LOCUS       c00188_NZ_BKAJ..       19720 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BKAJ01000188.1 Reyranella soli strain NBRC 108950 sequence188,
            whole genome shotgun sequence.
ACCESSION   NZ_BKAJ01000188
VERSION     NZ_BKAJ01000188
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:01:08
            Original ID  :: NZ_BKAJ01000188.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19720
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19720
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7142:16262]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7143..16262
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..19720
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="chemical_hybrid"
                     /product="TPP_AA_metabolism"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..19720
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(7..756)
                     /locus_tag="ctg188_1"
                     /transl_table=11
                     /translation="VAADEVFEDSLFASLYDHFNGWDICDDFYFDLARTLKSGARVLDL
                     GCGTGLLACRIAEHGFAVTGVDPAEGMLDVARARPGAERVSWIKSAGQTMRLSQCFDLI
                     YMTGHAFQALLADEDAVAVLRTARDHLADDGLLAFETRNPARKAWLSWTPDRRRSAVTA
                     DHGEVEEFFEAKADPDSGIVNLAAHYRFVRTGKTMVGRSRIRFIDLDHLKRLLVAAELA
                     PMTWYGDWDRSPLTETSREFIVLARPS"
     CDS             complement(756..1898)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 55.1; E-value: 2.3e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg188_2"
                     /sec_met_domain="FeS_assembly_P (E-value: 7.3e-18,
                     bitscore: 55.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="CbiA (E-value: 1.3e-15, bitscore: 48.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEITESAVRKVLETVIDPATAKSVVAQGMVGGIAVRGGHVAVTL
                     DVDPARGTALEPLRQACEQAVRAMPGVLSATAVMTSERPAPSAAPATHAHGHGHAAPGG
                     KTTGGGGRIDVPGVKHIIAVASGKGGVGKSTTAVNLALGLAANGVATGLLDADIYGPSM
                     PRMLNVKDKPESVDGKALKPIERYGLKTMSIGYIVNEDTPMIWRGPMVSSALEQMLRDV
                     QWGELDVLVVDMPPGTGDAQLTLAQRVALAGAVIVSTPQDIALVDARKGLNMFRKVAVP
                     VLGFVENMSFYLCPHCGERAEIFGHGGAREEAEKLGVPFLGEVPLHLDIRTTSDSGHPI
                     VVSQPDSQYAQIYKNIAGRVWKQLTANQRGPRAAPRIVVR"
     protocluster    1008..19720
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11007:17924]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      11008..17924
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="2"
     CDS             2038..3240
                     /locus_tag="ctg188_3"
                     /transl_table=11
                     /translation="MAWNNNSGGPWGGGGGGGGNGGGPWGGGGGNRGGGGGPFGSRRPP
                     DMEDVIRKGQERLKNLIPGGFGTYKGIVLVVLLGVVIWLVTGFFRVQPNQQAIQLVFGK
                     PYGKPVEPGLHYNLPSPIGNVVVVNVQDQRRVVIGSRGGQDRSTTYTRGGPRPTSTENL
                     MLTGDENIVDIEFAVLWQIKDVFKYAFDVRNPEENVRAGAEAAMREVIGRSNLQYAQTE
                     GRSRIEQDAKDLLQRILDEYGLGVRISNVQLLRVDPPQEVIAAFRDVQAARADKEKSIN
                     EANTYRNQVLPRAKGEAESIIQRGEAYKAEVIARASGDAQRFDQVYEQWAKAKDITTER
                     LYLDTMEEVLRNVNKVMIDKNSAGGAGGVIPYLPLPELKSGQPAPSAAPRTAPPAPGAT
                     R"
     CDS             3237..4124
                     /locus_tag="ctg188_4"
                     /transl_table=11
                     /translation="MSNRAIVALIAIAVAIFLVTQTFYTVDPTKQVLVRQFGAIVGDPK
                     TEPGLYAKLPLIQDIQRIDRRLLDYEAEEFEIIAGDQKRLVVDAYARYKITNAKTFAQT
                     VPGGEPALRGLLDSLINSEIRGVLSSVPLHAVLTDRRESLMDDITKRVNAKTRDLGVDT
                     VDVRIKRADLPQANSQSVYNRMKTDREREAGQLRAEGDEEKARITATADREVAVIKADA
                     GLKAQVLKGEADAEATKIYALAFNKDKDFYAFYRRMEAYKQAFGAGGSTMILSPDTDFF
                     RYFNDPSGLPAAKK"
     CDS             4344..5837
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trypsin_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1057:Trypsin-like peptidase (Score: 119.1; E-value:
                     1e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg188_5"
                     /sec_met_domain="Trypsin_2 (E-value: 3.2e-37, bitscore:
                     119.1, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VILTDFPGVLRSAAVVAAVSLGLALAQPAVAQPARNAPDSFAELV
                     DKLMPTVVNITTTQNVPQQGPRLRDMPQLPPGSPFEELFKEFFDKRGGEEQKRRGTSLG
                     SGFVIDPDGYIITNNHVIQGAEDITVIFRDDTQLKAKLIGSDSRIDVALLKVEPPSKKP
                     MAAIKWGDSDKERVGDWVIAIGNPFGLGHSVTAGIISARGRSLNDSLDDYLQTDAAINK
                     GNSGGPLFNAQGEVIGVNTAIYSPSGVNAGLAFSIPSNLVKQVADQLREFGRVKRGWVG
                     VSYQSVTDDIADSFGLDRARGVLVANVVADGPAAKAGLKRNDIILSFSGQDVLDLRRFP
                     RLVANARVGSTVDVVVWRGGKEVPLKLRIGEQEDEGKTNAAAKGGDKKPAEPDQPVVST
                     VEQLGLTLQKVTDQLREKYGLSDQVKGVVITKVTPNSPAAEKQLQAGDVILEVDQKPVT
                     TPQEVTDLVGKLQQAKKRSVLLFVERQGDPRFAALRLTK"
     CDS             complement(6010..7146)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg188_6"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.3e-21, bitscore:
                     67.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGITALTGARIFDGDRWHDGAAVLIRDGAIMGIASQSDLPADAA
                     VQRIDGGMLVPGFIDAQVNGGGGVLLNDTPTAAAMDAIAAAHRTFGTCRLLPTLVTTST
                     ETTRAALAAVRHAGPGVAGLHLEGPHLAPARKGVHDPRFMRRMTDADVEMLLSADIGRL
                     VVTVAPEQVEPAQVRRLVDGGVIVSLGHSDATYEQAMALFDAGATGVTHLFNAMSPLQG
                     RAAGLVGAGLDAGAVWCGIIADGLHVAPSALSIALRAKRAPGRLFLVTDAMPTVGSAAT
                     SFRLGERTIDRRGDRLTWTDPSGAEVLAGAHLDMATAVRFCVDVLKLPLEEALRMAALY
                     PAKFLRLDDKHGRLVRGHVADIVHLGADLTVRRTWIGS"
     CDS             complement(7143..8012)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_7"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.2e-33, bitscore:
                     107.1, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNELFLGIDAGGTHCRARLVDADGNVLGSGRGGPANLTWGIDKAH
                     RAIMAASAEAFAEAGLGRAAMRRTHAGMGIAGADDPAQARKMAARRFGFASVTIRGDAE
                     TACIGAHEGRDGGVLILGTGSNGLVRRRGKLERVSGDGFLISDLGSGAVVGHAAARQAL
                     AAHQRVIAPSPLTRRIMRRFDNDPSKMRAWAMAATPSHWGELAPLVFACSDKADPVARR
                     LVADAVADVTRLLDRMIALGAKRIALTGGLADAYASRLPRRLARILVPAQRDALSGAID
                     LARKMVGT"
     CDS             complement(8038..9042)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg188_8"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.6e-21, bitscore:
                     66.4, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAVQIVLAKRPAGDVTADCFREEKVTLPVLADGEVLVRSRFLS
                     LDPYMRPRMTELRSYTPPFELGKPLTGGSVGEVVDSKNPRFAKGDTVIGMLNWASHTLH
                     DGKGLRKIDPALAPLSAHLGVLGMPSFTAWYGIRHICKPKAGETVFVSAATGAVGQVAG
                     QLAKLAGARVVGCAGGEDKCAWAVREAGYDACFNHKTEHDVGAVLDKLCPQGIDADFEN
                     VGGRIFHAVFERLNNFGRVAFCGAISEYQDQTPMAGPPKMFTIVQRRLTLQGFIVSDHI
                     ALMADFVNEVGGLVKEGKLKSRETVVDGLAGAPAAFMGLLKGENFGKLVVRIA"
     CDS             complement(9039..9920)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg188_9"
                     /sec_met_domain="HAD (E-value: 5e-19, bitscore: 59.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNVLVLISSAAHPALNDGAIRNAVAVLQAQGASVGTPQWLAPEI
                     ACDIPFDGEARPVAMAAIDAVVVPSAGRRKKLLVADMESTMIENEMLDELADFLGLREK
                     IAGITARAMNGEIDFAGALNERVALLKGLDVAKLDEAAKRIRYMPGGATLVATMKKHDG
                     HCALVSGGFTHFTALVHKALGFDSHAANGLQHDGRTLAGTVDLPILGKEAKLATLQRLA
                     AERGFSPADAVTVGDGANDLPMLKAAGLGVAFHAKPAVAAEVAARIDHGDLTALLYLQG
                     YRRTEFVERTDP"
     misc_feature    complement(9624..9626)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             9970..10896
                     /locus_tag="ctg188_10"
                     /transl_table=11
                     /translation="MAQQQVLVITGPTASGKSALALAVAAGHGGTVINADAMQTYDAFP
                     ILTAQPTAEERQSVPHALYGVLPLSETLSAARWRDLASAEIERCLTAGRMPVLCGGSGL
                     YLRTLMHGIAAIPDAPDGLRDQANAEWKAMGAEAFRARLAEKDSAIVERLKPGDRQRHV
                     RAWEVWLATGRPLSIWQKGEGQPPPWRFATVLLAPERGWLRARIETRFDAMLKMGVLDE
                     VRAVFDQKPDARWPGLKAHGAPELFAHFRGELTLEDARRIGIDHTRQYAKRQMTWFRHQ
                     MTPDVVVDPTTDLGLEQTEKLLTKIET"
     misc_feature    10873..10875
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             11008..12777
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.3e-51, bitscore:
                     164.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPEESATTGADLLVKALIDEEVEVVFGYPGGAVLPIYDSLFKQN
                     RLRHILVRHEQAAVHAAEGYARSTGKVGVVLVTSGPGATNAVTGLTDALMDSVPIVCLT
                     GQVPTHLIGNDAFQEADTTGITRPCTKHNYLVKAVGDLARVVHEAFYVARSGRPGPVVI
                     DLPKDVLMNKHDYVAPKKPVQHKSYRPQVKPDPKKVEEAIELIAGAKRPIFYAGGGIVN
                     AGPKASKLLTQFVHMTGYPITNTLMGLGTFPASDKQFLGMLGMHGTYEANLAMYHCDVM
                     INIGARFDDRITGKLTEFSPKSKKIHVDIDPSSINKNVRVDLAVVGDAGHVLEEMIRVW
                     KARQPKVDHKALKAWWAEIDKWRERNCLAYKQDKETIKPQYALERLYHHIKDRDHYITT
                     EVGQHQMWAAQFLKFEQPNRWMTSGGLGTMGYGFPSAMGVQIAHPDALVIDVAGEASIM
                     MNIQELSTVAQYRLPVKIFILNNQYMGMVRQWQELLHGGRYSESYMESLPDFVKLAEAF
                     GAVGLRCHEPDKLDDTIQQMIAIKKPVVVDVLVDKTENCFPMIPSGAAHYDMLLGPDDR
                     AAKPVSEEGMVLV"
     CDS             12786..13286
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_12"
                     /sec_met_domain="ALS_ss_C (E-value: 1.3e-27, bitscore:
                     86.3, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIASSHTISVLVDNEPGILARVVGLFSGRGYNIESLTVAETDAKE
                     NLSRITIVTAGTPMVIEQIKAQLDRLVPVHKVRDLTVEGPHIERELALVKVKSSGDKRV
                     EALRLADVFRAKVIDAKMDSFVFEVTGNSDKVQTFIGLMEGLGLVDVGRTGIVAMSRGG
                     DAL"
     CDS             13408..14034
                     /locus_tag="ctg188_13"
                     /transl_table=11
                     /translation="VDYAVVLLGLAVVHLLAVASPGPSTVLVIQTAAIVGRRGGLLAAF
                     AMMVGALAWAAAALYGLQALFAQFEWLYVAFRIGGALFLIYLAVMIWRHAKDPLPEIAV
                     DRTAHMTGWQGFMRALLLQLSNPKIMVFFGSIFLSVLPQNTPGWMDGAVLAIVAVNEFC
                     WFALLALLFSGGPARAFYRRAKVWIDRVMGGVLAALGLRLILADR"
     misc_feature    13531..13533
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(14015..14557)
                     /locus_tag="ctg188_14"
                     /transl_table=11
                     /translation="MFRSHLFATLVISAALAACSNPDPAAPVGPAVPMPQIQGAIDNST
                     PDAAQRAMSNKTWLWTRGGGPAQIHYSSADGKDYAWVVGQSRIFAGEWQVNTVPDASGR
                     MVTQVCLRHPGSYVQGLSPTWSCRPGGTFFYEMAERESGNPLSFAGRTQALFVLQSTPA
                     NLAEVEGRVTSIIGLRE"
     CDS             complement(14590..15144)
                     /locus_tag="ctg188_15"
                     /transl_table=11
                     /translation="MTALRFPLLAAAASLSLAGCWYSSSVSGSRDGTNTMRAIDTANAT
                     TTPQQAEAFISGKTWRSTESSSGQHIHYSAPDGRDFAWFRGEERILAGEWRIETATDSK
                     GQTVTRLCLRYPGDPVHPISKTAGDQWYCRAAGSVFHWIPERVDGDVLGLAGRTQAPFA
                     LTLSNLTITQLKARANPAANR"
     CDS             15243..16262
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_16"
                     /sec_met_domain="IlvN (E-value: 1.2e-72, bitscore: 233.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 7.6e-69, bitscore: 221.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVYYDRDADVNLIKGKKVLVVGYGSQGHAHAMNLRDSGVKDVRI
                     ALKAGSATIKKAEGAGFTVMSPADGAKWADIVMVLTPDELQSDIYNADLAPNMRPGSAL
                     AFAHGLNVHFNLITPRADIDVFMIAPKGPGHTVRSEYLRGGGVPCLVAVAQNSSGNALE
                     IGLSYSSAIGGGRAGTIETTFKEECETDLFGEQVVLCGGLVELIKAGYETLVEAGYAPE
                     MAYFECLHEVKLIVDLIFEGGIANMNYSISNTAEYGEYVSGPRIVTAETKAEMKRVLAD
                     IQSGRFARDWMLENKVNQASFKAMRKRMSEHPIEEIGVKLRAMMPWIKEKALVDKTRN"
     CDS             complement(16405..17169)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: adh_short_C2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_17"
                     /sec_met_domain="adh_short_C2 (E-value: 1.2e-58, bitscore:
                     188.7, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSMTKILLITGGASGIGAETARRAAKRGYKVAVNYRSRDTQAKQ
                     IVADIEAAGGSAVALPADMANEADIVRLFAATERALGPITHLVNSAGIGYRTRVDEYDA
                     ARLANLFAINAIGLMLCCREAAKRMSTRNGGKGGAIVNVSSMASTIGGRLGSSAYAATK
                     GAVDSFTKGFAREAAAEGVRVNAVRPGMVLSEMTEKALAEPAFRARIEESIPMHRVGEG
                     HEIAETILWLLSDEASFITGAMVDAAGGGYII"
     CDS             complement(17166..17924)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: adh_short_C2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_18"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-57, bitscore:
                     184.5, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLITGGASGIGAATAKLAARRGHKVAINYRSRDAQAKKVVADI
                     TGTGGQAIALPADVSREADILSLFDAAEKALGPITHLVNSAGIGLNSRVADFDAGALER
                     LFTVNTVGLMLCCREAARRMSTKRGGEGGVVVNVSSMAGTIGGRPGAAAYAASKAAVDS
                     FTMGFAKDVALEGIRAVSLRPGMIETEMTEKTLSDRETREAIESTIAMGRVGQAEEIAN
                     AIVWLLSDEASFISGVTLDASGGGFVFGKQ"
     CDS             complement(17921..18751)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.8; E-value: 2.4e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg188_19"
                     /sec_met_domain="BPD_transp_1 (E-value: 7.7e-20, bitscore:
                     61.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTSKSSRARDRFLMHALAIVLALLALSPFLWLVLMSFKTNAEIFR
                     FPPRVLFEATWANYAALWTSDFRNSFANSLIVGVVSTVLSLLIGVPAAYALSRWTTRAG
                     GTITLWILASRMAPPIAFTIPYFLVYRHLELLDTLTGLIIIYLTFNLSLVIWMMRPFYD
                     QLPRSLEEAAWIDGATMWQGFYRIILPLSGPGLAATAILCFLFAWNDFFFALILTRTEA
                     MTAPVAVVNFMNYEGWEWGRIAAGGTMIMLPVLIFSFLVRRYLVHGLTGGALKG"
     CDS             complement(18744..19718)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 67.4; E-value: 4.5e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg188_20"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.5e-21, bitscore:
                     67.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IDVRHPLSHPLPQAGERSKNPSRERSATLGRIAKQQHRFFAFCVA
                     PSLAVLAIITLLPSLYLLATSFTPLNLTRPETLWDFSQPLESYRQLWADTRFHNSIWVQ
                     IKLSFWTVLLQLLIGLGLALLLNMRTRLLEALRTVFLIPMVLPPIVVAIIWKVIYTPDI
                     SPMHGLFRALGWNVPALITDPQWALTSIIIADTWEWFPFTMLMVLAALQMMPQELLDAA
                     KVDGASPWQLTWFITLPFVQGVLLVAGLFRLIDSIKAFPLIFILTDGGPGNLTEVTNYY
                     SYLQAFNFSYLGFSSAITVVLLAATIVLSWVIVRVVGWGARID"
ORIGIN
        1 gtaagactat gaaggacgag ccaggacgat gaactcgcgg ctcgtttcgg tcaggggcga
       61 gcggtcccag tcgccgtacc aggtcatcgg cgccaactct gccgccacca gcagtcgctt
      121 gaggtgatcg agatcgatga agcggatgcg gctgcggccg accatcgtct tgccggtgcg
      181 gacaaaccga tagtgggcgg cgaggttcac gatgccgctg tccgggtcgg ccttcgcttc
      241 gaagaactcc tcgacctctc cgtggtccgc cgtgacagcg ctcctgcgcc tgtcgggcgt
      301 ccaggacagc cacgccttgc gcgcagggtt gcgggtctcg aaagcgagca ggccatcgtc
      361 ggccaggtga tcgcgggccg ttcgcaggac ggcgacggcg tcctcgtcgg ccaacaaggc
      421 ctggaaggca tggccggtca tgtagatcag atcgaagcac tgcgacagcc gcatcgtttg
      481 ccccgcgctc ttgatccagg agacccgctc ggcgccaggc cgcgctctcg ccacgtccaa
      541 cataccttcc gccggatcga ccccggtcac agcgaagccg tgctcggcaa tccggcacgc
      601 cagcaggccc gtgccgcagc cgaggtcgag gacacgcgcg ccgctcttca gcgtgcgcgc
      661 cagatcgaaa tagaaatcgt cgcagatgtc ccagccattg aagtggtcgt agagcgaggc
      721 gaagagggaa tcctcgaaca cctcatcggc cgccactaac gcaccacgat cctcggcgcc
      781 gcgcgcgggc cacgctggtt ggcggtgagc tgcttccaca cccggccggc aatgttcttg
      841 tagatctggg cgtactggct gtcgggctgg gagacgacga tgggatggcc cgaatccgag
      901 gtcgtgcgaa tgtcgagatg caacggcacc tcgcccagga acggcacgcc gagcttctcg
      961 gcttcctcgc gcgcgccgcc atggccgaag atctcggcgc gctcgccgca atgcgggcag
     1021 agatagaagc tcatgttctc gacgaagccc agcaccggca ccgcgacttt gcggaacatg
     1081 ttgaggccct tgcgcgcatc gaccagggcg atgtcctgcg gcgtcgacac gatcacggca
     1141 ccggccaacg ccacgcgctg cgccaaggtg agctgcgcat cgcccgtgcc cggcggcatg
     1201 tcgaccacca acacgtcgag ctcgccccac tgcacatcgc gcagcatctg ctcgagcgcg
     1261 ctcgacacca tggggccgcg ccagatcatc ggcgtgtcct cgttgacgat gtagccgata
     1321 gacatggtct tgagaccgta ccgctcgatc ggcttcagcg ccttgccgtc gaccgattca
     1381 ggcttgtcct tgacgttgag catgcgcggc atcgacgggc cgtagatgtc ggcgtcgagc
     1441 aggccggtcg ccacgccatt ggcggcgagc ccgagagcca ggttcaccgc cgtcgtcgac
     1501 ttgccgacgc cgcccttgcc cgaggccacg gcgatgatgt gcttcacgcc cggcacgtcg
     1561 atgcgcccgc cgccgccagt ggtcttgccg cctggagctg catggccgtg gccatgcgcg
     1621 tgcgtcgcag gtgcagccga tggcgccggc cgctcggagg tcatcaccgc cgttgccgac
     1681 agcacgcccg gcatggcccg aacggcctgt tcgcacgcct gacgcagagg ctccagggcg
     1741 gtgccgcggg cggggtcgac atcgagggtc accgcgacat ggccgccgcg cacggcgatg
     1801 ccgcccacca tgccctgcgc cacgacgctc tttgcagtcg ccggatcgat gacggtctcg
     1861 aggaccttgc ggacggccga ttcggtgatt tcagccatgg gggctcgttt ccgtcatatc
     1921 gcaatattgt gtcgccgctt gattgcgggt gttgctgccg tcacatatat gcagcgcgac
     1981 ctgaaatcaa agccgacaat atgccgagca ggcggccttg cggccctgag gtgaaagatg
     2041 gcgtggaaca acaacagcgg cggcccctgg ggcggcggcg gtggcggcgg tggtaacggc
     2101 ggcgggcctt ggggcggcgg tggcggcaat cgcggcggcg gtggcgggcc gttcggctcg
     2161 cgccggccgc ctgacatgga agacgtcatc cgcaagggcc aggagcggct gaagaacctc
     2221 atccccggcg gcttcggtac ctacaagggc atcgtgctgg tcgtgctgtt gggcgtggtg
     2281 atctggctcg tgaccggctt cttccgcgtc cagcccaacc agcaggccat ccagctcgtg
     2341 ttcggcaagc cctacggcaa gccggtcgag cccggcctgc actacaacct gcccagcccg
     2401 atcggcaatg tcgtggtggt caacgtccag gaccagcgcc gcgtcgtcat cggctcgcgc
     2461 ggcggacagg atcgctcgac gacctatacc cgtggcggcc cgcggccgac ctcgaccgag
     2521 aacctgatgc tgaccggcga cgagaacatc gtcgacatcg agttcgccgt gttgtggcag
     2581 atcaaggacg tcttcaagta cgccttcgac gtgcgcaatc cggaggagaa cgtgcgcgcc
     2641 ggtgccgagg ccgcaatgcg cgaggtcatc ggccggtcga acctgcaata tgcccagacc
     2701 gagggccgca gccgcatcga acaggacgcc aaggacctgc tgcagcgcat cctcgacgag
     2761 tatggactgg gcgtccgcat ctccaacgtc cagctcctgc gcgtcgaccc gccacaagag
     2821 gtcatcgcgg cgttccgcga cgtgcaggcg gcgcgcgccg acaaggagaa gagcatcaac
     2881 gaggcgaaca cctatcgaaa ccaggtgctg ccgcgggcaa agggcgaagc cgaatcgatc
     2941 atccagcgcg gcgaggccta caaggccgag gtcatcgccc gggcgagcgg tgacgcccag
     3001 cgcttcgatc aggtgtacga gcagtgggcc aaggccaagg acatcacgac cgagcggctc
     3061 tacctcgaca ccatggaaga ggtactgcgc aacgtgaaca aggtcatgat cgacaagaat
     3121 tcggccggcg gcgctggcgg tgtcattccc tacctgccgc tgcctgaatt gaagtccggc
     3181 cagccggcgc catcggcggc gccacgcacc gctcctccgg ctccgggggc gacgcgatga
     3241 gcaaccgtgc gattgtcgcg ctgatcgcga tcgcggtcgc catcttcctg gtgacccaga
     3301 ccttctacac cgtcgacccg accaagcagg tgctggtgcg ccagttcggc gccattgtcg
     3361 gcgaccccaa gaccgagccc ggcctctacg ccaagctccc tctgatccag gacatccagc
     3421 gcatcgaccg ccggctgctc gactacgaag ccgaggagtt cgagatcatc gccggcgacc
     3481 agaagcgcct cgtggtcgat gcctatgccc gctacaagat cacgaacgcc aagaccttcg
     3541 cccagaccgt gccgggtggg gaaccggctc tgcgcgggtt gctcgattcg ctgatcaact
     3601 ccgagatccg cggcgtgttg agctcggtgc cgcttcacgc cgtgctgacc gaccgacgtg
     3661 aaagcctgat ggacgacatc accaagcggg tgaacgcgaa gaccagggac ttgggcgtcg
     3721 atacggtgga cgtgcgcatc aagcgtgcag atttgccgca ggccaactcc cagtcggtct
     3781 ataaccgcat gaagaccgac cgcgagcgcg aagccggtca gttgcgcgcc gagggcgacg
     3841 aggagaaggc ccgcatcacg gccacggccg accgcgaagt cgccgtcatc aaggccgatg
     3901 ccgggctgaa ggcccaggtc ctgaagggcg aagccgacgc cgaggccacg aagatctatg
     3961 ccctggcctt caacaaggat aaggattttt atgccttcta ccggcgtatg gaggcctaca
     4021 aacaagcctt cggcgccggc ggatcgacca tgatcctgag cccggacacc gacttcttcc
     4081 gctatttcaa cgatccgtcc gggctgccgg cggccaagaa gtagcgctgg aaaacgggcg
     4141 acaaaaaccg taccgacggc gttgtggcag tcctgcaacg ccgccggtcg atttttcgca
     4201 aaggccgggg aaaagccgac acaatcagca acatcaacac ctctttattt gcgccacaat
     4261 ctgccgccat gtagacagga actcgaacgc gcggcgccgg ccgttccgat ccgttgaggc
     4321 ctgagcgccg ttggaggtcg gacgtgattc tcactgattt tcctggtgtt ttgagatccg
     4381 ccgccgtcgt ggcggcagta tcgcttggct tggcattggc gcagcccgcc gtggcgcagc
     4441 cggcgcgaaa cgcgcccgac agcttcgccg aactggtgga caaattgatg ccgacggtgg
     4501 tcaacatcac caccacccag aacgtgcctc agcagggtcc ccggctgcgt gacatgccgc
     4561 agctgccgcc cggctcgccg ttcgaggaac tcttcaagga attcttcgac aagcgcggcg
     4621 gcgaggagca gaagcgccgc ggcacgtcgc tcggctccgg gttcgtgatc gatcccgacg
     4681 gctacatcat caccaacaac cacgtcatcc agggtgccga ggacatcacg gtcatcttcc
     4741 gtgacgatac ccagctcaag gccaagctga tcggctccga cagccgcatc gacgtggcgc
     4801 tgctaaaggt cgagccgccg agcaagaagc cgatggcggc catcaagtgg ggcgattccg
     4861 acaaggagcg cgtcggcgac tgggtgatcg cgatcggcaa cccgtttggc ctcggccatt
     4921 cggtgaccgc cggcatcatc tcggcgcgcg gccgctcgct gaacgattct ctggacgact
     4981 acctgcagac cgacgccgcc atcaacaagg gcaactccgg tggcccgctg ttcaacgcgc
     5041 agggcgaggt gatcggcgtc aacaccgcga tctattcgcc gtcgggcgtc aatgccggcc
     5101 tcgccttctc gatcccgtcc aacctggtga agcaggtcgc cgaccagctg cgtgagttcg
     5161 gccgcgtcaa gcgcggctgg gtgggcgtga gctaccagag cgtcaccgac gacatcgccg
     5221 acagcttcgg cctcgaccgc gcccgcggcg tgctggtcgc caacgtcgtg gccgacggcc
     5281 cggcggccaa ggcgggcctc aagcgcaacg acatcatcct gagcttctcc ggccaggacg
     5341 tgctcgacct gcgccgcttc ccgcggctgg tcgccaatgc ccgcgtcggc agcacggtcg
     5401 acgtcgtggt ctggcgcggc ggcaaggaag tgccgctgaa gctgcgcatc ggcgagcagg
     5461 aggacgaggg caagacgaac gccgcggcca agggcggcga caagaagccc gctgagcctg
     5521 accagcccgt cgtctcgacc gtcgagcagc tcggcctcac cctgcagaag gtcaccgacc
     5581 agctacgcga gaagtacggc ctgtccgacc aagtgaaggg cgtcgtcatc accaaggtga
     5641 cccccaacag cccggcggcc gagaagcagc tccaggcggg tgatgtcatc ctcgaggtcg
     5701 accagaagcc ggtcaccacc ccccaggagg tcaccgatct cgtgggcaag cttcagcagg
     5761 ccaagaagcg ctcggtcctg ctgttcgtcg aacgccaggg cgatccccgg ttcgcggcgc
     5821 tcaggctgac gaagtaatct tgccggagcg cggacctcca ggtccgctca tgttcttccg
     5881 aagcgagcct ctggctcgct caggatctat gagcgcgccg ggaggcgcgc ggtccggaag
     5941 gtgaagacca tgagcggacc tggaggtccg cgctccgatg acgcgccact ggagtggcgc
     6001 gcccccagct taagagccga tccacgtgcg gcggaccgtg aggtccgccc caaggtgcac
     6061 gatatcggcg acgtggccgc gcacgaggcg gccatgcttg tcgtcgaggc gcaggaattt
     6121 ggccgggtag agcgccgcca tcctgagcgc ctcctccagc ggcagcttca gcacgtcgac
     6181 gcagaacctc accgcggtcg ccatgtcgag atgagcgccg gccagcacct ccgcgccgct
     6241 cgggtcggtc caggtcaggc gatcgccgcg tcggtcgatc gtgcgctcgc ccagcctgaa
     6301 ggaggtcgcg gccgagccga cggtcggcat ggcgtctgtc accaggaaga gccgtcccgg
     6361 cgcccgcttg gcacgcagcg cgatcgacag cgccgatggc gcgacgtgca gcccgtcggc
     6421 gatgatcccg caccacaccg cgccggcgtc gaggcccgcc ccgaccaggc cggcggcacg
     6481 gccctgcaac gggctcatgg cattgaagag atgcgtcaca ccggtcgctc ccgcgtcgaa
     6541 cagcgccatc gcctgttcgt aggtcgcgtc ggagtggccg aggctcacga tcacgccccc
     6601 atcgaccaga cgtctcacct gcgcgggctc gacctgctcg ggcgcgacgg tgaccaccag
     6661 gcgcccgatg tcggcggaca gcagcatctc gacatcggca tcggtcatgc gccgcatgaa
     6721 tcgcgggtcg tggacgccct tgcgggccgg tgcgaggtgc gggccctcca ggtgcaggcc
     6781 cgcgacgccc ggaccggcat ggcgaacggc ggccaacgcg gcgcgcgtgg tctctgtgct
     6841 cgtcgtcacc agcgtcggca gcaggcggca ggtgccgaag gtgcgatggg cggcggcgat
     6901 tgcgtccatc gccgcggccg tcggtgtgtc gttgagcaat acgccgccgc cgccgttgac
     6961 ctgggcgtcg atgaagcccg gcaccagcat gccgccatcg atccgctgca cggccgcatc
     7021 ggccggcagg tcggattgcg acgcgatgcc catgatcgcg ccgtcacgga tgagcacggc
     7081 cgccccgtcg tgccagcggt cgccgtcgaa gatgcgcgcg ccggtgaggg cggtgatacc
     7141 ggtcatgtgc cgaccatctt gcgggccaag tcgatggcac cggacagggc gtcgcgctgg
     7201 gcgggcacca ggatgcgcgc caggcgccga ggcagccggc tcgcataggc gtcggccaga
     7261 ccgccggtca gggcgatgcg tttcgcgccc agggcgatca tgcgatcgag cagccgggtg
     7321 acgtcggcga cagcatcggc gaccagccgc cgggcgacgg gatcggcctt gtcggagcag
     7381 gcaaagacca ggggcgcgag ctcgccccag tggctcgggg tcgcggccat ggcccatgct
     7441 cgcatcttcg acgggtcgtt gtcgaagcgg cgcatgatgc ggcgcgtgag cggcgagggc
     7501 gcgatcacgc gctggtgcgc cgccagggcc tggcgcgcgg ccgcatgtcc gacgactgcg
     7561 cctgagccga ggtccgagat caggaagccg tcgccgctga cgcgctcgag cttgccgcgc
     7621 cggcgcacga ggccgttgct cccggtaccg aggatgagca cgccgccatc gcgaccctcg
     7681 tgagcgccga tgcacgccgt ctcggcgtcg ccgcgaatgg tgacggacgc gaagccgaag
     7741 cggcgtgccg ccatcttgcg ggcttgcgca ggatcgtcgg cgcctgcgat tcccatcccg
     7801 gcatgggtac gccgcatcgc cgcccggccg agtccggcct cggcgaaagc ctcggcgctc
     7861 gccgccatga tcgcccgatg ggccttgtcg atgccccagg tcagattggc gggaccgcct
     7921 cgacccgatc ccaggacgtt gccatcggca tcgacgaggc gcgcccggca atgggtgccg
     7981 ccggcgtcga ttccgaggaa gagctcgttc atctgacagg cgaatttgag ccggacatca
     8041 ggcgattctt accaccagct tgccgaagtt ctcgccctta agcagaccca tgaaggctgc
     8101 cggtgcgccg gcgaggccgt cgacgacggt ctcgcggctc ttgagcttgc cttccttcac
     8161 cagcccgccg acctcgttca cgaagtcggc catcagcgca atgtggtcgg agacgatgaa
     8221 gccctgcaag gtcagccgcc gttgcacgat ggtgaacatc ttcggcggtc cggccatcgg
     8281 cgtctggtcc tggtactccg agatcgcgcc acagaaggcg acgcggccga aattgttcag
     8341 ccgctcgaat acggcatgga agatcctgcc gccgacattc tcgaagtcgg catcgatgcc
     8401 ctgcgggcag agcttgtcga gcacggcgcc gacatcgtgc tcggtcttat ggttgaagca
     8461 ggcgtcgtag cctgcctcgc gcaccgccca ggcgcacttg tcttcgccgc cggcgcaacc
     8521 gacgacgcgc gcgccggcaa gcttggcgag ctggcccgcg acctggccga ccgcgccggt
     8581 cgccgccgac acgaacaccg tctcgccggc cttgggcttg cagatgtgcc ggatgccgta
     8641 ccaggcggtg aaggagggca tgccgagcac gccgagatgg gccgacaagg gcgccagcgc
     8701 aggatcgatc ttgcgcaaac ccttgccgtc gtggagcgtg tggctcgccc agttcagcat
     8761 gccgatcacc gtgtcgccct tggcgaagcg cgggttcttg gaatcgacca cctcgccgac
     8821 cgagccgccg gtcaacggct tgccgagctc gaagggcggc gtgtaggagc gcagctcggt
     8881 catgcgcggc cgcatgtagg gatcgagcga caggaagcgc gagcgcacca ggacctcgcc
     8941 gtcggccagc acgggcaggg tcaccttctc ctcgcggaag cagtcggcgg tcacgtcgcc
     9001 cgccggacgc ttggcgagca cgatctggac ggcgtctgtc atgggtcggt cctttcgacg
     9061 aattcggttc ggcggtagcc ctgcaggtag agcagcgcgg tgagatcgcc atggtcgatg
     9121 cgcgccgcca cttcggccgc gaccgcgggc ttggcgtgga aggcgacgcc caggcccgcc
     9181 gccttcagca tcggcaggtc gttggcgccg tcgcccacgg tcacggcgtc ggccggcgaa
     9241 aacccgcgct cggccgccag gcgctgcagg gtggcgagct tggcctcctt gcccaggatc
     9301 ggcagatcga ccgtgccggc aagcgtgcgg ccatcgtgct gtaggccatt ggcggcatgg
     9361 gaatcgaagc ccagcgcctt gtgcaccaag gcggtgaaat gagtgaagcc gccggatacc
     9421 agcgcgcaat ggccatcgtg cttcttcatg gtggcgacca gtgtcgcgcc gcccggcatg
     9481 tagcggatgc gcttggccgc ctcgtcgagc ttggccacat cgagcccctt caacaacgcg
     9541 acccgttcgt tcagcgcgcc agcgaagtcg atctcgccgt tcattgcgcg cgcggtgatg
     9601 ccggcgatct tctcgcgcag gcctaaaaaa tcggccagct cgtccagcat ctcgttttcg
     9661 atcatggtcg attccatgtc ggccaccagc agcttcttgc gccgccccgc cgacggcacg
     9721 accacggcat cgattgcagc catcgcgacc ggccgtgcct cgccgtcgaa gggaatgtcg
     9781 caggcgatct cgggtgccag ccactggggc gtgccgacgc tggcgccctg cgcctgaagc
     9841 acggcaacgg cgttcctgat ggcgccatcg ttgagcgcgg gatgcgccgc gctcgagatc
     9901 aggacgagga cgtttttcac gctccggctc tagcggcggc ccggtggatt tgcaaacaat
     9961 tcgcccgcca tggctcagca acaggttctc gtcatcaccg gcccgaccgc cagcggcaag
    10021 tcggcgttgg cgctcgccgt tgccgcgggg cacggcggca cggtgatcaa tgccgacgcc
    10081 atgcagactt acgatgcctt tccgatcctg acggcgcagc cgacggccga ggaacgacag
    10141 agcgtgccgc atgcgctcta cggcgtgctg ccgctcagcg agaccctgtc ggcggcgcgc
    10201 tggcgcgacc tcgcctcggc cgagatcgaa cgctgcctca cggcgggccg catgcccgtg
    10261 ctgtgcggcg gctcgggcct ctatctccgg acgctgatgc acgggatcgc cgccatcccc
    10321 gacgcgccgg acggcctgcg cgaccaggcc aacgccgagt ggaaggcgat gggcgcggag
    10381 gcgtttcgcg cgcggctggc ggagaaggac tcggcgatcg tcgaacggct gaagcccgga
    10441 gatcgccagc gccatgtccg cgcctgggaa gtctggctgg cgaccggccg gccgctcagc
    10501 atctggcaga agggcgaggg ccagccgccg ccttggcggt tcgccaccgt cctgctcgcg
    10561 ccggagcgcg gctggctcag ggcgcgcatc gagacgcgct tcgacgccat gctgaagatg
    10621 ggcgtgctcg acgaggtgcg cgccgtgttc gaccaaaagc ccgacgcacg ctggcccggc
    10681 ctcaaggcgc acggcgcccc ggagctgttc gcgcatttcc gcggcgagct gacgctggag
    10741 gatgcgcgcc ggatcggcat cgatcacacg cgccaatacg ccaagcgcca gatgacgtgg
    10801 tttcggcacc agatgacacc agatgtggta gtcgatccga cgaccgacct gggcttggag
    10861 caaactgaga aattattgac caaaatcgag acctgaaact ttacgtttcg tgcgattccg
    10921 gttgattcct cccgacccgg cctatacttt ccgcccgccg caaaaccccc gttttgcggc
    10981 acatttgtca gagaggagac ccgtgtcatg aagcccgagg agtccgccac gactggcgcc
    11041 gatctgctgg tgaaagccct gatcgacgag gaagtcgagg tcgtcttcgg ctatccgggc
    11101 ggcgcggtcc ttccgatcta cgactccctc ttcaagcaga accggctgcg ccacatcctg
    11161 gtgcgccatg agcaggcggc cgtgcatgcg gccgagggct atgcgcgctc gaccggcaag
    11221 gtcggcgtgg tgctggtgac ctcgggcccc ggcgcgacca acgccgtgac cggcctcacc
    11281 gacgccctga tggattcggt gccgatcgtc tgcctgaccg gccaggtgcc gacgcacctg
    11341 atcggcaacg acgccttcca ggaagccgac acgaccggca tcacccggcc ctgcaccaag
    11401 cacaactacc tggtgaaggc ggtcggcgat ctggcgcgcg tcgtccacga ggccttttat
    11461 gtcgcccggt cgggccggcc cggaccggtc gtcatcgacc tgcccaagga cgtgctgatg
    11521 aacaagcacg actacgtggc gcccaagaag ccggtgcagc acaagagcta ccgcccgcag
    11581 gtcaagcccg acccgaagaa ggtcgaggag gcgatcgagc tgatcgccgg cgccaagcgg
    11641 ccgatcttct atgccggcgg cggcatcgtg aacgccgggc cgaaggcttc caagctgctc
    11701 acgcagttcg tgcacatgac gggctatccc atcaccaaca cgctgatggg gctcggcacc
    11761 ttcccggcga gcgacaagca gttcctgggc atgctgggca tgcacggcac ctacgaagcc
    11821 aatctggcga tgtatcactg cgacgtgatg atcaacatcg gcgcgcgctt cgacgaccgc
    11881 atcaccggca agctcaccga gttctcgccc aagtcgaaga agatccacgt cgacatcgat
    11941 cccagctcga tcaacaagaa cgtgcgtgtc gacttggccg tagtgggcga tgccggccac
    12001 gtgctggaag agatgatccg cgtgtggaag gcgaggcaac ccaaggtcga tcacaaggcg
    12061 ctgaaggcgt ggtgggccga gatcgacaag tggcgcgagc gcaactgcct cgcctacaag
    12121 caggacaagg agacgatcaa gccgcaatac gcgctggaac gcctctatca ccacatcaag
    12181 gaccgcgacc actacatcac caccgaagtg ggccagcatc agatgtgggc ggcgcagttc
    12241 ctgaagttcg agcagcccaa ccgctggatg acctcgggcg ggctcggcac tatgggctac
    12301 ggcttcccgt cggcgatggg cgtgcagatc gcccatcccg atgcgctcgt catcgacgtg
    12361 gcgggcgagg cctcgatcat gatgaacatc caggagctct cgacggtggc gcagtaccgg
    12421 ctgccggtga agatcttcat cctgaacaac cagtacatgg gcatggttcg gcagtggcaa
    12481 gagctgctgc atggcggccg ctattccgag agctacatgg aatcgctgcc cgacttcgtg
    12541 aagctcgccg aggcgttcgg cgccgtcggc ctgcgctgcc acgaacccga caagctcgac
    12601 gacacgatcc agcagatgat cgccatcaag aagccggtgg tcgtcgacgt gctggtcgac
    12661 aagaccgaga actgcttccc gatgatcccg tcgggcgcgg cgcactacga catgctgctg
    12721 gggcctgacg accgcgccgc caagccggtg tcggaggaag gcatggtgct ggtgtgaacg
    12781 cacccatgat cgcttccagc catacgatct cggtgctggt cgataacgag cccgggatcc
    12841 tggcgcgcgt ggtcggcctg ttctcgggcc gcggctacaa catcgagagc ctgaccgtgg
    12901 ccgagaccga cgccaaggag aacctctcgc gcatcaccat cgtgacggcg ggcacgccca
    12961 tggtgatcga gcagatcaag gcccagctcg accgcctggt gccggtccac aaggtgcgcg
    13021 atctcaccgt cgaaggtccg cacatcgagc gcgagctcgc cctggtgaag gtcaagagct
    13081 cgggcgacaa gcgcgtcgag gcgctgcgtc tcgccgatgt gttccgcgcc aaggtgatcg
    13141 acgccaagat ggattccttc gtcttcgagg tcaccggcaa ctccgacaag gtccagacat
    13201 tcatcggcct gatggagggc ctcggcctgg tcgatgtcgg ccgcaccggc atcgtcgcca
    13261 tgtcacgcgg cggcgacgcg ctgtgatttc cgtcgtctcg accggagcgc gaagcgcgga
    13321 gcggagagac ctcgtctcca cgatttgccg gcaagtcggg gagagaaggc ccctcggctt
    13381 cgcttcgcta cgctcggggc gacggtagtg gactacgccg tcgtactgct gggcctcgcc
    13441 gtcgtccatc tgctggcggt ggcgagcccc gggccctcga cggtgctggt gatccagacc
    13501 gcggcgatcg tcggccggcg cggcggactt ttagcggcct tcgccatgat ggtgggggcg
    13561 ctcgcctggg ccgcggcggc gctctacggc ctgcaggcgc tgttcgccca gttcgaatgg
    13621 ctctacgtcg ccttccgcat aggcggcgcg ttgttcctga tctatctcgc cgtcatgatc
    13681 tggcggcacg cgaaggatcc gctgcccgag atcgcggtcg accgtacggc gcacatgacc
    13741 ggctggcagg gtttcatgcg cgccctgctg ctgcagctca gcaaccccaa gatcatggtg
    13801 ttcttcggca gcatcttcct gtcggtgctg ccgcagaaca cacccggctg gatggacggt
    13861 gcggtgctgg cgatcgtggc ggtgaacgag ttctgctggt tcgccctgct ggcgttgctg
    13921 ttctcgggcg ggccggcgcg ggctttctac cgccgcgcca aggtctggat cgaccgcgtc
    13981 atgggcggcg tgctggcggc cctcggcctt cgcctcattc tcgcagaccg atgatcgagg
    14041 tgacgcgacc ctcgacctcg gcgaggttgg ccggcgtgct ctgcagcacg aacagcgcct
    14101 gcgtacggcc ggcgaagctc aacgggttac cgctttcccg ctcggccatc tcgtagaaga
    14161 acgtgccgcc gggccggcag ctccaggtcg ggctcaggcc ctggacgtag gagccgggat
    14221 ggcgcaggca gacctgggtg accattcggc cgctggcgtc gggcaccgtg ttgacctgcc
    14281 attcgccggc gaagatgcgg ctctgaccga ccacccaggc gtagtccttg ccgtccgccg
    14341 aggagtagtg gatctgcgcc gggccaccac cgcgcgtcca cagccaggtc ttgttgctca
    14401 tggcgcgctg ggcggcgtcg ggcgtggagt tgtcgatggc gccctggatc tgcggcatcg
    14461 gcaccgcagg accgacaggc gcggccggat cgggattgga gcaggctgcc agggcagcgg
    14521 agatcacgag ggtagcgaag aggtgggaac gaaacatgga gggacgctgc cgtgtcccga
    14581 tccgcttgtc tagcgattgg ctgcgggatt ggcgcgcgcc ttgagctgcg tgatcgtgag
    14641 gttgctgagc gtcagcgcaa acggcgcttg cgtgcggccc gccaggccga gcacatcgcc
    14701 gtcgacccgc tcgggaatcc aatggaagac cgagcccgcg gcgcggcaat accattggtc
    14761 gccggcggtc ttggatatgg gatggaccgg atcgcccgga tagcgcaggc aaagccgcgt
    14821 gaccgtctgg cccttgctgt cggtcgcggt ctcgatccgc cattcgccgg ccaggatgcg
    14881 ctcctcgccg cgaaaccagg cgaaatccct gccgtccggc gccgaataat ggatgtgctg
    14941 gccggagctg ctttcggtgc tgcgccaggt cttgccgctg atgaaagcct cagcctgctg
    15001 cggcgtggtc gtggcgttgg cggtgtcgat cgcccgcatc gtgttcgtgc cgtcgcggct
    15061 gccggatact gaggagctgt accaacatcc ggccagggac agtgaagcgg ccgcggcgag
    15121 cagcgggaaa cgaagagcgg tcatgcgtgg gaagcggatt ccaggctggt cattgcaggc
    15181 cgggttgtct agtaagcccc cgttcaatgg ccagacgcac actgccagga ggaattggcc
    15241 ccatgcgtgt ctactacgat cgcgatgccg atgtgaacct gatcaagggc aagaaggtcc
    15301 tggtcgtcgg ttacggcagc cagggccacg cccatgcgat gaacctgcgc gattcgggcg
    15361 tcaaggatgt gcgtattgcg ctgaaggccg gctcggccac gatcaagaag gccgagggtg
    15421 cgggcttcac ggtgatgagc ccggccgacg gtgccaagtg ggccgacatc gtcatggtgc
    15481 tgacgccgga cgagctgcag tccgacatct acaatgccga tctcgcgccg aacatgcgtc
    15541 cgggctcggc gctcgctttc gcgcacggcc tcaacgtgca cttcaacctg atcacgccgc
    15601 gggccgacat cgacgtgttc atgatcgcgc ccaagggtcc gggccacacc gtgcgctcgg
    15661 agtacctgcg tggcggcggc gtgccctgtc tggtggcggt ggcgcagaac tcgtcgggca
    15721 atgccctcga gatcgggctc agctattcgt cggcgatcgg cggcggccgc gccggcacca
    15781 tcgagaccac cttcaaggaa gagtgcgaga ccgatctgtt cggcgagcag gtggtactgt
    15841 gcggcggcct ggtcgagctg atcaaggccg gctacgagac gctggtcgag gcgggctatg
    15901 cgccggaaat ggcctacttc gagtgcctgc acgaggtgaa gctgatcgtc gacctcatct
    15961 tcgagggcgg catcgccaac atgaactact cgatctccaa caccgccgag tacggcgagt
    16021 acgtgtcggg tccgcgcatc gtcaccgccg agaccaaggc cgagatgaag cgcgtgctgg
    16081 ccgacatcca gtcgggccgc ttcgcgcgcg actggatgct ggagaacaag gtcaaccagg
    16141 cctcgttcaa ggccatgcgc aagcggatgt cggagcaccc gatcgaggag atcggcgtca
    16201 agctgcgcgc catgatgccg tggatcaagg aaaaggcgct ggtcgacaag acgcgcaact
    16261 gatcttcgct gggcgcgcgc cactccagtg gcgcgtcatg gtcttccgga ccgcgagcct
    16321 ccggctcgct catgagcgcg ctggaagcgc gcggtccaaa agagctgaga agacgcgcca
    16381 ctggagtggc gcgcccccag cccgctagat gatgtagccg ccgccggccg cgtcgaccat
    16441 ggcgccggtg atgaaagacg cctcgtcgga cagcagccac aggatcgtct cggcgatctc
    16501 gtggccctcg ccgacgcggt gcatgggaat cgactcctcg atgcgggcgc ggaaggcggg
    16561 ttccgcgagt gccttctcgg tcatctcgct caacaccatg cccggccgga ccgcgttgac
    16621 gcggacgccc tcggccgctg cctcgcgggc gaagcccttg gtgaaggaat cgaccgcgcc
    16681 cttggtcgcc gcgtaggcgc tggagcccag ccggccgccg atcgtcgagg ccatcgacga
    16741 gacattgacg atggcgccgc ccttgccgcc gttcctggtc gacatgcgct tcgcggcctc
    16801 gcggcaacac aacatcagcc cgatagcgtt gatcgcgaag agattcgcaa gccgcgctgc
    16861 gtcgtattcg tcgacccgcg tgcggtatcc aatgcctgcg ctgttgacga gatgggtgat
    16921 cggaccgagc gcccgctctg tcgccgcgaa cagccgcacg atgtcggcct cgtttgccat
    16981 gtccgcgggc agggcgacgg cgcttccgcc cgccgcctcg atgtcggcca cgatctgctt
    17041 ggcttgcgtg tcgcgcgagc ggtagttgac cgcgaccttg tagccgcgtt tcgccgcgcg
    17101 acgcgcggtc tcggcgccaa tgcccgaggc tccgccggtg atcaggagga ttttcgtcat
    17161 tgagctcatt gctttccgaa cacgaagccg ccgccggacg cgtcgagcgt gaccccggag
    17221 atgaagctcg cttcgtcaga cagcagccag acgatggcgt tggcgatctc ctcggcctgg
    17281 ccgacgcggc ccatggcgat ggtcgattcg atcgcctcgc gcgtctcgcg atcagacagc
    17341 gtcttctcgg tcatctccgt ctcgatcatg ccgggccgca gcgagacggc gcggatgcct
    17401 tcgagcgcca catccttggc gaagcccatg gtgaaggagt cgaccgcggc cttgcttgcg
    17461 gcataggccg cagcgcccgg ccggccgccg atggtgccgg ccatcgacga gacgttgacg
    17521 accacgccgc cttcgccgcc gcgcttggtc gacatgcggc gcgccgcttc ccggcagcac
    17581 agcatcaggc cgaccgtgtt cacggtgaac agtctctcca gggcgcccgc atcgaaatcc
    17641 gccacgcgtg agttgaggcc gatgccggcg ctgttcacca gatgcgtgat cggcccgagc
    17701 gccttctcgg cagcgtcgaa caggctcagg atatcggctt cacgtgaaac gtccgccggc
    17761 aacgcgatcg cctggccgcc cgtgccggtg atgtccgcca cgaccttctt cgcctgcgcg
    17821 tcgcgcgagc ggtagttgat ggcaaccttg tggccgcgcc gggcggcaag cttcgcggtc
    17881 gccgcgccaa tgccgctggc gccgccggtg atcagcaggg tcatcctttc aacgctcctc
    17941 cggtcagacc atgcacgaga tagcgcctga cgaggaagga gaagatcagc actggcagca
    18001 tgatcatggt gccgccggcg gcgatgcggc cccattccca gccttcgtag ttcatgaagt
    18061 tcacgacggc gaccggcgcg gtcatggcct cggtgcgggt caggatcagg gcgaagaaga
    18121 agtcgttcca ggcaaacagg aagcagagga tggcggtggc ggcgagcccc ggcccggaga
    18181 gcggcaggat gatgcgataa aagccctgcc acatggtggc gccgtcgatc caggcggcct
    18241 cctccagcga gcgcggcagc tggtcgtaga acggccgcat catccagatc accagcgaca
    18301 ggttgaaggt gaggtagatg atgatgaggc ccgtcagcgt gtccaagagc tcgaggtgcc
    18361 ggtagaccag gaagtagggg atggtgaagg cgatcggcgg ggccatgcgg ctggccagga
    18421 tccacagggt gatcgtgccg ccggcgcggg tggtccagcg cgacagggcg taggccgccg
    18481 gcacgccgat caagagcgac agcaccgtcg agaccacgcc cacgatcagg ctgttggcga
    18541 aggagttgcg gaagtccgac gtccacaggg cagcgtagtt ggcccaggtc gcctcgaaga
    18601 ggacccgtgg cgggaagcgg aagatctcgg cgttggtctt gaacgacatc aggaccagcc
    18661 agaggaaggg cgacagcgcc agcagcgcga gcacgatcgc cagggcgtgc atcaggaagc
    18721 ggtcgcgggc gcgcgacgac ttgctagtca atgcgcgctc cccagccgac gacgcgcacg
    18781 atcacccagc tcagcacgat ggtcgcggcc agcagcacca cggtgatggc gctggagaag
    18841 cccaggtagg agaaattgaa ggcctgcagg taggagtagt agttcgtgac ctcggtgagg
    18901 ttgcccggcc cgccgtcggt caggatgaag atcagcggga aggccttgat cgaatcgatc
    18961 agccggaaca gcccggcgac cagcagcacg ccctggacga agggcagcgt gatgaaccag
    19021 gtgagctgcc aaggcgaggc gccgtcgacc ttggcggcgt ccagaagctc ctgcggcatc
    19081 atctgcaggg cggccagcac catcagcatg gtgaagggga accattccca ggtgtcggcg
    19141 atgatgatcg aggtcagcgc ccactgggga tcggtgatca gcgccggcac gttccagccc
    19201 aaagctcgga acaggccgtg catggggctg atgtcgggcg tgtagatcac tttccagatg
    19261 atggcgacga cgatcggcgg cagcaccatg gggatcagga acaccgtgcg cagcgcctcg
    19321 aggagccgcg tgcgcatgtt gagcagcagg gcgaggccga gccctatcag gagctgcagc
    19381 agcaccgtcc agaaggagag cttgatctgg acccagatgg agttgtggaa gcgcgtgtcg
    19441 gcccagagct ggcggtagct ctccaacggc tgcgagaagt cccacagcgt ctcgggccgc
    19501 gtcaggttga gcggcgtgaa gctggtggcc agcagataga gcgacggcag caaggtgatg
    19561 atcgccagca ccgcgagcga cggcgccacg cagaaggcga agaagcggtg ttgctgtttg
    19621 gctatcctgc ccagcgtcgc acttctttcc ctcgacgggt tcttgctcct ctcccccgct
    19681 tgggggagag gatgggagag ggggtgacgc acgtcgattt
//
