ataattccac cgagtttaac atctaactcg tgtggatctt
    11581 tatgtgaaag gtctaagtaa accatgtttt ctccgttaat acctaacttt tggtttacac
    11641 atacatcaaa gatttcacgc gtcgcgatat ctcttggtac gaggtttccg tagtgtggat
    11701 atttctcttc taagaaatac caaggtttac cgtctttgta tgtccaaata cgtccacctt
    11761 caccacgtgc tgactcactc ataagacgta atttgtcgtc accaggaatt gctgttgggt
    11821 gaatctggat gaattcaccg tttgcgtata ctgcaccttg ttggtacacg attgacgctg
    11881 ctgatccagt gttaatcatt gagttcgtcg atttaccaaa gataattcca ggtccacctg
    11941 tagccataat taccgcgtca gcaccgaacg aacgaatttc acccgttttg atgtcttgcg
    12001 ctgtaatacc acgtgcacga ccttcagcat ctttaacgat acctaaaaat tcaaatcctt
    12061 cgtattttgt tactaagccc tcaacttcat attttctcac ttgctcatca agtgcatata
    12121 ataactgttg accagtcgtt gcacctgcga atgccgtacg gtgatatagc gttccaccga
    12181 aacgacggaa gtcaagtaaa ccttctggcg tacggctgaa cataacgccc atacgatcga
    12241 gtaagtgaat gatttttggt gctgcttcag tcattgcttt aaccggtggt tggtttgcta
    12301 agaagtctcc accgtacacc gtatcatcaa agtgtttata aggtgaatct ccctcacctt
    12361 ttgtatttac ggcaccgtta attccacctt gtgcacatac agagtgtgaa cgtttaaccg
    12421 gaacaattga aaatagatca atttgtgcgc cgctttctgc tgcttttatc gttgccatta
    12481 gacccgcaag tccaccaccg acaacgataa ctttattatt tgccattagt gacactcctt
    12541 taaataaatg cgaataatgt ttgaacgccg atgaatccaa caattacaaa aacgataatc
    12601 gcaacatagc tcattatttg ctgagatttt ggtgattgtg taattcccca tgtaatcatg
    12661 aatgaccata atccatttgc gaagtggaat acgaccgcaa gaacaccgac tacatagaat
    12721 acaaaccaaa acggactacc gagaatatct gccatcatat caaagtttac ttcagcacct
    12781 agtaatactt ggaaacgtgt ttgataaacg tgaattgcaa taaatacgaa tgcaataatt
    12841 cccgtaattc tttgaataag gaacatccag tttctgtatg taccgtattg acctacgttg
    12901 ttttttgcag taaatgcaat atacacaccg taaataccat ggaataaaat cggtaagtaa
    12961 atgacaaatg tttcaagaac taaaacaaaa ggcaagttac ccatgaatcc agcagccgtg
    13021 ttaaatgctt ctggtccacg tgttgcgaag ttgttgataa ttaggtgttg aactaagaac
    13081 acaccaagtg gcacaactcc aagcaatgaa tgcaatcttc tcacaaaaaa gctcgaatct
    13141 tgtttagaca ctattgtccc ccctaaccaa attaacaaat catagtgttt gctttatatt
    13201 ttacgactca ttatcagtta aatcaagaca ctataaagcc ttttcagcta ttattgttaa
    13261 gtttttcaac aattgcttct gaaacgtttt gtggaatccc aattctttgg aaatcttcaa
    13321 cggattttgt cctcatattt tctactgatc caaatgcacg taacatcgct tgtttacgct
    13381 ttggaccaag ccctttaata tcgtctaatg cagaacgaaa cgctgttttt ttacgcgtgt
    13441 ttcgatggaa cgatatcgca aaacggtgca cttcatcttg tatacgttgt agtaaataaa
    13501 acgtctgaga agttttattt aaagggacga tttctgcacc ttcaccatat aacaactctg
    13561 ctgtattatg tttgtcgtct ttttttacac cagcaacagg aataaatacg ccgagctcat
    13621 ctcttaatat acttttcgca gcgttcattt gtccgatacc accgtctacg ataatgagat
    13681 ccggaagcgg taaaccttca cgtaatacac ggctataacg tctgcgaatt acttctctca
    13741 tcgattcgta atcatctggt ccttcaaccg tacgaatttt atattttcta tatgactttt
    13801 tatctggctt tccgtcaata aatgtgacca tcgcactgac agggtctgcg ccttgaatgt
    13861 tcgagttatc aaacgcttcg atatgccttg gtgtttcaat attcagtacg tctccaagtg
    13921 tttcaatcgc ttctgtcgtc cgtctttcat ctctcgcgat aatttcaaag cgacttttaa
    13981 ttgcaacttc ggcattttta cacgctagat caaccatttc acgtttaccc ccgcgttttg
    14041 gtgtgattat tttcatcggt aatgctttat ttaaaatcga tggatcgatt gatactggta
    14101 aatgaacttc ttttggtttt aagttcgaat ctagctcata gaactgaaag acgaaacggt
    14161 taaattcttc gtcgactgta tcattcattg caaacatttc tgcttttttt tcaatcagtt
    14221 taccgttacg aattagcaag acactaactg ccatccaacc tttatatgtg taaaatccga
    14281 acacatctct cgctgtcata tcgctcgtta acatattttg tttttccata gtcgcattta
    14341 tatgatgtat taaatcacga tattctttcg cacgttcaaa ctctaatgat tctgctgcat
    14401 tttgcatttt attttcaagt tcagatatga ctgattcagt gtcaccgttt aaaaagtttg
    14461 taataccttg aatcatttta tcattttctg cttttgttac ttcatacaca catggtccta
    14521 ggcactgccc aatgtggtaa tacaaacata atctatccgg catcgtatcg cattttcgta
    14581 acggataaat ccggtcgagt aatcgttttg tttcatgtgc actataagcg tttggatatg
    14641 gaccaaaata tttacctgtt cgtttattaa cagtacgtgt aacgagtaat cgtggatgtc
    14701 gttcattcgt aatttttata aacggataac ttttatcgtc ttttaataaa atgttatagc
    14761 gtggttgatg cttttttatt aatgtatttt ctagtaataa tgactcaact tcagaatctg
    14821 tgataacaaa gtcaaaatcg acgatgtcac tcacgagtcg cattgttttt tcatcgtgtg
    14881 caccagtaaa ataggaccgc acgcgatttc ttaagttttt agctttaccg acgtaaataa
    14941 tttcatcgcg cttatttttc attaaataac agcctggttc tttcggtaac accgaaagtt
    15001 ttaactttaa ctgtgaatct ttttccataa gtgatccctc aattgatata aaaaaagccg
    15061 ctcatcgcgg cttagtcgta tattataagt gtttttcgat taatgaaacg agttgctctt
    15121 ttggttggaa gccaacaact ttgtctactt cttctccgtc tttcataaga attaaagtag
    15181 gaatagacat aactccgtaa tcagctgcag ttgcttggtt gtcatccaca tttactttaa
    15241 ggatgtctgc tttaccttca acttctgttg ctacttcttc tagtaccggt gcaatcatct
    15301 tacaaggtcc acaccaaggt gcccagaaat ctacaagttt aacaccttcg ctaatttttt
    15361 ctttaaaatc tgaatcattt acatcataaa ttgccatagt atta
//
