LOCUS       NC_021039.1            22621 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021039.1 Ruminococcus champanellensis 18P13 = JCM 17042, complete
            sequence.
ACCESSION   NC_021039
VERSION     NC_021039.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:45:53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2211411
            Orig. end    :: 2234032
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22621
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2221411:2224032]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12621
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..22621
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22621
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="porA"
                     /region_number="5"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             917..2449
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2034"
                     /sec_met_domain="PLDc_2 (E-value: 2.1e-25, bitscore: 86.3,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLFKRIRDIITSRLFVTSFLILLQIIALILPFLYLGMRSVYIHA
                     VVGFISTVISLSIANDEKHAPFHTIWIVVLLAAPIAGWPLYVILRHNKQAGQASRRCAT
                     VSEHLDKIPFGGFQPDSLYACKHHPFHREMLHLARSCNAPVFTSTITRYFPNGESFFPV
                     YLEKLRTAKKFIFMEYFIINDGYLWQEVKKILTEKCRQGVEVRILYDDIATISKLTRSF
                     RRELRNMGVQVYPFNPYRAAVDSFMNYRDHRKITVIDGVIGFTGGINLADEYINKIERF
                     GYWKDAGLMLEGSAVQALTHTFLKSWGFVVKEDPMPQKYLIDKPQNADSLVQPFCDSPA
                     GKVRAGRDTYSSLINGAQRYVWITAPYLILENEMLNALCLAATSGVDVRIITPHIADKW
                     YVHAVTRSNYRALIKAGVKVYEYKPGFVHAKLIVADDAAAMVATTNFDYRSFYALFENG
                     VMVYGRDVIAQIKSDLTETMQQSMPYTMEMCQHTSRFRRSMRKLLRIFSPFL"
     CDS             2466..2777
                     /locus_tag="ctg1_2035"
                     /transl_table=11
                     /translation="MATSAEYAAFVCEQIAPYGQVRSRKMFGEYMVYLEDKPVLLVCDN
                     TVYVKKLPQVSDLLLTAPCGFPYEGAKEHYILDIENRELLDQLMPTLKASVSLPKKKK"
     CDS             complement(2906..3559)
                     /locus_tag="ctg1_2036"
                     /transl_table=11
                     /translation="MDISFLSKTWLFAGVEPEVLTKLLEQVHAYSRRFAKGEAVLHAGD
                     PVTHMGLVLQGSVLIAHEDLWGNRSILGRAASGEVFAETYACVTQEPLPMHVTAAEPTQ
                     VLFVHGAELLHAGTSGLSAPVTANLVRMLAQKNLNLSGKIRHITPKTIRGRLLSYLSAQ
                     SLRQSSYVFDIPFNRQQLADYLNVDRSAMCHELTRMQREGLVDFHKNSFRLIQR"
     CDS             3662..4360
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2037"
                     /sec_met_domain="Fer4_6 (E-value: 2.9e-07, bitscore: 27.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.013, bitscore: 13.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRRIIQIDEKKCNGCGMCANACHEGAIGMVNGKAKLLRDDYCDG
                     LGDCLPTCPTGAISFVEREAAAYDEAAVKAHQMQQAQSLPCGCPGTHAKRLHPVQEACS
                     HTASGQPSALQQWPVQIRLVPVHAPYFDQANLLIAADCTAYAYASMHQDFIRGRITLIG
                     CPKLDDADYAAKLTEILRSNTIQSVTVVRMEVPCCGGLEHAARTAVASTGNHVSFRVVT
                     ISTDGRILPE"
     CDS             4412..5014
                     /locus_tag="ctg1_2038"
                     /transl_table=11
                     /translation="MENRLEQQVAFIREIDKEKRIGRQTYLTGAIRKENDAEHAWHIAL
                     MAILLAEHANEPIDVLKTVTMLLIHDLVEIDAGDTYAYDTAAKATEQEREAKGADRIFG
                     MLPPDQGRAFRALWEEFNRGDTPEARFAHAMDNFQPVMLNAATDGKAWAEHGVRLSQIL
                     KRNQITPDGSTQLWEYAYQHFILPNVEQGRIRDDTNA"
     CDS             5120..6841
                     /locus_tag="ctg1_2039"
                     /transl_table=11
                     /translation="MFKLLAYMKNYKKEAVLGPLFKLLEALLELLVPLVIAAVIDTGIA
                     GGNRGYVIRMCLLLVGFGIVGLVFSITAQYFAAKASVGFVTKLRHALFDHIQGLSYTEL
                     DTIGTSTLITRMTSDMNQVQSGMNLTLRLLLRSPFVVFGAMIMAFTIDVKAALIFAAAI
                     PVLSLVVFGIMLWCIPLYKRVQRKLDGVLSATRENLTGVRVIRAFCKEEEQISRFDACN
                     QDLTRTQKYVGRISALMNPVTYILINLAIIWLVYTGALRVDVGLISQGAVVALYNYMSQ
                     ILVELIKLANLIINITKSVACGNRIQSVFEIRSSLDAPEQAPAPKDFSYAVEFDHVTLR
                     YANAGDDSLSDISFAARPGETIGVIGSTGSGKSSLVNLIPRFYDASAGQVLVDGINVKE
                     YPLDDLRNRIGVVPQKAVLFKGTIRDNLRWGNPDATDDQLLEAVQTAQAGEVLAQKGGL
                     DFELEQGGKNLSGGQKQRFTIARALVKHPKILILDDSASALDFATDAALRKAIREMPGN
                     PTVFIVSQRTSSLQHADQILVLEDGAVVGAGTHTQLLESCPVYQEIYQSQFRKEDA"
     CDS             6843..8600
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     289.3; E-value: 3.6e-88)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_2040"
                     /transl_table=11
                     /translation="MAKVQKGTIPKVWRYIRRYRLLLILSMLFAAATVAMTLYLPILIG
                     NAIDLIVSPGHVDFPGIRSLLIKIGIIAGCTGLTQWIMNMLNNRITYHIIRDVRQEAFG
                     KLQILPLSYLDAHPSGSILSRIIADVDQFADGLLMGFTQLFTGVVTILGTLLFMLSISW
                     KITLAVVLLTPLSLFIARFIARRTYSMFRLQSQVRGEQTALIDEMIGNQKVVQAFSHQA
                     ESMEQFDEINDRLARCSLQATFFSSITNPATRFVNSVVYASVALTGALMCISTAGAAVP
                     FTVGQLSCFLSYANQYTKPFNEISGVITELQNALACAARIFELIEETPQIPDQTDAAEL
                     EHVAGNLSISDVSFSYVPDRKLIEHLNLIVKPGQRIAIVGPTGCGKTTVINLLMRFYDV
                     DQGSISVEGKDIRNVTRHSLRSSYGMVLQETWLKAGTIRENICMGKPDATEEELLQASK
                     AAHAHSFIKRLPQGYDTLIGEDGGSLSQGQKQLLCIARVMLCLPPMLILDEATSSIDTR
                     TELKIQEAFSRMMQGRTSFIVAHRLSTIREADVILVMQDGHIIEQGNHDTLLAKNGFYA
                     NLYNSQFAR"
     CDS             8665..9945
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2041"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2.4e-15, bitscore:
                     54.5, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKRDVAVATVTAVLVLAIGGLICWVLYTHGIKGLSKPIMQTLTG
                     NNSQYAEEPATMPEDAPKWDSEQTESYPAIAAHMKLQGRTTRDEDQITWLVQSGSAAEF
                     TVTGTKAVLTLAGDRTALGKENHKPRYAVYLDDQLLTDALMRTKELEIPLFESNQPRTA
                     SVKVIQLSEAGYGAVGVKHVTVTSIYQEPVQPIPAKDLRIEFIGDSITCGYGVETKSEK
                     DSFTTGTENFTKTYAYLTARMLNADYSAVCYSGYGIVSGWTGDGQKKPDSILPKYYNLI
                     GILPKYKKQWDFEHAEQNDVVVINLGTNDYSYLSPSFSSRSKEFIKGYVDFLKQVRQKN
                     PNAYIFCTMGTMGGESVYGLIEQAVGEYSAATGDTRIKSYASPVQTQEDGYGADYHPSV
                     KTQQDSAQLLTEEICNTLGIQPGGSFQ"
     CDS             complement(10001..10531)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2042"
                     /sec_met_domain="POR (E-value: 1.4e-31, bitscore: 107.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYDILLAGFGGQGILFAGKLLAYCALIDGKELSWLPSYGPEMRG
                     GTCNCSVCISDEPIGSPLVLTPDLLIALNQPSYDKFIGSVRKGGMAFVDSTLVDTTVET
                     PDIQCFYVPATQMETDANLPKAANIILLGKLLKETGMFSDEVIRKGLEKLIPPKRAHLI
                     ENNLRAISMGMNV"
     CDS             complement(10531..11286)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2043"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-24, bitscore:
                     83.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATVFERPHALCDTPMHYCPGCTHGIVHRLLCEVLDEMGIEGETI
                     GVCPVGCSVFAYNYFNCDMIEAPHGRAPAVATGVKRSNPDKYVFTYQGDGDLAAIGTAE
                     TVHVGARGENIVVIFINNTIYGMTGGQMAPTTIPGQVTQTTPFGRDTELAGYPIRVCEM
                     MATLSGTALAQRVAVDTVPHIRETKKAIRKAFENQKEKRGLSIVEVLSTCPTNWGMTPL
                     EAIKRLQDECIPYYPLGVYKDVTAEGGEK"
     CDS             complement(11335..12366)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2044"
                     /sec_met_domain="PFOR_II (E-value: 2.2e-28, bitscore: 95.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.3e-53, bitscore: 177.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGNEALAEAAIRAGCKCFFGYPITPQTELSAYMAKRMHKEGGVF
                     LQAESEIAAINMVLGAASTGVRAMTSSSSPGISLKSEGISYIAGSDVPAVIINVQRGGP
                     GLGGIQPSQADYWQATKALGHGDFQLLVFAPSSVQEMVDMVVKAFDTADKYRMPAMILA
                     DGLLGQMMEPVQFPEIKANSIDKSSWAANGHGNKREHHIINSLYINATDLEEQVIERYK
                     RYDIIKENETDAELYLTEDADIVVCAYGATARVVKSAVNSARAEGIKVGMFRPKTLWPF
                     PVKEINQACQHASKLLCVEMSMGQMIDDVKLAINCSKPVSFFGRTGGVIPTPAEVLEHI
                     KSL"
     CDS             complement(12415..12621)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2045"
                     /sec_met_domain="Fer4_7 (E-value: 7.8e-08, bitscore: 30.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6e-07, bitscore: 26.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.5e-07, bitscore: 26.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKMTVLFERCKGCGLCTTACPKHIVAISKEKRNKKGYFTAACTD
                     DAACIGCAMCAMMCPDCAITVEK"
     CDS             complement(12676..13335)
                     /locus_tag="ctg1_2046"
                     /transl_table=11
                     /translation="MSNMKKITIVTGHYGTGKTNYSVNLALEAARTGEPVSIVDLDIVN
                     PYFRTADFGRLFAEHGVTMITPDYANSNVDIPVLNFDLERIASDPGYLIVDVGGDDAGA
                     TALGRYAEAFSQYADCLDMLYVINCYRYLTKTPQEALTMMYEIEQASHMKHTGIVNNSN
                     LGCETTVAHIESSLPFAQELARQADLPLLYTTYDDRLSPSGVGLHPVHVHVRPIWD"
     CDS             complement(13328..13978)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2047"
                     /sec_met_domain="CoA_binding (E-value: 8.5e-13, bitscore:
                     46.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKDSISHSVIRRMPRYYRFLGELERQGMIRISSRELAERMGLTA
                     SQIRQDLNCFGGFGQQGYGYNVTELHAQIGKILGVHAGNKTILIGVGNLGKAIAQHIDF
                     EKRGCKLIGIFDSNHALCGKQIAGVTVDPIETLEAFCAANHPVMAVLCIPKTAAHDLAH
                     QLVKLGVRAFWNFSHYDLRLEHEQEQIIVENVHLGDSLMTLAYGLQHQGDAHE"
     CDS             complement(13998..15209)
                     /locus_tag="ctg1_2048"
                     /transl_table=11
                     /translation="MSKIQMKTPLVEMDGDEMTRILWQWIKDILITPYVDLNVDYYDLG
                     LVHRNETSDQVTLDSAEATKKYGVAVKCATITPNAARMPEYNLKEMWKSPNGTIRAILD
                     GTVFRTPILVKGITPYIPTWTKPITIARHAYGDVYKNTEMQVKGGCKAELVVTDAEGKE
                     TRQLIHDFKTDGIIQGLHNIDQSIAGFARSCFSYGLDTKQDVWFATKDTISKKYDHRFK
                     DIFAEIFEAEYKEKFEAAGIEYFYTLIDDAVARVIRSNGGYIWACKNYDGDVMSDMVST
                     AYGSLAMMTSVLVSPTGVYEYEAAHGTVQRHYYKHLKGEETSTNSVATIFAWSGALRKR
                     GELDNIPELVRYADNLEQATIQTIEDGIMTGDLYLLSSLENKKKVNSKEFLEEINCRLA
                     KLMG"
     CDS             complement(15246..15458)
                     /locus_tag="ctg1_2049"
                     /transl_table=11
                     /translation="MYFLSTLPIMARHYRIRSTKDLILILIIAAVMYGVQTLCTKKFDM
                     EPRTARVIGIIAAMVVALILVFSFH"
     CDS             complement(15493..17430)
                     /locus_tag="ctg1_2050"
                     /transl_table=11
                     /translation="MGLTLTEKILKAHIVDGELIKGTEIGLRIDQTLTQDATGTMAYLE
                     YEAMGVPRVKTELSVAYIDHNTLQNGFENADDHRFIGSVTKKHGIRFSRPGNGICHQVH
                     LERFGIPGKTLIGSDSHTPTGGGIGMLAMGAGGLDVAVAMGGGAYYITCPKVVRVNLTG
                     KLSPWVAAKDVILEVLRRMSVKGGVGKVIEYCGEGVKTLSVPERATITNMGAELGATTS
                     IFPSDEVTREFLTAQGRGEVWTPLAADPDAVYDEELTIDLSQLVPMAACPHSPDNVKTV
                     AEIGSMKIDQVCIGSCTNSSLLDMLKVAYILKGKTVHPDVSLSIAPGSKQVLQMLAQNG
                     ALADMIAAGARILESACGPCIGMGQSPNSHGISLRTFNRNFEGRSGTRDGQIYLVSPEL
                     AAASALTGVLTDPRTLGEMPDFQLPKTFTVNDNMIELPAPESEMDKVEILRGPNIKPFP
                     QTSPLADSIDVPCSLKVGDNITTDHIMPAGAKILPLRSNIPAISEHCFTVCDPAFPTRA
                     KELGKSIIVGGANYGQGSSREHAALAPLYLGVKAVLVKSFARIHRANLINAGILPLTFA
                     NEADYDKIDQGDELELANVRKAIEAGESQLTLRDKTKGIDIPVLCELSGRTKDIVLAGG
                     LLDYTREALK"
     CDS             17686..18018
                     /locus_tag="ctg1_2051"
                     /transl_table=11
                     /translation="MLEFQTEEGILRVMLQGEIDHHSAGQLREQIDCRLEELLPKRLIL
                     DFTGVTFMDSSGIGLVMGRVRQAAAYGGQVEIAVPAGHIRKVMQLSGIDKLANIHAPVH
                     PAEQKG"
     CDS             18023..18463
                     /locus_tag="ctg1_2052"
                     /transl_table=11
                     /translation="MKTINEMKCTFPSLSVNEAYARTAVTAFAAQLDLTIEEIADIRTA
                     VSEAVTNAIVHGYRGTVGTIELCVKLLEGNEVYIRIKDSGCGIPDVAQAMEPLYTTAAA
                     EERAGLGFAVMESFMDKLSVKSKVGRGTTVVMRKRLGVTVPV"
     CDS             18460..19122
                     /locus_tag="ctg1_2053"
                     /transl_table=11
                     /translation="MSAPCSQPRAEENLGLVHLCANRFRGRGVEYDDLYSAGCIGLMKA
                     VNAFDTERGVRFSTYAVPVILGEIKRLFRDGGTVKVSRSMKELSMRVVRLRDELRMQSG
                     KEPTVQQLAREMGVEEAEIVQALCVSVPPVSLTDPGESGEGQLDIPVPPPDTEIGDVLA
                     LRQIMQTLSERDRMLLTMRYYQNKTQSQTAQALGMTQVQVSRREKKLLLTMREELLR"
     CDS             19161..19670
                     /locus_tag="ctg1_2054"
                     /transl_table=11
                     /translation="MTHYYYGNGKGKTTAALGMAVRAAGHGLPVCVVQFLKGSFSGEVK
                     SLGVLPQVTLIRLPKDYGFSFQMTQQQMQEITAQHSHMLESAAAWAKQHPDGLLILDEI
                     GDAVELKLIDVDLVKQLVMHPMAEQIYTGHAEQPLFTEHADYVTECRCVRHPHQSGVQA
                     RKGIEY"
     CDS             complement(19970..21472)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_25"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2055"
                     /sec_met_domain="Glyco_hydro_25 (E-value: 5.4e-37,
                     bitscore: 124.8, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTPVTKLIAAWAVSALMALQSTVYAADQTVQTGDIAVPEVSVGT
                     DAVAEQTSDVLNVSTKDINDTEGDLTETIRLPSCAQINQAICKSTQEPAADDTYDIDGN
                     GVINAFDNVLRKRQLLESQSEYAHLFVSKAVGYGGDVVPVTVSVSGNPGFQNFIMSFSM
                     TQGDYLTMQTGEDGNLKLTQPDQDLTLRAVSGGNVAAVYSTSAVRYTDNGELFTVYVEI
                     PEDTPVGVYPLEMVVQSIEESGNQKVPYVITQGTVTVREEVILPPVTTTTTTVPLETTT
                     TTTTTTTSTGPKGQIYDGIDVSKWQGTVDWAKVKADGYHFAIIRAGYGREASQVDPTFA
                     TNVAGAKKAGLYCGAYWYSYATDAAGAKAEAELFLKTVKGYQFDFPLVFDIEDSTQQSL
                     SKSTVAAIIDTFCSTVENAGYYCTLYSYASFLTNNVPVSCQSEHDIWVAHTKTEKPAFS
                     RAYGMWQYSHTGTVNGVSGSTDLNYAYKDYPAIMQKYGFNGF"
ORIGIN
        1 ctgacctcct tgatgcggga tatgtatgtg gacattcccg gcagggacaa aaataagatc
       61 aacgccgcat attccttcgg gggaccggag ctgctgatgg acaccatcca ggagaatctg
      121 ggtgtgaaga tcgatgacta tattgagatc agctttgttt ccttcgcctc tattgtggat
      181 gcagttggag gcgtggagat cacggtcagt gatgcggaag cacaggccat caaccagatc
      241 ctccaggacg aagtcaatgg cattctggga gatgcacgaa atgccgatct gctcagccag
      301 gggggcaagt atatcctcaa cggcaagcag gctctgtgct acagccggat ccggcatgtg
      361 ggcaatgcag actttcagcg tactgagcgg cagcgtgaag tgctgaccca gcttgtaacc
      421 agtctgaaaa actccggcgc tgccggcatg aagcggctca tgtcctccgc actgcctcag
      481 atccgcacca acatgaccaa gggagagctg taccagctgt ccctgcggat gcccttcctg
      541 ctgaactatg aaatgaccca gatccagatc ccggcagatg gcacctatac ggatgaccgg
      601 aacaccaacg caggctgggc actggtggtg gatctggacg ccaaccgtga gctgctgaag
      661 gaacaagtat tcgccgctga gtaaaggcaa taccgcacaa agcccgcctg tcggctttgc
      721 gtagcatctg ctgacgaatt ttccgtcata tcacacagaa actccttgca atacgccagt
      781 attcctgcgt cgtttctatg caatctgacg aaaaatctgt tggcacatct accacacaat
      841 ctttgtgcgg tgttgcctaa aaccatatga ttcattgggt gtacagacac ccagacatct
      901 gaagaaaggt tgcaacatgc agttattcaa acgaatccgt gatatcatta caagccgtct
      961 ttttgtcacc agctttctga tcctgctcca gatcattgcg ctgatcctgc cctttctata
     1021 tctgggcatg cgctccgtgt acattcacgc tgtcgtaggt ttcattagca cagtcatttc
     1081 cctgagcatt gccaacgatg aaaagcatgc gccctttcac accatctgga tcgttgtact
     1141 gttggctgca cccattgccg gatggcctct gtatgtgatc ctgcggcata acaagcaggc
     1201 aggtcaggcc agccgccgct gtgccacagt cagtgagcat ctggacaaaa tcccctttgg
     1261 cggttttcag ccggattccc tgtacgcctg caagcatcat cccttccatc gggaaatgct
     1321 ccatctggca cgcagctgca atgcacctgt atttaccagt accattaccc ggtatttccc
     1381 caatggtgaa agcttctttc cggtgtacct ggaaaagctg cgcactgcaa agaaattcat
     1441 tttcatggag tacttcatca tcaacgacgg ctatctgtgg caggaggtca aaaagatcct
     1501 gacggaaaag tgcagacagg gagttgaagt ccgaatcctg tatgacgaca ttgcaaccat
     1561 cagtaagctg acccgcagct tccgtcggga actgcgcaat atgggggttc aggtttaccc
     1621 ctttaatcca taccgggcag cggtggacag cttcatgaac taccgggatc accggaagat
     1681 cacagtcatt gacggggtaa tcgggtttac cggcggcatc aacctggcgg acgagtacat
     1741 caacaaaatc gaacgctttg gctactggaa ggatgcaggg ctgatgctgg agggtagtgc
     1801 tgtccaggca ctgacccata cctttttgaa atcctggggt tttgtggtca aagaggatcc
     1861 gatgccgcaa aagtatctga tcgacaagcc ccagaatgcg gacagcctgg tgcagccctt
     1921 ctgtgacagc cctgccggca aggtgcgtgc cgggcgggat acctactcca gtctgatcaa
     1981 cggcgcacag cggtatgtat ggatcactgc accctatctg attctggaaa atgaaatgct
     2041 caacgccctg tgtctggctg ctaccagtgg ggtggatgtg cgtatcatta ctcctcacat
     2101 tgcggacaag tggtatgtgc acgccgtgac ccgctccaac taccgggcac tgatcaaagc
     2161 cggcgttaag gtgtacgaat acaagcccgg ttttgtacat gcaaagctga tcgtggcaga
     2221 tgatgcggca gcaatggtgg caaccaccaa ttttgactac cggagttttt acgctctgtt
     2281 tgaaaacgga gttatggtat acggcaggga tgtgatcgcc cagatcaagt ctgacctgac
     2341 agaaaccatg cagcagtcca tgccctatac catggaaatg tgtcagcata cttcccggtt
     2401 ccgccgaagc atgcgcaagc tgctccggat cttctcgccg tttttgtaag aaaggggaaa
     2461 tggatatggc aacatccgca gagtatgctg catttgtatg tgagcaaatc gctccctatg
     2521 ggcaggttcg cagccggaaa atgttcggag aatatatggt ttacctggaa gacaagcctg
     2581 tgctactggt atgtgacaat accgtctatg tgaaaaagct gccccaggtg tcggatcttt
     2641 tattaacagc accatgcggt tttccctacg aaggagccaa ggaacattat atactggaca
     2701 ttgagaatcg agagttgctg gatcagctga tgcccacgct gaaggcttct gtgtctctgc
     2761 caaaaaagaa aaagtaagaa gaaccagtac gccgacaaag cgtactggtt cttatgattt
     2821 attcgcaatg tgtggtattt gctccagaca tggagcggcg gatgttgaaa aaataattag
     2881 ttgcattcgc acgcaggcgc tttgcttacc gctgaatcag ccggaaggaa ttcttatgaa
     2941 aatccaccag gccctcccgc tgcatccgtg tcagttcgtg gcacatggcg ctccggtcca
     3001 cattcaggta atccgccagc tgctgtcggt taaagggaat gtcaaacacg tagctggatt
     3061 gccggaggga ttgggcggat aaataggaca gcagtctgcc ccggatggtt ttgggagtaa
     3121 tgtgccggat ctttccggac aggttcaggt tcttctgcgc cagcatccgc acaagattgg
     3181 cagtaactgg cgctgacaaa ccggaggttc cggcatgcag cagctctgcg ccatgcacaa
     3241 ataacacctg ggtcggctct gccgctgtca catgcatggg cagcggttcc tgggtcacgc
     3301 aagcataggt ttccgcaaag acttctcccg aagcagctct gccaagaata ctccggttgc
     3361 cccacaaatc ctcatgggca atcagcacac tgccctgaag caccagtccc atatgggtca
     3421 ccggatctcc cgcatgcagc acggcttctc cctttgcgaa tctccggctg taagcatgca
     3481 cctgctccag taatttcgtc aaaacctccg gctccacgcc tgcaaagagc caggtcttgg
     3541 aaagaaaaga gatatccata agccctcctt tgttggaata acaacagatt tatcattctc
     3601 attatagtac aatgcataca gacggtcaag aacaccggtc aagaaaatgg aggattttaa
     3661 aatgatcaga agaatcattc agattgatga aaagaaatgc aatggctgcg gtatgtgcgc
     3721 aaacgcctgt cacgagggcg ccattggcat ggtgaacggc aaggcaaagc tgctgcggga
     3781 cgactactgt gatgggctgg gggactgcct gcccacctgt cccaccggtg ccatctcctt
     3841 tgtagagcgt gaggctgccg cctatgacga agcagcggtc aaagctcatc aaatgcagca
     3901 ggcgcagtcc ctgccctgcg gctgtcccgg tacccatgca aagcggctgc atcccgtaca
     3961 ggaagcatgc agccacacag cgtccggaca gccttccgct ttgcagcagt ggccggtaca
     4021 gatccggctg gttccggtgc atgcacccta ttttgatcag gcaaacctgc tgattgcagc
     4081 ggactgcaca gcctacgcct atgcgtccat gcaccaggat ttcatccggg gacggatcac
     4141 cctgatcggc tgtccgaagc tggatgatgc agattatgct gccaagctga cggagatcct
     4201 gcgcagcaac accattcaga gcgtaacggt agtgcgcatg gaggtaccct gctgtggcgg
     4261 actggagcat gctgcaagaa ccgctgtggc atccaccggc aatcacgttt ccttccgggt
     4321 ggtcaccatt tctacagatg gcaggatttt gccggaatag gcttgcataa gcagctctgt
     4381 tctgctatac tgataccagg aggcggaaca aatggaaaac agactggagc agcaggttgc
     4441 ttttatccgg gagatcgaca aggaaaagcg catcggcagg cagacttatc tgaccggggc
     4501 aatccgaaaa gaaaacgacg cagagcatgc ctggcacatt gcgctgatgg caattctcct
     4561 tgcagagcac gccaacgaac ccattgacgt tctgaaaaca gtgaccatgc ttctgatcca
     4621 tgacctggtg gagattgatg caggggatac ctatgcatac gatacggcag ccaaggcaac
     4681 ggaacaggag cgggaggcaa agggagcaga tcgtattttc ggcatgctgc ccccggatca
     4741 aggacgagca ttccgagcac tgtgggagga attcaaccgg ggagataccc cggaggcacg
     4801 gtttgcacat gccatggaca acttccagcc ggtgatgctg aacgccgcaa ctgacggaaa
     4861 agcctgggcg gagcatggtg tccggctcag tcagatcctg aaacggaatc agattacgcc
     4921 ggatggctct acccagttgt gggaatatgc ctatcagcat tttattctgc ctaatgtaga
     4981 gcaaggcagg atccgggacg atacaaatgc ataaccaaaa accgcaggat cctgcggttt
     5041 ttttatgccg gtaattcttg catgactgta ggaaacgtgg tataataaat gctgtattat
     5101 gctcgaaaga aggaacccta tgttcaaact attggcgtac atgaaaaact ataaaaaaga
     5161 ggcggtactg ggacctctgt tcaagctgct tgaggcattg ctggagctgc tggtgcccct
     5221 ggtgattgct gccgtcatcg acacaggcat tgccggcggc aaccggggat atgtgatacg
     5281 catgtgcctg ctgctggtgg ggtttggcat tgtgggactg gttttttcca tcaccgccca
     5341 gtactttgcc gccaaggcct ccgtcggttt tgtgacgaaa ctgcggcatg ccctctttga
     5401 ccacatacag gggctgtcct acacagagct ggacaccata ggcacctcca ccctcattac
     5461 ccgcatgacc agtgatatga accaggttca gtccggtatg aatctgaccc tccggctgct
     5521 gctgcgctct ccttttgtgg tatttggcgc catgattatg gcgttcacca ttgatgtaaa
     5581 ggcagcgctg atctttgcag ccgccattcc ggtgctgtcc ctggtggtat tcggcatcat
     5641 gctctggtgc atccccctgt acaaacgggt gcagcgaaaa ctggacggcg tgctcagtgc
     5701 aacccgggaa aacctcaccg gcgtccgggt gatccgtgcc ttctgcaagg aggaggagca
     5761 gatcagccgc tttgacgcct gcaatcagga tctgacccgg acacaaaagt atgtggggcg
     5821 gatctctgcg ctcatgaacc cggtgaccta cattctcatc aatcttgcaa tcatctggct
     5881 ggtgtatacc ggcgcccttc gggtggatgt gggactcatc tcccagggag ctgtggtagc
     5941 tctgtacaac tacatgtccc agattctggt ggaactgatc aagctggcaa acctgattat
     6001 caacatcacc aagtccgtgg catgcggcaa ccggatccag tccgtctttg agatccgttc
     6061 ctctctggat gcaccggaac aagcgcctgc accgaaggat ttctcctatg cagtggaatt
     6121 tgaccatgtt accctccggt acgcaaacgc cggggatgat tccttgtcag atatcagctt
     6181 tgctgcccgt cccggcgaaa ccatcggtgt catcggctcc accggctccg gcaaaagctc
     6241 tcttgtaaat ctgatccccc ggttctatga tgcatcggct ggacaggtat tggtggacgg
     6301 gatcaatgtc aaggagtatc ctctggatga tctgcgaaac cggatcggcg tagtgcccca
     6361 gaaggcagta ttgttcaaag ggacgatccg ggacaatctc cggtggggaa atccggacgc
     6421 tacggatgac cagctgctgg aagcggtaca gacagctcag gcaggggagg tgcttgccca
     6481 gaagggcgga cttgattttg aactagagca ggggggtaaa aacctgtccg gcgggcagaa
     6541 acagcggttc accattgcaa gagccctggt gaagcatccg aagatcctga ttttagacga
     6601 cagtgcctct gctttggatt ttgcaacgga tgcggcactg cgaaaggcga tccgggaaat
     6661 gccaggcaat cccacagtat tcatcgtgtc ccagcgaacc tcctccctgc agcatgcaga
     6721 tcagatcctg gtattggagg atggagcagt ggtaggcgcc ggcacccata cacagctgct
     6781 ggaatcctgc ccggtatacc aggagatcta tcaatcccag ttccggaagg aggatgcgta
     6841 atatggcaaa ggtacagaag gggacaatcc ccaaggtgtg gcggtatatc cgccggtatc
     6901 ggctactgct gatcctgtcc atgctgtttg cagccgcaac cgttgccatg accctatatt
     6961 tgcccatcct gatcgggaac gccattgatc tgatcgtttc tccggggcat gtggactttc
     7021 ccggcatccg atcgctgctc atcaaaatcg gtatcatcgc cggatgcacc ggactgaccc
     7081 agtggatcat gaatatgctc aacaaccgga tcacctatca cataatccgg gatgtgcggc
     7141 aggaagcctt cggcaagcta cagatccttc ctttgagcta tctggatgcc cacccctccg
     7201 gcagcatcct cagccggatc atcgcagacg tggatcagtt tgcagacggt ctgctgatgg
     7261 gctttaccca gttgttcacc ggggttgtta ccattctggg caccctgttg ttcatgctgt
     7321 ccattagctg gaagatcacg ctggcagtgg tgctgctgac acctctgtcc ctgttcattg
     7381 cccggttcat tgcccgccgc acctacagca tgttccggct acagtcccag gtacggggag
     7441 agcaaacggc actgatcgat gaaatgattg gaaaccagaa ggtggtgcag gcattctccc
     7501 accaggcaga gagcatggag cagttcgatg aaatcaacga tcgtcttgcc cgatgctccc
     7561 tgcaggctac cttcttttcc tccatcacca atccggcaac ccgctttgtc aacagcgtgg
     7621 tctatgcaag cgtggcgctg acaggcgctt tgatgtgtat ttccactgcc ggagccgctg
     7681 tgccctttac ggtaggacaa ctgtcctgct tcctgtccta cgcaaaccag tataccaagc
     7741 ccttcaacga gatctccggt gtcattaccg agctgcagaa cgcccttgca tgtgctgcac
     7801 ggatctttga actgatcgag gaaacacccc agatcccgga tcagacagat gctgccgaac
     7861 tggagcatgt ggcagggaac ctgtccattt cagatgtatc cttctcctat gtgccggatc
     7921 ggaagctaat cgagcatctg aatctcatcg tcaagcccgg acagcgcatt gccattgtgg
     7981 ggcccaccgg ctgcggcaag actaccgtca tcaatctgct gatgcggttt tatgatgtgg
     8041 atcaagggtc tatctccgtg gaagggaagg acatccggaa cgtcacacga cacagcctgc
     8101 gcagcagcta cggcatggtc ttgcaggaaa cctggctgaa ggcaggaacc atacgggaaa
     8161 atatctgtat gggaaagcca gatgccacag aggaagaact gcttcaggca tccaaagctg
     8221 cacatgccca cagcttcatc aagcgactgc cccaggggta tgacaccctg atcggagagg
     8281 atggaggcag cctgtcccag ggacaaaagc agcttctgtg cattgccaga gtgatgcttt
     8341 gcctgccccc catgctgatt ctggatgagg caacctcctc cattgatacc cgaacggagc
     8401 tgaagatcca ggaggcattc tcccggatga tgcaggggag aaccagcttt attgtggcac
     8461 accggctttc caccatccgg gaggcggatg tgatcctggt gatgcaggat ggtcacatca
     8521 ttgaacaggg gaatcacgac acacttcttg caaaaaatgg tttttatgca aacctgtata
     8581 acagtcaatt tgcccggtaa atgctgactg ttaatattta ctaggatgtt tattataatg
     8641 ttgaggaata ggaggcagca ggctatgaga aagagagacg ttgccgttgc tacagtcacc
     8701 gccgttctgg tactggcgat cggcggattg atctgctggg ttttatatac acacggcata
     8761 aagggtctga gtaagcccat tatgcagact ctcaccggga acaacagtca atatgcagaa
     8821 gaaccggcaa ccatgccgga ggatgcgccc aaatgggaca gtgagcagac agaaagctac
     8881 cctgccattg cagcccatat gaaattacag ggcagaacca cgcgggacga ggatcagatt
     8941 acctggctgg tgcagagcgg ttctgccgca gaatttacag taaccggcac gaaagccgtt
     9001 ctgaccctgg caggggacag aaccgcactt ggcaaggaaa accacaagcc ccggtatgca
     9061 gtgtatctgg acgatcagct gctgacggat gcactgatgc gcaccaagga gctggagatc
     9121 cctctgtttg aatccaacca gcccagaacc gccagtgtca aggtaatcca gctttcggaa
     9181 gccggatacg gagcggtcgg tgtgaagcat gtaaccgtta catccattta ccaggagccg
     9241 gtacagccca ttccagccaa ggatctgcga atcgaattta tcggagattc catcacctgc
     9301 ggctatggcg tggaaaccaa atcggaaaag gactccttca ccaccggtac ggagaatttc
     9361 accaaaacct atgcctacct aacagcccgg atgctgaatg cggattacag cgccgtatgc
     9421 tacagcggtt acggcatcgt ttccggctgg acaggggatg ggcaaaaaaa gccggacagc
     9481 attctgccaa agtattataa tctgatcggg atcctgccca aatacaaaaa acagtgggat
     9541 tttgagcatg cggagcagaa tgacgtggtg gtcatcaacc ttggcaccaa cgattactcc
     9601 tatctgagtc ccagcttttc cagccgttcc aaggagttta tcaagggata tgtggacttt
     9661 ctcaagcagg tacgtcagaa gaatccaaat gcctacattt tctgcaccat gggtaccatg
     9721 ggaggggaat cggtgtacgg attgatcgag caggcagtgg gggaatacag cgccgccacc
     9781 ggagacaccc ggatcaaaag ctatgcctct ccggttcaga cccaggagga cggctatggc
     9841 gccgattatc acccttccgt caaaacccag caagacagcg cccagctgct cacggaggaa
     9901 atctgcaaca ccctgggcat ccagcccggc ggcagctttc agtaagagac agaaaaagcc
     9961 ccttcatgca tttcgcatga aggggcttgc tttataaaat ttacacattc attcccatgc
    10021 tgatggcacg caggttgttt tcaatcagat gcgcacgctt cggggggatc agcttctcca
    10081 gacccttgcg gatcacttca tcggagaaca taccggtttc cttgagcagc ttgcccagca
    10141 gaatgatgtt tgctgccttg ggcaggtttg catcggtttc catctgggtt gcgggcacgt
    10201 agaagcactg aatatccggt gtttccacag tggtgtccac cagagtgctg tccacaaatg
    10261 ccatgccgcc cttgcgaaca ctgccgatga acttatcgta ggaaggctga ttcagtgcga
    10321 tcagcaaatc cggtgtcaaa accaggggag aaccgatggg ctcgtcagag atgcaaacgg
    10381 agcagttaca ggtaccgcca cgcatttccg gaccgtagga cgggagccag gacagctcct
    10441 tgccgtcgat cagcgcacag tatgcgagga gcttgccggc gaacagaata ccctgaccgc
    10501 caaagccagc cagcagaata tcatatttca ttacttttct cctccttcag ctgtaacatc
    10561 cttatatacg cccagcgggt agtaggggat gcactcatcc tgcagacgct tgattgcctc
    10621 cagcggagtc atgccccagt tggtcgggca ggtggagagt acttctacaa tggacaggcc
    10681 acgcttttcc ttctggttct caaatgcctt gcgaatcgcc ttcttggttt cccggatgtg
    10741 gggaacggta tctacagcaa cacgctgtgc caaagcagta ccactgaggg tagccatcat
    10801 ctcgcatacc cggatcgggt agccggcaag ctctgtgtca cggccgaagg gggtggtctg
    10861 ggtaacctga cccggaatgg tggtaggtgc catctgcccg ccggtcatgc cgtaaatggt
    10921 gttgttgatg aagatcacaa cgatgttctc gcctcttgcg ccaacatgaa cggtttccgc
    10981 agtaccaatg gcagccaggt cgccgtcgcc ctgataggtg aacacgtact tgtccgggtt
    11041 ggaacgctta acgccggttg caacagccgg tgctctgccg tggggcgctt ctatcatatc
    11101 acagttgaaa taattgtaag caaatacgga gcagccaacc ggacatacac cgatggtctc
    11161 gccctcaatg cccatctcat ccagaacttc gcacagcagt ctatgtacaa taccatgggt
    11221 acagccagga cagtagtgca tcggcgtgtc gcaaagtgcg tggggtcttt caaatacagt
    11281 agccatttta tttcaagatt ctccttgcag gagaacccac tcctttcgca aaatttagag
    11341 gctcttgata tgttccagga cttcagccgg agtcgggatc acaccaccgg ttctgccgaa
    11401 gaaggaaaca ggcttggaac agttgatcgc cagcttgaca tcatcgatca tctgacccat
    11461 ggacatttct acgcacagca gcttggatgc gtgctggcaa gcctggttga tctccttgac
    11521 cgggaagggc cacagggtct tgggacggaa catgccgacc ttgatgccct ctgcacgggc
    11581 gctgtttact gcggacttta ccacacgggc ggtcgcaccg tatgcacata ccacaatgtc
    11641 agcatcctca gtcaggtaca gttcagcgtc ggtctcattc tccttgatga tgtcgtaccg
    11701 cttgtagcgc tcaatgacct gctcttccag gtcggtagca ttgatgtaca gggagttgat
    11761 gatgtggtgt tcacgtttgt tgccatgacc gtttgcagcc caggaggact tgtcaatgct
    11821 gtttgccttg atttctggga actgaaccgg ctccatcatc tgacccagca gaccgtctgc
    11881 caggatcata gcaggcatcc ggtacttgtc ggctgtgtca aacgccttga caaccatgtc
    11941 caccatttcc tgtacggagg aaggagcaaa tacaagcagc tggaagtcac cgtgacccag
    12001 cgccttggta gcctgccagt agtcagcctg ggaaggctgg ataccgccca gacccgggcc
    12061 gcctctctgc acgttgatga tcactgccgg aacatcggaa ccggcaatgt aggaaatgcc
    12121 ctcagacttc agggagatcc cgggagaaga ggaggaggtc atagcccgaa cgccggtgga
    12181 agcagcgccc agtaccatgt tgatggctgc gatttcggac tcagcctgca ggaacacgcc
    12241 gccctccttg tgcatgcgct ttgccatata tgcggaaagc tcagtctggg gcgtaatggg
    12301 gtaaccgaag aaacacttac agccggctct gatggctgct tcagcaagag cttcattgcc
    12361 cttcataaga tttttttcca agatgcgaaa cttcctttct ttccaacaag tggattactt
    12421 ttcaactgta attgcgcagt ccgggcacat catagcgcac attgcacagc cgatgcatgc
    12481 cgcatcatct gtacaggcag cagtgaagta gcctttcttg ttgcgctttt cctttgaaat
    12541 cgcaacaatg tgcttcgggc aggctgtggt gcaaagcccg cagcccttgc agcgctcaaa
    12601 caatactgtc atcttagcca tggtctgatt ctcctttccg gaaaaaatgt tattggttgc
    12661 aaggggtggc agccgttagt cccagatggg acggacatgc acatgaaccg gatgcagccc
    12721 cacacctgat ggcgatagtc gatcgtcata ggtcgtgtac aaaagtggaa gatccgcctg
    12781 ccgtgccagt tcctgggcaa agggcaggga ggactcgata tgggcaacgg tggtttcaca
    12841 gcccagattg gaattgttga cgattccggt atgcttcata tgggaagcct gctcgatttc
    12901 gtacatcatc gtcagggctt cctggggggt cttggtcaga taacggtagc agttgatcac
    12961 atagagcatg tccaggcagt cggcatactg cgagaatgcc tctgcatagc ggcccaatgc
    13021 ggttgcgcct gcatcgtctc cacccacgtc cacgatcaga tagcccggat cggatgcgat
    13081 ccgctccaga tcaaaattca gaaccggaat gtccacattg ctgtttgcat aatccggcgt
    13141 gatcatggtg acaccgtgct cggcaaaaag cctgccgaaa tccgcagtgc gaaaataggg
    13201 attgacgata tccagatcca cgatgctgac aggctccccg gtacgggcag cctccagcgc
    13261 cagatttacg gaataattgg ttttaccggt gccgtaatgc ccggttacaa tggtgatttt
    13321 tttcatatta ctcatgtgca tccccttgat gctgcaagcc gtaggcaagt gtcatcaggc
    13381 tgtcgcccag atgcacattt tctacgatga tctgttcctg ttcatgctcc agccgcaggt
    13441 catagtgact gaagttccag aaggcccgaa cccccagctt caccagctga tgcgccaggt
    13501 catgggcggc ggttttcgga atgcaaagca cagccataac cggatgattt gcggcgcaga
    13561 acgcctccag ggtttcgatg ggatccaccg tgaccccggc aatctgctta ccgcacagag
    13621 cgtggttgct gtcgaaaata ccgatcagct tacagccccg cttttcaaaa tcaatgtgct
    13681 gcgcaatggc ttttccaagg ttgcctacgc caatgagaat ggtcttgttg cctgcgtgca
    13741 cgccaagaat ctttccgatc tgggcgtgaa gctccgtcac attataaccg tagccctgct
    13801 gtccgaagcc gccgaagcag ttcagatcct gacggatctg ggaagcggtc agccccatac
    13861 gctctgcaag ctcccgggag gagatccgga tcattccctg acgttccagt tcaccgagaa
    13921 agcgatagta acggggcatc cgacgaatca ccgaatgaga gatactatct tttgccatgc
    13981 gattgccttt ccgggattta gcccatcaac tttgccagac ggcagttgat ttcctccagg
    14041 aactccttgg agttcacctt cttcttgttt tccagactgg acagcaggta tagatcccct
    14101 gtcatgatgc cgtcttcaat ggtctggatg gttgcctgct ccagattatc cgcatagcga
    14161 accaactccg gaatgttgtc cagctcgcca cgcttgcgga gcgcaccact ccatgcaaag
    14221 atggttgcaa cggagttggt ggaggtctcc tcacccttca gatgcttgta gtaatgacgc
    14281 tgaactgtgc catgtgcagc ttcatattca tacacgccgg tgggggatac cagaacggaa
    14341 gtcatcatag ccaggctgcc ataagcggtg gataccatgt cggacatcac atccccgtcg
    14401 tagttcttgc atgcccagat ataaccgccg ttggaacgga ttacccgtgc cactgcatca
    14461 tcgatcaggg tgtagaaata ttcaatgccg gctgcttcaa acttttcctt gtactccgct
    14521 tcaaagatct ctgcgaaaat atccttgaac cggtggtcgt acttcttgga aatggtgtcc
    14581 tttgtggcaa accatacatc ctgcttggtg tccagaccgt aggagaagca ggaacgggca
    14641 aatccggcaa tggactggtc aatgttgtgc agaccctgga taatgccgtc tgtcttgaaa
    14701 tcgtggatca gctgacgggt ttccttgccc tcagcatcgg tcacaaccag ctccgcctta
    14761 cagccgccct tcacctgcat ctcggtgttc ttgtacacat ccccgtaagc gtgacgggcg
    14821 atggtaatgg gctttgtcca ggtaggaatg tagggggtaa tgcccttaac caggatgggg
    14881 gtacggaaca cggtaccatc caggatggca cggatggtgc cgttggggga cttccacatt
    14941 tccttcaggt tgtattcggg cattcttgct gcgttgggtg taatggtagc gcactttaca
    15001 gccacaccgt atttcttggt ggcttctgcg ctgtccaggg tcacctggtc actggtttca
    15061 ttccggtgaa ccagtcccag gtcgtagtaa tccacattca gatccacata gggcgtgatg
    15121 agaatatcct tgatccactg ccacaggatc cgggtcattt cgtccccgtc catttcgacc
    15181 aggggcgttt tcatctgaat tttgctcatt ggggtatacc tccttgtatg aaatgctgta
    15241 ttgccttagt gaaaggaaaa aaccaaaatc aaagcaacaa ccattgctgc aattatgccg
    15301 attactctgg cagtacgagg ctccatatca aacttcttgg tgcagagggt ctgcacgccg
    15361 tacatgaccg ctgcgataat caggatcagg atcagatcct tggtagagcg aatgcggtag
    15421 tgccgagcca taatcggcag agtggagaga aaatacatgg tttgattcct ctttctgtta
    15481 tgaaataggg tcttacttca atgcttctct ggtgtaatcc agcagaccgc ccgccagtac
    15541 gatatcctta gttctaccgc tgagctcaca cagcactgga atgtcaatgc ccttggtctt
    15601 atcccggagg gtcagctggg attctccggc ttcaattgcc ttgcgtacat tcgccaactc
    15661 cagttcatcc ccctggtcga tcttgtcgta atccgcttcg ttggcaaagg tcagaggcag
    15721 gataccggca ttgatgaggt ttgcacggtg gatccgggca aaggacttca ccagtacagc
    15781 cttgactccc agatacagcg gtgcgagagc cgcatgctca cgggaagagc cttgaccata
    15841 gtttgcgccg cccacaataa tggacttgcc cagttccttt gcacgggtcg ggaatgcagg
    15901 atcgcaaacg gtaaagcaat gctcactgat tgccggaata ttggagcgca ggggcagaat
    15961 ctttgcgcct gcgggcatga tgtggtcggt ggtgatattg tcccccacct tcagggaaca
    16021 gggaacgtcg atgctgtccg ccaggggact ggtctggggg aagggcttga tgttgggacc
    16081 gcgcagaatc tccaccttgt ccatttcaga ttccggtgca ggcagttcga tcatattatc
    16141 attgactgta aaggtcttgg gtagctggaa gtccggcatc tcgcccaggg ttctggggtc
    16201 agtcagcacg ccggtgagag cggatgcagc agcaagctcc ggagaaacca gatagatctg
    16261 accgtcccgt gtaccggagc ggccttcaaa gttccggttg aaggtacgca gagaaatgcc
    16321 gtgggaattg ggggactgtc ccataccaat gcagggaccg catgcgcttt ccaggatccg
    16381 tgcgccggct gcgatcatat ctgccagtgc gccgttctgt gccagcatct gcaatacctg
    16441 cttggagccg ggggcaatgg acagggaaac gtccggatgc acggtcttgc ccttgaggat
    16501 ataagccacc ttcagcatat ccagcagact ggagttggtg caggaaccga tgcatacctg
    16561 gtcgatcttc atggagccga tctccgcaac ggtcttgaca ttgtccgggg aatggggaca
    16621 tgctgccata ggcaccagct gactcagatc aatggtcagt tcctcgtcgt atacagcatc
    16681 cggatccgct gccaggggcg tccagacctc acctctgccc tgtgcagtga ggaattccct
    16741 ggtcacttcg tcagagggga agatggaagt tgtagcaccc agctcagcgc ccatattggt
    16801 aatggttgca cgctccggta cggacagggt cttgacaccc tcaccgcagt actcgatgac
    16861 cttacccacg ccgcccttga cggacatccg gcgcagaacc tccaggatca catcctttgc
    16921 agcaacccaa ggagaaagct tgccggtcag attgacacga accaccttgg gacaggtaat
    16981 gtagtatgca ccaccgccca ttgccactgc aacgtccagt ccgcctgcgc ccattgccag
    17041 catgccgatg ccgccgccgg tgggggtatg actgtcggag ccgatcaagg tcttgcccgg
    17101 gatgccgaac cgctccagat gtacctggtg gcagataccg ttgcccggac gggagaagcg
    17161 aatgccgtgc ttcttggtca cgctgccgat aaaacgatgg tcgtctgcat tttcaaagcc
    17221 gttctgcagt gtgttatgat cgatgtatgc cacagaaagc tctgttttga ctctgggtac
    17281 ccccattgcc tcgtattcca gataagccat tgttcccgtt gcatcctgcg tcagcgtctg
    17341 gtcgatgcgc agaccgatct cggtaccctt aatcagttcg ccatccacaa tgtgcgcctt
    17401 cagaattttt tcggttagtg tcagacccat tgcgttcacc ctttcgaatc agaatataca
    17461 aaataagaat acgcttccga acagccgtaa ctgtttcgga tacttcttta ttttactaca
    17521 ttttcagcac acttgtcaag aaattcacag taaaaagcac ctatcaaaaa aatggacagc
    17581 aggtttcaac aaaattcgca tgcagttggg ggtataattg tgacaaagcg caagggcggc
    17641 aaaagcagtg ccgttcgaca ggcaaataac aaggaggcgt attttatgct ggaatttcaa
    17701 acggaggaag ggatactgcg ggtcatgctg cagggcgaga tcgatcacca cagtgcggga
    17761 cagctgcggg agcagatcga ctgccgactg gaggagctgc tgccaaagcg gctgatcctg
    17821 gattttaccg gtgtgacctt tatggacagc tccggcatcg gcttggtgat gggcagagtc
    17881 cggcaggctg ccgcatacgg gggacaggtg gagatcgcag ttcctgccgg tcacatccgg
    17941 aaggtcatgc agctgtccgg cattgacaaa ctggcaaaca tacatgcgcc ggtgcatccg
    18001 gctgagcaga aaggataatc aaatgaaaac gatcaatgaa atgaaatgca cctttccatc
    18061 cctgtcggtg aatgaggcgt acgcacgcac agcagtaacc gcatttgccg ctcagctgga
    18121 tctgaccatt gaggaaattg cagatatccg gacggcggta tccgaagcgg taacgaacgc
    18181 catcgtacac ggataccggg gcacggtggg caccatagag ctgtgcgtca agctgctgga
    18241 gggcaatgag gtgtacatac gcatcaagga cagcggatgc ggcattccgg acgtggcaca
    18301 ggctatggag cctctgtaca ccactgccgc cgctgaggaa cgtgccgggc ttggcttcgc
    18361 cgtcatggaa agcttcatgg acaagctgtc cgtcaaaagc aaggtgggca ggggcacaac
    18421 cgtggtcatg cgcaagcggc tgggcgtgac ggttcccgta tgagtgcgcc ctgctcacaa
    18481 ccccgtgcag aggaaaacct ggggctggtg catctttgcg ccaaccggtt ccggggacga
    18541 ggtgtggaat atgacgacct gtattctgct ggatgtatcg gcttgatgaa agcagtcaac
    18601 gcctttgaca cggaacgagg cgtgcggttt tccacctatg cagtgccggt aatacttggg
    18661 gagatcaagc ggctgttccg ggacggaggc acagtcaagg tcagccggag catgaaagag
    18721 ttgtccatgc gggtggtgcg tctgcgggac gagctgcgca tgcaaagcgg caaagagccc
    18781 actgtgcagc aactggcaag ggagatgggg gtagaggaag cagagatcgt ccaggcattg
    18841 tgcgtcagcg tgccaccggt atccctgaca gatccggggg aaagcgggga aggacaactg
    18901 gatatcccgg taccgccgcc ggatacggaa atcggagacg tgctggcgct gcgacagatc
    18961 atgcagaccc tttccgaacg ggataggatg ctgctgacca tgcggtatta tcagaacaag
    19021 acccagtccc agactgcaca ggctctgggc atgacccagg tacaggtatc cagacgggag
    19081 aagaagctgc tgctgaccat gcgggaggag ttgttgcgct gaagcggatt ccgtgatata
    19141 atcaagctga ggtgacgaca atgacgcatt actattatgg caacggaaaa ggaaagacca
    19201 ccgcagcatt gggaatggct gtacgagccg ccggacatgg tcttccggta tgtgtggtac
    19261 aatttctcaa gggcagcttc agcggagaag tgaaaagcct tggggttttg ccccaagtga
    19321 cactgatacg cctgccaaag gattacggat tcagctttca gatgacgcaa caacaaatgc
    19381 aggagatcac agcccagcac agccacatgc tggaatcagc tgctgcatgg gccaagcaac
    19441 atccggatgg actgctgatc ctggacgaga tcggagatgc ggtggagctg aaattgatcg
    19501 atgtagatct ggtgaagcag cttgtgatgc atcccatggc ggagcagatt tacaccggac
    19561 atgcagaaca gccgctgttt acagaacatg cggattatgt gacagaatgc agatgtgtac
    19621 ggcatccaca tcagtccggc gtccaggcac gaaaaggcat tgaatattga atgatcggcg
    19681 ctcatgcgga ggtttcgtcc gtgtgggcgt tttgtttcaa aaaagaatgc tgtaagggat
    19741 ggtacacttg tccttgcaac aaaaaacacg ctttgcgccc agtgccaaga agccccttgc
    19801 atgcaggaga cactacccag cttgcacgaa tactaactgc acaaaatata tgttttgtgc
    19861 agttgatgag aaaaacaaga ccgatgagcc taaaatggag tcgacgtcta ccaacagaaa
    19921 aaaaccagag tgtgaaatca tcacactctg gctatctgat cattgcacct taaaacccat
    19981 taaatccgta tttctgcatg attgccggat aatctttata ggcataattc aagtccgtac
    20041 taccggatac gccgttgacc gttccggtat ggctgtattg ccacatccca tatgcacgag
    20101 aaaaagcggg cttttcggtt tttgtatgcg ccacccagat atcatgctcc gattgacagg
    20161 ataccggcac attattggtc aaaaatgacg cataactata cagcgtacaa taatatcctg
    20221 cattttccac cgtgctgcaa aacgtatcaa tgatcgctgc aacggtgctc ttactcaagg
    20281 actgctgggt gctgtcctca atatcaaaaa ccagcgggaa atcaaactga tatcccttta
    20341 cagttttcaa aaacaattcc gcctccgctt tagcccctgc tgcatctgtc gcatagctgt
    20401 accagtatgc accacagtac agcccggctt tttttgctcc tgcaacattc gttgcaaagg
    20461 tgggatccac ctgggaagcc tccctgccgt agccggcacg aatgatcgca aaatggtaac
    20521 catccgcctt aacctttgcc caatccactg tgccctgcca cttggaaaca tcaatgccgt
    20581 cataaatctg tcccttaggg cctgtggagg ttgttgtagt agtggtagtt gtcgttgttt
    20641 ccaaaggaac cgtcgttgtg gtagtagtca ccggcggcag gatcacttcc tcccgcactg
    20701 taacggtgcc ctgtgtgatc acataaggca ccttctggtt cccggattct tcaatggact
    20761 gcacgaccat ctccagcgga tacacaccaa cgggcgtatc ctccgggatc tccacatata
    20821 ccgtaaacaa ttcaccatta tccgtatacc gtaccgctga agtggagtat accgctgcca
    20881 cattgccgcc ggatactgca cgaagtgtca gatcctgatc cggctgggtc agcttcaggt
    20941 ttccgtcctc gccggtctgc atggttaaat agtccccttg ggtcatgctg aagctcataa
    21001 taaaattctg aaagccagga tttccggaca cagatacagt caccggcacc acatcgccgc
    21061 catagcccac cgccttggac acaaacaaat gtgcatactc agactgggac tcaagcagct
    21121 gccgtttccg cagcacatta tcaaaagcgt taattacgcc gttgccgtca atatcatatg
    21181 tatcatctgc tgcgggctcc tgcgtagatt tgcagattgc ctgattgatc tgcgcgcagc
    21241 tgggcaggcg gatcgtttcg gtcagatccc cctcagtgtc gttgatatct tttgtgctga
    21301 cattcaaaac atcagaggtt tgctcagcaa cagcatccgt ccccacagat acttccggca
    21361 cagcaatgtc ccctgtctgt acagtctgat ctgccgcata aaccgttgac tgtaaagcca
    21421 tcagagccga tacagcccat gcagcaatca gctttgtaac tggtgttttc ataacatact
    21481 ccctctttgc taacgctgtt caatctaact acatatagta taacataaaa tgcgcaattt
    21541 gtgaagtaca ttaggcgaat tttttgtgca tttctacata ttgcatgatt tacaaccgaa
    21601 aatttagccg agattacgaa gagcaaaaaa gtattttcga aaaaaacaga tttttttgaa
    21661 aaaagggatt gacattttca aaaagatgcg gtataataat aaagcactcg ggagagagcg
    21721 caaaacaaaa aagaacatgc tgttttagct cagttggtag agcacttcct tggtaaggaa
    21781 gaggtcgctg gttcgaatcc agtaaacagc tccagaacac agcacgcagt tccattggaa
    21841 ttgcgtgctt tttggttata caagtatctt ttacgttagg aatgttttgg taaaaagaat
    21901 ttttatacag catgacccat tctatccctg aaattcgttt attatggtga aagaactttg
    21961 cgaaaggaat catacacaat gcttgcttat ttcaaaatga aacggatttg ccgggaatat
    22021 gcgcaacaaa atcttcggga cgctgaagac tggttcgcta aatacgatgc gggaaagcct
    22081 catgctttct cccgggaatt tcagatcaag ctgaatactg ccatttacgg tgaggccttt
    22141 acagatgcag aaatcaacga ctacctgcat ccggtatgca gaccggctcc gaagactgac
    22201 ggtcggcaga tccggctcaa acggcttggc atgcgctatg cagctgcaat cattaccgct
    22261 gccgtattga ccaccagtgc tctggtagga ctgggtggtg tcattgccga tccgcagagc
    22321 tgcaatgatg tacagttctc ttctgtcaag tccggctgct ttgacaatat ggtggcaggg
    22381 tttctttatc cttcagagta ctataactcc agcaaattta acgggcacgt tatggagggt
    22441 catccggatc atgtttcccc gttccagttc gcctctgttc ccgaagggtt tgaactgaaa
    22501 tccatgcacg catactccac ggactctgca aaaggtgaaa tcgagctgaa cggtaactgg
    22561 gatcaggtaa atcggattga ttacactttc acaaatgaaa ctatgggttg gttatatatt
    22621 a
//
