LOCUS       c00175_NZ_BKAJ..       14459 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BKAJ01000175.1 Reyranella soli strain NBRC 108950 sequence175,
            whole genome shotgun sequence.
ACCESSION   NZ_BKAJ01000175
VERSION     NZ_BKAJ01000175
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:01:08
            Original ID  :: NZ_BKAJ01000175.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14459
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14459
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1825:4459]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1826..4459
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14459
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14459
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(73..1098)
                     /locus_tag="ctg175_1"
                     /transl_table=11
                     /translation="MLHKLIAATALGGAVALSALPASAGQTFDAVKAKGFVQCAVNTGL
                     AGFSMADSQGKWTGLDVDLCKAIAAAMFGDAEKSKFTPTTAQQRFVALQSGEVDVITRN
                     ATQTLLRDTSLGFNIAGVNFYDGQGFLVPAKSNIKSAKELNGATVCVQPGTTTELNLAD
                     YFRKQKMTFKPVLIEKLDELLQAYAAGRCDAYTTDASGLAAVRVAQLAGKGEHVILPER
                     ISKEPLGPIVRHGDDQWFDLVKWVLMGMIEAEEMGITSKNVDELLKSDDPSIKRFLGVT
                     PSFGKAVGVDEKWMYNVIKQVGNYGESYERNVGTATPLKLERGQNALWTNGGLLYAIPF
                     R"
     CDS             complement(1149..1580)
                     /locus_tag="ctg175_2"
                     /transl_table=11
                     /translation="MRRFRQSCSNNSDTIPDVELLLDTHVFIWWNVDPARLSEGTRSAI
                     GDAENRVVVSAASVWEISIKRMIGKLAFNHDTLDAIAKAGFEALSITPGHADAAGSLPL
                     HHTDPFDRLLVAQARIERLVLVTQDRRLVPYGVPLLGAV"
     CDS             complement(1531..1776)
                     /locus_tag="ctg175_3"
                     /transl_table=11
                     /translation="MTKVFNLYEAKNQLSSLVDRAASGEEIVIAKHGQPMAKLVPVPRP
                     KKERRKPQNFLGVTYVADDFDAPLPPELLKQFGYDP"
     CDS             complement(1826..2605)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_4"
                     /sec_met_domain="Fer2_3 (E-value: 2.7e-36, bitscore: 114.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.5e-11, bitscore: 35.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFALPANSKIGTGETYKAPGGAKNIKLFKVYRWTPDDGKNPSV
                     DTYEVDMDTCGPMVLDALIKIKNEMDSSLTFRRSCREGVCGSCAMNIDGTNTLACTKYI
                     SDVKGDIKIYPLPHMPVVRDLVPDLNVPYAQLTSIEPWLKTSTQPPTRERLQSPEERAK
                     LDGLWECILCFCCSTSCPSYWWNGERYLGPAILLQAYRWLADSRDEAKGERLDQLEDPF
                     RLYRCHTIMNCTKTCPKHLNPAKAIAEIKKMMVERTI"
     CDS             complement(2621..4459)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 382.9; E-value:
                     6.9e-117)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg175_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-117,
                     bitscore: 382.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3e-46, bitscore:
                     147.3, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVGKNEGGDAGTLNIGGTSYTVIDHEYDVVVVGAGGSGLRATF
                     GMANKGFKTACITKVFPTRSHTVAAQGGISAALGNMGPDDWRWHMYDTVKGSDWLGDQD
                     SIEYMCRDGIPAIIELEHFGVPFSRTPEGKIYQRPFGGMTTEYGKGIAHRTCAAADRTG
                     HAILHTLYQQSLRNHAEFFIEYFALDLIMDEGVCRGVMAWNLDDGTIHRFRAHKTVLAT
                     GGYGRVYQTATSAHTCTGDGGAMVLRAGLPLQDLEFVQFHPTGIYGAGCLITEGVRGEG
                     GYVTNGNGERFMERYAPSAKDLASRDVVSRSMTIEIREGRGCGPNKDYIELHVEHLDPK
                     VIHERLPGIAETARIFAGVDVTRQPIPILPTCHYNMGGIPANYHCDAMTVKDGDPFYAV
                     PGLMALGEAASIGVHGANRLGSNSLLELVVFGRSAANRVAEQLKPGETHKQIKDAGQEA
                     IARLDRARHAKGGTPTAQLRALMQKTMQNDCAVFRTTQSLKDGCANMDKVFAGKDDIRV
                     KDRSMIWNSDLMETLEFENLILQAMGTMYSAANRHESRGAHAHEDFPERDDKNWLKHTV
                     VWVDEKTGKTRIDYRPVNLQPMSNDVQSFPPKARVY"
     CDS             complement(4462..4848)
                     /locus_tag="ctg175_6"
                     /transl_table=11
                     /translation="MDSDRRTHLSRARGLGSAKEGVHHFWAQRVTAVALIPLVVWFAVS
                     LIMMSGADYGVVRAWIGSPVVMVLLVLTIVIGLHHGQLGMQVVVEDYVHNEGMKLALIV
                     LMRFIAVFFGLAAIVAILRIGFGG"
     CDS             complement(4859..5257)
                     /locus_tag="ctg175_7"
                     /transl_table=11
                     /translation="MSVANRPVHRPLSPHLQVYKPQLTSMLSILHRATGMALSVGALYL
                     VVWVVFASASPRTYAMFQSFNVSILGRIFLGGWLFCAFYHLCNGIRHLFWDMGYGFELK
                     DAYRSGWIVVAVSLAATIVSWIVGLRLA"
     CDS             complement(5254..5397)
                     /locus_tag="ctg175_8"
                     /transl_table=11
                     /translation="LAADAAARLISLRNPRLKVHVAATFVDLKQASAKKAQPMSAIGVF
                     AR"
     CDS             complement(5370..6425)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MaoC_dehydratas"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_9"
                     /sec_met_domain="MaoC_dehydratas (E-value: 4.2e-09,
                     bitscore: 26.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTSTGNFFEDFRVGQEFRHATPRTLTEADAALNVGLYGSRFAI
                     NSSDEFARSIGLLRAPLDDLLVFHVVIGKTVNDISLNAVANLGYAEFRWGVPVYPGDTV
                     QSKSTVLGLRENSNKASGVVWVRSTGTNQKGEMVLDYVRWVMVHKRDPQAAVGAPVVPK
                     TAAAVAPADLIVPEGLKLGGYDDVVAGSPHRWEDYEPGERIDHVSGITLEDSDHMFSTR
                     LYQNTARVHFDAFAGKNTRFGRRLAYGGHVISLARALSFNGLANGFRLAAINAGSHVGP
                     TFGGDTIYAWSEVLEKAPLPGRADLGALRMRLIAAKDFPCDSFPGKHADGKYHPAVTLD
                     LDYWLLMPRRA"
     misc_feature    complement(5371..5373)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     misc_feature    complement(6252..6254)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(6422..8056)
                     /locus_tag="ctg175_10"
                     /transl_table=11
                     /translation="VRQEQRGDGVARSVGRDLETDQGRRDAPCRVPAHRDHLDLVGRCV
                     GAAQAGDQCEARPFQQAARGGQRIGHGRDLGPGQVLQLEVVGRYEVGQGKGALAEEGVD
                     AGLNVDAGVDVAQHRVAAPHRLGVGGPHLACGVEHHVAQRGIADIAREQRVAARQHAQG
                     LDAGHDVGDLVRRRRAATPRAIAGMVRELDRVDRPDLVAQSLQGKSRSPIAHVAVGNMA
                     LKREKAHAAGHLATRRPAIIVRRVFQGAVMSQTVRPRRSVLYMPGANTRALEKARTLPA
                     DALIFDLEDAVAPEAKEAARTNVVLAAESRAYGKREIVIRCNGLGTPWGEADIAAIAQS
                     GADAILVPKVESATQVTHVVSLLDTAGAPSTMAVWAMMETPKGILRAEEIAGAHPRLGL
                     FVMGTNDLVKDMRARHTPMRLPMITALGIGMLAARAHGLAILDGVYNDIQDSEGFRAVC
                     QQGLEMGFDGKTLIHPSQVEPCNEIFAPSAAELEMAGKIVAAFKAAQAEGKGVVTVDGR
                     MIENLHVEQAERALALASAIKELQAAA"
     CDS             8229..8924
                     /locus_tag="ctg175_11"
                     /transl_table=11
                     /translation="MNVPGFHFNPIALAIEGAAIGFLIAVPVGPAAVLCIRRSITVGAV
                     AGYMTGVGAALGDAVFGAVAAFGLSIVEQFVIEREKWLLGIGGIGLMIMGWVTMRHRPR
                     TVGDPVADDREHQVATHFHYASSSFFITVFNPLTVMAFGAAFAGRNLAGVGANLADAAL
                     LVAAVFCGALAWWAIICTAAVSLRHRFTGVGMLWLNRASGAVILGFGVVALISLLPLPW
                     KQIGHALGL"
     CDS             8943..9881
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_12"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-18, bitscore:
                     58.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVLLDPTKFQDALLTAKGEERAHVALRSLETLWFNTGTLCNLS
                     CQNCYIESSPRNDRLAYLSAAEVRVYLDEIKRDGHGTKLIGFTGGEPFMNRELPAMLED
                     VLSRGLKAMVLTNAMKPMHRMKPALLGLLARYGRNLTVRVSVDHYDKTLHEKERGAHTW
                     KPTIDGLVWLAQSGFDVHVAGRHFSDETDAQVRAGYARLFAALGIAIDAASPVSLVLFP
                     EMDARVDVPEITTACWGILKKSPDSVMCASARMVVKRKGATQPAVVACTLLPYDPQFEL
                     GNTLAESVGAVRLNHPHCAKFCVLGGAACSQ"
     CDS             9878..10555
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_13"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.7e-13,
                     bitscore: 41.4, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTTDIDVVIPTLNAARSLAHTLESLRGDHDLKLSITVCDGGSRDD
                     TASIARQAGAAVLEIEPGRGKQLAAGAMAGGAPWLLFLHADTRLSAGWAAAARQLMARP
                     ARKAGYFRLRFDSADPRARRIERLAAWRCRTFGLPYGDQGLLIERAFYQQLGGFHALPL
                     MEDVDFVRRIGRRNLLPLDADAITSAARYERDGWLARPMRNLGCLALYFAGLPPTVIRR
                     LYG"
     CDS             10552..11139
                     /locus_tag="ctg175_14"
                     /transl_table=11
                     /translation="MKRHLVIFARVPQFGRVKQRLAEAIGPLAAMRFYRQTLDRQIRTL
                     SRDRRWTVWLFVTPDHVLDHPAWHRANVRGQGRGDLGRRMKRPFRLLPPGPLVLVGSDI
                     PAMQPRHIVRAFALLGDHDLVFGPATDGGFWLIGARRGRPLPRSLFAKVRWSTQHALAD
                     TLATIPPGYTTAIADTLDDVDDANDLRRWHGC"
     CDS             11179..11901
                     /locus_tag="ctg175_15"
                     /transl_table=11
                     /translation="MPASFPTQPAIGLFEAIYTARSLRHFKPDPVPPALIERVLDAAIR
                     ASSGGNTQHWTFLVVRDAEKRRQLGALYRQASDYQSAVYAARPKPEHLSEAQYGQFLAN
                     SGYLWDHMADAPVILVPCLARREPPERTSLPEVVQARYADHLANVQRISGSSIYPAIQN
                     VILACRALGLGTVITTNHILLENEVKAVLGIPEHIATFALMPIGYPTRKYGPLTRKPVA
                     EVTFADTWGNPWPDTAAS"
     CDS             complement(11924..13174)
                     /locus_tag="ctg175_16"
                     /transl_table=11
                     /translation="VRPYHAELHNNLGVALRLAGKLEASVSHHRLSLAADPDNPALHSN
                     LGNALRAANRLDEAVKHHFHSITLNRDYGEGFFNLALCLRDLGRIDEAVGCLGRALALN
                     PDNRRARVELALALLMRGELAQGFAAYEARKRLPETPAPDFRQPAWDGAPIGGKRILLY
                     PEQGLGDVLLFVRFARELKRRGATVIVLCQALLKDLLGTVDFIDHVVAEGEPLPDFDLH
                     ASMVSLPHLCRADFDAPALQAPYLKAPVDSRIKLGRIEKAKLSVGIYWAGMPGRPQDRQ
                     RSVPFGRFMEFSGDPELLLFSLQGGVHQKDIQTFGAGGLVHDVGRGIFDFAEAATALSQ
                     LDLLISIDAPIAHLAAAMGIQTWVLSPSTVDWRWQLGGTRAPWYPSARLFRQPRPGDWD
                     AVFADVRRELEQLKRRS"
     CDS             13226..13393
                     /locus_tag="ctg175_17"
                     /transl_table=11
                     /translation="MGLRRQSKLLDECVIATEQRRWHSTGLRFRAERVKRRDVVHPLIL
                     HEISFLTTCS"
     misc_feature    13358..13360
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     misc_feature    13376..13378
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(13463..14425)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Semialdhyde_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Semialdhyde_dhC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg175_18"
                     /sec_met_domain="Semialdhyde_dh (E-value: 6.6e-26,
                     bitscore: 81.9, seeds: 157, tool: rule-based-clusters)"
                     /sec_met_domain="Semialdhyde_dhC (E-value: 4.3e-58,
                     bitscore: 187.1, seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQILAERNFPADDVVALASARSAGKQTSFGENGVLKVQDLAKFD
                     FKGIDIVLSSPGAKVSAEHSPRAAKAGAVVIDNTSYWRMDPDVPLVVPEVNAHAIAGYK
                     GRGIIANPNCSTIQMVVALKPIHEAAGIKRVVVSTYQSTSGAGKEGMDELLNQTKSFFV
                     NQTLEAKKFTKGIAFNVIPHIDVFMDDGSTKEEWKMVVETKKILDPKIKVHATCVRVPV
                     FIGHAEAVNLELERPLDEHEARRVLAAQPGVLVVDRRENGGYVTPQEVTGQDGVFVSRV
                     RTDPTVDNGLSLWIVSDNLRKGAALNAVQIAEELIRGYI"
ORIGIN
        1 ttcatgagcg cgcaggatgc gcgcggtcca ggagaccatg acgcgcgact ggagtcgcgc
       61 gcccccagca gatcagcgga acgggatcgc gtacagcagg ccgccgttgg tccacagcgc
      121 gttctggccg cgctcgagct tgagcggcgt ggccgtgccg acgttgcgct cgtagctctc
      181 gccgtagttc ccgacctgct tgatgacgtt gtacatccac ttctcgtcga cgccgaccgc
      241 cttgccgaag ctcggcgtga cgcccaggaa gcgcttgatg gagggatcgt cgctcttcag
      301 cagctcgtcg acgttcttcg aggtgatgcc catctcctct gcctcgatca tgcccatcag
      361 cacccacttc acgagatcga accactggtc gtcgccatgg cgcacgatcg ggccgagcgg
      421 ctccttggag atgcgctcgg gcaggatcac gtgctcgccc ttgccggcga gctgggcgac
      481 gcgtacagca gccagccccg aagcgtcggt ggtgtaggca tcgcagcggc cggcggcgta
      541 ggcctgcagc agctcgtcga gcttctcgat cagcaccggc ttgaaggtca tcttctgctt
      601 gcggaagtag tcggcgaggt tgagctcggt ggtggtgccg ggctgcacgc agaccgtggc
      661 gccgttcaac tccttggcgc tcttgatgtt gctcttggcc ggcaccagga agccctggcc
      721 gtcatagaag ttgacgccgg cgatgttgaa gccgagcgag gtgtcgcgca gcagcgtctg
      781 cgtggcgttg cgcgtgatga cgtcgacctc gcccgactgc agggcgacga agcgctgctg
      841 cgccgtggtc ggcgtgaact tcgacttctc ggcatcgccg aacatggccg ccgcgatcgc
      901 cttgcagaga tcgacgtcga gccccgtcca cttgccctgg ctgtcggcca tggaaaagcc
      961 cgccaggccg gtattgaccg cgcactgcac gaagcccttg gccttgacgg catcgaacgt
     1021 ctggccagcc gacgccggca gcgctgagag agcgacggca ccgccaagcg cggtcgccgc
     1081 aatgagtttg tgaagcatcc ctgacccctg ttatttgtcg agccagcata gcaaaagccg
     1141 cgcctacgtc agaccgctcc gagaaggggc actccgtaag ggaccaaacg gcggtcctgc
     1201 gtcacgagaa ccaagcgttc gatccttgct tgggcgacca acaatcgatc gaaaggatca
     1261 gtgtgatgca acggcagcga tcctgctgca tcggcgtgac ctggcgttat gctgagcgcc
     1321 tcaaatccag ccttggcaat ggcgtccagc gtgtcgtgat tgaaggcaag cttgccgatc
     1381 atacgcttga tcgaaatttc ccagacgctg gcggcgctca ctacaactct gttttccgcg
     1441 tcaccaatgg ccgaccgcgt tccctcgctc aaacgcgcag ggtcgacgtt ccaccaaatg
     1501 aacacatgcg tgtcgagcag caactccacg tcagggatcg tatccgaatt gtttgagcaa
     1561 ctctggcgga agcggcgcat cgaaatcgtc cgccacgtac gtcacgccta ggaagttctg
     1621 cggtttgcga cgttctttct tggggcgcgg tacgggcacg agcttagcca tcggctggcc
     1681 atgcttggcg atgacgatct cctcgccgga cgcagcacga tccaccagcg atgaaagctg
     1741 gttcttggct tcgtagaggt tgaagacctt ggtcatgaga atttggccaa cttggccaaa
     1801 ttctacatcc cagctgccaa gtcggtcaaa tcgtccgctc gaccatcatc ttcttgatct
     1861 cggcgatggc cttcgccggg ttcaggtgct tggggcacgt cttggtgcag ttcatgatgg
     1921 tgtggcagcg atacagccgg aacggatcct ccagctggtc gagccgctcg cccttggcct
     1981 cgtcgcggct gtcggccagc cagcgatagg cctgcagcag gatcgccggg ccgagatagc
     2041 gctcgccgtt ccaccagtag gacgggcacg aggtcgagca gcagaagcac aggatgcact
     2101 cccacaagcc gtcgagcttg gcgcgctcct cgggcgactg caggcgctcg cgcgtcggcg
     2161 gctgggtcga ggtcttcagc cacggctcga tcgaggtgag ctgggcgtag ggcacgttga
     2221 ggtcgggcac caggtcgcgc accaccggca tgtgcggcag cgggtagatc ttgatgtcgc
     2281 ccttcacgtc ggaaatgtac ttggtgcagg ccagcgtatt ggtgccgtcg atgttcatcg
     2341 cgcacgagcc gcacacgccc tcgcggcacg agcgacggaa ggtgagcgag ctgtccatct
     2401 cgttcttgat cttgatcagc gcgtcgagaa ccatcggacc gcaggtgtcc atgtcgactt
     2461 cgtaggtgtc gaccgacggg ttcttgccgt cgtccggcgt ccagcgatag accttgaaca
     2521 gcttgatgtt cttggcgccg cccggcgcct tgtaggtctc gcccgtgccg atcttggaat
     2581 tggcgggcag tgcgaactca gccatcgctt cctctcgaac tcagtacacg cgagccttgg
     2641 gcgggaacga ctgcacgtcg ttgctcatcg gctgcaggtt gaccgggcgg tagtcgatac
     2701 gggtcttgcc ggtcttctcg tcgacccaca cgaccgtgtg cttcagccag ttcttgtcgt
     2761 cgcgctcggg gaaatcctcg tgcgcatgcg caccgcggct ctcgtggcga ttggcggccg
     2821 agtacatggt gcccatcgcc tgcaggatca ggttctcgaa ctccagcgtc tccatcaggt
     2881 cggagttcca gatcatcgag cggtccttga cccggatgtc gtccttgccg gcgaacacct
     2941 tgtccatgtt ggcgcagccg tccttcaggc tctgcgtggt gcggaacacc gcgcagtcgt
     3001 tctgcatggt cttctgcatc agcgcgcgca gctgggccgt cggcgtgccg cccttggcgt
     3061 ggcgtgcccg gtcgaggcgg gcgatcgcct cctggccggc gtccttgatc tgcttgtgcg
     3121 tctcgccggg cttcagctgc tcggcgacgc ggttggcggc ggagcggccg aacacgacga
     3181 gctcgagcag cgagttggag cccaggcgat tggcgccgtg cacgccgatc gaggccgcct
     3241 cgcccagcgc catcaggccg ggcacggcat agaacggatc gccgtcctta accgtcattg
     3301 catcgcagtg atagttcgcc gggatgccgc ccatgttgta gtggcaggtc ggcaggatgg
     3361 ggatcggctg gcgggtgacg tcgacgccgg cgaagatgcg cgccgtctcg gcgatgcccg
     3421 gcaggcgctc gtggatcacc ttcgggtcga gatgctcgac gtgcagctcg atgtagtcct
     3481 tgttgggacc gcagccgcgg ccctcgcgga tctcgatggt catcgagcgg ctgacgacgt
     3541 cgcggctagc gaggtccttg gccgacggcg catagcgctc catgaagcgc tcgccgttgc
     3601 cgttggtgac gtagccgccc tcgccgcgca cgccctcggt gatcaggcag cccgcgccgt
     3661 agatgccggt cggatggaac tgcacgaact cgaggtcctg cagcgggagg ccggcgcgca
     3721 gcaccatggc gccgccgtcg ccggtgcagg tgtgggccga ggtcgccgtc tggtagacgc
     3781 ggccgtagcc gccggtcgcc agcaccgtct tgtgggcgcg gaagcgatgg atggtgccgt
     3841 cgtcgaggtt ccaggccatg acgccgcggc acacgccctc gtccatgatc aggtcgagcg
     3901 cgaagtactc gatgaagaac tcggcgtggt tccggagcga ctgctggtag agcgtgtgca
     3961 ggatggcgtg gccggtgcgg tcggcggcag cgcaggtgcg atgcgcgatg cccttgccgt
     4021 actcggtggt catgccgcca aacgggcgct ggtagatctt gccctcgggc gtgcggctga
     4081 acggcacgcc gaaatgctcc agctcgatga tcgccgggat gccgtcgcgg cacatgtatt
     4141 cgatggagtc ctggtcgccc agccagtccg accccttgac ggtgtcgtac atgtgccagc
     4201 gccagtcgtc gggacccatg ttgcccagcg ccgccgagat gccgccctgc gccgccacgg
     4261 tgtggctgcg ggtcgggaac accttggtga tgcaggcggt cttgaacccc ttgttggcca
     4321 tgccgaaagt cgcgcgcagg cccgagccgc ccgcgcccac caccacgacg tcgtactcgt
     4381 ggtcgatgac ggtgtaggac gtgccgccga tattgagggt gcccgcatcg ccgccttcgt
     4441 tcttgccgac ctcggccatt ctcagcctcc gaatccgata cgcaggatgg ccacgatggc
     4501 ggccagcccg aagaacaccg caatgaatcg catcaggacg atcagcgcga gcttcatgcc
     4561 ttcgttgtgg acgtagtcct cgaccacgac ctgcatgccg agctgaccgt gatgcaggcc
     4621 gatgacgatg gtcagcacca gcaggaccat gacgaccggc gagccgatcc aggcgcgcac
     4681 gacgccgtag tcggcgccgc tcatcatgat cagcgagacg gcgaaccaca cgaccagcgg
     4741 gatcagcgcc accgcggtga cgcgctgcgc ccagaagtga tgcacgcctt ccttggccga
     4801 gccgaggccg cgggcgcgcg agagatgagt gcgacgatcg ctgtccatca gcccctcctc
     4861 acgccagcct gaggccgacg atccacgaga cgatcgtggc ggcgagcgac acggcgacga
     4921 cgatccagcc gctgcgatag gcgtccttca gctcgaagcc gtagcccatg tcccagaaca
     4981 ggtgccggat gccgttgcac aggtggtaga aggcgcagaa cagccagcca ccgaggaaga
     5041 tgcgaccgag gatcgagacg ttgaagctct ggaacatggc gtacgtccgg gggctcgccg
     5101 aagcgaacac cacccagacc acgagataga gagccccgac cgaaagtgcc atgcccgtgg
     5161 cgcgatgcag gatcgacagc atcgaggtga gctgcggctt gtagacctgc aaatgtggag
     5221 aaagcggccg atgtaccggc cgattggcga cgctcatcgc gcgaaaaccc ctattgccga
     5281 catcggctga gcttttttag cgctcgcctg cttcaagtca acgaaagtcg ccgcgacgtg
     5341 caccttaagt ctcggatttc tcagcgaaat taagcgcgcc gcggcatcag cagccaatag
     5401 tcgagatcga gcgtgacggc cgggtgatac ttgccgtcgg cgtgcttgcc cgggaaggaa
     5461 tcgcagggga agtccttggc cgcaatgaga cgcattcgca acgcgcccag atccgcacgg
     5521 ccgggcagtg gcgccttctc cagcacctcc gaccaggcat agatcgtgtc gccgccgaag
     5581 gtcgggccga catggctgcc ggcgttgatg gccgccaatc ggaagccgtt ggcgagaccg
     5641 ttgaaggaga gcgcgcgcgc cagcgagatg acgtggccgc cgtaggcgag ccggcggccg
     5701 aagcgcgtgt tcttgccggc gaaggcgtcg aaatggacgc gcgcggtatt ctgatagagc
     5761 cgcgtcgaga acatgtggtc ggaatcctcg agcgtgatgc cgctcacatg gtcgatgcgc
     5821 tcgccgggct cgtaatcctc ccagcgatgc ggggagcccg ccacgacgtc gtcgtagccg
     5881 ccgagcttca gcccctccgg cacgatcagg tcggccggcg ccaccgccgc cgcggtcttc
     5941 ggcacgaccg gcgcgccgac cgccgcctgc ggatcgcgct tgtgcaccat cacccagcgc
     6001 acgtagtcca gcaccatctc acccttctgg ttggtgccgg tcgagcgcac ccagacgacg
     6061 ccgcttgcct tgttggaatt ctcgcgcagg ccgagcaccg tcgacttcga ctgcaccgtg
     6121 tcgccgggat agaccggcac gccccagcgg aactcggcat agccgaggtt ggccacggcg
     6181 ttgagcgaga tgtcgttcac ggtcttgccg atcacgacgt ggaacaccag gagatcgtca
     6241 agtggcgcgc gtaaaaggcc gatcgagcgc gcgaactcgt ccgacgagtt tatggcgaag
     6301 cgcgagccgt agaggccgac gttcagcgcc gcatcggcct cggtcagcgt gcgcggcgtg
     6361 gcgtggcgga attcctggcc aacgcggaag tcctcgaaga aatttcccgt gctggtcttg
     6421 ctcatgccgc ggcctgcagt tccttgatgg ccgaagcgag cgccaatgcg cgctcggcct
     6481 gctcgacatg caggttctcg atcatgcggc cgtcgaccgt gaccacgccc ttgccttcgg
     6541 cctgcgcggc cttgaaggcg gcgacgatct tgcccgccat ctcgagctcg gcagccgagg
     6601 gcgcgaagat ctcgttgcag ggctcgacct gactgggatg gatcagcgtc ttgccgtcga
     6661 agcccatctc caggccctgc tggcagacgg cgcggaagcc ctcgctgtcc tggatgtcgt
     6721 tgtagacgcc gtcgaggatc gcgagcccat gggcgcgggc cgccagcatg ccgatgccga
     6781 gcgcggtgat catgggcagc cgcatcggcg tgtggcgcgc gcgcatgtcc ttcaccaggt
     6841 cgttggtgcc catgacgaac aggccgagcc gcggatgggc gccggcgatc tcctcggcgc
     6901 gcaggatgcc cttgggcgtc tccatcatcg cccacaccgc catggtgctg ggcgcgcccg
     6961 ccgtatcgag cagcgacacg acgtgcgtca cttgcgtcgc gctctcgacc ttgggcacca
     7021 ggatcgcgtc ggcgccggac tgggcgatgg cggcgatgtc ggcctcgccc cacggcgtgc
     7081 cgaggccgtt gcagcggatg acgatctcgc gcttgccgta ggcgcggctc tcggccgcca
     7141 gcacgacgtt ggtgcgcgcc gcctccttgg cctcgggcgc cacggcgtcc tcgaggtcga
     7201 agatcagcgc gtcggccggc agggttctgg ccttctccag cgcgcgcgtg ttggcgcccg
     7261 gcatatagag gacgctgcgg cgcgggcgga cggtctgcga catgacggct ccctgaaaaa
     7321 cgcgccggac tataatggcg ggcctccttg tggcaaggtg gcccgcggca tgcgctttct
     7381 ctcgcttcag agccatgttg cctacggcta cgtgggcaat cgggctgcga cttttccctt
     7441 gcaacgattg ggccacgagg tctgggcggt caacacggtc gagttctcga accataccgg
     7501 ctatggcgcg tggcgtggcc gcacggcgcc tgcggaccag gtcgccgaca tcgtggccgg
     7561 catcgaggcc ctgggcatgt tgtcgcgctg cgacgcgctg ctcacgggct atgtcggcga
     7621 tgccgcgctg ggcgacgtgg tgctcgacac cgcacgcaag gtgcgggccg ccaacgccaa
     7681 ggcggtgtgg tgctgcgacc cggtgctggg cgacgtcgac accggcatct acgttaagcc
     7741 cggcatcgac accttcttcc gcgagcgcgc ccttcccctg gccgacctca taacgcccaa
     7801 ccacttcgag ctggagcacc tgaccggggc caaggtcgcg accatggccg atgcgctggc
     7861 cgccgcgcgc agcctgctga aagggccgcg cctcgcattg atcaccagcc tgcgccgcgc
     7921 cgacgcaccg gccgaccagg tcgagatggt cgcggtgagc cgggacgcgg catggcgcat
     7981 cgcgacgccc ctgatcggtt tcgaggtcgc gcccaacgga acgggcgacg ccgtcgccgc
     8041 gttgttcttg gcgcactgga tcgaaagcgg cgatgtgccg gcagcactcg gcaaggcagc
     8101 gtcgtcgatc tacgccgtgc tcgaggccac gcgggccatg ggcgaacgtg aactccaact
     8161 cgtcgcggca caggatcgaa tgatcgcacc gtcccgccgc ttcactgccg aaaagctgta
     8221 gccggtcgat gaacgttccg ggctttcact tcaacccgat cgcgcttgcc atcgagggcg
     8281 cggccatcgg cttcctgatc gccgtgccgg tcgggccggc cgcagtgctg tgcatccggc
     8341 gctcgatcac ggtgggcgcc gtggcgggtt acatgaccgg cgtcggcgcg gcgctgggcg
     8401 atgcggtgtt cggcgcggtc gccgccttcg gcctgtcgat cgtcgagcag ttcgtcatcg
     8461 agcgcgagaa gtggcttctc ggcatcggcg gcatcggcct gatgatcatg ggctgggtga
     8521 ccatgcgcca caggccgcgc accgtcggcg acccggtggc cgacgaccgc gagcaccagg
     8581 tggcgacgca cttccactat gccagctcga gcttcttcat caccgtgttc aatccattga
     8641 ccgtgatggc cttcggcgcg gccttcgccg gccgcaacct tgcaggcgtc ggcgccaatc
     8701 tcgcggatgc agcgcttctg gtggcggcgg tattctgcgg cgcgctcgcc tggtgggcga
     8761 tcatctgcac ggcagccgta tcgctgcgcc accgcttcac cggggtcggc atgttgtggc
     8821 tgaaccgcgc ctcgggcgcc gtgatcctgg gcttcggcgt ggtggcgttg atctcgctgc
     8881 tgccgctgcc atggaagcag atcggtcacg cgctcgggct ctagtcccgt tatactggac
     8941 cgatgctgcc cgttctgctc gatcccacga aattccagga cgcgcttttg accgccaagg
     9001 gcgaggagcg tgcccatgtg gcgctgcggt cgctcgagac cctgtggttc aataccggca
     9061 cgctctgcaa tctcagctgc cagaactgct acatcgaatc ctcgccgcgc aacgaccggc
     9121 tggcctatct gtcggccgcc gaggtccggg tctacctcga cgagatcaag cgcgacggcc
     9181 acggcacgaa gctgatcggc ttcaccggcg gcgagccgtt catgaaccgc gagctgccgg
     9241 cgatgctcga ggatgtgctg tcgcgcggcc tgaaggcgat ggtgctgacc aacgccatga
     9301 agccgatgca caggatgaag cccgctttgc tcggcctgct ggcgcgctac ggccgcaacc
     9361 tcaccgtccg cgtctcggtc gaccactacg acaagacgct gcacgagaag gagcgcggag
     9421 cgcacacctg gaaaccgacc atcgacggcc tggtgtggct ggcgcaatcg ggcttcgacg
     9481 tccatgtcgc gggacggcac ttctcggacg agaccgacgc ccaagtgcgt gcgggctatg
     9541 cccggctgtt cgcagcgctc ggcattgcga tcgatgcggc gagccccgtg tcgctggtgc
     9601 tgtttcccga gatggacgcc cgggtcgatg ttcccgagat caccacggcc tgctggggca
     9661 tcctgaagaa gtcgccggac agcgtgatgt gcgcctcggc ccgcatggtg gtgaagcgca
     9721 agggcgcgac gcagcccgcc gtcgtcgcct gtaccctgtt gccctacgac ccgcagttcg
     9781 agctcggcaa caccttggcc gaaagcgtcg gcgccgtgcg cctcaaccat ccgcattgcg
     9841 ccaagttctg tgttttgggc ggcgcggcct gcagccagtg acgaccgaca tcgacgtcgt
     9901 cattccgacc ctgaacgctg cccgctccct ggcccatact ctcgaatccc tgaggggcga
     9961 ccacgacttg aagctgtcga tcacggtgtg cgacggcggc tcgcgcgacg atacggcgtc
    10021 gattgcgcgc caggcgggcg ccgccgtgct ggaaatcgag cccggtcgcg gcaagcagct
    10081 tgcggcgggc gcgatggcgg gcggcgcgcc gtggctcctc ttcctccacg ccgacacgag
    10141 gctgtcggcc ggatgggccg cggcagcgcg ccagctcatg gcgcggccgg cgcggaaagc
    10201 cggctacttc cgtctgcgct tcgactccgc cgatccacgc gcccgacgca tcgagagact
    10261 ggcggcctgg cgttgccgca ccttcggctt gccctatggc gaccagggcc tgctgatcga
    10321 gcgcgccttc taccagcaac tcggcggctt tcacgctttg cccttgatgg aggatgtcga
    10381 cttcgtgcgc cgcatcggcc ggcgcaatct cttgcctctc gatgccgacg ccatcacctc
    10441 ggccgcgcgc tacgaacgcg acggctggct cgcccggccg atgcgcaacc tcggctgcct
    10501 tgcgctctac tttgccgggc tgccgccgac cgtcatccgg cgcctgtacg gatgaagcgt
    10561 cacctcgtga tcttcgcccg cgtcccgcag ttcggacgcg tgaagcagcg gttggcggag
    10621 gcgatcggcc cgttggccgc gatgcgcttc tatcgccaga cgctcgatcg ccagatccgg
    10681 accttgtcgc gcgatcgccg ctggacggtc tggttgttcg tcacgcccga ccatgttctc
    10741 gaccacccgg cctggcaccg agcgaacgtg cgcggccagg gacgaggcga cctgggccga
    10801 cgcatgaagc ggccgtttcg tctgttgccg cccggccctc tcgtgctggt cggcagcgac
    10861 atcccggcga tgcagccgcg ccacatcgtg cgagcctttg cgctgctggg agaccatgac
    10921 ctggtgttcg gtccggcaac cgacggcggc ttctggctga tcggcgcgcg gcgcggccgg
    10981 cccttgccgc gttcgctgtt cgcgaaggtg cgatggtcga cgcagcatgc cctggccgac
    11041 acgctggcga cgattccgcc gggatacacg acggccatcg ccgatacgct cgacgatgtc
    11101 gacgatgcca atgatctgcg acgctggcac ggatgttgaa acgcccaacg ccttgccatc
    11161 ccgaagggag tgaaccccat gcccgcatcg ttcccgacgc agcctgccat cggtctgttc
    11221 gaggcgatct acaccgcccg ctcgctgcgg cacttcaagc ccgatccggt gccgccggcg
    11281 ctgatcgagc gcgtgctcga tgccgccatc cgcgcctcga gcggcggcaa cacgcagcac
    11341 tggaccttcc tcgtcgtgcg cgatgcggag aagcgccgcc agctcggcgc gctctaccgc
    11401 caggcatcgg actaccagag cgcggtctac gccgcacggc ccaagcccga gcacctgagc
    11461 gaagcgcagt acggacagtt cctcgccaac agcggctacc tctgggacca catggccgac
    11521 gcgccggtca tcctggtgcc ctgcctcgcg aggcgcgagc cgcccgagcg cacgagcctc
    11581 ccggaagtcg tgcaggcgcg ctatgccgat catctcgcca acgtccaacg gatcagcggg
    11641 tcgagcatct atccggcgat ccagaacgtc attctcgcct gccgggcgct cgggctcggc
    11701 acggtgatca cgaccaacca catcctgctc gagaacgagg tgaaggccgt gctcggcatc
    11761 cccgagcaca tcgccacgtt tgcgctgatg ccgatcggct atccgacgcg gaagtacggg
    11821 ccgctcaccc gcaagccggt ggccgaggtc acgtttgccg acacctgggg aaacccgtgg
    11881 cctgacacgg cagcaagcta ggaccgctgc ctaggaacgc tgcctaggac cgccgcttga
    11941 gctgctcgag ctcgcggcgc acgtcggcaa acaccgcatc ccagtcgccc ggccgcggct
    12001 ggcggaacag gcgcgcgctc ggataccacg gcgcgcgcgt gccgccgagc tgccagcgcc
    12061 agtcgaccgt cgacggcgac agcacccagg tctgaattcc cattgccgcc gccagatggg
    12121 cgatcggcgc gtcgatcgag atcaggaggt cgagctgcga cagcgccgtc gccgcctcgg
    12181 cgaaatcgaa gatgccgcgg ccgacatcgt gcaccaggcc gccggcgccg aaggtctgga
    12241 tgtccttctg atgcaccccg ccctgcaggc tgaacagcag caactcgggg tcgcccgaga
    12301 attccatgaa gcgcccgaac ggcaccgagc gctggcggtc ctgcggccgg ccgggcatgc
    12361 ccgcccagta gatgccgacg ctgagcttgg ccttctcgat gcggccgagc ttgatgcggc
    12421 tgtcgaccgg cgccttgagg taaggcgcct gcagggccgg cgcgtcgaag tcggcgcggc
    12481 agagatgcgg cagcgacacc atcgaggcat gcaggtcgaa gtcgggcaac ggctcgccct
    12541 cggcgacgac gtggtcgatg aaatcgacgg tgcccagaag atccttcagc agcgcctggc
    12601 agagcacgat gacggtggcg ccgcggcgct tgagctcacg ggcgaagcgc acgaacagca
    12661 gcacgtcgcc cagcccctgc tcgggataga gcaggatgcg cttgccgccg atcggtgcgc
    12721 cgtcccacgc cggttgccgg aaatccggcg ccggcgtctc gggcaggcgc ttgcgcgcct
    12781 cgtaggcggc gaagccctgt gccagctcac cacgcatcag cagcgcgagc gcaagctcga
    12841 cgcgggcgcg gcgattgtcg ggattgagcg ccagcgcgcg gccaaggcaa ccgaccgcct
    12901 cgtcgatgcg gccgagatcg cgcaggcaga gcgccagatt gaagaagccc tcgccgtagt
    12961 cgcggttgag cgtgatcgaa tggaagtgat gcttcaccgc ctcgtcgaga cggttggcgg
    13021 cgcgcagcgc attgccgagg ttggaatgca gcgcgggatt gtcgggatcg gctgccagcg
    13081 acaggcgatg atgcgacacc gaggcttcga gcttgcccgc gaggcgcaac gccacgccga
    13141 gattgttgtg cagctcggcg tgatagggcc gcacggccag gagcttgagg tacgaagtga
    13201 tcgcctcttc gagtcggccg gcgcgatggg cttgcgccgc cagtcgaagc tgctggacga
    13261 atgtgtcatc gccaccgaac aaaggcgttg gcacagcact ggcctgcgat tccgggcgga
    13321 gagggtaaag cgacgggatg tcgttcaccc tcttatctta catgaaatat cgttcttaac
    13381 cacctgtagt taaaagattt tcatttagat tcagagccat agaaggaatg ccgagaccaa
    13441 gcgcttgcag caaatccttc tactagatgt agccgcggat cagctcttcg gcgatctgca
    13501 cggcgttcag cgccgcgccc ttgcgcaggt tgtcgctgac gatccagagc gaaagcccgt
    13561 tgtcgaccgt gggatcggtg cgcacgcggc tcacgaacac gccgtcctgg ccggtgactt
    13621 cctgcggcgt gacgtagccg ccgttctcgc gacgatcgac gaccagcacg ccgggctggg
    13681 cggcgagcac gcggcgcgcc tcatgctcgt cgagcggccg ttcgagctcg aggttcaccg
    13741 cctcggcatg gccgatgaac accggcacgc gcacgcaggt cgcgtgcacc ttgatcttgg
    13801 gatcgaggat cttcttggtc tcgactacca tcttccactc ttccttggtc gagccgtcgt
    13861 ccatgaagac gtcgatgtgg ggaatgacgt tgaaggcgat gcccttggtg aatttcttgg
    13921 cctcgagcgt ctggttcacg aagaagctct tggtctggtt cagaagctcg tccatgcctt
    13981 ccttgccggc gcccgacgtc gactgatagg tcgacacgac aacgcgcttg atgccggcgg
    14041 cctcgtggat gggcttcagc gccaccacca tctggatggt cgagcagttg ggattggcga
    14101 tgatgccgcg ccccttgtag cccgcgatcg catgggcgtt gacctcgggc acgaccagcg
    14161 gcacgtcggg atccatgcgc cagtaggagg tgttgtcgat caccacggcg ccggccttgg
    14221 cggcgcgcgg gctgtgctcg gccgacacct tggcgccggg cgagctcagc acgatatcga
    14281 tgcccttgaa gtcgaacttg gcgaggtcct ggaccttgag cacgccattc tcgccgaacg
    14341 aggtctgctt gcccgccgag cgcgccgaag cgagtgccac gacgtcatcg gccgggaagt
    14401 tccgctcggc caggatctgc aacatttcgc gcccgacatt gccggtcgcg ccgacgacg
//
