LOCUS       c00205_NZ_BKAJ..       14120 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BKAJ01000205.1 Reyranella soli strain NBRC 108950 sequence205,
            whole genome shotgun sequence.
ACCESSION   NZ_BKAJ01000205
VERSION     NZ_BKAJ01000205
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:01:08
            Original ID  :: NZ_BKAJ01000205.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2198
            Orig. end    :: 16318
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14120
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12198:14218]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12020
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..14120
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14120
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(2043..2834)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg205_4"
                     /sec_met_domain="Abhydrolase_1 (E-value: 1.3e-14, bitscore:
                     44.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIERSFVRIKSGLVHVAACGAGRPILLLHQTPRSWDEYREVLPLL
                     GARYRAIAMDTVGFGDSEPLPDGSDSIEAWAAAAHEVLAALGHARAVIAGHHTGAAVAV
                     EMAASQPERVEALVLSACPYVDAARRAREPGKRVIDEVAAHHDGRHLQELWARRQPFYP
                     EGRGDLLERFIVDALKAGPRAAEGHRVVGRYVMEPRLPLVRCPTLVIAPMADPHAHPHA
                     PAVAASIAGSKLIEIEAGTVPLPDHMPHAFAAAIDQFLSSH"
     CDS             2872..4026
                     /locus_tag="ctg205_5"
                     /transl_table=11
                     /translation="MKNSIAAAVVAASLGFATAAQAEITVGFITSQSGPGSSIGVLYDR
                     GMKAAVEYASSVGAEKVKLIQLDDGSDPSSATRNARKLVEENKVDLLIGTSTAASTSAM
                     VPIANELKVPMIAISPISVAANDAGDRWAIVMPQPPTLMVKVVVDRMKRDGVKQFAYIG
                     FSDAWGDLVYNGAQKPAEADGLKILTNERYVRTDTSVTGQVLKMMATKPDAVLLGGAAT
                     QGALPPLALAERGYKGPLYGTPALLNTDFIRVGGKAVEGVQVSAGPVVVAEQLPDTHFS
                     KKISMDFRAAYQKANGSPTSDAFSAYSFDAWLVFLDAAKRAMATGAKPGTPEFRVALRN
                     AIFNTNDLVGTHAIYNYKPSDSYGVDERALVMVRLVNGQWKYEP"
     CDS             4045..5091
                     /locus_tag="ctg205_6"
                     /transl_table=11
                     /translation="MNGEIAAILAMDGIASGAIYVLIGLGLVLIFAVTRVIFVPFGDIA
                     AFTALSLASLETGGRPGTVGLVAVLAVLATAVEAVALVRNRAFHRLPRALLFYLVLPLI
                     PAAAVWFAAGTTFSMPVRIVLSLALVLPIAPLLDRIVFRPIADASVLLLLTVAVALHFA
                     LSGLGLMFFGPEGVRTKPLTDAVFDVAGLIVNGQMLLILAASIVFCGLLFLYFEFTIQG
                     KALRATAVNRVGARLVGIRPTSTGTIAYLLASLLAGISGVLIAPVTTIFYDSGFLLGLK
                     AFVGAIIGAMVSYPVTALGAVMVGLLESFTSFWLSAYKEVLVFSLLIPVLLWRSLAFAG
                     TEEEEAEE"
     CDS             5088..6857
                     /locus_tag="ctg205_7"
                     /transl_table=11
                     /translation="MTRLQFHLVAAAGVLLLALAPALLSPFSITLMNFIGIYALAVLGL
                     VLLSGIGGMLSFGQAAFVGIAAYATAWLTVKAGYSPWIGLVVGVVLTGLVAAILGAVTL
                     RLGGHFLSLSTIAWGLATYFLFGNVPMLGQYNGISEIPPISIGGYALSSSNSIYYLIWV
                     FVIVSLVLSANLLDSREGRAVRALRGGQVMTESLGINPFRVKLITFVIAALLSALSGWL
                     YAHMSRFVSPAPFDVSVGILYLLMAMVGGMAYLSGAIVGAAVVTLLKNSIQDWLPVISP
                     GASGQLEVIVFSVLFILVLQRARAGIVPLALRWLPRVQPTPPLASGSLVHRQQPERGQP
                     ILTIAGATRRFGGLLAVDNVSFEVKAGEILGLIGPNGAGKTTMFNLITGALPLNQGRIS
                     FLGQDISRHAQRQIARAGIARTFQHVKLRKTMTLLDTVLLGTYGRTSSGFFAGVLRLDR
                     AEEARAQAEAMRQLQRVGLADRAFELAGNLPLGNQRLLEIARALAADPALLVLDEPAAG
                     LRSAEKAELAHLLEALRAEGLSILLVEHDMDFVMGLVDRTVVMDFGAKLCEGTPAVVRS
                     DPRVQEAYLGGVA"
     misc_feature    6150..6152
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     misc_feature    6288..6290
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             6859..7572
                     /locus_tag="ctg205_8"
                     /transl_table=11
                     /translation="MALLSIDQVSVAYDKVEAVRGVSLAIEPGQIVTVIGPNGAGKTTL
                     LGAAIGLLPWRGRMSFDGIDLRRLDVEARIERGFCLVPETRELFGDLSVSDNLLLGGYS
                     RRRDSAGLKQSLADVYKRFPRLDERRNQKASTLSGGERQMLALGRALMAKPRLLMLDEP
                     SLGLAPIIVREVFKIIASLRELGVSILLVEQNARAALETADFGYVLETGEIVHSGAAAD
                     LMHDPRVTASYLGGH"
     misc_feature    7153..7155
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             7710..10004
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg205_9"
                     /sec_met_domain="Oxidored_FMN (E-value: 3e-67, bitscore:
                     217.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKVAVLGAGPAGLYFAISMKRRNPGHEITVFERNKPDDTFGWGVV
                     LSAETLDNLAANDAVSAAWIREYFAYWDDIAVIHKGVRTVSTGHGFCGIGRKRLLLLLQ
                     RRAGDLGIELKFETEIDDPRPFMESHDLVIAADGLNSRSRAAFAEVFKPDIDVRKCKFV
                     WLGTRQKFDDAFTFIFEETEHGWVWAHAYQFEPETATFIVECSEETWAAWGFSDMTRKQ
                     SIAACERIFAKHLGGQSLISNASHLRGSAWINFPRVLCERWSHKNLALLGDASASAHFS
                     IGSGTKLALESAVALADYLHSEPGLTAAFEKYESARRTEVLRLQSAARNSLEWFEEVER
                     YLDLDPVQFNYSLLTRSQRISHENLRMRDPAWLGGAEAWFQRRAGNTDNLRRAPMFAPF
                     QLRDLKLANRVVVSPMAQYKAVDGCPTDWHFAHYAERAKGGAGLIYIEMTCVSPEGRIT
                     PGCTGFYAPEHEVAWKRLVDFVHAETEAKICAQIGHSGAKGSTQLGWQQIDAPLKSGNW
                     PLMAASEVPWSPENQVPKAMDRADMARIREQFVASAEMAARCGFDMLEIHAAHGYLLSS
                     FITPITNHRTDEYGGALENRLRYPLEVFQAVRAVWPAHKPISVRISANDWMGDEGVTPA
                     EAVEIARLLQAAGVDICDVSAGQTSIRGRPVYGRMFQTPFSDRIRNETGMATMAVGNIY
                     EPDHVNSILLAGRADLVCLARPHLADPYWTLHAAVQLGDRDVKWPDPYLNGRDQLYRLA
                     DRGGATMGPKV"
     CDS             10001..10759
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: adh_short"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_10"
                     /sec_met_domain="adh_short (E-value: 2.1e-59, bitscore:
                     190.2, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGKHALVTGGGTGVGRAVALALAKAGVSVTICGRRKAKLEAVA
                     GENARIFPIAADVTDEAAMTALYAEAEELRGPFDIVVANAGGAESSPAHKTSLADWQRA
                     LDLNLTGSFLTVKPALGGMTKRKAGRIVFVASTAGLKGYAYVAPYVAAKHGVVGLMRAL
                     ATETVKSGVTVNAVCPGFIETDMLEESVQRIVRTTGRTVEQARTSLASTNPQGRFIQPK
                     EVAAAVLWLCSEAAGSVTGQALSLSGGETW"
     CDS             10753..11211
                     /locus_tag="ctg205_11"
                     /transl_table=11
                     /translation="VVSGPVSASKEKLRLWIRLLRASRTIEGELRERLSTEFDTTLPRF
                     DVMAALYRVPDGMLMSDLSRFLLVSNGNVTGIVDRLVSEGLVQRGQRNGDRRTSIVQLT
                     KAGKDTFRTMAAAHERWVGELLAGVTKSDAKQLTSMLKAFRSNWEGRE"
     CDS             11208..12020
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg205_12"
                     /sec_met_domain="ECH_1 (E-value: 5e-44, bitscore: 140.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKMAGFRPKHFLWQVEGKVAHIQLDRPERKNPLTFDSYAELRDT
                     FRELRYAEDVDVVVFLPNGGNFCSGGDVRDIIGPLVAMEMKELLNFTRMTGDLVKAMLA
                     CGKPIITAVDGVAVGAGAIIVMASDIRIATPEAKTAFLFTRVGLAGCDMGACAILPRII
                     GQGRAAELLYTGRSMSAAEGERWGFYNRLVDAGALEPDALDMARRIASGPTFAHGITKT
                     QLNQEWSMGLDQAIEAEAQAQAICMQTRDFERAYRAFVAKQTPVFEGT"
     CDS             12023..13642
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 263.3; E-value:
                     1e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg205_13"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-81, bitscore:
                     263.3, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 2e-25, bitscore:
                     79.6, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGPSAHIDTFSRDNLPPAAQLPDFRLAGFDYPERLNVAVELTDR
                     MVQKGFGDNTALIGNGRRRTYKELTDWTNRLARALVENYGVRPGNRVLVRAANNPAMVA
                     CWLAATKAGAVVVNTMPMLRAGELAQIVDKAKIALALCDTRLMDELVACAKDSRFLEQV
                     VGFDGTANHDAELDRVALTKPVRFEAVATGRDDVALLGFTSGTTGVPKATMHFHRDLLI
                     IADGYAKDVLGVTPDDVFVGSPPLAFTFGLGGLAIFPLRFGAAATLLENASPANMVEII
                     ETYRATISFTAPTAYRAMLTAMDAGADLSSLRIAVSAGETLPAPVFNDWLAKTGKPILD
                     GIGATEMLHIFISNRLDDLAPGSTGKPVRGYEARVVDEAMKEVPRGTVGRLAVRGPTGC
                     RYLADERQRNYVRDGWNLTGDSFVQDEAGYFHFAARSDDMIISAGYNIAGPEVEAALLT
                     HADVAECAVIGIADAERGQIVQAHVVLADGVAPDLDTTKRLQDHVKATIAPYKYPRSVK
                     FTPALPKTQTGKIQRFLLKNQG"
     CDS             13645..14046
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 73.6; E-value:
                     4.4e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg205_14"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 1e-23, bitscore:
                     73.6, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHTILQPAGWAKPNGYANGVAAQGRFVFVGGQIGWNGQSRFET
                     DDLVGQVRQTLQNVVDVLAEAGAKPEHVTTMTWYLTNKKDYLGNLAGIGKAYREIMGRN
                     FPAMAVVEVTALVEDRAKVEIQAMAVVPM"
ORIGIN
        1 agcgaggggc agcccgaaag gcggatgcag gcgtgatcgc cggtgcagac gtcttcatcg
       61 acgccgaagc gctggcgcac catgcgctcg cccgccttca ccgccttggc gaacagcggc
      121 cgctcgcggc gctggcgatt cagcatgcac tccgacgacg ccacgatcac tttcggcccg
      181 gcctgctcgg tggtcagcgc ctccttcaag gtgtcgcgca cgcgggcgac atcgtaggtg
      241 cggtcgatct ggcgtaccca gtcgacgccc atgcccttga cggcctcggt gatggcatgc
      301 cgcgtcgacc gcgagcggtt ggcggcgcgc gacgacagca ggtcctggcc gccggttgcc
      361 gccgaatagt ggttgtcgac gatcagcacc acgccgtcgc tcttgttgaa cacggcgttg
      421 ccgatgcccg aggtcagccc gttgtgccag aagccgccat cgcccatcac ggcgatggag
      481 cgcttgcctg ccttgacgtt gaacgccgag gccgaggctg gtcccaggcc gtagcccatg
      541 gtggtcgtgc cgatgttgaa cggcggcata atcgcgaaca gatggcagcc gatgtcggcc
      601 gcgacgtggt gcgggcccag ctcgcgctcg accagcttca tggcggcgaa gatcggccgt
      661 tcgggacagc cggtgcagaa gccgggcgga cgcggcggca caacctcggc caacgcacgg
      721 gcatgcttct cttccagggc cggcggcgca ttggaggcgc gcacggacgg cgccagcaca
      781 tcggggatcc actgccgcac gaaggcgccg accgcatcgc ccatgacctg ggcggtgtat
      841 tcgcccgcca tggggaagac gtccttgccc gagagcggcg tgccgatgcc cgcctggcgc
      901 aggatcttgg acagcgcctg ctcgatgaag tcgggttgcc cctcttccac cagcagcacc
      961 gcgcgcttgt tgcggcagaa gtcggcgacc tcgtccggca ccagggggta ggtgacgttc
     1021 aggacataga gcggaacgcg gctggtgccc cagacatcgg ccaggcccag gccctgcagg
     1081 gcgcgcagca cgccgttgta catgccaccc tgcaggatga tgccgacgtc gccgatgtcg
     1141 cccggcacga actcgttcag gccgcgctcc ttgatgaact tcaccgcggc aggccagcgt
     1201 ttctcgatct tctccttctc atggaggtag gaggctggcg gcaggacgac gcggccggta
     1261 tcgcgccgcg gcgcctcgag cgcgtccttc acgctcatcg tcggccgctg gttggccttg
     1321 gtgcggaagc tgccgcgcac gtgacaggcg cggatgcgca cttccagcat gaccggcgtg
     1381 ttcgacgcct ccgaaagctc gaagcccagc tccaccgagc gcacgatgct ttccaggttg
     1441 ggccgcggat cgagcagcca gacctgcgat ttcatggcgt aggcgtggct gcgctcctgc
     1501 atgatcgagg agccttcgcc gtaatcctcg ccgacgatga tcagagcgcc gcccgtgacg
     1561 ccgcccgacg ccagatttgc aagcgcatcc gaggcaacgt tcgtgccgac cggcgacttg
     1621 aaggtgacgg cgccgcggat gggatacatg accgaggccg cgagggtcgc tgccgccgtc
     1681 gcttcgctgg cgctcgattc gaagtgaacg ccgaggtcgc tgaggatgtc ctgcgcatcg
     1741 gacagcacgt ccatcagatg cgagatcggc gcgccctgat agcctgcaac atagcccacg
     1801 cccgattgca gcagggcctt ggtgatggcg aggatgcctt cgccatggaa ctcctgcccg
     1861 tcaccgagcc ttaggtcctc tacctctttc gcgaaggatc gttcagccat cgggcgtccc
     1921 tcatcgcaat ggagatattt aaggagtgaa gcttttatct gtcaatcgat cgcggtgtgg
     1981 ccttgacgat cgttttcgag aaactttagg attgaaacat ctcggcttgg ggggacgggc
     2041 tttcaatggc tcgacagaaa ctggtcgatc gcagccgcga aggcgtgcgg catatggtcg
     2101 ggaagcggca cggtgccggc ttcgatctcg atcaatttgc tgccggcgat gctggcggcg
     2161 acggcgggcg cgtgcgggtg ggcatgcggg tcggccatgg gcgcgatcac cagagtcggg
     2221 cagcgcacca acggcaggcg cggttccatc acatagcggc cgacgacgcg atggccttcg
     2281 gcggcgcgcg gccccgcctt cagcgcatcg acgatgaagc gttccagaag atcgccacgg
     2341 ccttccggat agaagggctg gcgtctcgcc cacagttcct ggagatgccg gccgtcgtga
     2401 tgcgcggcga cctcgtcgat cacgcgcttg ccgggctccc tcgcccgccg cgccgcatcg
     2461 acataagggc aggccgacag caccagcgcc tcgacccgct cgggctgcga cgccgccatc
     2521 tcaacggcga cagccgcccc ggtatgatgg cccgcgatga cggcgcgggc gtggcccagc
     2581 gctgccagga cttcgtgcgc cgcagccgcc caggcttcga tggaatcgct gccgtccggc
     2641 agaggctcgg aatcgccgaa accgacggta tccatggcga tggcacggta gcgtgcgccc
     2701 aggagcggca gcacctcgcg atactcgtcc caggagcgcg gcgtctggtg cagcagcagg
     2761 atcggccgtc cggcgccgca ggccgcgaca tgcacaagtc cggatttgat acgcacgaaa
     2821 gagcgttcga tcatgtcact acggggataa gggctgaaaa aggagacaat gatgaagaat
     2881 agcatcgcgg cggccgtcgt cgccgcctct cttgggtttg ccacggcggc gcaggccgag
     2941 atcacggtcg gattcatcac ctcgcagagc gggccgggct cgtcgatcgg ggtgctctac
     3001 gaccgcggca tgaaggcggc cgtcgagtac gcgagcagcg tgggcgctga gaaggtcaag
     3061 ctgatccagc tcgacgacgg ctccgatccg tcgtcggcga cgcgtaacgc gcgcaagctc
     3121 gtcgaggaga acaaggtcga cctgctgatc ggcacatcca cggccgcctc gaccagcgcg
     3181 atggtgccga tcgccaacga gctgaaagtg ccgatgatcg cgatctcgcc catcagcgtg
     3241 gcggcgaacg acgccggcga ccgctgggcg atcgtcatgc cgcagccgcc caccctcatg
     3301 gtgaaggtgg tggtcgaccg catgaagcgc gatggcgtga agcagttcgc ctatatcggc
     3361 ttctccgacg cctggggcga cctcgtctac aacggtgcgc agaagcccgc cgaggcggat
     3421 gggctgaaga tcctgaccaa cgagcgctat gtgcgcaccg acacctcggt gacgggccag
     3481 gtgctgaaga tgatggcgac caagcccgac gccgtgctgc tgggcggtgc cgcgacccaa
     3541 ggcgctctgc cgccgctagc gctggccgag cgcggctaca aggggccgct ctatggcacg
     3601 ccggcattgc tcaataccga cttcatccgc gtcggcggca aggcagtcga gggcgtgcag
     3661 gtctcggccg gtccagtggt cgtcgccgag cagctgcccg acacgcactt cagcaagaag
     3721 atctccatgg acttccgggc cgcctaccag aaggcgaacg gctcgccgac atcggacgcc
     3781 ttttcggcct actccttcga tgcctggctg gtgttcctcg acgccgccaa gcgggcgatg
     3841 gccacgggcg ccaagcccgg cacaccagag ttccgcgtgg cactcaggaa cgcgatcttc
     3901 aacaccaatg acctcgtggg cacgcacgcc atctacaact acaagcccag cgacagctac
     3961 ggcgtcgacg agcgcgcgct ggtgatggtg cggctggtca acggccagtg gaagtacgag
     4021 ccctgagccg atggccctaa gacgatgaac ggcgagatcg cggcaatcct ggcgatggac
     4081 ggcatcgcca gcggggccat ctatgtcctg attggcctcg gcctagtgct gatcttcgcc
     4141 gtgacgcgcg tgatcttcgt gccgttcggc gatatcgcgg ccttcaccgc gctcagtctc
     4201 gcctcgttgg aaacaggagg ccgaccgggc acggtcggcc tggtggcggt gctcgcggtg
     4261 ctggcgacgg cggtcgaggc ggtcgccctc gtcaggaacc gcgcgttcca tcgattgccg
     4321 cgcgccctgc tgttttatct ggtcctgccg ctgataccgg ccgcggcggt ctggttcgcg
     4381 gccggcacga cgttctcgat gccggtcagg atcgtgctgt cgctggccct cgttctgccg
     4441 atcgccccgt tgctcgatcg catcgtgttc cggccgatcg ccgatgcctc ggtcctgctg
     4501 ctgctcaccg tcgcggtggc tttgcatttt gcgctgagcg ggctcggcct gatgttcttc
     4561 ggcccggaag gcgtgcgtac caagccgctg accgacgctg tgttcgacgt cgcgggcctc
     4621 atcgtcaacg gccagatgct gctgatcctg gccgcctcga tcgtgttctg cggcctgctg
     4681 ttcctctatt tcgagttcac cattcagggc aaggcattgc gcgccacggc ggtcaaccgc
     4741 gtcggcgcgc gcctggtcgg catccggccg acctcgaccg gcacgatcgc ctacctgctg
     4801 gcgtcgctgc tcgccggcat ctcgggcgtg ctgatcgcgc cggtgacgac gatcttctac
     4861 gattcgggct tcctgctcgg gctgaaggcc ttcgtcggcg ccatcatcgg cgccatggtg
     4921 agctatcccg ttacggcgct gggcgctgtc atggtcggcc tgctggaaag cttcacctcg
     4981 ttctggctga gcgcctacaa ggaggtgctg gtcttcagcc tgctcattcc cgtgctgctg
     5041 tggcgctcgc tcgccttcgc cggcaccgag gaggaagagg ccgaggaatg acgcgcctgc
     5101 aattccacct cgttgcggcc gccggagttc tgctgctggc gctcgcaccg gcgctgctca
     5161 gcccgttcag catcacgctc atgaacttca tcggcatcta tgcgctggcc gtgctcggcc
     5221 tggtgctgct gtcgggcatc ggcggcatgc tgtcgttcgg ccaggctgcg ttcgtcggca
     5281 ttgccgccta cgccactgcc tggctcaccg tgaaggcggg ctattcgccg tggatcgggc
     5341 tggtcgtagg cgtcgtgctc accgggctgg ttgccgccat cctcggcgcc gtgaccctgc
     5401 ggctgggcgg ccacttcctg tcgctcagca ccatcgcctg ggggctggcg acctacttcc
     5461 tgttcggcaa cgtgcccatg ctgggccagt acaacggcat cagcgaaatc ccgccgatct
     5521 ccattggcgg ctacgcgctc tccagcagca acagcatcta ctacctgatc tgggttttcg
     5581 tgatcgtgtc cctggtgctg tcggccaacc tgctcgattc gcgcgagggc cgggcggtac
     5641 gcgccctgcg cggcggccag gtcatgaccg agagcctggg catcaatccg ttccgggtga
     5701 aactcatcac cttcgtgatt gcggccctgc tgtcggccct gtcgggctgg ctctacgccc
     5761 atatgagccg cttcgtcagc cccgcgccct tcgacgtcag cgtcggcatc ctctacctgc
     5821 tgatggcgat ggtcggcggc atggcctacc tctcgggggc gatcgtgggg gcggccgtcg
     5881 tcaccctgct caagaacagc atccaggact ggctgccggt gatctcgccg ggtgcctcgg
     5941 gacagctcga agtcatcgtg ttctcggtgc tgttcatcct ggtgctgcag cgggcgcggg
     6001 ccggcatcgt gcccctcgcg ctgcgctggc tgccgcgcgt gcagcctacc ccgcccctcg
     6061 cttcgggctc gctcgtgcat cgccagcaac ccgagcgcgg ccaaccgatc ctgaccatcg
     6121 ccggtgcgac ccgccgcttc ggcggccttt tagccgtcga caatgtgagc ttcgaggtca
     6181 aggccggcga gattctaggg ctgatcggcc ccaacggtgc cggcaagacc accatgttca
     6241 acctgatcac cggcgcgctg ccgctgaacc agggtcggat cagcttttta gggcaggaca
     6301 tcagccgcca cgcccagcgc cagatcgccc gcgccggcat cgcccgcacc ttccagcacg
     6361 tgaagctgcg caagaccatg accttgctcg acaccgtgct gctcgggacc tacggccgca
     6421 ccagttccgg cttcttcgcc ggggtattgc gcctcgaccg cgccgaggaa gcgcgggccc
     6481 aggctgaggc gatgcggcag ttgcaacgtg tcggcctggc cgaccgcgcc ttcgagctgg
     6541 ccggcaacct gccgctcggc aaccagcgcc tgctcgaaat agcccgtgcg ctggcggccg
     6601 atcccgcact gctggtgcta gacgaacccg ccgccggcct gcgttcagcc gagaaagccg
     6661 agctcgccca tctcctcgaa gcgctgcggg ccgagggcct ctccatcctg ctggtcgaac
     6721 acgacatgga tttcgtcatg ggcttggtcg accgcacggt ggtgatggat ttcggcgcca
     6781 agctctgcga gggcacgccc gccgtcgtgc gcagcgaccc gcgcgtccag gaagcctatc
     6841 tcggcggggt ggcgtgagat ggcgctgcta tcgatcgacc aggtctccgt cgcctacgac
     6901 aaggtcgagg cggtgcgcgg cgtttcgctc gccatcgagc ccggccagat cgtcaccgtc
     6961 atcggcccca acggcgccgg caagaccacg ctgctgggtg ccgcgatcgg cctgctgccg
     7021 tggcgcggcc gcatgtcgtt cgatgggatc gacctgcgac ggctcgatgt cgaggcgcgc
     7081 atcgagcgcg gcttctgcct ggtgcccgag acgcgcgagc tgttcggcga tctctcggtg
     7141 tcggataatc ttttactcgg cggctattca cgacgacgcg attcggcagg gctgaaacag
     7201 tcgctggccg acgtctacaa gcgcttcccg cgcctggacg aacggcgcaa ccagaaagcc
     7261 tcgaccctgt ccggcggcga gcgccagatg ctggcgctgg gccgcgccct gatggccaag
     7321 ccgcgcctac tgatgctcga tgagccgagc ctcggcctcg ccccgatcat cgtccgcgag
     7381 gtcttcaaaa tcatcgcctc cctgcgcgag ctcggcgtgt cgatcctgct ggtcgagcag
     7441 aatgcccgcg ccgccttgga aacggccgat ttcggctatg tgctggagac tggcgagatc
     7501 gtccattctg gcgccgccgc cgacctgatg cacgacccgc gcgtcaccgc gagctacctg
     7561 ggcgggcact agatatttta gatatgaagc tttatactta aagggtatat cgtcatcttg
     7621 ccggaccgcg ggcctccagg cccgctcatg atcaagacta tgagcgggcc tggagacccg
     7681 cggtccggca agacagaagg agagctgagg tgaaggttgc tgttctcggc gccggccccg
     7741 ccggcctcta cttcgccatc tcgatgaagc gccgcaaccc cgggcacgag atcacggtgt
     7801 tcgagcgcaa caagccagac gacacgttcg gctggggcgt cgtgctctcg gccgagacgc
     7861 tcgacaacct cgcggccaac gacgcggtca gcgccgcctg gatccgggaa tacttcgcct
     7921 actgggacga catcgctgtg atccacaagg gcgtgcgcac cgtctctacg ggccacggct
     7981 tctgcggcat cggccgcaag cggctgctcc tgctgctgca gcggcgcgcc ggcgatctcg
     8041 gaatcgagct caagttcgaa acggagatcg acgatccgcg gccgttcatg gaaagccacg
     8101 acctggtgat cgccgccgac ggtctgaatt cgcgctcgcg cgcggccttc gccgaggtct
     8161 tcaagcccga catcgacgtc cgcaagtgca agttcgtctg gctcggcacc cgccagaagt
     8221 tcgacgacgc cttcaccttc atcttcgagg agaccgagca cggctgggtg tgggcgcacg
     8281 cctaccaatt cgagcccgag accgcgactt tcatcgtcga atgcagcgag gagacctggg
     8341 ccgcctgggg ttttagcgac atgacgcgca agcagtcgat cgcggcctgc gaacggatct
     8401 tcgccaagca tctcggtggc cagagtttga tatccaacgc cagccacctg cgcggctcgg
     8461 cctggatcaa tttcccgcgc gtgctctgcg agcgctggtc gcacaagaac ctcgctttgc
     8521 tgggcgacgc ctcggccagc gcgcatttct cgatcggctc gggcaccaag ctggcgctcg
     8581 agagcgcggt ggcgctcgcc gactatctgc attccgagcc cggtctcacg gcggcgttcg
     8641 agaagtacga aagcgcgcgc cggaccgagg tgctgcgcct gcagtcggcg gcgcgcaatt
     8701 cgctggaatg gttcgaggag gtcgagcgct acctcgacct cgaccccgtg cagttcaact
     8761 actcgctgct aacccgctcg cagcgcatca gccacgagaa cctgcggatg cgcgatccgg
     8821 cgtggctggg cggcgccgaa gcctggttcc agcgccgcgc cggcaacacc gacaatctgc
     8881 gtcgcgcccc aatgttcgcg ccattccagc tgcgcgacct gaaactcgcg aaccgcgtcg
     8941 tcgtctcgcc catggcgcag tacaaggcgg tcgacggctg cccaaccgac tggcacttcg
     9001 cccactacgc cgagcgcgcc aagggcggtg caggcctgat ctatatcgag atgacctgcg
     9061 tcagccccga aggccgcatc acgccgggct gcacggggtt ttatgcgccc gagcacgagg
     9121 tcgcctggaa gcgcctggtc gatttcgtgc atgccgagac cgaggccaag atctgcgccc
     9181 agatcggcca ctccggcgcc aagggatcga cccagctcgg ctggcagcag atcgacgcgc
     9241 cgcttaaaag cggcaactgg ccgctgatgg ccgcgtcgga agttccgtgg tcgccggaaa
     9301 accaggtgcc caaggcgatg gaccgcgccg atatggcgcg catcagggag cagttcgtgg
     9361 cctcggcgga gatggccgcg cgctgcggct tcgacatgct cgagatccat gccgcgcacg
     9421 gctatctgct gtcgtccttc atcacgccga tcaccaacca tcgcaccgac gaatatggag
     9481 gtgcgctgga gaaccggctg cgctatccgc tggaggtctt ccaggccgtg cgtgcggtct
     9541 ggccggcaca taagccgatc tcggtgcgca tctcggccaa cgactggatg ggcgatgagg
     9601 gcgtgacgcc ggccgaggcc gtcgagatcg cgcggctgct gcaggcggcc ggcgtcgaca
     9661 tctgcgacgt atcggccggc cagacctcga tccgcggccg cccggtctac ggccgcatgt
     9721 tccagacgcc gttctccgat cgcatccgca acgagaccgg catggccacc atggcggtcg
     9781 gcaacatcta cgagcccgac cacgtcaact cgatcctgct ggccggccgc gccgatcttg
     9841 tatgcctggc gcggccgcac ctcgccgatc cctactggac cctgcatgcc gcggtgcagc
     9901 tcggtgaccg cgacgtgaag tggcccgatc cttatctcaa cggccgcgat cagctctatc
     9961 ggctggccga ccgcggcggt gcgaccatgg ggccgaaagt atgatctcag gcaaacatgc
    10021 gctggtgacc ggcggcggca cgggcgtcgg acgggcggtc gccctggcgc tcgctaaagc
    10081 gggcgtctcc gtcaccatct gcggccgccg caaggccaag ctcgaggcgg tggctggcga
    10141 gaacgcccgg atcttcccga tcgcggccga cgtcactgac gaagccgcaa tgacggctct
    10201 ctatgccgag gccgaggaac tgcgcgggcc gttcgacatc gtcgtagcca atgccggcgg
    10261 ggccgaaagc agcccggcgc acaagacgtc gctcgccgac tggcagcgtg cgctcgatct
    10321 caatctgacg ggatcgttcc tgaccgtgaa gcccgcgctc ggcggcatga ccaagcgcaa
    10381 ggcgggccga atcgtcttcg tcgcctcgac ggcgggactg aagggctacg cctatgtggc
    10441 accttatgtt gccgccaagc acggcgtcgt cggcttgatg cgggcgctgg caaccgagac
    10501 ggtgaaatcg ggcgtgaccg tcaacgcagt gtgcccgggc ttcatcgaga ccgacatgct
    10561 ggaggagtcc gtgcagcgca tcgtgcgcac gaccggccgc accgtcgagc aggcgcggac
    10621 cagcctcgcc agcaccaatc cgcagggccg cttcatccag cccaaagagg tcgcggcggc
    10681 agtgctgtgg ctctgcagcg aggcggcggg ttcggtgacc ggtcaggcgc tgtcgctgtc
    10741 gggaggcgag acgtggtgag tggaccggtc tctgcttcca aggagaagct caggctctgg
    10801 atccggctgc tgcgcgcctc gcgcaccata gagggcgagc tgcgcgagcg gctgagcacc
    10861 gagttcgaca ccaccctgcc gcgtttcgat gtcatggccg ccctctatcg cgtgcccgac
    10921 ggcatgctga tgagcgacct gtcgcgcttc ctgctggtct ccaacggcaa cgttaccggc
    10981 atcgtcgacc gtctggtgtc cgaaggcctg gtgcagcgcg gccagcgcaa cggcgatcgc
    11041 cgcacctcga tcgtgcagct cacgaaggcc ggcaaggaca cctttcgcac catggcggcc
    11101 gcgcacgagc gctgggttgg cgaattgctg gccggcgtca ccaagagcga cgccaagcag
    11161 ctcacgtcga tgctgaaggc ctttcgcagc aattgggagg gacgggaatg accaagatgg
    11221 cgggcttccg gcccaagcac ttcctctggc aggtcgaagg caaggtggcg catatccagc
    11281 tcgaccggcc ggagcgcaag aatccgctca ccttcgactc ctacgccgag ctgcgcgata
    11341 ccttccgcga gctgcgctac gctgaggacg tcgacgtggt ggtgttcctg cccaacggcg
    11401 gcaatttctg ctcgggcggc gacgtgcgcg acatcatcgg gcctctggtt gccatggaga
    11461 tgaaggagct gctcaacttc acgcgcatga ccggcgatct cgtcaaggcg atgctcgctt
    11521 gcggcaagcc gatcatcacc gccgtcgacg gcgtcgccgt gggcgccggc gccatcatcg
    11581 tcatggcctc cgatatccgc atcgccacgc ctgaggccaa gaccgccttc ctgttcacac
    11641 gcgtgggact cgcgggctgc gacatgggcg cctgtgcgat cctgccccga atcatcggtc
    11701 agggccgcgc cgccgagctt ctttataccg gccgcagcat gtcggcggcc gaaggcgagc
    11761 gctggggttt ctataatcgc ctggtcgacg ctggggcact ggaacccgac gcgctcgaca
    11821 tggcccggcg catcgcctcg ggcccgacct tcgcgcacgg catcaccaag acccagctga
    11881 accaggaatg gtcgatgggc ctcgaccagg cgatcgaggc ggaggcccag gcgcaggcca
    11941 tctgcatgca gacccgcgat ttcgagcgcg cctaccgggc cttcgtcgcc aagcagacgc
    12001 cggtgttcga agggacctga agatgctggg accgagcgca catatcgaca ccttcagccg
    12061 cgacaatctt ccgcctgcgg cgcagctgcc ggacttccgt ctggccggct tcgactatcc
    12121 cgagcgcctg aatgtcgccg tcgaactgac cgaccgcatg gtccagaagg gctttggcga
    12181 caataccgcg ctgatcggca atggccgccg ccgcacctac aaggagctga ccgactggac
    12241 caaccgactg gcgcgcgccc tggtcgagaa ttacggcgtg cggccgggca atcgcgtgct
    12301 ggtccgcgcc gccaacaacc cggccatggt cgcctgctgg ctggcggcca ccaaggccgg
    12361 cgccgtcgtg gtcaacacca tgcccatgct gcgggccggc gagctggcgc agatcgtcga
    12421 caaggccaag atcgcgctgg cgctctgcga cacgcgcctg atggacgagc tggtggcctg
    12481 cgccaaggac agccgcttcc tcgagcaggt cgtgggcttc gacggcacgg ccaaccacga
    12541 cgccgagctc gaccgtgtcg cgctgaccaa gccggtgcgc ttcgaggccg tcgccaccgg
    12601 tcgcgatgac gtcgccctgc tgggcttcac ctcgggcacg accggggtgc ccaaggccac
    12661 catgcacttc catcgtgacc tgctgatcat cgccgacggc tacgccaagg acgtgctggg
    12721 ggtgacgccg gacgacgtgt tcgtcggatc gccgccgctt gccttcacct tcggcctggg
    12781 tgggcttgcg atcttccccc tgcgcttcgg cgcggcggca acgctgctcg agaacgcctc
    12841 gcccgcgaac atggtcgaga tcatcgagac ctaccgcgcc accatcagct tcacggcgcc
    12901 cacggcctac cgcgccatgc tgacggcgat ggatgctggc gccgatctct cgtcgctgcg
    12961 cattgccgtc tcggccggcg agaccctgcc cgcgccggtg ttcaacgact ggctggccaa
    13021 gaccggcaag ccgatcctgg acggcatcgg cgccacggag atgctgcaca tcttcatctc
    13081 caaccgcctc gacgacctcg ctcccggctc gaccggcaag ccggtccgcg gctacgaggc
    13141 ccgggtcgtc gacgaggcca tgaaggaggt gccgcgcggc acggtggggc ggctcgccgt
    13201 gcgcggcccg accggctgcc gctatctcgc cgacgagcgc cagcgcaatt acgtgcgcga
    13261 cggctggaac ctcaccggcg attccttcgt gcaggacgag gcgggctatt tccacttcgc
    13321 cgcgcggtcg gacgacatga tcatctccgc cggctacaac atcgccggcc ccgaggtcga
    13381 ggcggcgctg ctgacccatg ccgacgtggc tgaatgcgcc gtgatcggca ttgccgacgc
    13441 cgagcgcggc cagatcgtcc aggcgcatgt cgtgctggcc gacggcgtcg cgccggacct
    13501 cgacaccaca aaacgcctgc aggatcacgt caaggcgacg atcgcgccct acaagtatcc
    13561 gcgctcggtg aagttcacgc ctgccctgcc gaagacccag acgggcaaga tccagcgctt
    13621 tctgttgaag aaccaaggtt gatcatgaca acgcacacga tcctgcagcc ggccggctgg
    13681 gcgaaaccca acggctacgc caacggagtc gccgcccaag gccgcttcgt gttcgtcggc
    13741 gggcagatcg gctggaacgg ccagagccgc ttcgagacag acgacctcgt gggccaggtc
    13801 cgccagaccc tgcagaacgt cgtcgacgtg ctggccgagg ccggcgcgaa gcccgagcac
    13861 gtcacgacga tgacgtggta tctcacgaat aagaaggact acctcggcaa cctcgcgggc
    13921 atcggcaagg cctatcgcga gatcatgggg cgcaatttcc cggcgatggc cgtggtcgag
    13981 gtcacggccc tggtcgagga ccgcgccaag gtcgagatcc aggctatggc ggtcgtgccg
    14041 atgtgaccat cgtctgcgac ggacacgtca cgcaagctcc tctcccccgc tagggggaga
    14101 ggttggatga gggggttaca
//
